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Search of human proteins with 215599070
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215599070 evolutionarily conserved signaling intermediate in
Toll pathway isoform 3 [Homo sapiens]
(217 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215599070 evolutionarily conserved signaling intermediate in ... 454 e-128
gi|20149633 evolutionarily conserved signaling intermediate in T... 392 e-109
gi|215599065 evolutionarily conserved signaling intermediate in ... 75 4e-14
gi|8922699 CNDP dipeptidase 2 [Homo sapiens] 30 1.2
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 30 1.6
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ... 30 1.6
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 30 1.6
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 30 1.6
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 30 1.6
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 30 1.6
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s... 30 1.6
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ... 30 1.6
gi|49087132 sal-like 2 [Homo sapiens] 29 2.7
gi|156938257 leucine rich repeat containing 16B [Homo sapiens] 29 2.7
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 29 3.5
gi|157671953 solute carrier family 4, anion exchanger, member 3 ... 29 3.5
gi|62198237 DNA-directed DNA polymerase epsilon [Homo sapiens] 28 4.6
gi|39812378 RAN binding protein 9 [Homo sapiens] 28 7.8
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 28 7.8
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 28 7.8
gi|7662164 hypothetical protein LOC9764 [Homo sapiens] 28 7.8
>gi|215599070 evolutionarily conserved signaling intermediate in
Toll pathway isoform 3 [Homo sapiens]
Length = 217
Score = 454 bits (1169), Expect = e-128
Identities = 217/217 (100%), Positives = 217/217 (100%)
Query: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPLPKDSTGAADPPQPHIVGIQSPDQQA 60
MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPLPKDSTGAADPPQPHIVGIQSPDQQA
Sbjct: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPLPKDSTGAADPPQPHIVGIQSPDQQA 60
Query: 61 ALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPMQLDL 120
ALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPMQLDL
Sbjct: 61 ALARHNPARPVFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPMQLDL 120
Query: 121 EYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQGLQETNPTLAQIPVVFRLA 180
EYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQGLQETNPTLAQIPVVFRLA
Sbjct: 121 EYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQGLQETNPTLAQIPVVFRLA 180
Query: 181 GSTRELQTSSAGLEEPPLPEDHQEEDDNLQRQQQGQS 217
GSTRELQTSSAGLEEPPLPEDHQEEDDNLQRQQQGQS
Sbjct: 181 GSTRELQTSSAGLEEPPLPEDHQEEDDNLQRQQQGQS 217
>gi|20149633 evolutionarily conserved signaling intermediate in Toll
pathway isoform 1 [Homo sapiens]
Length = 431
Score = 392 bits (1006), Expect = e-109
Identities = 187/189 (98%), Positives = 188/189 (99%)
Query: 29 SISQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYY 88
+I QVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYY
Sbjct: 243 TIYQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEGPFSLWLRNKCVYY 302
Query: 89 HILRADLLPPEEREVEETPEEWNLYYPMQLDLEYVRSGWDNYEFDINEVEEGPVFAMCMA 148
HILRADLLPPEEREVEETPEEWNLYYPMQLDLEYVRSGWDNYEFDINEVEEGPVFAMCMA
Sbjct: 303 HILRADLLPPEEREVEETPEEWNLYYPMQLDLEYVRSGWDNYEFDINEVEEGPVFAMCMA 362
Query: 149 GAHDQATMAKWIQGLQETNPTLAQIPVVFRLAGSTRELQTSSAGLEEPPLPEDHQEEDDN 208
GAHDQATMAKWIQGLQETNPTLAQIPVVFRLAGSTRELQTSSAGLEEPPLPEDHQEEDDN
Sbjct: 363 GAHDQATMAKWIQGLQETNPTLAQIPVVFRLAGSTRELQTSSAGLEEPPLPEDHQEEDDN 422
Query: 209 LQRQQQGQS 217
LQRQQQGQS
Sbjct: 423 LQRQQQGQS 431
Score = 75.1 bits (183), Expect = 4e-14
Identities = 43/80 (53%), Positives = 50/80 (62%), Gaps = 4/80 (5%)
Query: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVP--LPK--DSTGAADPPQPHIVGIQSP 56
MSWVQATLLARGLCRAWGGTCGAALTGTSISQVP LP+ + AA + +V
Sbjct: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE 60
Query: 57 DQQAALARHNPARPVFVEGP 76
+Q P +F + P
Sbjct: 61 PRQRPTKALVPFEDLFGQAP 80
>gi|215599065 evolutionarily conserved signaling intermediate in
Toll pathway isoform 2 [Homo sapiens]
Length = 296
Score = 75.1 bits (183), Expect = 4e-14
Identities = 43/80 (53%), Positives = 50/80 (62%), Gaps = 4/80 (5%)
Query: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVP--LPK--DSTGAADPPQPHIVGIQSP 56
MSWVQATLLARGLCRAWGGTCGAALTGTSISQVP LP+ + AA + +V
Sbjct: 1 MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPRRLPRGLHCSAAAHSSEQSLVPSPPE 60
Query: 57 DQQAALARHNPARPVFVEGP 76
+Q P +F + P
Sbjct: 61 PRQRPTKALVPFEDLFGQAP 80
Score = 50.1 bits (118), Expect = 1e-06
Identities = 22/24 (91%), Positives = 23/24 (95%)
Query: 29 SISQVPLPKDSTGAADPPQPHIVG 52
+I QVPLPKDSTGAADPPQPHIVG
Sbjct: 243 TIYQVPLPKDSTGAADPPQPHIVG 266
>gi|8922699 CNDP dipeptidase 2 [Homo sapiens]
Length = 475
Score = 30.4 bits (67), Expect = 1.2
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 4/84 (4%)
Query: 112 LYYPMQLDLEYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQGLQETNPTLA 171
+Y + + + GWD+ F + E +G ++ D+ +A WI L+ T
Sbjct: 96 IYGHLDVQPAALEDGWDSEPFTLVE-RDGKLYGG--GSTDDKGPVAGWINALEAYQKTGQ 152
Query: 172 QIPVVFRLAGSTRELQTSSAGLEE 195
+IPV R E ++ S GL+E
Sbjct: 153 EIPVNVRFCLEGME-ESGSEGLDE 175
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 391 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 426
>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
sapiens]
Length = 1004
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 903 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 938
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 723 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 758
>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
sapiens]
Length = 661
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 560 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 595
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 630 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 665
>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
sapiens]
Length = 644
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 543 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 578
>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
sapiens]
Length = 1100
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 999 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 1034
>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
sapiens]
Length = 666
Score = 30.0 bits (66), Expect = 1.6
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 37 KDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVF 72
K++ GA D P P I S D+ +L+ + P RPVF
Sbjct: 565 KNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVF 600
>gi|49087132 sal-like 2 [Homo sapiens]
Length = 1007
Score = 29.3 bits (64), Expect = 2.7
Identities = 14/33 (42%), Positives = 16/33 (48%)
Query: 16 AWGGTCGAALTGTSISQVPLPKDSTGAADPPQP 48
A GG G L + PLP +ST A PP P
Sbjct: 133 AAGGGGGLILASPKLGATPLPPESTPAPPPPPP 165
>gi|156938257 leucine rich repeat containing 16B [Homo sapiens]
Length = 1372
Score = 29.3 bits (64), Expect = 2.7
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 116 MQLDLEYVRSGWDNYEF---DINEVEEGPVFAMCMAGAHDQATMAKWIQGLQETNPTLAQ 172
+Q D++ + DN EF D + +E + M A A++Q + + L+ + L Q
Sbjct: 175 VQWDVDTIYHAEDNREFNLLDFSHLESRDLALMVAALAYNQWFTKLYCKDLRLGSEVLEQ 234
Query: 173 IPVVFRLAGSTRELQTSSAGLE 194
+ +GS EL +AGL+
Sbjct: 235 VLHTLSKSGSLEELVLDNAGLK 256
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 28.9 bits (63), Expect = 3.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Query: 181 GSTRELQTSSAGLEEPPLPEDHQEEDDNL 209
G L LEEPPL D +EEDD+L
Sbjct: 10 GGASPLPQVRVPLEEPPLSPDVEEEDDDL 38
>gi|157671953 solute carrier family 4, anion exchanger, member 3
isoform 2 [Homo sapiens]
Length = 1259
Score = 28.9 bits (63), Expect = 3.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Query: 181 GSTRELQTSSAGLEEPPLPEDHQEEDDNL 209
G L LEEPPL D +EEDD+L
Sbjct: 10 GGASPLPQVRVPLEEPPLSPDVEEEDDDL 38
>gi|62198237 DNA-directed DNA polymerase epsilon [Homo sapiens]
Length = 2286
Score = 28.5 bits (62), Expect = 4.6
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 121 EYVRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMA-KWIQGLQETNPTL 170
E V +++EF EGP C+ D+A + +W + +QET PT+
Sbjct: 311 EIVSEDIEDFEFTPKPEYEGP---FCVFNEPDEAHLIQRWFEHVQETKPTI 358
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 27.7 bits (60), Expect = 7.8
Identities = 21/61 (34%), Positives = 23/61 (37%), Gaps = 3/61 (4%)
Query: 16 AWGGTCGAALTGTSISQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARPVFVEG 75
A G GAA + P P +T A PP P P AA A PA P G
Sbjct: 55 AGGEGLGAAAAALLLHPPPPPPPATAAPPPPPP---PPPPPASAAAPASGPPAPPGLAAG 111
Query: 76 P 76
P
Sbjct: 112 P 112
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
sapiens]
Length = 532
Score = 27.7 bits (60), Expect = 7.8
Identities = 11/40 (27%), Positives = 21/40 (52%)
Query: 123 VRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQG 162
+R+ W N + ++E+E P +C +HD +A + G
Sbjct: 125 LRTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSG 164
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 27.7 bits (60), Expect = 7.8
Identities = 11/40 (27%), Positives = 21/40 (52%)
Query: 123 VRSGWDNYEFDINEVEEGPVFAMCMAGAHDQATMAKWIQG 162
+R+ W N + ++E+E P +C +HD +A + G
Sbjct: 191 LRTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSG 230
>gi|7662164 hypothetical protein LOC9764 [Homo sapiens]
Length = 411
Score = 27.7 bits (60), Expect = 7.8
Identities = 11/16 (68%), Positives = 12/16 (75%)
Query: 87 YYHILRADLLPPEERE 102
YYHI + LLPPE RE
Sbjct: 188 YYHIGKPQLLPPESRE 203
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,017,239
Number of Sequences: 37866
Number of extensions: 480146
Number of successful extensions: 1722
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1701
Number of HSP's gapped (non-prelim): 25
length of query: 217
length of database: 18,247,518
effective HSP length: 98
effective length of query: 119
effective length of database: 14,536,650
effective search space: 1729861350
effective search space used: 1729861350
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.