Guide to the Human Genome
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Search of human proteins with 21687043

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
         (223 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...   451   e-127
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...   451   e-127
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...   451   e-127
gi|9910432 dual specificity phosphatase 22 [Homo sapiens]              92   4e-19
gi|4758206 dual specificity phosphatase 2 [Homo sapiens]               92   5e-19
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi...    91   1e-18
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               89   2e-18
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]             89   2e-18
gi|4503421 dual specificity phosphatase 9 [Homo sapiens]               87   9e-18
gi|37674210 slingshot 2 [Homo sapiens]                                 86   3e-17
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    82   3e-16
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    82   3e-16
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             81   6e-16
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]     81   6e-16
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]    81   6e-16
gi|239047414 slingshot 1 isoform 1 [Homo sapiens]                      80   1e-15
gi|239047498 slingshot 1 isoform 3 [Homo sapiens]                      80   1e-15
gi|239047441 slingshot 1 isoform 2 [Homo sapiens]                      80   1e-15
gi|238231453 dual specificity phosphatase 7 [Homo sapiens]             80   2e-15
gi|62865890 dual specificity phosphatase 5 [Homo sapiens]              80   2e-15
gi|239582767 slingshot homolog 3 [Homo sapiens]                        79   4e-15
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]    79   4e-15
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              76   2e-14
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi...    73   2e-13
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi...    73   2e-13
gi|4758208 dual specificity phosphatase 3 [Homo sapiens]               72   4e-13
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             70   1e-12
gi|122937243 dual specificity phosphatase 27 [Homo sapiens]            69   3e-12
gi|13128968 dual specificity phosphatase 26 [Homo sapiens]             66   3e-11
gi|56117818 muscle-restricted dual specificity phosphatase isofo...    63   2e-10

>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score =  451 bits (1160), Expect = e-127
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
           MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
Sbjct: 1   MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60

Query: 61  ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
           ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
Sbjct: 61  ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120

Query: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
           NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
Sbjct: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180

Query: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
           QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
Sbjct: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score =  451 bits (1160), Expect = e-127
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
           MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
Sbjct: 1   MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60

Query: 61  ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
           ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
Sbjct: 61  ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120

Query: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
           NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
Sbjct: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180

Query: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
           QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
Sbjct: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score =  451 bits (1160), Expect = e-127
 Identities = 223/223 (100%), Positives = 223/223 (100%)

Query: 1   MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
           MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
Sbjct: 1   MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60

Query: 61  ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
           ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
Sbjct: 61  ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120

Query: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
           NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
Sbjct: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180

Query: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
           QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
Sbjct: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223


>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
          Length = 184

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 55/147 (37%), Positives = 80/147 (54%), Gaps = 8/147 (5%)

Query: 25  MRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLV 84
           M   M +ILPGL++G +  A  ++   L K+ +THI+ +  +      +P  + + +YL 
Sbjct: 1   MGNGMNKILPGLYIGNFKDARDAEQ--LSKNKVTHILSVHDSA-----RPMLEGV-KYLC 52

Query: 85  LDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYR 144
           +  AD+P +N+ R F  + +FI      G   LVH  AG+SRS   VIAYIM      + 
Sbjct: 53  IPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWE 112

Query: 145 DAFAYVQERRFCINPNAGFVHQLQEYE 171
           DA   V+  R C NPN GF  QLQE+E
Sbjct: 113 DALHTVRAGRSCANPNVGFQRQLQEFE 139


>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
          Length = 314

 Score = 91.7 bits (226), Expect = 5e-19
 Identities = 60/142 (42%), Positives = 85/142 (59%), Gaps = 9/142 (6%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIAD 89
           EILP LFLG  S +  S L  LQ  GIT ++    N+ A+   PN F+ LFRY  + + D
Sbjct: 175 EILPYLFLG--SCSHSSDLQGLQACGITAVL----NVSASC--PNHFEGLFRYKSIPVED 226

Query: 90  NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
           N +  I  +F     FID     GG+VLVH  AGISRSA   +AY+M++  ++  +AF +
Sbjct: 227 NQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDF 286

Query: 150 VQERRFCINPNAGFVHQLQEYE 171
           V++RR  I+PN  F+ QL ++E
Sbjct: 287 VKQRRGVISPNFSFMGQLLQFE 308


>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
           sapiens]
          Length = 217

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 53/140 (37%), Positives = 79/140 (56%), Gaps = 7/140 (5%)

Query: 32  ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
           I P L LG   +A    L  L+K+ +THI+ +   +E  F+       F Y  + I D P
Sbjct: 69  IKPWLLLGSQDAA--HDLDTLKKNKVTHILNVAYGVENAFLSD-----FTYKSISILDLP 121

Query: 92  VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
             NI+ +FP   EFI+ + +  G VLVH NAG+SR+AA VI ++M +    +  AF+ V+
Sbjct: 122 ETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVK 181

Query: 152 ERRFCINPNAGFVHQLQEYE 171
             R  I PN+GF+ QL+ Y+
Sbjct: 182 NARPSICPNSGFMEQLRTYQ 201


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 60/148 (40%), Positives = 86/148 (58%), Gaps = 11/148 (7%)

Query: 31  EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
           EILP L+LG  Y ++ K  L  L   GIT +I    N+ AN   PN F+  ++Y  + + 
Sbjct: 176 EILPFLYLGSAYHASRKDMLDAL---GITALI----NVSANC--PNHFEGHYQYKSIPVE 226

Query: 89  DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
           DN   +I  +F    +FID     GG+V VH  AGISRSA   +AY+M T  +K  +AF 
Sbjct: 227 DNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFE 286

Query: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
           +V++RR  I+PN  F+ QL ++E+  LA
Sbjct: 287 FVKQRRSIISPNFSFMGQLLQFESQVLA 314


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 54/143 (37%), Positives = 83/143 (58%), Gaps = 6/143 (4%)

Query: 29  MQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIA 88
           +  ILP L+LG     +   L  + ++GI++++    N   +  KP+F    R++ + I 
Sbjct: 161 LTRILPHLYLGSQKDVLNKDL--MTQNGISYVL----NASNSCPKPDFICESRFMRVPIN 214

Query: 89  DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
           DN  E ++ +   + EFID +     +V+VH  AGISRSA   IAYIM+T GM   DA+ 
Sbjct: 215 DNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYR 274

Query: 149 YVQERRFCINPNAGFVHQLQEYE 171
           +V++RR  I+PN  F+ QL EYE
Sbjct: 275 FVKDRRPSISPNFNFLGQLLEYE 297


>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
          Length = 384

 Score = 87.4 bits (215), Expect = 9e-18
 Identities = 53/141 (37%), Positives = 81/141 (57%), Gaps = 5/141 (3%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
           +ILP L+LG  S+   + L  L K GI +I+ +  N+  NF + N    F Y  + I+D+
Sbjct: 206 QILPNLYLG--SARDSANLESLAKLGIRYILNVTPNLP-NFFEKNGD--FHYKQIPISDH 260

Query: 91  PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
             +N+ RFFP   EFID +L     VLVH  AG+SRS    +AY+M+   +   DA+  V
Sbjct: 261 WSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLV 320

Query: 151 QERRFCINPNAGFVHQLQEYE 171
           + ++  I+PN  F+ QL ++E
Sbjct: 321 KRKKSNISPNFNFMGQLLDFE 341


>gi|37674210 slingshot 2 [Homo sapiens]
          Length = 1423

 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 53/146 (36%), Positives = 82/146 (56%), Gaps = 7/146 (4%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
           +I   +FLG   +A  S L  LQ  G+ +I+ + + I+ NF    F  +F Y  + + D 
Sbjct: 310 QIFEHVFLGSEWNA--SNLEDLQNRGVRYILNVTREID-NF----FPGVFEYHNIRVYDE 362

Query: 91  PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
              +++ ++  T +FI  + + G K LVH   G+SRSA+ VIAY M+ +G     A+ YV
Sbjct: 363 EATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYV 422

Query: 151 QERRFCINPNAGFVHQLQEYEAIYLA 176
           +ERR    PN  F+ QL+EY+ I LA
Sbjct: 423 KERRTVTKPNPSFMRQLEEYQGILLA 448


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 58/158 (36%), Positives = 79/158 (50%), Gaps = 8/158 (5%)

Query: 25  MRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLV 84
           M   M ++LPGL+LG +  A    L  L ++ ITHII I ++ +     P  Q +  YL 
Sbjct: 1   MGNGMTKVLPGLYLGNFIDA--KDLDQLGRNKITHIISIHESPQ-----PLLQDI-TYLR 52

Query: 85  LDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYR 144
           + +AD P   I + F     FI      GG  LVH  AGISRS   V AY+M   G+ +R
Sbjct: 53  IPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWR 112

Query: 145 DAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQM 182
           D    ++  R   NPN GF  QL+E+      KL  Q+
Sbjct: 113 DVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQL 150


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 53/158 (33%), Positives = 86/158 (54%), Gaps = 5/158 (3%)

Query: 28  EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
           E+  ILP LFLG    A    L  +Q+  I ++I +  ++     +     LF Y  L  
Sbjct: 321 ELTPILPFLFLGNEQDAQD--LDTMQRLNIGYVINVTTHLPLYHYEKG---LFNYKRLPA 375

Query: 88  ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
            D+  +N+ ++F    EFI+ + Q G  +L+H  AG+SRSA  VIAY+M+   M   DA+
Sbjct: 376 TDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 435

Query: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
            +V+ +R  I+PN  F+ QL E+E      +T ++++P
Sbjct: 436 KFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 473


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 81.3 bits (199), Expect = 6e-16
 Identities = 50/140 (35%), Positives = 79/140 (56%), Gaps = 6/140 (4%)

Query: 32  ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
           ILP L+LG     +  +L  +Q++GI +++    N      KP+F     +L + + D+ 
Sbjct: 162 ILPNLYLGCQRDVLNKEL--MQQNGIGYVL----NASNTCPKPDFIPESHFLRVPVNDSF 215

Query: 92  VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
            E I+ +   + +FI+ +    G VLVH  AGISRSA   IAYIM+   M   +A+ +V+
Sbjct: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275

Query: 152 ERRFCINPNAGFVHQLQEYE 171
           E+R  I+PN  F+ QL +YE
Sbjct: 276 EKRPTISPNFNFLGQLLDYE 295


>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
          Length = 394

 Score = 81.3 bits (199), Expect = 6e-16
 Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 11/148 (7%)

Query: 31  EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
           EILP L+LG  Y +A +  L  L   GIT ++ +  +       PN F+  ++Y  + + 
Sbjct: 198 EILPFLYLGSAYHAARRDMLDAL---GITALLNVSSDC------PNHFEGHYQYKCIPVE 248

Query: 89  DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
           DN   +I  +F    E+ID      G+VLVH  AGISRSA   +AY+M    ++  +AF 
Sbjct: 249 DNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFE 308

Query: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
           +V++RR  I+PN  F+ QL ++E+  LA
Sbjct: 309 FVKQRRSIISPNFSFMGQLLQFESQVLA 336


>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
          Length = 303

 Score = 81.3 bits (199), Expect = 6e-16
 Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 11/148 (7%)

Query: 31  EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
           EILP L+LG  Y +A +  L  L   GIT ++ +  +       PN F+  ++Y  + + 
Sbjct: 107 EILPFLYLGSAYHAARRDMLDAL---GITALLNVSSDC------PNHFEGHYQYKCIPVE 157

Query: 89  DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
           DN   +I  +F    E+ID      G+VLVH  AGISRSA   +AY+M    ++  +AF 
Sbjct: 158 DNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFE 217

Query: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
           +V++RR  I+PN  F+ QL ++E+  LA
Sbjct: 218 FVKQRRSIISPNFSFMGQLLQFESQVLA 245


>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
          Length = 1049

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)

Query: 32  ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
           I   L+LG   +A  S L  LQ  G+ +I+ + + I+ NF    F  LF Y  + + D  
Sbjct: 312 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 364

Query: 92  VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
             +++  +     FI+ + +   K LVH   G+SRSA+ VIAY M+ FG     A+ YV+
Sbjct: 365 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 424

Query: 152 ERRFCINPNAGFVHQLQEYEAI 173
           ++R    PNAGF+ QL EYE I
Sbjct: 425 QKRSITRPNAGFMRQLSEYEGI 446


>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
          Length = 703

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)

Query: 32  ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
           I   L+LG   +A  S L  LQ  G+ +I+ + + I+ NF    F  LF Y  + + D  
Sbjct: 323 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 375

Query: 92  VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
             +++  +     FI+ + +   K LVH   G+SRSA+ VIAY M+ FG     A+ YV+
Sbjct: 376 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 435

Query: 152 ERRFCINPNAGFVHQLQEYEAI 173
           ++R    PNAGF+ QL EYE I
Sbjct: 436 QKRSITRPNAGFMRQLSEYEGI 457


>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
          Length = 692

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)

Query: 32  ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
           I   L+LG   +A  S L  LQ  G+ +I+ + + I+ NF    F  LF Y  + + D  
Sbjct: 312 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 364

Query: 92  VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
             +++  +     FI+ + +   K LVH   G+SRSA+ VIAY M+ FG     A+ YV+
Sbjct: 365 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 424

Query: 152 ERRFCINPNAGFVHQLQEYEAI 173
           ++R    PNAGF+ QL EYE I
Sbjct: 425 QKRSITRPNAGFMRQLSEYEGI 446


>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
          Length = 419

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
           +ILP L+LG    +  + L VL K+GI +I+ +  N+   F        F Y  + I+D+
Sbjct: 247 QILPYLYLGCAKDS--TNLDVLGKYGIKYILNVTPNLPNAF---EHGGEFTYKQIPISDH 301

Query: 91  PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
             +N+ +FFP    FID +      VLVH  AGISRS    +AY+M+   +   DA+ +V
Sbjct: 302 WSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFV 361

Query: 151 QERRFCINPNAGFVHQLQEYE 171
           + ++  I+PN  F+ QL ++E
Sbjct: 362 KRKKSNISPNFNFMGQLLDFE 382


>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
          Length = 384

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 53/143 (37%), Positives = 79/143 (55%), Gaps = 9/143 (6%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICI-RQNIEANFIKPNFQQLFRYLVLDIAD 89
           EILP L+LG  S+   SK   L    IT ++ + R+  EA            Y  + + D
Sbjct: 181 EILPFLYLG--SAYHASKCEFLANLHITALLNVSRRTSEACATH------LHYKWIPVED 232

Query: 90  NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
           +   +I   F    +FID   + GGKVLVH  AGISRS    +AY+M+T   + ++AF Y
Sbjct: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292

Query: 150 VQERRFCINPNAGFVHQLQEYEA 172
           +++RR  ++PN GF+ QL +YE+
Sbjct: 293 IKQRRSMVSPNFGFMGQLLQYES 315


>gi|239582767 slingshot homolog 3 [Homo sapiens]
          Length = 659

 Score = 78.6 bits (192), Expect = 4e-15
 Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 7/151 (4%)

Query: 26  RREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVL 85
           R     I P L+LG   +A  + L  LQ++ +THI+ + + I+ NF    + + F Y  +
Sbjct: 326 RDRASRIFPHLYLGSEWNA--ANLEELQRNRVTHILNMAREID-NF----YPERFTYHNV 378

Query: 86  DIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRD 145
            + D     ++  +  T  FI+ +   G  VLVH   G+SRSAA V+AY M+ +      
Sbjct: 379 RLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQ 438

Query: 146 AFAYVQERRFCINPNAGFVHQLQEYEAIYLA 176
           A  +VQE R    PN GF+ QLQ Y+ I  A
Sbjct: 439 ALRHVQELRPIARPNPGFLRQLQIYQGILTA 469


>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
          Length = 381

 Score = 78.6 bits (192), Expect = 4e-15
 Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
           EILP L+LG    +  + L VL++ GI +I+ +  N+   F        F+Y  + I+D+
Sbjct: 209 EILPFLYLGCAKDS--TNLDVLEEFGIKYILNVTPNLPNLFENAGE---FKYKQIPISDH 263

Query: 91  PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
             +N+ +FFP    FID +      VLVH  AGISRS    +AY+M+   +   DA+  V
Sbjct: 264 WSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIV 323

Query: 151 QERRFCINPNAGFVHQLQEYE 171
           + ++  I+PN  F+ QL ++E
Sbjct: 324 KMKKSNISPNFNFMGQLLDFE 344


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 57/154 (37%), Positives = 77/154 (50%), Gaps = 9/154 (5%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQ-QLFRYLVLDIAD 89
           +I   LFLG  S A    L  LQ  GIT   CI   + A    PNF    F Y+ + +AD
Sbjct: 29  QITSSLFLGRGSVASNRHL--LQARGIT---CI---VNATIEIPNFNWPQFEYVKVPLAD 80

Query: 90  NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
            P   I  +F    + I    +  G  LVH  AG+SRSA   IAY+M+   +   +A+ +
Sbjct: 81  MPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNW 140

Query: 150 VQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMM 183
           V+ RR  I PN GF  QL +YE     K T++M+
Sbjct: 141 VKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMV 174


>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 40/107 (37%), Positives = 64/107 (59%)

Query: 79  LFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMET 138
           LF Y  L   D+  +N+ ++F    EFI+ + Q G  +L+H  AG+SRSA  VIAY+M+ 
Sbjct: 25  LFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKH 84

Query: 139 FGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
             M   DA+ +V+ +R  I+PN  F+ QL E+E      +T ++++P
Sbjct: 85  TRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 131


>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 73.2 bits (178), Expect = 2e-13
 Identities = 40/107 (37%), Positives = 64/107 (59%)

Query: 79  LFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMET 138
           LF Y  L   D+  +N+ ++F    EFI+ + Q G  +L+H  AG+SRSA  VIAY+M+ 
Sbjct: 25  LFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKH 84

Query: 139 FGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
             M   DA+ +V+ +R  I+PN  F+ QL E+E      +T ++++P
Sbjct: 85  TRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 131


>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
          Length = 185

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 51/145 (35%), Positives = 76/145 (52%), Gaps = 14/145 (9%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQ-------NIEANFIKPNFQQLFRYL 83
           E+ P +++G  ++++   +P LQK GITH++   +       N  ANF K +      YL
Sbjct: 32  EVTPRIYVG--NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSG---ITYL 86

Query: 84  VLDIADNPVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMK 142
            +   D    N+  +F    +FID +L Q  G+VLVH   G SRS   VIAY+M    M 
Sbjct: 87  GIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMD 146

Query: 143 YRDAFAYVQERRFCINPNAGFVHQL 167
            + A + V++ R  I PN GF+ QL
Sbjct: 147 VKSALSIVRQNRE-IGPNDGFLAQL 170


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 45/141 (31%), Positives = 72/141 (51%), Gaps = 6/141 (4%)

Query: 44  AMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTK 103
           A  +KL +L  + IT +I    N+    +   ++ + +Y+ + +AD+P   +  FF    
Sbjct: 34  AANNKL-MLSSNQITMVI----NVSVEVVNTLYEDI-QYMQVPVADSPNSRLCDFFDPIA 87

Query: 104 EFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGF 163
           + I       G+ L+H  AG+SRSAA  +AY+M+   M   DA  + +  R  I PN+GF
Sbjct: 88  DHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGF 147

Query: 164 VHQLQEYEAIYLAKLTIQMMS 184
             QL  YE     K T+ M+S
Sbjct: 148 WEQLIHYEFQLFGKNTVHMVS 168


>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
          Length = 1158

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 51/145 (35%), Positives = 76/145 (52%), Gaps = 7/145 (4%)

Query: 28  EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQ--LFRYLVL 85
           E+ E+ P +F+   S A+      L++ GITHI+         +  P F      +YL +
Sbjct: 133 EVDEVWPNVFIAEKSVAVNKGR--LKRLGITHILNAAHGTGV-YTGPEFYTGLEIQYLGV 189

Query: 86  DIADNPVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYR 144
           ++ D P  +I + F    EF+D +L    GKVLV    GISRSA  V+AY+M    M   
Sbjct: 190 EVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAIL 249

Query: 145 DAFAYVQERRFCINPNAGFVHQLQE 169
           +A   V+++R  I PN GF+ QL+E
Sbjct: 250 EALMTVRKKR-AIYPNEGFLKQLRE 273


>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
          Length = 211

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 47/138 (34%), Positives = 72/138 (52%), Gaps = 4/138 (2%)

Query: 31  EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
           E+ PGL+LG    A   +   L++ GITH++    +      +       RYL ++  D+
Sbjct: 64  EVWPGLYLGDQDMANNRR--ELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDS 121

Query: 91  PVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
           P  ++   F    +FI  +L Q GGK+LVH   G+SRSA  V+AY+M    +   +A   
Sbjct: 122 PAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKK 181

Query: 150 VQERRFCINPNAGFVHQL 167
           V++ R  I PN GF+ QL
Sbjct: 182 VKDHRGII-PNRGFLRQL 198


>gi|56117818 muscle-restricted dual specificity phosphatase isoform
           1 [Homo sapiens]
          Length = 188

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 47/141 (33%), Positives = 72/141 (51%), Gaps = 5/141 (3%)

Query: 29  MQEILPGLFLGPYSSAMKSKLPVLQKHGITHII-CIRQNIEANFIKPNFQQLFRYLVLDI 87
           + E+ P LF+G  ++A  +    L K GITH++    + +        +     YL +  
Sbjct: 38  VDEVWPNLFIGDAATA--NNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPA 95

Query: 88  ADNPVENIIRFFPMTKEFIDGSLQM-GGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDA 146
            D P  +I  +F    +FI  +L   G KVLVH   G+SRSA  V+AY+M    +  R A
Sbjct: 96  HDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQA 155

Query: 147 FAYVQERRFCINPNAGFVHQL 167
              V++ R+ + PN GF+HQL
Sbjct: 156 VITVRQHRW-VFPNRGFLHQL 175


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,929,670
Number of Sequences: 37866
Number of extensions: 309185
Number of successful extensions: 821
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 751
Number of HSP's gapped (non-prelim): 74
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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