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Search of human proteins with 221316749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
(417 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 862 0.0
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 447 e-125
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 354 9e-98
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 330 2e-90
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 302 4e-82
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 300 2e-81
gi|27436871 carboxypeptidase O [Homo sapiens] 293 2e-79
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 293 2e-79
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 288 6e-78
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 288 6e-78
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 230 2e-60
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 206 4e-53
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 145 9e-35
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 47 3e-05
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 44 3e-04
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 41 0.002
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 35 0.13
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 35 0.13
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 35 0.13
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 35 0.16
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 35 0.16
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 35 0.16
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 35 0.16
gi|46409372 G protein-coupled receptor 153 [Homo sapiens] 33 0.63
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 32 0.82
gi|55770834 centromere protein F [Homo sapiens] 32 1.4
gi|4505379 nuclear factor erythroid 2-like 1 [Homo sapiens] 31 1.8
gi|118600961 akt substrate AS250 [Homo sapiens] 31 1.8
gi|27734781 melanoma antigen family B, 18 [Homo sapiens] 31 2.4
gi|145386551 SH3 domain and tetratricopeptide repeats 1 [Homo sa... 30 3.1
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 862 bits (2228), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV 60
MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV
Sbjct: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV 60
Query: 61 AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYN 120
AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYN
Sbjct: 61 AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYN 120
Query: 121 NWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREW 180
NWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREW
Sbjct: 121 NWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREW 180
Query: 181 VSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKN 240
VSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKN
Sbjct: 181 VSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKN 240
Query: 241 QNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVY 300
QNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVY
Sbjct: 241 QNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVY 300
Query: 301 ITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISG 360
ITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISG
Sbjct: 301 ITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISG 360
Query: 361 SSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS 417
SSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS
Sbjct: 361 SSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS 417
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 447 bits (1149), Expect = e-125
Identities = 204/412 (49%), Positives = 291/412 (70%), Gaps = 6/412 (1%)
Query: 9 LIATTLAIAPVR-----FDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAAN 63
L+ T+A+A F+ EKVFRV +DE +II++LA T ++DFW P + + +
Sbjct: 5 LVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPH 64
Query: 64 MMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWE 123
VDFRV +++ +++ L QN++ Y++LI +L+ +E QFD + G HSY KYN WE
Sbjct: 65 STVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATG-HSYEKYNKWE 123
Query: 124 KIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSP 183
I AWT+++ + P ++SR IG+T E +Y+LK+G+ + + AIF DCG HAREW+SP
Sbjct: 124 TIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISP 183
Query: 184 AFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNS 243
AFCQWFV +A +TYGR +T+LLD+++FY+LPV N+DGYI++WTK+R WRK RS + S
Sbjct: 184 AFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGS 243
Query: 244 KCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITF 303
CIGTD NRNF+A W I + +PC + Y G A ESEKETKA+ +FIR+ L+ IK Y+T
Sbjct: 244 SCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTI 303
Query: 304 HSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSL 363
HSYSQM+++PY Y KL N+ +L +AK L++ + T+Y YGP +TIYP +G S
Sbjct: 304 HSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSD 363
Query: 364 DWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKH 415
DWAYD GI+++F FELRD G++GFLLPES+I+ TC ET LA+K++A Y+L+H
Sbjct: 364 DWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEH 415
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 354 bits (908), Expect = 9e-98
Identities = 170/399 (42%), Positives = 244/399 (61%), Gaps = 4/399 (1%)
Query: 20 RFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQ 79
R+ +KV R P+ E++A +K ++ ++D W P + +V+ + D + + S+A+
Sbjct: 36 RYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALL 95
Query: 80 SALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGR----HSYAKYNNWEKIVAWTEKMMDK 135
+ L + + Y++LI DLQ+ +EK + R ++Y Y++ E+I W +
Sbjct: 96 AFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKT 155
Query: 136 YPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATK 195
+ ++ IG + E L++LK+G ++ ++A++ DCGIHAREW+ PAFCQWFV +A
Sbjct: 156 HSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALL 215
Query: 196 TYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFN 255
TY + M K+L+ + FYI+PVFNVDGY +SWT +R WRK RS+N +C G D NRN+
Sbjct: 216 TYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWK 275
Query: 256 ASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYG 315
W + PC D Y G PESE E KAV NF+R H I+ Y++FH+Y+QMLL+PY
Sbjct: 276 VKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYS 335
Query: 316 YTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTF 375
Y PN + A + L + Y RY YGP +T+Y SGSS+DWAY GI + F
Sbjct: 336 YKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAF 395
Query: 376 AFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILK 414
AFELRD G FGFLLPE IKPTC ETMLAVK I ++LK
Sbjct: 396 AFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 434
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 330 bits (845), Expect = 2e-90
Identities = 171/421 (40%), Positives = 255/421 (60%), Gaps = 10/421 (2%)
Query: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV 60
+ +++P+ L A F +V P+ +Q ++++L T E+ W P +
Sbjct: 6 LAVLVPIVLFCEQHVFA---FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLI 62
Query: 61 AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHS---YA 117
V F V+ + +++ L+ + + +L+ D+++ I++Q + + R S Y
Sbjct: 63 VKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQIS-NDTVSPRASASYYE 121
Query: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRK-AIFTDCGIH 176
+Y++ +I +W E + +++P+M+++I IGS+ E PLYVLK+ K + K AI+ DCGIH
Sbjct: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181
Query: 177 AREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKN 236
AREW+SPAFC WF+ T+ YG T LL ++FY++PV NVDGY +SW KNRMWRKN
Sbjct: 182 AREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKN 241
Query: 237 RSKNQNSKCIGTDLNRNF-NASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLN 295
RS N+ CIGTDLNRNF + W ++ C++ Y G PESE E KAV +F+R ++N
Sbjct: 242 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 301
Query: 296 EIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVL-STRYETRYIYGPIEST 354
+IK YI+ HSYSQ ++FPY YT +HE+L+ VA + T TRY +G T
Sbjct: 302 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 361
Query: 355 IYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILK 414
+Y G DW YDLGIK++F ELRD G +GFLLPE IKPTCRE AV IA ++++
Sbjct: 362 LYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421
Query: 415 H 415
+
Sbjct: 422 N 422
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 302 bits (773), Expect = 4e-82
Identities = 164/426 (38%), Positives = 254/426 (59%), Gaps = 22/426 (5%)
Query: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTN--ELDFWY----P 54
MRLIL G + + F ++V + P +E+Q + L +LDFW P
Sbjct: 3 MRLILFFGALFGHIYCLET-FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP 61
Query: 55 GATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQ-----FDVKED 109
G T HV RV QA++ L+ + Y I+I D+Q ++K+ F+ + +
Sbjct: 62 GETAHV--------RVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRE 113
Query: 110 IPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAI 169
G ++ Y+ E+I + ++ ++P +VS++ IGS+ E+ P+ VLK ++ AI
Sbjct: 114 RSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAI 172
Query: 170 FTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTK 229
+ D GIHAREWV+ A W + YG++ +T +LD ++ ++LPV N DGY++S TK
Sbjct: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 232
Query: 230 NRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNF 289
NRMWRK RSK S C+G D NRN++A + +++PC+D+Y G + SE E K++ +F
Sbjct: 233 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 292
Query: 290 IRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYG 349
I+SH ++K +IT HSYSQ+L+FPYGY + ++L++VA+ L + + T+Y G
Sbjct: 293 IKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVG 351
Query: 350 PIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIA 409
PI S IY SG S+DW+YD GIK++FAFELRD G++GFLLP +I PT ET L +K I
Sbjct: 352 PICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIM 411
Query: 410 KYILKH 415
+++ H
Sbjct: 412 EHVRDH 417
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 300 bits (767), Expect = 2e-81
Identities = 160/421 (38%), Positives = 247/421 (58%), Gaps = 14/421 (3%)
Query: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTN--ELDFWYPGATH 58
MR IL +G + + +F ++V R+ ++ + + L +N +L+FW ++
Sbjct: 1 MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF 60
Query: 59 HVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRH---- 114
N VD V QA +S L + Y + I DLQ ++ + D + G+
Sbjct: 61 ----NRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSN 116
Query: 115 --SYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGE-KNERRKAIFT 171
+Y Y++ E I + + +P++ R+KIG + E+ P+YVLK K RR A++
Sbjct: 117 NFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWL 176
Query: 172 DCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNR 231
+ GIH+REW+S A W + Y R+ +T +L++M+ ++LPV N DGY+++ T+NR
Sbjct: 177 NAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNR 236
Query: 232 MWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIR 291
+WRK RS+N S CIG D NRN+NAS+ +++PC++ Y G SE E K+V +FI+
Sbjct: 237 LWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQ 296
Query: 292 SHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPI 351
H N K +I HSYSQ+L++PYGY+ K P+ E+L KVA++ L++ T Y GP
Sbjct: 297 KHGN-FKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPT 355
Query: 352 ESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKY 411
+T+YP SGSS+DWAYD GIK F FELRD G +GFLLP ++I PT ET L +K I ++
Sbjct: 356 CTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEH 415
Query: 412 I 412
+
Sbjct: 416 V 416
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 293 bits (751), Expect = 2e-79
Identities = 137/293 (46%), Positives = 195/293 (66%), Gaps = 1/293 (0%)
Query: 114 HSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNER-RKAIFTD 172
+SY Y+ +I W ++ +KY E+V++ +G T E +P+Y LKI + + +K I+ D
Sbjct: 45 YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMD 104
Query: 173 CGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRM 232
CGIHAREW++PAFCQWFV + + + N + KLL ++FY+LPV N+DGYI++WT +R+
Sbjct: 105 CGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL 164
Query: 233 WRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRS 292
WRK+RS + N C GTDLNRNFNASW SI + + + G+ P SE ETKAV +FI S
Sbjct: 165 WRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224
Query: 293 HLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIE 352
++I ++T HSY Q++L PYGYT NH ++ +V + + L +Y T Y G
Sbjct: 225 KKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSA 284
Query: 353 STIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAV 405
+Y SGSS DWA D+GI ++ FELRD G +GF+LPE++I+PTC ETM AV
Sbjct: 285 DILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAV 337
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 293 bits (750), Expect = 2e-79
Identities = 155/403 (38%), Positives = 241/403 (59%), Gaps = 13/403 (3%)
Query: 21 FDREKVFRVKPQDEKQADIIKDLAKTN--ELDFWYPGATHHVAANMMVDFRVSEKESQAI 78
F +V R+ DE Q +K+L +LDFW G H +D RV QA+
Sbjct: 20 FVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWR-GPAH---PGSPIDVRVPFPSIQAV 75
Query: 79 QSALDQNKMHYEILIHDLQ----EEIEKQFDVKEDIPGRHS--YAKYNNWEKIVAWTEKM 132
+ L+ + + YE +I D+Q EE E+ F + + YA Y+ E+I + + +
Sbjct: 76 KIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLL 135
Query: 133 MDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQ 192
+ + P +VS+I+IG+T E P+YVLK +R AI+ D GIH+REWV+ A WF +
Sbjct: 136 VAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKK 195
Query: 193 ATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNR 252
T+ YG++ T +LD ++ ++ V N DG+ ++ + NRMWRK RS S CIG D NR
Sbjct: 196 ITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNR 255
Query: 253 NFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLF 312
N++A + +++PC++ Y G SE E K++ +F++ H N IK +I+ HSYSQ+L++
Sbjct: 256 NWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSYSQLLMY 314
Query: 313 PYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIK 372
PYGY ++ P+ ++L +++K L++ Y T++ YG I IY SGS++DW Y GIK
Sbjct: 315 PYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIK 374
Query: 373 HTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKH 415
++F FELRD G++GFLLP S+I PT +ET LA+ I ++ L H
Sbjct: 375 YSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNH 417
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 288 bits (737), Expect = 6e-78
Identities = 149/409 (36%), Positives = 245/409 (59%), Gaps = 13/409 (3%)
Query: 15 AIAPVRFDREKVFRVKPQDEKQADIIKDLA--KTNELDFWYPGATHHVAANMMVDFRVSE 72
A+ + F ++V RV +DEKQ ++ DL K ++DFW A ++ VD RV
Sbjct: 31 ALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPAR----PSLPVDMRVPF 86
Query: 73 KESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVK------EDIPGRHSYAKYNNWEKIV 126
E + I++ L+ + + Y I+I D+Q ++++ E SY+ Y+ E+I
Sbjct: 87 SELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIY 146
Query: 127 AWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFC 186
+W + + ++ ++VS+I+IG++ E+ + VLK R AI+ D GIH+REW++ A
Sbjct: 147 SWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATG 206
Query: 187 QWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCI 246
W + YG+++++T +L+ M+ +I V N DG+ ++ + NR+WRKN+S CI
Sbjct: 207 IWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCI 266
Query: 247 GTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSY 306
G DLNRN+ + + + ++PC++ Y G +P+SE E A+ NFI +H N K I+ HSY
Sbjct: 267 GVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSY 325
Query: 307 SQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWA 366
SQML++PYG + N +L +AK + L + YI+G I +T+Y SG ++DWA
Sbjct: 326 SQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVASGITVDWA 385
Query: 367 YDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKH 415
YD GIK+ F+FELRD G++GFLLP ++I PT +ET +A++ I ++ L H
Sbjct: 386 YDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNH 434
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 288 bits (737), Expect = 6e-78
Identities = 149/409 (36%), Positives = 245/409 (59%), Gaps = 13/409 (3%)
Query: 15 AIAPVRFDREKVFRVKPQDEKQADIIKDLA--KTNELDFWYPGATHHVAANMMVDFRVSE 72
A+ + F ++V RV +DEKQ ++ DL K ++DFW A ++ VD RV
Sbjct: 31 ALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPAR----PSLPVDMRVPF 86
Query: 73 KESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVK------EDIPGRHSYAKYNNWEKIV 126
E + I++ L+ + + Y I+I D+Q ++++ E SY+ Y+ E+I
Sbjct: 87 SELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIY 146
Query: 127 AWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFC 186
+W + + ++ ++VS+I+IG++ E+ + VLK R AI+ D GIH+REW++ A
Sbjct: 147 SWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATG 206
Query: 187 QWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCI 246
W + YG+++++T +L+ M+ +I V N DG+ ++ + NR+WRKN+S CI
Sbjct: 207 IWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCI 266
Query: 247 GTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSY 306
G DLNRN+ + + + ++PC++ Y G +P+SE E A+ NFI +H N K I+ HSY
Sbjct: 267 GVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSY 325
Query: 307 SQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWA 366
SQML++PYG + N +L +AK + L + YI+G I +T+Y SG ++DWA
Sbjct: 326 SQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVASGITVDWA 385
Query: 367 YDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKH 415
YD GIK+ F+FELRD G++GFLLP ++I PT +ET +A++ I ++ L H
Sbjct: 386 YDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNH 434
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 230 bits (586), Expect = 2e-60
Identities = 130/380 (34%), Positives = 202/380 (53%), Gaps = 47/380 (12%)
Query: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV 60
+ +++P+ L A F +V P+ +Q ++++L T E+ W P +
Sbjct: 6 LAVLVPIVLFCEQHVFA---FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLI 62
Query: 61 AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHS---YA 117
V F V+ + +++ L+ + + +L+ D+++ I++Q + + R S Y
Sbjct: 63 VKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQIS-NDTVSPRASASYYE 121
Query: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRK-AIFTDCGIH 176
+Y++ +I +W E + +++P+M+++I IGS+ E PLYVLK+ K + K AI+ DCGIH
Sbjct: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181
Query: 177 AREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKN 236
AREW+SPAFC WF+ NRMWRKN
Sbjct: 182 AREWISPAFCLWFI-------------------------------------GHNRMWRKN 204
Query: 237 RSKNQNSKCIGTDLNRNF-NASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLN 295
RS N+ CIGTDLNRNF + W ++ C++ Y G PESE E KAV +F+R ++N
Sbjct: 205 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 264
Query: 296 EIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVL-STRYETRYIYGPIEST 354
+IK YI+ HSYSQ ++FPY YT +HE+L+ VA + T TRY +G T
Sbjct: 265 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 324
Query: 355 IYPISGSSLDWAYDLGIKHT 374
+Y G DW YDLGIK++
Sbjct: 325 LYLAPGGGDDWIYDLGIKYS 344
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 206 bits (523), Expect = 4e-53
Identities = 109/321 (33%), Positives = 185/321 (57%), Gaps = 13/321 (4%)
Query: 15 AIAPVRFDREKVFRVKPQDEKQADIIKDLA--KTNELDFWYPGATHHVAANMMVDFRVSE 72
A+ + F ++V RV +DEKQ ++ DL K ++DFW A ++ VD RV
Sbjct: 31 ALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPAR----PSLPVDMRVPF 86
Query: 73 KESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVK------EDIPGRHSYAKYNNWEKIV 126
E + I++ L+ + + Y I+I D+Q ++++ E SY+ Y+ E+I
Sbjct: 87 SELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIY 146
Query: 127 AWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFC 186
+W + + ++ ++VS+I+IG++ E+ + VLK R AI+ D GIH+REW++ A
Sbjct: 147 SWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATG 206
Query: 187 QWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCI 246
W + YG+++++T +L+ M+ +I V N DG+ ++ + NR+WRKN+S CI
Sbjct: 207 IWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCI 266
Query: 247 GTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSY 306
G DLNRN+ + + + ++PC++ Y G +P+SE E A+ NFI +H N K I+ HSY
Sbjct: 267 GVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSY 325
Query: 307 SQMLLFPYGYTSKLPPNHEDL 327
SQML++PYG + N +L
Sbjct: 326 SQMLMYPYGRLLEPVSNQREL 346
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 145 bits (365), Expect = 9e-35
Identities = 59/120 (49%), Positives = 83/120 (69%)
Query: 139 MVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYG 198
++ IG + E L++LK+G ++ ++A++ DCGIHAREW+ PAFCQWFV +A TY
Sbjct: 11 LIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYK 70
Query: 199 RNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASW 258
+ M K+L+ + FYI+PVFNVDGY +SWT +R WRK RS+N +C G D NRN+ W
Sbjct: 71 SDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKW 130
Score = 82.8 bits (203), Expect = 5e-16
Identities = 40/56 (71%), Positives = 44/56 (78%)
Query: 359 SGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILK 414
SGSS+DWAY GI + FAFELRD G FGFLLPE IKPTC ETMLAVK I ++LK
Sbjct: 135 SGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 190
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 47.0 bits (110), Expect = 3e-05
Identities = 59/267 (22%), Positives = 104/267 (38%), Gaps = 37/267 (13%)
Query: 75 SQAIQSALDQNKMHYEILIHDLQEEIE-KQFDVKEDIPGRHSYAKYNNWEKIVAWTEKMM 133
S + A D +E LI DL E + ++ + +Y++++ + + ++
Sbjct: 888 SSSTNDASDPTTKEFETLIKDLSAENGLESLMLRSSSNLALALYRYHSYKDLSEFLRGLV 947
Query: 134 DKYPEMVSRIKIGSTVEDNPLYVLKIGEKN-----ERRKAIFTDCGIHAREWVSPAFCQW 188
YP + + +G + E ++ L+I K E K F GIH V
Sbjct: 948 MNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV-AGIHGNAPVGTELLLA 1006
Query: 189 FVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKN-RSKNQNSKCIG 247
Y +N +T+L+DR I+P N DG + R K+ SK + G
Sbjct: 1007 LAEFLCLNYKKNPAVTQLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARG 1060
Query: 248 TDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKA-VTNFIRSHLNEIKVYITFHSY 306
DL+ +F TN+ S+ ETKA + N I+ + + +
Sbjct: 1061 KDLDTDF---------TNN-----------ASQPETKAIIENLIQK--QDFSLSVALDGG 1098
Query: 307 SQMLLFPYGYTSKLPPNHEDLAKVAKI 333
S ++ +PY + N E L +A +
Sbjct: 1099 SMLVTYPYDKPVQTVENKETLKHLASL 1125
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/200 (21%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 119 YNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEK---NERRKAIFTDCG- 174
++++ + + + ++YP + +G +VE LYV++I + +E + F G
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
Query: 175 IHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWR 234
+H E V + K +G + +T L+ +++P N DGY S + +
Sbjct: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
Query: 235 KNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHL 294
R+ + N DLNRNF + I + P ET AV ++++S+
Sbjct: 623 IGRNNSNN-----FDLNRNFPDQFVQITDPTQP--------------ETIAVMSWMKSY- 662
Query: 295 NEIKVYITFHSYSQMLLFPY 314
+ H S ++ +P+
Sbjct: 663 -PFVLSANLHGGSLVVNYPF 681
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 43.9 bits (102), Expect = 3e-04
Identities = 46/191 (24%), Positives = 82/191 (42%), Gaps = 24/191 (12%)
Query: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDC---- 173
+++ ++ +V K+ ++ P + IG +VE LYVL+ + + + +
Sbjct: 24 RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 83
Query: 174 GIHAREWVS-PAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTK--N 230
+H E + Q + + RN+ + +L+ +ILP N DGY + + N
Sbjct: 84 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPN 143
Query: 231 RMWRKNRSKNQNSKCIGTDLNRNF---------NASWNSIPNTNDPCADNYRGSAPESEK 281
+ N N G DLNRNF N + PN + P DN++ + E
Sbjct: 144 KPGYLVGRNNAN----GVDLNRNFPDLNTYIYYNEKYGG-PNHHLPLPDNWKS---QVEP 195
Query: 282 ETKAVTNFIRS 292
ET+AV ++ S
Sbjct: 196 ETRAVIRWMHS 206
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 41.2 bits (95), Expect = 0.002
Identities = 41/195 (21%), Positives = 81/195 (41%), Gaps = 26/195 (13%)
Query: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKA----IFTDC 173
+++N++ + +++ ++ P + IG + + LYV+++ +K + +
Sbjct: 298 QHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVA 357
Query: 174 GIHAREWVSPAFCQWFVYQATKTYGR-NKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRM 232
G+H E + + + R N +T+LL M ++LP N DGY ++ +
Sbjct: 358 GMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSE 417
Query: 233 ---WRKNRSKNQNSKCIGTDLNRNF----NASWNS---------IPNTNDPCADNYRGSA 276
W + R NQ+ DLN NF W + +PN + P Y
Sbjct: 418 LVGWAEGRWNNQS-----IDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPN 472
Query: 277 PESEKETKAVTNFIR 291
ET+AV +++
Sbjct: 473 ATVAPETRAVIKWMK 487
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 35.0 bits (79), Expect = 0.13
Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%)
Query: 119 YNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTD----CG 174
Y+ E + A+ + + Y + IG +V+ L+VL +G + + +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 175 IHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWR 234
+H E V + + G++ +T L++ +I+P N DG+ + K +
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF-EAVKKPDCYY 140
Query: 235 KNRSKNQNSKCIGTDLNRNF 254
+N N DLNRNF
Sbjct: 141 SIGRENYNQ----YDLNRNF 156
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 35.0 bits (79), Expect = 0.13
Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%)
Query: 119 YNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTD----CG 174
Y+ E + A+ + + Y + IG +V+ L+VL +G + + +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 175 IHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWR 234
+H E V + + G++ +T L++ +I+P N DG+ + K +
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF-EAVKKPDCYY 140
Query: 235 KNRSKNQNSKCIGTDLNRNF 254
+N N DLNRNF
Sbjct: 141 SIGRENYNQ----YDLNRNF 156
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 35.0 bits (79), Expect = 0.13
Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 9/140 (6%)
Query: 119 YNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTD----CG 174
Y+ E + A+ + + Y + IG +V+ L+VL +G + + +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 175 IHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWR 234
+H E V + + G++ +T L++ +I+P N DG+ + K +
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGF-EAVKKPDCYY 140
Query: 235 KNRSKNQNSKCIGTDLNRNF 254
+N N DLNRNF
Sbjct: 141 SIGRENYNQ----YDLNRNF 156
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 34.7 bits (78), Expect = 0.16
Identities = 29/141 (20%), Positives = 61/141 (43%), Gaps = 23/141 (16%)
Query: 27 FRVKPQDEKQADIIKDLAK---------------TNELDFWYPGATHHVA-----ANMMV 66
FR+ K+ D +KD K ++E D+ Y A V +N V
Sbjct: 539 FRINLPKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPV 598
Query: 67 DFRVSEKESQAIQ---SALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWE 123
V E Q ++ SAL++ ++ YE + L++++ + P R +Y+ +
Sbjct: 599 QNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQ 658
Query: 124 KIVAWTEKMMDKYPEMVSRIK 144
K+ W E+ + + + +++++
Sbjct: 659 KVTQWAEERDELFRQSLAKLR 679
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 34.7 bits (78), Expect = 0.16
Identities = 29/141 (20%), Positives = 61/141 (43%), Gaps = 23/141 (16%)
Query: 27 FRVKPQDEKQADIIKDLAK---------------TNELDFWYPGATHHVA-----ANMMV 66
FR+ K+ D +KD K ++E D+ Y A V +N V
Sbjct: 539 FRINLPKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPV 598
Query: 67 DFRVSEKESQAIQ---SALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWE 123
V E Q ++ SAL++ ++ YE + L++++ + P R +Y+ +
Sbjct: 599 QNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQ 658
Query: 124 KIVAWTEKMMDKYPEMVSRIK 144
K+ W E+ + + + +++++
Sbjct: 659 KVTQWAEERDELFRQSLAKLR 679
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 34.7 bits (78), Expect = 0.16
Identities = 29/141 (20%), Positives = 61/141 (43%), Gaps = 23/141 (16%)
Query: 27 FRVKPQDEKQADIIKDLAK---------------TNELDFWYPGATHHVA-----ANMMV 66
FR+ K+ D +KD K ++E D+ Y A V +N V
Sbjct: 539 FRINLPKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPV 598
Query: 67 DFRVSEKESQAIQ---SALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWE 123
V E Q ++ SAL++ ++ YE + L++++ + P R +Y+ +
Sbjct: 599 QNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQ 658
Query: 124 KIVAWTEKMMDKYPEMVSRIK 144
K+ W E+ + + + +++++
Sbjct: 659 KVTQWAEERDELFRQSLAKLR 679
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 34.7 bits (78), Expect = 0.16
Identities = 29/141 (20%), Positives = 61/141 (43%), Gaps = 23/141 (16%)
Query: 27 FRVKPQDEKQADIIKDLAK---------------TNELDFWYPGATHHVA-----ANMMV 66
FR+ K+ D +KD K ++E D+ Y A V +N V
Sbjct: 539 FRINLPKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPV 598
Query: 67 DFRVSEKESQAIQ---SALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWE 123
V E Q ++ SAL++ ++ YE + L++++ + P R +Y+ +
Sbjct: 599 QNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQ 658
Query: 124 KIVAWTEKMMDKYPEMVSRIK 144
K+ W E+ + + + +++++
Sbjct: 659 KVTQWAEERDELFRQSLAKLR 679
>gi|46409372 G protein-coupled receptor 153 [Homo sapiens]
Length = 609
Score = 32.7 bits (73), Expect = 0.63
Identities = 41/162 (25%), Positives = 64/162 (39%), Gaps = 15/162 (9%)
Query: 3 LILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQAD-------IIKDLAKTNELDFWYPG 55
L+LPV L A A ++ REK + DE+ D I DL LD+ Y G
Sbjct: 291 LLLPVFLWACDRYRADLKAVREKCMALMANDEESDDETSLEGGISPDLVLERSLDYGYGG 350
Query: 56 ATHHVAANMMVDFRVSEKESQAIQ----SALDQNKMHYEILIHDLQEEIEKQFDVKEDIP 111
VA + M + +S E Q L ++KM Y + + + DV +P
Sbjct: 351 --DFVALDRMAKYEISALEGGLPQLYPLRPLQEDKMQY-LQVPPTRRFSHDDADVWAAVP 407
Query: 112 GRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNP 153
++ + E + A ++ PE R + + ED P
Sbjct: 408 LPAFLPRWGSGEDLAALAHLVLPAGPER-RRASLLAFAEDAP 448
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 32.3 bits (72), Expect = 0.82
Identities = 32/151 (21%), Positives = 57/151 (37%), Gaps = 25/151 (16%)
Query: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI----GEKNERRKAIFTDC 173
K++N++++ + + + P + IG + + LY ++I GE
Sbjct: 317 KHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIA 376
Query: 174 GIHAREWVSPAFCQWFVYQATKTY-GRNKIMTKLLDRMNFYILPVFNVDGY--------- 223
G H E + V + Y RN + L++ ++LP N DGY
Sbjct: 377 GAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGSE 436
Query: 224 IWSWTKNRMWRKNRSKNQNSKCIGTDLNRNF 254
+ W+ R W + G D+N NF
Sbjct: 437 LGGWSLGR-WTHD----------GIDINNNF 456
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 31.6 bits (70), Expect = 1.4
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 14/66 (21%)
Query: 34 EKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILI 93
EKQ D +DL K E HH+ + +EKES+A+ SAL+ K YE
Sbjct: 564 EKQRDCSQDLLKKRE---------HHIE-QLNDKLSKTEKESKALLSALELKKKEYE--- 610
Query: 94 HDLQEE 99
+L+EE
Sbjct: 611 -ELKEE 615
>gi|4505379 nuclear factor erythroid 2-like 1 [Homo sapiens]
Length = 772
Score = 31.2 bits (69), Expect = 1.8
Identities = 16/57 (28%), Positives = 25/57 (43%)
Query: 34 EKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYE 90
+K+ D+ K+L E D W +A N++VD E + S DQ + E
Sbjct: 198 QKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPAQVPSGEDQTALSLE 254
>gi|118600961 akt substrate AS250 [Homo sapiens]
Length = 1873
Score = 31.2 bits (69), Expect = 1.8
Identities = 15/74 (20%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 230 NRMWRKNRSKNQNSKCI-----GTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETK 284
+++ + K + C+ GT + R+F+ SW S P+ +P +R + +
Sbjct: 666 DKLSEQKEKKQRGKGCVLDPQKGTTVGRSFSLSWRSHPDVTEPM--RFRSATTSGAPGVE 723
Query: 285 AVTNFIRSHLNEIK 298
N +R E++
Sbjct: 724 KARNIVRQKATEVE 737
>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
Length = 343
Score = 30.8 bits (68), Expect = 2.4
Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 18/140 (12%)
Query: 8 GLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVD 67
G +TT AIAPV + QDEK L + E + W + ++ V
Sbjct: 66 GAPSTTNAIAPVSCSSNE--GASSQDEKS------LGSSREAEGWKEDPLNKKVVSL-VH 116
Query: 68 FRVSEKESQA-------IQSALDQNKMHYEILIHDLQEEIEKQF--DVKEDIPGRHSYAK 118
F + + E++ I+ + ++K H+ ++ E +E D+KE P RH YA
Sbjct: 117 FLLQKYETKEPITKGDMIKFVIRKDKCHFNEILKRASEHMELALGVDLKEVDPIRHYYAF 176
Query: 119 YNNWEKIVAWTEKMMDKYPE 138
++ + T +K P+
Sbjct: 177 FSKLDLTYDETTSDEEKIPK 196
>gi|145386551 SH3 domain and tetratricopeptide repeats 1 [Homo
sapiens]
Length = 1336
Score = 30.4 bits (67), Expect = 3.1
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 8/49 (16%)
Query: 55 GATHHVAANMMVD-----FRVSEKESQAIQSALDQNKM---HYEILIHD 95
G THH AN+++D SE+E AIQ +D+N + H +LI +
Sbjct: 161 GFTHHCLANLLMDQAFWLLLPSEEEETAIQVHVDENALRLTHESLLIQE 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,715,822
Number of Sequences: 37866
Number of extensions: 674583
Number of successful extensions: 1621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1558
Number of HSP's gapped (non-prelim): 59
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.