Guide to the Human Genome
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Search of human proteins with 215272347

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase
2 isoform b [Homo sapiens]
         (466 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...   968   0.0  
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2...   913   0.0  
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ...   913   0.0  
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i...   224   1e-58
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ...   224   1e-58
gi|27765093 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ...   117   2e-26
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]              70   4e-12
gi|13569938 sialyltransferase 7E [Homo sapiens]                        68   2e-11
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [...    66   6e-11
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H...    66   6e-11
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]                66   8e-11
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]               65   1e-10
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]               65   1e-10
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]               65   1e-10
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]               65   1e-10
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]               65   1e-10
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]               65   1e-10
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]                65   1e-10
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]             62   8e-10
gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]             62   8e-10
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H...    59   7e-09
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    59   1e-08
gi|21361444 sialytransferase 7F [Homo sapiens]                         58   2e-08
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...    57   5e-08
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ...    57   5e-08
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H...    56   6e-08
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran...    55   1e-07
gi|21264332 sialyltransferase 7A [Homo sapiens]                        55   1e-07
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]              55   1e-07
gi|5031999 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf...    53   7e-07

>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform b [Homo sapiens]
          Length = 466

 Score =  968 bits (2503), Expect = 0.0
 Identities = 466/466 (100%), Positives = 466/466 (100%)

Query: 1   MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
           MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA
Sbjct: 1   MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60

Query: 61  IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
           IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS
Sbjct: 61  IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120

Query: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
           QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ
Sbjct: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180

Query: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
           RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG
Sbjct: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240

Query: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
           KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM
Sbjct: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300

Query: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
           SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS
Sbjct: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360

Query: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
           LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420

Query: 421 IQENTKEKIQPNPPSSGFIGSFVKIGHIRACSEPRSRDCTPAWTTE 466
           IQENTKEKIQPNPPSSGFIGSFVKIGHIRACSEPRSRDCTPAWTTE
Sbjct: 421 IQENTKEKIQPNPPSSGFIGSFVKIGHIRACSEPRSRDCTPAWTTE 466


>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score =  913 bits (2360), Expect = 0.0
 Identities = 441/449 (98%), Positives = 443/449 (98%)

Query: 1   MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
           MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA
Sbjct: 1   MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60

Query: 61  IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
           IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS
Sbjct: 61  IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120

Query: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
           QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ
Sbjct: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180

Query: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
           RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG
Sbjct: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240

Query: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
           KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM
Sbjct: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300

Query: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
           SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS
Sbjct: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360

Query: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
           LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420

Query: 421 IQENTKEKIQPNPPSSGFIGSFVKIGHIR 449
           IQENTKEKIQPNPPSSGFIG  + +   R
Sbjct: 421 IQENTKEKIQPNPPSSGFIGILIMMSMCR 449


>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
           isoform a [Homo sapiens]
          Length = 529

 Score =  913 bits (2360), Expect = 0.0
 Identities = 441/449 (98%), Positives = 443/449 (98%)

Query: 1   MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
           MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA
Sbjct: 1   MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60

Query: 61  IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
           IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS
Sbjct: 61  IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120

Query: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
           QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ
Sbjct: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180

Query: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
           RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG
Sbjct: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240

Query: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
           KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM
Sbjct: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300

Query: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
           SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS
Sbjct: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360

Query: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
           LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420

Query: 421 IQENTKEKIQPNPPSSGFIGSFVKIGHIR 449
           IQENTKEKIQPNPPSSGFIG  + +   R
Sbjct: 421 IQENTKEKIQPNPPSSGFIGILIMMSMCR 449


>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score =  224 bits (572), Expect = 1e-58
 Identities = 112/241 (46%), Positives = 157/241 (65%), Gaps = 5/241 (2%)

Query: 205 YRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRGKREA-GLSRAQLLCQLRSRARVRT 263
           +++W  + SSK L PRLQK  K+YL+ NK+ V ++G       S   L C LR    V  
Sbjct: 93  FQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSM 152

Query: 264 LDGTEAPFSALGWRRLVPAVPL-SQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLR 322
           ++ T+ PF+   W   +P   + ++  P G   CAVV SAG++ +S LG EID HDAVLR
Sbjct: 153 VEVTDFPFNTSEWEGYLPKESIRTKAGPWG--RCAVVSSAGSLKSSQLGREIDDHDAVLR 210

Query: 323 FNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLW 382
           FN APT  +++DVG KTTIR++NSQ++T     F+  SLY + IL+ WDP+ Y +++  W
Sbjct: 211 FNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR-FLKDSLYNEGILIVWDPSVYHSDIPKW 269

Query: 383 YKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGSF 442
           Y+ PDYN F  Y  +R+ +PNQPFYIL P+  W+LWDI+QE + E+IQPNPPSSG +G  
Sbjct: 270 YQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGII 329

Query: 443 V 443
           +
Sbjct: 330 I 330


>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform a [Homo sapiens]
          Length = 406

 Score =  224 bits (572), Expect = 1e-58
 Identities = 112/241 (46%), Positives = 157/241 (65%), Gaps = 5/241 (2%)

Query: 205 YRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRGKREA-GLSRAQLLCQLRSRARVRT 263
           +++W  + SSK L PRLQK  K+YL+ NK+ V ++G       S   L C LR    V  
Sbjct: 93  FQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSM 152

Query: 264 LDGTEAPFSALGWRRLVPAVPL-SQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLR 322
           ++ T+ PF+   W   +P   + ++  P G   CAVV SAG++ +S LG EID HDAVLR
Sbjct: 153 VEVTDFPFNTSEWEGYLPKESIRTKAGPWG--RCAVVSSAGSLKSSQLGREIDDHDAVLR 210

Query: 323 FNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLW 382
           FN APT  +++DVG KTTIR++NSQ++T     F+  SLY + IL+ WDP+ Y +++  W
Sbjct: 211 FNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR-FLKDSLYNEGILIVWDPSVYHSDIPKW 269

Query: 383 YKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGSF 442
           Y+ PDYN F  Y  +R+ +PNQPFYIL P+  W+LWDI+QE + E+IQPNPPSSG +G  
Sbjct: 270 YQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGII 329

Query: 443 V 443
           +
Sbjct: 330 I 330


>gi|27765093 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
           isoform b [Homo sapiens]
          Length = 175

 Score =  117 bits (293), Expect = 2e-26
 Identities = 50/100 (50%), Positives = 71/100 (71%), Gaps = 1/100 (1%)

Query: 344 INSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPN 403
           +NSQ++T     F+  SLY + IL+ WDP+ Y +++  WY+ PDYN F  Y  +R+ +PN
Sbjct: 1   MNSQLVTTEKR-FLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPN 59

Query: 404 QPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGSFV 443
           QPFYIL P+  W+LWDI+QE + E+IQPNPPSSG +G  +
Sbjct: 60  QPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIII 99


>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
          Length = 302

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 36/81 (44%), Positives = 52/81 (64%), Gaps = 7/81 (8%)

Query: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----IL 349
           RSCAVV S+G +L S LG EIDS + V R N APT G+E DVG ++T+R+++      +L
Sbjct: 74  RSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLL 133

Query: 350 TNPSHHFIDSSLYKDVILVAW 370
            N SH+F  +   +D + + W
Sbjct: 134 RNYSHYFQKA---RDTLYMVW 151


>gi|13569938 sialyltransferase 7E [Homo sapiens]
          Length = 336

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 33/85 (38%), Positives = 53/85 (62%), Gaps = 5/85 (5%)

Query: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRII---NSQILT 350
           R CA+V S+G +L+S  G +ID  + V+R N APTRGY +DVGN+T++R+I   + Q + 
Sbjct: 94  RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRIL 153

Query: 351 NPSHHFIDSSLYKDVILVAWDPAPY 375
              H  ++ S  +  + + W P+ Y
Sbjct: 154 RNRHDLLNVS--QGTVFIFWGPSSY 176


>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
           [Homo sapiens]
          Length = 340

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 35/69 (50%), Positives = 44/69 (63%), Gaps = 2/69 (2%)

Query: 278 RLVPAV--PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
           R+VP    P+ +    G R CAVV ++G +  SS G EIDSHD VLR N APT G+E DV
Sbjct: 122 RVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADV 181

Query: 336 GNKTTIRII 344
           G KTT  ++
Sbjct: 182 GTKTTHHLV 190


>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
           sapiens]
          Length = 340

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 35/69 (50%), Positives = 44/69 (63%), Gaps = 2/69 (2%)

Query: 278 RLVPAV--PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
           R+VP    P+ +    G R CAVV ++G +  SS G EIDSHD VLR N APT G+E DV
Sbjct: 122 RVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADV 181

Query: 336 GNKTTIRII 344
           G KTT  ++
Sbjct: 182 GTKTTHHLV 190


>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
          Length = 331

 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 49/162 (30%), Positives = 81/162 (50%), Gaps = 31/162 (19%)

Query: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ-ILTNP 352
           + C VV + G + N +LGE+IDS+D ++R N+ P  G+E++VG +TT R+   + + ++P
Sbjct: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDP 175

Query: 353 SHHFIDSSLYKDVILVAWDPAPY----------SANLNLWYKKPDYNLFTPYIQHRQRNP 402
            H+  +++    VIL A+ P               N N ++KKP  NL     Q R  +P
Sbjct: 176 IHNDPNTT----VILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDP 231

Query: 403 ----NQPFYILH-PKFIWQLWDIIQENTKEKIQPNPPSSGFI 439
                  + +LH PK       +  +N K    P  P++G I
Sbjct: 232 FIIRTAAYELLHFPK-------VFPKNQK----PKHPTTGII 262


>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
          Length = 413

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 185 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 239

Query: 338 KTTIRI 343
           KTT+RI
Sbjct: 240 KTTLRI 245


>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
          Length = 359

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 131 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 185

Query: 338 KTTIRI 343
           KTT+RI
Sbjct: 186 KTTLRI 191


>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
          Length = 429

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 201 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 255

Query: 338 KTTIRI 343
           KTT+RI
Sbjct: 256 KTTLRI 261


>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
          Length = 277

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 147 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 201

Query: 338 KTTIRI 343
           KTT+RI
Sbjct: 202 KTTLRI 207


>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
          Length = 390

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 162 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 216

Query: 338 KTTIRI 343
           KTT+RI
Sbjct: 217 KTTLRI 222


>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
          Length = 444

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 216 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 270

Query: 338 KTTIRI 343
           KTT+RI
Sbjct: 271 KTTLRI 276


>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
          Length = 375

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)

Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
           RL PA     L     R C +V + G + N SLG  ID +D V+R NSAP +G+EKDVG+
Sbjct: 147 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 201

Query: 338 KTTIRI 343
           KTT+RI
Sbjct: 202 KTTLRI 207


>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
          Length = 305

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 7/81 (8%)

Query: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTN 351
           CA+V ++G ++   +G EID    + R N+APT+GYE+DVG  T IR+++      +L N
Sbjct: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139

Query: 352 PSHHFIDSSLYKDVILVAWDP 372
           P + F +++     I V W P
Sbjct: 140 PDYFFKEAN---TTIYVIWGP 157


>gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]
          Length = 210

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 7/81 (8%)

Query: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTN 351
           CA+V ++G ++   +G EID    + R N+APT+GYE+DVG  T IR+++      +L N
Sbjct: 80  CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139

Query: 352 PSHHFIDSSLYKDVILVAWDP 372
           P + F +++     I V W P
Sbjct: 140 PDYFFKEAN---TTIYVIWGP 157


>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
           sapiens]
          Length = 329

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 36/91 (39%), Positives = 53/91 (58%), Gaps = 9/91 (9%)

Query: 261 VRTLDGTEAPFSALGWRRL---VPAVPLSQLHPRGLRS-----CAVVMSAGAILNSSLGE 312
           V+T    E P+   G   L   V A+  S + P+ ++S     C VV +   + NSSLG+
Sbjct: 74  VKTPSAYELPYGTKGSEDLLLRVLAITSSSI-PKNIQSLRCRRCVVVGNGHRLRNSSLGD 132

Query: 313 EIDSHDAVLRFNSAPTRGYEKDVGNKTTIRI 343
            I+ +D V+R N+AP  GYE DVG+KTT+R+
Sbjct: 133 AINKYDVVIRLNNAPVAGYEGDVGSKTTMRL 163


>gi|5174677 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 2 [Homo sapiens]
          Length = 375

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 48/197 (24%), Positives = 87/197 (44%), Gaps = 23/197 (11%)

Query: 170 RRRVKKRHRRQRRSHVLEEGDDGDRLYSSMSRAFLYRL------WKGNVSSKMLNPRLQK 223
           R  V   H +  R+ V+  G     +    + +  + +      W+ N   + L+ R++K
Sbjct: 42  RSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHN---QTLSLRIRK 98

Query: 224 AMKDYLTANKHGVRFRGKREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAV 283
            +  +L A K     +G  + G     ++  +  R      D T      L +  L    
Sbjct: 99  QILKFLDAEKDISVLKGTLKPG----DIIHYIFDR------DSTMNVSQNL-YELLPRTS 147

Query: 284 PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRI 343
           PL   H     +CA+V ++G +LNS  G+EID+H  V+R N AP + Y +DVG KT +  
Sbjct: 148 PLKNKH---FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVT 204

Query: 344 INSQILTNPSHHFIDSS 360
           +N  ++       ++++
Sbjct: 205 MNPSVIQRAFEDLVNAT 221


>gi|21361444 sialytransferase 7F [Homo sapiens]
          Length = 333

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 14/140 (10%)

Query: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINS--- 346
           P     C +V S+  +L + LG EI+  +  +R N APT GY  DVGNKTT R++     
Sbjct: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSV 161

Query: 347 -QILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQP 405
            ++L  P   F++ +   + + + W P           +KP  +L     +     PN  
Sbjct: 162 FRVLRRP-QEFVNRT--PETVFIFWGPPSK-------MQKPQGSLVRVIQRAGLVFPNME 211

Query: 406 FYILHPKFIWQLWDIIQENT 425
            Y + P  + Q  D+ +  T
Sbjct: 212 AYAVSPGRMRQFDDLFRGET 231


>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 2 [Homo sapiens]
          Length = 395

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 50/166 (30%), Positives = 72/166 (43%), Gaps = 32/166 (19%)

Query: 288 LHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ 347
           L  +  R C V+ S G +    LG  ++  D V+R NSAP  GY + VGNKTTIR+   +
Sbjct: 164 LKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPE 223

Query: 348 -----ILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYNLFTPYIQ 396
                 L   S+    + L+K V       +V  +  P+   L  W             Q
Sbjct: 224 GAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWK------------Q 271

Query: 397 HRQRNPNQP--FYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIG 440
             ++ P QP  F IL+P        II+E   + +Q + P S F G
Sbjct: 272 VAEKIPLQPKHFRILNPV-------IIKETAFDILQYSEPQSRFWG 310


>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
           isoform 1 [Homo sapiens]
          Length = 418

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 50/166 (30%), Positives = 72/166 (43%), Gaps = 32/166 (19%)

Query: 288 LHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ 347
           L  +  R C V+ S G +    LG  ++  D V+R NSAP  GY + VGNKTTIR+   +
Sbjct: 187 LKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPE 246

Query: 348 -----ILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYNLFTPYIQ 396
                 L   S+    + L+K V       +V  +  P+   L  W             Q
Sbjct: 247 GAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWK------------Q 294

Query: 397 HRQRNPNQP--FYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIG 440
             ++ P QP  F IL+P        II+E   + +Q + P S F G
Sbjct: 295 VAEKIPLQPKHFRILNPV-------IIKETAFDILQYSEPQSRFWG 333


>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
           sapiens]
          Length = 350

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 23/51 (45%), Positives = 36/51 (70%)

Query: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTT 340
           P   R CAVV ++G +  S  G+++D H+ ++R N APT G+E+DVG++TT
Sbjct: 146 PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTT 196


>gi|110815855 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 3 [Homo sapiens]
          Length = 380

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 30/74 (40%), Positives = 42/74 (56%), Gaps = 2/74 (2%)

Query: 276 WRRLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
           +R L+P V  S +  +    CAVV ++G +  S  G+EID  D V R N APT  +++DV
Sbjct: 144 FRSLLPDV--SPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDV 201

Query: 336 GNKTTIRIINSQIL 349
           G KT +   N  IL
Sbjct: 202 GRKTNLTTFNPSIL 215


>gi|21264332 sialyltransferase 7A [Homo sapiens]
          Length = 600

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 33/67 (49%), Positives = 43/67 (64%), Gaps = 7/67 (10%)

Query: 281 PAVPLSQLH----PRG-LR--SCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEK 333
           P VP  QL     P G LR  +CAVV + G + NS +G+EIDSHD V R + A  +GYE+
Sbjct: 343 PPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQ 402

Query: 334 DVGNKTT 340
           DVG +T+
Sbjct: 403 DVGTRTS 409


>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
          Length = 218

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 7/70 (10%)

Query: 305 ILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTNPSHHFIDSS 360
           +L S LG EIDS + V R N APT G+E DVG ++T+R+++      +L N SH+F  + 
Sbjct: 1   MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKA- 59

Query: 361 LYKDVILVAW 370
             +D + + W
Sbjct: 60  --RDTLYMVW 67


>gi|5031999 ST8 alpha-N-acetyl-neuraminide
           alpha-2,8-sialyltransferase 4 isoform a [Homo sapiens]
          Length = 359

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 28/71 (39%), Positives = 44/71 (61%), Gaps = 2/71 (2%)

Query: 279 LVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNK 338
           L+P V  S +  R  ++CAVV ++G +L+S  G+EIDSH+ V+R N AP   +  DVG K
Sbjct: 127 LLPEV--SPMKNRRFKTCAVVGNSGILLDSECGKEIDSHNFVIRCNLAPVVEFAADVGTK 184

Query: 339 TTIRIINSQIL 349
           +    +N  ++
Sbjct: 185 SDFITMNPSVV 195


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,821,488
Number of Sequences: 37866
Number of extensions: 1071041
Number of successful extensions: 3183
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 3133
Number of HSP's gapped (non-prelim): 54
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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