Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 21687151
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
(341 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 688 0.0
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 140 2e-33
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 127 1e-29
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 127 1e-29
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 126 2e-29
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 125 7e-29
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 125 7e-29
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 125 7e-29
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 125 7e-29
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 125 7e-29
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 125 7e-29
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 120 2e-27
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 118 7e-27
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 105 8e-23
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 105 8e-23
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 105 8e-23
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 104 1e-22
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 104 1e-22
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 102 4e-22
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 102 5e-22
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 96 4e-20
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 91 1e-18
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 91 1e-18
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 90 3e-18
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 89 7e-18
gi|13259541 uncoupling protein 2 [Homo sapiens] 87 2e-17
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 86 4e-17
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 86 4e-17
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 86 5e-17
gi|13899342 solute carrier [Homo sapiens] 86 5e-17
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 688 bits (1776), Expect = 0.0
Identities = 341/341 (100%), Positives = 341/341 (100%)
Query: 1 MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVW 60
MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVW
Sbjct: 1 MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVW 60
Query: 61 RAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVS 120
RAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVS
Sbjct: 61 RAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVS 120
Query: 121 TIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAG 180
TIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAG
Sbjct: 121 TIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAG 180
Query: 181 SLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSG 240
SLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSG
Sbjct: 181 SLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSG 240
Query: 241 GVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGY 300
GVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGY
Sbjct: 241 GVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGY 300
Query: 301 ILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKLKPKKPTL 341
ILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKLKPKKPTL
Sbjct: 301 ILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKLKPKKPTL 341
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 140 bits (352), Expect = 2e-33
Identities = 90/295 (30%), Positives = 144/295 (48%), Gaps = 27/295 (9%)
Query: 17 LCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVAC 76
L G+AG + + APL+ VL Q G ++ V + EG L+KGN
Sbjct: 41 LAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMM 100
Query: 77 LRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIM 136
+R+FP A+Q A+ + L T LG +MAGS+AGM + I TYP D+++ RL
Sbjct: 101 IRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAF 160
Query: 137 QNILEPSYRGLLHAFSTIYQQE-GFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW--- 192
Q E SY G++HAF TIY +E GF YRG+ T++G P++ S + L+ +
Sbjct: 161 QVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSH 220
Query: 193 --------NGPRDQFSLPQNFANVC---LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGG 241
+ + + N+ +A A+ QT+S+PF+ +R+MQ G
Sbjct: 221 APTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQL--------GT 272
Query: 242 VDVHFSGAV---DCFRQIVKAQGV-LGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
V F + D + + G+ GL+ GL+ N ++ +P + F+T+E K+
Sbjct: 273 VLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327
Score = 58.9 bits (141), Expect = 6e-09
Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 9/188 (4%)
Query: 109 SIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVS 168
S +AG +AG + P D +K L N + G+ A + Q+EGFL LY+G
Sbjct: 39 SFLAGGIAGCCAKTTVAPLDRVKVLLQAHN-HHYKHLGVFSALRAVPQKEGFLGLYKGNG 97
Query: 169 LTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRK 228
++ P+ A + + + + + +A ++P + V+ +
Sbjct: 98 AMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVR 157
Query: 229 MQAQSPYLPHSGGVDVHFSGAVDCFRQI-VKAQGVLGLWNGLTANLLKIVPYFGIMFSTF 287
+ Q HS ++G + F+ I K G G + GL +L + PY G+ F TF
Sbjct: 158 LAFQVKG-EHS------YTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTF 210
Query: 288 EFCKRICL 295
K + L
Sbjct: 211 GTLKSVGL 218
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 8/98 (8%)
Query: 196 RDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQ 255
R F ++F +A +T P + VK +QA + + H G R
Sbjct: 31 RRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLG--------VFSALRA 82
Query: 256 IVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRI 293
+ + +G LGL+ G A +++I PY I F FE K +
Sbjct: 83 VPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTL 120
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/202 (20%), Positives = 83/202 (41%), Gaps = 27/202 (13%)
Query: 15 RLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAE--GLRALWKGN 72
RL+ +AG ++ T PL++ V V H+ + A+ G ++G
Sbjct: 133 RLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGL 192
Query: 73 AVACLRLFPCSAVQLAAYRKFVVLFTDDLGH-----------------ISQWSSIMAGSL 115
L + P + V ++ F L + L H + +++ G +
Sbjct: 193 MPTILGMAPYAGV---SFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGV 249
Query: 116 AGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFST---IYQQEGFL-ALYRGVSLTV 171
AG ++ ++YP D+ + R+ + +L P + L T +Y G LYRG+SL
Sbjct: 250 AGAIAQTISYPFDVTRRRMQLGTVL-PEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNY 308
Query: 172 VGALPFSAGSLLVYMNLEKIWN 193
+ +P A + Y +++ ++
Sbjct: 309 IRCIPSQAVAFTTYELMKQFFH 330
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 127 bits (319), Expect = 1e-29
Identities = 80/283 (28%), Positives = 145/283 (51%), Gaps = 12/283 (4%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
++LL G+AG +S + TAPL+ ++ QV + + ++ + G+R+LW+GN
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 255
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+++ P +AV+ AY ++ L T++ I + ++GS+AG + YP +++KTR
Sbjct: 256 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 315
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
L + Y G+ I + EG A Y+G ++G +P++ L VY L+ W
Sbjct: 316 LAVGK--TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 373
Query: 193 -NGPRDQFSLPQNFANVC--LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGA 249
N +D + C L++ Q S+P V+ +MQAQ+ G ++ G
Sbjct: 374 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML---EGSPQLNMVG- 429
Query: 250 VDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
FR+I+ +G+ GL+ G+T N +K++P GI + +E K+
Sbjct: 430 --LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 470
Score = 80.5 bits (197), Expect = 2e-15
Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 97 FTDDLGHISQW-SSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIY 155
FT+D QW ++AG +AG VS T P D +K + + + + F +
Sbjct: 184 FTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHG-SKSDKMNIFGGFRQMV 242
Query: 156 QQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVT 215
++ G +L+RG V+ P +A Y +K+ + + F + +A A
Sbjct: 243 KEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATA 302
Query: 216 QTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
QT +P E +K ++ G +SG DC ++I+K +G+ + G NLL
Sbjct: 303 QTFIYPMEVMKTRLAV---------GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLG 353
Query: 276 IVPYFGIMFSTFEFCK 291
I+PY GI + +E K
Sbjct: 354 IIPYAGIDLAVYELLK 369
Score = 42.0 bits (97), Expect = 8e-04
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 8/84 (9%)
Query: 210 LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGL 269
+A AV++T + P + +K MQ S +++ F G FRQ+VK G+ LW G
Sbjct: 203 IAGAVSRTSTAPLDRLKIMMQVHGS---KSDKMNI-FGG----FRQMVKEGGIRSLWRGN 254
Query: 270 TANLLKIVPYFGIMFSTFEFCKRI 293
N++KI P + F +E K++
Sbjct: 255 GTNVIKIAPETAVKFWAYEQYKKL 278
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 127 bits (319), Expect = 1e-29
Identities = 80/283 (28%), Positives = 145/283 (51%), Gaps = 12/283 (4%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
++LL G+AG +S + TAPL+ ++ QV + + ++ + G+R+LW+GN
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 236
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+++ P +AV+ AY ++ L T++ I + ++GS+AG + YP +++KTR
Sbjct: 237 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 296
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
L + Y G+ I + EG A Y+G ++G +P++ L VY L+ W
Sbjct: 297 LAVGK--TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
Query: 193 -NGPRDQFSLPQNFANVC--LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGA 249
N +D + C L++ Q S+P V+ +MQAQ+ G ++ G
Sbjct: 355 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML---EGSPQLNMVG- 410
Query: 250 VDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
FR+I+ +G+ GL+ G+T N +K++P GI + +E K+
Sbjct: 411 --LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
Score = 80.5 bits (197), Expect = 2e-15
Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 97 FTDDLGHISQW-SSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIY 155
FT+D QW ++AG +AG VS T P D +K + + + + F +
Sbjct: 165 FTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHG-SKSDKMNIFGGFRQMV 223
Query: 156 QQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVT 215
++ G +L+RG V+ P +A Y +K+ + + F + +A A
Sbjct: 224 KEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATA 283
Query: 216 QTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
QT +P E +K ++ G +SG DC ++I+K +G+ + G NLL
Sbjct: 284 QTFIYPMEVMKTRLAV---------GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLG 334
Query: 276 IVPYFGIMFSTFEFCK 291
I+PY GI + +E K
Sbjct: 335 IIPYAGIDLAVYELLK 350
Score = 42.0 bits (97), Expect = 8e-04
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 8/84 (9%)
Query: 210 LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGL 269
+A AV++T + P + +K MQ S +++ F G FRQ+VK G+ LW G
Sbjct: 184 IAGAVSRTSTAPLDRLKIMMQVHGS---KSDKMNI-FGG----FRQMVKEGGIRSLWRGN 235
Query: 270 TANLLKIVPYFGIMFSTFEFCKRI 293
N++KI P + F +E K++
Sbjct: 236 GTNVIKIAPETAVKFWAYEQYKKL 259
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 126 bits (317), Expect = 2e-29
Identities = 81/281 (28%), Positives = 140/281 (49%), Gaps = 18/281 (6%)
Query: 16 LLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVA 75
LL LAG L+ + APL+ ++ QV R A+ + + + EG +LW+GN+
Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
Query: 76 CLRLFPCSAVQLAAYRKFVVLFTDDLGH----ISQWSSIMAGSLAGMVSTIVTYPTDLIK 131
+R+ P +A+Q +A+ ++ + G + W + AG+LAG + +TYP DL++
Sbjct: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
Query: 132 TRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKI 191
R+ + + Y + H F I ++EG LY G TV+G +P++ S Y L+ +
Sbjct: 157 ARMAVTP--KEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSL 214
Query: 192 ---WNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSG 248
++G R + + C A + Q+ S+P + V+R+MQ +G +
Sbjct: 215 HREYSGRRQPYPFERMIFGAC-AGLIGQSASYPLDVVRRRMQT-------AGVTGYPRAS 266
Query: 249 AVDCFRQIVKAQG-VLGLWNGLTANLLKIVPYFGIMFSTFE 288
R IV+ +G V GL+ GL+ N +K GI F+TF+
Sbjct: 267 IARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
Score = 65.9 bits (159), Expect = 5e-11
Identities = 53/199 (26%), Positives = 95/199 (47%), Gaps = 22/199 (11%)
Query: 103 HISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQ---QEG 159
H SS++ G+LAG ++ P D +T++I Q + AF +Y EG
Sbjct: 30 HRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQ--VSSKRFSAKEAFRVLYYTYLNEG 85
Query: 160 FLALYRGVSLTVVGALPFSAGSLLVYMNLEKI---WNGPRDQF--SLPQNFANVCLAAAV 214
FL+L+RG S T+V +P++A + ++I + G R + P+ FA LA
Sbjct: 86 FLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGA-LAGTT 144
Query: 215 TQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLL 274
+L++P + V+ +M + +S F +I + +G+ L++G +L
Sbjct: 145 AASLTYPLDLVRARMAVTPKEM---------YSNIFHVFIRISREEGLKTLYHGFMPTVL 195
Query: 275 KIVPYFGIMFSTFEFCKRI 293
++PY G+ F T+E K +
Sbjct: 196 GVIPYAGLSFFTYETLKSL 214
Score = 55.5 bits (132), Expect = 7e-08
Identities = 47/181 (25%), Positives = 82/181 (45%), Gaps = 7/181 (3%)
Query: 15 RLLCAGLAGTLSLSLTAPLELATVLAQVGVV-RGHARGPWATGHRVWRAEGLRALWKGNA 73
RL LAGT + SLT PL+L V A++ V + + R+ R EGL+ L+ G
Sbjct: 134 RLFAGALAGTTAASLTYPLDL--VRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFM 191
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQW--SSIMAGSLAGMVSTIVTYPTDLIK 131
L + P + + Y L + G + ++ G+ AG++ +YP D+++
Sbjct: 192 PTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVR 251
Query: 132 TRLIMQNILEPSYRGLLHAFSTIYQQEGFL-ALYRGVSLTVVGALPFSAGSLLVYMNLEK 190
R+ + + TI ++EG + LY+G+S+ V P + G +L +
Sbjct: 252 RRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKG-PIAVGISFTTFDLMQ 310
Query: 191 I 191
I
Sbjct: 311 I 311
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 14/101 (13%)
Query: 196 RDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQ 255
RD + + LA A+ +T P + K Q S FS A + FR
Sbjct: 28 RDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSK----------RFS-AKEAFRV 76
Query: 256 IVKA---QGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRI 293
+ +G L LW G +A ++++VPY I FS E KRI
Sbjct: 77 LYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRI 117
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 125 bits (313), Expect = 7e-29
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 308 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
Query: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 366 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 419
Query: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 420 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 84.3 bits (207), Expect = 1e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 187 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 245
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 246 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 306 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 356
Query: 287 FEFCKRICL 295
+E K L
Sbjct: 357 YETLKNAWL 365
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 125 bits (313), Expect = 7e-29
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 281
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 282 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 341
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 342 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 399
Query: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 400 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 453
Query: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 454 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 84.3 bits (207), Expect = 1e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 279
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 280 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 339
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 340 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 390
Query: 287 FEFCKRICL 295
+E K L
Sbjct: 391 YETLKNAWL 399
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 125 bits (313), Expect = 7e-29
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 208 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 267
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 268 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 327
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 328 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 385
Query: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 386 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 439
Query: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 440 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 84.3 bits (207), Expect = 1e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 207 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 265
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 266 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 325
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 326 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 376
Query: 287 FEFCKRICL 295
+E K L
Sbjct: 377 YETLKNAWL 385
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 125 bits (313), Expect = 7e-29
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 188 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 247
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 248 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 307
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 308 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 365
Query: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 366 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 419
Query: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 420 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 84.3 bits (207), Expect = 1e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 187 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 245
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 246 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 305
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 306 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 356
Query: 287 FEFCKRICL 295
+E K L
Sbjct: 357 YETLKNAWL 365
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 125 bits (313), Expect = 7e-29
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 85 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 144
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 145 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 204
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 205 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 262
Query: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 263 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 316
Query: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 317 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 84.3 bits (207), Expect = 1e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 84 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 142
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 143 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 202
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 203 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 253
Query: 287 FEFCKRICL 295
+E K L
Sbjct: 254 YETLKNAWL 262
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 125 bits (313), Expect = 7e-29
Identities = 84/285 (29%), Positives = 139/285 (48%), Gaps = 18/285 (6%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
+ L+ G AG +S + TAPL+ VL QV R + G ++ R G R+LW+GN
Sbjct: 222 RHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNG 281
Query: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
+ L++ P SA++ AY + L D + ++AGSLAG ++ YP +++KTR
Sbjct: 282 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTR 341
Query: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
+ ++ Y G+L I +EG A Y+G ++G +P++ L VY L+ W
Sbjct: 342 MALRK--TGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWL 399
Query: 193 ------NGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHF 246
+ F L A +++ Q S+P V+ +MQAQ+ G +V
Sbjct: 400 QHYAVNSADPGVFVL---LACGTMSSTCGQLASYPLALVRTRMQAQASI---EGAPEVTM 453
Query: 247 SGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
S F+ I++ +G GL+ GL N +K++P I + +E K
Sbjct: 454 S---SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 84.3 bits (207), Expect = 1e-16
Identities = 52/189 (27%), Positives = 93/189 (49%), Gaps = 10/189 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W ++AG AG VS T P D +K L+ + + G++ F+ + ++ G +L+RG
Sbjct: 221 WRHLVAGGGAGAVSRTCTAPLDRLKV-LMQVHASRSNNMGIVGGFTQMIREGGARSLWRG 279
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P SA + Y ++++ ++ + + LA A+ Q+ +P E +K
Sbjct: 280 NGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLK 339
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
+M L +G +SG +DC R+I+ +GV + G N+L I+PY GI +
Sbjct: 340 TRMA-----LRKTG----QYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAV 390
Query: 287 FEFCKRICL 295
+E K L
Sbjct: 391 YETLKNAWL 399
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 120 bits (301), Expect = 2e-27
Identities = 84/292 (28%), Positives = 143/292 (48%), Gaps = 18/292 (6%)
Query: 9 RLTG--GQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLR 66
+LTG ++L+ +AG +S + TAPL+ V QV + + + G+R
Sbjct: 180 KLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIR 239
Query: 67 ALWKGNAVACLRLFPCSAVQLAAYR--KFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVT 124
+LW+GN + L++ P SA++ AY K +L + H+ + +AGSLAG + +
Sbjct: 240 SLWRGNGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQE--RFVAGSLAGATAQTII 297
Query: 125 YPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLV 184
YP +++KTRL ++ Y+GLL I ++EG A YRG V+G +P++ L V
Sbjct: 298 YPMEVLKTRLTLRR--TGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355
Query: 185 YMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQT----LSFPFETVKRKMQAQSPYLPHSG 240
Y L+ W S + ++ T S+P V+ +MQAQ+ G
Sbjct: 356 YETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASI---EG 412
Query: 241 GVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
G + G + R I+ +G+ GL+ G+ N +K++P I + +E K+
Sbjct: 413 GPQLSMLGLL---RHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQ 461
Score = 81.3 bits (199), Expect = 1e-15
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 10/191 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W ++AG++AG VS T P D +K + + + + +L ++ + G +L+RG
Sbjct: 186 WKQLVAGAVAGAVSRTGTAPLDRLKV-FMQVHASKTNRLNILGGLRSMVLEGGIRSLWRG 244
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P SA + Y +++ G ++ + + F LA A QT+ +P E +K
Sbjct: 245 NGINVLKIAPESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLK 304
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
++ L +G + G +DC R+I++ +G + G N+L I+PY GI +
Sbjct: 305 TRLT-----LRRTG----QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAV 355
Query: 287 FEFCKRICLYQ 297
+E K L Q
Sbjct: 356 YETLKNWWLQQ 366
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 118 bits (296), Expect = 7e-27
Identities = 84/280 (30%), Positives = 138/280 (49%), Gaps = 12/280 (4%)
Query: 16 LLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVA 75
LL +AG +S + TAPL+ A V QV + + + + G R+LW+GN +
Sbjct: 96 LLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGIN 155
Query: 76 CLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLI 135
L++ P A++ + + + F G ++AGSLA +S + P +++KTRL
Sbjct: 156 VLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLKTRLT 215
Query: 136 MQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGP 195
++ Y+GLL I Q+EG ALYRG ++G +P++ L VY L+ W
Sbjct: 216 LRR--TGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKS 273
Query: 196 RDQFSLPQ---NFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDC 252
P + ++V L+ Q S+P V+ +MQAQ G + G +
Sbjct: 274 GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV----EGSNPTMRGVL-- 327
Query: 253 FRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
++I+ QG LGL+ G+T LLK++P GI + +E K+
Sbjct: 328 -QRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKK 366
Score = 73.6 bits (179), Expect = 2e-13
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 10/173 (5%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
W +++G++AG VS T P D K + + + + ++ LL ++ Q+ GF +L+RG
Sbjct: 93 WKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYS-SKTNFTNLLGGLQSMVQEGGFRSLWRG 151
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVK 226
+ V+ P A V+ + + G + + LA A++QTL P E +K
Sbjct: 152 NGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQERLLAGSLAVAISQTLINPMEVLK 211
Query: 227 RKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPY 279
++ L +G + G +DC RQI++ +G L+ G N+L I+PY
Sbjct: 212 TRLT-----LRRTG----QYKGLLDCARQILQREGTRALYRGYLPNMLGIIPY 255
Score = 72.8 bits (177), Expect = 4e-13
Identities = 55/183 (30%), Positives = 92/183 (50%), Gaps = 10/183 (5%)
Query: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
+RLL LA +S +L P+E+ + G +G ++ + EG RAL++G
Sbjct: 188 ERLLAGSLAVAISQTLINPMEVLKTRLTLRRT-GQYKGLLDCARQILQREGTRALYRGYL 246
Query: 74 VACLRLFPCSAVQLAAYRK---FVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLI 130
L + P + LA Y F V D+G S S+ + +L+ + +YP L+
Sbjct: 247 PNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLV 306
Query: 131 KTRLIMQNILE---PSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMN 187
+TR+ Q+ +E P+ RG+L I Q+G+L LYRG++ T++ LP S +VY
Sbjct: 307 RTRMQAQDTVEGSNPTMRGVLQR---ILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEA 363
Query: 188 LEK 190
++K
Sbjct: 364 MKK 366
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 105 bits (261), Expect = 8e-23
Identities = 79/300 (26%), Positives = 147/300 (49%), Gaps = 20/300 (6%)
Query: 7 DGRLTGGQRLLCAG-LAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRA--- 62
DGR ++ AG ++G ++ +L +P ++ + Q+ R P A H + +A
Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
Query: 63 ----EGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSI--MAGSLA 116
EG A WKG+ A + AVQ ++ L + ++ S+ + G LA
Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLA 128
Query: 117 GMVSTIVTYPTDLIKTRLIMQNILEPS-YRGLLHAFSTIYQQEGFLALYRGVSLTVVGAL 175
++T+ +P D+++TR Q EP Y L HA T+Y+ EG Y+G++ T++
Sbjct: 129 ACMATLTVHPVDVLRTRFAAQG--EPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIF 186
Query: 176 PFSAGSLLVYMNLEKI--WNGPRDQFSLPQNFANVCL---AAAVTQTLSFPFETVKRKMQ 230
P++ Y +L+ + W P + +N N+ A +++TL++P + K+++Q
Sbjct: 187 PYAGLQFSCYSSLKHLYKWAIPAEG-KKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQ 245
Query: 231 AQS-PYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEF 289
+ + G + G +DC +Q+++ +G LG + GL+ +LLK G MF ++EF
Sbjct: 246 VGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 105 bits (261), Expect = 8e-23
Identities = 79/300 (26%), Positives = 147/300 (49%), Gaps = 20/300 (6%)
Query: 7 DGRLTGGQRLLCAG-LAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRA--- 62
DGR ++ AG ++G ++ +L +P ++ + Q+ R P A H + +A
Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
Query: 63 ----EGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSI--MAGSLA 116
EG A WKG+ A + AVQ ++ L + ++ S+ + G LA
Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLA 128
Query: 117 GMVSTIVTYPTDLIKTRLIMQNILEPS-YRGLLHAFSTIYQQEGFLALYRGVSLTVVGAL 175
++T+ +P D+++TR Q EP Y L HA T+Y+ EG Y+G++ T++
Sbjct: 129 ACMATLTVHPVDVLRTRFAAQG--EPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIF 186
Query: 176 PFSAGSLLVYMNLEKI--WNGPRDQFSLPQNFANVCL---AAAVTQTLSFPFETVKRKMQ 230
P++ Y +L+ + W P + +N N+ A +++TL++P + K+++Q
Sbjct: 187 PYAGLQFSCYSSLKHLYKWAIPAEG-KKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQ 245
Query: 231 AQS-PYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEF 289
+ + G + G +DC +Q+++ +G LG + GL+ +LLK G MF ++EF
Sbjct: 246 VGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 105 bits (261), Expect = 8e-23
Identities = 79/300 (26%), Positives = 147/300 (49%), Gaps = 20/300 (6%)
Query: 7 DGRLTGGQRLLCAG-LAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRA--- 62
DGR ++ AG ++G ++ +L +P ++ + Q+ R P A H + +A
Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
Query: 63 ----EGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSI--MAGSLA 116
EG A WKG+ A + AVQ ++ L + ++ S+ + G LA
Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLA 128
Query: 117 GMVSTIVTYPTDLIKTRLIMQNILEPS-YRGLLHAFSTIYQQEGFLALYRGVSLTVVGAL 175
++T+ +P D+++TR Q EP Y L HA T+Y+ EG Y+G++ T++
Sbjct: 129 ACMATLTVHPVDVLRTRFAAQG--EPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIF 186
Query: 176 PFSAGSLLVYMNLEKI--WNGPRDQFSLPQNFANVCL---AAAVTQTLSFPFETVKRKMQ 230
P++ Y +L+ + W P + +N N+ A +++TL++P + K+++Q
Sbjct: 187 PYAGLQFSCYSSLKHLYKWAIPAEG-KKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQ 245
Query: 231 AQS-PYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEF 289
+ + G + G +DC +Q+++ +G LG + GL+ +LLK G MF ++EF
Sbjct: 246 VGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 104 bits (259), Expect = 1e-22
Identities = 76/276 (27%), Positives = 129/276 (46%), Gaps = 25/276 (9%)
Query: 17 LCAGLAGTLSLSLTAPLELATVLAQVG------VVRGHARGPWATGHRVWRAEGLRALWK 70
L G+A +S + AP+E +L QV +G R+ + +G + W+
Sbjct: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72
Query: 71 GNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSL-----AGMVSTIVTY 125
GN +R FP A+ A K+ LF + Q+ AG+L AG S Y
Sbjct: 73 GNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVY 132
Query: 126 PTDLIKTRL---IMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSL 182
P D +TRL + + + + GL I++ +G LY+G +++V G + + A
Sbjct: 133 PLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYF 192
Query: 183 LVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQT---LSFPFETVKRKMQAQSPYLPHS 239
VY + + P++ F + +A +VT +S+PF+TV+R+M QS
Sbjct: 193 GVYDTAKGMLPDPKN----VHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQS----GR 244
Query: 240 GGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
G D+ ++G VDC+R+I K +G + G +N+L+
Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR 280
Score = 58.9 bits (141), Expect = 6e-09
Identities = 46/198 (23%), Positives = 84/198 (42%), Gaps = 17/198 (8%)
Query: 107 WSSI---MAGSLAGMVSTIVTYPTDLIKTRLIMQNI-----LEPSYRGLLHAFSTIYQQE 158
WS + +AG +A VS P + +K L +Q+ E Y+G++ I +++
Sbjct: 6 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQ 65
Query: 159 GFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFS-----LPQNFANVCLAAA 213
GFL+ +RG V+ P A + ++++ G D+ N A+ A A
Sbjct: 66 GFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGA 125
Query: 214 VTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANL 273
+ +P + + ++ A G F G DC +I K+ G+ GL+ G ++
Sbjct: 126 TSLCFVYPLDFARTRLAADVG----KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSV 181
Query: 274 LKIVPYFGIMFSTFEFCK 291
I+ Y F ++ K
Sbjct: 182 QGIIIYRAAYFGVYDTAK 199
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 199 FSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVK 258
+S ++F +AAAV++T P E VK +Q Q + + + G +DC +I K
Sbjct: 6 WSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQ--HASKQISAEKQYKGIIDCVVRIPK 63
Query: 259 AQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295
QG L W G AN+++ P + F+ + K++ L
Sbjct: 64 EQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFL 100
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 104 bits (259), Expect = 1e-22
Identities = 77/277 (27%), Positives = 131/277 (47%), Gaps = 27/277 (9%)
Query: 17 LCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGH----------RVWRAEGLR 66
L G+A +S + AP+E +L QV HA A R+ + +G+
Sbjct: 13 LAGGIAAAISKTAVAPIERVKLLLQVQ----HASKQIAADKQYKGIVDCIVRIPKEQGVL 68
Query: 67 ALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSL-----AGMVST 121
+ W+GN +R FP A+ A K+ +F + +Q+ AG+L AG S
Sbjct: 69 SFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSL 128
Query: 122 IVTYPTDLIKTRL---IMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFS 178
YP D +TRL + ++ E +RGL I + +G LY+G S++V G + +
Sbjct: 129 CFVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYR 188
Query: 179 AGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPH 238
A VY + + P++ + ++ AV +S+PF+TV+R+M QS
Sbjct: 189 AAYFGVYDTAKGMLPDPKNT-HIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQS----G 243
Query: 239 SGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
G D+ ++G VDC+R+I + +G + G +N+L+
Sbjct: 244 RKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLR 280
Score = 58.9 bits (141), Expect = 6e-09
Identities = 44/198 (22%), Positives = 85/198 (42%), Gaps = 14/198 (7%)
Query: 104 ISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNI-----LEPSYRGLLHAFSTIYQQE 158
IS +AG +A +S P + +K L +Q+ + Y+G++ I +++
Sbjct: 6 ISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQ 65
Query: 159 GFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFS-----LPQNFANVCLAAA 213
G L+ +RG V+ P A + ++I+ G D+ + N A+ A A
Sbjct: 66 GVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGA 125
Query: 214 VTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANL 273
+ +P + + ++ A G + F G DC +I K+ G+ GL+ G + ++
Sbjct: 126 TSLCFVYPLDFARTRLAADVG----KSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSV 181
Query: 274 LKIVPYFGIMFSTFEFCK 291
I+ Y F ++ K
Sbjct: 182 QGIIIYRAAYFGVYDTAK 199
Score = 52.4 bits (124), Expect = 6e-07
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Query: 200 SLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKA 259
S ++F +AAA+++T P E VK +Q Q + D + G VDC +I K
Sbjct: 7 SFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQ--HASKQIAADKQYKGIVDCIVRIPKE 64
Query: 260 QGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295
QGVL W G AN+++ P + F+ + K+I L
Sbjct: 65 QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL 100
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 102 bits (255), Expect = 4e-22
Identities = 74/283 (26%), Positives = 133/283 (46%), Gaps = 19/283 (6%)
Query: 7 DGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVG------VVRGHARGPWATGHRVW 60
D ++ + L G+A +S + AP+E +L QV +G R+
Sbjct: 3 DAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIP 62
Query: 61 RAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSL----- 115
+ +G+ + W+GN +R FP A+ A K+ +F + +Q+ AG+L
Sbjct: 63 KEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGA 122
Query: 116 AGMVSTIVTYPTDLIKTRL---IMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVV 172
AG S YP D +TRL + + E +RGL IY+ +G LY+G +++V
Sbjct: 123 AGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQ 182
Query: 173 GALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQ 232
G + + A +Y + + P++ + ++ AV S+PF+TV+R+M Q
Sbjct: 183 GIIIYRAAYFGIYDTAKGMLPDPKNT-HIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQ 241
Query: 233 SPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
S G D+ ++G +DC+R+I + +G + G +N+L+
Sbjct: 242 S----GRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR 280
Score = 57.8 bits (138), Expect = 1e-08
Identities = 46/198 (23%), Positives = 85/198 (42%), Gaps = 14/198 (7%)
Query: 104 ISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNI-----LEPSYRGLLHAFSTIYQQE 158
+S +AG +A +S P + +K L +Q+ + Y+G++ I +++
Sbjct: 6 VSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQ 65
Query: 159 GFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNG---PRDQFSL--PQNFANVCLAAA 213
G L+ +RG V+ P A + ++I+ G R QF L N A+ A A
Sbjct: 66 GVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGA 125
Query: 214 VTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANL 273
+ +P + + ++ A G + F G DC +I K+ G+ GL+ G ++
Sbjct: 126 TSLCFVYPLDFARTRLAADVG----KAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSV 181
Query: 274 LKIVPYFGIMFSTFEFCK 291
I+ Y F ++ K
Sbjct: 182 QGIIIYRAAYFGIYDTAK 199
Score = 50.4 bits (119), Expect = 2e-06
Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Query: 200 SLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKA 259
S ++F +AAA+++T P E VK +Q Q + D + G +DC +I K
Sbjct: 7 SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQ--HASKQITADKQYKGIIDCVVRIPKE 64
Query: 260 QGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295
QGVL W G AN+++ P + F+ + K+I L
Sbjct: 65 QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL 100
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 102 bits (254), Expect = 5e-22
Identities = 78/280 (27%), Positives = 128/280 (45%), Gaps = 27/280 (9%)
Query: 13 GQRLLCAGLAGTLSLSLTAPLELATVLAQVGVV------RGHARGPWATGHRVWRAEGLR 66
G+ LL G+A +S + AP+E +L QV +G R+ R +G
Sbjct: 21 GKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFF 80
Query: 67 ALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQW-----SSIMAGSLAGMVST 121
+ W+GN +R FP A+ A K+ LF + Q+ +++ +G AG S
Sbjct: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
Query: 122 IVTYPTDLIKTRL---IMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFS 178
V YP D +TRL I + E ++GL I + +G LY+G ++V G + +
Sbjct: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
Query: 179 AGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQ---TLSFPFETVKRKMQAQSPY 235
A Y ++ + P+ L F +A VT LS+PF+TV+R+M Q
Sbjct: 201 ASYFGAYDTVKGLLPKPKKTPFLVSFF----IAQVVTTCSGILSYPFDTVRRRMMMQ--- 253
Query: 236 LPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
SG + G +DCF +I + +G+ + G +N+L+
Sbjct: 254 ---SGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLR 290
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 14/192 (7%)
Query: 110 IMAGSLAGMVSTIVTYPTDLIKTRLIMQNIL-----EPSYRGLLHAFSTIYQQEGFLALY 164
++AG +A VS P + +K L +Q E Y+G++ I +++GF + +
Sbjct: 24 LLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFW 83
Query: 165 RGVSLTVVGALPFSAGSLLV---YMNLEKIWNGPRDQFS--LPQNFANVCLAAAVTQTLS 219
RG V+ P A + Y L QF N A+ A A + +
Sbjct: 84 RGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVV 143
Query: 220 FPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPY 279
+P + + ++ G + F G DC +I K+ G+ GL+ G ++ I+ Y
Sbjct: 144 YPLDFARTRLGVDIG----KGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVY 199
Query: 280 FGIMFSTFEFCK 291
F ++ K
Sbjct: 200 RASYFGAYDTVK 211
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 96.3 bits (238), Expect = 4e-20
Identities = 74/256 (28%), Positives = 118/256 (46%), Gaps = 9/256 (3%)
Query: 47 GHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQ 106
G+ +G ++ R EG+++LW G + P + + Y + L LG
Sbjct: 82 GNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENET 141
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
I+AG +A + V P +LI+T++ + SY L S ++G+++L+RG
Sbjct: 142 CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF---SYVELHRFVSKKVSEDGWISLWRG 198
Query: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQ---NFANVCLAAAVTQTLSFPFE 223
+ TV+ +PFSA Y L+K W + P NF + L+ + + PF+
Sbjct: 199 WAPTVLRDVPFSAMYWYNYEILKK-WLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFD 257
Query: 224 TVKRKMQAQS-PYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGI 282
VK + Q Q Y H + +H S + + IV G GL++GL L+KI P I
Sbjct: 258 VVKTQKQTQLWTYESHKISMPLHMSTWI-IMKNIVAKNGFSGLFSGLIPRLIKIAPACAI 316
Query: 283 MFSTFEFCKRICLYQN 298
M ST+EF K QN
Sbjct: 317 MISTYEFGKAFFQKQN 332
Score = 45.4 bits (106), Expect = 7e-05
Identities = 48/245 (19%), Positives = 93/245 (37%), Gaps = 51/245 (20%)
Query: 104 ISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEP--------------------- 142
++ ++A ++++++ P D++K RL QN P
Sbjct: 13 VTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEG 72
Query: 143 ----------SYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW 192
+++G L AF I + EG +L+ G+ T+V A+P + Y L +
Sbjct: 73 GNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
Query: 193 NGPRDQFSLPQNFANVCLAAAVTQ-----TLSFPFETVKRKMQAQSPYLPHSGGVDVHFS 247
L +N + + A + T+ P E ++ KMQ++ V++H
Sbjct: 133 RS-----KLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKK-----FSYVELH-- 180
Query: 248 GAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGYILSPLSY 307
+ V G + LW G +L+ VP+ + + +E K+ ++G
Sbjct: 181 ---RFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMI 237
Query: 308 KLTPG 312
T G
Sbjct: 238 NFTSG 242
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 90.9 bits (224), Expect = 1e-18
Identities = 70/239 (29%), Positives = 110/239 (46%), Gaps = 11/239 (4%)
Query: 58 RVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAG 117
++ R EG R LW G + P +A+ AY + ++ ++AG+LA
Sbjct: 105 KIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALAR 164
Query: 118 MVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPF 177
+ + V P +L++T+L Q++ SYR L T Q G+ +L+ G T + +PF
Sbjct: 165 LGTVTVISPLELMRTKLQAQHV---SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 221
Query: 178 SAGSLLVYMNLE--KIW-NG--PRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQ 232
SA L + N E K W NG P+DQ S+ +F ++ V L+ PF+ VK + Q
Sbjct: 222 SA---LYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVA 278
Query: 233 SPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
+ +H R+I G GL+ G ++K P IM ST+EF K
Sbjct: 279 LGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGK 337
Score = 39.7 bits (91), Expect = 0.004
Identities = 18/46 (39%), Positives = 28/46 (60%)
Query: 246 FSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
F+G +D F +IV+ +G LW+GL A L+ VP I F+ ++ K
Sbjct: 96 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 141
Score = 31.6 bits (70), Expect = 1.1
Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 13 GQRLLCAGLAGTLSLSLTAPLELATVLAQV--GVVRG------HARGPWATGHRVWRAEG 64
G + G++GT++ LT P ++ QV G + H W R+ G
Sbjct: 248 GMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESG 307
Query: 65 LRALWKGNAVACLRLFPCSAVQLAAY 90
+ L+ G ++ P A+ ++ Y
Sbjct: 308 TKGLFAGFLPRIIKAAPSCAIMISTY 333
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 90.9 bits (224), Expect = 1e-18
Identities = 70/239 (29%), Positives = 110/239 (46%), Gaps = 11/239 (4%)
Query: 58 RVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAG 117
++ R EG R LW G + P +A+ AY + ++ ++AG+LA
Sbjct: 113 KIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALAR 172
Query: 118 MVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPF 177
+ + V P +L++T+L Q++ SYR L T Q G+ +L+ G T + +PF
Sbjct: 173 LGTVTVISPLELMRTKLQAQHV---SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 229
Query: 178 SAGSLLVYMNLE--KIW-NG--PRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQ 232
SA L + N E K W NG P+DQ S+ +F ++ V L+ PF+ VK + Q
Sbjct: 230 SA---LYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVA 286
Query: 233 SPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
+ +H R+I G GL+ G ++K P IM ST+EF K
Sbjct: 287 LGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGK 345
Score = 39.7 bits (91), Expect = 0.004
Identities = 18/46 (39%), Positives = 28/46 (60%)
Query: 246 FSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCK 291
F+G +D F +IV+ +G LW+GL A L+ VP I F+ ++ K
Sbjct: 104 FTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLK 149
Score = 31.6 bits (70), Expect = 1.1
Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 8/86 (9%)
Query: 13 GQRLLCAGLAGTLSLSLTAPLELATVLAQV--GVVRG------HARGPWATGHRVWRAEG 64
G + G++GT++ LT P ++ QV G + H W R+ G
Sbjct: 256 GMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESG 315
Query: 65 LRALWKGNAVACLRLFPCSAVQLAAY 90
+ L+ G ++ P A+ ++ Y
Sbjct: 316 TKGLFAGFLPRIIKAAPSCAIMISTY 341
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 89.7 bits (221), Expect = 3e-18
Identities = 80/285 (28%), Positives = 129/285 (45%), Gaps = 15/285 (5%)
Query: 20 GLAGTLSLSLTAPLELATVLAQVGVVRGHA-------RGPWATGHRVWRAEGLRALWKGN 72
GLA + T P++L Q+ A RG R+ R EGL+AL+ G
Sbjct: 13 GLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKALYSGI 72
Query: 73 AVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKT 132
A A LR +++ Y+ LF + + +++ G L+G++S+ + PTD++K
Sbjct: 73 APAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIANPTDVLKI 132
Query: 133 RLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEK-- 190
R+ Q+ G++ F IYQQEG L++GVSLT A L VY +K
Sbjct: 133 RMQAQS--NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHL 190
Query: 191 IWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAV 250
I +G ++ +F + S P + V+ +M Q G ++G +
Sbjct: 191 ILSGLMGD-TVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVL---RDGRCSGYTGTL 246
Query: 251 DCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295
DC Q K +G L+ G N L++ P+ I F T+E K++ L
Sbjct: 247 DCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKKLDL 291
Score = 83.2 bits (204), Expect = 3e-16
Identities = 51/192 (26%), Positives = 91/192 (47%), Gaps = 15/192 (7%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQN------ILEPSYRGLLHAFSTIYQQEGF 160
W + G LA + + T+P DL KTRL +Q E YRG+LHA I ++EG
Sbjct: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
Query: 161 LALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSF 220
ALY G++ ++ + + Y +L++++ + +LP N L+ ++ T++
Sbjct: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
Query: 221 PFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYF 280
P + +K +MQAQS + G + F I + +G GLW G++ +
Sbjct: 126 PTDVLKIRMQAQSNTIQ---------GGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVV 176
Query: 281 GIMFSTFEFCKR 292
G+ ++ K+
Sbjct: 177 GVELPVYDITKK 188
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 88.6 bits (218), Expect = 7e-18
Identities = 57/188 (30%), Positives = 90/188 (47%), Gaps = 22/188 (11%)
Query: 111 MAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG---- 166
+AG G+ +V +P D +K RL +Q++ +P YRG LH F +I +QE L LY+G
Sbjct: 6 LAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSP 65
Query: 167 -VSLTVVGALPFSA-GSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFET 224
+ LT + AL F G+ L + + N F A A+ + P E
Sbjct: 66 LMGLTFINALVFGVQGNTLRALGHDSPLN----------QFLAGAAAGAIQCVICCPMEL 115
Query: 225 VKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMF 284
K ++Q Q G + G++DC QI +G+ G+ G+ + LL+ P FG+ F
Sbjct: 116 AKTRLQLQ------DAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYF 169
Query: 285 STFEFCKR 292
T++ R
Sbjct: 170 LTYDALTR 177
Score = 71.2 bits (173), Expect = 1e-12
Identities = 69/272 (25%), Positives = 116/272 (42%), Gaps = 15/272 (5%)
Query: 18 CAGLAGTLSLSLTAPLELATVLAQV-GVVRGHARGPWATGHRVWRAEGLRALWKGNAVAC 76
CAG G + + P + V QV V + RG + + E + L+KG
Sbjct: 9 CAG--GVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPL 66
Query: 77 LRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIM 136
+ L +A+ + LGH S + +AG+ AG + ++ P +L KTRL +
Sbjct: 67 MGLTFINALVFGVQGNTLRA----LGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQL 122
Query: 137 QNI-LEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEK-IWNG 194
Q+ +Y+G L + IY EG + RG+ T++ P L Y L + +
Sbjct: 123 QDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCE 182
Query: 195 PRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFR 254
P D+ +P+ + V+ ++P + VK ++QA G + G +DC
Sbjct: 183 PGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADG-----LRGAP-RYRGILDCVH 236
Query: 255 QIVKAQGVLGLWNGLTANLLKIVPYFGIMFST 286
Q +A+G GL + LL+ P F+T
Sbjct: 237 QSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 204 NFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVL 263
+F C + PF+TVK ++Q QS P + G + CF+ I+K + VL
Sbjct: 4 DFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKP-------QYRGTLHCFKSIIKQESVL 56
Query: 264 GLWNGLTANLLKIVPYFGIMF 284
GL+ GL + L+ + ++F
Sbjct: 57 GLYKGLGSPLMGLTFINALVF 77
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 87.4 bits (215), Expect = 2e-17
Identities = 77/294 (26%), Positives = 130/294 (44%), Gaps = 21/294 (7%)
Query: 11 TGGQRLLCAGLAGTLSLSLTAPLELATVLAQV-----GVVRGHA----RGPWATGHRVWR 61
T + L AG A ++ +T PL+ A V Q+ G VR A RG T + R
Sbjct: 12 TATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVR 71
Query: 62 AEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVST 121
EG R+L+ G R ++V++ Y +T H S S ++AGS G ++
Sbjct: 72 TEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAV 131
Query: 122 IVTYPTDLIKTRLIMQNILEPS--YRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSA 179
V PTD++K R Q Y+ ++A+ TI ++EGF L++G S V +
Sbjct: 132 AVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIVNC 191
Query: 180 GSLLVY-MNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPH 238
L+ Y + + + LP +F + A T ++ P + VK + Y+
Sbjct: 192 AELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTR------YMNS 245
Query: 239 SGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
+ G +S A C +++ +G + G + L++ + +MF T+E KR
Sbjct: 246 ALG---QYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 296
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 86.3 bits (212), Expect = 4e-17
Identities = 81/284 (28%), Positives = 133/284 (46%), Gaps = 18/284 (6%)
Query: 20 GLAGTLSLSLTAPLELATVLAQVGVVRGHAR-------GPWATGHRVWRAEGLRALWKGN 72
GLA ++ T P++L QV AR G + R+ + EG+ AL+ G
Sbjct: 48 GLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGI 107
Query: 73 AVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKT 132
A A LR +++ Y+ LF + L + +++ G ++G++S+ + PTD++K
Sbjct: 108 APALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKI 167
Query: 133 RLIMQNILEPSYRG-LLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEK- 190
R+ Q L ++G ++ +F IYQQEG L+RGV T A L VY +K
Sbjct: 168 RMQAQGSL---FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKH 224
Query: 191 -IWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGA 249
I +G L +F + S P + V+ +M Q + H VD+ + G
Sbjct: 225 LILSGMMGDTILT-HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGH---VDL-YKGT 279
Query: 250 VDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRI 293
VD ++ K +G L+ G N L++ P+ I F T+E KR+
Sbjct: 280 VDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
Score = 80.9 bits (198), Expect = 2e-15
Identities = 54/219 (24%), Positives = 101/219 (46%), Gaps = 17/219 (7%)
Query: 80 FPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQN- 138
F +AV ++ ++K + + G W + G LA +V+ T+P DL KTRL +Q
Sbjct: 16 FATAAVIVSGHQKSTTVSHEMSG--LNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQ 73
Query: 139 -----ILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWN 193
E YRG+ HA I ++EG LALY G++ ++ + + +Y +L++++
Sbjct: 74 SIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFV 133
Query: 194 GPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCF 253
+ +L N ++ ++ T++ P + +K +MQAQ S + F
Sbjct: 134 ERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGS---------MIGSF 184
Query: 254 RQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
I + +G GLW G+ + G+ ++ K+
Sbjct: 185 IDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKK 223
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 86.3 bits (212), Expect = 4e-17
Identities = 81/284 (28%), Positives = 133/284 (46%), Gaps = 18/284 (6%)
Query: 20 GLAGTLSLSLTAPLELATVLAQVGVVRGHAR-------GPWATGHRVWRAEGLRALWKGN 72
GLA ++ T P++L QV AR G + R+ + EG+ AL+ G
Sbjct: 45 GLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGI 104
Query: 73 AVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKT 132
A A LR +++ Y+ LF + L + +++ G ++G++S+ + PTD++K
Sbjct: 105 APALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKI 164
Query: 133 RLIMQNILEPSYRG-LLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEK- 190
R+ Q L ++G ++ +F IYQQEG L+RGV T A L VY +K
Sbjct: 165 RMQAQGSL---FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKH 221
Query: 191 -IWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGA 249
I +G L +F + S P + V+ +M Q + H VD+ + G
Sbjct: 222 LILSGMMGDTILT-HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGH---VDL-YKGT 276
Query: 250 VDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRI 293
VD ++ K +G L+ G N L++ P+ I F T+E KR+
Sbjct: 277 VDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 320
Score = 79.7 bits (195), Expect = 3e-15
Identities = 49/192 (25%), Positives = 89/192 (46%), Gaps = 15/192 (7%)
Query: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQN------ILEPSYRGLLHAFSTIYQQEGF 160
W + G LA +V+ T+P DL KTRL +Q E YRG+ HA I ++EG
Sbjct: 38 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGV 97
Query: 161 LALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSF 220
LALY G++ ++ + + +Y +L++++ + +L N ++ ++ T++
Sbjct: 98 LALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIAN 157
Query: 221 PFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYF 280
P + +K +MQAQ S + F I + +G GLW G+ +
Sbjct: 158 PTDVLKIRMQAQGSLFQGS---------MIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVV 208
Query: 281 GIMFSTFEFCKR 292
G+ ++ K+
Sbjct: 209 GVELPVYDITKK 220
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 85.9 bits (211), Expect = 5e-17
Identities = 70/295 (23%), Positives = 128/295 (43%), Gaps = 25/295 (8%)
Query: 15 RLLCAGLAGTLSLSLTAPLELA---------TVLAQVGVVRGHA---RGPWATGHRVWRA 62
+ L +G A T++ T PL+L LA++G + RG T +
Sbjct: 22 KFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEE 81
Query: 63 EGLRALWKGNAVACLRLFPCSAVQLAAYRKF--VVLFTDDLGHISQWSSIMAGSLAGMVS 120
EG LW+G A R S ++ Y VV + H W S++ G +AG++
Sbjct: 82 EGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGMMAGVIG 141
Query: 121 TIVTYPTDLIKTRLIMQNILEPS-----YRGLLHAFSTIYQQEGFLALYRGVSLTVVGAL 175
+ PTDL+K ++ M+ + +RG+ HAF+ I + G L+ G + A
Sbjct: 142 QFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQRAA 201
Query: 176 PFSAGSLLVYMNLEK--IWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQS 233
+ G L Y ++ + N P + + +++C + V L P + +K ++ Q
Sbjct: 202 LVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLC-SGLVASILGTPADVIKSRIMNQP 260
Query: 234 PYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFE 288
G + + + DC Q V+ +G + L+ G + L++ P+ + + T+E
Sbjct: 261 ---RDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYE 312
Score = 70.9 bits (172), Expect = 2e-12
Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 15/179 (8%)
Query: 108 SSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNIL-----------EPSYRGLLHAFSTIYQ 156
S + A V+ + T+P DL KTRL MQ YRG++ I +
Sbjct: 21 SKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIE 80
Query: 157 QEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPR--DQFSLPQNFANVCLAAAV 214
+EGFL L++GV+ + + +S G ++ Y +L ++ G + + L ++ +A +
Sbjct: 81 EEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGMMAGVI 140
Query: 215 TQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANL 273
Q L+ P + VK +MQ + G + F G F +I+ G+ GLW G N+
Sbjct: 141 GQFLANPTDLVKVQMQMEGK--RKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNI 197
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/185 (27%), Positives = 83/185 (44%), Gaps = 20/185 (10%)
Query: 21 LAGTLSLSLTAPLELATVLAQVGVVRG------HARGPWATGHRVWRAEGLRALWKGNAV 74
+AG + L P +L V Q+ R RG ++ G+R LW G
Sbjct: 136 MAGVIGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVP 195
Query: 75 ACLRLFPCSAVQLAAY---RKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIK 131
R + L Y + ++VL T +I ++ +G+V++I+ P D+IK
Sbjct: 196 NIQRAALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHG--LSSLCSGLVASILGTPADVIK 253
Query: 132 TRLIMQNILEPSYRGLLHAFST-----IYQQEGFLALYRGVSLTVVGALPFSAGSLLVYM 186
+R IM + RGLL+ ST Q EGF++LY+G + + P+ S++ ++
Sbjct: 254 SR-IMNQPRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPW---SMVFWL 309
Query: 187 NLEKI 191
EKI
Sbjct: 310 TYEKI 314
Score = 37.4 bits (85), Expect = 0.019
Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 211 AAAVTQTLSFPFETVKRKMQAQSPY----LPHSGGVDVHFSGAVDCFRQIVKAQGVLGLW 266
AA V + +FP + K ++Q Q L + G V I++ +G L LW
Sbjct: 29 AATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEEGFLKLW 88
Query: 267 NGLTANLLKIVPYFGIMFSTFEFCKRI 293
G+T + + V Y G T+E + +
Sbjct: 89 QGVTPAIYRHVVYSGGRMVTYEHLREV 115
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 85.9 bits (211), Expect = 5e-17
Identities = 74/292 (25%), Positives = 128/292 (43%), Gaps = 29/292 (9%)
Query: 15 RLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAV 74
+L+ G+AG + ++ P++LA Q + +G + RAEG +++G AV
Sbjct: 11 KLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAV 70
Query: 75 ACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRL 134
+ P A++LAA F L +D + ++AG AGM +VT P +++K +L
Sbjct: 71 NLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQL 130
Query: 135 IMQNILEPSYRGLLHAFST-----------------------IYQQEGFLALYRGVSLTV 171
L ++G A ST + + +G LYRG+ T+
Sbjct: 131 QDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATL 190
Query: 172 VGALPFSAGSLLVYMNLEKI-WNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQ 230
+ +PFS ++ NL + +N + S +F + C+A ++ P + +K ++Q
Sbjct: 191 LRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQ 250
Query: 231 AQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGI 282
L G D+ +SG DC R++ +G G L I P FGI
Sbjct: 251 TLKKGL----GEDM-YSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGI 297
Score = 62.4 bits (150), Expect = 6e-10
Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 17/200 (8%)
Query: 104 ISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLAL 163
+S + ++ G +AG+V +P DL KTRL Q+ + Y+G++ + EGF +
Sbjct: 6 LSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHG-KAMYKGMIDCLMKTARAEGFFGM 64
Query: 164 YRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFE 223
YRG ++ + P A L ++ Q +L C A ++ P E
Sbjct: 65 YRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPME 124
Query: 224 TVKRKMQ-AQSPYLPHSGGVDV------HFSGAVDCFR---------QIVKAQGVLGLWN 267
+K ++Q A + H G + +G+ R ++++ QG+ GL+
Sbjct: 125 MLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYR 184
Query: 268 GLTANLLKIVPYFGIMFSTF 287
GL A LL+ +P+ I F F
Sbjct: 185 GLGATLLRDIPFSIIYFPLF 204
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 8/96 (8%)
Query: 200 SLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKA 259
S+ N +A V T FP + K ++Q Q H + + G +DC + +A
Sbjct: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQ-----HGKAM---YKGMIDCLMKTARA 58
Query: 260 QGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICL 295
+G G++ G NL + P I + +F +R+ +
Sbjct: 59 EGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLM 94
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,537,256
Number of Sequences: 37866
Number of extensions: 509667
Number of successful extensions: 1997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1431
Number of HSP's gapped (non-prelim): 193
length of query: 341
length of database: 18,247,518
effective HSP length: 103
effective length of query: 238
effective length of database: 14,347,320
effective search space: 3414662160
effective search space used: 3414662160
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.