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Search of human proteins with 21687043
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
(223 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 451 e-127
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 451 e-127
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 451 e-127
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 92 4e-19
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 92 5e-19
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 91 1e-18
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 89 2e-18
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 89 2e-18
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 87 9e-18
gi|37674210 slingshot 2 [Homo sapiens] 86 3e-17
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 82 3e-16
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 82 3e-16
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 81 6e-16
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 81 6e-16
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 81 6e-16
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 80 1e-15
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 80 1e-15
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 80 1e-15
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 80 2e-15
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 80 2e-15
gi|239582767 slingshot homolog 3 [Homo sapiens] 79 4e-15
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 79 4e-15
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 76 2e-14
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 73 2e-13
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 73 2e-13
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 72 4e-13
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 70 1e-12
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 69 3e-12
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 66 3e-11
gi|56117818 muscle-restricted dual specificity phosphatase isofo... 63 2e-10
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 451 bits (1160), Expect = e-127
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
Sbjct: 1 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
Query: 61 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
Sbjct: 61 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
Query: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
Sbjct: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
Query: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
Sbjct: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 451 bits (1160), Expect = e-127
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
Sbjct: 1 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
Query: 61 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
Sbjct: 61 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
Query: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
Sbjct: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
Query: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
Sbjct: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 451 bits (1160), Expect = e-127
Identities = 223/223 (100%), Positives = 223/223 (100%)
Query: 1 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI
Sbjct: 1 MEDVKLEFPSLPQCKEDAEEWTYPMRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHI 60
Query: 61 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG
Sbjct: 61 ICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHG 120
Query: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI
Sbjct: 121 NAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTI 180
Query: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG
Sbjct: 181 QMMSPLQIERSLSVHSGTTGSLKRTHEEEDDFGTMQVATAQNG 223
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 92.0 bits (227), Expect = 4e-19
Identities = 55/147 (37%), Positives = 80/147 (54%), Gaps = 8/147 (5%)
Query: 25 MRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLV 84
M M +ILPGL++G + A ++ L K+ +THI+ + + +P + + +YL
Sbjct: 1 MGNGMNKILPGLYIGNFKDARDAEQ--LSKNKVTHILSVHDSA-----RPMLEGV-KYLC 52
Query: 85 LDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYR 144
+ AD+P +N+ R F + +FI G LVH AG+SRS VIAYIM +
Sbjct: 53 IPAADSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWE 112
Query: 145 DAFAYVQERRFCINPNAGFVHQLQEYE 171
DA V+ R C NPN GF QLQE+E
Sbjct: 113 DALHTVRAGRSCANPNVGFQRQLQEFE 139
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 91.7 bits (226), Expect = 5e-19
Identities = 60/142 (42%), Positives = 85/142 (59%), Gaps = 9/142 (6%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIAD 89
EILP LFLG S + S L LQ GIT ++ N+ A+ PN F+ LFRY + + D
Sbjct: 175 EILPYLFLG--SCSHSSDLQGLQACGITAVL----NVSASC--PNHFEGLFRYKSIPVED 226
Query: 90 NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
N + I +F FID GG+VLVH AGISRSA +AY+M++ ++ +AF +
Sbjct: 227 NQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDF 286
Query: 150 VQERRFCINPNAGFVHQLQEYE 171
V++RR I+PN F+ QL ++E
Sbjct: 287 VKQRRGVISPNFSFMGQLLQFE 308
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 90.5 bits (223), Expect = 1e-18
Identities = 53/140 (37%), Positives = 79/140 (56%), Gaps = 7/140 (5%)
Query: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
I P L LG +A L L+K+ +THI+ + +E F+ F Y + I D P
Sbjct: 69 IKPWLLLGSQDAA--HDLDTLKKNKVTHILNVAYGVENAFLSD-----FTYKSISILDLP 121
Query: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
NI+ +FP EFI+ + + G VLVH NAG+SR+AA VI ++M + + AF+ V+
Sbjct: 122 ETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVK 181
Query: 152 ERRFCINPNAGFVHQLQEYE 171
R I PN+GF+ QL+ Y+
Sbjct: 182 NARPSICPNSGFMEQLRTYQ 201
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 89.4 bits (220), Expect = 2e-18
Identities = 60/148 (40%), Positives = 86/148 (58%), Gaps = 11/148 (7%)
Query: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
EILP L+LG Y ++ K L L GIT +I N+ AN PN F+ ++Y + +
Sbjct: 176 EILPFLYLGSAYHASRKDMLDAL---GITALI----NVSANC--PNHFEGHYQYKSIPVE 226
Query: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
DN +I +F +FID GG+V VH AGISRSA +AY+M T +K +AF
Sbjct: 227 DNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFE 286
Query: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 287 FVKQRRSIISPNFSFMGQLLQFESQVLA 314
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 89.4 bits (220), Expect = 2e-18
Identities = 54/143 (37%), Positives = 83/143 (58%), Gaps = 6/143 (4%)
Query: 29 MQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIA 88
+ ILP L+LG + L + ++GI++++ N + KP+F R++ + I
Sbjct: 161 LTRILPHLYLGSQKDVLNKDL--MTQNGISYVL----NASNSCPKPDFICESRFMRVPIN 214
Query: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
DN E ++ + + EFID + +V+VH AGISRSA IAYIM+T GM DA+
Sbjct: 215 DNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYR 274
Query: 149 YVQERRFCINPNAGFVHQLQEYE 171
+V++RR I+PN F+ QL EYE
Sbjct: 275 FVKDRRPSISPNFNFLGQLLEYE 297
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 87.4 bits (215), Expect = 9e-18
Identities = 53/141 (37%), Positives = 81/141 (57%), Gaps = 5/141 (3%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
+ILP L+LG S+ + L L K GI +I+ + N+ NF + N F Y + I+D+
Sbjct: 206 QILPNLYLG--SARDSANLESLAKLGIRYILNVTPNLP-NFFEKNGD--FHYKQIPISDH 260
Query: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
+N+ RFFP EFID +L VLVH AG+SRS +AY+M+ + DA+ V
Sbjct: 261 WSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLV 320
Query: 151 QERRFCINPNAGFVHQLQEYE 171
+ ++ I+PN F+ QL ++E
Sbjct: 321 KRKKSNISPNFNFMGQLLDFE 341
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 85.9 bits (211), Expect = 3e-17
Identities = 53/146 (36%), Positives = 82/146 (56%), Gaps = 7/146 (4%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
+I +FLG +A S L LQ G+ +I+ + + I+ NF F +F Y + + D
Sbjct: 310 QIFEHVFLGSEWNA--SNLEDLQNRGVRYILNVTREID-NF----FPGVFEYHNIRVYDE 362
Query: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
+++ ++ T +FI + + G K LVH G+SRSA+ VIAY M+ +G A+ YV
Sbjct: 363 EATDLLAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYV 422
Query: 151 QERRFCINPNAGFVHQLQEYEAIYLA 176
+ERR PN F+ QL+EY+ I LA
Sbjct: 423 KERRTVTKPNPSFMRQLEEYQGILLA 448
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 82.4 bits (202), Expect = 3e-16
Identities = 58/158 (36%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 25 MRREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLV 84
M M ++LPGL+LG + A L L ++ ITHII I ++ + P Q + YL
Sbjct: 1 MGNGMTKVLPGLYLGNFIDA--KDLDQLGRNKITHIISIHESPQ-----PLLQDI-TYLR 52
Query: 85 LDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYR 144
+ +AD P I + F FI GG LVH AGISRS V AY+M G+ +R
Sbjct: 53 IPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWR 112
Query: 145 DAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQM 182
D ++ R NPN GF QL+E+ KL Q+
Sbjct: 113 DVLEAIKATRPIANPNPGFRQQLEEFGWASSQKLRRQL 150
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 82.4 bits (202), Expect = 3e-16
Identities = 53/158 (33%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Query: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDI 87
E+ ILP LFLG A L +Q+ I ++I + ++ + LF Y L
Sbjct: 321 ELTPILPFLFLGNEQDAQD--LDTMQRLNIGYVINVTTHLPLYHYEKG---LFNYKRLPA 375
Query: 88 ADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAF 147
D+ +N+ ++F EFI+ + Q G +L+H AG+SRSA VIAY+M+ M DA+
Sbjct: 376 TDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 435
Query: 148 AYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
+V+ +R I+PN F+ QL E+E +T ++++P
Sbjct: 436 KFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 473
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 81.3 bits (199), Expect = 6e-16
Identities = 50/140 (35%), Positives = 79/140 (56%), Gaps = 6/140 (4%)
Query: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
ILP L+LG + +L +Q++GI +++ N KP+F +L + + D+
Sbjct: 162 ILPNLYLGCQRDVLNKEL--MQQNGIGYVL----NASNTCPKPDFIPESHFLRVPVNDSF 215
Query: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
E I+ + + +FI+ + G VLVH AGISRSA IAYIM+ M +A+ +V+
Sbjct: 216 CEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVK 275
Query: 152 ERRFCINPNAGFVHQLQEYE 171
E+R I+PN F+ QL +YE
Sbjct: 276 EKRPTISPNFNFLGQLLDYE 295
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 81.3 bits (199), Expect = 6e-16
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 11/148 (7%)
Query: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
EILP L+LG Y +A + L L GIT ++ + + PN F+ ++Y + +
Sbjct: 198 EILPFLYLGSAYHAARRDMLDAL---GITALLNVSSDC------PNHFEGHYQYKCIPVE 248
Query: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
DN +I +F E+ID G+VLVH AGISRSA +AY+M ++ +AF
Sbjct: 249 DNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFE 308
Query: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 309 FVKQRRSIISPNFSFMGQLLQFESQVLA 336
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 81.3 bits (199), Expect = 6e-16
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 11/148 (7%)
Query: 31 EILPGLFLGP-YSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPN-FQQLFRYLVLDIA 88
EILP L+LG Y +A + L L GIT ++ + + PN F+ ++Y + +
Sbjct: 107 EILPFLYLGSAYHAARRDMLDAL---GITALLNVSSDC------PNHFEGHYQYKCIPVE 157
Query: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
DN +I +F E+ID G+VLVH AGISRSA +AY+M ++ +AF
Sbjct: 158 DNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFE 217
Query: 149 YVQERRFCINPNAGFVHQLQEYEAIYLA 176
+V++RR I+PN F+ QL ++E+ LA
Sbjct: 218 FVKQRRSIISPNFSFMGQLLQFESQVLA 245
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 80.5 bits (197), Expect = 1e-15
Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Query: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
I L+LG +A S L LQ G+ +I+ + + I+ NF F LF Y + + D
Sbjct: 312 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 364
Query: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
+++ + FI+ + + K LVH G+SRSA+ VIAY M+ FG A+ YV+
Sbjct: 365 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 424
Query: 152 ERRFCINPNAGFVHQLQEYEAI 173
++R PNAGF+ QL EYE I
Sbjct: 425 QKRSITRPNAGFMRQLSEYEGI 446
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 80.5 bits (197), Expect = 1e-15
Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Query: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
I L+LG +A S L LQ G+ +I+ + + I+ NF F LF Y + + D
Sbjct: 323 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 375
Query: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
+++ + FI+ + + K LVH G+SRSA+ VIAY M+ FG A+ YV+
Sbjct: 376 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 435
Query: 152 ERRFCINPNAGFVHQLQEYEAI 173
++R PNAGF+ QL EYE I
Sbjct: 436 QKRSITRPNAGFMRQLSEYEGI 457
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 80.5 bits (197), Expect = 1e-15
Identities = 52/142 (36%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Query: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
I L+LG +A S L LQ G+ +I+ + + I+ NF F LF Y + + D
Sbjct: 312 IFDHLYLGSEWNA--SNLEELQGSGVDYILNVTREID-NF----FPGLFAYHNIRVYDEE 364
Query: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
+++ + FI+ + + K LVH G+SRSA+ VIAY M+ FG A+ YV+
Sbjct: 365 TTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVK 424
Query: 152 ERRFCINPNAGFVHQLQEYEAI 173
++R PNAGF+ QL EYE I
Sbjct: 425 QKRSITRPNAGFMRQLSEYEGI 446
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 79.7 bits (195), Expect = 2e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
+ILP L+LG + + L VL K+GI +I+ + N+ F F Y + I+D+
Sbjct: 247 QILPYLYLGCAKDS--TNLDVLGKYGIKYILNVTPNLPNAF---EHGGEFTYKQIPISDH 301
Query: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ +V
Sbjct: 302 WSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFV 361
Query: 151 QERRFCINPNAGFVHQLQEYE 171
+ ++ I+PN F+ QL ++E
Sbjct: 362 KRKKSNISPNFNFMGQLLDFE 382
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 79.7 bits (195), Expect = 2e-15
Identities = 53/143 (37%), Positives = 79/143 (55%), Gaps = 9/143 (6%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICI-RQNIEANFIKPNFQQLFRYLVLDIAD 89
EILP L+LG S+ SK L IT ++ + R+ EA Y + + D
Sbjct: 181 EILPFLYLG--SAYHASKCEFLANLHITALLNVSRRTSEACATH------LHYKWIPVED 232
Query: 90 NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
+ +I F +FID + GGKVLVH AGISRS +AY+M+T + ++AF Y
Sbjct: 233 SHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDY 292
Query: 150 VQERRFCINPNAGFVHQLQEYEA 172
+++RR ++PN GF+ QL +YE+
Sbjct: 293 IKQRRSMVSPNFGFMGQLLQYES 315
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 78.6 bits (192), Expect = 4e-15
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 7/151 (4%)
Query: 26 RREMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVL 85
R I P L+LG +A + L LQ++ +THI+ + + I+ NF + + F Y +
Sbjct: 326 RDRASRIFPHLYLGSEWNA--ANLEELQRNRVTHILNMAREID-NF----YPERFTYHNV 378
Query: 86 DIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRD 145
+ D ++ + T FI+ + G VLVH G+SRSAA V+AY M+ +
Sbjct: 379 RLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQ 438
Query: 146 AFAYVQERRFCINPNAGFVHQLQEYEAIYLA 176
A +VQE R PN GF+ QLQ Y+ I A
Sbjct: 439 ALRHVQELRPIARPNPGFLRQLQIYQGILTA 469
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 78.6 bits (192), Expect = 4e-15
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
EILP L+LG + + L VL++ GI +I+ + N+ F F+Y + I+D+
Sbjct: 209 EILPFLYLGCAKDS--TNLDVLEEFGIKYILNVTPNLPNLFENAGE---FKYKQIPISDH 263
Query: 91 PVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 150
+N+ +FFP FID + VLVH AGISRS +AY+M+ + DA+ V
Sbjct: 264 WSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIV 323
Query: 151 QERRFCINPNAGFVHQLQEYE 171
+ ++ I+PN F+ QL ++E
Sbjct: 324 KMKKSNISPNFNFMGQLLDFE 344
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 76.3 bits (186), Expect = 2e-14
Identities = 57/154 (37%), Positives = 77/154 (50%), Gaps = 9/154 (5%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQ-QLFRYLVLDIAD 89
+I LFLG S A L LQ GIT CI + A PNF F Y+ + +AD
Sbjct: 29 QITSSLFLGRGSVASNRHL--LQARGIT---CI---VNATIEIPNFNWPQFEYVKVPLAD 80
Query: 90 NPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
P I +F + I + G LVH AG+SRSA IAY+M+ + +A+ +
Sbjct: 81 MPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNW 140
Query: 150 VQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMM 183
V+ RR I PN GF QL +YE K T++M+
Sbjct: 141 VKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMV 174
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 73.2 bits (178), Expect = 2e-13
Identities = 40/107 (37%), Positives = 64/107 (59%)
Query: 79 LFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMET 138
LF Y L D+ +N+ ++F EFI+ + Q G +L+H AG+SRSA VIAY+M+
Sbjct: 25 LFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKH 84
Query: 139 FGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
M DA+ +V+ +R I+PN F+ QL E+E +T ++++P
Sbjct: 85 TRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 131
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 73.2 bits (178), Expect = 2e-13
Identities = 40/107 (37%), Positives = 64/107 (59%)
Query: 79 LFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMET 138
LF Y L D+ +N+ ++F EFI+ + Q G +L+H AG+SRSA VIAY+M+
Sbjct: 25 LFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKH 84
Query: 139 FGMKYRDAFAYVQERRFCINPNAGFVHQLQEYEAIYLAKLTIQMMSP 185
M DA+ +V+ +R I+PN F+ QL E+E +T ++++P
Sbjct: 85 TRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTP 131
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 72.0 bits (175), Expect = 4e-13
Identities = 51/145 (35%), Positives = 76/145 (52%), Gaps = 14/145 (9%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQ-------NIEANFIKPNFQQLFRYL 83
E+ P +++G ++++ +P LQK GITH++ + N ANF K + YL
Sbjct: 32 EVTPRIYVG--NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSG---ITYL 86
Query: 84 VLDIADNPVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMK 142
+ D N+ +F +FID +L Q G+VLVH G SRS VIAY+M M
Sbjct: 87 GIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMD 146
Query: 143 YRDAFAYVQERRFCINPNAGFVHQL 167
+ A + V++ R I PN GF+ QL
Sbjct: 147 VKSALSIVRQNRE-IGPNDGFLAQL 170
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 70.5 bits (171), Expect = 1e-12
Identities = 45/141 (31%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Query: 44 AMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTK 103
A +KL +L + IT +I N+ + ++ + +Y+ + +AD+P + FF
Sbjct: 34 AANNKL-MLSSNQITMVI----NVSVEVVNTLYEDI-QYMQVPVADSPNSRLCDFFDPIA 87
Query: 104 EFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFCINPNAGF 163
+ I G+ L+H AG+SRSAA +AY+M+ M DA + + R I PN+GF
Sbjct: 88 DHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGF 147
Query: 164 VHQLQEYEAIYLAKLTIQMMS 184
QL YE K T+ M+S
Sbjct: 148 WEQLIHYEFQLFGKNTVHMVS 168
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 68.9 bits (167), Expect = 3e-12
Identities = 51/145 (35%), Positives = 76/145 (52%), Gaps = 7/145 (4%)
Query: 28 EMQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQ--LFRYLVL 85
E+ E+ P +F+ S A+ L++ GITHI+ + P F +YL +
Sbjct: 133 EVDEVWPNVFIAEKSVAVNKGR--LKRLGITHILNAAHGTGV-YTGPEFYTGLEIQYLGV 189
Query: 86 DIADNPVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYR 144
++ D P +I + F EF+D +L GKVLV GISRSA V+AY+M M
Sbjct: 190 EVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNMAIL 249
Query: 145 DAFAYVQERRFCINPNAGFVHQLQE 169
+A V+++R I PN GF+ QL+E
Sbjct: 250 EALMTVRKKR-AIYPNEGFLKQLRE 273
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 65.9 bits (159), Expect = 3e-11
Identities = 47/138 (34%), Positives = 72/138 (52%), Gaps = 4/138 (2%)
Query: 31 EILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADN 90
E+ PGL+LG A + L++ GITH++ + + RYL ++ D+
Sbjct: 64 EVWPGLYLGDQDMANNRR--ELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDS 121
Query: 91 PVENIIRFFPMTKEFIDGSL-QMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAY 149
P ++ F +FI +L Q GGK+LVH G+SRSA V+AY+M + +A
Sbjct: 122 PAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKK 181
Query: 150 VQERRFCINPNAGFVHQL 167
V++ R I PN GF+ QL
Sbjct: 182 VKDHRGII-PNRGFLRQL 198
>gi|56117818 muscle-restricted dual specificity phosphatase isoform
1 [Homo sapiens]
Length = 188
Score = 63.2 bits (152), Expect = 2e-10
Identities = 47/141 (33%), Positives = 72/141 (51%), Gaps = 5/141 (3%)
Query: 29 MQEILPGLFLGPYSSAMKSKLPVLQKHGITHII-CIRQNIEANFIKPNFQQLFRYLVLDI 87
+ E+ P LF+G ++A + L K GITH++ + + + YL +
Sbjct: 38 VDEVWPNLFIGDAATA--NNRFELWKLGITHVLNAAHKGLYCQGGPDFYGSSVSYLGVPA 95
Query: 88 ADNPVENIIRFFPMTKEFIDGSLQM-GGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDA 146
D P +I +F +FI +L G KVLVH G+SRSA V+AY+M + R A
Sbjct: 96 HDLPDFDISAYFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQA 155
Query: 147 FAYVQERRFCINPNAGFVHQL 167
V++ R+ + PN GF+HQL
Sbjct: 156 VITVRQHRW-VFPNRGFLHQL 175
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,929,670
Number of Sequences: 37866
Number of extensions: 309185
Number of successful extensions: 821
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 751
Number of HSP's gapped (non-prelim): 74
length of query: 223
length of database: 18,247,518
effective HSP length: 98
effective length of query: 125
effective length of database: 14,536,650
effective search space: 1817081250
effective search space used: 1817081250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.