Guide to the Human Genome
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Search of human proteins with 215272376

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215272376 thioredoxin-like 4B [Homo sapiens]
         (149 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215272376 thioredoxin-like 4B [Homo sapiens]                       298   1e-81
gi|214832254 thioredoxin-like 4B [Homo sapiens]                       298   1e-81
gi|8923475 thioredoxin-like 4B [Homo sapiens]                         298   1e-81
gi|5729802 thioredoxin-like 4A [Homo sapiens]                         112   2e-25
gi|169164452 PREDICTED: similar to hCG1643669 [Homo sapiens]           73   1e-13
gi|169164815 PREDICTED: similar to hCG1643669 [Homo sapiens]           73   1e-13
gi|169163509 PREDICTED: hypothetical protein LOC100131482 [Homo ...    73   1e-13
gi|95113651 glutaredoxin 3 [Homo sapiens]                              39   0.002
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul...    30   0.98 
gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens]            30   0.98 
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]       28   3.7  
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]       28   3.7  
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]       28   3.7  
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]       28   3.7  
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]       28   3.7  
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]       28   3.7  
gi|24497453 nucleoporin 88kDa [Homo sapiens]                           28   3.7  
gi|28416925 purinergic receptor P2X3 [Homo sapiens]                    27   6.4  
gi|12408649 X-ray repair cross complementing protein 4 isoform 1...    27   8.3  
gi|4507945 X-ray repair cross complementing protein 4 isoform 1 ...    27   8.3  
gi|12408647 X-ray repair cross complementing protein 4 isoform 2...    27   8.3  

>gi|215272376 thioredoxin-like 4B [Homo sapiens]
          Length = 149

 Score =  298 bits (762), Expect = 1e-81
 Identities = 149/149 (100%), Positives = 149/149 (100%)

Query: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60
           MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL
Sbjct: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60

Query: 61  VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY 120
           VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY
Sbjct: 61  VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY 120

Query: 121 RGAMRGKLIVQSPIDPKNIPKYDLLYQDI 149
           RGAMRGKLIVQSPIDPKNIPKYDLLYQDI
Sbjct: 121 RGAMRGKLIVQSPIDPKNIPKYDLLYQDI 149


>gi|214832254 thioredoxin-like 4B [Homo sapiens]
          Length = 149

 Score =  298 bits (762), Expect = 1e-81
 Identities = 149/149 (100%), Positives = 149/149 (100%)

Query: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60
           MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL
Sbjct: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60

Query: 61  VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY 120
           VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY
Sbjct: 61  VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY 120

Query: 121 RGAMRGKLIVQSPIDPKNIPKYDLLYQDI 149
           RGAMRGKLIVQSPIDPKNIPKYDLLYQDI
Sbjct: 121 RGAMRGKLIVQSPIDPKNIPKYDLLYQDI 149


>gi|8923475 thioredoxin-like 4B [Homo sapiens]
          Length = 149

 Score =  298 bits (762), Expect = 1e-81
 Identities = 149/149 (100%), Positives = 149/149 (100%)

Query: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60
           MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL
Sbjct: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60

Query: 61  VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY 120
           VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY
Sbjct: 61  VDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIY 120

Query: 121 RGAMRGKLIVQSPIDPKNIPKYDLLYQDI 149
           RGAMRGKLIVQSPIDPKNIPKYDLLYQDI
Sbjct: 121 RGAMRGKLIVQSPIDPKNIPKYDLLYQDI 149


>gi|5729802 thioredoxin-like 4A [Homo sapiens]
          Length = 142

 Score =  112 bits (279), Expect = 2e-25
 Identities = 53/136 (38%), Positives = 90/136 (66%), Gaps = 2/136 (1%)

Query: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60
           MS++LP L +  +VDQAI S  ++V+V+RFG D DP C+++D++L   +  +   A IYL
Sbjct: 1   MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYL 60

Query: 61  VDVDQTAVYTQYFDISYIPSTV-FFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVI 119
           VD+ +   + + +++ Y P TV FFF  +H+ +D G+ ++ K   + + KQ+ +D+IE +
Sbjct: 61  VDITEVPDFNKMYEL-YDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETV 119

Query: 120 YRGAMRGKLIVQSPID 135
           YRGA +G+ +V SP D
Sbjct: 120 YRGARKGRGLVVSPKD 135


>gi|169164452 PREDICTED: similar to hCG1643669 [Homo sapiens]
          Length = 157

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 43/134 (32%), Positives = 75/134 (55%), Gaps = 3/134 (2%)

Query: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60
           MS +L  L S  +VDQAI    + + V+RFG   DP C+++D +L      +   A I+L
Sbjct: 1   MSHMLLHLHSSWQVDQAILPGEDCMAVIRFGHGWDPTCMKMDKVLYSIIEKVKDFAVIFL 60

Query: 61  VDVDQTAVYTQYFDISYIPSTV-FFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVI 119
           V++ +   + + +++ Y P T+ FFF  +H+ V  G+  + K   + + KQ+ +D+IE +
Sbjct: 61  VNITKVPDFNKMYEL-YDPCTIMFFFRNKHIMVVLGT-GNNKINWAMEDKQEMVDIIETV 118

Query: 120 YRGAMRGKLIVQSP 133
              A+ G  +V SP
Sbjct: 119 DCRALNGGDLVLSP 132


>gi|169164815 PREDICTED: similar to hCG1643669 [Homo sapiens]
          Length = 157

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 43/134 (32%), Positives = 75/134 (55%), Gaps = 3/134 (2%)

Query: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60
           MS +L  L S  +VDQAI    + + V+RFG   DP C+++D +L      +   A I+L
Sbjct: 1   MSHMLLHLHSSWQVDQAILPGEDCMAVIRFGHGWDPTCMKMDKVLYSIIEKVKDFAVIFL 60

Query: 61  VDVDQTAVYTQYFDISYIPSTV-FFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVI 119
           V++ +   + + +++ Y P T+ FFF  +H+ V  G+  + K   + + KQ+ +D+IE +
Sbjct: 61  VNITKVPDFNKMYEL-YDPCTIMFFFRNKHIMVVLGT-GNNKINWAMEDKQEMVDIIETV 118

Query: 120 YRGAMRGKLIVQSP 133
              A+ G  +V SP
Sbjct: 119 DCRALNGGDLVLSP 132


>gi|169163509 PREDICTED: hypothetical protein LOC100131482 [Homo
           sapiens]
          Length = 157

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 43/134 (32%), Positives = 75/134 (55%), Gaps = 3/134 (2%)

Query: 1   MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYL 60
           MS +L  L S  +VDQAI    + + V+RFG   DP C+++D +L      +   A I+L
Sbjct: 1   MSHMLLHLHSSWQVDQAILPGEDCMAVIRFGHGWDPTCMKMDKVLYSIIEKVKDFAVIFL 60

Query: 61  VDVDQTAVYTQYFDISYIPSTV-FFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVI 119
           V++ +   + + +++ Y P T+ FFF  +H+ V  G+  + K   + + KQ+ +D+IE +
Sbjct: 61  VNITKVPDFNKMYEL-YDPCTIMFFFRNKHIMVVLGT-GNNKINWAMEDKQEMVDIIETV 118

Query: 120 YRGAMRGKLIVQSP 133
              A+ G  +V SP
Sbjct: 119 DCRALNGGDLVLSP 132


>gi|95113651 glutaredoxin 3 [Homo sapiens]
          Length = 335

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 24/108 (22%), Positives = 59/108 (54%), Gaps = 7/108 (6%)

Query: 10  SKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVY 69
           S  + ++ ++  A+ +LV+ F     P C Q+++++++ + +L +++ + L + +     
Sbjct: 18  SAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKL-EAEGVPEV 76

Query: 70  TQYFDISYIPSTVFFFNGQHMKVD----YGSPDHTKFVGSFKTKQDFI 113
           ++ ++IS +P+ +FF N Q  K+D      +P+ TK V    +   F+
Sbjct: 77  SEKYEISSVPTFLFFKNSQ--KIDRLDGAHAPELTKKVQRHASSGSFL 122


>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
           [Homo sapiens]
          Length = 406

 Score = 29.6 bits (65), Expect = 0.98
 Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 29  RFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVYTQYFDISYIPSTVFFFNGQ 88
           RF +   P+  +  D++ +   + +++     VD DQ +   Q + IS  P+   F NG 
Sbjct: 59  RFSQMLHPIFEEASDVIKEEFPNENQVV-FARVDCDQHSDIAQRYRISKYPTLKLFRNGM 117

Query: 89  HMKVDYGSPDHTKFVGSFKTKQ 110
            MK +Y      K +  +  +Q
Sbjct: 118 MMKREYRGQRSVKALADYIRQQ 139


>gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens]
          Length = 1684

 Score = 29.6 bits (65), Expect = 0.98
 Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 16/103 (15%)

Query: 38  CLQLDDILSKTSSDLSKMAAIYLVDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSP 97
           CL+L D+  + + D +K + +YLV +     Y +++       + FFF  +  K  Y   
Sbjct: 270 CLKLGDLFFRVTDDRAKQSELYLVGM--ICYYGKHY-------STFFFQTKIRKWMYFDD 320

Query: 98  DHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIP 140
            H K +G       + D++    +G  +  L++ +  DP+  P
Sbjct: 321 AHVKEIG-----PKWKDVVTKCIKGHYQPLLLLYA--DPQGTP 356


>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
          Length = 2355

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 31   GRDEDPVCLQLDDILSKTSSDLSKMAAI---YLVDVDQTAVYTQYFDISY 77
            GR+E P+ +     +S    DL  +AA     L+  D  AV  +Y+ I+Y
Sbjct: 1433 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1482


>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
          Length = 2477

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 31   GRDEDPVCLQLDDILSKTSSDLSKMAAI---YLVDVDQTAVYTQYFDISY 77
            GR+E P+ +     +S    DL  +AA     L+  D  AV  +Y+ I+Y
Sbjct: 1524 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573


>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 31   GRDEDPVCLQLDDILSKTSSDLSKMAAI---YLVDVDQTAVYTQYFDISY 77
            GR+E P+ +     +S    DL  +AA     L+  D  AV  +Y+ I+Y
Sbjct: 1433 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1482


>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
          Length = 2296

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 31   GRDEDPVCLQLDDILSKTSSDLSKMAAI---YLVDVDQTAVYTQYFDISY 77
            GR+E P+ +     +S    DL  +AA     L+  D  AV  +Y+ I+Y
Sbjct: 1433 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1482


>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 31   GRDEDPVCLQLDDILSKTSSDLSKMAAI---YLVDVDQTAVYTQYFDISY 77
            GR+E P+ +     +S    DL  +AA     L+  D  AV  +Y+ I+Y
Sbjct: 1524 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573


>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
          Length = 2176

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 31   GRDEDPVCLQLDDILSKTSSDLSKMAAI---YLVDVDQTAVYTQYFDISY 77
            GR+E P+ +     +S    DL  +AA     L+  D  AV  +Y+ I+Y
Sbjct: 1433 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1482


>gi|24497453 nucleoporin 88kDa [Homo sapiens]
          Length = 741

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 59  YLVDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEV 118
           Y   + +TAV   +  ++ +P T+F  NG+   V Y           ++  + F+  I +
Sbjct: 230 YTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAY------PLYILYENGETFLTYISL 283

Query: 119 IYRGAMRGKLIVQSPIDP 136
           ++     GKL+   P+ P
Sbjct: 284 LHSPGNIGKLLGPLPMHP 301


>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
          Length = 397

 Score = 26.9 bits (58), Expect = 6.4
 Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query: 21  TAEKVLVLRFGRDEDPVC--LQLDDILSKTSSDLSKMA 56
           TA  +   RF  D+DP C  L++ D++     D +K+A
Sbjct: 196 TARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLA 233


>gi|12408649 X-ray repair cross complementing protein 4 isoform 1
           [Homo sapiens]
          Length = 334

 Score = 26.6 bits (57), Expect = 8.3
 Identities = 15/50 (30%), Positives = 25/50 (50%)

Query: 8   LTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAA 57
           L + +E ++ IK   E  +      D DPV  +  D  S+  +DLS +A+
Sbjct: 199 LNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLAS 248


>gi|4507945 X-ray repair cross complementing protein 4 isoform 1
           [Homo sapiens]
          Length = 334

 Score = 26.6 bits (57), Expect = 8.3
 Identities = 15/50 (30%), Positives = 25/50 (50%)

Query: 8   LTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAA 57
           L + +E ++ IK   E  +      D DPV  +  D  S+  +DLS +A+
Sbjct: 199 LNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLAS 248


>gi|12408647 X-ray repair cross complementing protein 4 isoform 2
           [Homo sapiens]
          Length = 336

 Score = 26.6 bits (57), Expect = 8.3
 Identities = 15/50 (30%), Positives = 25/50 (50%)

Query: 8   LTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAA 57
           L + +E ++ IK   E  +      D DPV  +  D  S+  +DLS +A+
Sbjct: 199 LNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLAS 248


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,850,115
Number of Sequences: 37866
Number of extensions: 181042
Number of successful extensions: 374
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 360
Number of HSP's gapped (non-prelim): 21
length of query: 149
length of database: 18,247,518
effective HSP length: 93
effective length of query: 56
effective length of database: 14,725,980
effective search space: 824654880
effective search space used: 824654880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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