Guide to the Human Genome
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Search of human proteins with 115430227

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115430227 LYR motif containing 5 [Homo sapiens]
         (90 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115430227 LYR motif containing 5 [Homo sapiens]                    183   3e-47
gi|10092689 LYR motif containing 2 [Homo sapiens]                      40   3e-04
gi|38570054 LYR motif containing 4 [Homo sapiens]                      35   0.016
gi|190194370 LYR motif containing 1 [Homo sapiens]                     30   0.31 
gi|190194368 LYR motif containing 1 [Homo sapiens]                     30   0.31 
gi|10092683 LYR motif containing 1 [Homo sapiens]                      30   0.31 
gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ...    29   0.69 
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    28   1.5  
gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo sapi...    27   2.6  
gi|116008154 hypothetical protein LOC201229 [Homo sapiens]             27   2.6  
gi|239787106 zinc finger protein 610 isoform b [Homo sapiens]          26   5.9  
gi|14150167 hypothetical protein LOC84319 [Homo sapiens]               26   5.9  
gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo sap...    26   7.7  
gi|19718759 myoferlin isoform b [Homo sapiens]                         26   7.7  
gi|7305053 myoferlin isoform a [Homo sapiens]                          26   7.7  
gi|55743134 ribosomal protein S6 kinase, 90kDa, polypeptide 1 is...    25   10.0 
gi|20149547 ribosomal protein S6 kinase, 90kDa, polypeptide 1 is...    25   10.0 
gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Ho...    25   10.0 
gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]    25   10.0 
gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...    25   10.0 
gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...    25   10.0 
gi|31377581 hypothetical protein LOC124989 [Homo sapiens]              25   10.0 

>gi|115430227 LYR motif containing 5 [Homo sapiens]
          Length = 90

 Score =  183 bits (464), Expect = 3e-47
 Identities = 90/90 (100%), Positives = 90/90 (100%)

Query: 1  MKMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGE 60
          MKMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGE
Sbjct: 1  MKMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGE 60

Query: 61 FVMKELEALYFLRKYRAMKQRYYSDTNKTN 90
          FVMKELEALYFLRKYRAMKQRYYSDTNKTN
Sbjct: 61 FVMKELEALYFLRKYRAMKQRYYSDTNKTN 90


>gi|10092689 LYR motif containing 2 [Homo sapiens]
          Length = 88

 Score = 40.4 bits (93), Expect = 3e-04
 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 8  RGEVLKLYKNLLYLGRDYPKGAD--YFKKRLKNIFLKNKDVKNPEKIKELIAQGEFVMKE 65
          R +VL LY+ +L   R  P  +D  Y K   +  F +NK     + I+ +I QG   +KE
Sbjct: 19 RQQVLLLYRRILQTIRQVPNDSDRKYLKDWAREEFRRNKSATEEDTIRMMITQGNMQLKE 78

Query: 66 LEALYFLRK 74
          LE    L K
Sbjct: 79 LEKTLALAK 87


>gi|38570054 LYR motif containing 4 [Homo sapiens]
          Length = 91

 Score = 34.7 bits (78), Expect = 0.016
 Identities = 19/56 (33%), Positives = 34/56 (60%), Gaps = 2/56 (3%)

Query: 3  MANSLRGEVLKLYKNLLYLGRDYP--KGADYFKKRLKNIFLKNKDVKNPEKIKELI 56
          MA S R +VL LY+ +L   + +       Y  +R+++ F +NK+VK+P +I+ L+
Sbjct: 1  MAASSRAQVLSLYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLV 56


>gi|190194370 LYR motif containing 1 [Homo sapiens]
          Length = 122

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 10/64 (15%)

Query: 3  MANSLRGEVLKLYKNLLYLGR----------DYPKGADYFKKRLKNIFLKNKDVKNPEKI 52
          M  + R EVL LY+++  L R          D  K   Y     + +F KNK++ + + I
Sbjct: 1  MTTATRQEVLGLYRSIFRLARKWQATSGQMEDTIKEKQYILNEARTLFRKNKNLTDTDLI 60

Query: 53 KELI 56
          K+ I
Sbjct: 61 KQCI 64


>gi|190194368 LYR motif containing 1 [Homo sapiens]
          Length = 122

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 10/64 (15%)

Query: 3  MANSLRGEVLKLYKNLLYLGR----------DYPKGADYFKKRLKNIFLKNKDVKNPEKI 52
          M  + R EVL LY+++  L R          D  K   Y     + +F KNK++ + + I
Sbjct: 1  MTTATRQEVLGLYRSIFRLARKWQATSGQMEDTIKEKQYILNEARTLFRKNKNLTDTDLI 60

Query: 53 KELI 56
          K+ I
Sbjct: 61 KQCI 64


>gi|10092683 LYR motif containing 1 [Homo sapiens]
          Length = 122

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 10/64 (15%)

Query: 3  MANSLRGEVLKLYKNLLYLGR----------DYPKGADYFKKRLKNIFLKNKDVKNPEKI 52
          M  + R EVL LY+++  L R          D  K   Y     + +F KNK++ + + I
Sbjct: 1  MTTATRQEVLGLYRSIFRLARKWQATSGQMEDTIKEKQYILNEARTLFRKNKNLTDTDLI 60

Query: 53 KELI 56
          K+ I
Sbjct: 61 KQCI 64


>gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor
           [Homo sapiens]
          Length = 1419

 Score = 29.3 bits (64), Expect = 0.69
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 16/90 (17%)

Query: 2   KMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIF----------LKNKDVKNPEK 51
           KMA  LR E+L+LY+  + L  ++    +  +   KN F          +K+ +V+NPE+
Sbjct: 611 KMAQ-LRAELLQLYERCILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKDPNVENPEQ 669

Query: 52  IK----ELIAQG-EFVMKELEALYFLRKYR 76
           I+    EL+ +G +F    L+ L    K++
Sbjct: 670 IRNRLLELLDEGSDFFDSLLQKLQVTYKFK 699


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 20/85 (23%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 1    MKMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGE 60
            ++ AN  R EV+K  + L    +DY +  +  +     IF ++K+  + +K+K L A+  
Sbjct: 1633 IEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKE--SEKKLKSLEAEIL 1690

Query: 61   FVMKELEALYFLRKYRAMKQRYYSD 85
             + +EL +    R++   ++   +D
Sbjct: 1691 QLQEELASSERARRHAEQERDELAD 1715


>gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo
          sapiens]
          Length = 256

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 15/45 (33%), Positives = 27/45 (60%), Gaps = 4/45 (8%)

Query: 26 PKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGEFVMKELEALY 70
          P+G+D     L+   ++++    PE + +L AQ +F  KEL++LY
Sbjct: 57 PQGSDSSDSELELSTVRHQ----PEGLDQLQAQTKFTKKELQSLY 97


>gi|116008154 hypothetical protein LOC201229 [Homo sapiens]
          Length = 78

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 2/47 (4%)

Query: 12 LKLYKNLLYLGRDYP-KGAD-YFKKRLKNIFLKNKDVKNPEKIKELI 56
          L+LY+ LL   +  P KG   ++K  ++  F  + D  NPE+I+++I
Sbjct: 14 LQLYRYLLRCCQQLPTKGIQQHYKHAVRQSFRVHSDEDNPERIQQII 60


>gi|239787106 zinc finger protein 610 isoform b [Homo sapiens]
          Length = 419

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 12/31 (38%), Positives = 20/31 (64%)

Query: 8  RGEVLKLYKNLLYLGRDYPKGADYFKKRLKN 38
          R  +L+ Y+NL++LGR    G++   K +KN
Sbjct: 50 RDVMLENYRNLVFLGRSCVLGSNAENKPIKN 80


>gi|14150167 hypothetical protein LOC84319 [Homo sapiens]
          Length = 279

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 15/40 (37%), Positives = 20/40 (50%)

Query: 46  VKNPEKIKELIAQGEFVMKELEALYFLRKYRAMKQRYYSD 85
           V  P +IKEL+ QG   +  L+ L F   +R  K R   D
Sbjct: 210 VGTPGRIKELVKQGGLNLSPLKFLVFDWNWRDQKLRRMMD 249


>gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo
          sapiens]
          Length = 230

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 11/22 (50%), Positives = 16/22 (72%)

Query: 49 PEKIKELIAQGEFVMKELEALY 70
          PE + +L AQ +F  KEL++LY
Sbjct: 50 PEGLDQLQAQTKFTKKELQSLY 71


>gi|19718759 myoferlin isoform b [Homo sapiens]
          Length = 2048

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/30 (40%), Positives = 16/30 (53%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVKN 48
           +Y   D P+  D F + +K IF  N D KN
Sbjct: 364 IYRAEDIPQMDDAFSQTVKEIFGGNADKKN 393


>gi|7305053 myoferlin isoform a [Homo sapiens]
          Length = 2061

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/30 (40%), Positives = 16/30 (53%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVKN 48
           +Y   D P+  D F + +K IF  N D KN
Sbjct: 364 IYRAEDIPQMDDAFSQTVKEIFGGNADKKN 393


>gi|55743134 ribosomal protein S6 kinase, 90kDa, polypeptide 1
           isoform b [Homo sapiens]
          Length = 744

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVK 47
           LYL  D+ +G D F +  K +    +DVK
Sbjct: 146 LYLILDFLRGGDLFTRLSKEVMFTEEDVK 174


>gi|20149547 ribosomal protein S6 kinase, 90kDa, polypeptide 1
           isoform a [Homo sapiens]
          Length = 735

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVK 47
           LYL  D+ +G D F +  K +    +DVK
Sbjct: 137 LYLILDFLRGGDLFTRLSKEVMFTEEDVK 165


>gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Homo
           sapiens]
          Length = 740

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVK 47
           LYL  D+ +G D F +  K +    +DVK
Sbjct: 143 LYLILDFLRGGDLFTRLSKEVMFTEEDVK 171


>gi|7657526 ribosomal protein S6 kinase polypeptide 6 [Homo sapiens]
          Length = 745

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVK 47
           LYL  D+ +G D F +  K +    +DVK
Sbjct: 148 LYLILDFLRGGDVFTRLSKEVLFTEEDVK 176


>gi|55743136 ribosomal protein S6 kinase, 90kDa, polypeptide 2
           isoform b [Homo sapiens]
          Length = 741

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVK 47
           LYL  D+ +G D F +  K +    +DVK
Sbjct: 142 LYLILDFLRGGDLFTRLSKEVMFTEEDVK 170


>gi|19923570 ribosomal protein S6 kinase, 90kDa, polypeptide 2
           isoform a [Homo sapiens]
          Length = 733

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 19  LYLGRDYPKGADYFKKRLKNIFLKNKDVK 47
           LYL  D+ +G D F +  K +    +DVK
Sbjct: 134 LYLILDFLRGGDLFTRLSKEVMFTEEDVK 162


>gi|31377581 hypothetical protein LOC124989 [Homo sapiens]
          Length = 973

 Score = 25.4 bits (54), Expect = 10.0
 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)

Query: 21  LGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGEFVMKE 65
           L  D  +G     K L++ FL+N  +K+P++  E I Q +FV ++
Sbjct: 679 LAADLLEGDMIAGKNLED-FLRNVGIKSPKEEVEKILQSDFVSED 722


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,909,848
Number of Sequences: 37866
Number of extensions: 107258
Number of successful extensions: 415
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 397
Number of HSP's gapped (non-prelim): 22
length of query: 90
length of database: 18,247,518
effective HSP length: 62
effective length of query: 28
effective length of database: 15,899,826
effective search space: 445195128
effective search space used: 445195128
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 54 (25.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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