Guide to the Human Genome
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Search of human proteins with 22218355

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22218355 WAP four-disulfide core domain 11 precursor [Homo
sapiens]
         (87 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22218355 WAP four-disulfide core domain 11 precursor [Homo sa...   197   2e-51
gi|22218351 protease inhibitor WAP9 [Homo sapiens]                     69   6e-13
gi|21703706 WAP four-disulfide core domain 10A precursor [Homo s...    44   4e-05
gi|26006869 WAP four-disulfide core domain 10B isoform a precurs...    43   6e-05
gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo s...    37   0.004
gi|25188181 WAP four-disulfide core domain 13 precursor [Homo sa...    33   0.037
gi|5174445 lanthionine synthetase C-like protein 1 [Homo sapiens]      29   0.91 
gi|212274477 lanthionine synthetase C-like protein 1 [Homo sapiens]    29   0.91 
gi|212274337 lanthionine synthetase C-like protein 1 [Homo sapiens]    29   0.91 
gi|7657319 ADAM-like, decysin 1 isoform 1 [Homo sapiens]               29   0.91 
gi|223671932 ADAM-like, decysin 1 isoform 2 [Homo sapiens]             29   0.91 
gi|223671930 ADAM-like, decysin 1 isoform 2 [Homo sapiens]             29   0.91 
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]            28   1.2  
gi|169213798 PREDICTED: zinc finger protein 728 [Homo sapiens]         28   2.0  
gi|169214227 PREDICTED: zinc finger protein 728 [Homo sapiens]         28   2.0  
gi|169213571 PREDICTED: zinc finger protein 728 [Homo sapiens]         28   2.0  
gi|114326453 a disintegrin and metalloproteinase domain 7 [Homo ...    28   2.0  
gi|239747141 PREDICTED: hypothetical protein XP_002343923 [Homo ...    27   3.5  
gi|190014599 zinc finger protein 717 [Homo sapiens]                    27   3.5  
gi|66346695 fibrillin 2 precursor [Homo sapiens]                       27   4.5  
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]                27   4.5  
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]      26   5.9  
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]      26   5.9  
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]      26   5.9  
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]                26   5.9  
gi|33188443 microfilament and actin filament cross-linker protei...    26   7.7  

>gi|22218355 WAP four-disulfide core domain 11 precursor [Homo
          sapiens]
          Length = 87

 Score =  197 bits (500), Expect = 2e-51
 Identities = 87/87 (100%), Positives = 87/87 (100%)

Query: 1  MVSLMKLWIPMLMTFFCTVLLSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFR 60
          MVSLMKLWIPMLMTFFCTVLLSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFR
Sbjct: 1  MVSLMKLWIPMLMTFFCTVLLSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFR 60

Query: 61 CKDKNYTCCWTYCGNICWINVETSGDY 87
          CKDKNYTCCWTYCGNICWINVETSGDY
Sbjct: 61 CKDKNYTCCWTYCGNICWINVETSGDY 87


>gi|22218351 protease inhibitor WAP9 [Homo sapiens]
          Length = 89

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 36/81 (44%), Positives = 44/81 (54%), Gaps = 3/81 (3%)

Query: 5  MKLWIPMLMTFFCTV--LLSVLGEM-RKKRYDRKELLLEECWGKPNVKECTNKCSKAFRC 61
          MK WI +L+ F   V  LL VLG    K  +       E+CW +P  K C  +C+K   C
Sbjct: 1  MKPWILLLVMFISGVVMLLPVLGSFWNKDPFLDMIRETEQCWVQPPYKYCEKRCTKIMTC 60

Query: 62 KDKNYTCCWTYCGNICWINVE 82
             N+TCCWTYCGNIC  N E
Sbjct: 61 VRPNHTCCWTYCGNICLDNEE 81


>gi|21703706 WAP four-disulfide core domain 10A precursor [Homo
          sapiens]
          Length = 79

 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 6/72 (8%)

Query: 9  IPMLMTFFCTVLLSVLGEMRKKRYDRKELLLEE---CWGKPNVKECTNKCSKAFRCKDKN 65
          +P+L+   C +LL   G  R K+  +K  L  E   C  +P +  C + C     C+  N
Sbjct: 7  LPVLV--LCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDCQANN 64

Query: 66 YTCCWTYCGNIC 77
            CC TYCGN+C
Sbjct: 65 I-CCSTYCGNVC 75


>gi|26006869 WAP four-disulfide core domain 10B isoform a
          precursor [Homo sapiens]
          Length = 73

 Score = 42.7 bits (99), Expect = 6e-05
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 4/67 (5%)

Query: 11 MLMTFFCTVLLSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFRCKDKNYTCCW 70
          +L+   C +LL   G  R K   ++   ++ C  +P++  C + CS   +C + N  CC 
Sbjct: 7  LLVLVLCVLLLQAQGGYRDKMRMQR---IKVCEKRPSIDLCIHHCSYFQKC-ETNKICCS 62

Query: 71 TYCGNIC 77
           +CGNIC
Sbjct: 63 AFCGNIC 69


>gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo
          sapiens]
          Length = 89

 Score = 36.6 bits (83), Expect = 0.004
 Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 1/39 (2%)

Query: 39 LEECWGKPNVKECTNKCSKAFRCKDKNYTCCWTYCGNIC 77
          ++ C  +P++  C + CS   +C + N  CC  +CGNIC
Sbjct: 48 IKVCEKRPSIDLCIHHCSYFQKC-ETNKICCSAFCGNIC 85


>gi|25188181 WAP four-disulfide core domain 13 precursor [Homo
          sapiens]
          Length = 93

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 5  MKLWIPM-LMTFFCTVLLSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFRCKD 63
          MK  +P+  +  FC  L  V G   K+R  +  L    C   P  + CT+ C+    C +
Sbjct: 1  MKPVLPLQFLVVFCLALQLVPGSP-KQRVLKYILEPPPCISAP--ENCTHLCTMQEDC-E 56

Query: 64 KNYTCCWTYCGNIC 77
          K + CC ++CG +C
Sbjct: 57 KGFQCCSSFCGIVC 70


>gi|5174445 lanthionine synthetase C-like protein 1 [Homo sapiens]
          Length = 399

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 33  DRKELLLEECWGKPNVKECTNKCSKAFRCKDKNYTCCWTYCGNICW 78
           D ++LL+  C G P V     +  K FR  ++ Y C    C ++ W
Sbjct: 267 DNRDLLVHWCHGAPGVIYMLIQAYKVFR--EEKYLCDAYQCADVIW 310


>gi|212274477 lanthionine synthetase C-like protein 1 [Homo sapiens]
          Length = 399

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 33  DRKELLLEECWGKPNVKECTNKCSKAFRCKDKNYTCCWTYCGNICW 78
           D ++LL+  C G P V     +  K FR  ++ Y C    C ++ W
Sbjct: 267 DNRDLLVHWCHGAPGVIYMLIQAYKVFR--EEKYLCDAYQCADVIW 310


>gi|212274337 lanthionine synthetase C-like protein 1 [Homo sapiens]
          Length = 399

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 33  DRKELLLEECWGKPNVKECTNKCSKAFRCKDKNYTCCWTYCGNICW 78
           D ++LL+  C G P V     +  K FR  ++ Y C    C ++ W
Sbjct: 267 DNRDLLVHWCHGAPGVIYMLIQAYKVFR--EEKYLCDAYQCADVIW 310


>gi|7657319 ADAM-like, decysin 1 isoform 1 [Homo sapiens]
          Length = 470

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)

Query: 40  EEC-WGKPNVKECTNKCSKAFRCKDKNYTCC 69
           E+C  G P  KECTN C +A  CK K  T C
Sbjct: 432 EDCDCGSP--KECTNLCCEALTCKLKPGTDC 460


>gi|223671932 ADAM-like, decysin 1 isoform 2 [Homo sapiens]
          Length = 391

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)

Query: 40  EEC-WGKPNVKECTNKCSKAFRCKDKNYTCC 69
           E+C  G P  KECTN C +A  CK K  T C
Sbjct: 353 EDCDCGSP--KECTNLCCEALTCKLKPGTDC 381


>gi|223671930 ADAM-like, decysin 1 isoform 2 [Homo sapiens]
          Length = 391

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)

Query: 40  EEC-WGKPNVKECTNKCSKAFRCKDKNYTCC 69
           E+C  G P  KECTN C +A  CK K  T C
Sbjct: 353 EDCDCGSP--KECTNLCCEALTCKLKPGTDC 381


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 14/38 (36%), Positives = 17/38 (44%), Gaps = 4/38 (10%)

Query: 40  EECWGKPNVKECTNKCSKAFRCKDKNYTCCWTYCGNIC 77
           E+C     V+ C   CS+  RCKD    C   Y G  C
Sbjct: 304 EDC----GVRSCPRGCSQRGRCKDGRCVCDPGYTGEDC 337



 Score = 26.2 bits (56), Expect = 5.9
 Identities = 10/30 (33%), Positives = 14/30 (46%)

Query: 48  VKECTNKCSKAFRCKDKNYTCCWTYCGNIC 77
           V+ C   C++  RC+D    C   Y G  C
Sbjct: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDC 430


>gi|169213798 PREDICTED: zinc finger protein 728 [Homo sapiens]
          Length = 687

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)

Query: 21  LSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFRC 61
           +SVL + +K    +K    EEC GKP   E   +C K F C
Sbjct: 576 VSVLNKHKKIHAGKKFYKCEECGGKPYKCE---ECGKFFNC 613


>gi|169214227 PREDICTED: zinc finger protein 728 [Homo sapiens]
          Length = 687

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)

Query: 21  LSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFRC 61
           +SVL + +K    +K    EEC GKP   E   +C K F C
Sbjct: 576 VSVLNKHKKIHAGKKFYKCEECGGKPYKCE---ECGKFFNC 613


>gi|169213571 PREDICTED: zinc finger protein 728 [Homo sapiens]
          Length = 687

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)

Query: 21  LSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFRC 61
           +SVL + +K    +K    EEC GKP   E   +C K F C
Sbjct: 576 VSVLNKHKKIHAGKKFYKCEECGGKPYKCE---ECGKFFNC 613


>gi|114326453 a disintegrin and metalloproteinase domain 7 [Homo
           sapiens]
          Length = 754

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 17/41 (41%), Positives = 19/41 (46%), Gaps = 2/41 (4%)

Query: 40  EECWGKPNVKECTNKCSKAFRCKDK-NYTCCWTYCGNICWI 79
           EEC   P  +ECTN C  A  C  K  +TC    C   C I
Sbjct: 414 EECDCGP-AQECTNPCCDAHTCVLKPGFTCAEGECCESCQI 453


>gi|239747141 PREDICTED: hypothetical protein XP_002343923 [Homo
           sapiens]
          Length = 904

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 3/35 (8%)

Query: 30  KRYDRKELLLEECWGKPNVK--ECTNKCSKAFRCK 62
           K + RK  L    W     K  EC N+C K FRCK
Sbjct: 479 KTFHRKSFLTIHQWTHTGEKPYEC-NECGKTFRCK 512


>gi|190014599 zinc finger protein 717 [Homo sapiens]
          Length = 914

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 3/35 (8%)

Query: 30  KRYDRKELLLEECWGKPNVK--ECTNKCSKAFRCK 62
           K + RK  L    W     K  EC N+C K FRCK
Sbjct: 486 KTFHRKSFLTIHQWTHTGEKPYEC-NECGKTFRCK 519


>gi|66346695 fibrillin 2 precursor [Homo sapiens]
          Length = 2912

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 9/34 (26%), Positives = 16/34 (47%)

Query: 44  GKPNVKECTNKCSKAFRCKDKNYTCCWTYCGNIC 77
           G  ++++C+ +C     C D +  C   Y G  C
Sbjct: 142 GSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYC 175


>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
          Length = 2699

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 2/42 (4%)

Query: 40  EECWGKP--NVKECTNKCSKAFRCKDKNYTCCWTYCGNICWI 79
           EE W  P  N + C  +C++   CKD    C   + G  C I
Sbjct: 699 EEGWTGPACNQRACHPRCAEHGTCKDGKCECSQGWNGEHCTI 740


>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
          Length = 2725

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 40  EECWGKPNVKE--CTNKCSKAFRCKDKNYTCCWTYCGNICWI 79
           EE W  P  +E  C + C++  +CKD    C   + G+ C I
Sbjct: 713 EEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTI 754


>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
          Length = 2731

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 40  EECWGKPNVKE--CTNKCSKAFRCKDKNYTCCWTYCGNICWI 79
           EE W  P  +E  C + C++  +CKD    C   + G+ C I
Sbjct: 712 EEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTI 753


>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
          Length = 2732

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 40  EECWGKPNVKE--CTNKCSKAFRCKDKNYTCCWTYCGNICWI 79
           EE W  P  +E  C + C++  +CKD    C   + G+ C I
Sbjct: 713 EEGWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTI 754


>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
          Length = 3144

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 11/34 (32%), Positives = 18/34 (52%), Gaps = 4/34 (11%)

Query: 53  NKCSKAFRCKDK----NYTCCWTYCGNICWINVE 82
           N+C     CKD+      +C  +Y G +C +NV+
Sbjct: 573 NECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVD 606


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 10/33 (30%), Positives = 18/33 (54%)

Query: 34   RKELLLEECWGKPNVKECTNKCSKAFRCKDKNY 66
            R+E   ++ W     KE  ++ S +  CK+K+Y
Sbjct: 1581 RQETNYQDSWVTSKTKETKHQISSSNECKEKSY 1613


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.499 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,515,430
Number of Sequences: 37866
Number of extensions: 138836
Number of successful extensions: 530
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 505
Number of HSP's gapped (non-prelim): 41
length of query: 87
length of database: 18,247,518
effective HSP length: 59
effective length of query: 28
effective length of database: 16,013,424
effective search space: 448375872
effective search space used: 448375872
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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