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Search of human proteins with 218084958
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218084958 anoctamin 4 [Homo sapiens]
(920 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218084958 anoctamin 4 [Homo sapiens] 1902 0.0
gi|156766084 transmembrane protein 16C [Homo sapiens] 1235 0.0
gi|218081589 anoctamin 5 isoform b [Homo sapiens] 725 0.0
gi|47106048 anoctamin 5 isoform a [Homo sapiens] 725 0.0
gi|218156299 anoctamin 6 isoform a [Homo sapiens] 724 0.0
gi|218156303 anoctamin 6 isoform b [Homo sapiens] 722 0.0
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 687 0.0
gi|218156307 anoctamin 6 isoform c [Homo sapiens] 684 0.0
gi|218156305 anoctamin 6 isoform c [Homo sapiens] 684 0.0
gi|209862785 anoctamin 2 [Homo sapiens] 681 0.0
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 571 e-162
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 560 e-159
gi|94536803 transmembrane protein 16K [Homo sapiens] 184 4e-46
gi|55741655 anoctamin 8 [Homo sapiens] 114 4e-25
gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] 104 4e-22
gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] 101 4e-21
gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] 83 1e-15
gi|21361159 Wilms' tumour 1-associating protein isoform 1 [Homo ... 33 0.93
gi|9910266 kinesin family member 15 [Homo sapiens] 32 3.5
gi|4757756 annexin A2 isoform 2 [Homo sapiens] 31 6.0
gi|50845386 annexin A2 isoform 2 [Homo sapiens] 31 6.0
gi|50845388 annexin A2 isoform 1 [Homo sapiens] 31 6.0
gi|209862831 annexin A2 isoform 2 [Homo sapiens] 31 6.0
>gi|218084958 anoctamin 4 [Homo sapiens]
Length = 920
Score = 1902 bits (4927), Expect = 0.0
Identities = 920/920 (100%), Positives = 920/920 (100%)
Query: 1 MEASSSGITNGKTKVFHPVAKDVNILFDELEAVSSPCKDDDSLLHPGNLTSTSDDASRLE 60
MEASSSGITNGKTKVFHPVAKDVNILFDELEAVSSPCKDDDSLLHPGNLTSTSDDASRLE
Sbjct: 1 MEASSSGITNGKTKVFHPVAKDVNILFDELEAVSSPCKDDDSLLHPGNLTSTSDDASRLE 60
Query: 61 AGGETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSL 120
AGGETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSL
Sbjct: 61 AGGETVPERNKSNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSL 120
Query: 121 INSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPK 180
INSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPK
Sbjct: 121 INSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPK 180
Query: 181 KPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEE 240
KPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEE
Sbjct: 181 KPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEE 240
Query: 241 GKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQP 300
GKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQP
Sbjct: 241 GKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQP 300
Query: 301 LDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDII 360
LDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDII
Sbjct: 301 LDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDII 360
Query: 361 MCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYD 420
MCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYD
Sbjct: 361 MCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYD 420
Query: 421 WDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICV 480
WDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICV
Sbjct: 421 WDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICV 480
Query: 481 VIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALL 540
VIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALL
Sbjct: 481 VIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALL 540
Query: 541 LTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLE 600
LTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLE
Sbjct: 541 LTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLE 600
Query: 601 ECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQW 660
ECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQW
Sbjct: 601 ECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQW 660
Query: 661 EKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQ 720
EKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQ
Sbjct: 661 EKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQ 720
Query: 721 WRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAG 780
WRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAG
Sbjct: 721 WRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAG 780
Query: 781 QKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTL 840
QKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTL
Sbjct: 781 QKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTL 840
Query: 841 QFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELER 900
QFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELER
Sbjct: 841 QFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELER 900
Query: 901 LQKERKERKKNGKAHHNEWP 920
LQKERKERKKNGKAHHNEWP
Sbjct: 901 LQKERKERKKNGKAHHNEWP 920
>gi|156766084 transmembrane protein 16C [Homo sapiens]
Length = 981
Score = 1235 bits (3195), Expect = 0.0
Identities = 580/849 (68%), Positives = 692/849 (81%), Gaps = 19/849 (2%)
Query: 72 SNGLYFRDGKCRIDYILVYRKSNPQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLH 131
S+G F+DGK RIDYILVYRK+N Q +KR FE+N+RAEGL +EKE ++ + DI+F+K+H
Sbjct: 152 SSGPLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIH 211
Query: 132 APWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLP 191
PW+ L +YAE++N+RMPFR+K YY R K M R+ R + W+ + PM LDK P
Sbjct: 212 IPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFP 271
Query: 192 DLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLL 251
DLEE+DCYT PFS+ RIHHFII+NK+TFF+NATRSRIV+H+L+R KYE G +K+G+ +L+
Sbjct: 272 DLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRKLI 331
Query: 252 TNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEK 311
NGSY AAFP HEG+Y+S I+THG +N+RHLLYE WA WG+WYK+QPLDL+R YFGEK
Sbjct: 332 NNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEK 391
Query: 312 IGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPF 371
IGLYFAWLGWYTGML PAA +GL VF YG+ T+++SQVS+E+C+AT++ MCP+CDK C
Sbjct: 392 IGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSL 451
Query: 372 MRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEE 431
RL+DSC+YAKVT+LFDNG TVFFA+FMA+WATVFLEFWKRRR+++ Y WDLI+WEEEEE
Sbjct: 452 QRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEE 511
Query: 432 EIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIY 491
+RPQFEAKY K E +NPI+GKPEP+Q +DK +RL+VS SGIFFMI +VI AVFG+V+Y
Sbjct: 512 TLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVY 571
Query: 492 RVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTES 551
R+V + FA+FKW I+ Q AT+ AVCINF IIMLLN+ YEK+A LLTNLE PRTES
Sbjct: 572 RLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTES 631
Query: 552 EWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDL 611
EWENSF LKMFLFQFVNLNSS FYIAFFLGRF GHPG Y +L +RWRLEECHPSGCLIDL
Sbjct: 632 EWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDL 691
Query: 612 CMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKDYNLQPMNA 671
C+QMG+IM LKQ WNNFMELGYPLIQNWW+R K+++ S PQWE D+NLQPMN
Sbjct: 692 CLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKR---GIHDASIPQWENDWNLQPMNL 748
Query: 672 YGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKD 731
+GL DEYLEM+LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPL +RA D
Sbjct: 749 HGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATD 808
Query: 732 IGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNAS 791
IGIW GILEGIGIL+VITNAFVIAITSD+IPR VY YKYGPCA E + C+ GYVN S
Sbjct: 809 IGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNS 868
Query: 792 LSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLA 851
LS F +S+ G SG YCRYRDYR PP S PY +TLQ+WH+LAARLA
Sbjct: 869 LSFFDLSEL---------GMGKSG----YCRYRDYRGPPWSSKPYEFTLQYWHILAARLA 915
Query: 852 FIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKN 911
FIIVFEHLVF IK I+YLIPD+PK L DR+RREKYL+QEMMYEAELE LQ ++R+K+
Sbjct: 916 FIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQ---QQRRKS 972
Query: 912 GKAHHNEWP 920
G+ H+EWP
Sbjct: 973 GQPVHHEWP 981
>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
Length = 912
Score = 725 bits (1871), Expect = 0.0
Identities = 377/869 (43%), Positives = 552/869 (63%), Gaps = 56/869 (6%)
Query: 69 RNKSNGLYFRDGKCRIDYILVY-----RKSNPQTEKREVFERNIRAEGLQMEKESSLINS 123
+ + ++FRDG +ID++L Y + + + E+R+ FE N+R GL++E E +
Sbjct: 64 QQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSE 123
Query: 124 D--IIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKK 181
D FVK+HAPWEVL YAE + ++MP + P+ +
Sbjct: 124 DGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLG------------- 170
Query: 182 PMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKY--E 239
P+RL + +TA FS+ R F+I ++ TFF +++R+RIV++IL R + E
Sbjct: 171 PVRLPLSV--KYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIE 228
Query: 240 EGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQ 299
+GK + G+ RLL + +Y +A+PLH+G Y + N R+ L++ WA + +YK Q
Sbjct: 229 DGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSE--PPNPTNERYTLHQNWARFSYFYKEQ 286
Query: 300 PLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT-- 357
PLDL++ Y+GEKIG+YF +LG+YT MLF AA +GL F+YG+ +++H+ S E+C
Sbjct: 287 PLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIG 346
Query: 358 -DIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAV 416
+IMCP+CD+ C + RL+ +C+ +K +HLFDN +TVFFA+FM +W T+FLEFWK+R+A
Sbjct: 347 GQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQAR 406
Query: 417 IAYDWDLIDWEEEEEEI--RPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGI 474
+ Y+WDL+D+EEE++++ RP+FEA K ++N ++ + EPY + +S + +
Sbjct: 407 LEYEWDLVDFEEEQQQLQLRPEFEAM-CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATV 465
Query: 475 FFMICVVIAAVFGIVIYRVVTVSTFAAF-------KWALIRNNSQVATTGTAVCINFCII 527
+ +V+ ++ +++YR+ +TFA+F K Q+ T+ T C+NF +I
Sbjct: 466 TLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVI 525
Query: 528 MLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHP 587
++LN YEK++ +T +E PRT E+E+S TLKMFLFQFVN SS FY+AFF G+F G+P
Sbjct: 526 LILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYP 585
Query: 588 GAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQ 647
G Y L N WR EEC P GCLI+L Q+ IIM KQ + N E YPL NWW RRK R
Sbjct: 586 GKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKART 645
Query: 648 EHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNI 707
K+ + +WE+D++L+ GLF EYLE + QFGF T+FVA+FPLAPLLAL+NNI
Sbjct: 646 N---SEKL-YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNI 701
Query: 708 IEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYA 767
+EIR+DA+K TQ+RR +AS+A IG+W IL G+ +LSV TNAF++A TSD IPRLVY
Sbjct: 702 VEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYY 761
Query: 768 YKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYR 827
Y Y A Q M GYVN SLSVF I+DF N + P S+ +F CRYRDYR
Sbjct: 762 YAYSTNATQP------MTGYVNNSLSVFLIADFPNHTAP-SEKRDFI-----TCRYRDYR 809
Query: 828 DPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKY 887
PP Y + +QFWHVLAA++ FIIV EH+VF +K L++++IPD+PKD+ +R++REK
Sbjct: 810 YPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKL 869
Query: 888 LIQEMMYEAELERLQKERKERKKNGKAHH 916
+ +++++ EL +L KE N A H
Sbjct: 870 MTIKILHDFELNKL-KENLGINSNEFAKH 897
>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
Length = 913
Score = 725 bits (1871), Expect = 0.0
Identities = 377/869 (43%), Positives = 552/869 (63%), Gaps = 56/869 (6%)
Query: 69 RNKSNGLYFRDGKCRIDYILVY-----RKSNPQTEKREVFERNIRAEGLQMEKESSLINS 123
+ + ++FRDG +ID++L Y + + + E+R+ FE N+R GL++E E +
Sbjct: 65 QQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSE 124
Query: 124 D--IIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKK 181
D FVK+HAPWEVL YAE + ++MP + P+ +
Sbjct: 125 DGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLG------------- 171
Query: 182 PMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKY--E 239
P+RL + +TA FS+ R F+I ++ TFF +++R+RIV++IL R + E
Sbjct: 172 PVRLPLSV--KYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIE 229
Query: 240 EGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQ 299
+GK + G+ RLL + +Y +A+PLH+G Y + N R+ L++ WA + +YK Q
Sbjct: 230 DGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSE--PPNPTNERYTLHQNWARFSYFYKEQ 287
Query: 300 PLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT-- 357
PLDL++ Y+GEKIG+YF +LG+YT MLF AA +GL F+YG+ +++H+ S E+C
Sbjct: 288 PLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIG 347
Query: 358 -DIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAV 416
+IMCP+CD+ C + RL+ +C+ +K +HLFDN +TVFFA+FM +W T+FLEFWK+R+A
Sbjct: 348 GQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQAR 407
Query: 417 IAYDWDLIDWEEEEEEI--RPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGI 474
+ Y+WDL+D+EEE++++ RP+FEA K ++N ++ + EPY + +S + +
Sbjct: 408 LEYEWDLVDFEEEQQQLQLRPEFEAM-CKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATV 466
Query: 475 FFMICVVIAAVFGIVIYRVVTVSTFAAF-------KWALIRNNSQVATTGTAVCINFCII 527
+ +V+ ++ +++YR+ +TFA+F K Q+ T+ T C+NF +I
Sbjct: 467 TLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVI 526
Query: 528 MLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHP 587
++LN YEK++ +T +E PRT E+E+S TLKMFLFQFVN SS FY+AFF G+F G+P
Sbjct: 527 LILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYP 586
Query: 588 GAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQ 647
G Y L N WR EEC P GCLI+L Q+ IIM KQ + N E YPL NWW RRK R
Sbjct: 587 GKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKART 646
Query: 648 EHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNI 707
K+ + +WE+D++L+ GLF EYLE + QFGF T+FVA+FPLAPLLAL+NNI
Sbjct: 647 N---SEKL-YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNI 702
Query: 708 IEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYA 767
+EIR+DA+K TQ+RR +AS+A IG+W IL G+ +LSV TNAF++A TSD IPRLVY
Sbjct: 703 VEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYY 762
Query: 768 YKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYR 827
Y Y A Q M GYVN SLSVF I+DF N + P S+ +F CRYRDYR
Sbjct: 763 YAYSTNATQP------MTGYVNNSLSVFLIADFPNHTAP-SEKRDFI-----TCRYRDYR 810
Query: 828 DPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKY 887
PP Y + +QFWHVLAA++ FIIV EH+VF +K L++++IPD+PKD+ +R++REK
Sbjct: 811 YPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKL 870
Query: 888 LIQEMMYEAELERLQKERKERKKNGKAHH 916
+ +++++ EL +L KE N A H
Sbjct: 871 MTIKILHDFELNKL-KENLGINSNEFAKH 898
>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
Length = 910
Score = 724 bits (1868), Expect = 0.0
Identities = 405/902 (44%), Positives = 576/902 (63%), Gaps = 68/902 (7%)
Query: 39 DDDSLLHPGNLTSTS-DDASRLEAGGE-TVPERNKSNG----LYFRDGKCRIDYILVYRK 92
DDD + NL T D LE+ + PE + NG L+F DG+ RID++LVY
Sbjct: 18 DDDGDIVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYED 77
Query: 93 SN-----------PQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYA 141
+ Q KR+ +E N+ GLQ+E S+++ ++FVK+HAPWEVL YA
Sbjct: 78 ESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYA 137
Query: 142 EQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTA 201
E M++++P + P K S ++ F K + +D+ + E + +TA
Sbjct: 138 EIMHIKLPLK------PNDLKNRSSAFGTLNWFT-----KVLSVDESIIKP--EQEFFTA 184
Query: 202 PFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKN--KIGLNRLLTNGSYEAA 259
PF + R++ F I +++ FFN ATRSRIV+ IL R+KY+ N K G+NRL+ +G Y+AA
Sbjct: 185 PFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAA 244
Query: 260 FPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWL 319
FPLH+ +R ++ N R+LLY WA YK QPLDL+R+Y+GEKIG+YFAWL
Sbjct: 245 FPLHDCKFRRQSE--DPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWL 302
Query: 320 GWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT---DIIMCPVCDKYCPFMRLSD 376
G+YT ML AA +G+ FLYG D+ SKEVC IIMCP CD+ CPF +L+
Sbjct: 303 GYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNI 362
Query: 377 SCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQ 436
+C +K +FD+ T+ FAVFM VW T+FLEFWKRR+A + Y+WD ++ ++EE+ RP+
Sbjct: 363 TCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-RPE 421
Query: 437 FEAKYSKKERMNPISGKPE--PYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVV 494
+EA+ + +N I+ + E P+ A+ KC R+ + AS +FF I ++IA+V GI++YR+
Sbjct: 422 YEARCTHVV-INEITQEEERIPFTAW-GKCIRITLCASAVFFWILLIIASVIGIIVYRL- 478
Query: 495 TVSTFAAFKWALIRN-----------NSQVATTGTAVCINFCIIMLLNVLYEKVALLLTN 543
S F F L +N Q AT+ TA I+F IIM+LN +YEKVA+++TN
Sbjct: 479 --SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITN 536
Query: 544 LEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECH 603
E PRT++++ENS T+KMFLFQFVN SS FYIAFF G+F G+PG + + ++R EEC
Sbjct: 537 FELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECD 596
Query: 604 PSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKD 663
P GCL++L Q+ IIM K WNN E+ P I N R + G E KI+ P+WE+D
Sbjct: 597 PGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGR--FHRVSGSE-KIT-PRWEQD 652
Query: 664 YNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRR 723
Y+LQPM GLF EYLEMI+QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K TQ+RR
Sbjct: 653 YHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRR 712
Query: 724 PLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKC 783
+ +A+DIG W I++GI IL+V+TNA +IA TSD IPRLVY + + G+
Sbjct: 713 LVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFS-VPPYGDHTSYT 771
Query: 784 MVGYVNASLSVFRISDFENRSE--PESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQ 841
M GY+N +LS+F+++DF+N+S+ P SD + CRYRD+R PP Y + +
Sbjct: 772 MEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-----TCRYRDFRYPPGHPQEYKHNIY 826
Query: 842 FWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERL 901
+WHV+AA+LAFIIV EH+++ +K ISY IPD+ K + +++REKYL Q++++E L+ +
Sbjct: 827 YWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLHENHLKDM 886
Query: 902 QK 903
K
Sbjct: 887 TK 888
>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
Length = 892
Score = 722 bits (1863), Expect = 0.0
Identities = 393/864 (45%), Positives = 561/864 (64%), Gaps = 62/864 (7%)
Query: 71 KSNGLYFRDGKCRIDYILVYRKSN-----------PQTEKREVFERNIRAEGLQMEKESS 119
K + L+F DG+ RID++LVY + Q KR+ +E N+ GLQ+E S
Sbjct: 38 KPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRS 97
Query: 120 LINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLP 179
+++ ++FVK+HAPWEVL YAE M++++P + P K S ++ F
Sbjct: 98 VLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLK------PNDLKNRSSAFGTLNWFT---- 147
Query: 180 KKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYE 239
K + +D+ + E + +TAPF + R++ F I +++ FFN ATRSRIV+ IL R+KY+
Sbjct: 148 -KVLSVDESIIKP--EQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQ 204
Query: 240 EGKN--KIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYK 297
N K G+NRL+ +G Y+AAFPLH+ +R ++ N R+LLY WA YK
Sbjct: 205 VINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSE--DPSCPNERYLLYREWAHPRSIYK 262
Query: 298 YQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT 357
QPLDL+R+Y+GEKIG+YFAWLG+YT ML AA +G+ FLYG D+ SKEVC
Sbjct: 263 KQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPD 322
Query: 358 ---DIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRR 414
IIMCP CD+ CPF +L+ +C +K +FD+ T+ FAVFM VW T+FLEFWKRR+
Sbjct: 323 IGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQ 382
Query: 415 AVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPE--PYQAFTDKCSRLIVSAS 472
A + Y+WD ++ ++EE+ RP++EA+ + +N I+ + E P+ A+ KC R+ + AS
Sbjct: 383 AELEYEWDTVELQQEEQA-RPEYEARCTHVV-INEITQEEERIPFTAW-GKCIRITLCAS 439
Query: 473 GIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRN-----------NSQVATTGTAVC 521
+FF I ++IA+V GI++YR+ S F F L +N Q AT+ TA
Sbjct: 440 AVFFWILLIIASVIGIIVYRL---SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASI 496
Query: 522 INFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLG 581
I+F IIM+LN +YEKVA+++TN E PRT++++ENS T+KMFLFQFVN SS FYIAFF G
Sbjct: 497 ISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKG 556
Query: 582 RFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWT 641
+F G+PG + + ++R EEC P GCL++L Q+ IIM K WNN E+ P I N
Sbjct: 557 KFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIG 616
Query: 642 RRKVRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLL 701
R + G E KI+ P+WE+DY+LQPM GLF EYLEMI+QFGF T+FVA+FPLAPLL
Sbjct: 617 R--FHRVSGSE-KIT-PRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLL 672
Query: 702 ALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFI 761
AL+NNI+EIR+DA+K TQ+RR + +A+DIG W I++GI IL+V+TNA +IA TSD I
Sbjct: 673 ALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMI 732
Query: 762 PRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSE--PESDGSEFSGTPLK 819
PRLVY + + G+ M GY+N +LS+F+++DF+N+S+ P SD +
Sbjct: 733 PRLVYYWSFS-VPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT----- 786
Query: 820 YCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLR 879
CRYRD+R PP Y + + +WHV+AA+LAFIIV EH+++ +K ISY IPD+ K +
Sbjct: 787 TCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTK 846
Query: 880 DRMRREKYLIQEMMYEAELERLQK 903
+++REKYL Q++++E L+ + K
Sbjct: 847 SKIQREKYLTQKLLHENHLKDMTK 870
>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
sapiens]
Length = 986
Score = 687 bits (1772), Expect = 0.0
Identities = 388/944 (41%), Positives = 546/944 (57%), Gaps = 117/944 (12%)
Query: 67 PERNKSNGLYFRDGKCRIDYILVYRKSNPQTEK--------------------------- 99
P+ GLYFRDG+ ++DYILVY P +
Sbjct: 45 PDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGK 104
Query: 100 -----------------------REVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEV 136
RE +E N+ GL++E++ + FVK+HAPW V
Sbjct: 105 GASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNV 164
Query: 137 LGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEEN 196
L R AE + ++MP +K+Y++ + +I+ + + + K +T+ L
Sbjct: 165 LCREAEFLKLKMP-TKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRL--- 220
Query: 197 DCYTAPFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSY 256
+ PFS+++ H F + +K++FF++ TRS IV+ IL+R + K +G+ LL NG Y
Sbjct: 221 ---SYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVY 277
Query: 257 EAAFPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYF 316
AA+PLH+G Y +N N R LLYE WA +GV+YKYQP+DLVR+YFGEKIGLYF
Sbjct: 278 AAAYPLHDGDYNGENV-----EFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYF 332
Query: 317 AWLGWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVC-QATDIIMCPVCDKYCPFMRLS 375
AWLG YT ML PA+ +G+ VFLYG T+D + S E+C Q +I MCP+CDK C + ++S
Sbjct: 333 AWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMS 392
Query: 376 DSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRP 435
+C A+ +HLFDN ATVFF+VFMA+WA F+E WKR++ + Y WDL +EEEEE ++
Sbjct: 393 SACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKD 452
Query: 436 QFEAKYS--------KKERMNPISGKPEPYQA------------------------FTDK 463
A+Y KKE N + P ++ + D+
Sbjct: 453 HPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDR 512
Query: 464 CSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCIN 523
+ + I FMI V A V G++IYR+ + A +R+N +V T TAV IN
Sbjct: 513 FPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIIN 572
Query: 524 FCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRF 583
+I+LL+ +Y +A LT +E P+TE +E K FL +FVN + FY+AFF GRF
Sbjct: 573 LVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRF 632
Query: 584 TGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQT-WNNFMELGYPLIQNWWTR 642
G PG Y+ + +R+EEC P GCL++LC+Q+ IIM+ KQ NN E+G P ++
Sbjct: 633 VGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRY 692
Query: 643 RKVRQEHGPERKISFPQ---WEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAP 699
K++Q+ P+ + + +E DYNL+P GL EY+EMI+QFGF T+FVA+FPLAP
Sbjct: 693 LKLKQQSPPDHEECVKRKQRYEVDYNLEPFA--GLTPEYMEMIIQFGFVTLFVASFPLAP 750
Query: 700 LLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSD 759
L ALLNNIIEIRLDA KFVT+ RRP+A RAKDIGIWY IL GIG L+VI NAFVI+ TSD
Sbjct: 751 LFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSD 810
Query: 760 FIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLK 819
FIPRLVY Y Y + M G+VN +LS F +SDF+N + P +D + G ++
Sbjct: 811 FIPRLVYLYMY--------SKNGTMHGFVNHTLSSFNVSDFQNGTAP-NDPLDL-GYEVQ 860
Query: 820 YCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLR 879
CRY+DYR+PP S Y + FW VLAARLAF+IVF++LV + + ++IPD+PKD+
Sbjct: 861 ICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDIS 920
Query: 880 DRMRREKYLIQEMMYEAELERLQK----ERKERKKNGKA--HHN 917
++ +EK L+ E+ E ++ Q KER+K+ HHN
Sbjct: 921 QQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHN 964
>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 684 bits (1765), Expect = 0.0
Identities = 388/858 (45%), Positives = 545/858 (63%), Gaps = 68/858 (7%)
Query: 39 DDDSLLHPGNLTSTS-DDASRLEAGGE-TVPERNKSNG----LYFRDGKCRIDYILVYRK 92
DDD + NL T D LE+ + PE + NG L+F DG+ RID++LVY
Sbjct: 18 DDDGDIVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYED 77
Query: 93 SN-----------PQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYA 141
+ Q KR+ +E N+ GLQ+E S+++ ++FVK+HAPWEVL YA
Sbjct: 78 ESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYA 137
Query: 142 EQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTA 201
E M++++P + P K S ++ F K + +D+ + E + +TA
Sbjct: 138 EIMHIKLPLK------PNDLKNRSSAFGTLNWFT-----KVLSVDESIIKP--EQEFFTA 184
Query: 202 PFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKN--KIGLNRLLTNGSYEAA 259
PF + R++ F I +++ FFN ATRSRIV+ IL R+KY+ N K G+NRL+ +G Y+AA
Sbjct: 185 PFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAA 244
Query: 260 FPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWL 319
FPLH+ +R ++ N R+LLY WA YK QPLDL+R+Y+GEKIG+YFAWL
Sbjct: 245 FPLHDCKFRRQSE--DPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWL 302
Query: 320 GWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT---DIIMCPVCDKYCPFMRLSD 376
G+YT ML AA +G+ FLYG D+ SKEVC IIMCP CD+ CPF +L+
Sbjct: 303 GYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNI 362
Query: 377 SCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQ 436
+C +K +FD+ T+ FAVFM VW T+FLEFWKRR+A + Y+WD ++ ++EE+ RP+
Sbjct: 363 TCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-RPE 421
Query: 437 FEAKYSKKERMNPISGKPE--PYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVV 494
+EA+ + +N I+ + E P+ A+ KC R+ + AS +FF I ++IA+V GI++YR+
Sbjct: 422 YEARCTHVV-INEITQEEERIPFTAW-GKCIRITLCASAVFFWILLIIASVIGIIVYRL- 478
Query: 495 TVSTFAAFKWALIRN-----------NSQVATTGTAVCINFCIIMLLNVLYEKVALLLTN 543
S F F L +N Q AT+ TA I+F IIM+LN +YEKVA+++TN
Sbjct: 479 --SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITN 536
Query: 544 LEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECH 603
E PRT++++ENS T+KMFLFQFVN SS FYIAFF G+F G+PG + + ++R EEC
Sbjct: 537 FELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECD 596
Query: 604 PSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKD 663
P GCL++L Q+ IIM K WNN E+ P I N R + G E KI+ P+WE+D
Sbjct: 597 PGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGR--FHRVSGSE-KIT-PRWEQD 652
Query: 664 YNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRR 723
Y+LQPM GLF EYLEMI+QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K TQ+RR
Sbjct: 653 YHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRR 712
Query: 724 PLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKC 783
+ +A+DIG W I++GI IL+V+TNA +IA TSD IPRLVY + + G+
Sbjct: 713 LVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFS-VPPYGDHTSYT 771
Query: 784 MVGYVNASLSVFRISDFENRSE--PESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQ 841
M GY+N +LS+F+++DF+N+S+ P SD + CRYRD+R PP Y + +
Sbjct: 772 MEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-----TCRYRDFRYPPGHPQEYKHNIY 826
Query: 842 FWHVLAARLAFIIVFEHL 859
+WHV+AA+LAFIIV E+L
Sbjct: 827 YWHVIAAKLAFIIVMEYL 844
>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 684 bits (1765), Expect = 0.0
Identities = 388/858 (45%), Positives = 545/858 (63%), Gaps = 68/858 (7%)
Query: 39 DDDSLLHPGNLTSTS-DDASRLEAGGE-TVPERNKSNG----LYFRDGKCRIDYILVYRK 92
DDD + NL T D LE+ + PE + NG L+F DG+ RID++LVY
Sbjct: 18 DDDGDIVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYED 77
Query: 93 SN-----------PQTEKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYA 141
+ Q KR+ +E N+ GLQ+E S+++ ++FVK+HAPWEVL YA
Sbjct: 78 ESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYA 137
Query: 142 EQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTA 201
E M++++P + P K S ++ F K + +D+ + E + +TA
Sbjct: 138 EIMHIKLPLK------PNDLKNRSSAFGTLNWFT-----KVLSVDESIIKP--EQEFFTA 184
Query: 202 PFSQQRIHHFIIHNKETFFNNATRSRIVHHILQRIKYEEGKN--KIGLNRLLTNGSYEAA 259
PF + R++ F I +++ FFN ATRSRIV+ IL R+KY+ N K G+NRL+ +G Y+AA
Sbjct: 185 PFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAA 244
Query: 260 FPLHEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWL 319
FPLH+ +R ++ N R+LLY WA YK QPLDL+R+Y+GEKIG+YFAWL
Sbjct: 245 FPLHDCKFRRQSE--DPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWL 302
Query: 320 GWYTGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQAT---DIIMCPVCDKYCPFMRLSD 376
G+YT ML AA +G+ FLYG D+ SKEVC IIMCP CD+ CPF +L+
Sbjct: 303 GYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNI 362
Query: 377 SCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQ 436
+C +K +FD+ T+ FAVFM VW T+FLEFWKRR+A + Y+WD ++ ++EE+ RP+
Sbjct: 363 TCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQA-RPE 421
Query: 437 FEAKYSKKERMNPISGKPE--PYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVV 494
+EA+ + +N I+ + E P+ A+ KC R+ + AS +FF I ++IA+V GI++YR+
Sbjct: 422 YEARCTHVV-INEITQEEERIPFTAW-GKCIRITLCASAVFFWILLIIASVIGIIVYRL- 478
Query: 495 TVSTFAAFKWALIRN-----------NSQVATTGTAVCINFCIIMLLNVLYEKVALLLTN 543
S F F L +N Q AT+ TA I+F IIM+LN +YEKVA+++TN
Sbjct: 479 --SVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITN 536
Query: 544 LEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECH 603
E PRT++++ENS T+KMFLFQFVN SS FYIAFF G+F G+PG + + ++R EEC
Sbjct: 537 FELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECD 596
Query: 604 PSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHGPERKISFPQWEKD 663
P GCL++L Q+ IIM K WNN E+ P I N R + G E KI+ P+WE+D
Sbjct: 597 PGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGR--FHRVSGSE-KIT-PRWEQD 652
Query: 664 YNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRR 723
Y+LQPM GLF EYLEMI+QFGF T+FVA+FPLAPLLAL+NNI+EIR+DA+K TQ+RR
Sbjct: 653 YHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRR 712
Query: 724 PLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKC 783
+ +A+DIG W I++GI IL+V+TNA +IA TSD IPRLVY + + G+
Sbjct: 713 LVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFS-VPPYGDHTSYT 771
Query: 784 MVGYVNASLSVFRISDFENRSE--PESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQ 841
M GY+N +LS+F+++DF+N+S+ P SD + CRYRD+R PP Y + +
Sbjct: 772 MEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-----TCRYRDFRYPPGHPQEYKHNIY 826
Query: 842 FWHVLAARLAFIIVFEHL 859
+WHV+AA+LAFIIV E+L
Sbjct: 827 YWHVIAAKLAFIIVMEYL 844
>gi|209862785 anoctamin 2 [Homo sapiens]
Length = 998
Score = 681 bits (1757), Expect = 0.0
Identities = 357/829 (43%), Positives = 519/829 (62%), Gaps = 51/829 (6%)
Query: 98 EKREVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYL 157
E+RE FE N+ GL++EK+ + IFV++HAPW+VL R AE + +++P +K+Y +
Sbjct: 153 EQREEFEHNLMEAGLELEKDLENKSQGSIFVRIHAPWQVLAREAEFLKIKVP-TKKMYEI 211
Query: 158 PRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFIIHNKE 217
+ + + L + + +L + PFS+++++ + I K+
Sbjct: 212 KAGGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNL------SYPFSREKMYLYNIQEKD 265
Query: 218 TFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHG 277
TFF+NATRSRIVH IL+R N +G+N L+ N YEAA+PLH+G Y S
Sbjct: 266 TFFDNATRSRIVHEILKRTACSRANNTMGINSLIANNIYEAAYPLHDGEYDSPEDDM--- 322
Query: 278 AENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVF 337
N R LLY+ WA +GV+YK+QP+DL+R+YFGEKIGLYFAWLG YT L P++ IG+ VF
Sbjct: 323 --NDRKLLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVF 380
Query: 338 LYGVTTLDHSQVSKEVC-QATDIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFA 396
LYG T++ S+E+C Q MCP+CDK C + LS +C A+ +HLFDN ATVFF+
Sbjct: 381 LYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFS 440
Query: 397 VFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEI----RPQFEAKYSKKERMNPISG 452
+FMA+WAT+FLE WKR + + Y WDL EEEEE RP++E K +K
Sbjct: 441 IFMALWATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQS 500
Query: 453 KPEPYQAFTDKCSR---------------LIVSASGIFFMICVVIAAVFGIVIYRVVTVS 497
+ + T +C +++ + I FMI + + VFG+++YR+ T +
Sbjct: 501 AVQKLETNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAA 560
Query: 498 TFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSF 557
+ K R+N +V T TAV IN +I++L+ +Y VA LT +E P+TE +E
Sbjct: 561 ALSLNK--ATRSNVRVTVTATAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERL 618
Query: 558 TLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGI 617
LK FL +FVN S FY+AFF GRF G PG+Y+ + + +R+EEC P GCL++LC+Q+ I
Sbjct: 619 ILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSI 678
Query: 618 IMVLKQT-WNNFMELGYPLIQNWWTRRKVRQEHGPERKISFP---QWEKDYNLQPMNAYG 673
IM+ KQ NN E+G P ++ + + K E G QW+ DY+L+P G
Sbjct: 679 IMLGKQLIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYT--G 736
Query: 674 LFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIG 733
L EY+EMI+QFGF T+FVA+FPLAP+ ALLNN+IE+RLDA KFVT+ RRP A R KDIG
Sbjct: 737 LTPEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIG 796
Query: 734 IWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLS 793
IW+ IL GIG SVI+NAFVIAITSDFIPRLVY Y Y + + G+VN +LS
Sbjct: 797 IWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSY--------SHNGTLHGFVNHTLS 848
Query: 794 VFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFI 853
F +S + ++PE+ S+F +++CR++DYR+PP + PY ++ Q+W +L+ARLAF+
Sbjct: 849 FFNVSQLKEGTQPEN--SQFD-QEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFV 905
Query: 854 IVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQ 902
I+F++LV + L+ ++IPD+P D+ D++++EK L+ + + E E+L+
Sbjct: 906 IIFQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLVDFFLKEEHEKLK 954
>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
sapiens]
Length = 933
Score = 571 bits (1471), Expect = e-162
Identities = 328/827 (39%), Positives = 478/827 (57%), Gaps = 54/827 (6%)
Query: 100 REVFERNIRAEGLQMEKESSLI-NSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLP 158
RE F N+RA GL ++++ N+ + + L A W VL YAE + +++P + LP
Sbjct: 141 RETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQE----LP 196
Query: 159 RRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFI-IHNKE 217
+ S + WL + L E +PD+ + Y+ F ++ F+ N++
Sbjct: 197 NQASNWS------AGLLAWLGIPNVLL--EVVPDVPP-EYYSCRFRVNKLPRFLGSDNQD 247
Query: 218 TFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTH 276
TFF + R +I+ IL + Y E KN +G+++LL G AAFPLH+G +++
Sbjct: 248 TFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQA 307
Query: 277 GAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFV 336
N R +L++ WA WG W KYQPLD VRRYFGEK+ LYFAWLG+YTG L PAA +G V
Sbjct: 308 PRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLV 367
Query: 337 FLYGVTTLDHSQVSKEVCQATDII-MCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFF 395
FL G + ++E+C + D MCP+C CPF LS +C A+ LFD+G TVFF
Sbjct: 368 FLVGCFLVFSDIPTQELCGSKDSFEMCPLCLD-CPFWLLSSACALAQAGRLFDHGGTVFF 426
Query: 396 AVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPE 455
++FMA+WA + LE+WKR+ A +AY WD D+E+ EE RPQF A + NPI+G+ E
Sbjct: 427 SLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAAS-APMTAPNPITGEDE 485
Query: 456 PYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVAT 515
PY + R++ + I M+ VV+ + I++YR + + L+ +
Sbjct: 486 PYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIA 545
Query: 516 TGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFY 575
+ T +N I++L+ +Y +A +LT E RT++++E++FTLK+F+FQFVN SS Y
Sbjct: 546 SLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVY 605
Query: 576 IAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPL 635
IAFF GRF G+PG Y L R EEC GCLI+L ++ +IMV KQ NN E+ P
Sbjct: 606 IAFFKGRFVGYPGNYHTLFGV-RNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPK 664
Query: 636 IQNWWTRRKVRQEH---GPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFV 692
++ WW + ++R + G S WE DY L P GLFDEYLEM+LQFGF TIFV
Sbjct: 665 LKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFV 722
Query: 693 AAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAF 752
AA PLAPL ALLNN +EIRLDA KFV ++RRP+A RA+DIGIW+ IL G+ L+VI+NAF
Sbjct: 723 AACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAF 782
Query: 753 VIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSE 812
++A +SDF+PR Y + + G++N +L+ S
Sbjct: 783 LLAFSSDFLPRAYYRW----------TRAHDLRGFLNFTLA--------------RAPSS 818
Query: 813 FSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIP 872
F+ + CRYR +RD Y+ +W++LA RLAF+IVFEH+VF + L+ L+P
Sbjct: 819 FAAAHNRTCRYRAFRDDDGH-----YSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVP 873
Query: 873 DLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKAHHNEW 919
D+P+ + +++RE YL ++ + E E+ K+ + G + W
Sbjct: 874 DIPESVEIKVKREYYLAKQALAENEVLFGTNGTKDEQPEGSELSSHW 920
>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
Length = 782
Score = 560 bits (1444), Expect = e-159
Identities = 297/668 (44%), Positives = 405/668 (60%), Gaps = 51/668 (7%)
Query: 225 RSRIVHHILQRIKYEEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTHGAENHRHL 284
R RIV+ ++ K G+ L+ +G +EA FPLH+G R K +
Sbjct: 119 RIRIVNFVVMNNKTSAGET---FEDLMKDGVFEARFPLHKGEGRLKKT------------ 163
Query: 285 LYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTL 344
WA W ++ QP+D +R YFGEK+ LYF WLGWYT ML PAA GL VFL G +
Sbjct: 164 ----WARWRHMFREQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLF 219
Query: 345 DHSQVSKEVCQATDIIMCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWAT 404
+ SQ+SKE+C+A DI+MCP+ D + RLS++C +AK+THLFDN TV FA+FMA+WAT
Sbjct: 220 EASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWAT 279
Query: 405 VFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKC 464
VFLE WKR+RA + WDL W+EE+EE+ Q +N K PYQ +
Sbjct: 280 VFLEIWKRQRARVVLHWDLYVWDEEQEEMALQL---------INCPDYKLRPYQHSYLRS 330
Query: 465 SRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINF 524
+ ++V MIC++I +V+YRV+ + F++ + A T +++
Sbjct: 331 TVILVLT---LLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHY 387
Query: 525 CIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFT 584
I+++ + VAL L + E PRT SE E+ FT++ F QF SS YIAF LGR
Sbjct: 388 VTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRIN 447
Query: 585 GHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRK 644
GHPG RL W+LEECH SGC++DL +QM IIM LKQT +N +E P W K
Sbjct: 448 GHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVP-----WVTHK 502
Query: 645 VRQEHGPE-----RKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAP 699
R E R W ++Y L P+N + LFDE++EM++Q+GFTTIFVAAFPLAP
Sbjct: 503 CRSLRASESGHLPRDPELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAP 562
Query: 700 LLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSD 759
LLAL +N++EIRLDA K V RR + +AKDIG W +LE IG+L+VI N VIA TS+
Sbjct: 563 LLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSE 622
Query: 760 FIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLK 819
FIPR+VY Y+Y PC +G + C+ GYVN SLSVF DF+ + DG E S +
Sbjct: 623 FIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQ-----DPDGIEGSEN-VT 676
Query: 820 YCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLR 879
CRYRDYR+PP Y ++ QFW +LA RLAF+I+FEH+ CIK + ++ +PD+P+ ++
Sbjct: 677 LCRYRDYRNPP----DYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVK 732
Query: 880 DRMRREKY 887
+++ KY
Sbjct: 733 NKVLEVKY 740
>gi|94536803 transmembrane protein 16K [Homo sapiens]
Length = 660
Score = 184 bits (466), Expect = 4e-46
Identities = 162/571 (28%), Positives = 249/571 (43%), Gaps = 135/571 (23%)
Query: 215 NKETFFNNATRSRIVHHILQRIKYEEGK------------NKIGLNRLLTNGSYEAAFPL 262
N + F A I+ H L+ ++ ++ K K L RLLT+G FPL
Sbjct: 114 NNDDFLTMAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLTSGIVIQVFPL 173
Query: 263 HEGSYRSKNSIRTHGAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWY 322
H+ K L + W + KYQP+D +R YFGE I LYF +L ++
Sbjct: 174 HDSEALKK--------------LEDTWYTRFA-LKYQPIDSIRGYFGETIALYFGFLEYF 218
Query: 323 TGMLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPFMRLSDSCVYAK 382
T L P A IGL +L+ + DKY
Sbjct: 219 TFALIPMAVIGLPYYLF---------------------VWEDYDKY-------------- 243
Query: 383 VTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYS 442
V FA F +W+TV LE WKR A + Y W + + + EE RP F
Sbjct: 244 ----------VIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGVLG 293
Query: 443 KKERMNPISGKPEP-YQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAA 501
+N I+GK EP Y ++ + +VS F +C+ + ++ ++IY + V
Sbjct: 294 ----INSITGKEEPLYPSYKRQLRIYLVSLP--FVCLCLYFS-LYVMMIYFDMEV----- 341
Query: 502 FKWAL-IRNNSQVATTGTAV----CINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENS 556
WAL + NS T + I +I ++N LY A LT+ E R ES ++N
Sbjct: 342 --WALGLHENSGSEWTSVLLYVPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNH 399
Query: 557 FTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMG 616
LK+ +F F+N +S FYIAF L ++L+ + +
Sbjct: 400 LILKVLVFNFLNCFASLFYIAFVL--------KDMKLLRQ-----------------SLA 434
Query: 617 IIMVLKQTWNNFMELGYPLIQNWWTRRKVRQEHG--PERKISFPQWEKDYNL-------Q 667
+++ Q N ME P +W +RK HG +RK+ + + D L +
Sbjct: 435 TLLITSQILNQIMESFLP----YWLQRK----HGVRVKRKVQALKADIDATLYEQVILEK 486
Query: 668 PMNAY-GLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLA 726
M Y G FD+YLE+ LQFG+ ++F +PLA A+LNN E+ DA K ++RP +
Sbjct: 487 EMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFS 546
Query: 727 SRAKDIGIWYGILEGIGILSVITNAFVIAIT 757
+ +IG+W E + ++SV+TN +I ++
Sbjct: 547 EPSANIGVWQLAFETMSVISVVTNCALIGMS 577
Score = 33.1 bits (74), Expect = 1.2
Identities = 11/58 (18%), Positives = 34/58 (58%)
Query: 850 LAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKE 907
+ ++ EH + +K ++++ IPD P+ ++ ++ R ++ E + + +++ + + KE
Sbjct: 592 ILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKE 649
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 114 bits (285), Expect = 4e-25
Identities = 110/386 (28%), Positives = 165/386 (42%), Gaps = 89/386 (23%)
Query: 211 FIIHNKET---FFNNATRSRIVHHILQRIKYEEGK---------NKIGLNRLLTNGSYEA 258
FI N E+ FF + R I+ LQ ++ ++G+ ++ + L G +
Sbjct: 148 FIYENVESELRFFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQ 207
Query: 259 AFPLHEGSYRSKNSIRTHGAENHRHLLYECWASW-GVWYKYQPLDLVRRYFGEKIGLYFA 317
FP+HE + +L SW + QPLD + YFG KI +YFA
Sbjct: 208 VFPVHE-----------------QRILNRLMKSWVQAVCENQPLDDICDYFGVKIAMYFA 250
Query: 318 WLGWYTG-MLFPAAFIGLFVFLYGVTTLDHSQVSKEVCQATDIIMCPVCDKYCPFMRLSD 376
WLG+YT M++PA F + LY T D Q S++V
Sbjct: 251 WLGFYTSAMVYPAVFGSV---LYTFTEAD--QTSRDV----------------------- 282
Query: 377 SCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEE-EEIRP 435
SCV FA+F +W+T+FLE WKRR A +AY W +D E EE RP
Sbjct: 283 SCVV--------------FALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRP 328
Query: 436 QFEAKYSKKERMNPISGKPE-PYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVV 494
QF R++PI+ E Y + +L+VS + V + G + +
Sbjct: 329 QFRGV----RRISPITRAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQEL 384
Query: 495 TVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWE 554
+S + A +A ++ + Y+K+A+ L ++E R ES +E
Sbjct: 385 VLSVKGLPRLARFLPKVMLAL----------LVSVSAEGYKKLAIWLNDMENYRLESAYE 434
Query: 555 NSFTLKMFLFQFVNLNSSTFYIAFFL 580
+K+ LFQFVN S FYI F+L
Sbjct: 435 KHLIIKVVLFQFVNSYLSLFYIGFYL 460
Score = 88.2 bits (217), Expect = 3e-17
Identities = 49/120 (40%), Positives = 71/120 (59%), Gaps = 7/120 (5%)
Query: 641 TRRKVRQEHG-----PERKISFPQWEKDYNLQPMNAY-GLFDEYLEMILQFGFTTIFVAA 694
TRR+ RQ PE + S PQ + M Y F +Y EM +QFG+ +F +A
Sbjct: 706 TRRQRRQNRSSWIDPPEEEHS-PQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSA 764
Query: 695 FPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVI 754
FPLA L AL+NN+IEIR DA+K T +RP R + IG W ++E +G+L+++ N ++I
Sbjct: 765 FPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLI 824
Score = 39.3 bits (90), Expect = 0.017
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 4/80 (5%)
Query: 843 WHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMM----YEAEL 898
W A + ++V EH +K+LI IPD+P + + M + +Y +E +A+
Sbjct: 836 WLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQH 895
Query: 899 ERLQKERKERKKNGKAHHNE 918
Q++R+ R++ + H E
Sbjct: 896 RYQQQQRRRREEEERQRHAE 915
>gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
Length = 719
Score = 104 bits (259), Expect = 4e-22
Identities = 136/539 (25%), Positives = 206/539 (38%), Gaps = 176/539 (32%)
Query: 382 KVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEE----------- 430
K++ LFD+ TVFF++FM+ W + A +A+ WD D++++E
Sbjct: 254 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWD 313
Query: 431 ------EEIRP---------------------QFEAKYSKKERMNPISGKPEPYQAFTDK 463
+E+ P QF A + + NP++G EPY
Sbjct: 314 CSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAA-LALQMTQNPVTGLKEPYFQPHSC 372
Query: 464 CSRLIVSASGIFFMICVVIAAVFGIVIYR-VVTVSTFAAFKWALIRNNSQVATTGTAVCI 522
S L+ S++ I ++CVV+ + ++IY +++++ F TG +V
Sbjct: 373 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFH---------------TGNSV-- 415
Query: 523 NFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGR 582
++ NVL W N M + S +F + FL
Sbjct: 416 ---LMTQANVL-------------------WGNGGDASM------KMPSLSFSVCQFL-- 445
Query: 583 FTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMEL----GYPLIQN 638
+ L++ +C P GC I + Q+ IIMV KQ N+ E G P
Sbjct: 446 -------FFSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLGGGP---- 494
Query: 639 WWTRRKVRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLA 698
GP+ P+ LQFGF TIFV AF LA
Sbjct: 495 -----------GPDTPC-LPE-----------------------LQFGFITIFVGAFLLA 519
Query: 699 PLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITS 758
PL LLNN +EI LDA+KF+ +++RP+A R G ++ TNA
Sbjct: 520 PLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA------- 572
Query: 759 DFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPL 818
RL Y GQG+ ++G + F + E P+
Sbjct: 573 --RSRLGYWLN-----GQGQ-----ILGRRRGGNAGFGVEIREPLQTPQP---------- 610
Query: 819 KYCRYRDYRDPPHSLVPYGYTLQFWHVLA--ARLAFIIVFEHLVFCIKHLISYLIPDLP 875
RY+ RD V L +W +LA L FII FE++VF L+PD+P
Sbjct: 611 ---RYKASRD-----VGVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 661
Score = 39.7 bits (91), Expect = 0.013
Identities = 15/23 (65%), Positives = 16/23 (69%)
Query: 280 NHRHLLYECWASWGVWYKYQPLD 302
N LLY WA WG W+KYQPLD
Sbjct: 227 NSCQLLYPYWACWGYWHKYQPLD 249
>gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]
Length = 723
Score = 101 bits (251), Expect = 4e-21
Identities = 136/546 (24%), Positives = 207/546 (37%), Gaps = 176/546 (32%)
Query: 375 SDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEE---- 430
+++ V+ V L D TVFF++FM+ W + A +A+ WD D++++E
Sbjct: 251 TNTLVWVAVEGLGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPS 310
Query: 431 -------------EEIRP---------------------QFEAKYSKKERMNPISGKPEP 456
+E+ P QF A + + NP++G EP
Sbjct: 311 SAPHHWDCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAA-LALQMTQNPVTGLKEP 369
Query: 457 YQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYR-VVTVSTFAAFKWALIRNNSQVAT 515
Y S L+ S++ I ++CVV+ + ++IY +++++ F
Sbjct: 370 YFQPHSCLSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFH--------------- 414
Query: 516 TGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFY 575
TG +V ++ NVL W N M + S +F
Sbjct: 415 TGNSV-----LMTQANVL-------------------WGNGGDASM------KMPSLSFS 444
Query: 576 IAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMEL---- 631
+ FL + L++ +C P GC I + Q+ IIMV KQ N+ E
Sbjct: 445 VCQFL---------FFSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFVGLG 495
Query: 632 GYPLIQNWWTRRKVRQEHGPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIF 691
G P GP+ P+ LQFGF TIF
Sbjct: 496 GGP---------------GPDTPC-LPE-----------------------LQFGFITIF 516
Query: 692 VAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNA 751
V AF LAPL LLNN +EI LDA+KF+ +++RP+A R G ++ TNA
Sbjct: 517 VGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGSDCSCWRPCELILPRTNA 576
Query: 752 FVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGS 811
RL Y GQG+ ++G + F + E P+
Sbjct: 577 ---------RSRLGYWLN-----GQGQ-----ILGRRRGGNAGFGVEIREPLQTPQP--- 614
Query: 812 EFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLA--ARLAFIIVFEHLVFCIKHLISY 869
RY+ RD V L +W +LA L FII FE++VF
Sbjct: 615 ----------RYKASRD-----VGVNLALFYWKLLAVHVHLGFIIAFENVVFFFLCPNDR 659
Query: 870 LIPDLP 875
L+PD+P
Sbjct: 660 LVPDVP 665
>gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]
Length = 494
Score = 83.2 bits (204), Expect = 1e-15
Identities = 121/503 (24%), Positives = 195/503 (38%), Gaps = 125/503 (24%)
Query: 382 KVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKY 441
K++ LFD+ TVFF++FM+ W + A +A+ WD D+++ +E P
Sbjct: 50 KLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQD--QEAMP------ 101
Query: 442 SKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAA 501
S P + +D + ++ +S + C + +T +
Sbjct: 102 ---------SSAPHHWDC-SDFQDQEVMPSSALHHWDCSDFQDQEFAALALQMTQNPVTG 151
Query: 502 FKWALIRNNS---QVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFT 558
K + +S + T+ A+ C++M+ V++++ + +
Sbjct: 152 LKEPYFQPHSCLSHLLTSSAAILTVLCVVMIF-----LVSVII-----------YHGIIS 195
Query: 559 LKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGII 618
+ MF + +S + G P A +++ + ++C P GC I + Q+ II
Sbjct: 196 IAMF-----HTGNSVLMTQANVLWGNGGPKALSKVLCVCQ-QQCGPGGCHIQVTQQLIII 249
Query: 619 MVLKQTWNNFMEL----GYPLIQNWWTRRKVRQEHGPERKISFPQWEKDYNLQPMNAYGL 674
MV KQ N+ E G P GP+ P+
Sbjct: 250 MVGKQLLNHMEEFVGLGGGP---------------GPDTPC-LPE--------------- 278
Query: 675 FDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGI 734
LQFGF TIFV AF LAPL LLNN +EI LDA+KF+ +++RP+A R G
Sbjct: 279 --------LQFGFITIFVGAFLLAPLFTLLNNRVEIGLDAHKFLCKYQRPMAGRGWTSGS 330
Query: 735 WYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSV 794
++ TNA RL Y GQG+ ++G +
Sbjct: 331 DCSCWRPCELILPRTNA---------RSRLGYWLN-----GQGQ-----ILGRRRGGNAG 371
Query: 795 FRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLA--ARLAF 852
F + E P+ RY+ RD V L +W +LA L F
Sbjct: 372 FGVEIREPLQTPQP-------------RYKASRD-----VGVNLALFYWKLLAVHVHLGF 413
Query: 853 IIVFEHLVFCIKHLISYLIPDLP 875
II FE++VF L+PD+P
Sbjct: 414 IIAFENVVFFFLCPNDRLVPDVP 436
Score = 39.7 bits (91), Expect = 0.013
Identities = 15/23 (65%), Positives = 16/23 (69%)
Query: 280 NHRHLLYECWASWGVWYKYQPLD 302
N LLY WA WG W+KYQPLD
Sbjct: 23 NSCQLLYPYWACWGYWHKYQPLD 45
>gi|21361159 Wilms' tumour 1-associating protein isoform 1 [Homo
sapiens]
Length = 396
Score = 33.5 bits (75), Expect = 0.93
Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 23 VNILFDELEAVSSPCKDDDSLLHPGNLTSTSDDASRLEA----GGETVPERNKSNGL 75
VN L E+V SP ++SL H N T +S D +A G TV R+ NGL
Sbjct: 329 VNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQEEKAVSGKGNRTVGSRHVQNGL 385
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 31.6 bits (70), Expect = 3.5
Identities = 44/183 (24%), Positives = 80/183 (43%), Gaps = 42/183 (22%)
Query: 47 GNLTSTSDDASRLE------AGGETVPE------RNKSNGL-YFRDGKCRIDYILVYRKS 93
GN++ + RL+ A G+T PE + K+N + YF++ +L ++KS
Sbjct: 375 GNVSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKTNYMEYFQEA------MLFFKKS 428
Query: 94 NPQTEKREVFERNIRAEGLQMEKESSLINSDII----------FVKLH-------APWEV 136
+ EK+ + E+ + E L ++KE + ++ +I KLH P E
Sbjct: 429 --EQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEKLHKESRGGFLPEEQ 486
Query: 137 LGRYAEQMNVRMPFRRKIYYLPRRYKFMSR---IDKQISRFRRWLP-KKPMRLDKETLPD 192
+E N R +I + PR K+ + ++ R R P K+ +D +T+
Sbjct: 487 DRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQEMDAQTIAK 546
Query: 193 LEE 195
LE+
Sbjct: 547 LEK 549
>gi|4757756 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 30.8 bits (68), Expect = 6.0
Identities = 17/59 (28%), Positives = 34/59 (57%)
Query: 856 FEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKA 914
F +LV CI++ Y L ++ + R+K LI+ M+ +E++ L+ + ++K GK+
Sbjct: 256 FLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 314
>gi|50845386 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 30.8 bits (68), Expect = 6.0
Identities = 17/59 (28%), Positives = 34/59 (57%)
Query: 856 FEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKA 914
F +LV CI++ Y L ++ + R+K LI+ M+ +E++ L+ + ++K GK+
Sbjct: 256 FLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 314
>gi|50845388 annexin A2 isoform 1 [Homo sapiens]
Length = 357
Score = 30.8 bits (68), Expect = 6.0
Identities = 17/59 (28%), Positives = 34/59 (57%)
Query: 856 FEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKA 914
F +LV CI++ Y L ++ + R+K LI+ M+ +E++ L+ + ++K GK+
Sbjct: 274 FLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 332
>gi|209862831 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 30.8 bits (68), Expect = 6.0
Identities = 17/59 (28%), Positives = 34/59 (57%)
Query: 856 FEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKA 914
F +LV CI++ Y L ++ + R+K LI+ M+ +E++ L+ + ++K GK+
Sbjct: 256 FLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 314
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,132,516
Number of Sequences: 37866
Number of extensions: 1591635
Number of successful extensions: 5954
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 5798
Number of HSP's gapped (non-prelim): 49
length of query: 920
length of database: 18,247,518
effective HSP length: 112
effective length of query: 808
effective length of database: 14,006,526
effective search space: 11317273008
effective search space used: 11317273008
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.