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Search of human proteins with 223005864
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
(756 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 1580 0.0
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 781 0.0
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 781 0.0
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 392 e-109
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 368 e-101
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 368 e-101
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 368 e-101
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 366 e-101
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 328 1e-89
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 251 1e-66
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 251 1e-66
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 251 1e-66
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa... 101 2e-21
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap... 101 2e-21
gi|31317224 EGF-like repeats and discoidin I-like domains-contai... 99 1e-20
gi|105990535 coagulation factor V precursor [Homo sapiens] 99 2e-20
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 90 7e-18
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 90 7e-18
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 90 7e-18
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho... 88 3e-17
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 88 3e-17
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 88 3e-17
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 88 3e-17
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 88 3e-17
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 88 3e-17
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 88 3e-17
gi|10835083 X-linked juvenile retinoschisis protein precursor [H... 86 1e-16
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa... 84 4e-16
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 81 3e-15
gi|62420886 discoidin domain receptor family, member 2 precursor... 78 3e-14
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 1580 bits (4092), Expect = 0.0
Identities = 756/756 (100%), Positives = 756/756 (100%)
Query: 1 MSRPGTATPALALVLLAVTLAGVGAQGAALEDPDYYGQEIWSREPYYARPEPELETFSPP 60
MSRPGTATPALALVLLAVTLAGVGAQGAALEDPDYYGQEIWSREPYYARPEPELETFSPP
Sbjct: 1 MSRPGTATPALALVLLAVTLAGVGAQGAALEDPDYYGQEIWSREPYYARPEPELETFSPP 60
Query: 61 LPAGPGEEWERRPQEPRPPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSEKAAN 120
LPAGPGEEWERRPQEPRPPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSEKAAN
Sbjct: 61 LPAGPGEEWERRPQEPRPPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSEKAAN 120
Query: 121 DDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFY 180
DDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFY
Sbjct: 121 DDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFY 180
Query: 181 DGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVK 240
DGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVK
Sbjct: 181 DGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVK 240
Query: 241 NGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNN 300
NGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNN
Sbjct: 241 NGSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNN 300
Query: 301 YYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISD 360
YYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISD
Sbjct: 301 YYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISD 360
Query: 361 HPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLP 420
HPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLP
Sbjct: 361 HPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLP 420
Query: 421 SLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHY 480
SLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHY
Sbjct: 421 SLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHY 480
Query: 481 IAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHT 540
IAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHT
Sbjct: 481 IAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHT 540
Query: 541 PTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYL 600
PTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYL
Sbjct: 541 PTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYL 600
Query: 601 HTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAI 660
HTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAI
Sbjct: 601 HTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAI 660
Query: 661 ISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSK 720
ISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSK
Sbjct: 661 ISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSK 720
Query: 721 TNMARIREIMEKFGKQPVSLPARRLKLRGQKRRQRG 756
TNMARIREIMEKFGKQPVSLPARRLKLRGQKRRQRG
Sbjct: 721 TNMARIREIMEKFGKQPVSLPARRLKLRGQKRRQRG 756
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 781 bits (2017), Expect = 0.0
Identities = 398/763 (52%), Positives = 510/763 (66%), Gaps = 54/763 (7%)
Query: 38 QEIWSREPYYARP--------EPELETFSPPLPAGPGEEWERRPQEPRPPKRATKPKKAP 89
+ +W P P EP ++ PPLP G+ + + P + P
Sbjct: 267 ERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQKP 326
Query: 90 KREKSAPEPPPPGKHSNKKVMRTKSSEKAAND--------DHSVRVAREDVRES------ 135
E+ E K KK + SS K D DH E++ E
Sbjct: 327 DAERQTDEE----KEELKKPKKEDSSPKEETDKWAVEKGKDHKEPRKGEELEEEWTPTEK 382
Query: 136 --CPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQ 193
CPP+G+E+ +I D Q+ AS++ R+GLGA RGRLN+Q G E+D+YDGAWCA + Q
Sbjct: 383 VKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQ 442
Query: 194 WIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSE 253
WIEVD RR TRFTGVITQGR+S D+VT++ V SNDS TWV NG +M F GN +
Sbjct: 443 WIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVD 502
Query: 254 KEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDD 313
K+ PVL+ELP P+VAR+IRI P +W NGS+CMR+E+LGC + +YY +NE+ TDD
Sbjct: 503 KDTPVLSELPEPVVARFIRIYPLTW--NGSLCMRLEVLGCSVAPVYSYY-AQNEVVATDD 559
Query: 314 LDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFH 373
LDF+HH+YK+MRQLMKVVNE CP ITR Y++GKS +GLK+YA+EISD+PGEHE+GEPEF
Sbjct: 560 LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFR 619
Query: 374 YIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEG 433
Y AG HGNEVLGRELLLLL+Q++C+EY N R+ LV++TRIH++PSLNPDGYE A +
Sbjct: 620 YTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQM 679
Query: 434 GSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENAT 493
GSE G W+LG WT +G DI +FPDLN++LW AE+R+ VP +VPN+ + IPE +LS +AT
Sbjct: 680 GSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDAT 739
Query: 494 VAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQ---------------- 537
V+ E RA+IAWMEK PFVLG NL GGE +V+YPYD+ R+P + Q
Sbjct: 740 VSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDE 799
Query: 538 --EHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLN 595
E TPD +FRWLA S+AS H +T+ R C +D+ G VNGA W+ G++N
Sbjct: 800 VSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTIN 859
Query: 596 DFSYLHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKG 655
DFSYLHTNC ELS Y+GCDK+PHES+LP EWENN+E+L+ FMEQVHRGIKG+V D G
Sbjct: 860 DFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIP 919
Query: 656 IPNAIISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCD 715
I NA ISV GINH ++TA+ GDYWR+LNPGEY VTA AEG+T S K C V YD+GAT+C+
Sbjct: 920 IANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCN 979
Query: 716 FTLSKTNMARIREIMEKFGKQPV-----SLPARRLKLRGQKRR 753
F L+++N RIREIM G +P+ S P + R Q+RR
Sbjct: 980 FILARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQRR 1022
Score = 34.7 bits (78), Expect = 0.34
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 5/61 (8%)
Query: 62 PAGPGEEWERRPQEPR-----PPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSE 116
P P E E P+ P+ PPK KPK+ P + P+ PP K K+++
Sbjct: 103 PKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATK 162
Query: 117 K 117
K
Sbjct: 163 K 163
Score = 31.2 bits (69), Expect = 3.7
Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 12/91 (13%)
Query: 51 EPELETFSPPLPAGPGEEWERRPQEPRPPKRATKPK---KAPKREKSAPEPPPPGKHSNK 107
E LE F L P E+ P P P R K + K KR +A E PP
Sbjct: 35 EEFLEGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPE------ 88
Query: 108 KVMRTKSSEKAANDDHSVRVAREDVRESCPP 138
+TK K D +V +E + S P
Sbjct: 89 ---KTKDKGKKGKKDKGPKVPKESLEGSPRP 116
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 781 bits (2016), Expect = 0.0
Identities = 377/695 (54%), Positives = 480/695 (69%), Gaps = 14/695 (2%)
Query: 62 PAGPGEEWERRPQEPRPPKRATKPKKA--PKREKSAPEPPPPGKHSNKKVMRTKSSEKAA 119
PA P E E R K KK KR+K P P + V T +
Sbjct: 48 PAQPPAETANGTSEQHVRIRVIKKKKVIMKKRKKLTLTRPTPLVTAGPLVTPTPAGTLDP 107
Query: 120 NDDHSVRVAREDVRESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDF 179
E CPPLGLE+L+++D +L AS+ + +GLG HRGRLNIQ+G+ + D
Sbjct: 108 ---------AEKQETGCPPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDL 158
Query: 180 YDGAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTV 239
YDGAWCA D W +VDA TRF+GVITQGRNS+W DWVTSYKV SNDS TW
Sbjct: 159 YDGAWCAEEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGS 218
Query: 240 KNGSG--DMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
+N S D +F NS+ E PVLN LP P VAR+IR+ PQ+W G+ C+R EIL CP+ D
Sbjct: 219 RNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSD 278
Query: 298 PNNYYHRRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVE 357
PN+ + ++D LDF+HHNYK MR+LMK V E CPNITRIY+IGKS+QGLKLY +E
Sbjct: 279 PNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVME 338
Query: 358 ISDHPGEHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIH 417
+SD PGEHE+GEPE Y+AG HGNE LGRELLLLL+QF+C E+L N R+ L+ E RIH
Sbjct: 339 MSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIH 398
Query: 418 VLPSLNPDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVP 477
+LPS+NPDGYE AY GSEL GW+ GRW + ID+N+NF DLNT LWEA+D VP VP
Sbjct: 399 LLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVP 458
Query: 478 NHYIAIPEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQ 537
NH++ +P ++ NATVA ETRAVI WM++IPFVL NL GGELVV+YP+D+ R+PW +
Sbjct: 459 NHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAAR 518
Query: 538 EHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDF 597
E TPTPDD VFRWL+ YA ++ M D RR CH++DF +NGA WHTV GS+NDF
Sbjct: 519 ELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDF 578
Query: 598 SYLHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGK-GI 656
SYLHTNCFE+++ + CDK+PHE++LP+EWENN+++L+ ++EQV GI G+VRD + GI
Sbjct: 579 SYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGI 638
Query: 657 PNAIISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDF 716
+A+I+V+GINHD+ TA GDYWRLL PG+Y+VTA AEG+ + T+NC V ++ G C+F
Sbjct: 639 ADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNF 698
Query: 717 TLSKTNMARIREIMEKFGKQPVSLPARRLKLRGQK 751
L+KT R+RE++ K P L R +LRGQK
Sbjct: 699 VLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQK 733
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 392 bits (1008), Expect = e-109
Identities = 197/433 (45%), Positives = 273/433 (63%), Gaps = 11/433 (2%)
Query: 304 RRNEMTTTDDLDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPG 363
RR + D + F++H Y E+R+ + V C I+RIY +G+S +G +L +E+SD+PG
Sbjct: 39 RRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPG 98
Query: 364 EHEVGEPEFHYIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLN 423
HE GEPEF YI HGNE +GRELL+ L Q++C EY N IV+L+ TRIH++PSLN
Sbjct: 99 VHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLN 158
Query: 424 PDGYEKAYEGGSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAI 483
PDG+EKA EL W +GR GID+N NFPDL+ +++ +++ P NH +
Sbjct: 159 PDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVY-VNEKEGGPN---NHLLKN 214
Query: 484 PEWFLSENATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTP 543
+ + +N +A ET+AVI W+ IPFVL NL GG+LV YPYD RS E++ +P
Sbjct: 215 MKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRS-GSAHEYSSSP 273
Query: 544 DDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKE--EGTVNGASWHTVAGSLNDFSYLH 601
DD +F+ LA +Y+S + M+D R C D +GT NG +W++V G + DF+YL
Sbjct: 274 DDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLS 333
Query: 602 TNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAII 661
+NCFE+++ + C+K+P E L WE+N+ SLI ++EQ+HRG+KG VRD G I NA I
Sbjct: 334 SNCFEITVELSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATI 393
Query: 662 SVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTL--- 718
SVEGI+HD+ +A DGDYWRLL PG Y +TA A G+ A TK V Y A DF L
Sbjct: 394 SVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYS-PAAGVDFELESF 452
Query: 719 SKTNMARIREIME 731
S+ E+ME
Sbjct: 453 SERKEEEKEELME 465
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 368 bits (945), Expect = e-101
Identities = 185/414 (44%), Positives = 260/414 (62%), Gaps = 18/414 (4%)
Query: 316 FKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYI 375
F HH+Y +M ++++ C ++ R Y+IG+S G +L +E S PG+HE+ EPE I
Sbjct: 48 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 107
Query: 376 AGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGS 435
HGNEV GRE+L+ L Q++C EYL N RI L+ TRIH+LPS+NPDGYE A G+
Sbjct: 108 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 167
Query: 436 ELGGWSLGRWTHDGIDINNNFPDLNTLLWE-AEDR----QNVPRKVPNHYIAIPEWFLSE 490
GW+ GR +D+N NFPDL + + AE R ++P +P HY W+
Sbjct: 168 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIP--IPQHY-----WW--- 217
Query: 491 NATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRW 550
VA ET+A++ WM+ IPFVL +L GG+LVV+YP+D + P + + +PTPD+ +F+
Sbjct: 218 -GKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKL 276
Query: 551 LAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIY 610
L+ +YA H +M D C +F K +NGA W++ G ++DF+YLHTNCFE+++
Sbjct: 277 LSRAYADVHPMMMDRSENRCGG-NFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVE 335
Query: 611 VGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHDI 670
+GC K+P E L W++N+ESL+ F+E VHRGIKG+V D GK + NA ISV+GI HDI
Sbjct: 336 LGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDI 395
Query: 671 RTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDM-GATRCDFTLSKTNM 723
TA DGDYWRLL PG ++V A+A G+ K ++ M A R DF L M
Sbjct: 396 TTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGM 449
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 368 bits (945), Expect = e-101
Identities = 185/414 (44%), Positives = 260/414 (62%), Gaps = 18/414 (4%)
Query: 316 FKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYI 375
F HH+Y +M ++++ C ++ R Y+IG+S G +L +E S PG+HE+ EPE I
Sbjct: 174 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 233
Query: 376 AGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGS 435
HGNEV GRE+L+ L Q++C EYL N RI L+ TRIH+LPS+NPDGYE A G+
Sbjct: 234 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 293
Query: 436 ELGGWSLGRWTHDGIDINNNFPDLNTLLWE-AEDR----QNVPRKVPNHYIAIPEWFLSE 490
GW+ GR +D+N NFPDL + + AE R ++P +P HY W+
Sbjct: 294 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIP--IPQHY-----WW--- 343
Query: 491 NATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRW 550
VA ET+A++ WM+ IPFVL +L GG+LVV+YP+D + P + + +PTPD+ +F+
Sbjct: 344 -GKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKL 402
Query: 551 LAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIY 610
L+ +YA H +M D C +F K +NGA W++ G ++DF+YLHTNCFE+++
Sbjct: 403 LSRAYADVHPMMMDRSENRCGG-NFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVE 461
Query: 611 VGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHDI 670
+GC K+P E L W++N+ESL+ F+E VHRGIKG+V D GK + NA ISV+GI HDI
Sbjct: 462 LGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDI 521
Query: 671 RTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDM-GATRCDFTLSKTNM 723
TA DGDYWRLL PG ++V A+A G+ K ++ M A R DF L M
Sbjct: 522 TTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGM 575
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 368 bits (945), Expect = e-101
Identities = 185/414 (44%), Positives = 260/414 (62%), Gaps = 18/414 (4%)
Query: 316 FKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYI 375
F HH+Y +M ++++ C ++ R Y+IG+S G +L +E S PG+HE+ EPE I
Sbjct: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
Query: 376 AGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGS 435
HGNEV GRE+L+ L Q++C EYL N RI L+ TRIH+LPS+NPDGYE A G+
Sbjct: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
Query: 436 ELGGWSLGRWTHDGIDINNNFPDLNTLLWE-AEDR----QNVPRKVPNHYIAIPEWFLSE 490
GW+ GR +D+N NFPDL + + AE R ++P +P HY W+
Sbjct: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIP--IPQHY-----WW--- 354
Query: 491 NATVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRW 550
VA ET+A++ WM+ IPFVL +L GG+LVV+YP+D + P + + +PTPD+ +F+
Sbjct: 355 -GKVAPETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFSPTPDEKMFKL 413
Query: 551 LAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIY 610
L+ +YA H +M D C +F K +NGA W++ G ++DF+YLHTNCFE+++
Sbjct: 414 LSRAYADVHPMMMDRSENRCGG-NFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVE 472
Query: 611 VGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHDI 670
+GC K+P E L W++N+ESL+ F+E VHRGIKG+V D GK + NA ISV+GI HDI
Sbjct: 473 LGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDI 532
Query: 671 RTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDM-GATRCDFTLSKTNM 723
TA DGDYWRLL PG ++V A+A G+ K ++ M A R DF L M
Sbjct: 533 TTAPDGDYWRLLPPGIHIVIAQAPGYAKVIKKVIIPARMKRAGRVDFILQPLGM 586
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 366 bits (940), Expect = e-101
Identities = 202/450 (44%), Positives = 275/450 (61%), Gaps = 25/450 (5%)
Query: 316 FKHHNYKEM-RQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHY 374
F+HH Y ++ R L KV NE CP ITR+Y+IG+S +G LY +E SDHPG HE EPE Y
Sbjct: 23 FRHHRYDDLVRTLYKVQNE-CPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKY 81
Query: 375 IAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGG 434
+ HGNE LGREL+L L +F+C+E+ RN RIV L+++TRIH+LPS+NPDGYE A G
Sbjct: 82 VGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQG 141
Query: 435 SELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATV 494
G+ +GR +G+D+N NFPDLNT ++ E PNH++ +P+ + S+ V
Sbjct: 142 PNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGG-----PNHHLPLPDNWKSQ---V 193
Query: 495 AAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYD-----LVRSPWKTQEHTPTPDDHVFR 549
ETRAVI WM FVL NL GG +V YPYD VR +T TPTPDD +F+
Sbjct: 194 EPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS-TPTPDDKLFQ 252
Query: 550 WLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSI 609
LA Y+ H M + D G NGASW++++ + DF+YLHTNCFE+++
Sbjct: 253 KLAKVYSYAHGWMFQGWNCGDYFPD-----GITNGASWYSLSKGMQDFNYLHTNCFEITL 307
Query: 610 YVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHD 669
+ CDK+P E +L EW NRE+LI F+EQVH+GIKG+V D + + NA+ISV GINHD
Sbjct: 308 ELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHD 367
Query: 670 IRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKT--NMARIR 727
+ + + GDY+RLL PG Y V+A A G+ T VG T +F L ++ ++ +R
Sbjct: 368 VTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVG-PAEPTLVNFHLKRSIPQVSPVR 426
Query: 728 EI-MEKFGKQPVSLPARRLKLRGQKRRQRG 756
+ G + P R K ++ QRG
Sbjct: 427 RAPSRRHGVRAKVQPQARKKEMEMRQLQRG 456
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 328 bits (841), Expect = 1e-89
Identities = 180/411 (43%), Positives = 245/411 (59%), Gaps = 39/411 (9%)
Query: 315 DFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHY 374
DF HH++ +M ++ PNITR+Y++GKS + +LY +EISD+PG HE GEPEF Y
Sbjct: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
Query: 375 IAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGG 434
I HGNEV+GRELLL L++++C+ + + + LV TRIH++PS+NPDGYEK+ EG
Sbjct: 560 IGNMHGNEVVGRELLLNLIEYLCKNF-GTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGD 618
Query: 435 SELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATV 494
S +GR + D+N NFPD F+
Sbjct: 619 SIS---VIGRNNSNNFDLNRNFPD---------------------------QFVQITDPT 648
Query: 495 AAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYS 554
ET AV++WM+ PFVL NL GG LVV YP+D T ++ +PDD VF+ +A S
Sbjct: 649 QPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQGLAT--YSKSPDDAVFQQIALS 706
Query: 555 YASTHRLMTDAR--RRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
Y+ + M R + + E F G NGASW+ V G + D++YL TNCFE++I +G
Sbjct: 707 YSKENSQMFQGRPCKNMYPNEYF--PHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELG 764
Query: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRD-SHGKGIPNAIISVEGINHDIR 671
C KYP E +LP WE NR SLI FM+QVH+G++G V D + G+GI NA ISV INH +
Sbjct: 765 CVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPVT 824
Query: 672 TANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKTN 722
T GDYWRLL PG Y +TA A G+ TKN V + GA + +FTL +++
Sbjct: 825 TYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSE-GAIQVNFTLVRSS 874
Score = 253 bits (645), Expect = 6e-67
Identities = 150/420 (35%), Positives = 220/420 (52%), Gaps = 48/420 (11%)
Query: 336 PNITRIYNIGKSHQGLKLYAVEIS-------------------DHPGEHEVGEPEFHYIA 376
P + R+++IG+S +G L+ + ++ D G G P+ +
Sbjct: 77 PGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVG 136
Query: 377 GAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGSE 436
HG+E + R++L+ L + + Y + R+V L+ T +++LPSLNPDG+E+A EG
Sbjct: 137 NMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCG 196
Query: 437 LG----GWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENA 492
G + GR G D+N +FPD + E VP
Sbjct: 197 FGDGGPSGASGRDNSRGRDLNRSFPDQFST-GEPPALDEVP------------------- 236
Query: 493 TVAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLA 552
E RA+I W+ + FVL GNL GG +V +YP+D T ++ T DD VF++LA
Sbjct: 237 ----EVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIYSKTSDDEVFKYLA 292
Query: 553 YSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
+YAS H +M ED ++G NGA W+ V G + D++Y+ NCFE+++ +
Sbjct: 293 KAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELS 352
Query: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDS-HGKGIPNAIISVEGINHDIR 671
C KYP SQL +EWENNRESLI +E+VH G+KG V+DS G G+ NA ISV GINH+I
Sbjct: 353 CCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNIT 412
Query: 672 TANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKTNMARIREIME 731
T GD++RLL PG Y +T G+ T +V + AT DF+L T + I + E
Sbjct: 413 TGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIPDTTE 472
Score = 195 bits (496), Expect = 1e-49
Identities = 122/399 (30%), Positives = 203/399 (50%), Gaps = 49/399 (12%)
Query: 316 FKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYI 375
+++H+YK++ + ++ + P+IT + N+G+S + ++++EIS+ P E EP+ ++
Sbjct: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
Query: 376 AGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGS 435
AG HGN +G ELLL L +F+C Y +N + LV+ TRI ++PSLNPDG E+A E
Sbjct: 991 AGIHGNAPVGTELLLALAEFLCLNY-KKNPAVTQLVDRTRIVIVPSLNPDGRERAQEKDC 1049
Query: 436 ELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATVA 495
+G+ G D++ +F N
Sbjct: 1050 TS---KIGQTNARGKDLDTDFT---------------------------------NNASQ 1073
Query: 496 AETRAVIA-WMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQEHTPTPDDHVFRWLAYS 554
ET+A+I ++K F L L GG ++V YPYD P +T E+ T + LA
Sbjct: 1074 PETKAIIENLIQKQDFSLSVALDGGSMLVTYPYD---KPVQTVENKET-----LKHLASL 1125
Query: 555 YASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVGCD 614
YA+ H M + + D G + GA WH+ GS+ D+S + +C E+++Y C
Sbjct: 1126 YANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSCC 1185
Query: 615 KYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISV-EGINHDIRTA 673
+P ++LP W +N+ SL+ + +VH+G+ G V+D GK I A+I + EGI ++T
Sbjct: 1186 YFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIK--VQTK 1243
Query: 674 NDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGAT 712
G + LL PG + + A A+G+ V +D ++
Sbjct: 1244 EGGYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASS 1282
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 251 bits (642), Expect = 1e-66
Identities = 138/385 (35%), Positives = 212/385 (55%), Gaps = 37/385 (9%)
Query: 314 LDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFH 373
LDF +H + M +K V + ++T +++IGKS +G L+ + + P EH +G PEF
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 374 YIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEG 433
Y+A HG+E +GRELLL L+ ++ ++ I +L+ TRIH++PS+NPDG+E +
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Query: 434 GSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENAT 493
+S+GR ++ D+N NFPD A + NV R+
Sbjct: 137 DCY---YSIGRENYNQYDLNRNFPD-------AFEYNNVSRQ------------------ 168
Query: 494 VAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDL-VRSPWKTQEHTPTPDDHVFRWLA 552
ET AV+ W++ FVL NL GG LV +YP+D V++ + TPDD VF++LA
Sbjct: 169 --PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
Query: 553 YSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
++YAS + M C + G NG SW+ + G + D++Y+ CFE+++ +
Sbjct: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINH--DI 670
C KYP E +LP W NN+ SLI +++QVH G+KG V D +G +PN I+ V+ H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPY 343
Query: 671 RTANDGDYWRLLNPGEYVVTAKAEG 695
RT G+Y+ LL PG Y++ G
Sbjct: 344 RTNKYGEYYLLLLPGSYIINVTVPG 368
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 251 bits (642), Expect = 1e-66
Identities = 138/385 (35%), Positives = 212/385 (55%), Gaps = 37/385 (9%)
Query: 314 LDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFH 373
LDF +H + M +K V + ++T +++IGKS +G L+ + + P EH +G PEF
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 374 YIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEG 433
Y+A HG+E +GRELLL L+ ++ ++ I +L+ TRIH++PS+NPDG+E +
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Query: 434 GSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENAT 493
+S+GR ++ D+N NFPD A + NV R+
Sbjct: 137 DCY---YSIGRENYNQYDLNRNFPD-------AFEYNNVSRQ------------------ 168
Query: 494 VAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDL-VRSPWKTQEHTPTPDDHVFRWLA 552
ET AV+ W++ FVL NL GG LV +YP+D V++ + TPDD VF++LA
Sbjct: 169 --PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
Query: 553 YSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
++YAS + M C + G NG SW+ + G + D++Y+ CFE+++ +
Sbjct: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINH--DI 670
C KYP E +LP W NN+ SLI +++QVH G+KG V D +G +PN I+ V+ H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPY 343
Query: 671 RTANDGDYWRLLNPGEYVVTAKAEG 695
RT G+Y+ LL PG Y++ G
Sbjct: 344 RTNKYGEYYLLLLPGSYIINVTVPG 368
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 251 bits (642), Expect = 1e-66
Identities = 138/385 (35%), Positives = 212/385 (55%), Gaps = 37/385 (9%)
Query: 314 LDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFH 373
LDF +H + M +K V + ++T +++IGKS +G L+ + + P EH +G PEF
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 374 YIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEG 433
Y+A HG+E +GRELLL L+ ++ ++ I +L+ TRIH++PS+NPDG+E +
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTSD-GKDPEITNLINSTRIHIMPSMNPDGFEAVKKP 136
Query: 434 GSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENAT 493
+S+GR ++ D+N NFPD A + NV R+
Sbjct: 137 DCY---YSIGRENYNQYDLNRNFPD-------AFEYNNVSRQ------------------ 168
Query: 494 VAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDL-VRSPWKTQEHTPTPDDHVFRWLA 552
ET AV+ W++ FVL NL GG LV +YP+D V++ + TPDD VF++LA
Sbjct: 169 --PETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLA 226
Query: 553 YSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSIYVG 612
++YAS + M C + G NG SW+ + G + D++Y+ CFE+++ +
Sbjct: 227 HTYASRNPNMKKGDE--CKNK-MNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELS 283
Query: 613 CDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINH--DI 670
C KYP E +LP W NN+ SLI +++QVH G+KG V D +G +PN I+ V+ H
Sbjct: 284 CCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPY 343
Query: 671 RTANDGDYWRLLNPGEYVVTAKAEG 695
RT G+Y+ LL PG Y++ G
Sbjct: 344 RTNKYGEYYLLLLPGSYIINVTVPG 368
>gi|10518506 coagulation factor VIII isoform b precursor [Homo
sapiens]
Length = 216
Score = 101 bits (252), Expect = 2e-21
Identities = 58/170 (34%), Positives = 88/170 (51%), Gaps = 12/170 (7%)
Query: 131 DVRESCPPLGLETLKITDFQLHASTVKRYGLGA---HRGRLNIQAGINENDFYDGAWCAG 187
D+ PLG+E+ I+D Q+ AS+ + RL++Q N AW
Sbjct: 54 DLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN-------AWRPQ 106
Query: 188 RNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMI 247
N+ ++W++VD ++ + TGV TQG SL S +V + + S D H W +
Sbjct: 107 VNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKV 166
Query: 248 FEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
F+GN + PV+N L P++ RY+RI+PQSW I +RME+LGC D
Sbjct: 167 FQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVH--QIALRMEVLGCEAQD 214
Score = 32.7 bits (73), Expect = 1.3
Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 247 IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPL 295
+F GN + N P++ARYIR++P + + +RME++GC L
Sbjct: 9 VFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDL 55
>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
Length = 2351
Score = 101 bits (252), Expect = 2e-21
Identities = 58/170 (34%), Positives = 88/170 (51%), Gaps = 12/170 (7%)
Query: 131 DVRESCPPLGLETLKITDFQLHASTVKRYGLGA---HRGRLNIQAGINENDFYDGAWCAG 187
D+ PLG+E+ I+D Q+ AS+ + RL++Q N AW
Sbjct: 2189 DLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN-------AWRPQ 2241
Query: 188 RNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMI 247
N+ ++W++VD ++ + TGV TQG SL S +V + + S D H W +
Sbjct: 2242 VNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKV 2301
Query: 248 FEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
F+GN + PV+N L P++ RY+RI+PQSW I +RME+LGC D
Sbjct: 2302 FQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVH--QIALRMEVLGCEAQD 2349
Score = 65.1 bits (157), Expect = 2e-10
Identities = 51/161 (31%), Positives = 78/161 (48%), Gaps = 16/161 (9%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHR-GRLNIQAGINENDFYDGAWCAGRNDLQQWIE 196
PLG+ + I DFQ+ AS +YG A + RL+ IN AW + WI+
Sbjct: 2043 PLGMASGHIRDFQITASG--QYGQWAPKLARLHYSGSIN-------AWST--KEPFSWIK 2091
Query: 197 VDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGD--MIFEGNSEK 254
VD G+ TQG + S +++ + +M S D W T + S M+F GN +
Sbjct: 2092 VDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDS 2151
Query: 255 EIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPL 295
N P++ARYIR++P + + +RME++GC L
Sbjct: 2152 SGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDL 2190
>gi|31317224 EGF-like repeats and discoidin I-like
domains-containing protein 3 [Homo sapiens]
Length = 480
Score = 99.4 bits (246), Expect = 1e-20
Identities = 61/165 (36%), Positives = 86/165 (52%), Gaps = 16/165 (9%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHR-----GRLNIQAGINENDFYDGAWCAGRNDLQ 192
PLG+E I++ Q+ AS+ R G + RLN + IN AW A ND
Sbjct: 161 PLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLIN-------AWTAAENDRW 213
Query: 193 QWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWV--TVKNGSGDMIFEG 250
WI+++ +R R TGVITQG + +++ SYK+ SND TW VK + DM+F G
Sbjct: 214 PWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRG 273
Query: 251 NSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPL 295
N + P N P+ A+Y+R+ PQ +RME+LGC L
Sbjct: 274 NIDNNTPYANSFTPPIKAQYVRLYPQ--VCRRHCTLRMELLGCEL 316
Score = 98.2 bits (243), Expect = 2e-20
Identities = 58/164 (35%), Positives = 88/164 (53%), Gaps = 17/164 (10%)
Query: 138 PLGLETLKITDFQLHASTVKR------YGLGAHRGRLNIQAGINENDFYDGAWCAGRNDL 191
PLG+++ I D+Q+ AS++ R + + RL+ Q +N AW +G ND
Sbjct: 322 PLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVN-------AWTSGHNDQ 374
Query: 192 QQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGS--GDMIFE 249
QW++VD T+ TG+ITQG +V SYK+ SND W ++ D +F+
Sbjct: 375 SQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQ 434
Query: 250 GNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
GN + + N + P+ AR+IRI P SW+ G I +R E+LGC
Sbjct: 435 GNFDNDTHRKNVIDPPIYARHIRILPWSWY--GRITLRSELLGC 476
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 98.6 bits (244), Expect = 2e-20
Identities = 60/171 (35%), Positives = 93/171 (54%), Gaps = 15/171 (8%)
Query: 131 DVRESCPPLGLETLKITDFQLHASTVKRYGLGAH----RGRLNIQAGINENDFYDGAWCA 186
+V PLG+E KI + Q+ AS+ K+ G + R RLN Q +N AW A
Sbjct: 2062 EVNGCSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVN-------AWQA 2114
Query: 187 GRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTW--VTVKNGSG 244
N+ +QW+E+D ++ + T +ITQG SL +V SY + S W +K+
Sbjct: 2115 KANNNKQWLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMV 2174
Query: 245 DMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPL 295
D IFEGN+ + V N P+++R+IR+ P++W N SI +R+E+ GC +
Sbjct: 2175 DKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTW--NQSIALRLELFGCDI 2223
Score = 68.2 bits (165), Expect = 3e-11
Identities = 55/167 (32%), Positives = 80/167 (47%), Gaps = 16/167 (9%)
Query: 133 RESCPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWC----AGR 188
R+ P+GL T I+D Q+ AS LG RL A +N Y+ AW A
Sbjct: 1905 RDCRMPMGLSTGIISDSQIKASEF----LGYWEPRL---ARLNNGGSYN-AWSVEKLAAE 1956
Query: 189 NDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGS--GDM 246
+ WI+VD ++ TG+ TQG S + T + V S++ W K S M
Sbjct: 1957 FASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVM 2016
Query: 247 IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
F GNS+ N+ P+VARYIRI+P ++ + +R+E+ GC
Sbjct: 2017 YFNGNSDASTIKENQFDPPIVARYIRISPTRAYNRPT--LRLELQGC 2061
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 90.1 bits (222), Expect = 7e-18
Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 139 LGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEVD 198
LG+E+ +I Q+ AS+ A R RLN + + W G + ++WI+VD
Sbjct: 279 LGMESGEIHSDQITASSQYSTNWSAERSRLN---------YPENGWTPGEDSYREWIQVD 329
Query: 199 ARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEI 256
L T V TQG S +V +YK+ VS++ W+T+K G+ ++F+GN+
Sbjct: 330 LGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTD 389
Query: 257 PVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
V+ P P++ R++RI P +W I MR E+ GC + D
Sbjct: 390 VVVAVFPKPLITRFVRIKPATW--ETGISMRFEVYGCKITD 428
Score = 50.4 bits (119), Expect = 6e-06
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 4/105 (3%)
Query: 191 LQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMI--F 248
+ +W+++D G+I QG ++ +K+ SN+ W + + S F
Sbjct: 481 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF 540
Query: 249 EGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
EGN+ + P L P + R+IRI P+ +G + +RME+LGC
Sbjct: 541 EGNNNYDTPELRTFPA-LSTRFIRIYPER-ATHGGLGLRMELLGC 583
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 90.1 bits (222), Expect = 7e-18
Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 139 LGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEVD 198
LG+E+ +I Q+ AS+ A R RLN + + W G + ++WI+VD
Sbjct: 279 LGMESGEIHSDQITASSQYSTNWSAERSRLN---------YPENGWTPGEDSYREWIQVD 329
Query: 199 ARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEI 256
L T V TQG S +V +YK+ VS++ W+T+K G+ ++F+GN+
Sbjct: 330 LGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTD 389
Query: 257 PVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
V+ P P++ R++RI P +W I MR E+ GC + D
Sbjct: 390 VVVAVFPKPLITRFVRIKPATW--ETGISMRFEVYGCKITD 428
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 191 LQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMI--F 248
+ +W+++D G+I QG ++ +K+ SN+ W + + S F
Sbjct: 481 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF 540
Query: 249 EGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDP 298
EGN+ + P L P + R+IRI P+ +G + +RME+LGC + P
Sbjct: 541 EGNNNYDTPELRTFPA-LSTRFIRIYPER-ATHGGLGLRMELLGCEVEAP 588
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 90.1 bits (222), Expect = 7e-18
Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 139 LGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEVD 198
LG+E+ +I Q+ AS+ A R RLN + + W G + ++WI+VD
Sbjct: 279 LGMESGEIHSDQITASSQYSTNWSAERSRLN---------YPENGWTPGEDSYREWIQVD 329
Query: 199 ARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKEI 256
L T V TQG S +V +YK+ VS++ W+T+K G+ ++F+GN+
Sbjct: 330 LGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGNTNPTD 389
Query: 257 PVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
V+ P P++ R++RI P +W I MR E+ GC + D
Sbjct: 390 VVVAVFPKPLITRFVRIKPATW--ETGISMRFEVYGCKITD 428
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/110 (28%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 191 LQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMI--F 248
+ +W+++D G+I QG ++ +K+ SN+ W + + S F
Sbjct: 481 INEWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSF 540
Query: 249 EGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDP 298
EGN+ + P L P + R+IRI P+ +G + +RME+LGC + P
Sbjct: 541 EGNNNYDTPELRTFPA-LSTRFIRIYPER-ATHGGLGLRMELLGCEVEAP 588
>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
sapiens]
Length = 387
Score = 87.8 bits (216), Expect = 3e-17
Identities = 59/164 (35%), Positives = 80/164 (48%), Gaps = 17/164 (10%)
Query: 138 PLGLETLKITDFQLHAST-VKRYGL-----GAHRGRLNIQAGINENDFYDGAWCAGRNDL 191
PLGL+ I D Q+ AS+ K +GL RL+ Q N AW AG
Sbjct: 233 PLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFN-------AWVAGSYGN 285
Query: 192 QQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKN--GSGDMIFE 249
QW++VD TG+ITQG + +V SYKV SNDS W ++ IF
Sbjct: 286 DQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFP 345
Query: 250 GNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
GN + N P++ARY+RI P +W + I +R+E+LGC
Sbjct: 346 GNWDNHSHKKNLFETPILARYVRILPVAW--HNRIALRLELLGC 387
Score = 70.1 bits (170), Expect = 7e-12
Identities = 52/164 (31%), Positives = 79/164 (48%), Gaps = 15/164 (9%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHR-----GRLNIQAGINENDFYDGAWCAGRNDLQ 192
PLGLE I + Q+ AS+V+ LG RLN +N AW ND
Sbjct: 73 PLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVN-------AWTPSSNDDN 125
Query: 193 QWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKN-GSGDMIFEGN 251
WI+V+ R TGV+TQG + L +++ ++KV S + H + + + F GN
Sbjct: 126 PWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGN 185
Query: 252 SEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPL 295
K +N P+ A+Y+R+ P S + + +R E+LGC L
Sbjct: 186 WNKNAVHVNLFETPVEAQYVRLYPTSC--HTACTLRFELLGCEL 227
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 87.8 bits (216), Expect = 3e-17
Identities = 51/162 (31%), Positives = 86/162 (53%), Gaps = 12/162 (7%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEV 197
PLG+E+ +I + Q+ AS+ GR Q D D W + +++++V
Sbjct: 280 PLGMESGRIANEQISASSTYS------DGRWTPQQSRLHGD--DNGWTPNLDSNKEYLQV 331
Query: 198 DARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKE 255
D R LT T + TQG S + +V SYK+ VS + W+ ++G +F+ N++
Sbjct: 332 DLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDAT 391
Query: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
VLN+L P++ R++RI PQ+W + I +R+E+ GC + D
Sbjct: 392 EVVLNKLHAPLLTRFVRIRPQTW--HSGIALRLELFGCRVTD 431
Score = 50.8 bits (120), Expect = 5e-06
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 192 QQWIEVDARRLTRFTGVITQGRN------SLWLSDWVTSYKVMVSNDSHTWVTVKNGSGD 245
++W++VD GVI QG ++ +V +KV S + W +++
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
Query: 246 M--IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
+FEGN + P + P+ A+Y+R+ P+ W G I MR+E+LGC D
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG-IGMRLEVLGCDWTD 596
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 87.8 bits (216), Expect = 3e-17
Identities = 51/162 (31%), Positives = 86/162 (53%), Gaps = 12/162 (7%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEV 197
PLG+E+ +I + Q+ AS+ GR Q D D W + +++++V
Sbjct: 280 PLGMESGRIANEQISASSTYS------DGRWTPQQSRLHGD--DNGWTPNLDSNKEYLQV 331
Query: 198 DARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKE 255
D R LT T + TQG S + +V SYK+ VS + W+ ++G +F+ N++
Sbjct: 332 DLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDAT 391
Query: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
VLN+L P++ R++RI PQ+W + I +R+E+ GC + D
Sbjct: 392 EVVLNKLHAPLLTRFVRIRPQTW--HSGIALRLELFGCRVTD 431
Score = 50.8 bits (120), Expect = 5e-06
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 192 QQWIEVDARRLTRFTGVITQGRN------SLWLSDWVTSYKVMVSNDSHTWVTVKNGSGD 245
++W++VD GVI QG ++ +V +KV S + W +++
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
Query: 246 M--IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
+FEGN + P + P+ A+Y+R+ P+ W G I MR+E+LGC D
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG-IGMRLEVLGCDWTD 596
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 87.8 bits (216), Expect = 3e-17
Identities = 51/162 (31%), Positives = 86/162 (53%), Gaps = 12/162 (7%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEV 197
PLG+E+ +I + Q+ AS+ GR Q D D W + +++++V
Sbjct: 280 PLGMESGRIANEQISASSTYS------DGRWTPQQSRLHGD--DNGWTPNLDSNKEYLQV 331
Query: 198 DARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKE 255
D R LT T + TQG S + +V SYK+ VS + W+ ++G +F+ N++
Sbjct: 332 DLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDAT 391
Query: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
VLN+L P++ R++RI PQ+W + I +R+E+ GC + D
Sbjct: 392 EVVLNKLHAPLLTRFVRIRPQTW--HSGIALRLELFGCRVTD 431
Score = 50.8 bits (120), Expect = 5e-06
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 192 QQWIEVDARRLTRFTGVITQGRN------SLWLSDWVTSYKVMVSNDSHTWVTVKNGSGD 245
++W++VD GVI QG ++ +V +KV S + W +++
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
Query: 246 M--IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
+FEGN + P + P+ A+Y+R+ P+ W G I MR+E+LGC D
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG-IGMRLEVLGCDWTD 596
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 87.8 bits (216), Expect = 3e-17
Identities = 51/162 (31%), Positives = 86/162 (53%), Gaps = 12/162 (7%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEV 197
PLG+E+ +I + Q+ AS+ GR Q D D W + +++++V
Sbjct: 280 PLGMESGRIANEQISASSTYS------DGRWTPQQSRLHGD--DNGWTPNLDSNKEYLQV 331
Query: 198 DARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKE 255
D R LT T + TQG S + +V SYK+ VS + W+ ++G +F+ N++
Sbjct: 332 DLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDAT 391
Query: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
VLN+L P++ R++RI PQ+W + I +R+E+ GC + D
Sbjct: 392 EVVLNKLHAPLLTRFVRIRPQTW--HSGIALRLELFGCRVTD 431
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 87.8 bits (216), Expect = 3e-17
Identities = 51/162 (31%), Positives = 86/162 (53%), Gaps = 12/162 (7%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEV 197
PLG+E+ +I + Q+ AS+ GR Q D D W + +++++V
Sbjct: 280 PLGMESGRIANEQISASSTYS------DGRWTPQQSRLHGD--DNGWTPNLDSNKEYLQV 331
Query: 198 DARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKE 255
D R LT T + TQG S + +V SYK+ VS + W+ ++G +F+ N++
Sbjct: 332 DLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDAT 391
Query: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
VLN+L P++ R++RI PQ+W + I +R+E+ GC + D
Sbjct: 392 EVVLNKLHAPLLTRFVRIRPQTW--HSGIALRLELFGCRVTD 431
Score = 50.8 bits (120), Expect = 5e-06
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 192 QQWIEVDARRLTRFTGVITQGRN------SLWLSDWVTSYKVMVSNDSHTWVTVKNGSGD 245
++W++VD GVI QG ++ +V +KV S + W +++
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
Query: 246 M--IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
+FEGN + P + P+ A+Y+R+ P+ W G I MR+E+LGC D
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG-IGMRLEVLGCDWTD 596
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 87.8 bits (216), Expect = 3e-17
Identities = 51/162 (31%), Positives = 86/162 (53%), Gaps = 12/162 (7%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQWIEV 197
PLG+E+ +I + Q+ AS+ GR Q D D W + +++++V
Sbjct: 280 PLGMESGRIANEQISASSTYS------DGRWTPQQSRLHGD--DNGWTPNLDSNKEYLQV 331
Query: 198 DARRLTRFTGVITQGRNSLWLSD--WVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSEKE 255
D R LT T + TQG S + +V SYK+ VS + W+ ++G +F+ N++
Sbjct: 332 DLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDAT 391
Query: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
VLN+L P++ R++RI PQ+W + I +R+E+ GC + D
Sbjct: 392 EVVLNKLHAPLLTRFVRIRPQTW--HSGIALRLELFGCRVTD 431
Score = 50.8 bits (120), Expect = 5e-06
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 192 QQWIEVDARRLTRFTGVITQGRN------SLWLSDWVTSYKVMVSNDSHTWVTVKNGSGD 245
++W++VD GVI QG ++ +V +KV S + W +++
Sbjct: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
Query: 246 M--IFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPD 297
+FEGN + P + P+ A+Y+R+ P+ W G I MR+E+LGC D
Sbjct: 545 QPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG-IGMRLEVLGCDWTD 596
>gi|10835083 X-linked juvenile retinoschisis protein precursor [Homo
sapiens]
Length = 224
Score = 85.9 bits (211), Expect = 1e-16
Identities = 54/173 (31%), Positives = 90/173 (52%), Gaps = 21/173 (12%)
Query: 131 DVRESCP---PLGLETLKITDFQLHASTVKRY-----GLGAHRGRLNIQAGINENDFYDG 182
D CP PLG E+ ++T Q+ S ++Y A++ RLN Q +
Sbjct: 58 DCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQG-------FGC 110
Query: 183 AWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSH-TWVTVKN 241
AW + D QW+++D + + +G++TQGR + +W+T Y V D W+ K+
Sbjct: 111 AWLSKFQDSSQWLQIDLKEIKVISGILTQGRCD--IDEWMTKYSVQYRTDERLNWIYYKD 168
Query: 242 GSG-DMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
+G + +F GNS++ V N L P+++R+IR+ P W + I +RME+L C
Sbjct: 169 QTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGW--HVRIAIRMELLEC 219
>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
sapiens]
Length = 775
Score = 84.3 bits (207), Expect = 4e-16
Identities = 51/158 (32%), Positives = 81/158 (51%), Gaps = 7/158 (4%)
Query: 139 LGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGA-WCAGRNDLQQWIEV 197
LG+E+ I D Q+ AS+V + H G+ N G W A D QW+++
Sbjct: 296 LGMESGVIADPQITASSVLEWT--DHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQI 353
Query: 198 DARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNG--SGDMIFEGNSEKE 255
D + + TG+IT G + + +V++Y+++ S+D W + D IF+GN +
Sbjct: 354 DLNKEKKITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYH 413
Query: 256 IPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
V N P++AR+IR+NP W I M+ME+LGC
Sbjct: 414 QDVRNNFLPPIIARFIRVNPTQW--QQKIAMKMELLGC 449
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
sapiens]
Length = 1331
Score = 81.3 bits (199), Expect = 3e-15
Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 182 GAWCAGRNDLQQWIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKN 241
G W +D QW++VD + + + TQGR S SDWVT Y+++ S+ W
Sbjct: 72 GGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSS--SDWVTQYRMLYSDTGRNWKPYHQ 129
Query: 242 GSGDMIFEGNSEKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
F GN + V +EL P++ARY+RI P W G I +R+E+ GC
Sbjct: 130 DGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGC 181
>gi|62420886 discoidin domain receptor family, member 2 precursor
[Homo sapiens]
Length = 855
Score = 78.2 bits (191), Expect = 3e-14
Identities = 51/161 (31%), Positives = 84/161 (52%), Gaps = 13/161 (8%)
Query: 138 PLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWC----AGRNDLQQ 193
PLG+ +I D + AS+ A GRL+ + G DGAWC +DL++
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEG-------DGAWCPEIPVEPDDLKE 85
Query: 194 WIEVDARRLTRFTGVITQGRNSLWLS-DWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNS 252
++++D L T V TQGR++ ++ YK+ S D W++ +N G + +GNS
Sbjct: 86 FLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNS 145
Query: 253 EKEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGC 293
L +L P+VAR++R P + + ++CMR+E+ GC
Sbjct: 146 NPYDIFLKDLEPPIVARFVRFIPVT-DHSMNVCMRVELYGC 185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,492,129
Number of Sequences: 37866
Number of extensions: 1779654
Number of successful extensions: 11531
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 9476
Number of HSP's gapped (non-prelim): 1764
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.