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Search of human proteins with 219521928
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like
isoform 1 [Homo sapiens]
(1054 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like i... 2140 0.0
gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like is... 1967 0.0
gi|190014623 DIS3 mitotic control isoform a [Homo sapiens] 556 e-158
gi|190014625 DIS3 mitotic control isoform b [Homo sapiens] 510 e-144
gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2... 284 3e-76
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 130 9e-30
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ... 130 9e-30
gi|224809295 xeroderma pigmentosum, complementation group C isof... 32 2.4
gi|126032348 hect domain and RLD 2 [Homo sapiens] 32 3.2
gi|239740946 PREDICTED: hypothetical protein XP_002344104 isofor... 32 3.2
gi|239740944 PREDICTED: hypothetical protein XP_002344105 isofor... 32 3.2
gi|239740942 PREDICTED: hypothetical protein XP_002344106 isofor... 32 3.2
gi|32698714 hypothetical protein LOC284058 [Homo sapiens] 32 3.2
gi|126032345 sterile alpha motif domain containing 3 isoform b [... 32 4.1
gi|126032305 sterile alpha motif domain containing 3 isoform a [... 32 4.1
gi|165905601 proline-serine-threonine phosphatase interacting pr... 31 5.4
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 31 7.0
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 31 7.0
gi|170016081 XRP2 protein [Homo sapiens] 30 9.2
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 30 9.2
gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 30 9.2
gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromoso... 30 9.2
>gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like
isoform 1 [Homo sapiens]
Length = 1054
Score = 2140 bits (5544), Expect = 0.0
Identities = 1054/1054 (100%), Positives = 1054/1054 (100%)
Query: 1 MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVI 60
MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVI
Sbjct: 1 MLQKREKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVI 60
Query: 61 PDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANE 120
PDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANE
Sbjct: 61 PDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANE 120
Query: 121 FQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGV 180
FQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGV
Sbjct: 121 FQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGV 180
Query: 181 FVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKS 240
FVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKS
Sbjct: 181 FVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKS 240
Query: 241 GRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLP 300
GRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLP
Sbjct: 241 GRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLP 300
Query: 301 KNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGK 360
KNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGK
Sbjct: 301 KNEWKGRTVALCENDCDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGK 360
Query: 361 NAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDL 420
NAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDL
Sbjct: 361 NAQKILVTPWDYRIPKIRISTQQAETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDL 420
Query: 421 EGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPK 480
EGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPK
Sbjct: 421 EGEIATILVENSISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPK 480
Query: 481 GCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLP 540
GCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLP
Sbjct: 481 GCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLP 540
Query: 541 SVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGN 600
SVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGN
Sbjct: 541 SVLSADLCSLLGGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGN 600
Query: 601 LSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQL 660
LSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQL
Sbjct: 601 LSVVDDIPEFKDLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQL 660
Query: 661 DDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSEL 720
DDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSEL
Sbjct: 661 DDKKNIHDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSEL 720
Query: 721 RECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEE 780
RECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEE
Sbjct: 721 RECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEE 780
Query: 781 EFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHI 840
EFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHI
Sbjct: 781 EFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHI 840
Query: 841 NNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGA 900
NNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGA
Sbjct: 841 NNRNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGA 900
Query: 901 AYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQAS 960
AYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQAS
Sbjct: 901 AYLKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQAS 960
Query: 961 RCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQE 1020
RCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQE
Sbjct: 961 RCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQE 1020
Query: 1021 EYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI 1054
EYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI
Sbjct: 1021 EYQEYRQTKGRSLYTLLEEIRDLALLDVSNNYGI 1054
>gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like isoform
2 [Homo sapiens]
Length = 971
Score = 1967 bits (5095), Expect = 0.0
Identities = 971/971 (100%), Positives = 971/971 (100%)
Query: 84 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI 143
MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI
Sbjct: 1 MQTACQAVQHQRGRRQYNKLRNLLKDARHDCILFANEFQQCCYLPRERGESMEKWQTRSI 60
Query: 144 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC 203
YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC
Sbjct: 61 YNAAVWYYHHCQDRMPIVMVTEDEEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELC 120
Query: 204 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL 263
DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL
Sbjct: 121 DSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRL 180
Query: 264 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE 323
QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE
Sbjct: 181 QGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGE 240
Query: 324 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ 383
SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ
Sbjct: 241 SPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQ 300
Query: 384 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM 443
AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM
Sbjct: 301 AETLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQM 360
Query: 444 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV 503
CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV
Sbjct: 361 CEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGV 420
Query: 504 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW 563
HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW
Sbjct: 421 HIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMW 480
Query: 564 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 623
ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE
Sbjct: 481 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 540
Query: 624 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 683
ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE
Sbjct: 541 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 600
Query: 684 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL 743
CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL
Sbjct: 601 CMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSL 660
Query: 744 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS 803
DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS
Sbjct: 661 DNANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYS 720
Query: 804 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF 863
DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF
Sbjct: 721 DIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYF 780
Query: 864 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP 923
KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP
Sbjct: 781 KDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKP 840
Query: 924 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE 983
GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE
Sbjct: 841 GSLQRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEIISNKPYKIPNTE 900
Query: 984 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL 1043
LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL
Sbjct: 901 LIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDL 960
Query: 1044 ALLDVSNNYGI 1054
ALLDVSNNYGI
Sbjct: 961 ALLDVSNNYGI 971
>gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]
Length = 958
Score = 556 bits (1433), Expect = e-158
Identities = 359/1006 (35%), Positives = 549/1006 (54%), Gaps = 118/1006 (11%)
Query: 5 REKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAAC--SHDGKLL-------SSDV 55
+ K L +T G ++IVREHYLR + C +P C AAC +H+G L +S V
Sbjct: 3 KSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGC---AACGGAHEGPALEPQPQDPASSV 59
Query: 56 T---HYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARH 112
HY++PD V+ +++LE P ++ +I +QT Q V++ R Y ++R++ +
Sbjct: 60 CPQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRN-RSAPVYKRIRDVTNNQEK 118
Query: 113 DCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQ-----DRMPIVMVTED- 166
F NE + Y+ +E+GE+ R+I AA WY H + +++ ++ +T D
Sbjct: 119 HFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDR 178
Query: 167 ---EEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGK 223
E+AI+ EG+ T + Y+ + L A EL D + + E ES
Sbjct: 179 RNKEKAIE------EGIPAFTCEEYVKS----LTANPELIDRL--ACLSEEGNEIESGKI 226
Query: 224 EYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMK 283
+ EHLPL L+ GIKSG Y+QG ++ +EA V + G D++ +I++ G+K
Sbjct: 227 IFSEHLPLSKLQQGIKSGTYLQGTFRASREN-YLEATVWIHG----DNEENKEIILQGLK 281
Query: 284 ARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEP-------------MP 330
NR++H D+V VELLPK++W + + ++ ++ E E P
Sbjct: 282 HLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKP 341
Query: 331 TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDF 390
TGRVVGI+++NWR Y SK ++ K +++ L TP D RIP+IRI T+QA TL+
Sbjct: 342 TGRVVGIIKRNWRPYCGML-SKSDI----KESRRHLFTPADKRIPRIRIETRQASTLEGR 396
Query: 391 RVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNT 450
R++V ID W S YPNGHFVR LG +G+ E E +L+E+ + PFS+A + +P
Sbjct: 397 RIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP--- 453
Query: 451 PESPWKVSPEEEQKRKDLRKSHL-VFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVT 509
+ PW ++ ++ + R+DLR HL + S+DP GC D+DD L R L NGNLE+GVHIADV+
Sbjct: 454 -KMPWSITEKDMKNREDLR--HLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVS 510
Query: 510 HFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKAS 569
HF+ P + +D E+ R TT YL ++R DM+P +LS++LCSL VDR A S +WE++ +
Sbjct: 511 HFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNH-N 569
Query: 570 YEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAI 629
EI K + +++I S L Y AQ +D + ++ DDI ++
Sbjct: 570 AEILKTKFTKSVINSKASLTYAEAQLRID-SANMNDDI------------------TTSL 610
Query: 630 GKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHET---VAECMI 686
L +A+ ++ +R GAL L EV +D + HD I Q E+ ET V E M+
Sbjct: 611 RGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSE--THDPIDLQTKELRETNSMVEEFML 668
Query: 687 LANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNA 746
LAN VAKKI E F ALLR+HP P + L + A+++ I T + K+LA+SLD A
Sbjct: 669 LANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQA 728
Query: 747 NDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIV 806
P P +N LLR +AT+ M A+YF +G + +FHHYGLA YTHFTSPIRRY+D++
Sbjct: 729 ESPTFPYLNTLLRILATRCMMQAVYFCSG--MDNDFHHYGLASPIYTHFTSPIRRYADVI 786
Query: 807 VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDK 866
VHRLL AI D L L ++C+++N R++ AQ++Q+ S ++FK K
Sbjct: 787 VHRLLAVAIGADCTYP---ELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSK 843
Query: 867 DPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSL 926
+EE I +R N +++ IP++G++G + + KD KP
Sbjct: 844 GIVSEE-----AYILFVRKNAIVVLIPKYGLEGTVFFEEKD--------------KPNPQ 884
Query: 927 QRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEII 972
+ ++I S E FH+FD V V+I + +S IR+ ++
Sbjct: 885 LIYDDEIPSLKI--EDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLV 928
>gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]
Length = 928
Score = 510 bits (1314), Expect = e-144
Identities = 348/1006 (34%), Positives = 527/1006 (52%), Gaps = 148/1006 (14%)
Query: 5 REKVLLLRTFQGRTLRIVREHYLRPCVPCHSPLCPQPAAC--SHDGKLL-------SSDV 55
+ K L +T G ++IVREHYLR + C +P C AAC +H+G L +S V
Sbjct: 3 KSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGC---AACGGAHEGPALEPQPQDPASSV 59
Query: 56 T---HYVIPDWKVVQDYLEILEFPELKGIIFMQTACQAVQHQRGRRQYNKLRNLLKDARH 112
HY++PD V+ + P + +L L+
Sbjct: 60 CPQPHYLLPDTNVLLHQIVSAWRPGTWASVASSL---------------RLPGSLET--- 101
Query: 113 DCILFANEFQQCCYLPRERGESMEKWQTRSIYNAAVWYYHHCQ-----DRMPIVMVTED- 166
Y+ +E+GE+ R+I AA WY H + +++ ++ +T D
Sbjct: 102 -------------YVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDR 148
Query: 167 ---EEAIQQYGSETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGK 223
E+AI+ EG+ T + Y+ + L A EL D + + E ES
Sbjct: 149 RNKEKAIE------EGIPAFTCEEYVKS----LTANPELIDRL--ACLSEEGNEIESGKI 196
Query: 224 EYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASSKDSDLVSDILIHGMK 283
+ EHLPL L+ GIKSG Y+QG ++ +EA V + G D++ +I++ G+K
Sbjct: 197 IFSEHLPLSKLQQGIKSGTYLQGTFRASREN-YLEATVWIHG----DNEENKEIILQGLK 251
Query: 284 ARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGESPSEP-------------MP 330
NR++H D+V VELLPK++W + + ++ ++ E E P
Sbjct: 252 HLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKP 311
Query: 331 TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAETLQDF 390
TGRVVGI+++NWR Y SK ++ K +++ L TP D RIP+IRI T+QA TL+
Sbjct: 312 TGRVVGIIKRNWRPYCGML-SKSDI----KESRRHLFTPADKRIPRIRIETRQASTLEGR 366
Query: 391 RVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCEMPVNT 450
R++V ID W S YPNGHFVR LG +G+ E E +L+E+ + PFS+A + +P
Sbjct: 367 RIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLP--- 423
Query: 451 PESPWKVSPEEEQKRKDLRKSHL-VFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVT 509
+ PW ++ ++ + R+DLR HL + S+DP GC D+DD L R L NGNLE+GVHIADV+
Sbjct: 424 -KMPWSITEKDMKNREDLR--HLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVS 480
Query: 510 HFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLLGGVDRYAVSIMWELDKAS 569
HF+ P + +D E+ R TT YL ++R DM+P +LS++LCSL VDR A S +WE++ +
Sbjct: 481 HFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNH-N 539
Query: 570 YEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEELVWAI 629
EI K + +++I S L Y AQ +D + ++ DDI ++
Sbjct: 540 AEILKTKFTKSVINSKASLTYAEAQLRID-SANMNDDI------------------TTSL 580
Query: 630 GKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHET---VAECMI 686
L +A+ ++ +R GAL L EV +D + HD I Q E+ ET V E M+
Sbjct: 581 RGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSE--THDPIDLQTKELRETNSMVEEFML 638
Query: 687 LANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDNA 746
LAN VAKKI E F ALLR+HP P + L + A+++ I T + K+LA+SLD A
Sbjct: 639 LANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQA 698
Query: 747 NDPHDPIVNRLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIV 806
P P +N LLR +AT+ M A+YF +G + +FHHYGLA YTHFTSPIRRY+D++
Sbjct: 699 ESPTFPYLNTLLRILATRCMMQAVYFCSG--MDNDFHHYGLASPIYTHFTSPIRRYADVI 756
Query: 807 VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHSQKQSTELFQCMYFKDK 866
VHRLL AI D L L ++C+++N R++ AQ++Q+ S ++FK K
Sbjct: 757 VHRLLAVAIGADCTYP---ELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSK 813
Query: 867 DPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAYLKNKDGLVISCGPDSCSEWKPGSL 926
+EE I +R N +++ IP++G++G + + KD KP
Sbjct: 814 GIVSEE-----AYILFVRKNAIVVLIPKYGLEGTVFFEEKD--------------KPNPQ 854
Query: 927 QRFQNKITSTTTDGESVTFHLFDHVTVRISIQASRCHSDTIRLEII 972
+ ++I S E FH+FD V V+I + +S IR+ ++
Sbjct: 855 LIYDDEIPSLKI--EDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLV 898
>gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2
[Homo sapiens]
Length = 885
Score = 284 bits (727), Expect = 3e-76
Identities = 225/746 (30%), Positives = 362/746 (48%), Gaps = 79/746 (10%)
Query: 214 ENESQESHGKEYPE-----HLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASS 268
+ E++ ++ + PE HLP + L++ S I +EA + G+ S
Sbjct: 130 DKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVI------------VEA--QFDGSDS 175
Query: 269 KDSD-LVSDILIHGMKARNRSIH------GDVVVVELLPKNEWKGRTVALCENDCDDKAS 321
+D + ++L+ G+K + + GD V K T + + D +A
Sbjct: 176 EDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVT--------KDETTCISQ---DTRAL 224
Query: 322 GESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRIST 381
E + + +VV IL+K F ++ + L +P D+R+P+I +
Sbjct: 225 SEKSLQR--SAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSPSDHRVPRIYVPL 282
Query: 382 QQAETLQDFRV----------VVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVEN 431
+ QDF + RI W+ + G + LG+ G++E E IL E
Sbjct: 283 KDCP--QDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEY 340
Query: 432 SISVIPFSEAQMCEMPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSV 491
+ FS + +P P W + PEE KR+DLRK +F+IDP D+DD LS
Sbjct: 341 GVDFSDFSSEVLECLPQGLP---WTIPPEEFSKRRDLRKD-CIFTIDPSTARDLDDALSC 396
Query: 492 RTLNNGNLELGVHIADVTHFVAPNSYIDIEARTRATTYYLADRRYDMLPSVLSADLCSLL 551
+ L +GN ++GVHIADV++FV S +D A RAT+ YL + MLP +L +LCSL
Sbjct: 397 KPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCEELCSLN 456
Query: 552 GGVDRYAVSIMWELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFK 611
D+ S++W L +I W+GRTIIRS KL YE AQ +++ S + IP K
Sbjct: 457 PMSDKLTFSVIWTLTPEG-KILDEWFGRTIIRSCTKLSYEHAQSMIE---SPTEKIPA-K 511
Query: 612 DLDEKSRQAKLEELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-HDLI 670
+L S + EE+ A+ L IA+ +R +R GAL L+ +++ LD + +
Sbjct: 512 ELPPISPEHSSEEVHQAVLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHETGLPQGCH 571
Query: 671 PKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFF 730
+ E ++ V E M+LAN VA KI +FP QALLR+HPPP S+L E G
Sbjct: 572 IYEYRESNKLVEEFMLLANMAVAHKIHRAFPEQALLRRHPPPQTRMLSDLVEFCDQMGLP 631
Query: 731 IDTRSNKTLADSLDN--ANDPHDPIVNRLLRSMATQAMSNALYFSTGSCAE-EEFHHYGL 787
+D S L SL +D + +L +M ++ M ALYF +G + +F HY L
Sbjct: 632 VDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSGLLQDPAQFRHYAL 691
Query: 788 ALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAA 847
+ YTHFTSPIRR++D++VHRLL AA+ +++++ + L++ H N+R A+
Sbjct: 692 NVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDM-----APDTLQKQADHCNDRRMAS 746
Query: 848 QHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY----- 902
+ Q+ ST LF + K+ P S+ ++ I + + R+G++ Y
Sbjct: 747 KRVQELSTSLFFAVLVKESGPLE-----SEAMVMGILKQAFDVLVLRYGVQKRIYCNALA 801
Query: 903 LKNKDGLVISCGPDSCSEWKPGSLQR 928
L++ + P+ W+P +++
Sbjct: 802 LRSHHFQKVGKKPELTLVWEPEDMEQ 827
Score = 63.2 bits (152), Expect = 1e-09
Identities = 41/116 (35%), Positives = 69/116 (59%), Gaps = 13/116 (11%)
Query: 212 ERENESQESHGKE---YPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLQGASS 268
+++++++ + GK+ + ++ E + G+K G IQG+L +N + EAF+ S
Sbjct: 34 DKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFH-EAFI-----PS 87
Query: 269 KDSDLVSDILIHGMKARNRSIHGDVVVVELLPKNEWKGRTVALCENDCDDKASGES 324
D D DI I G+ ARNR+++GD+VVV+LLP+ WK V ND + +A+ ES
Sbjct: 88 PDGD--RDIFIDGVVARNRALNGDLVVVKLLPEEHWK--VVKPESNDKETEAAYES 139
>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
[Homo sapiens]
Length = 2649
Score = 130 bits (326), Expect = 9e-30
Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%)
Query: 277 ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 326
I + G + GD V+V+LL P+ +GR + + + + A P
Sbjct: 1155 IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 1214
Query: 327 EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 385
+P G V I +D PS+ + S K R+ ++ + AE
Sbjct: 1215 IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 1258
Query: 386 TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 445
V+I W YP G VL E + + +E S+ V P +A + +
Sbjct: 1259 ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 1318
Query: 446 MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 505
+ +V+ E R + L F++DP+G ++DD LSVR L E+ VHI
Sbjct: 1319 VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 1372
Query: 506 ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 564
DV FV + +D+EAR + +Y R MLP+ L D+ SLL G DR A+S+
Sbjct: 1373 TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 1432
Query: 565 LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 624
++KAS ++K + + ++++S +L YE A+E++ + ++P +R ++
Sbjct: 1433 MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 1484
Query: 625 LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 679
V A + + R R + D C Q D+ + H ++ + ++ +
Sbjct: 1485 CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 1534
Query: 680 TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 714
VAE ++ V W+ P +AL +H PP
Sbjct: 1535 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1594
Query: 715 EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 774
L K F T+ + + D L +D H P + R + +A
Sbjct: 1595 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1647
Query: 775 GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 831
G CA +++ HY L +D YT TSPIRRY D+V+ R ++ A+ G+ +S +
Sbjct: 1648 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1701
Query: 832 DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 864
D++ LC+ + ++ AQ Q+++ L + K
Sbjct: 1702 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1734
>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
[Homo sapiens]
Length = 2080
Score = 130 bits (326), Expect = 9e-30
Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%)
Query: 277 ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 326
I + G + GD V+V+LL P+ +GR + + + + A P
Sbjct: 586 IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 645
Query: 327 EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 385
+P G V I +D PS+ + S K R+ ++ + AE
Sbjct: 646 IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 689
Query: 386 TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 445
V+I W YP G VL E + + +E S+ V P +A + +
Sbjct: 690 ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 749
Query: 446 MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 505
+ +V+ E R + L F++DP+G ++DD LSVR L E+ VHI
Sbjct: 750 VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 803
Query: 506 ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 564
DV FV + +D+EAR + +Y R MLP+ L D+ SLL G DR A+S+
Sbjct: 804 TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 863
Query: 565 LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 624
++KAS ++K + + ++++S +L YE A+E++ + ++P +R ++
Sbjct: 864 MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 915
Query: 625 LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 679
V A + + R R + D C Q D+ + H ++ + ++ +
Sbjct: 916 CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 965
Query: 680 TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 714
VAE ++ V W+ P +AL +H PP
Sbjct: 966 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1025
Query: 715 EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 774
L K F T+ + + D L +D H P + R + +A
Sbjct: 1026 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1078
Query: 775 GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 831
G CA +++ HY L +D YT TSPIRRY D+V+ R ++ A+ G+ +S +
Sbjct: 1079 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1132
Query: 832 DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 864
D++ LC+ + ++ AQ Q+++ L + K
Sbjct: 1133 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1165
>gi|224809295 xeroderma pigmentosum, complementation group C isoform
1 [Homo sapiens]
Length = 940
Score = 32.3 bits (72), Expect = 2.4
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 2/113 (1%)
Query: 189 LDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVLEAGIKSGRYIQGIL 248
L +F DLK AH L + E E + + E E L VL +S + + +L
Sbjct: 99 LRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLL 158
Query: 249 NVNKHRAQIEA--FVRLQGASSKDSDLVSDILIHGMKARNRSIHGDVVVVELL 299
V +IE + + S K L MK N+ +H D V LL
Sbjct: 159 PVKPVEIEIETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLL 211
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 32.0 bits (71), Expect = 3.2
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 17 RTLRIVREHYLRPCVPCHSPLCPQPAACSHDGKLLSSDVTHYVIPDWKVVQDYLEILEFP 76
+T +V H R PC PLC P SH G L +V + + WK + + ++
Sbjct: 391 QTAVVVMAHLDRLATPCMPPLCSSPT--SHKGSL--QEVIGWGLIGWKYYANVIGPIQCE 446
Query: 77 ELKGIIFMQTAC 88
L + Q AC
Sbjct: 447 GLANLGVTQIAC 458
>gi|239740946 PREDICTED: hypothetical protein XP_002344104 isoform 1
[Homo sapiens]
Length = 430
Score = 32.0 bits (71), Expect = 3.2
Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%)
Query: 788 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 842
ALD T T+ +RR +DI + + L +K + I+ L LE+ + N
Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334
Query: 843 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 902
SQ T + K A E S+G+ +++N + + RF G A
Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390
Query: 903 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 942
L+ CSE Q F + +T +++ GES
Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411
>gi|239740944 PREDICTED: hypothetical protein XP_002344105 isoform 2
[Homo sapiens]
Length = 430
Score = 32.0 bits (71), Expect = 3.2
Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%)
Query: 788 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 842
ALD T T+ +RR +DI + + L +K + I+ L LE+ + N
Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334
Query: 843 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 902
SQ T + K A E S+G+ +++N + + RF G A
Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390
Query: 903 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 942
L+ CSE Q F + +T +++ GES
Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411
>gi|239740942 PREDICTED: hypothetical protein XP_002344106 isoform 3
[Homo sapiens]
Length = 430
Score = 32.0 bits (71), Expect = 3.2
Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%)
Query: 788 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 842
ALD T T+ +RR +DI + + L +K + I+ L LE+ + N
Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334
Query: 843 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 902
SQ T + K A E S+G+ +++N + + RF G A
Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390
Query: 903 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 942
L+ CSE Q F + +T +++ GES
Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411
>gi|32698714 hypothetical protein LOC284058 [Homo sapiens]
Length = 1105
Score = 32.0 bits (71), Expect = 3.2
Identities = 39/160 (24%), Positives = 63/160 (39%), Gaps = 30/160 (18%)
Query: 788 ALDKYTHFTSPIRRYSDIV-----VHRLLMAAISKDKKMEIKGNLFSNKDLEELCRHINN 842
ALD T T+ +RR +DI + + L +K + I+ L LE+ + N
Sbjct: 277 ALDSDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQL--GGFLEKTLSKLPN 334
Query: 843 RNQAAQHSQKQSTELFQCMYFKDKDPATEERCISDGVIYSIRTNGVLLFIPRFGIKGAAY 902
SQ T + K A E S+G+ +++N + + RF G A
Sbjct: 335 LESLRPRSQLMLTRKAEAALRK----AASETTTSEGLSNFLKSNSISEELERFTASGIAN 390
Query: 903 LKNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGES 942
L+ CSE Q F + +T +++ GES
Sbjct: 391 LR-------------CSE------QAFDSDVTDSSSGGES 411
>gi|126032345 sterile alpha motif domain containing 3 isoform b
[Homo sapiens]
Length = 221
Score = 31.6 bits (70), Expect = 4.1
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 19/145 (13%)
Query: 122 QQCCYLPRER-GESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDE------EAIQQYG 174
Q C +L + GE + ++Q + AA+ + DRM +V + + I++Y
Sbjct: 8 QVCSWLVEKNLGELVHRFQEEEVSGAALLALN---DRMVQQLVKKIGHQAVLMDLIKKYK 64
Query: 175 SETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVL 234
T+G L + KAA + + R+ E+ S HG++ P P E L
Sbjct: 65 QNTQG---------LKSPENPKKAALVMQTEAARDYRDEESSSPARHGEQMPSFYPAENL 115
Query: 235 EAGIKSGRYIQGILNVNKHRAQIEA 259
+ G+ R ++ NV + A+ +A
Sbjct: 116 DNGLIDQRVLKQRRNVKQILARSKA 140
>gi|126032305 sterile alpha motif domain containing 3 isoform a
[Homo sapiens]
Length = 520
Score = 31.6 bits (70), Expect = 4.1
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 19/145 (13%)
Query: 122 QQCCYLPRER-GESMEKWQTRSIYNAAVWYYHHCQDRMPIVMVTEDE------EAIQQYG 174
Q C +L + GE + ++Q + AA+ + DRM +V + + I++Y
Sbjct: 8 QVCSWLVEKNLGELVHRFQEEEVSGAALLALN---DRMVQQLVKKIGHQAVLMDLIKKYK 64
Query: 175 SETEGVFVITFKNYLDNFWPDLKAAHELCDSILQSRRERENESQESHGKEYPEHLPLEVL 234
T+G L + KAA + + R+ E+ S HG++ P P E L
Sbjct: 65 QNTQG---------LKSPENPKKAALVMQTEAARDYRDEESSSPARHGEQMPSFYPAENL 115
Query: 235 EAGIKSGRYIQGILNVNKHRAQIEA 259
+ G+ R ++ NV + A+ +A
Sbjct: 116 DNGLIDQRVLKQRRNVKQILARSKA 140
>gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
Length = 334
Score = 31.2 bits (69), Expect = 5.4
Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Query: 810 LLMAAISKDKKMEIKGNLFSNKDLEELCRHINNRNQAAQHS-----QKQSTELF 858
L+M AI K K ++ K + + K+ E+ CR + QA S KQ +LF
Sbjct: 121 LIMDAIHKQKSLQFKKTMDAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLF 174
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/154 (20%), Positives = 66/154 (42%), Gaps = 20/154 (12%)
Query: 904 KNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHL-----------FDHVT 952
K L I+C E + L+R K+ T +++TF L +++
Sbjct: 646 KKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 953 VRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKS-ELVKEVTKSVEEAQLAQ 1011
+R ++++ +C S + ++ N EL + L K EL+K K E +++
Sbjct: 706 LRRNVESLKCAS-------MKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSY 758
Query: 1012 EVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLAL 1045
+ ++I + Q+ + + + L E++DL +
Sbjct: 759 Q-GLDIENQRLQKTLENSNKKIQQLESELQDLEM 791
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 30.8 bits (68), Expect = 7.0
Identities = 31/154 (20%), Positives = 66/154 (42%), Gaps = 20/154 (12%)
Query: 904 KNKDGLVISCGPDSCSEWKPGSLQRFQNKITSTTTDGESVTFHL-----------FDHVT 952
K L I+C E + L+R K+ T +++TF L +++
Sbjct: 646 KKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Query: 953 VRISIQASRCHSDTIRLEIISNKPYKIPNTELIHQSSPLLKS-ELVKEVTKSVEEAQLAQ 1011
+R ++++ +C S + ++ N EL + L K EL+K K E +++
Sbjct: 706 LRRNVESLKCAS-------MKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSY 758
Query: 1012 EVKVNIIQEEYQEYRQTKGRSLYTLLEEIRDLAL 1045
+ ++I + Q+ + + + L E++DL +
Sbjct: 759 Q-GLDIENQRLQKTLENSNKKIQQLESELQDLEM 791
>gi|170016081 XRP2 protein [Homo sapiens]
Length = 350
Score = 30.4 bits (67), Expect = 9.2
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 46 HDGKLLSSDVTHYVIPDWKVVQDYLEILEFPELKGI-IFMQTACQAVQHQRGRRQYNKLR 104
HD +S ++ ++P+ VVQDY+ I ELK + + + V RG+RQ +
Sbjct: 175 HDFTPVSGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDE 234
Query: 105 NLLKDARHDCILFANEF 121
+ L +LFA ++
Sbjct: 235 SCL------VVLFAGDY 245
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 30.4 bits (67), Expect = 9.2
Identities = 18/78 (23%), Positives = 36/78 (46%)
Query: 968 RLEIISNKPYKIPNTELIHQSSPLLKSELVKEVTKSVEEAQLAQEVKVNIIQEEYQEYRQ 1027
R + I + ++ + + + L + E + + EE +L QE K + QE+ Q
Sbjct: 571 RRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQ 630
Query: 1028 TKGRSLYTLLEEIRDLAL 1045
K +++ LE+I+ L
Sbjct: 631 IKKKTVRERLEQIKKTEL 648
>gi|189011592 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform b [Homo sapiens]
Length = 422
Score = 30.4 bits (67), Expect = 9.2
Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Query: 564 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 623
E +K+ YE+ V G ++R+ ++ E+ D +IP D SR +
Sbjct: 72 ETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIP---DKGRFSRTNIIS 128
Query: 624 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 683
+L I +LT I + RD A +L E+ ++ + K + ++ E HE AE
Sbjct: 129 DLEEQISELTAIIEQM--NRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE--AE 184
Query: 684 CMILANHWVAKKIWESFPHQALLRQ 708
L N++ A E Q L +
Sbjct: 185 LSELENNYKAALKAEKLAAQEKLEE 209
>gi|189011586 amyotrophic lateral sclerosis 2 (juvenile) chromosome
region, candidate 12 isoform a [Homo sapiens]
Length = 445
Score = 30.4 bits (67), Expect = 9.2
Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 7/145 (4%)
Query: 564 ELDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLE 623
E +K+ YE+ V G ++R+ ++ E+ D +IP D SR +
Sbjct: 72 ETNKSFYEVINVSPGYQLVRNREQISVTLGDEMFDRKKRWESEIP---DKGRFSRTNIIS 128
Query: 624 ELVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNIHDLIPKQPLEVHETVAE 683
+L I +LT I + RD A +L E+ ++ + K + ++ E HE AE
Sbjct: 129 DLEEQISELTAIIEQM--NRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHE--AE 184
Query: 684 CMILANHWVAKKIWESFPHQALLRQ 708
L N++ A E Q L +
Sbjct: 185 LSELENNYKAALKAEKLAAQEKLEE 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,009,110
Number of Sequences: 37866
Number of extensions: 1789060
Number of successful extensions: 5128
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 5068
Number of HSP's gapped (non-prelim): 36
length of query: 1054
length of database: 18,247,518
effective HSP length: 113
effective length of query: 941
effective length of database: 13,968,660
effective search space: 13144509060
effective search space used: 13144509060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.