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Search of human proteins with 225703079
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225703079 membrane bound O-acyltransferase domain containing
7 isoform 1 [Homo sapiens]
(472 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225703079 membrane bound O-acyltransferase domain containing ... 979 0.0
gi|225703081 membrane bound O-acyltransferase domain containing ... 754 0.0
gi|225703033 membrane bound O-acyltransferase domain containing ... 754 0.0
gi|225703037 membrane bound O-acyltransferase domain containing ... 713 0.0
gi|40548387 O-acyltransferase (membrane bound) domain containing... 117 2e-26
gi|122937404 membrane bound O-acyltransferase domain containing ... 111 2e-24
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi... 82 1e-15
gi|189571629 membrane bound O-acyltransferase domain containing ... 47 5e-05
gi|45439337 porcupine isoform E [Homo sapiens] 44 3e-04
gi|45439333 porcupine isoform C [Homo sapiens] 44 3e-04
gi|45439329 porcupine isoform A [Homo sapiens] 44 3e-04
gi|45439335 porcupine isoform D [Homo sapiens] 41 0.003
gi|45439331 porcupine isoform B [Homo sapiens] 41 0.003
gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens] 30 3.6
gi|223890259 midline 2 isoform 2 [Homo sapiens] 29 8.1
gi|223890257 midline 2 isoform 1 [Homo sapiens] 29 8.1
gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens] 29 8.1
gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo ... 29 8.1
gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo ... 29 8.1
gi|239750588 PREDICTED: hypothetical protein XP_002347440 [Homo ... 29 8.1
gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo ... 29 8.1
gi|239744885 PREDICTED: hypothetical protein XP_002344275 [Homo ... 29 8.1
>gi|225703079 membrane bound O-acyltransferase domain containing 7
isoform 1 [Homo sapiens]
Length = 472
Score = 979 bits (2532), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT 60
MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT
Sbjct: 1 MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT 60
Query: 61 WALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQ 120
WALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQ
Sbjct: 61 WALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQ 120
Query: 121 DLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQP 180
DLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQP
Sbjct: 121 DLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQP 180
Query: 181 FPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFA 240
FPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFA
Sbjct: 181 FPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFA 240
Query: 241 FRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR 300
FRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR
Sbjct: 241 FRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR 300
Query: 301 NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHP 360
NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHP
Sbjct: 301 NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHP 360
Query: 361 GYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLA 420
GYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLA
Sbjct: 361 GYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLA 420
Query: 421 DTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 472
DTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE
Sbjct: 421 DTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 472
>gi|225703081 membrane bound O-acyltransferase domain containing 7
isoform 2 [Homo sapiens]
Length = 399
Score = 754 bits (1946), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 112 LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 171
LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR
Sbjct: 39 LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 98
Query: 172 TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 231
TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL
Sbjct: 99 TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 158
Query: 232 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 291
FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS
Sbjct: 159 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 218
Query: 292 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL 351
LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL
Sbjct: 219 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL 278
Query: 352 SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC 411
SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC
Sbjct: 279 SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC 338
Query: 412 MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE 471
MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE
Sbjct: 339 MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE 398
Query: 472 E 472
E
Sbjct: 399 E 399
>gi|225703033 membrane bound O-acyltransferase domain containing 7
isoform 2 [Homo sapiens]
Length = 399
Score = 754 bits (1946), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 112 LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 171
LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR
Sbjct: 39 LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 98
Query: 172 TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 231
TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL
Sbjct: 99 TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 158
Query: 232 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 291
FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS
Sbjct: 159 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 218
Query: 292 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL 351
LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL
Sbjct: 219 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL 278
Query: 352 SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC 411
SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC
Sbjct: 279 SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC 338
Query: 412 MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE 471
MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE
Sbjct: 339 MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE 398
Query: 472 E 472
E
Sbjct: 399 E 399
>gi|225703037 membrane bound O-acyltransferase domain containing 7
isoform 3 [Homo sapiens]
Length = 344
Score = 713 bits (1841), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT 60
MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT
Sbjct: 1 MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT 60
Query: 61 WALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQ 120
WALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQ
Sbjct: 61 WALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQ 120
Query: 121 DLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQP 180
DLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQP
Sbjct: 121 DLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQP 180
Query: 181 FPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFA 240
FPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFA
Sbjct: 181 FPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFA 240
Query: 241 FRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR 300
FRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR
Sbjct: 241 FRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR 300
Query: 301 NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR 344
NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR
Sbjct: 301 NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR 344
>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
[Homo sapiens]
Length = 520
Score = 117 bits (293), Expect = 2e-26
Identities = 118/464 (25%), Positives = 192/464 (41%), Gaps = 60/464 (12%)
Query: 34 AAAVGLGLTLFTCGPHTLHSLVTI-LGTWALIQAQPCSCHALALAWTFSYLLFFRA--LS 90
A +GL L LF G + LH LV + +I + H + YL + +
Sbjct: 60 ATLLGLYLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVY 119
Query: 91 LLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLM 150
+ + + +++T K+ SLA E+ D + +E+ S + PSL+
Sbjct: 120 IFDYGQYSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRM----PSLL 175
Query: 151 ETLSYSYCYVGIMTGPFFRYRTYLDWLEQPF-----PGAVPSLRPLLRRAWPAPL----- 200
E LSY+ ++GI+ GP Y+ Y+ ++E G R P+P
Sbjct: 176 EYLSYNCNFMGILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQ 235
Query: 201 ------FGLLFLLS-SHLFPLEAVREDAFYARPL-PARLFYMIPVFFAFRMRFYVAWIAA 252
LLF L+ P+E ++ F A P ++ Y+ A R ++Y AW A
Sbjct: 236 KLLVCGLSLLFHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLA 295
Query: 253 ECGCIAAGFG--AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFC 310
+ AAGFG Y AR ++ I N+ +
Sbjct: 296 DAINNAAGFGFRGYDENGAAR------------------------WDLISNLRIQQIEMS 331
Query: 311 VRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-I 369
+ + WN+ WL + Y+ R+ + T +LSA WHG++PGYYL+FLT +
Sbjct: 332 TSFKMFLDNWNIQTALWLKRVCYE----RTSFSPTIQTFILSAIWHGVYPGYYLTFLTGV 387
Query: 370 PLCLAAEGRLESALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWAS 428
+ LAA + + P K +D + W + A Y + FVLLS+ +L +++S
Sbjct: 388 LMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSS 447
Query: 429 IYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 472
Y+C+H L + L L L RRK + L+ K +E
Sbjct: 448 WYYCLHILGILVL---LLLPVKKTQRRKNTHENIQLSQSKKFDE 488
>gi|122937404 membrane bound O-acyltransferase domain containing 1
[Homo sapiens]
Length = 495
Score = 111 bits (277), Expect = 2e-24
Identities = 108/431 (25%), Positives = 187/431 (43%), Gaps = 59/431 (13%)
Query: 34 AAAVGLGLTLFTCGPHTLHSLVTILGTWAL-IQAQPCSCHALALAWTFSYLLFFRALSLL 92
A G+ +F G +++H V +L +A+ + A + H + YL +
Sbjct: 68 ATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIY 127
Query: 93 ----GLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPS 148
G+ T T F+ + +++T K+ +LA +V D L +R E S + + P S
Sbjct: 128 IFHYGILT-TDFSGPL-MIVTQKITTLAFQVHD-GLGRRAEDLSAEQHRLAIKVKP---S 181
Query: 149 LMETLSYSYCYVGIMTGPFFRYRTYL---------------DWLEQPFPGAVPSLRP--- 190
+E LSY ++ ++ GP ++ Y+ +W + F ++P P
Sbjct: 182 FLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFH-SLPEPSPTGA 240
Query: 191 LLRRAWPAPLFGLLFLLSSHLFPLEAVREDAF-YARPLPARLFYMIPVFFAFRMRFYVAW 249
++ + + LLFL + FP+ + +D F + PARL Y+ V A + ++Y AW
Sbjct: 241 VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAW 300
Query: 250 IAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDF 309
A+ AAGFG V + ++ + N++ + +
Sbjct: 301 TLADAVNNAAGFGFSGVDKNGN----------------------FCWDLLSNLNIWKIET 338
Query: 310 CVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT- 368
+ + WN+ WL Y+ P VL T +LSA WHG++PGYY +FLT
Sbjct: 339 ATSFKMYLENWNIQTATWLKCVCYQRVPWYPTVL----TFILSALWHGVYPGYYFTFLTG 394
Query: 369 IPLCLAAEGRLESALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWA 427
I + LAA + LS KA +D W + A Y FV+L++ T+ +
Sbjct: 395 ILVTLAARAVRNNYRHYFLSSRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYK 454
Query: 428 SIYFCIHFLAL 438
S+YF +H ++L
Sbjct: 455 SMYFYLHIISL 465
>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
sapiens]
Length = 487
Score = 82.0 bits (201), Expect = 1e-15
Identities = 106/428 (24%), Positives = 168/428 (39%), Gaps = 63/428 (14%)
Query: 38 GLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTF--SYLL---FFRALSLL 92
GL + F G HSL+ I+ + +++ + A+ + F +YLL ++ A
Sbjct: 78 GLSIAYFNFGNQLYHSLLCIVLQFLILRLMGRTITAVLTTFCFQMAYLLAGYYYTATGNY 137
Query: 93 GLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMET 152
+ P +LTLKL+ LA + D Q ++S K G VPSL+E
Sbjct: 138 DIKWTMP-----HCVLTLKLIGLAVDYFDGGKDQNS-LSSEQQKYAIRG----VPSLLEV 187
Query: 153 LSYSYCYVGIMTGPFFRYRTYLDWLEQ---PFPGAVP-SLRPLLRRAWPAPLFGLL--FL 206
+SY Y + GP F Y+ ++ PG +P S+ P L+R LF L+ L
Sbjct: 188 AGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIPGKIPNSIIPALKRL-SLGLFYLVGYTL 246
Query: 207 LSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYV-AWIAAECGCIAAGFGAYP 265
LS H+ + ED + P R YM+ ++ F + YV W+ E CI G G
Sbjct: 247 LSPHITEDYLLTED-YDNHPFWFRCMYML-IWGKFVLYKYVTCWLVTEGVCILTGLGFNG 304
Query: 266 VAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQ 325
K +A ++ N+ + + R + +N+
Sbjct: 305 FEEKGKA----------------------KWDACANMKVWLFETNPRFTGTIASFNINTN 342
Query: 326 WWLAQYIYKSAP-ARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEGRLESALR 384
W+A+YI+K + L ++L A WHGLH GY + F L + E + ++
Sbjct: 343 AWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQ 402
Query: 385 GR-----------LSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCI 433
L P +HW Y F L + L+ + SIYF
Sbjct: 403 ESPTLSKLAAITVLQPFYYLVQQTIHWLF----MGYSMTAFCLFTWDKWLKVYKSIYFLG 458
Query: 434 HFLALAAL 441
H L+ L
Sbjct: 459 HIFFLSLL 466
>gi|189571629 membrane bound O-acyltransferase domain containing 4
[Homo sapiens]
Length = 435
Score = 46.6 bits (109), Expect = 5e-05
Identities = 77/351 (21%), Positives = 136/351 (38%), Gaps = 64/351 (18%)
Query: 55 VTILGTWALIQAQPCSCHALALA---------WTFSYLLFFRALSLLGL---------PT 96
V +G++A++ P C L WTF + + ++ L LGL P
Sbjct: 53 VAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPP 112
Query: 97 PTPF--TNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLS 154
F T + +LLT ++ SL+ ++ + + K + GF +L V + S
Sbjct: 113 SVRFCITLSSLMLLTQRVTSLSLDICE---GKVKAASGGFRSRSSLS--EHVCKALPYFS 167
Query: 155 YSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPL 214
Y + ++ G ++ + Q +L P R ++ A + L +L +
Sbjct: 168 YLLFFPALLGGSLCSFQRF-----QARVQGSSALHP--RHSFWALSWRGLQILGLECLNV 220
Query: 215 EAVREDAFYARPLPARLFYMIPVFFA----FRMRFYVAWIAAECGCIAAGFGAYPVAAKA 270
R A + F I V + F++ +Y WI + AAGFG
Sbjct: 221 AVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFG-------- 272
Query: 271 RAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQ 330
P L P E Y + + D ++ + R+ R WN + WL +
Sbjct: 273 -----PELGQSPG---------EEGY--VPDADIWTLERTHRISVFSRKWNQSTARWLRR 316
Query: 331 YIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEGRLES 381
+++ + R++ L T SA+WHGLHPG F+ + + A+ + S
Sbjct: 317 LVFQHS--RAWPLLQ--TFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHS 363
>gi|45439337 porcupine isoform E [Homo sapiens]
Length = 379
Score = 43.9 bits (102), Expect = 3e-04
Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 45/254 (17%)
Query: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200
G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L
Sbjct: 73 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 128
Query: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 259
L +LS+ + P Y+ P F R W+ A ++
Sbjct: 129 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 169
Query: 260 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 314
F Y V A AG G T E+ LE+D + ++ V V
Sbjct: 170 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 219
Query: 315 DGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLA 374
+ WN+ + +WL Y++K+A T SA H G+ + L LA
Sbjct: 220 --VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAVLLSLA 273
Query: 375 AEGRLESALRGRLS 388
+E LR RL+
Sbjct: 274 FITYVEHVLRKRLA 287
>gi|45439333 porcupine isoform C [Homo sapiens]
Length = 455
Score = 43.9 bits (102), Expect = 3e-04
Identities = 64/259 (24%), Positives = 95/259 (36%), Gaps = 50/259 (19%)
Query: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200
G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
Query: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAF------RMRFYVAWIAAEC 254
L +LS+ + P Y+ P F R V W+ A
Sbjct: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKGTMVRWLRAYE 240
Query: 255 GCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDF 309
++ F Y V A AG G T E+ LE+D + ++
Sbjct: 241 SAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRS 291
Query: 310 CVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTI 369
V V + WN+ + +WL Y++K+A T SA H G+ +
Sbjct: 292 MVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAV 344
Query: 370 PLCLAAEGRLESALRGRLS 388
L LA +E LR RL+
Sbjct: 345 LLSLAFITYVEHVLRKRLA 363
>gi|45439329 porcupine isoform A [Homo sapiens]
Length = 450
Score = 43.9 bits (102), Expect = 3e-04
Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 45/254 (17%)
Query: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200
G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
Query: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 259
L +LS+ + P Y+ P F R W+ A ++
Sbjct: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 240
Query: 260 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 314
F Y V A AG G T E+ LE+D + ++ V V
Sbjct: 241 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 290
Query: 315 DGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLA 374
+ WN+ + +WL Y++K+A T SA H G+ + L LA
Sbjct: 291 --VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAVLLSLA 344
Query: 375 AEGRLESALRGRLS 388
+E LR RL+
Sbjct: 345 FITYVEHVLRKRLA 358
>gi|45439335 porcupine isoform D [Homo sapiens]
Length = 461
Score = 40.8 bits (94), Expect = 0.003
Identities = 66/261 (25%), Positives = 98/261 (37%), Gaps = 48/261 (18%)
Query: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200
G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
Query: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMR--------FYVAWIAA 252
L +LS+ + P Y P Y IP+ +R V W+ A
Sbjct: 200 ALLCLVLSTCVGP---------YLFP------YFIPLNGDRLLRNKKRKARGTMVRWLRA 244
Query: 253 ECGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYST 307
++ F Y V A AG G T E+ LE+D + ++
Sbjct: 245 YESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELP 295
Query: 308 DFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFL 367
V V + WN+ + +WL Y++K+A T SA H G+
Sbjct: 296 RSMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLA 348
Query: 368 TIPLCLAAEGRLESALRGRLS 388
+ L LA +E LR RL+
Sbjct: 349 AVLLSLAFITYVEHVLRKRLA 369
>gi|45439331 porcupine isoform B [Homo sapiens]
Length = 456
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%)
Query: 141 GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 200
G + VPS +E + Y Y I+ GP+ + +YL Q G S R L + A L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199
Query: 201 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 253
L +LS+ + P Y+ P F + W+ A
Sbjct: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240
Query: 254 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 308
++ F Y V A AG G T E+ LE+D + ++
Sbjct: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291
Query: 309 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 368
V V + WN+ + +WL Y++K+A T SA H G+
Sbjct: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344
Query: 369 IPLCLAAEGRLESALRGRLS 388
+ L LA +E LR RL+
Sbjct: 345 VLLSLAFITYVEHVLRKRLA 364
>gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]
Length = 1088
Score = 30.4 bits (67), Expect = 3.6
Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 7/44 (15%)
Query: 260 GFGAYPVAAKARAGGGPTLQCPPPSSPE----KAASLEYDYETI 299
G GA+P+ + GGP +CPPP P+ ++ S +YD +++
Sbjct: 496 GAGAFPLDVEY---GGPDRRCPPPPYPKHLLLRSKSEQYDLDSL 536
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 29.3 bits (64), Expect = 8.1
Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 3/69 (4%)
Query: 287 EKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTV---QWWLAQYIYKSAPARSYVL 343
E + + E CY + + G YW + + W+ YKSAP ++
Sbjct: 530 ESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIG 589
Query: 344 RSAWTMLLS 352
++A + + S
Sbjct: 590 KNASSWVFS 598
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 29.3 bits (64), Expect = 8.1
Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 3/69 (4%)
Query: 287 EKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTV---QWWLAQYIYKSAPARSYVL 343
E + + E CY + + G YW + + W+ YKSAP ++
Sbjct: 560 ESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIG 619
Query: 344 RSAWTMLLS 352
++A + + S
Sbjct: 620 KNASSWVFS 628
>gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]
Length = 325
Score = 29.3 bits (64), Expect = 8.1
Identities = 12/34 (35%), Positives = 23/34 (67%), Gaps = 1/34 (2%)
Query: 293 EYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQW 326
+YD+E +RN++ ++T +CV+VR + N +W
Sbjct: 172 QYDFEVLRNLEPWTT-YCVQVRGFLPDRNKAGEW 204
>gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo
sapiens]
Length = 755
Score = 29.3 bits (64), Expect = 8.1
Identities = 15/35 (42%), Positives = 17/35 (48%)
Query: 252 AECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSP 286
AEC AG P+AA+ R P C P SSP
Sbjct: 349 AECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383
>gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo
sapiens]
Length = 755
Score = 29.3 bits (64), Expect = 8.1
Identities = 15/35 (42%), Positives = 17/35 (48%)
Query: 252 AECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSP 286
AEC AG P+AA+ R P C P SSP
Sbjct: 349 AECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383
>gi|239750588 PREDICTED: hypothetical protein XP_002347440 [Homo
sapiens]
Length = 510
Score = 29.3 bits (64), Expect = 8.1
Identities = 45/171 (26%), Positives = 59/171 (34%), Gaps = 33/171 (19%)
Query: 1 MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT 60
+SP T L L G+L+ P G A V G+ H + LV L T
Sbjct: 345 VSPPPGTGLSSLARPSGSGWLWPNVPPTCGNAGLAVVSQGVPAGAGAHHRVLFLVAELVT 404
Query: 61 WALIQAQ--PCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASE 118
++QA PC C A W + L +R LG P +
Sbjct: 405 VPVVQAAELPCDCKGEA-RWLWGQLEKWR----LGWPKGASY------------------ 441
Query: 119 VQDLHLAQRKEMASGFSKGP----TLGLLPDVPSLMETLSYSYCYVGIMTG 165
+HL + A G SKGP + G P ME Y C + I G
Sbjct: 442 ---IHLPVSHKAAIGLSKGPEPGDSCGRKPIFQGCMEAFIYE-CGLIIFAG 488
>gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo
sapiens]
Length = 755
Score = 29.3 bits (64), Expect = 8.1
Identities = 15/35 (42%), Positives = 17/35 (48%)
Query: 252 AECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSP 286
AEC AG P+AA+ R P C P SSP
Sbjct: 349 AECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383
>gi|239744885 PREDICTED: hypothetical protein XP_002344275 [Homo
sapiens]
Length = 510
Score = 29.3 bits (64), Expect = 8.1
Identities = 45/171 (26%), Positives = 59/171 (34%), Gaps = 33/171 (19%)
Query: 1 MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGT 60
+SP T L L G+L+ P G A V G+ H + LV L T
Sbjct: 345 VSPPPGTGLSSLARPSGSGWLWPNVPPTCGNAGLAVVSQGVPAGAGAHHRVLFLVAELVT 404
Query: 61 WALIQAQ--PCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASE 118
++QA PC C A W + L +R LG P +
Sbjct: 405 VPVVQAAELPCDCKGEA-RWLWGQLEKWR----LGWPKGASY------------------ 441
Query: 119 VQDLHLAQRKEMASGFSKGP----TLGLLPDVPSLMETLSYSYCYVGIMTG 165
+HL + A G SKGP + G P ME Y C + I G
Sbjct: 442 ---IHLPVSHKAAIGLSKGPEPGDSCGRKPIFQGCMEAFIYE-CGLIIFAG 488
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.140 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,341,692
Number of Sequences: 37866
Number of extensions: 959896
Number of successful extensions: 3476
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3440
Number of HSP's gapped (non-prelim): 27
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.