Guide to the Human Genome
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Search of human proteins with 221307490

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221307490 lengsin, lens protein with glutamine synthetase
domain isoform b [Homo sapiens]
         (208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221307490 lengsin, lens protein with glutamine synthetase dom...   422   e-118
gi|221307485 lengsin, lens protein with glutamine synthetase dom...   360   e-100
gi|193290160 CTAGE family, member 4 [Homo sapiens]                     29   2.5  
gi|56847634 hypothetical protein LOC441294 [Homo sapiens]              29   2.5  
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    29   3.2  
gi|5453974 protein kinase N2 [Homo sapiens]                            28   4.2  
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    28   5.5  
gi|61835172 fragile X mental retardation-related protein 1 isofo...    28   7.2  
gi|61835148 fragile X mental retardation-related protein 1 isofo...    28   7.2  
gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]    27   9.4  
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    27   9.4  
gi|146262005 CTAGE family, member 6 [Homo sapiens]                     27   9.4  

>gi|221307490 lengsin, lens protein with glutamine synthetase domain
           isoform b [Homo sapiens]
          Length = 208

 Score =  422 bits (1084), Expect = e-118
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MNNEEDLLQEDSTRDEGNETEANSMNTLRRTRKKVTKPYVCSTEVGETDMSNSNDCMRDS 60
           MNNEEDLLQEDSTRDEGNETEANSMNTLRRTRKKVTKPYVCSTEVGETDMSNSNDCMRDS
Sbjct: 1   MNNEEDLLQEDSTRDEGNETEANSMNTLRRTRKKVTKPYVCSTEVGETDMSNSNDCMRDS 60

Query: 61  SQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMP 120
           SQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMP
Sbjct: 61  SQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMP 120

Query: 121 RGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTVSGM 180
           RGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTVSGM
Sbjct: 121 RGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTVSGM 180

Query: 181 SIGRKTCSAALLELSSSRSLGKNGWQDS 208
           SIGRKTCSAALLELSSSRSLGKNGWQDS
Sbjct: 181 SIGRKTCSAALLELSSSRSLGKNGWQDS 208


>gi|221307485 lengsin, lens protein with glutamine synthetase domain
           isoform a [Homo sapiens]
          Length = 509

 Score =  360 bits (924), Expect = e-100
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 1   MNNEEDLLQEDSTRDEGNETEANSMNTLRRTRKKVTKPYVCSTEVGETDMSNSNDCMRDS 60
           MNNEEDLLQEDSTRDEGNETEANSMNTLRRTRKKVTKPYVCSTEVGETDMSNSNDCMRDS
Sbjct: 1   MNNEEDLLQEDSTRDEGNETEANSMNTLRRTRKKVTKPYVCSTEVGETDMSNSNDCMRDS 60

Query: 61  SQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMP 120
           SQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMP
Sbjct: 61  SQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHGVCMP 120

Query: 121 RGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVT 176
           RGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVT
Sbjct: 121 RGYLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVT 176


>gi|193290160 CTAGE family, member 4 [Homo sapiens]
          Length = 777

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 24/119 (20%), Positives = 54/119 (45%), Gaps = 9/119 (7%)

Query: 1   MNNEEDLLQEDSTRDEGNETEANSM--------NTLRRTRKKVTKPYVCSTEVGETDMSN 52
           M ++  +L+ED+T D+  E E NS         + L+   KK+      +  +   +   
Sbjct: 276 MKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGER 335

Query: 53  SNDCMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQE 111
           ++  ++ S    T  +L+  +K+++   A  + + + FE+ +   + +   I   F+QE
Sbjct: 336 NHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESEN-QKLQQKLKIMTEFYQE 393


>gi|56847634 hypothetical protein LOC441294 [Homo sapiens]
          Length = 777

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 24/119 (20%), Positives = 54/119 (45%), Gaps = 9/119 (7%)

Query: 1   MNNEEDLLQEDSTRDEGNETEANSM--------NTLRRTRKKVTKPYVCSTEVGETDMSN 52
           M ++  +L+ED+T D+  E E NS         + L+   KK+      +  +   +   
Sbjct: 276 MKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGER 335

Query: 53  SNDCMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQE 111
           ++  ++ S    T  +L+  +K+++   A  + + + FE+ +   + +   I   F+QE
Sbjct: 336 NHIIIQLSEVDKTKEELTEHIKNLQTQQASLQSENIYFESEN-QKLQQKLKIMTEFYQE 393


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 19/86 (22%)

Query: 7   LLQEDSTRDEGNETEANSMNTLRRTRKKVTK----------PYVC-------STEVGETD 49
           +L    TR+  N  +    N +++ RKK TK             C       S+E GE D
Sbjct: 433 ILPGSKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDD 492

Query: 50  MSN--SNDCMRDSSQILTPPQLSSRM 73
             +  S+ C++ S  +L  P L S +
Sbjct: 493 RDSLGSSGCLKGSPLVLKDPSLFSSL 518


>gi|5453974 protein kinase N2 [Homo sapiens]
          Length = 984

 Score = 28.5 bits (62), Expect = 4.2
 Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)

Query: 33  KKVTKPYVCSTEVGETDMSNSNDCMRDSSQILTPPQLSSRMKHIRQAMAKN 83
           KKV  P++  T  G  D+SN +D     + ILTPP+    +    Q M ++
Sbjct: 927 KKVKPPFI-PTIRGREDVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRD 976


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 28.1 bits (61), Expect = 5.5
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 5/56 (8%)

Query: 2   NNEEDLLQEDSTRDEGNETEANSMNTLRRTRKKV--TKPYVCSTEVGETDMSNSND 55
           N ++D   ED  +  G+E+E +  +  R+T+KKV   K    S++ G    S+S++
Sbjct: 720 NEDQD---EDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSE 772


>gi|61835172 fragile X mental retardation-related protein 1 isoform
           c [Homo sapiens]
          Length = 536

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 23/97 (23%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 6   DLLQEDSTRDEGNETEANSMNTLRRTRKKVT-KPYVCSTEVGETDMSNSND-CMRDSSQI 63
           D  + D T D       +S N  RR+R++ T +  V    + E+D ++ N+  +   +  
Sbjct: 396 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY 455

Query: 64  LTPPQLSSRMKHI-RQAMAKNRLQFVRFEATDLHGVS 99
           ++  +  SR +++ R+ +AKN+ +  + +  + HG S
Sbjct: 456 ISRAESQSRQRNLPRETLAKNKKEMAK-DVIEEHGPS 491


>gi|61835148 fragile X mental retardation-related protein 1 isoform
           a [Homo sapiens]
          Length = 621

 Score = 27.7 bits (60), Expect = 7.2
 Identities = 23/97 (23%), Positives = 49/97 (50%), Gaps = 4/97 (4%)

Query: 6   DLLQEDSTRDEGNETEANSMNTLRRTRKKVT-KPYVCSTEVGETDMSNSND-CMRDSSQI 63
           D  + D T D       +S N  RR+R++ T +  V    + E+D ++ N+  +   +  
Sbjct: 481 DNTESDQTADTDASESHHSTNRRRRSRRRRTDEDAVLMDGMTESDTASVNENGLVTVADY 540

Query: 64  LTPPQLSSRMKHI-RQAMAKNRLQFVRFEATDLHGVS 99
           ++  +  SR +++ R+ +AKN+ +  + +  + HG S
Sbjct: 541 ISRAESQSRQRNLPRETLAKNKKEMAK-DVIEEHGPS 576


>gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]
          Length = 6306

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 11/40 (27%), Positives = 25/40 (62%)

Query: 100 RSKTIPAHFFQEKVSHGVCMPRGYLEVIPNPKDNEMNNIR 139
           R++++P    +EK ++G+ M    +E  PNP D +++ ++
Sbjct: 163 RNESMPLTLIREKGTYGMVMVTFEVEGGPNPPDEDLSPVK 202


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 13/35 (37%), Positives = 18/35 (51%)

Query: 170  CDTFTVTVSGMSIGRKTCSAALLELSSSRSLGKNG 204
            CD       G  IG  +C+AA ++ SS +SL   G
Sbjct: 1635 CDVAVALQFGAEIGNYSCAAAGVQTSSKKSLDLTG 1669


>gi|146262005 CTAGE family, member 6 [Homo sapiens]
          Length = 777

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 23/119 (19%), Positives = 53/119 (44%), Gaps = 9/119 (7%)

Query: 1   MNNEEDLLQEDSTRDEGNETEANSM--------NTLRRTRKKVTKPYVCSTEVGETDMSN 52
           M ++  +L+ED+T D+  E E NS         + L+   KK+      +  +   +   
Sbjct: 276 MKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGER 335

Query: 53  SNDCMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQE 111
           ++  ++ S    T  +L+  +K+++      + + + FE+ +   + +   I   F+QE
Sbjct: 336 NHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESEN-QKLQQKLKIMTEFYQE 393


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.128    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,372,843
Number of Sequences: 37866
Number of extensions: 286263
Number of successful extensions: 764
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 759
Number of HSP's gapped (non-prelim): 12
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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