Search of human proteins with 218156303

Search of human proteins with 218156303

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|218156303 anoctamin 6 isoform b [Homo sapiens]
         (892 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|218156303 anoctamin 6 isoform b [Homo sapiens]                    1837   0.0  
gi|218156299 anoctamin 6 isoform a [Homo sapiens]                    1826   0.0  
gi|218156307 anoctamin 6 isoform c [Homo sapiens]                    1695   0.0  
gi|218156305 anoctamin 6 isoform c [Homo sapiens]                    1695   0.0  
gi|218081589 anoctamin 5 isoform b [Homo sapiens]                     880   0.0  
gi|47106048 anoctamin 5 isoform a [Homo sapiens]                      880   0.0  
gi|218084958 anoctamin 4 [Homo sapiens]                               722   0.0  
gi|156766084 transmembrane protein 16C [Homo sapiens]                 695   0.0  
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho...   582   e-166
gi|209862785 anoctamin 2 [Homo sapiens]                               561   e-160
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s...   521   e-148
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]     424   e-118
gi|94536803 transmembrane protein 16K [Homo sapiens]                  172   1e-42
gi|55741655 anoctamin 8 [Homo sapiens]                                117   5e-26
gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]            69   1e-11
gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]            65   3e-10
gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]            64   5e-10
gi|12965174 taste receptor, type 2, member 8 [Homo sapiens]            33   0.90 
gi|28973795 taste receptor, type 2, member 60 [Homo sapiens]           33   1.2  
gi|52546687 olfactory receptor, family 1, subfamily L, member 4 ...    30   10.0 

>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
          Length = 892

 Score = 1837 bits (4759), Expect = 0.0
 Identities = 892/892 (100%), Positives = 892/892 (100%)

Query: 1   MFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDE 60
           MFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDE
Sbjct: 1   MFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDE 60

Query: 61  SRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAE 120
           SRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAE
Sbjct: 61  SRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAE 120

Query: 121 IMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVD 180
           IMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVD
Sbjct: 121 IMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVD 180

Query: 181 RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED 240
           RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED
Sbjct: 181 RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED 240

Query: 241 PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA 300
           PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA
Sbjct: 241 PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA 300

Query: 301 CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT 360
           CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT
Sbjct: 301 CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT 360

Query: 361 LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEE 420
           LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEE
Sbjct: 361 LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEE 420

Query: 421 ERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPI 480
           ERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPI
Sbjct: 421 ERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPI 480

Query: 481 QKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQ 540
           QKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQ
Sbjct: 481 QKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQ 540

Query: 541 FVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIW 600
           FVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIW
Sbjct: 541 FVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIW 600

Query: 601 NNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVT 660
           NNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVT
Sbjct: 601 NNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVT 660

Query: 661 LFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVT 720
           LFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVT
Sbjct: 661 LFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVT 720

Query: 721 NAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYS 780
           NAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYS
Sbjct: 721 NAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYS 780

Query: 781 DLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPD 840
           DLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPD
Sbjct: 781 DLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPD 840

Query: 841 VSKRTKSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE 892
           VSKRTKSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE
Sbjct: 841 VSKRTKSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE 892


>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
          Length = 910

 Score = 1826 bits (4731), Expect = 0.0
 Identities = 887/887 (100%), Positives = 887/887 (100%)

Query: 6   VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET 65
           VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET
Sbjct: 24  VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET 83

Query: 66  NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK 125
           NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK
Sbjct: 84  NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK 143

Query: 126 LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF 185
           LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF
Sbjct: 144 LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF 203

Query: 186 NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN 245
           NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN
Sbjct: 204 NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN 263

Query: 246 ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG 305
           ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG
Sbjct: 264 ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG 323

Query: 306 YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV 365
           YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV
Sbjct: 324 YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV 383

Query: 366 FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF 425
           FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF
Sbjct: 384 FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF 443

Query: 426 TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT 485
           TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT
Sbjct: 444 TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT 503

Query: 486 PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY 545
           PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY
Sbjct: 504 PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY 563

Query: 546 SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE 605
           SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE
Sbjct: 564 SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE 623

Query: 606 VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS 665
           VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS
Sbjct: 624 VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS 683

Query: 666 FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII 725
           FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII
Sbjct: 684 FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII 743

Query: 726 AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH 785
           AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH
Sbjct: 744 AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH 803

Query: 786 TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRT 845
           TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRT
Sbjct: 804 TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRT 863

Query: 846 KSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE 892
           KSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE
Sbjct: 864 KSKIQREKYLTQKLLHENHLKDMTKNMGVIAERMIEAVDNNLRPKSE 910


>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
          Length = 929

 Score = 1695 bits (4389), Expect = 0.0
 Identities = 819/821 (99%), Positives = 821/821 (100%)

Query: 6   VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET 65
           VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET
Sbjct: 24  VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET 83

Query: 66  NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK 125
           NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK
Sbjct: 84  NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK 143

Query: 126 LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF 185
           LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF
Sbjct: 144 LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF 203

Query: 186 NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN 245
           NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN
Sbjct: 204 NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN 263

Query: 246 ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG 305
           ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG
Sbjct: 264 ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG 323

Query: 306 YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV 365
           YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV
Sbjct: 324 YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV 383

Query: 366 FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF 425
           FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF
Sbjct: 384 FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF 443

Query: 426 TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT 485
           TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT
Sbjct: 444 TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT 503

Query: 486 PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY 545
           PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY
Sbjct: 504 PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY 563

Query: 546 SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE 605
           SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE
Sbjct: 564 SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE 623

Query: 606 VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS 665
           VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS
Sbjct: 624 VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS 683

Query: 666 FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII 725
           FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII
Sbjct: 684 FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII 743

Query: 726 AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH 785
           AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH
Sbjct: 744 AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH 803

Query: 786 TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHV 826
           TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVME++
Sbjct: 804 TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEYL 844


>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
          Length = 929

 Score = 1695 bits (4389), Expect = 0.0
 Identities = 819/821 (99%), Positives = 821/821 (100%)

Query: 6   VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET 65
           VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET
Sbjct: 24  VLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKET 83

Query: 66  NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK 125
           NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK
Sbjct: 84  NKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIK 143

Query: 126 LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF 185
           LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF
Sbjct: 144 LPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFF 203

Query: 186 NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN 245
           NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN
Sbjct: 204 NPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPN 263

Query: 246 ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG 305
           ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG
Sbjct: 264 ERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYG 323

Query: 306 YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV 365
           YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV
Sbjct: 324 YLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAV 383

Query: 366 FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF 425
           FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF
Sbjct: 384 FMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPF 443

Query: 426 TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT 485
           TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT
Sbjct: 444 TAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLT 503

Query: 486 PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY 545
           PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY
Sbjct: 504 PQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY 563

Query: 546 SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE 605
           SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE
Sbjct: 564 SSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQE 623

Query: 606 VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS 665
           VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS
Sbjct: 624 VLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVAS 683

Query: 666 FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII 725
           FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII
Sbjct: 684 FPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMII 743

Query: 726 AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH 785
           AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH
Sbjct: 744 AFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNH 803

Query: 786 TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHV 826
           TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVME++
Sbjct: 804 TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEYL 844


>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
          Length = 912

 Score =  880 bits (2275), Expect = 0.0
 Identities = 435/855 (50%), Positives = 597/855 (69%), Gaps = 37/855 (4%)

Query: 32  FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 91
           F++     DS+FF DG R+IDFVL Y D+ +K+   K        +R+ +E+NL   GL+
Sbjct: 60  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 113

Query: 92  LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 149
           LE    R   D +  FVK+HAPWEVL TYAE++ IK+P+K +D+         +++    
Sbjct: 114 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 171

Query: 150 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 209
           + +  S+  P  E+FTA F ++R   F I D+  FF  ++R+RIVY+ILSR  + + +  
Sbjct: 172 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 231

Query: 210 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 269
            +FGI RL+NS  Y +A+PLHD ++ + SE P+  NERY L++ WA     YK+QPLDLI
Sbjct: 232 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 291

Query: 270 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 329
           + YYGEKIGIYF +LG+YT+ML  AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM
Sbjct: 292 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 351

Query: 330 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 389
           CP CD++C +W+LN TC +SK   +FD+  T+ FA+FMG+WVTLFLEFWK+RQA LEYEW
Sbjct: 352 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 411

Query: 390 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 439
           D V+ ++E+Q    RPE+EA C H  +N +T+E E       RIP+          L  +
Sbjct: 412 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 463

Query: 440 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 499
            V  W+ L++ S++ +IVYRLSVF  F++ +  + +    ++ +LTPQ  TS+T S ++F
Sbjct: 464 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 522

Query: 500 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 559
           I+I+ILN  YEK++  IT  E+PRT  +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV
Sbjct: 523 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 582

Query: 560 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 619
           GYPG   Y   ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P  +N   R  
Sbjct: 583 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 642

Query: 620 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 679
             + SEK+  RWEQD+ L+  G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+
Sbjct: 643 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 702

Query: 680 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 739
           EIRVDAWKLTTQ+RR V  KA  IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+
Sbjct: 703 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 762

Query: 740 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 799
           ++S      + +  M GY+NN+LS+F +ADF N +  +   D     TCRYRD+RYPP  
Sbjct: 763 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 814

Query: 800 PQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKL 859
             +Y HN+ +WHV+AAK+ FIIVMEHV++ VKF +++ IPDV K    +I+REK +T K+
Sbjct: 815 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKI 874

Query: 860 LHENHLKDMTKNMGV 874
           LH+  L  + +N+G+
Sbjct: 875 LHDFELNKLKENLGI 889


>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
          Length = 913

 Score =  880 bits (2275), Expect = 0.0
 Identities = 435/855 (50%), Positives = 597/855 (69%), Gaps = 37/855 (4%)

Query: 32  FEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQ 91
           F++     DS+FF DG R+IDFVL Y D+ +K+   K        +R+ +E+NL   GL+
Sbjct: 61  FQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKA------ERRKEFETNLRKTGLE 114

Query: 92  LEAT--RSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKV 149
           LE    R   D +  FVK+HAPWEVL TYAE++ IK+P+K +D+         +++    
Sbjct: 115 LEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHT--PISYVLGP 172

Query: 150 LSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNV 209
           + +  S+  P  E+FTA F ++R   F I D+  FF  ++R+RIVY+ILSR  + + +  
Sbjct: 173 VRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGK 232

Query: 210 SKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLI 269
            +FGI RL+NS  Y +A+PLHD ++ + SE P+  NERY L++ WA     YK+QPLDLI
Sbjct: 233 KRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLI 292

Query: 270 RKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIM 329
           + YYGEKIGIYF +LG+YT+ML  AAVVG+ACF+YG L+ ++ T S E+C P+IGG++IM
Sbjct: 293 KNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIM 352

Query: 330 CPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEW 389
           CP CD++C +W+LN TC +SK   +FD+  T+ FA+FMG+WVTLFLEFWK+RQA LEYEW
Sbjct: 353 CPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEW 412

Query: 390 DTVELQQEEQA---RPEYEARCTHVVINEITQEEE-------RIPFTAWGKCIRITLCAS 439
           D V+ ++E+Q    RPE+EA C H  +N +T+E E       RIP+          L  +
Sbjct: 413 DLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPW--------YFLSGA 464

Query: 440 AVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISF 499
            V  W+ L++ S++ +IVYRLSVF  F++ +  + +    ++ +LTPQ  TS+T S ++F
Sbjct: 465 TVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDAS-LKQVKSFLTPQITTSLTGSCLNF 523

Query: 500 IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFV 559
           I+I+ILN  YEK++  IT  E+PRT  +YE+SLT+KMFLFQFVN+YSSCFY+AFFKGKFV
Sbjct: 524 IVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFV 583

Query: 560 GYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFH 619
           GYPG   Y   ++R+EECDPGGCL+ELTTQLTIIM GK I+ NI+E + P  +N   R  
Sbjct: 584 GYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRK 643

Query: 620 RVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNIL 679
             + SEK+  RWEQD+ L+  G LGLFYEYLE + QFGFVTLFVASFPLAPLLAL+NNI+
Sbjct: 644 ARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIV 703

Query: 680 EIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYW 739
           EIRVDAWKLTTQ+RR V  KA  IG WQ I+ G+A+L+V TNA I+AFTSD+IPRLVYY+
Sbjct: 704 EIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYY 763

Query: 740 SFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGH 799
           ++S      + +  M GY+NN+LS+F +ADF N +  +   D     TCRYRD+RYPP  
Sbjct: 764 AYST-----NATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDF---ITCRYRDYRYPPDD 815

Query: 800 PQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKL 859
             +Y HN+ +WHV+AAK+ FIIVMEHV++ VKF +++ IPDV K    +I+REK +T K+
Sbjct: 816 ENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKI 875

Query: 860 LHENHLKDMTKNMGV 874
           LH+  L  + +N+G+
Sbjct: 876 LHDFELNKLKENLGI 890


>gi|218084958 anoctamin 4 [Homo sapiens]
          Length = 920

 Score =  722 bits (1863), Expect = 0.0
 Identities = 393/864 (45%), Positives = 561/864 (64%), Gaps = 62/864 (7%)

Query: 38  KPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRS 97
           K + L+F DG+ RID++LVY   +            Q  KR+ +E N+   GLQ+E   S
Sbjct: 71  KSNGLYFRDGKCRIDYILVYRKSN-----------PQTEKREVFERNIRAEGLQMEKESS 119

Query: 98  VLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLK------PNDLKNRSSAFGTLNWFT---- 147
           +++  ++FVK+HAPWEVL  YAE M++++P +      P   K  S     ++ F     
Sbjct: 120 LINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLP 179

Query: 148 -KVLSVDESIIKP--EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQ 204
            K + +D+  +    E + +TAPF + R++ F I +++ FFN ATRSRIV+ IL R+KY+
Sbjct: 180 KKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYE 239

Query: 205 VINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSE--DPSCPNERYLLYREWAHPRSIYK 262
              N  K G+NRL+ +G Y+AAFPLH+  +R ++        N R+LLY  WA     YK
Sbjct: 240 EGKN--KIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYK 297

Query: 263 KQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPD 322
            QPLDL+R+Y+GEKIG+YFAWLG+YT ML  AA +G+  FLYG    D+   SKEVC   
Sbjct: 298 YQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT 357

Query: 323 IGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQ 382
               IIMCP CD+ CPF +L+ +C  +K   +FD+  T+ FAVFM VW T+FLEFWKRR+
Sbjct: 358 ---DIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRR 414

Query: 383 AELEYEWDTVELQQEEQA-RPEYEARCTHVV-INEITQEEERIPFTAW-GKCIRITLCAS 439
           A + Y+WD ++ ++EE+  RP++EA+ +    +N I+ + E  P+ A+  KC R+ + AS
Sbjct: 415 AVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPE--PYQAFTDKCSRLIVSAS 472

Query: 440 AVFFWILLIIASVIGIIVYRL---SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASI 496
            +FF I ++IA+V GI++YR+   S F  F   L +N             Q AT+ TA  
Sbjct: 473 GIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRN-----------NSQVATTGTAVC 521

Query: 497 ISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKG 556
           I+F IIM+LN +YEKVA+++TN E PRT++++ENS T+KMFLFQFVN  SS FYIAFF G
Sbjct: 522 INFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLG 581

Query: 557 KFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIG 616
           +F G+PG  +  + ++R EEC P GCL++L  Q+ IIM  K  WNN  E+  P I N   
Sbjct: 582 RFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWT 641

Query: 617 R--FHRVSGSE-KIT-PRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLL 672
           R    +  G E KI+ P+WE+DY+LQPM   GLF EYLEMI+QFGF T+FVA+FPLAPLL
Sbjct: 642 RRKVRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLL 701

Query: 673 ALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMI 732
           AL+NNI+EIR+DA+K  TQ+RR +  +A+DIG W  I++GI IL+V+TNA +IA TSD I
Sbjct: 702 ALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFI 761

Query: 733 PRLVYYWSFS-VPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT----- 786
           PRLVY + +      G+     M GY+N +LS+F+++DF+N+S+  P SD    +     
Sbjct: 762 PRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSE--PESDGSEFSGTPLK 819

Query: 787 TCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTK 846
            CRYRD+R PP     Y + + +WHV+AA+LAFIIV EH+++ +K  ISY IPD+ K  +
Sbjct: 820 YCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLR 879

Query: 847 SKIQREKYLTQKLLHENHLKDMTK 870
            +++REKYL Q++++E  L+ + K
Sbjct: 880 DRMRREKYLIQEMMYEAELERLQK 903


>gi|156766084 transmembrane protein 16C [Homo sapiens]
          Length = 981

 Score =  695 bits (1794), Expect = 0.0
 Identities = 377/855 (44%), Positives = 536/855 (62%), Gaps = 63/855 (7%)

Query: 44  FNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKL 103
           F DG++RID++LVY     ++TN       Q  KR  +E NL   GL LE   ++    +
Sbjct: 157 FKDGKKRIDYILVY-----RKTNI------QYDKRNTFEKNLRAEGLMLEKEPAIASPDI 205

Query: 104 VFVKVHAPWEVLCTYAEIMHIKLPLKPNDL--KNRSSAFGTL--------NWFTKVLSVD 153
           +F+K+H PW+ LC YAE ++I++P +        RS + G +        NW  +   V 
Sbjct: 206 MFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVL 265

Query: 154 ESIIKP---EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVS 210
           +    P   E + +T PF + R++ F I ++D FF+ ATRSRIVY +L R KY+  N +S
Sbjct: 266 DKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYE--NGIS 323

Query: 211 KFGINRLVNSGIYKAAFPLHDCKFRRQS--EDPSCPNERYLLYREWAHPRSIYKKQPLDL 268
           K GI +L+N+G Y AAFP H+  ++     +     N R+LLY  WA     YK QPLDL
Sbjct: 324 KVGIRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDL 383

Query: 269 IRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKII 328
           IR Y+GEKIG+YFAWLG+YT ML+ AA+VG+  F YG    +N   S+E+C      ++ 
Sbjct: 384 IRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKAT---EVF 440

Query: 329 MCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYE 388
           MCP CD+ C   +LN +C  +K   +FD+ GT+ FA+FM +W T+FLEFWKRR++ L Y 
Sbjct: 441 MCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYT 500

Query: 389 WDTVELQQEEQA-RPEYEARCTHV-VINEITQEEERIPFTAWGKCIRITLCASAVFFWIL 446
           WD +E ++EE+  RP++EA+   + ++N IT + E    ++  K  R+ +  S +FF I 
Sbjct: 501 WDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSS-DKVTRLLVSVSGIFFMIS 559

Query: 447 LIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILN 506
           L+I +V G++VYRL V   F A    N      I++Y   Q ATS  A  I+FIIIM+LN
Sbjct: 560 LVITAVFGVVVYRLVVMEQF-ASFKWNF-----IKQYW--QFATSAAAVCINFIIIMLLN 611

Query: 507 TIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPV 566
             YEK+A ++TN E PRT++++ENS  +KMFLFQFVN  SS FYIAFF G+FVG+PG   
Sbjct: 612 LAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYN 671

Query: 567 YWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGS-- 624
               ++R EEC P GCL++L  Q+ +IM  K IWNN  E+  P I N   R H++     
Sbjct: 672 KLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSR-HKIKRGIH 730

Query: 625 EKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVD 684
           +   P+WE D++LQPM   GL  EYLEM++QFGF T+FVA+FPLAPLLAL+NNI+EIR+D
Sbjct: 731 DASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLD 790

Query: 685 AWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVP 744
           A+K  TQ+RR +P +A DIG W  I++GI ILAV+TNA +IA TSD IPR VY + +   
Sbjct: 791 AYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYG-- 848

Query: 745 PYGDH---TSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQ 801
           P  +H   +   ++GY+NN+LS F +++            +G    CRYRD+R PP   +
Sbjct: 849 PCANHVEPSENCLKGYVNNSLSFFDLSEL----------GMGKSGYCRYRDYRGPPWSSK 898

Query: 802 EYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLH 861
            Y+  + YWH++AA+LAFIIV EH+++ +K FI+Y IPDV K    +I+REKYL Q++++
Sbjct: 899 PYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMY 958

Query: 862 E---NHLKDMTKNMG 873
           E    HL+   +  G
Sbjct: 959 EAELEHLQQQRRKSG 973


>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
           sapiens]
          Length = 986

 Score =  582 bits (1500), Expect = e-166
 Identities = 346/914 (37%), Positives = 512/914 (56%), Gaps = 129/914 (14%)

Query: 42  LFFNDGQRRIDFVLVYEDESRKETNK--------------------------KGTN---- 71
           L+F DG+R++D++LVY  + R   N+                          KG +    
Sbjct: 53  LYFRDGRRKVDYILVYHHK-RPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAG 111

Query: 72  ----------EKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEI 121
                     + +R +R+ YE NL+  GL+LE         + FVK+HAPW VLC  AE 
Sbjct: 112 SGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEF 171

Query: 122 MHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPE--------QEFFTAPFEKNRM 173
           + +K+P K   + + +   G L     VL      I+P+         +  + PF + + 
Sbjct: 172 LKLKMPTKK--MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQ 229

Query: 174 NDFYIVDRDAFFNPATRSRIVYFILSRV-----KYQVINNVSKFGINRLVNSGIYKAAFP 228
           + F + D+D+FF+  TRS IVY IL R      KY +       GI  L+ +G+Y AA+P
Sbjct: 230 HLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-------GITSLLANGVYAAAYP 282

Query: 229 LHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYT 288
           LHD  +  ++ +    N+R LLY EWA     YK QP+DL+RKY+GEKIG+YFAWLG YT
Sbjct: 283 LHDGDYNGENVEF---NDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYT 339

Query: 289 QMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCES 348
           QML+ A++VG+  FLYG    D    S E+C  D    I MCP CD+ C +WK++  C +
Sbjct: 340 QMLIPASIVGIIVFLYGCATMDENIPSMEMC--DQRHNITMCPLCDKTCSYWKMSSACAT 397

Query: 349 SKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-----RPE 403
           ++   +FD+  T+ F+VFM +W   F+E WKR+Q  L Y WD    ++EE+A     R E
Sbjct: 398 ARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAE 457

Query: 404 YEARCTHVVINEITQEEER---IP---FTAWGKCIRITLCA------------------- 438
           YEAR     + + ++ +E+   IP      W + ++  +                     
Sbjct: 458 YEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYL 517

Query: 439 ---SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITAS 495
               ++ F I +  A V+G+I+YR+S+    +      +N +  ++  +  +   + TA 
Sbjct: 518 TNLVSIIFMIAVTFAIVLGVIIYRISMAAALA------MNSSPSVRSNI--RVTVTATAV 569

Query: 496 IISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFK 555
           II+ ++I++L+ +Y  +A  +T  E+P+T+  +E  L  K FL +FVN Y+  FY+AFFK
Sbjct: 570 IINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFK 629

Query: 556 GKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGK-AIWNNIQEVLLPWIMNL 614
           G+FVG PGD VY    +R EEC PGGCL+EL  QL+IIM GK  I NN+ E+ +P +  L
Sbjct: 630 GRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKL 689

Query: 615 IGRFHRVSGSE--------KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASF 666
           I R+ ++            K   R+E DY+L+P    GL  EY+EMIIQFGFVTLFVASF
Sbjct: 690 I-RYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASF 746

Query: 667 PLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIA 726
           PLAPL AL+NNI+EIR+DA K  T+ RR V  +A+DIG W  I++GI  LAV+ NA +I+
Sbjct: 747 PLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVIS 806

Query: 727 FTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT 786
           FTSD IPRLVY + +S        + TM G++N+TLS F V+DF+N +  N   DLG   
Sbjct: 807 FTSDFIPRLVYLYMYS-------KNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEV 859

Query: 787 -TCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRT 845
             CRY+D+R PP    +Y  +  +W V+AA+LAF+IV ++++  +  F+ + IPD+ K  
Sbjct: 860 QICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDI 919

Query: 846 KSKIQREKYLTQKL 859
             +I +EK L  +L
Sbjct: 920 SQQIHKEKVLMVEL 933


>gi|209862785 anoctamin 2 [Homo sapiens]
          Length = 998

 Score =  561 bits (1447), Expect = e-160
 Identities = 331/895 (36%), Positives = 488/895 (54%), Gaps = 98/895 (10%)

Query: 42  LFFNDGQRRIDFVLVYEDESRK------------------ETNKK--------------- 68
           + F+D QR++D+VL Y    R                   ET K+               
Sbjct: 86  MHFHDSQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLD 145

Query: 69  GTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPL 128
              E+++ +R+ +E NL+  GL+LE          +FV++HAPW+VL   AE + IK+P 
Sbjct: 146 ALEEERKEQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPT 205

Query: 129 KPNDLKNRSSAFGTLNWFTKVLSVDESIIKP--------EQEFFTAPFEKNRMNDFYIVD 180
           K   +    +       F+  L    S ++P        + +  + PF + +M  + I +
Sbjct: 206 KK--MYEIKAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLYNIQE 263

Query: 181 RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSED 240
           +D FF+ ATRSRIV+ IL R      NN    GIN L+ + IY+AA+PLHD ++    +D
Sbjct: 264 KDTFFDNATRSRIVHEILKRTACSRANNT--MGINSLIANNIYEAAYPLHDGEYDSPEDD 321

Query: 241 PSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVA 300
               N+R LLY+EWA     YK QP+DLIRKY+GEKIG+YFAWLG YT  L+ ++V+GV 
Sbjct: 322 M---NDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVI 378

Query: 301 CFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGT 360
            FLYG    +    S+E+C  D      MCP CD+ C +W L+  C +++   +FD+  T
Sbjct: 379 VFLYGCATIEEDIPSREMC--DQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPAT 436

Query: 361 LVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQ-----ARPEYEARCTHVVINE 415
           + F++FM +W T+FLE WKR Q  L Y WD   +++EE+     +RPEYE +    ++ E
Sbjct: 437 VFFSIFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKE 496

Query: 416 ITQ---------------EEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRL 460
             Q               E++    T   +     +  +++ F I L  + V G+IVYR+
Sbjct: 497 SNQSAVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRI 556

Query: 461 SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFE 520
           +     S       N           +   + TA II+ ++I+IL+ IY  VA  +T  E
Sbjct: 557 TTAAALSLNKATRSN----------VRVTVTATAVIINLVVILILDEIYGAVAKWLTKIE 606

Query: 521 LPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPG 580
           +P+T+  +E  L +K FL +FVN YS  FY+AFFKG+FVG PG  VY    YR EEC PG
Sbjct: 607 VPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPG 666

Query: 581 GCLLELTTQLTIIMGGKA-IWNNIQEVLLPWIMNLIGRF-------HRVSGSEKITPRWE 632
           GCL+EL  QL+IIM GK  I NNI E+ +P +  L  +           S   K   +W+
Sbjct: 667 GCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWD 726

Query: 633 QDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQF 692
            DY L+P    GL  EY+EMIIQFGFVTLFVASFPLAP+ AL+NN++E+R+DA K  T+ 
Sbjct: 727 LDYSLEPY--TGLTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTEL 784

Query: 693 RRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY 752
           RR    + +DIG W  I+ GI   +V++NA +IA TSD IPRLVY +S+S      H   
Sbjct: 785 RRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYS------HNG- 837

Query: 753 TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHV 812
           T+ G++N+TLS F V+  K  ++            CR++D+R PP  P  Y+ +  YW +
Sbjct: 838 TLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFI 897

Query: 813 IAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREK-YLTQKLLHENHLK 866
           ++A+LAF+I+ ++++  +   + + IPD+      +I++EK  L    L E H K
Sbjct: 898 LSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEK 952


>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
           sapiens]
          Length = 933

 Score =  521 bits (1343), Expect = e-148
 Identities = 318/839 (37%), Positives = 477/839 (56%), Gaps = 69/839 (8%)

Query: 49  RRIDFVLVYEDESR----KETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLV 104
           R  DFVLV+E++ +    +++  +   +  R  R+ +  NL   GL ++  + V D    
Sbjct: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ-QDVQDGNTT 166

Query: 105 --FVKVHAPWEVLCTYAEIMHIKLPLK--PNDLKNRSSAFGTLNWFTKVLSVDESIIKPE 160
             +  + A W VLC YAE + +KLPL+  PN   N S+  G L W      + E +    
Sbjct: 167 VHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSA--GLLAWLGIPNVLLEVVPDVP 224

Query: 161 QEFFTAPFEKNRMNDFYIVD-RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVN 219
            E+++  F  N++  F   D +D FF    R +I++ IL++  Y      +  GI++L+ 
Sbjct: 225 PEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGH-EKKNLLGIHQLLA 283

Query: 220 SGIYKAAFPLHDCKFRRQSEDPSCP--NERYLLYREWAHPRSIYKKQPLDLIRKYYGEKI 277
            G+  AAFPLHD  F+   E P  P  N+R +L++ WA      K QPLD +R+Y+GEK+
Sbjct: 284 EGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKV 343

Query: 278 GIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGK--IIMCPQCDR 335
            +YFAWLG+YT  LL AAVVG   FL G     +   ++E+C    G K    MCP C  
Sbjct: 344 ALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELC----GSKDSFEMCPLCLD 399

Query: 336 LCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ 395
            CPFW L+  C  ++   +FD  GT+ F++FM +W  L LE+WKR+ A L Y WD  + +
Sbjct: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458

Query: 396 Q-EEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIG 454
             EE+ RP++ A       N IT E+E   F    +  R+   +  +   + +++  ++ 
Sbjct: 459 DTEERPRPQFAASAPMTAPNPITGEDEPY-FPERSRARRMLAGSVVIVVMVAVVVMCLVS 517

Query: 455 IIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAI 514
           II+YR  + IV S       +G   +  + +     S+T S+++ + I+IL+ IY  +A 
Sbjct: 518 IILYRAIMAIVVSR------SGNTLLAAWAS--RIASLTGSVVNLVFILILSKIYVSLAH 569

Query: 515 MITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRN 574
           ++T +E+ RTQT +E++ T+K+F+FQFVN+YSS  YIAFFKG+FVGYPG+  + L   RN
Sbjct: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGN-YHTLFGVRN 628

Query: 575 EECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPR---- 630
           EEC  GGCL+EL  +L +IM GK + NN+QEVL+P +     +F   S   K        
Sbjct: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688

Query: 631 ---WEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWK 687
              WE DY L P    GLF EYLEM++QFGFVT+FVA+ PLAPL AL+NN +EIR+DA K
Sbjct: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746

Query: 688 LTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYG 747
              ++RR V E+AQDIG W  I+ G+  LAV++NA ++AF+SD +PR  Y W+       
Sbjct: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWT------- 799

Query: 748 DHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-TCRYRDFRYPPGHPQEYKHN 806
              ++ + G++N TL+              P S    H  TCRYR FR   GH     ++
Sbjct: 800 --RAHDLRGFLNFTLA------------RAPSSFAAAHNRTCRYRAFRDDDGH-----YS 840

Query: 807 IYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLHENHL 865
             YW+++A +LAF+IV EHV++SV   +   +PD+ +  + K++RE YL ++ L EN +
Sbjct: 841 QTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEV 899


>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
          Length = 782

 Score =  424 bits (1091), Expect = e-118
 Identities = 242/672 (36%), Positives = 383/672 (56%), Gaps = 56/672 (8%)

Query: 201 VKYQVINNVSKFG--INRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPR 258
           V + V+NN +  G     L+  G+++A FPLH  + R              L + WA  R
Sbjct: 123 VNFVVMNNKTSAGETFEDLMKDGVFEARFPLHKGEGR--------------LKKTWARWR 168

Query: 259 SIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEV 318
            ++++QP+D IR Y+GEK+ +YF WLG+YT ML+ AA+ G+  FL G+   +    SKE+
Sbjct: 169 HMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEI 228

Query: 319 CHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFW 378
           C       I+MCP  D    + +L+ TC  +K   +FD+ GT+VFA+FM +W T+FLE W
Sbjct: 229 CEAH---DILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIW 285

Query: 379 KRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCA 438
           KR++A +   WD     +E++        C    +                  +R T+  
Sbjct: 286 KRQRARVVLHWDLYVWDEEQEEMALQLINCPDYKLRPYQHSY-----------LRSTVIL 334

Query: 439 SAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIIS 498
                 I L+I     ++VYR+    +FS+      +    +++ +T  TA  +T +++ 
Sbjct: 335 VLTLLMICLMIGMAHVLVVYRVLASALFSS------SAVPFLEEQVT--TAVVVTGALVH 386

Query: 499 FIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKF 558
           ++ I+I+  I   VA+ + +FE+PRT ++ E+  T++ F  QF  ++SS  YIAF  G+ 
Sbjct: 387 YVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRI 446

Query: 559 VGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRF 618
            G+PG      G ++ EEC   GC+++L  Q+ IIMG K   +N  E L+PW+ +   R 
Sbjct: 447 NGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKC-RS 505

Query: 619 HRVSGSEKITPR------WEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLL 672
            R S S  + PR      W ++Y L P+    LF E++EM+IQ+GF T+FVA+FPLAPLL
Sbjct: 506 LRASESGHL-PRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLL 564

Query: 673 ALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMI 732
           AL +N++EIR+DA K+    RRLVP KA+DIG W  +++ I +LAV+ N M+IAFTS+ I
Sbjct: 565 ALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFI 624

Query: 733 PRLVYYWSFS-VPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYR 791
           PR+VY + +S     G+ T   ++GY+N++LS+F   DF++   G   S+  N T CRYR
Sbjct: 625 PRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPD-GIEGSE--NVTLCRYR 681

Query: 792 DFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQR 851
           D+R PP    +Y  +  +W ++A +LAF+I+ EHV   +K   ++ +PD+ +  K+K+  
Sbjct: 682 DYRNPP----DYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLE 737

Query: 852 EKY--LTQKLLH 861
            KY  L +K+ H
Sbjct: 738 VKYQRLREKMWH 749


>gi|94536803 transmembrane protein 16K [Homo sapiens]
          Length = 660

 Score =  172 bits (437), Expect = 1e-42
 Identities = 145/525 (27%), Positives = 239/525 (45%), Gaps = 115/525 (21%)

Query: 214 INRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYY 273
           + RL+ SGI    FPLHD +  ++ ED             W + R   K QP+D IR Y+
Sbjct: 158 LRRLLTSGIVIQVFPLHDSEALKKLEDT------------W-YTRFALKYQPIDSIRGYF 204

Query: 274 GEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQC 333
           GE I +YF +L Y+T  L+  AV+G+  +L+ + + D                       
Sbjct: 205 GETIALYFGFLEYFTFALIPMAVIGLPYYLFVWEDYDKY--------------------- 243

Query: 334 DRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVE 393
                                      ++FA F  +W T+ LE WKR  A + Y W T+ 
Sbjct: 244 ---------------------------VIFASFNLIWSTVILELWKRGCANMTYRWGTLL 276

Query: 394 LQQE-EQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASV 452
           ++++ E+ RP +      + IN IT +EE + + ++ + +RI L  S  F  + L  +  
Sbjct: 277 MKRKFEEPRPGFHGV---LGINSITGKEEPL-YPSYKRQLRIYL-VSLPFVCLCLYFSLY 331

Query: 453 IGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKV 512
           + +I + + V+ +    L +N +G++     L          SII  I+I I+N +Y   
Sbjct: 332 VMMIYFDMEVWAL---GLHEN-SGSEWTSVLL-------YVPSIIYAIVIEIMNRLYRYA 380

Query: 513 AIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY 572
           A  +T++E  R ++ Y+N L +K+ +F F+N ++S FYIAF                   
Sbjct: 381 AEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAFVLKD--------------- 425

Query: 573 RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKI----- 627
                     +  L   L  ++    I N I E  LP+ +    R H V    K+     
Sbjct: 426 ----------MKLLRQSLATLLITSQILNQIMESFLPYWLQ---RKHGVRVKRKVQALKA 472

Query: 628 ---TPRWEQDYHLQPMGK-LGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRV 683
                 +EQ    + MG  LG F +YLE+ +QFG+V+LF   +PLA   A++NN  E+  
Sbjct: 473 DIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNS 532

Query: 684 DAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFT 728
           DA K+   F+R   E + +IG WQ   + +++++VVTN  +I  +
Sbjct: 533 DALKMCRVFKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMS 577



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 14/56 (25%), Positives = 36/56 (64%)

Query: 817 LAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLHENHLKDMTKNM 872
           +  ++ +EH + ++KF +++AIPD  +  + K+ R ++ + + L +  +K +T+N+
Sbjct: 592 ILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENL 647


>gi|55741655 anoctamin 8 [Homo sapiens]
          Length = 1232

 Score =  117 bits (293), Expect = 5e-26
 Identities = 99/380 (26%), Positives = 170/380 (44%), Gaps = 88/380 (23%)

Query: 184 FFNPATRSRIVYFILSRVKY---QVINNVSKFG----INRLVNSGIYKAAFPLHDCKFRR 236
           FF    R  I+ F L  ++    + ++NV        I  L   GI +  FP+H+ +   
Sbjct: 159 FFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHEQRILN 218

Query: 237 QSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAV 296
           +            L + W   +++ + QPLD I  Y+G KI +YFAWLG+YT  ++  AV
Sbjct: 219 R------------LMKSWV--QAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAV 264

Query: 297 VGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFD 356
            G   + +   +Q +                               +++C          
Sbjct: 265 FGSVLYTFTEADQTS------------------------------RDVSC---------- 284

Query: 357 SFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQE--EQARPEYEARCTHVVIN 414
               +VFA+F  +W TLFLE WKRR AEL Y+W T++   E  E+ RP++        I+
Sbjct: 285 ----VVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRR---IS 337

Query: 415 EITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNI 474
            IT+ EE   +  W + +   L +      + L +A ++ + +  L  F +   +L  ++
Sbjct: 338 PITRAEE-FYYPPWKRLLFQLLVS------LPLCLACLVCVFLLMLGCFQL--QELVLSV 388

Query: 475 NGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTM 534
            G   + ++L           ++  +++ +    Y+K+AI + + E  R ++ YE  L +
Sbjct: 389 KGLPRLARFL---------PKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLII 439

Query: 535 KMFLFQFVNYYSSCFYIAFF 554
           K+ LFQFVN Y S FYI F+
Sbjct: 440 KVVLFQFVNSYLSLFYIGFY 459



 Score = 87.0 bits (214), Expect = 7e-17
 Identities = 39/80 (48%), Positives = 57/80 (71%)

Query: 646 FYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGA 705
           F +Y EM +QFG+V LF ++FPLA L ALVNN++EIR DA+KL T  +R   ++ + IG 
Sbjct: 745 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQ 804

Query: 706 WQPIMQGIAILAVVTNAMII 725
           WQ +M+ + +LA+V N  +I
Sbjct: 805 WQKVMEAMGVLAIVVNCYLI 824


>gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 719

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 96/404 (23%), Positives = 158/404 (39%), Gaps = 98/404 (24%)

Query: 333 CDRLCPFW-------KLNITCESSKKL-CIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAE 384
           C  L P+W       K     +   KL C+FD  GT+ F++FM  W        +   A 
Sbjct: 229 CQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSAT 288

Query: 385 LEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTA---WG--------KCIR 433
           L + WD  + Q +++A P   +   H       Q++E +P +A   W         +C  
Sbjct: 289 LAHHWDCSDFQ-DQEAMP---SSAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPH 344

Query: 434 ITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTAT-SI 492
           +   A A+                 +++   V   K P        +   LT   A  ++
Sbjct: 345 LQFAALAL-----------------QMTQNPVTGLKEPY-FQPHSCLSHLLTSSAAILTV 386

Query: 493 TASIISFIIIMILNTIYEKVAIMITNFELPRTQTDY----ENSLTMKMFLFQFVNYYSSC 548
              ++ F++ +I+      +A+  T   +  TQ +         +MKM    F    S C
Sbjct: 387 LCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASMKMPSLSF----SVC 442

Query: 549 FYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLL 608
            ++ F               L      +C PGGC +++T QL IIM GK + N+++E   
Sbjct: 443 QFLFFSL-------------LHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEE--- 486

Query: 609 PWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPL 668
              + L G      G    TP   +                    +QFGF+T+FV +F L
Sbjct: 487 --FVGLGG------GPGPDTPCLPE--------------------LQFGFITIFVGAFLL 518

Query: 669 APLLALVNNILEIRVDAWKLTTQFRRLVPEK----AQDIGAWQP 708
           APL  L+NN +EI +DA K   +++R +  +      D   W+P
Sbjct: 519 APLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRP 562


>gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 494

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 35/138 (25%)

Query: 575 EECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQD 634
           ++C PGGC +++T QL IIM GK + N+++E      + L G      G    TP   + 
Sbjct: 231 QQCGPGGCHIQVTQQLIIIMVGKQLLNHMEE-----FVGLGG------GPGPDTPCLPE- 278

Query: 635 YHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRR 694
                              +QFGF+T+FV +F LAPL  L+NN +EI +DA K   +++R
Sbjct: 279 -------------------LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQR 319

Query: 695 LVPEK----AQDIGAWQP 708
            +  +      D   W+P
Sbjct: 320 PMAGRGWTSGSDCSCWRP 337



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 8/74 (10%)

Query: 333 CDRLCPFW-------KLNITCESSKKL-CIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAE 384
           C  L P+W       K     +   KL C+FD  GT+ F++FM  W        +   A 
Sbjct: 25  CQLLYPYWACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSAT 84

Query: 385 LEYEWDTVELQQEE 398
           L + WD  + Q +E
Sbjct: 85  LAHHWDCSDFQDQE 98


>gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 723

 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 44/137 (32%), Positives = 67/137 (48%), Gaps = 35/137 (25%)

Query: 576 ECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDY 635
           +C PGGC +++T QL IIM GK + N+++E      + L G      G    TP   +  
Sbjct: 461 QCGPGGCHIQVTQQLIIIMVGKQLLNHMEE-----FVGLGG------GPGPDTPCLPE-- 507

Query: 636 HLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRL 695
                             +QFGF+T+FV +F LAPL  L+NN +EI +DA K   +++R 
Sbjct: 508 ------------------LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRP 549

Query: 696 VPEK----AQDIGAWQP 708
           +  +      D   W+P
Sbjct: 550 MAGRGWTSGSDCSCWRP 566


>gi|12965174 taste receptor, type 2, member 8 [Homo sapiens]
          Length = 309

 Score = 33.5 bits (75), Expect = 0.90
 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 15/128 (11%)

Query: 441 VFFWILL------IIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK--YLTPQTATSI 492
           V  WILL      ++ S+I  IV          AK  +NI     + K  Y  P T  ++
Sbjct: 129 VVHWILLGCFAISLLVSLIAAIVLSCDYRFHAIAKHKRNITEMFHVSKIPYFEPLTLFNL 188

Query: 493 TA------SIISF-IIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYY 545
            A      S+ISF +++  L    +++ +  T    P T+       TM  F+F F  YY
Sbjct: 189 FAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMTSFIFFFFLYY 248

Query: 546 SSCFYIAF 553
            S   + F
Sbjct: 249 ISSILMTF 256


>gi|28973795 taste receptor, type 2, member 60 [Homo sapiens]
          Length = 318

 Score = 33.1 bits (74), Expect = 1.2
 Identities = 35/150 (23%), Positives = 61/150 (40%), Gaps = 29/150 (19%)

Query: 431 CIRITLCASAVFFWIL--------LIIASVIGIIVYRLSVFIVFSAKL----------PK 472
           C++I      VFFW+          ++ S +G+  +   +F + + ++          P 
Sbjct: 119 CVKIATFTHPVFFWLKHKLSGWLPWMLFSSVGLSSFTTILFFIGNHRMYQNYLRNHLQPW 178

Query: 473 NINGTDPIQK-----YLTPQTATSITASIISFIIIMILNTI----YEKVAIMITN-FELP 522
           N+ G D I+      YL P    + T     F I MIL       + K A++ T+ F  P
Sbjct: 179 NVTG-DSIRSYCEKFYLFPLKMITWTMPTAVFFICMILLITSLGRHRKKALLTTSGFREP 237

Query: 523 RTQTDYENSLTMKMFLFQFVNYYSSCFYIA 552
             Q   +  L +  F   F++Y+ S  + A
Sbjct: 238 SVQAHIKALLALLSFAMLFISYFLSLVFSA 267


>gi|52546687 olfactory receptor, family 1, subfamily L, member 4
           [Homo sapiens]
          Length = 311

 Score = 30.0 bits (66), Expect = 10.0
 Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 477 TDPIQKYLTPQTATS---ITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLT 533
           T P+ K     T++S   +    ++ I+   L TI+  + I++T   +P     ++   T
Sbjct: 182 TQPVLKLSCSDTSSSQMVVMTETLAVIVTPFLCTIFSYLQIIVTVLRIPSAAGKWKAFST 241

Query: 534 MKMFLFQFVNYYSSCFYIAF 553
               L   V +Y S  Y+ F
Sbjct: 242 CGSHLTVVVLFYGSVIYVYF 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.140    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,223,014
Number of Sequences: 37866
Number of extensions: 1450931
Number of successful extensions: 4368
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 4236
Number of HSP's gapped (non-prelim): 41
length of query: 892
length of database: 18,247,518
effective HSP length: 111
effective length of query: 781
effective length of database: 14,044,392
effective search space: 10968670152
effective search space used: 10968670152
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.