Guide to the Human Genome
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Search of human proteins with 217330622

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5
[Homo sapiens]
         (880 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Ho...  1767   0.0  
gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Ho...  1767   0.0  
gi|58082081 phosphoinositide-3-kinase, regulatory subunit 6 [Hom...   119   1e-26
gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]     41   0.004
gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]    40   0.012
gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens]    40   0.012
gi|55741677 SET domain containing 1A [Homo sapiens]                    39   0.016
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         39   0.021
gi|23397642 GREB1 protein isoform a [Homo sapiens]                     38   0.047
gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo sapi...    37   0.062
gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo sapi...    37   0.062
gi|166795264 AE binding protein 2 isoform b [Homo sapiens]             37   0.062
gi|166795262 AE binding protein 2 isoform a [Homo sapiens]             37   0.062
gi|54859722 nucleoporin 160kDa [Homo sapiens]                          37   0.081
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          37   0.081
gi|168823443 RAD54-like 2 [Homo sapiens]                               37   0.11 
gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]               36   0.14 
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    36   0.14 
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           36   0.14 
gi|210032580 SET domain containing 1B [Homo sapiens]                   36   0.14 
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        36   0.14 
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom...    36   0.18 
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom...    36   0.18 
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]               35   0.23 
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   35   0.23 
gi|17975763 myelin transcription factor 1 [Homo sapiens]               35   0.23 
gi|122937247 unc-13 homolog A [Homo sapiens]                           35   0.23 
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    35   0.31 
gi|38373682 pleckstrin homology domain containing family G membe...    35   0.31 
gi|111154084 pleckstrin homology domain containing family G memb...    35   0.31 

>gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
           sapiens]
          Length = 880

 Score = 1767 bits (4577), Expect = 0.0
 Identities = 880/880 (100%), Positives = 880/880 (100%)

Query: 1   MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE 60
           MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE
Sbjct: 1   MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE 60

Query: 61  QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC 120
           QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC
Sbjct: 61  QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC 120

Query: 121 SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN 180
           SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN
Sbjct: 121 SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN 180

Query: 181 KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA 240
           KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA
Sbjct: 181 KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA 240

Query: 241 SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI 300
           SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI
Sbjct: 241 SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI 300

Query: 301 LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS 360
           LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS
Sbjct: 301 LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS 360

Query: 361 LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK 420
           LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK
Sbjct: 361 LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK 420

Query: 421 FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP 480
           FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP
Sbjct: 421 FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP 480

Query: 481 QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR 540
           QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR
Sbjct: 481 QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR 540

Query: 541 LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW 600
           LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW
Sbjct: 541 LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW 600

Query: 601 EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL 660
           EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL
Sbjct: 601 EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL 660

Query: 661 YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG 720
           YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG
Sbjct: 661 YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG 720

Query: 721 DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV 780
           DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV
Sbjct: 721 DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV 780

Query: 781 VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK 840
           VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK
Sbjct: 781 VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK 840

Query: 841 PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP 880
           PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP
Sbjct: 841 PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP 880


>gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
           sapiens]
          Length = 880

 Score = 1767 bits (4577), Expect = 0.0
 Identities = 880/880 (100%), Positives = 880/880 (100%)

Query: 1   MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE 60
           MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE
Sbjct: 1   MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLE 60

Query: 61  QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC 120
           QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC
Sbjct: 61  QILQKTREVQEKGTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYC 120

Query: 121 SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN 180
           SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN
Sbjct: 121 SICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEFLAVAN 180

Query: 181 KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA 240
           KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA
Sbjct: 181 KLSTPGHSPHSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQELA 240

Query: 241 SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI 300
           SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI
Sbjct: 241 SGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDI 300

Query: 301 LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS 360
           LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS
Sbjct: 301 LQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS 360

Query: 361 LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK 420
           LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK
Sbjct: 361 LASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQK 420

Query: 421 FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP 480
           FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP
Sbjct: 421 FIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLP 480

Query: 481 QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR 540
           QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR
Sbjct: 481 QPKLGTQLPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRR 540

Query: 541 LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW 600
           LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW
Sbjct: 541 LENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPW 600

Query: 601 EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL 660
           EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL
Sbjct: 601 EESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLPILADMLL 660

Query: 661 YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG 720
           YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG
Sbjct: 661 YYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDG 720

Query: 721 DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV 780
           DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV
Sbjct: 721 DREAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSMEALTLNLTEV 780

Query: 781 VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK 840
           VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK
Sbjct: 781 VKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVVRCEVSPCYK 840

Query: 841 PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP 880
           PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP
Sbjct: 841 PEKSDLSSPPQTPPDLPAQAAPDLCSLLCLPIMTFSGALP 880


>gi|58082081 phosphoinositide-3-kinase, regulatory subunit 6 [Homo
           sapiens]
          Length = 754

 Score =  119 bits (298), Expect = 1e-26
 Identities = 115/415 (27%), Positives = 174/415 (41%), Gaps = 76/415 (18%)

Query: 490 SWLLAPASRPQRRRPFLSGDEDPKAS---TLRVVVFGSDRISGKVARAYSNLRRLENNRP 546
           SW   P    +  RP   G+  P  S   T RV+V G DR+ G++A+AY  LR+ E  + 
Sbjct: 386 SWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDRMLGRLAQAYHRLRKRETQKF 445

Query: 547 LLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTND 606
            LT    LQ +Y+PV                  P  P  S R    GEL T         
Sbjct: 446 CLTPRLSLQLYYIPV----------------LAPEKPAAS-RQPELGELAT--------- 479

Query: 607 ISHYLGMLDPWYERNVLGLMHLPPEVLCQ--QSLKAEAQALEGSPTQLPILADMLLYYCR 664
              +LG +DPWY+ NV          LC     L     +L+ S T  P + D++ YY R
Sbjct: 480 ---FLGRVDPWYQSNV--------NTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIR 528

Query: 665 FAARPVLLQVYQTELTF--ITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDR 722
              +P+  Q+Y  ++ F  ++ + T +IF+  +EL            G   +R G+    
Sbjct: 529 MGTQPIYFQIYTVKIFFSDLSQDPTEDIFL--IELKVKIQDSKFPKDGFSPRRRGV---A 583

Query: 723 EAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSME----------- 771
           E     L + Y K  +S R R   +    T + L        E+  S             
Sbjct: 584 EGPGAELSLCYQKALLSHRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLPAAPVTDH 643

Query: 772 -ALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSV 830
             L +N+TEVVK  N  + K F+ + T+  + + +QI   +     + LD+D+++  + V
Sbjct: 644 TCLNVNVTEVVKSSN-LAGKSFSTV-TNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDV 701

Query: 831 VRCEVSPCYKP-EKSDLSSPP-------QTPPDLPAQAAPDLCSLLCLPIMTFSG 877
           VR EV+PC +P   +  S  P       Q    + A+  P     L +PI TFSG
Sbjct: 702 VRFEVAPCPEPCSGAQKSKAPWLNLHGQQEVEAIKAKPKP-----LLMPINTFSG 751



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 60/229 (26%), Positives = 99/229 (43%), Gaps = 7/229 (3%)

Query: 13  IQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEK 72
           +Q +++  L  LS    +   + G+    WSL + V RDPG   +L+  +L++  + + +
Sbjct: 10  LQRSVQAVLRELSTQAPALQSNQGMWR--WSLHKKVERDPGKSPVLVRILLRELEKAESQ 67

Query: 73  GTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDA 132
               ++ PL  L     + T       +L  +  +   R LT P PYC++  +    +  
Sbjct: 68  DLRHVIIPL--LHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKT 125

Query: 133 ELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEF---LAVANKLSTPGHSP 189
           E+  PG  YQR+V AEQ L    +       L ++P  V A     L +  + +    +P
Sbjct: 126 EMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQAQQTP 185

Query: 190 HSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQE 238
            +    ++ HA QA  G  C    LH +LQA     LE  F     A E
Sbjct: 186 ETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALE 234


>gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]
          Length = 1113

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 52/202 (25%), Positives = 78/202 (38%), Gaps = 30/202 (14%)

Query: 309  QELLQPGILGDDEEEEEEEEEVEEDLET-------DGHCAER-DSLLSTSSLASHDSTLS 360
            +E  +   + ++EEEE EEEE EED+ T       DG+ A + D   +T + A   + + 
Sbjct: 845  EETSENEAVAEEEEEEVEEEEGEEDVFTEKASPDMDGYPALKVDKETNTETPAPSPTVVR 904

Query: 361  LASSQASGPALSRHLLTSFV---SGLSDGMDSGYV-------EDSEESSSEWPWRRGSQE 410
                +   P+    L  S +      S G  S YV        DS   S + P+ R S E
Sbjct: 905  PKDRRVGTPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVRNSLE 964

Query: 411  RRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPP 470
            RR  R             K  S +   R  R +  S D  L L+   +  S L + +S  
Sbjct: 965  RRSVR------------MKRPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEISVL 1012

Query: 471  SRAQRSRSLPQPKLGTQLPSWL 492
               +      +     +LP WL
Sbjct: 1013 KELKEQLEQAKSHGEKELPQWL 1034


>gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]
          Length = 1118

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 53/204 (25%), Positives = 79/204 (38%), Gaps = 28/204 (13%)

Query: 309  QELLQPGILGDDEEEEEEEEEVEEDLET-------DGHCAER-DSLLSTSSLASHDSTLS 360
            +E  +   + ++EEEE EEEE EED+ T       DG+ A + D   +T + A   + + 
Sbjct: 845  EETSENEAVAEEEEEEVEEEEGEEDVFTEKASPDMDGYPALKVDKETNTETPAPSPTVVR 904

Query: 361  LASSQASGPALSRHLLTSFV---SGLSDGMDSGYV-------EDSEESSSEWPWRRGSQE 410
                +   P+    L  S +      S G  S YV        DS   S + P+ R S E
Sbjct: 905  PKDRRVGTPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVRNSLE 964

Query: 411  RRGHR--RPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVS 468
            RR  R  RP              S +   R  R +  S D  L L+   +  S L + +S
Sbjct: 965  RRSVRMKRPSPP--------PQPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEIS 1016

Query: 469  PPSRAQRSRSLPQPKLGTQLPSWL 492
                 +      +     +LP WL
Sbjct: 1017 VLKELKEQLEQAKSHGEKELPQWL 1040


>gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens]
          Length = 1119

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 53/204 (25%), Positives = 79/204 (38%), Gaps = 28/204 (13%)

Query: 309  QELLQPGILGDDEEEEEEEEEVEEDLET-------DGHCAER-DSLLSTSSLASHDSTLS 360
            +E  +   + ++EEEE EEEE EED+ T       DG+ A + D   +T + A   + + 
Sbjct: 845  EETSENEAVAEEEEEEVEEEEGEEDVFTEKASPDMDGYPALKVDKETNTETPAPSPTVVR 904

Query: 361  LASSQASGPALSRHLLTSFV---SGLSDGMDSGYV-------EDSEESSSEWPWRRGSQE 410
                +   P+    L  S +      S G  S YV        DS   S + P+ R S E
Sbjct: 905  PKDRRVGTPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVRNSLE 964

Query: 411  RRGHR--RPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVS 468
            RR  R  RP              S +   R  R +  S D  L L+   +  S L + +S
Sbjct: 965  RRSVRMKRPSPP--------PQPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEIS 1016

Query: 469  PPSRAQRSRSLPQPKLGTQLPSWL 492
                 +      +     +LP WL
Sbjct: 1017 VLKELKEQLEQAKSHGEKELPQWL 1040


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 52/199 (26%), Positives = 75/199 (37%), Gaps = 42/199 (21%)

Query: 319  DDEEEEEEEEEVEEDLET--------DGHCAERDSLLSTSSLAS----HDSTLSLASSQA 366
            +D+EE+EE+E+ EE ++T        DG   E DS    S  A     +DST    SS +
Sbjct: 979  EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSS 1038

Query: 367  SGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYK 426
            S  + S    +S  S  S    S   E+ EE  +  P             P  + + +  
Sbjct: 1039 SSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALP----------SASPPPREVPV-- 1086

Query: 427  LFKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSR--AQRSRSLPQ-PK 483
                                 +  +P R AGS  +PL E  + P+R       S P  P 
Sbjct: 1087 ---------------PTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPL 1131

Query: 484  LGTQLPSWLLAPASRPQRR 502
               + P+   APA RP  R
Sbjct: 1132 RPPEPPAGPPAPAPRPDER 1150



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)

Query: 307  KEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASH 355
            K Q+L Q    G++E EEE EEE EE  ++    ++ +  L   SL SH
Sbjct: 1350 KPQQLQQQREEGEEEGEEEGEEEEEESSDSSS-SSDGEGALRRRSLRSH 1397


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 39/147 (26%), Positives = 64/147 (43%), Gaps = 13/147 (8%)

Query: 231  TETAEAQELASGIGDAAEARRWLRTKLQAVGEKAGFPGVLDTAKPG-----KLHTIPIPV 285
            ++T +      G G +       ++K  +  + AG  G  +T+  G     K+ + P P 
Sbjct: 921  SKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPK 980

Query: 286  ARCYTYSWSQDSFDILQEI------LLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGH 339
            A     + + DS  +           L E+   + G+ G  EEEEEEEEE EE+ E +  
Sbjct: 981  AAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQ 1040

Query: 340  CAERDSLLSTSSLASHDSTLSLASSQA 366
              +  +  +TS+ A+  ST   A S A
Sbjct: 1041 --QPATTTATSTAAAAPSTAPSAGSTA 1065



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 16/38 (42%), Positives = 24/38 (63%)

Query: 319 DDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHD 356
           ++EEEEEEEEE EED E +   ++  S +S +    +D
Sbjct: 269 EEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYD 306



 Score = 30.8 bits (68), Expect = 5.8
 Identities = 16/42 (38%), Positives = 25/42 (59%)

Query: 319 DDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLS 360
           ++EEEEEEEEE E++ E +G       +  T +    D++LS
Sbjct: 270 EEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLS 311


>gi|23397642 GREB1 protein isoform a [Homo sapiens]
          Length = 1949

 Score = 37.7 bits (86), Expect = 0.047
 Identities = 21/55 (38%), Positives = 30/55 (54%)

Query: 317  LGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPAL 371
            L  D E+    +  +E+L T+G  +E+ S +      SHDS  S  SS+ASG AL
Sbjct: 1087 LESDAEKLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSAL 1141


>gi|23065526 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score = 37.4 bits (85), Expect = 0.062
 Identities = 56/217 (25%), Positives = 85/217 (39%), Gaps = 27/217 (12%)

Query: 440 SRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQ--PKLGTQLPSWLLAPAS 497
           SR   G SD++    ++G L +  D+  + P R + SR L    P    + P+       
Sbjct: 348 SRRYSGDSDSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPASPRRPPALRSQSRD 407

Query: 498 RPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFF 557
           R  R RP   G    + + L V            AR   +  R E    L+ R    Q  
Sbjct: 408 RLDRGRP--RGAPGGRGAQLSVP---------SPARRARSQSREEQAVLLVRRDRDGQHS 456

Query: 558 YVPVKRSHGTSPGACPP-PRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDP 616
           +VP  R  G S  + P  PR+++P+ P  S   +   ELGTTP       +      LDP
Sbjct: 457 WVPRGRGSGGSGRSTPQTPRARSPAAPRLSRVSSPSPELGTTPASIFRTPL-----QLDP 511

Query: 617 WYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLP 653
             E+ +   +        ++   A A+ALE   +  P
Sbjct: 512 QQEQQLFRRL--------EEEFLANARALEAVASVTP 540


>gi|19923777 growth arrest-specific 2 like 1 isoform a [Homo
           sapiens]
          Length = 681

 Score = 37.4 bits (85), Expect = 0.062
 Identities = 56/217 (25%), Positives = 85/217 (39%), Gaps = 27/217 (12%)

Query: 440 SRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQ--PKLGTQLPSWLLAPAS 497
           SR   G SD++    ++G L +  D+  + P R + SR L    P    + P+       
Sbjct: 348 SRRYSGDSDSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPASPRRPPALRSQSRD 407

Query: 498 RPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFF 557
           R  R RP   G    + + L V            AR   +  R E    L+ R    Q  
Sbjct: 408 RLDRGRP--RGAPGGRGAQLSVP---------SPARRARSQSREEQAVLLVRRDRDGQHS 456

Query: 558 YVPVKRSHGTSPGACPP-PRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDP 616
           +VP  R  G S  + P  PR+++P+ P  S   +   ELGTTP       +      LDP
Sbjct: 457 WVPRGRGSGGSGRSTPQTPRARSPAAPRLSRVSSPSPELGTTPASIFRTPL-----QLDP 511

Query: 617 WYERNVLGLMHLPPEVLCQQSLKAEAQALEGSPTQLP 653
             E+ +   +        ++   A A+ALE   +  P
Sbjct: 512 QQEQQLFRRL--------EEEFLANARALEAVASVTP 540


>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
          Length = 517

 Score = 37.4 bits (85), Expect = 0.062
 Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 19/124 (15%)

Query: 313 QPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSL---ASSQASGP 369
           Q G   D+EE++EEEE+           +  +SL+ +S  +S D T SL   A+S +SG 
Sbjct: 92  QAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGD 151

Query: 370 ALSRHLL----------------TSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRG 413
              +  L                +S  S +S G D GY      SS+    RRGS E   
Sbjct: 152 GDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSS 211

Query: 414 HRRP 417
              P
Sbjct: 212 DGEP 215


>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
          Length = 503

 Score = 37.4 bits (85), Expect = 0.062
 Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 19/124 (15%)

Query: 313 QPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSL---ASSQASGP 369
           Q G   D+EE++EEEE+           +  +SL+ +S  +S D T SL   A+S +SG 
Sbjct: 92  QAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGD 151

Query: 370 ALSRHLL----------------TSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRG 413
              +  L                +S  S +S G D GY      SS+    RRGS E   
Sbjct: 152 GDGKEGLEEPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSS 211

Query: 414 HRRP 417
              P
Sbjct: 212 DGEP 215


>gi|54859722 nucleoporin 160kDa [Homo sapiens]
          Length = 1436

 Score = 37.0 bits (84), Expect = 0.081
 Identities = 17/59 (28%), Positives = 32/59 (54%)

Query: 760 CRKQEELDSSMEALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVC 818
           C K +E+ + + A+ L + E+      + +KGFN      I+++  Q+ GSN+  + VC
Sbjct: 659 CSKLQEIRNPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVC 717


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 37.0 bits (84), Expect = 0.081
 Identities = 17/28 (60%), Positives = 22/28 (78%)

Query: 308 EQELLQPGILGDDEEEEEEEEEVEEDLE 335
           E E+L P +  ++EEEEEEEEEVEE+ E
Sbjct: 5   EGEVLLPALYEEEEEEEEEEEEVEEEEE 32



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 319  DDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGP 369
            ++ EE++EEEE EED E      E D   S+      ++ L L+ S+ S P
Sbjct: 1079 EENEEDKEEEEKEEDSE-----EEEDDADSSLESPEENNPLRLSESKKSSP 1124


>gi|168823443 RAD54-like 2 [Homo sapiens]
          Length = 1467

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 58/217 (26%), Positives = 87/217 (40%), Gaps = 27/217 (12%)

Query: 312 LQPGILGDDEEEEEEEEEVE-EDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPA 370
           L P +  +D EEEEEEEEV  E+ + D    + + LL   SL   +       +Q     
Sbjct: 13  LDPDVELEDAEEEEEEEEVAVEECDRD----DEEDLLDDPSL---EGMCGTEHAQLGEDG 65

Query: 371 LSRHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIR---IYKL 427
                 TS  S  S+  +       +  +SE P ++ +Q+    RR  +K +R   +  +
Sbjct: 66  QQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPV 125

Query: 428 FKSTSQLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQ 487
            K+  Q  L R  R  +   D A P+        PL+    P   A R+        G Q
Sbjct: 126 TKAAQQEELERRKRLEQQRKDYAAPIPTV-----PLE--FLPEEIALRASD------GPQ 172

Query: 488 LPSWLLAPASRPQRRRPFLSGDEDPKASTLRVVVFGS 524
           LP  +LA   +        SG ED K+S   V+   S
Sbjct: 173 LPPRVLA---QEVICLDSSSGSEDEKSSRDEVIELSS 206


>gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]
          Length = 540

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 21/89 (23%)

Query: 316 ILGDDEEEEEEEEEVEEDL---ETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALS 372
           +L D EEEEEEEEE EED    E +G   ER+ L        H                 
Sbjct: 458 VLVDSEEEEEEEEEEEEDAAVGEQEG-AREREELPKEIPKQDH----------------- 499

Query: 373 RHLLTSFVSGLSDGMDSGYVEDSEESSSE 401
            H +T+ V+G  + M +G+ +  ++SS E
Sbjct: 500 IHRVTALVNGNIEQMGNGFQDLQDDSSEE 528


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 9/116 (7%)

Query: 259  AVGEKAGFPGVLDTAKPGKLHTIPIPVARCYTYSWSQDSFDILQEILLKEQELLQPGILG 318
            A+G+ AG PG  D A PG         A     S   +     +E+ L E+E        
Sbjct: 1642 ALGD-AGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEE----EELELPEEEAEDDEDED 1696

Query: 319  DDEE---EEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTL-SLASSQASGPA 370
            DDE+   E+++E++ +EDL TD   +  ++    +   +    L +LA+  A GPA
Sbjct: 1697 DDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAEAAGAGARTPALAALAALGAPGPA 1752


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 54/196 (27%), Positives = 75/196 (38%), Gaps = 33/196 (16%)

Query: 319 DDEEEEEEEEEVEEDL---ETDGHCAERDSLLSTSSL---ASHDSTLSLASSQASGPALS 372
           +D+E E EEE+ +EDL   + D    E D+ LS  +L      DS    ++ ++   + S
Sbjct: 149 EDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRS 208

Query: 373 RHLLTSFVSGLSDGMDSGYVEDSEESSSEWPWRRGSQERRGHRRPGQKFIRIYKLFKSTS 432
            H  +S  S       S     S  SSS     R S   R   R  +             
Sbjct: 209 SHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKS------------ 256

Query: 433 QLVLRRDSRSLEGSSDTALPLRRAGSLCSPLDEPVSPPSRAQRSRSLPQPKLGTQLPSWL 492
               R  SRS  GSS    P +R+ S  S   E     SR++ S S  + K  T+  S  
Sbjct: 257 ----RSSSRSHRGSSS---PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRS-- 307

Query: 493 LAPASRPQRRRPFLSG 508
                 P+RR    SG
Sbjct: 308 ------PERRHRSSSG 317


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 34/95 (35%), Positives = 43/95 (45%), Gaps = 6/95 (6%)

Query: 308  EQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQAS 367
            E+E L       +EEEE EEEE EED + D    +RD     S     D+ LS AS +  
Sbjct: 1037 EKESLSEEQESTEEEEEAEEEEEEED-DDDDDSDDRDE----SENDDEDTALSEASEKDE 1091

Query: 368  GPALSRHLLTSFVSGLSDGMDSGYVEDSE-ESSSE 401
            G +     ++   S       S   E SE ESSSE
Sbjct: 1092 GDSDEEETVSIVTSKAEATSSSESSESSEFESSSE 1126



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 6/101 (5%)

Query: 302  QEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSL-----ASHD 356
            +E L +EQE  +     ++EEEEE++++ + D   +    + D+ LS +S      +  +
Sbjct: 1038 KESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEE 1097

Query: 357  STLSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEE 397
             T+S+ +S+A   + S    +S     S+   S   ED EE
Sbjct: 1098 ETVSIVTSKAEATSSSESSESSEFESSSESSPSS-SEDEEE 1137


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 56/223 (25%), Positives = 81/223 (36%), Gaps = 51/223 (22%)

Query: 398 SSSEWPWRRG----SQERRGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTA--- 450
           S S  P RRG    S ER+   R  Q+  R     +     +  R SRSL      A   
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 451 LPLRRA--GSLCSPLDEPVSPPSRAQ-----------------RSRSLPQPKLGTQLPSW 491
           L LRR+  GS   P  +  +PP R++                 RS S P PK  ++ PS 
Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS- 831

Query: 492 LLAPASRPQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRF 551
                     R+   S    PK  +      G+    G +    +N + +   R      
Sbjct: 832 ----------RQSHSSSSPHPKVKS------GTPPRQGSITSPQANEQSVTPQRRSC--- 872

Query: 552 FKLQFFYVPVKRSHGTSPGAC---PPPRSQTPSPPTDSPRHAS 591
              +    P  +S   S  +C    PPR ++ +PP  SP  +S
Sbjct: 873 --FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSS 913



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 53/186 (28%), Positives = 72/186 (38%), Gaps = 40/186 (21%)

Query: 429  KSTSQLVLRRDSRS---LEGSSDTALPLRRAGSLCSP--LDEPVSPPSRAQRSRSLPQPK 483
            K+ ++  LR+ SRS    E  S + L  RR+ S  SP   D+P + P     S S P+PK
Sbjct: 1566 KAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPK 1625

Query: 484  LGTQLPSWLLAPASRPQRRRPFLSG-----------------DEDPKASTLRVVVFGSDR 526
                      AP + P+R R   S                  +  PK+ T R     S  
Sbjct: 1626 AP--------APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSP- 1676

Query: 527  ISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDS 586
               K        RR   + P LTR  +L       +RS   S  + P  RS+TP     S
Sbjct: 1677 -EPKTKSRTPPRRRSSRSSPELTRKARLS------RRSRSAS--SSPETRSRTPPRHRRS 1727

Query: 587  PRHASP 592
            P  +SP
Sbjct: 1728 PSVSSP 1733



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 11/87 (12%)

Query: 438 RDSRSLEGSSDTALPLRRAGSLCSPL------DEPVSPPSRAQRSRSLPQPKLGTQLPSW 491
           R S   E  + T L   R G    PL       EPV+PPS A  +R    PK   +LP  
Sbjct: 356 RSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQS 415

Query: 492 LLAPASRPQRR-----RPFLSGDEDPK 513
             + +S P  +     R   S  E PK
Sbjct: 416 SSSESSPPSPQPTKVSRHASSSPESPK 442



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 54/214 (25%), Positives = 87/214 (40%), Gaps = 36/214 (16%)

Query: 398 SSSEWPWRRGSQER-RGHRRPGQKFIRIYKLFKSTSQLVLRRDSRSLEGSSDTALPLRRA 456
           S S  P RR  + R R   R G+   R  +  +S S+ ++RR      G S +  P RR 
Sbjct: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR------GRSHSRTPQRRG 722

Query: 457 GSLCSPLDEPVSPPS-RAQRSRSLPQPK---LGTQLPSWLLAPASRPQRRRPFLSGDEDP 512
            S  S   +  S  S R  RS S P+ K   + ++    L +P S+ + R          
Sbjct: 723 RSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRL--------- 773

Query: 513 KASTLRVVVFGSDRISGKVARAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSHGTSPGAC 572
              +LR  + GS     + ++      R  +++P             P +RS  +S    
Sbjct: 774 ---SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS-------RTPPRRSRSSSS--- 820

Query: 573 PPPRSQTPSPPTDSPRHASPG---ELGTTPWEES 603
           PPP+ ++ +P   S   +SP    + GT P + S
Sbjct: 821 PPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS 854


>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
            sapiens]
          Length = 1108

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%)

Query: 295  QDSFDILQEILLKEQELLQP-GILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLA 353
            ++  D   E L +E+E  +P G   ++EEEEE EEE  E+ E +G  A+ + L+      
Sbjct: 1024 EEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAE 1083

Query: 354  SHDSTLSLASSQAS 367
            S  S+L     ++S
Sbjct: 1084 SQASSLGQKVGESS 1097


>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
            sapiens]
          Length = 1124

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 1/74 (1%)

Query: 295  QDSFDILQEILLKEQELLQP-GILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLA 353
            ++  D   E L +E+E  +P G   ++EEEEE EEE  E+ E +G  A+ + L+      
Sbjct: 1040 EEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAE 1099

Query: 354  SHDSTLSLASSQAS 367
            S  S+L     ++S
Sbjct: 1100 SQASSLGQKVGESS 1113


>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
          Length = 668

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 31/103 (30%), Positives = 43/103 (41%), Gaps = 18/103 (17%)

Query: 411 RRGHRRPGQKFIRIYKLFKSTSQLVLRRD---------SRSLEGSSDTALPLRRAGSLCS 461
           R G RRP +K + +  +    S +  RR          SRS+ G+S        +G   S
Sbjct: 372 RHGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQRSRSISGAS--------SGLSTS 423

Query: 462 PLDEPVSPPSRAQRSRSLPQPKLGTQLPSWLLAPASRPQRRRP 504
           PL  P   P  + R   LP PK GT + +   +PA  P    P
Sbjct: 424 PLSSPRVTPHPSPRGSPLPTPK-GTPVHTPKESPAGTPNPTPP 465


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 12/103 (11%)

Query: 299 DILQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDST 358
           D + E   K++    P ++  +EEEEEEEEE E + E      E+DS     +  S D  
Sbjct: 168 DCVSEKTKKDEAFYHPRLIIYEEEEEEEEEEEEVENE------EQDS----QNEGSTDEK 217

Query: 359 LSLASSQASGPALSRHLLTSFVSGLSDGMDSGYVEDSEESSSE 401
            S ASSQ   P+  +    S  S           +DS +SS E
Sbjct: 218 SSPASSQEGSPSGDQQF--SPKSNTEKSKGELMFDDSSDSSPE 258


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 20/44 (45%), Positives = 25/44 (56%)

Query: 294 SQDSFDILQEILLKEQELLQPGILGDDEEEEEEEEEVEEDLETD 337
           SQD      E    E+   Q GIL  +EE+EEEEEE EE+ E +
Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDE 275



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 13/19 (68%), Positives = 16/19 (84%)

Query: 319 DDEEEEEEEEEVEEDLETD 337
           +DEEEEEEEEE EE+ E +
Sbjct: 273 EDEEEEEEEEEEEEEEEEE 291



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 13/19 (68%), Positives = 16/19 (84%)

Query: 319 DDEEEEEEEEEVEEDLETD 337
           D+EEEEEEEEE EE+ E +
Sbjct: 274 DEEEEEEEEEEEEEEEEEE 292


>gi|122937247 unc-13 homolog A [Homo sapiens]
          Length = 1791

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 22/56 (39%), Positives = 35/56 (62%), Gaps = 10/56 (17%)

Query: 293 WSQDSFDILQEI--LLKEQELLQPGILGDDEEEEEEEEEVEEDLETDGHCAERDSL 346
           W QD  ++ +++   L+E+EL +     D+EE EEEEEEV +DL   G  A+R+ +
Sbjct: 405 WDQDEEELEEDLEDFLEEEELPE-----DEEELEEEEEEVPDDL---GSYAQREDV 452


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 18/40 (45%), Positives = 26/40 (65%), Gaps = 1/40 (2%)

Query: 319 DDEEEEEEEEEVEEDLETDGH-CAERDSLLSTSSLASHDS 357
           DDEE+EEEEEE EED + D    A++++L     ++ H S
Sbjct: 149 DDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQS 188


>gi|38373682 pleckstrin homology domain containing family G member 5
           isoform a [Homo sapiens]
          Length = 1006

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 319 DDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTS 378
           D++EEEEEEEE EE+ E  G  A     +   S  S DS     +S  S   L+  ++  
Sbjct: 709 DEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDS--QHCASDGSTETLAMVVVEP 766

Query: 379 FVSGLSDGMDSG-YVEDSEESS 399
             +  S   DSG +   S+E+S
Sbjct: 767 GDTLSSPEFDSGPFSSQSDETS 788


>gi|111154084 pleckstrin homology domain containing family G member
           5 isoform b [Homo sapiens]
          Length = 1083

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 319 DDEEEEEEEEEVEEDLETDGHCAERDSLLSTSSLASHDSTLSLASSQASGPALSRHLLTS 378
           D++EEEEEEEE EE+ E  G  A     +   S  S DS     +S  S   L+  ++  
Sbjct: 786 DEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDS--QHCASDGSTETLAMVVVEP 843

Query: 379 FVSGLSDGMDSG-YVEDSEESS 399
             +  S   DSG +   S+E+S
Sbjct: 844 GDTLSSPEFDSGPFSSQSDETS 865


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,681,649
Number of Sequences: 37866
Number of extensions: 1904127
Number of successful extensions: 20007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 163
Number of HSP's that attempted gapping in prelim test: 16398
Number of HSP's gapped (non-prelim): 2261
length of query: 880
length of database: 18,247,518
effective HSP length: 111
effective length of query: 769
effective length of database: 14,044,392
effective search space: 10800137448
effective search space used: 10800137448
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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