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Search of human proteins with 219555665
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219555665 solute carrier family 25, member 39 isoform a
[Homo sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 721 0.0
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 697 0.0
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 347 1e-95
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 102 7e-22
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 98 1e-20
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 97 2e-20
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 97 2e-20
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 97 2e-20
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 97 3e-20
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 97 3e-20
gi|157388925 solute carrier family 25, member 38 [Homo sapiens] 96 5e-20
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 96 5e-20
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 94 2e-19
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 93 4e-19
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 91 2e-18
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 90 3e-18
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 90 3e-18
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 90 3e-18
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 90 3e-18
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 90 3e-18
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 90 3e-18
gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo ... 88 1e-17
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 86 5e-17
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 83 4e-16
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 82 7e-16
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 80 2e-15
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 77 2e-14
gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens] 77 2e-14
gi|13259541 uncoupling protein 2 [Homo sapiens] 76 4e-14
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 76 5e-14
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 721 bits (1862), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 60
MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS
Sbjct: 1 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 60
Query: 61 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 120
YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT
Sbjct: 61 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 120
Query: 121 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 180
RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS
Sbjct: 121 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 180
Query: 181 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 240
PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV
Sbjct: 181 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 240
Query: 241 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 300
KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV
Sbjct: 241 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 300
Query: 301 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 359
DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG
Sbjct: 301 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 359
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 697 bits (1798), Expect = 0.0
Identities = 350/359 (97%), Positives = 350/359 (97%), Gaps = 8/359 (2%)
Query: 1 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 60
MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS
Sbjct: 1 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 60
Query: 61 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 120
YTK KCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT
Sbjct: 61 YTKW--------KCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 112
Query: 121 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 180
RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS
Sbjct: 113 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVIS 172
Query: 181 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 240
PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV
Sbjct: 173 PLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELV 232
Query: 241 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 300
KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV
Sbjct: 233 KSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHV 292
Query: 301 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 359
DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG
Sbjct: 293 DSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG 351
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 347 bits (889), Expect = 1e-95
Identities = 179/353 (50%), Positives = 241/353 (68%), Gaps = 26/353 (7%)
Query: 4 QDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTK 63
Q+ ++PLQQM+AS TGA++TS+ +TPLDVVK+RLQ+Q
Sbjct: 8 QEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQN------------------NP 49
Query: 64 LPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTL 123
LP GKC +Y NG+++ L +C G W++ P F GT+DAF KI+R+EG ++L
Sbjct: 50 LPK-----GKCFVYSNGLMDHLCVCEEGGN-KLWYKKPGNFQGTLDAFFKIIRNEGIKSL 103
Query: 124 WSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLE 183
WSGLP TLVM VPAT IYFT YDQL A L + ++ P+VAG +AR G VTVISPLE
Sbjct: 104 WSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLE 163
Query: 184 LMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSW 243
L+RTK+Q++ SY EL V V++ GW SLW GW PT LRDVPFSA+YW+NYE++K W
Sbjct: 164 LIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKW 223
Query: 244 LNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVN-PLHVDS 302
L + + ++F +G +SG+ AAV TLPFDVVKTQ+Q L E+ +++ PLH+ S
Sbjct: 224 LCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHM-S 282
Query: 303 TWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDR 355
TW++++ I A++G GLF+G +PR+IK AP+CAIMISTYEFGK+FFQ+ N R
Sbjct: 283 TWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRR 335
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 102 bits (253), Expect = 7e-22
Identities = 66/232 (28%), Positives = 112/232 (48%), Gaps = 9/232 (3%)
Query: 114 IVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARL 173
+V G R+LW G ++ P +AI F AY+Q+K + G+ T + VAG+LA
Sbjct: 232 MVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGA 291
Query: 174 GTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSAL 232
T+I P+E+++T+L + Y+ L C R + + G R+ + G+ P L +P++ +
Sbjct: 292 TAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGI 351
Query: 233 YWFNYELVKSWLNGFRPKDQTSVG--MSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAM 290
YE +K+W D G + G IS T + + P +V+T+ Q
Sbjct: 352 DLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIE 411
Query: 291 EAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
+++ L LLR I ++ G +GL+ G P +K P+ +I YE
Sbjct: 412 GGPQLSMLG------LLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457
Score = 73.2 bits (178), Expect = 3e-13
Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 17/190 (8%)
Query: 161 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGAC--VRTAVAQGGWRSLWLG 218
L A VAGA++R GT +PL+ ++ +Q L +R+ V +GG RSLW G
Sbjct: 189 LVAGAVAGAVSRTGT----APLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRG 244
Query: 219 WGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDV 278
G L+ P SA+ + YE +K + G ++ V FVAG ++G A + P +V
Sbjct: 245 NGINVLKIAPESAIKFMAYEQIKRAILG--QQETLHVQERFVAGSLAGATAQTIIYPMEV 302
Query: 279 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 338
+KT+ + ++ RRI G + + G+LP ++ P I +
Sbjct: 303 LKTRLTLRRTGQYKGLLD---------CARRILEREGPRAFYRGYLPNVLGIIPYAGIDL 353
Query: 339 STYEFGKSFF 348
+ YE K+++
Sbjct: 354 AVYETLKNWW 363
Score = 29.6 bits (65), Expect = 4.4
Identities = 12/39 (30%), Positives = 21/39 (53%)
Query: 114 IVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
I+ EG R L+ G+ + +PA +I + Y+ +K L
Sbjct: 425 ILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 97.8 bits (242), Expect = 1e-20
Identities = 84/310 (27%), Positives = 140/310 (45%), Gaps = 30/310 (9%)
Query: 58 SLSYTKLPSSLQ-STGKCLLYCNGVLEPLYLCPNGA---RCATWFQDP-TRFTGTMDAFV 112
S Y LP+S ST G+LE + P + R + DP ++T A
Sbjct: 33 SEDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALK 92
Query: 113 KIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLY--------AP 164
KI+R EG G+ ++ PA A+YF Y+ +K L +D++ A
Sbjct: 93 KIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTL------NDVFHHQGNSHLAN 146
Query: 165 MVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
+AG++A L V++P E+++ +LQ + +R +C+RT G + + +
Sbjct: 147 GIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLT 206
Query: 225 RDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQ 284
++PF ++++ YE ++ +N R + S ++GG++G +AA T P DV KT
Sbjct: 207 MNIPFQSIHFITYEFLQEQVNPHRTYNPQS---HIISGGLAGALAAAATTPLDVCKT--- 260
Query: 285 VALGAMEAVRVNPLHVDSTWL----LLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMIST 340
L E V ++ ++ R + +G G F G R+I PS AI S
Sbjct: 261 -LLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSV 319
Query: 341 YEFGKSFFQR 350
YEF K F +
Sbjct: 320 YEFFKYFLTK 329
Score = 34.3 bits (77), Expect = 0.18
Identities = 17/55 (30%), Positives = 30/55 (54%)
Query: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL 157
R +G +AF + + G + G+ A ++ +P+TAI ++ Y+ K FL R L
Sbjct: 278 RLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQL 332
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 97.4 bits (241), Expect = 2e-20
Identities = 65/236 (27%), Positives = 112/236 (47%), Gaps = 11/236 (4%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGAL 170
F ++V+ G R+LW G ++ P TA+ F AY+Q K L + ++G++
Sbjct: 238 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 297
Query: 171 ARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 229
A T I P+E+M+T+L Y + C + + G + + G+ P L +P+
Sbjct: 298 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 357
Query: 230 SALYWFNYELVKS-WLNGFRPKDQTSVGMSFV--AGGISGTVAAVLTLPFDVVKTQRQVA 286
+ + YEL+KS WL+ F KD + G+ + G +S T + + P +V+T+ Q
Sbjct: 358 AGIDLAVYELLKSYWLDNF-AKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 416
Query: 287 LGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
+ ++N + L RRI ++ G GL+ G P +K P+ I YE
Sbjct: 417 AMLEGSPQLNMVG------LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 466
Score = 59.3 bits (142), Expect = 5e-09
Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 17/190 (8%)
Query: 161 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGAC--VRTAVAQGGWRSLWLG 218
L A +AGA++R T +PL+ ++ +Q ++ R V +GG RSLW G
Sbjct: 198 LLAGGIAGAVSRTST----APLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 253
Query: 219 WGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDV 278
G ++ P +A+ ++ YE K L K T F++G ++G A P +V
Sbjct: 254 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE--RFISGSMAGATAQTFIYPMEV 311
Query: 279 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 338
+KT+ V + + ++I G + G++P ++ P I +
Sbjct: 312 MKTRLAVGKTGQYS---------GIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362
Query: 339 STYEFGKSFF 348
+ YE KS++
Sbjct: 363 AVYELLKSYW 372
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 97.4 bits (241), Expect = 2e-20
Identities = 68/248 (27%), Positives = 122/248 (49%), Gaps = 11/248 (4%)
Query: 98 FQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRAL 157
+ T FT + +V+ G R+LW G ++ P AI F+ ++Q K + CG
Sbjct: 123 YSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQG 182
Query: 158 TSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLW 216
+ ++AG+LA + T+I+P+E+++T+L + Y+ L C R + + G R+L+
Sbjct: 183 SPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALY 242
Query: 217 LGWGPTALRDVPFSALYWFNYELVKS-WLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLP 275
G+ P L +P++ YE+++ W+ R S +S + +S T + + P
Sbjct: 243 RGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYP 302
Query: 276 FDVVKTQRQVALGAMEAVR-VNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSC 334
+V+T+ Q A + V NP + +L+RI A+ G GL+ G P ++K P+
Sbjct: 303 LTLVRTRMQ----AQDTVEGSNP----TMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAG 354
Query: 335 AIMISTYE 342
I YE
Sbjct: 355 GISYVVYE 362
Score = 61.2 bits (147), Expect = 1e-09
Identities = 50/203 (24%), Positives = 97/203 (47%), Gaps = 21/203 (10%)
Query: 156 ALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQ--AQHVSYRELGACVRTAVAQGGWR 213
AL L + +AGA++R GT +PL+ + +Q + ++ L +++ V +GG+R
Sbjct: 91 ALWKFLLSGAMAGAVSRTGT----APLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFR 146
Query: 214 SLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFR--PKDQTSVGMSFVAGGISGTVAAV 271
SLW G G L+ P A+ + +E K++ G + P Q + +AG ++ ++
Sbjct: 147 SLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERL----LAGSLAVAISQT 202
Query: 272 LTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAA 331
L P +V+KT+ + ++ R+I GT+ L+ G+LP ++
Sbjct: 203 LINPMEVLKTRLTLRRTGQYKGLLD---------CARQILQREGTRALYRGYLPNMLGII 253
Query: 332 PSCAIMISTYEFGKSFFQRLNQD 354
P ++ YE + F+ + +D
Sbjct: 254 PYACTDLAVYEMLQCFWVKSGRD 276
Score = 56.6 bits (135), Expect = 3e-08
Identities = 42/153 (27%), Positives = 71/153 (46%), Gaps = 16/153 (10%)
Query: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLY 162
++ G +D +I++ EGTR L+ G ++ +P Y+ L+ F D+
Sbjct: 221 QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKSG--RDMG 278
Query: 163 APMVAGALARLGTVTVIS--------PLELMRTKLQAQHV---SYRELGACVRTAVAQGG 211
P L L +VT+ + PL L+RT++QAQ S + ++ +AQ G
Sbjct: 279 DP---SGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILAQQG 335
Query: 212 WRSLWLGWGPTALRDVPFSALYWFNYELVKSWL 244
W L+ G PT L+ +P + + YE +K L
Sbjct: 336 WLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 97.4 bits (241), Expect = 2e-20
Identities = 65/236 (27%), Positives = 112/236 (47%), Gaps = 11/236 (4%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGAL 170
F ++V+ G R+LW G ++ P TA+ F AY+Q K L + ++G++
Sbjct: 219 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 278
Query: 171 ARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 229
A T I P+E+M+T+L Y + C + + G + + G+ P L +P+
Sbjct: 279 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 338
Query: 230 SALYWFNYELVKS-WLNGFRPKDQTSVGMSFV--AGGISGTVAAVLTLPFDVVKTQRQVA 286
+ + YEL+KS WL+ F KD + G+ + G +S T + + P +V+T+ Q
Sbjct: 339 AGIDLAVYELLKSYWLDNF-AKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 397
Query: 287 LGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
+ ++N + L RRI ++ G GL+ G P +K P+ I YE
Sbjct: 398 AMLEGSPQLNMVG------LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
Score = 59.3 bits (142), Expect = 5e-09
Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 17/190 (8%)
Query: 161 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGAC--VRTAVAQGGWRSLWLG 218
L A +AGA++R T +PL+ ++ +Q ++ R V +GG RSLW G
Sbjct: 179 LLAGGIAGAVSRTST----APLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 234
Query: 219 WGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDV 278
G ++ P +A+ ++ YE K L K T F++G ++G A P +V
Sbjct: 235 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE--RFISGSMAGATAQTFIYPMEV 292
Query: 279 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 338
+KT+ V + + ++I G + G++P ++ P I +
Sbjct: 293 MKTRLAVGKTGQYS---------GIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343
Query: 339 STYEFGKSFF 348
+ YE KS++
Sbjct: 344 AVYELLKSYW 353
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 96.7 bits (239), Expect = 3e-20
Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 10/246 (4%)
Query: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 163
+ + D F K++R+EG L+ GL L+ P AI T D ++ + + L A
Sbjct: 371 YKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA 430
Query: 164 PMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 223
++AG A V +PLE+++ +LQ + V G+ ++ G
Sbjct: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 490
Query: 224 LRDVPFSALYWFNYELVKSWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
LRD+PFSA+Y+ Y VK+ F +D Q S G +AG I+G AA L P DV+KT+
Sbjct: 491 LRDIPFSAIYFPCYAHVKA---SFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 547
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
QVA A + + R+I E G K L+ G R+ +++P + + TYE
Sbjct: 548 LQVAARAGQTTYSGVID------CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 601
Query: 343 FGKSFF 348
+ +F
Sbjct: 602 LLQRWF 607
Score = 43.1 bits (100), Expect = 4e-04
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 259 FVAGGISGTVAAVLTLPFDVVKT--QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGT 316
F G ++G V A P D+VKT Q Q + G+ V L +++ +++ G
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF----VGELMYKNSFDCFKKVLRYEGF 387
Query: 317 KGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 348
GL+ G LP+++ AP AI ++ +F + F
Sbjct: 388 FGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 419
Score = 37.7 bits (86), Expect = 0.016
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 102 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 149
T ++G +D F KI+R EG + LW G A + + P + Y+ L+
Sbjct: 557 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 604
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 96.7 bits (239), Expect = 3e-20
Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 10/246 (4%)
Query: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 163
+ + D F K++R+EG L+ GL L+ P AI T D ++ + + L A
Sbjct: 372 YKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLAA 431
Query: 164 PMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 223
++AG A V +PLE+++ +LQ + V G+ ++ G
Sbjct: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACF 491
Query: 224 LRDVPFSALYWFNYELVKSWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
LRD+PFSA+Y+ Y VK+ F +D Q S G +AG I+G AA L P DV+KT+
Sbjct: 492 LRDIPFSAIYFPCYAHVKA---SFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTR 548
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
QVA A + + R+I E G K L+ G R+ +++P + + TYE
Sbjct: 549 LQVAARAGQTTYSGVID------CFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYE 602
Query: 343 FGKSFF 348
+ +F
Sbjct: 603 LLQRWF 608
Score = 43.1 bits (100), Expect = 4e-04
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 259 FVAGGISGTVAAVLTLPFDVVKT--QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGT 316
F G ++G V A P D+VKT Q Q + G+ V L +++ +++ G
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSF----VGELMYKNSFDCFKKVLRYEGF 388
Query: 317 KGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 348
GL+ G LP+++ AP AI ++ +F + F
Sbjct: 389 FGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKF 420
Score = 37.7 bits (86), Expect = 0.016
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 102 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 149
T ++G +D F KI+R EG + LW G A + + P + Y+ L+
Sbjct: 558 TTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQ 605
>gi|157388925 solute carrier family 25, member 38 [Homo sapiens]
Length = 304
Score = 95.9 bits (237), Expect = 5e-20
Identities = 82/314 (26%), Positives = 137/314 (43%), Gaps = 31/314 (9%)
Query: 39 LQSQRPSM-----ASELMPSSRLWSLSYTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGAR 93
+Q+ RPS+ + + + L + L S+ T LL+ +PL L +
Sbjct: 2 IQNSRPSLLQPQDVGDTVETLMLHPVIKAFLCGSISGTCSTLLF-----QPLDLLKTRLQ 56
Query: 94 CATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYF-TAYDQLKAFL 152
+R G + +K+VR E LW G+ ++V VP IYF T Y + FL
Sbjct: 57 TLQPSDHGSRRVGMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFL 116
Query: 153 CGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGW 212
G T+ ++ G +R +SP+ +++T+ ++ Y + A +R+ G
Sbjct: 117 RGHPPTA--LESVMLGVGSRSVAGVCMSPITVIKTRYESGKYGYESIYAALRSIYHSEGH 174
Query: 213 RSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGM----SFVAGGISGTV 268
R L+ G T LRD PFS +Y Y K+ + P DQ + +F G +G +
Sbjct: 175 RGLFSGLTATLLRDAPFSGIYLMFYNQTKNIV----PHDQVDATLIPITNFSCGIFAGIL 230
Query: 269 AAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRII 328
A+++T P DV+KT Q + PL + I + G +G F G +PR +
Sbjct: 231 ASLVTQPADVIKTHMQ----------LYPLKFQWIGQAVTLIFKDYGLRGFFQGGIPRAL 280
Query: 329 KAAPSCAIMISTYE 342
+ A+ + YE
Sbjct: 281 RRTLMAAMAWTVYE 294
Score = 58.2 bits (139), Expect = 1e-08
Identities = 57/205 (27%), Positives = 89/205 (43%), Gaps = 34/205 (16%)
Query: 148 LKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVS---YRELG--AC 202
+KAFLCG ++G + L + PL+L++T+LQ S R +G A
Sbjct: 28 IKAFLCGS----------ISGTCSTL----LFQPLDLLKTRLQTLQPSDHGSRRVGMLAV 73
Query: 203 VRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFN-YELVKSWLNGFRPKDQTSVGMSFVA 261
+ V LW G P+ +R VP +Y+ Y L + +L G P SV +
Sbjct: 74 LLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESV----ML 129
Query: 262 GGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFA 321
G S +VA V P V+KT+ + E++ + LR I G +GLF+
Sbjct: 130 GVGSRSVAGVCMSPITVIKTRYESGKYGYESI----------YAALRSIYHSEGHRGLFS 179
Query: 322 GFLPRIIKAAPSCAIMISTYEFGKS 346
G +++ AP I + Y K+
Sbjct: 180 GLTATLLRDAPFSGIYLMFYNQTKN 204
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 95.9 bits (237), Expect = 5e-20
Identities = 89/360 (24%), Positives = 137/360 (38%), Gaps = 78/360 (21%)
Query: 6 PAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLP 65
PAG + MVA ++ M P+D VK R+QS +P A+
Sbjct: 67 PAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARY--------------- 111
Query: 66 SSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWS 125
VLE L+ +I+R EG
Sbjct: 112 -------------RNVLEALW--------------------------RIIRTEGLWRPMR 132
Query: 126 GLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAP--------MVAGALARLGTVT 177
GL T PA A+YF Y++LK L SD+ P AG +A L
Sbjct: 133 GLNVTATGAGPAHALYFACYEKLKKTL------SDVIHPGGNSHIANGAAGCVATLLHDA 186
Query: 178 VISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNY 237
++P E+++ ++Q + Y + CVR G + + + +VPF A+++ Y
Sbjct: 187 AMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTY 246
Query: 238 ELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNP 297
E ++ F P+ + + ++G +G VAA T P DV KT L E++ +N
Sbjct: 247 EFLQ---EHFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKT----LLNTQESLALNS 299
Query: 298 L---HVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQD 354
H+ R + G F G R+I PS AI S YEF K + ++
Sbjct: 300 HITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEE 359
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 94.0 bits (232), Expect = 2e-19
Identities = 94/356 (26%), Positives = 143/356 (40%), Gaps = 72/356 (20%)
Query: 1 MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLS 60
MADQ P ISPL+ ++A G G V PLD VKVRLQ+Q PS+ +
Sbjct: 1 MADQ-PKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQ----------- 48
Query: 61 YTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGT 120
P ++GT D F K + EG
Sbjct: 49 ----------------------------------------PPMYSGTFDCFRKTLFREGI 68
Query: 121 RTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM-VAGALARLGTVTVI 179
L+ G+ A ++ P A+ F + K Y + AG L+ + T ++
Sbjct: 69 TGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIM 128
Query: 180 SPLELMRTKLQAQHVS----YRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWF 235
+P E ++ LQ Q S Y C + + G R ++ G T +RDVP S +Y+
Sbjct: 129 TPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFM 188
Query: 236 NYELVKSWLNGFRPK----DQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAME 291
YE +K N F P+ + S VAGGI+G + +P DV+K++ Q A
Sbjct: 189 TYEWLK---NIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGK- 244
Query: 292 AVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSF 347
+ + +LR + + G L+ GF +I+A P+ A +E F
Sbjct: 245 -------YPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKF 293
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/191 (23%), Positives = 81/191 (42%), Gaps = 14/191 (7%)
Query: 165 MVAGALARLGTVTVISPLELMRTKLQAQHVS-------YRELGACVRTAVAQGGWRSLWL 217
++AG + V V PL+ ++ +LQ Q S Y C R + + G L+
Sbjct: 14 LLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYR 73
Query: 218 GWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFD 277
G + P A+ +F + L K L P+D S F AG +SG + P +
Sbjct: 74 GMAAPIIGVTPMFAVCFFGFGLGKK-LQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGE 132
Query: 278 VVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIM 337
+K Q+ + E+ L +++ E G +G++ G + +++ P+ +
Sbjct: 133 RIKCLLQIQASSGESKYTGTLDC------AKKLYQEFGIRGIYKGTVLTLMRDVPASGMY 186
Query: 338 ISTYEFGKSFF 348
TYE+ K+ F
Sbjct: 187 FMTYEWLKNIF 197
Score = 35.0 bits (79), Expect = 0.10
Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 3/99 (3%)
Query: 258 SFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTK 317
+ +AGG G + P D VK + Q ++ P T+ R+ G
Sbjct: 13 NLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPG---QPPMYSGTFDCFRKTLFREGIT 69
Query: 318 GLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRL 356
GL+ G II P A+ + GK Q+ +D L
Sbjct: 70 GLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVL 108
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 92.8 bits (229), Expect = 4e-19
Identities = 87/345 (25%), Positives = 143/345 (41%), Gaps = 71/345 (20%)
Query: 13 QQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTG 72
+Q+VA G+ +V M PLDVVK R Q Q
Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQ------------------------------ 44
Query: 73 KCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLV 132
RCAT DP + +D+F I + EG + G+ ++
Sbjct: 45 --------------------RCAT---DPNSYKSLVDSFRMIFQMEGLFGFYKGILPPIL 81
Query: 133 MTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQ 192
P A+ F ++Q K L G S +AG + L V++P E+++ LQA
Sbjct: 82 AETPKRAVKFFTFEQYKKLL-GYVSLSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQAN 140
Query: 193 HVSYRELGACV---RTAVAQGGWRSLWLGWGPTAL--RDVPFSALYWFNYELVKSWLNGF 247
++ E + V R + + GW L G TA R F+ +Y+ Y VK+ +
Sbjct: 141 RNTFAEQPSTVGYARQIIKKEGWGLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMI--- 197
Query: 248 RPKDQTSV---GMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTW 304
P ++ + F G +SGT+A+V+ +PFDV K++ Q ++ + +
Sbjct: 198 -PVNKDPILEFWRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYR-----TCF 251
Query: 305 LLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQ 349
+ + E G L+ G LP+I++ P A+M+ YE+ S+ Q
Sbjct: 252 KTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQ 296
Score = 45.8 bits (107), Expect = 6e-05
Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 10/135 (7%)
Query: 156 ALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHV-----SYRELGACVRTAVAQG 210
+L + +VAG A L + ++ PL++++T+ Q Q SY+ L R
Sbjct: 8 SLVREASRQIVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQME 67
Query: 211 GWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGI-SGTVA 269
G + G P L + P A+ +F +E K L S ++F G+ SG
Sbjct: 68 GLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYV----SLSPALTFAIAGLGSGLTE 123
Query: 270 AVLTLPFDVVKTQRQ 284
A++ PF+VVK Q
Sbjct: 124 AIVVNPFEVVKVGLQ 138
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 90.9 bits (224), Expect = 2e-18
Identities = 70/239 (29%), Positives = 110/239 (46%), Gaps = 11/239 (4%)
Query: 113 KIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALAR 172
++ R EG R LW G + P +A+ AY + ++ ++AG+LA
Sbjct: 58 RVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAG 117
Query: 173 LGTVTVISPLELMRTKLQAQHV---SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 229
+ + V P +L++T+L Q++ SYR L T Q G+ +L+ G T + +PF
Sbjct: 118 MVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPF 177
Query: 230 SA---LYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVA 286
SA L + N E K W NG P+DQ S+ +F ++ V L+ PF+ VK + Q
Sbjct: 178 SAGSLLVYMNLE--KIW-NG--PRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQ 232
Query: 287 LGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGK 345
+ +H R+I G GL+ G ++K P IM ST+EF K
Sbjct: 233 SPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
Score = 39.7 bits (91), Expect = 0.004
Identities = 18/46 (39%), Positives = 28/46 (60%)
Query: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 149
F+G +D F +IV+ +G LW+GL A L+ VP I F+ ++ K
Sbjct: 246 FSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
Score = 31.6 bits (70), Expect = 1.2
Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 256 GMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESG 315
G + G++GT++ LT P ++ QV G + H W R+ G
Sbjct: 13 GQRLLCAGLAGTLSLSLTAPLELATVLAQV--GVVRG------HARGPWATGHRVWRAEG 64
Query: 316 TKGLFAGFLPRIIKAAPSCAIMISTY 341
+ L+ G ++ P A+ ++ Y
Sbjct: 65 LRALWKGNAVACLRLFPCSAVQLAAY 90
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 90.1 bits (222), Expect = 3e-18
Identities = 62/240 (25%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
Query: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM 165
G + F +++R G R+LW G ++ P +AI F AY+Q+K + T ++ +
Sbjct: 225 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL 284
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
VAG+LA + I P+E+++T++ + Y + C R +A+ G + + G+ P L
Sbjct: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNML 344
Query: 225 RDVPFSALYWFNYELVK-SWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
+P++ + YE +K +WL + V + G +S T + + P +V+T+
Sbjct: 345 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 404
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Q A V + L + I G GL+ G P +K P+ +I YE
Sbjct: 405 MQAQASIEGAPEV------TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
Score = 38.1 bits (87), Expect = 0.012
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 30/177 (16%)
Query: 188 KLQAQHV--SYRELGACVRTAVAQGGWRSL---------WLGWGPTAL----RDVPFSAL 232
++ AQ + S R+LG + A+ +S+ W W L ++P L
Sbjct: 97 RIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIIL 156
Query: 233 YWFNYELVKSWLNGFRPKDQT----SVGM---SFVAGGISGTVAAVLTLPFDVVKTQRQV 285
YW + + N P + T GM VAGG +G V+ T P D +K QV
Sbjct: 157 YWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQV 216
Query: 286 ALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
A R N + + + + R E G + L+ G ++K AP AI YE
Sbjct: 217 -----HASRSNNMGIVGGFTQMIR---EGGARSLWRGNGINVLKIAPESAIKFMAYE 265
Score = 31.2 bits (69), Expect = 1.5
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
F I+R EG L+ GL + +PA +I + Y+ LK L
Sbjct: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 90.1 bits (222), Expect = 3e-18
Identities = 62/240 (25%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
Query: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM 165
G + F +++R G R+LW G ++ P +AI F AY+Q+K + T ++ +
Sbjct: 259 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL 318
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
VAG+LA + I P+E+++T++ + Y + C R +A+ G + + G+ P L
Sbjct: 319 VAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNML 378
Query: 225 RDVPFSALYWFNYELVK-SWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
+P++ + YE +K +WL + V + G +S T + + P +V+T+
Sbjct: 379 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 438
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Q A V + L + I G GL+ G P +K P+ +I YE
Sbjct: 439 MQAQASIEGAPEV------TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 492
Score = 38.1 bits (87), Expect = 0.012
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 30/177 (16%)
Query: 188 KLQAQHV--SYRELGACVRTAVAQGGWRSL---------WLGWGPTAL----RDVPFSAL 232
++ AQ + S R+LG + A+ +S+ W W L ++P L
Sbjct: 131 RIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIIL 190
Query: 233 YWFNYELVKSWLNGFRPKDQT----SVGM---SFVAGGISGTVAAVLTLPFDVVKTQRQV 285
YW + + N P + T GM VAGG +G V+ T P D +K QV
Sbjct: 191 YWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQV 250
Query: 286 ALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
A R N + + + + R E G + L+ G ++K AP AI YE
Sbjct: 251 -----HASRSNNMGIVGGFTQMIR---EGGARSLWRGNGINVLKIAPESAIKFMAYE 299
Score = 31.2 bits (69), Expect = 1.5
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
F I+R EG L+ GL + +PA +I + Y+ LK L
Sbjct: 457 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 90.1 bits (222), Expect = 3e-18
Identities = 62/240 (25%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
Query: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM 165
G + F +++R G R+LW G ++ P +AI F AY+Q+K + T ++ +
Sbjct: 245 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL 304
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
VAG+LA + I P+E+++T++ + Y + C R +A+ G + + G+ P L
Sbjct: 305 VAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNML 364
Query: 225 RDVPFSALYWFNYELVK-SWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
+P++ + YE +K +WL + V + G +S T + + P +V+T+
Sbjct: 365 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 424
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Q A V + L + I G GL+ G P +K P+ +I YE
Sbjct: 425 MQAQASIEGAPEV------TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 478
Score = 38.1 bits (87), Expect = 0.012
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 30/177 (16%)
Query: 188 KLQAQHV--SYRELGACVRTAVAQGGWRSL---------WLGWGPTAL----RDVPFSAL 232
++ AQ + S R+LG + A+ +S+ W W L ++P L
Sbjct: 117 RIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIIL 176
Query: 233 YWFNYELVKSWLNGFRPKDQT----SVGM---SFVAGGISGTVAAVLTLPFDVVKTQRQV 285
YW + + N P + T GM VAGG +G V+ T P D +K QV
Sbjct: 177 YWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQV 236
Query: 286 ALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
A R N + + + + R E G + L+ G ++K AP AI YE
Sbjct: 237 -----HASRSNNMGIVGGFTQMIR---EGGARSLWRGNGINVLKIAPESAIKFMAYE 285
Score = 31.2 bits (69), Expect = 1.5
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
F I+R EG L+ GL + +PA +I + Y+ LK L
Sbjct: 443 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 484
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 90.1 bits (222), Expect = 3e-18
Identities = 62/240 (25%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
Query: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM 165
G + F +++R G R+LW G ++ P +AI F AY+Q+K + T ++ +
Sbjct: 225 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL 284
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
VAG+LA + I P+E+++T++ + Y + C R +A+ G + + G+ P L
Sbjct: 285 VAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNML 344
Query: 225 RDVPFSALYWFNYELVK-SWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
+P++ + YE +K +WL + V + G +S T + + P +V+T+
Sbjct: 345 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 404
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Q A V + L + I G GL+ G P +K P+ +I YE
Sbjct: 405 MQAQASIEGAPEV------TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 458
Score = 38.1 bits (87), Expect = 0.012
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 30/177 (16%)
Query: 188 KLQAQHV--SYRELGACVRTAVAQGGWRSL---------WLGWGPTAL----RDVPFSAL 232
++ AQ + S R+LG + A+ +S+ W W L ++P L
Sbjct: 97 RIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIIL 156
Query: 233 YWFNYELVKSWLNGFRPKDQT----SVGM---SFVAGGISGTVAAVLTLPFDVVKTQRQV 285
YW + + N P + T GM VAGG +G V+ T P D +K QV
Sbjct: 157 YWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQV 216
Query: 286 ALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
A R N + + + + R E G + L+ G ++K AP AI YE
Sbjct: 217 -----HASRSNNMGIVGGFTQMIR---EGGARSLWRGNGINVLKIAPESAIKFMAYE 265
Score = 31.2 bits (69), Expect = 1.5
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
F I+R EG L+ GL + +PA +I + Y+ LK L
Sbjct: 423 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 90.1 bits (222), Expect = 3e-18
Identities = 62/240 (25%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
Query: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM 165
G + F +++R G R+LW G ++ P +AI F AY+Q+K + T ++ +
Sbjct: 122 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL 181
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
VAG+LA + I P+E+++T++ + Y + C R +A+ G + + G+ P L
Sbjct: 182 VAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNML 241
Query: 225 RDVPFSALYWFNYELVK-SWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
+P++ + YE +K +WL + V + G +S T + + P +V+T+
Sbjct: 242 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 301
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Q A V + L + I G GL+ G P +K P+ +I YE
Sbjct: 302 MQAQASIEGAPEV------TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 355
Score = 37.4 bits (85), Expect = 0.021
Identities = 36/126 (28%), Positives = 53/126 (42%), Gaps = 15/126 (11%)
Query: 224 LRDVPFSALYWFNYELVKSWLNGFRPKDQT----SVGM---SFVAGGISGTVAAVLTLPF 276
+ ++P LYW + + N P + T GM VAGG +G V+ T P
Sbjct: 45 VENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPL 104
Query: 277 DVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAI 336
D +K QV A R N + + + + R E G + L+ G ++K AP AI
Sbjct: 105 DRLKVLMQV-----HASRSNNMGIVGGFTQMIR---EGGARSLWRGNGINVLKIAPESAI 156
Query: 337 MISTYE 342
YE
Sbjct: 157 KFMAYE 162
Score = 31.2 bits (69), Expect = 1.5
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
F I+R EG L+ GL + +PA +I + Y+ LK L
Sbjct: 320 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 361
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 90.1 bits (222), Expect = 3e-18
Identities = 62/240 (25%), Positives = 111/240 (46%), Gaps = 9/240 (3%)
Query: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM 165
G + F +++R G R+LW G ++ P +AI F AY+Q+K + T ++ +
Sbjct: 259 GIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERL 318
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTAL 224
VAG+LA + I P+E+++T++ + Y + C R +A+ G + + G+ P L
Sbjct: 319 VAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNML 378
Query: 225 RDVPFSALYWFNYELVK-SWLNGFRPKD-QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQ 282
+P++ + YE +K +WL + V + G +S T + + P +V+T+
Sbjct: 379 GIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTR 438
Query: 283 RQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
Q A V + L + I G GL+ G P +K P+ +I YE
Sbjct: 439 MQAQASIEGAPEV------TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYE 492
Score = 38.1 bits (87), Expect = 0.012
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 30/177 (16%)
Query: 188 KLQAQHV--SYRELGACVRTAVAQGGWRSL---------WLGWGPTAL----RDVPFSAL 232
++ AQ + S R+LG + A+ +S+ W W L ++P L
Sbjct: 131 RIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIIL 190
Query: 233 YWFNYELVKSWLNGFRPKDQT----SVGM---SFVAGGISGTVAAVLTLPFDVVKTQRQV 285
YW + + N P + T GM VAGG +G V+ T P D +K QV
Sbjct: 191 YWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQV 250
Query: 286 ALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
A R N + + + + R E G + L+ G ++K AP AI YE
Sbjct: 251 -----HASRSNNMGIVGGFTQMIR---EGGARSLWRGNGINVLKIAPESAIKFMAYE 299
Score = 31.2 bits (69), Expect = 1.5
Identities = 15/42 (35%), Positives = 22/42 (52%)
Query: 111 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFL 152
F I+R EG L+ GL + +PA +I + Y+ LK L
Sbjct: 457 FKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
>gi|45237193 solute carrier family 25, member 44 isoform 1 [Homo
sapiens]
Length = 314
Score = 88.2 bits (217), Expect = 1e-17
Identities = 67/258 (25%), Positives = 114/258 (44%), Gaps = 33/258 (12%)
Query: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 163
+ GT DAF+KI+R +G L+ G T+ + Y T Y+ + F+ + S+
Sbjct: 54 YHGTFDAFIKILRADGITGLYRGFLVN-TFTLISGQCYVTTYELTRKFVADYS-QSNTVK 111
Query: 164 PMVAGALARLGTVTVISPLELMRTKLQAQH-------------------VSYRELGACVR 204
+VAG A L ++ P++++ L Q V++ + +R
Sbjct: 112 SLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDIIR 171
Query: 205 TAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGI 264
+ G R + G+ + L +P SA++W Y L+ PK+ + V+G +
Sbjct: 172 QILQADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGPL 231
Query: 265 SGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFL 324
+ A++LT P DV++T+ QV +S L R++ AE G GL G
Sbjct: 232 AAATASILTNPMDVIRTRVQVE------------GKNSIILTFRQLMAEEGPWGLMKGLS 279
Query: 325 PRIIKAAPSCAIMISTYE 342
RII A PS +++ YE
Sbjct: 280 ARIISATPSTIVIVVGYE 297
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 85.9 bits (211), Expect = 5e-17
Identities = 89/347 (25%), Positives = 139/347 (40%), Gaps = 66/347 (19%)
Query: 12 LQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQST 71
L + A G G V ++ PL+VVK RLQS S T S +Q
Sbjct: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSS-----------------SVTLYISEVQLN 49
Query: 72 GKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL 131
N V+ P G + I+ EG R+L+ GL L
Sbjct: 50 TMAGASVNRVVSP---------------------GPLHCLKVILEKEGPRSLFRGLGPNL 88
Query: 132 VMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQ- 190
V P+ AIYF AY K L M++ A+A +T +P+ L++T+LQ
Sbjct: 89 VGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQL 148
Query: 191 -AQHVSYRELGA--CVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGF 247
A++ R +GA CVR G + + G + + + +++ YE +K L +
Sbjct: 149 DARNRGERRMGAFECVRKVYQTDGLKGFYRGMS-ASYAGISETVIHFVIYESIKQKLLEY 207
Query: 248 R-----PKDQTS-------VGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRV 295
+ D+ S VGM +A S T A + P +VV+T+ +R
Sbjct: 208 KTASTMENDEESVKEASDFVGM-MLAAATSKTCATTIAYPHEVVRTR----------LRE 256
Query: 296 NPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
S + L + E G L+ G +++ P+ AIM++TYE
Sbjct: 257 EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 303
Score = 56.6 bits (135), Expect = 3e-08
Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 14/157 (8%)
Query: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTS--- 159
R G + K+ + +G + + G+ A+ + T I+F Y+ +K L S
Sbjct: 156 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME 214
Query: 160 ----------DLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQ 209
D M+A A ++ T+ P E++RT+L+ + YR + V +
Sbjct: 215 NDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQE 274
Query: 210 GGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNG 246
G+ SL+ G +R +P +A+ YELV LNG
Sbjct: 275 EGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 311
Score = 31.2 bits (69), Expect = 1.5
Identities = 16/56 (28%), Positives = 27/56 (48%)
Query: 99 QDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCG 154
++ T++ +V+ EG +L+ GL LV +P TAI Y+ + L G
Sbjct: 256 EEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 311
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 82.8 bits (203), Expect = 4e-16
Identities = 69/247 (27%), Positives = 108/247 (43%), Gaps = 12/247 (4%)
Query: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYA 163
+ + D F K++R+EG L+ GL L+ P AI T D ++ R + L A
Sbjct: 369 YKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPA 428
Query: 164 PMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTA 223
++AG A V +PLE+++ +LQ + G L+ G
Sbjct: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACF 488
Query: 224 LRDVPFSALYWFNYELVKSWLNGFRPKDQTSVG--MSFVAGGISGTVAAVLTLPFDVVKT 281
LRD+PFSA+Y+ Y K L + VG AG ++G AA L P DV+KT
Sbjct: 489 LRDIPFSAIYFPVYAHCKLLL----ADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKT 544
Query: 282 QRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTY 341
+ QVA A + + R+I E G + G R+ +++P + + TY
Sbjct: 545 RLQVAARAGQTTYSGVID------CFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTY 598
Query: 342 EFGKSFF 348
E + +F
Sbjct: 599 ELLQRWF 605
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Query: 259 FVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKG 318
F G ++G V A P D+VKT+ Q G+ V L +++ +++ G G
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVV--GELMYKNSFDCFKKVLRYEGFFG 387
Query: 319 LFAGFLPRIIKAAPSCAIMISTYEFGKSFFQR 350
L+ G +P++I AP AI ++ +F + F R
Sbjct: 388 LYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTR 419
Score = 35.8 bits (81), Expect = 0.061
Identities = 15/48 (31%), Positives = 24/48 (50%)
Query: 102 TRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 149
T ++G +D F KI+R EG W G A + + P + Y+ L+
Sbjct: 555 TTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQ 602
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 82.0 bits (201), Expect = 7e-16
Identities = 70/260 (26%), Positives = 120/260 (46%), Gaps = 22/260 (8%)
Query: 106 GTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPM 165
G A + + EG L+ G A ++ P AI F A++ K + + S +
Sbjct: 75 GVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRL 134
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQ---HVSYRELGACVRTAVA-QGGWRSLWLGWGP 221
+AG++A + V PL+++R +L Q SY + +T A +GG+ + G P
Sbjct: 135 MAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMP 194
Query: 222 TALRDVPFSALYWFNYELVKS-------WLNGFRPKDQTSV-----GMSFVAGGISGTVA 269
T L P++ + +F + +KS L G D +V ++ + GG++G +A
Sbjct: 195 TILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIA 254
Query: 270 AVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESG-TKGLFAGFLPRII 328
++ PFDV T+R++ LG + L + T ++ + G KGL+ G I
Sbjct: 255 QTISYPFDV--TRRRMQLGTVLPEFEKCLTMRDT---MKYVYGHHGIRKGLYRGLSLNYI 309
Query: 329 KAAPSCAIMISTYEFGKSFF 348
+ PS A+ +TYE K FF
Sbjct: 310 RCIPSQAVAFTTYELMKQFF 329
Score = 58.2 bits (139), Expect = 1e-08
Identities = 47/188 (25%), Positives = 84/188 (44%), Gaps = 20/188 (10%)
Query: 166 VAGALARLGTVTVISPLELMRTKLQAQHVSYRELG--ACVRTAVAQGGWRSLWLGWGPTA 223
+AG +A T ++PL+ ++ LQA + Y+ LG + +R + G+ L+ G G
Sbjct: 41 LAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMM 100
Query: 224 LRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMS-----FVAGGISGTVAAVLTLPFDV 278
+R P+ A+ + +E K+ + T +G+S +AG ++G A + T P D+
Sbjct: 101 IRIFPYGAIQFMAFEHYKTLIT-------TKLGISGHVHRLMAGSMAGMTAVICTYPLDM 153
Query: 279 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 338
V+ + + E +H T E G G + G +P I+ AP +
Sbjct: 154 VRVRLAFQVKG-EHSYTGIIHAFKT-----IYAKEGGFFGFYRGLMPTILGMAPYAGVSF 207
Query: 339 STYEFGKS 346
T+ KS
Sbjct: 208 FTFGTLKS 215
Score = 32.7 bits (73), Expect = 0.52
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%)
Query: 258 SFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTK 317
SF+AGGI+G A P D VK ++A + H+ + LR + + G
Sbjct: 39 SFLAGGIAGCCAKTTVAPLDRVKV-------LLQAHNHHYKHL-GVFSALRAVPQKEGFL 90
Query: 318 GLFAGFLPRIIKAAPSCAIMISTYEFGKS 346
GL+ G +I+ P AI +E K+
Sbjct: 91 GLYKGNGAMMIRIFPYGAIQFMAFEHYKT 119
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 80.5 bits (197), Expect = 2e-15
Identities = 89/347 (25%), Positives = 138/347 (39%), Gaps = 67/347 (19%)
Query: 12 LQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQST 71
L + A G G V ++ PL+VVK RLQS S T S +Q
Sbjct: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSS-----------------SVTLYISEVQLN 49
Query: 72 GKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL 131
N V+ P G + I+ EG R+L+ GL L
Sbjct: 50 TMAGASVNRVVSP---------------------GPLHCLKVILEKEGPRSLFRGLGPNL 88
Query: 132 VMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQ- 190
V P+ AIYF AY K L M++ A+A +T +P+ L++T+LQ
Sbjct: 89 VGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQL 148
Query: 191 -AQHVSYRELGA--CVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGF 247
A++ R +GA CVR G + + G + + + +++ YE +K L +
Sbjct: 149 DARNRGERRMGAFECVRKVYQTDGLKGFYRGMS-ASYAGISETVIHFVIYESIKQKLLEY 207
Query: 248 R-----PKDQTS-------VGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRV 295
+ D+ S VGM +A S T A + P VV+T+ +R
Sbjct: 208 KTASTMENDEESVKEASDFVGM-MLAAATSKTCATTIAYP-HVVRTR----------LRE 255
Query: 296 NPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
S + L + E G L+ G +++ P+ AIM++TYE
Sbjct: 256 EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTS--- 159
R G + K+ + +G + + G+ A+ + T I+F Y+ +K L S
Sbjct: 156 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME 214
Query: 160 ----------DLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQ 209
D M+A A ++ T+ P ++RT+L+ + YR + V +
Sbjct: 215 NDEESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKYRSFFQTLSLLVQE 273
Query: 210 GGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNG 246
G+ SL+ G +R +P +A+ YELV LNG
Sbjct: 274 EGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 310
Score = 31.2 bits (69), Expect = 1.5
Identities = 16/56 (28%), Positives = 27/56 (48%)
Query: 99 QDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCG 154
++ T++ +V+ EG +L+ GL LV +P TAI Y+ + L G
Sbjct: 255 EEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 310
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 77.4 bits (189), Expect = 2e-14
Identities = 63/242 (26%), Positives = 108/242 (44%), Gaps = 15/242 (6%)
Query: 117 HEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLC------GRALTSDLYAPMVAGAL 170
+EG +LW G AT+V VP AI F+A+++ K L G AL + + AGAL
Sbjct: 83 NEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPP--WPRLFAGAL 140
Query: 171 ARLGTVTVISPLELMRTKLQAQHVS-YRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 229
A ++ PL+L+R ++ Y + + G ++L+ G+ PT L +P+
Sbjct: 141 AGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPY 200
Query: 230 SALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGA 289
+ L +F YE +KS + + Q + G +G + + P DVV+ + Q A G
Sbjct: 201 AGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTA-GV 259
Query: 290 MEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQ 349
R + L +R E +GL+ G +K + I +T++ + +
Sbjct: 260 TGYPRASIART-----LRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIMLR 314
Query: 350 RL 351
L
Sbjct: 315 HL 316
Score = 71.6 bits (174), Expect = 1e-12
Identities = 65/208 (31%), Positives = 97/208 (46%), Gaps = 23/208 (11%)
Query: 155 RALTSDLYAPMVAGALARLGTVTVISPLELMRTKL----QAQHVSYRELGACVRTAVAQG 210
R + S L +AGALA+ T ++PL+ RTK+ ++ S +E +
Sbjct: 31 RQVLSSLLPGALAGALAK----TAVAPLD--RTKIIFQVSSKRFSAKEAFRVLYYTYLNE 84
Query: 211 GWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLN---GFRPKDQTSVGMSFVAGGISGT 267
G+ SLW G T +R VP++A+ + +E K L GFR + F AG ++GT
Sbjct: 85 GFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLF-AGALAGT 143
Query: 268 VAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRI 327
AA LT P D+V+ + V M + N HV RI E G K L+ GF+P +
Sbjct: 144 TAASLTYPLDLVRARMAVTPKEMYS---NIFHV------FIRISREEGLKTLYHGFMPTV 194
Query: 328 IKAAPSCAIMISTYEFGKSFFQRLNQDR 355
+ P + TYE KS + + R
Sbjct: 195 LGVIPYAGLSFFTYETLKSLHREYSGRR 222
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 14/134 (10%)
Query: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAF---LCGRALTSD 160
++ F++I R EG +TL+ G T++ +P + F Y+ LK+ GR
Sbjct: 167 YSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYP 226
Query: 161 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRT--------AVAQGGW 212
+ M+ GA A L + PL+++R ++Q V+ + RT +G +
Sbjct: 227 -FERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLY 285
Query: 213 RSLWLGW--GPTAL 224
+ L + W GP A+
Sbjct: 286 KGLSMNWVKGPIAV 299
>gi|14150082 mitochondrial carrier protein MGC4399 [Homo sapiens]
Length = 321
Score = 77.0 bits (188), Expect = 2e-14
Identities = 76/344 (22%), Positives = 139/344 (40%), Gaps = 58/344 (16%)
Query: 12 LQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQST 71
L + A G G V ++F PL+V+K RLQS R ++ + P L ++S
Sbjct: 12 LLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGA--------- 62
Query: 72 GKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL 131
G++ P + P G I+ EG ++L+ GL L
Sbjct: 63 --------GMVRPTSVTP----------------GLFQVLKSILEKEGPKSLFRGLGPNL 98
Query: 132 VMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQA 191
V P+ A+YF Y + K G + + + + A T ++++P+ +++T++Q
Sbjct: 99 VGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQL 158
Query: 192 QHV--SYRELGA--CVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWL--- 244
+ +++ C R G R + G + + + + + YE +K +L
Sbjct: 159 EQKVRGSKQMNTLQCARYVYQTEGIRGFYRGL-TASYAGISETIICFAIYESLKKYLKEA 217
Query: 245 ------NGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPL 298
NG K+ TS A +S A+ + P +V++T+ +R
Sbjct: 218 PLASSANGTE-KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTR----------LREEGT 266
Query: 299 HVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
S R + E G + G ++I+ P+ AI++STYE
Sbjct: 267 KYKSFVQTARLVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYE 310
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 15/103 (14%)
Query: 261 AGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDS---------------TWL 305
AGG GTV A+ T P +V+KT+ Q + A+ V +H+ + +
Sbjct: 17 AGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSVTPGLFQ 76
Query: 306 LLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFF 348
+L+ I + G K LF G P ++ APS A+ + Y K F
Sbjct: 77 VLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQF 119
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 76.3 bits (186), Expect = 4e-14
Identities = 76/336 (22%), Positives = 127/336 (37%), Gaps = 66/336 (19%)
Query: 14 QMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTGK 73
+ + +GT A + L PLD KVRLQ Q S +S
Sbjct: 16 KFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATAS------------------- 56
Query: 74 CLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVM 133
++ G M + +VR EG R+L++GL A L
Sbjct: 57 ----------------------------AQYRGVMGTILTMVRTEGPRSLYNGLVAGLQR 88
Query: 134 TVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQH 193
+ ++ YD +K F + + + + ++AG+ V V P ++++ + QAQ
Sbjct: 89 QMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQA 148
Query: 194 VS-----YRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFR 248
+ Y+ +T + G+R LW G P R+ + Y+L+K L +
Sbjct: 149 RAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDAL--LK 206
Query: 249 PKDQT-SVGMSFVAGGISGTVAAVLTLPFDVVKTQ-RQVALGAMEAVRVNPLHVDSTWLL 306
T + F + +G V+ P DVVKT+ ALG + H T L
Sbjct: 207 ANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAG----HCALTML- 261
Query: 307 LRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 342
+ G + + GF+P ++ +M TYE
Sbjct: 262 -----QKEGPRAFYKGFMPSFLRLGSWNVVMFVTYE 292
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
Query: 103 RFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK-AFLCGRALTSDL 161
R+ T++A+ I R EG R LW G + YD +K A L +T DL
Sbjct: 155 RYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDL 214
Query: 162 YAPMVAGALARLGTVTVISPLELMRTKLQAQHVS-YRELGACVRTAVAQGGWRSLWLGWG 220
+ A T + SP+++++T+ + Y G C T + + G R+ + G+
Sbjct: 215 PCHFTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFM 274
Query: 221 PTALRDVPFSALYWFNYELVK 241
P+ LR ++ + + YE +K
Sbjct: 275 PSFLRLGSWNVVMFVTYEQLK 295
Score = 52.0 bits (123), Expect = 8e-07
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 20/184 (10%)
Query: 181 PLELMRTKLQAQHVS-----------YRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 229
PL+ + +LQ Q S YR + + T V G RSL+ G R + F
Sbjct: 33 PLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSF 92
Query: 230 SALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGA 289
+++ Y+ VK + + + S+G +AG +G +A + P DVVK + Q A
Sbjct: 93 ASVRIGLYDSVKQFYT--KGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARA 150
Query: 290 MEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIK-AAPSCAIMISTYEFGKSFF 348
R ST + I E G +GL+ G P + + A +CA ++ TY+ K
Sbjct: 151 GGGRRYQ-----STVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELV-TYDLIKDAL 204
Query: 349 QRLN 352
+ N
Sbjct: 205 LKAN 208
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 75.9 bits (185), Expect = 5e-14
Identities = 76/352 (21%), Positives = 135/352 (38%), Gaps = 64/352 (18%)
Query: 13 QQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTG 72
Q VA +VT ++P DV+K+R Q Q ++
Sbjct: 17 QVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSR------------------------ 52
Query: 73 KCLLYCNGVLEPLYLCPNGARCATWFQDPT-RFTGTMDAFVKIVRHEGTRTLWSGLPATL 131
DP+ ++ G + A +I++ EG W G
Sbjct: 53 --------------------------SDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQ 86
Query: 132 VMTVPATAIYFTAYDQLKAFLCGRAL--TSDLYAPMVAGALARLGTVTVISPLELMRTKL 189
++++ A+ F +++ L + ++ + V G LA + P++++RT+
Sbjct: 87 ILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRF 146
Query: 190 QAQHVS--YRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVK---SWL 244
AQ Y L V T G + + G PT + P++ L + Y +K W
Sbjct: 147 AAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWA 206
Query: 245 NGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTW 304
K ++ + + G +G ++ LT P D+ K + QV G E R V
Sbjct: 207 IPAEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQV--GGFEHARAAFGQVRRYK 263
Query: 305 LLL---RRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQ 353
L+ +++ + G G F G P ++KAA S M +YEF + F +N+
Sbjct: 264 GLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCMNR 315
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,857,574
Number of Sequences: 37866
Number of extensions: 536994
Number of successful extensions: 1665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1060
Number of HSP's gapped (non-prelim): 312
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.