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Search of human proteins with 215272345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase
2 isoform a [Homo sapiens]
(529 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 1100 0.0
gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 ... 1100 0.0
gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2... 913 0.0
gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 i... 330 3e-90
gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 330 3e-90
gi|27765093 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 ... 222 6e-58
gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens] 82 1e-15
gi|13569938 sialyltransferase 7E [Homo sapiens] 78 2e-14
gi|28373092 sialyltransferase 7D isoform a [Homo sapiens] 75 1e-13
gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [... 73 6e-13
gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [H... 73 6e-13
gi|21361444 sialytransferase 7F [Homo sapiens] 72 1e-12
gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [H... 71 2e-12
gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens] 71 3e-12
gi|28373086 sialyltransferase 6 isoform i [Homo sapiens] 69 8e-12
gi|28373082 sialyltransferase 6 isoform g [Homo sapiens] 69 8e-12
gi|28373078 sialyltransferase 6 isoform f [Homo sapiens] 69 8e-12
gi|28373070 sialyltransferase 6 isoform b [Homo sapiens] 69 8e-12
gi|28373068 sialyltransferase 6 isoform a [Homo sapiens] 69 8e-12
gi|5454060 sialyltransferase 6 isoform j [Homo sapiens] 69 8e-12
gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 67 5e-11
gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ... 67 5e-11
gi|28373074 sialyltransferase 6 isoform d [Homo sapiens] 65 2e-10
gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens] 62 1e-09
gi|110815855 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltran... 62 1e-09
gi|5174677 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransf... 62 1e-09
gi|21264332 sialyltransferase 7A [Homo sapiens] 62 2e-09
gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [H... 62 2e-09
gi|28373094 sialyltransferase 7D isoform b [Homo sapiens] 60 5e-09
gi|54234057 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltrans... 59 1e-08
>gi|215272345 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 1100 bits (2844), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA
Sbjct: 1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
Query: 61 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS
Sbjct: 61 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
Query: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ
Sbjct: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
Query: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG
Sbjct: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
Query: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM
Sbjct: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
Query: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS
Sbjct: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
Query: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
Query: 421 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 480
IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG
Sbjct: 421 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 480
Query: 481 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 529
AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS
Sbjct: 481 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 529
>gi|26190610 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform a [Homo sapiens]
Length = 529
Score = 1100 bits (2844), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA
Sbjct: 1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
Query: 61 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS
Sbjct: 61 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
Query: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ
Sbjct: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
Query: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG
Sbjct: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
Query: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM
Sbjct: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
Query: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS
Sbjct: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
Query: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
Query: 421 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 480
IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG
Sbjct: 421 IQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLG 480
Query: 481 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 529
AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS
Sbjct: 481 AYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS 529
>gi|215272347 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
isoform b [Homo sapiens]
Length = 466
Score = 913 bits (2360), Expect = 0.0
Identities = 441/449 (98%), Positives = 443/449 (98%)
Query: 1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA
Sbjct: 1 MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRA 60
Query: 61 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS
Sbjct: 61 IMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKS 120
Query: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ
Sbjct: 121 QSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQ 180
Query: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG
Sbjct: 181 RRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRG 240
Query: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM
Sbjct: 241 KREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVM 300
Query: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS
Sbjct: 301 SAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSS 360
Query: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI
Sbjct: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
Query: 421 IQENTKEKIQPNPPSSGFIGILIMMSMCR 449
IQENTKEKIQPNPPSSGFIG + + R
Sbjct: 421 IQENTKEKIQPNPPSSGFIGSFVKIGHIR 449
>gi|4506949 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 330 bits (845), Expect = 3e-90
Identities = 155/317 (48%), Positives = 221/317 (69%), Gaps = 5/317 (1%)
Query: 205 YRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRGKREA-GLSRAQLLCQLRSRARVRT 263
+++W + SSK L PRLQK K+YL+ NK+ V ++G S L C LR V
Sbjct: 93 FQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSM 152
Query: 264 LDGTEAPFSALGWRRLVPAVPL-SQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLR 322
++ T+ PF+ W +P + ++ P G CAVV SAG++ +S LG EID HDAVLR
Sbjct: 153 VEVTDFPFNTSEWEGYLPKESIRTKAGPWG--RCAVVSSAGSLKSSQLGREIDDHDAVLR 210
Query: 323 FNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLW 382
FN APT +++DVG KTTIR++NSQ++T F+ SLY + IL+ WDP+ Y +++ W
Sbjct: 211 FNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR-FLKDSLYNEGILIVWDPSVYHSDIPKW 269
Query: 383 YKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGIL 442
Y+ PDYN F Y +R+ +PNQPFYIL P+ W+LWDI+QE + E+IQPNPPSSG +GI+
Sbjct: 270 YQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGII 329
Query: 443 IMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGD 502
IMM++C +V +YE++PS R+T++C+Y++ ++D+ACT+GAYHPLLYEK LV+ LN GT D
Sbjct: 330 IMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDED 389
Query: 503 LHRKGKVVLPGFQAVHC 519
++ GK LPGF+ +HC
Sbjct: 390 IYLLGKATLPGFRTIHC 406
>gi|27765091 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform a [Homo sapiens]
Length = 406
Score = 330 bits (845), Expect = 3e-90
Identities = 155/317 (48%), Positives = 221/317 (69%), Gaps = 5/317 (1%)
Query: 205 YRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRGKREA-GLSRAQLLCQLRSRARVRT 263
+++W + SSK L PRLQK K+YL+ NK+ V ++G S L C LR V
Sbjct: 93 FQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSM 152
Query: 264 LDGTEAPFSALGWRRLVPAVPL-SQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLR 322
++ T+ PF+ W +P + ++ P G CAVV SAG++ +S LG EID HDAVLR
Sbjct: 153 VEVTDFPFNTSEWEGYLPKESIRTKAGPWG--RCAVVSSAGSLKSSQLGREIDDHDAVLR 210
Query: 323 FNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLW 382
FN APT +++DVG KTTIR++NSQ++T F+ SLY + IL+ WDP+ Y +++ W
Sbjct: 211 FNGAPTANFQQDVGTKTTIRLMNSQLVTTEKR-FLKDSLYNEGILIVWDPSVYHSDIPKW 269
Query: 383 YKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGIL 442
Y+ PDYN F Y +R+ +PNQPFYIL P+ W+LWDI+QE + E+IQPNPPSSG +GI+
Sbjct: 270 YQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGII 329
Query: 443 IMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGD 502
IMM++C +V +YE++PS R+T++C+Y++ ++D+ACT+GAYHPLLYEK LV+ LN GT D
Sbjct: 330 IMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDED 389
Query: 503 LHRKGKVVLPGFQAVHC 519
++ GK LPGF+ +HC
Sbjct: 390 IYLLGKATLPGFRTIHC 406
>gi|27765093 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
isoform b [Homo sapiens]
Length = 175
Score = 222 bits (566), Expect = 6e-58
Identities = 93/176 (52%), Positives = 135/176 (76%), Gaps = 1/176 (0%)
Query: 344 INSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPN 403
+NSQ++T F+ SLY + IL+ WDP+ Y +++ WY+ PDYN F Y +R+ +PN
Sbjct: 1 MNSQLVTTEKR-FLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPN 59
Query: 404 QPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQT 463
QPFYIL P+ W+LWDI+QE + E+IQPNPPSSG +GI+IMM++C +V +YE++PS R+T
Sbjct: 60 QPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKT 119
Query: 464 ELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHC 519
++C+Y++ ++D+ACT+GAYHPLLYEK LV+ LN GT D++ GK LPGF+ +HC
Sbjct: 120 DVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC 175
>gi|5174697 alpha2,3-sialyltransferase VI [Homo sapiens]
Length = 331
Score = 82.0 bits (201), Expect = 1e-15
Identities = 64/218 (29%), Positives = 109/218 (50%), Gaps = 34/218 (15%)
Query: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ-ILTNP 352
+ C VV + G + N +LGE+IDS+D ++R N+ P G+E++VG +TT R+ + + ++P
Sbjct: 116 KKCVVVGNGGVLKNKTLGEKIDSYDVIIRMNNGPVLGHEEEVGRRTTFRLFYPESVFSDP 175
Query: 353 SHHFIDSSLYKDVILVAWDPAPY----------SANLNLWYKKPDYNLFTPYIQHRQRNP 402
H+ +++ VIL A+ P N N ++KKP NL Q R +P
Sbjct: 176 IHNDPNTT----VILTAFKPHDLRWLLELLMGDKINTNGFWKKPALNLIYKPYQIRILDP 231
Query: 403 ----NQPFYILH-PKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHV--YE 455
+ +LH PK + +N K P P++G I I + +C EVH+ ++
Sbjct: 232 FIIRTAAYELLHFPK-------VFPKNQK----PKHPTTGIIAITLAFYICHEVHLAGFK 280
Query: 456 YIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQ 493
Y S ++ L HY+ + AYH + E+L ++
Sbjct: 281 YNFSDLKSPL-HYYGNATMSLMNKNAYHNVTAEQLFLK 317
>gi|13569938 sialyltransferase 7E [Homo sapiens]
Length = 336
Score = 78.2 bits (191), Expect = 2e-14
Identities = 63/256 (24%), Positives = 116/256 (45%), Gaps = 38/256 (14%)
Query: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRII---NSQILT 350
R CA+V S+G +L+S G +ID + V+R N APTRGY +DVGN+T++R+I + Q +
Sbjct: 94 RDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRIL 153
Query: 351 NPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILH 410
H ++ S + + + W P+ Y + +L + + P +++
Sbjct: 154 RNRHDLLNVS--QGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVL------PRLKAFMIT 205
Query: 411 PKFIWQLWDIIQENT--KEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELC-- 466
+ Q ++ ++ T KI S+G+ + I + +C ++VY +P + C
Sbjct: 206 RHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVP----PDFCRD 261
Query: 467 --------HYHELYYDAACTL---------GAYHPLLYEKLLVQRLNMGTQGDLHRKGKV 509
HY+E + CT+ G++H + EK + + N ++H
Sbjct: 262 PNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITEKRVFK--NWARTFNIHFFQPD 319
Query: 510 VLPGFQAVHCPAPSPV 525
P A++ P PV
Sbjct: 320 WKPESLAINHPENKPV 335
>gi|28373092 sialyltransferase 7D isoform a [Homo sapiens]
Length = 302
Score = 75.1 bits (183), Expect = 1e-13
Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 15/180 (8%)
Query: 294 RSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----IL 349
RSCAVV S+G +L S LG EIDS + V R N APT G+E DVG ++T+R+++ +L
Sbjct: 74 RSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLL 133
Query: 350 TNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYIL 409
N SH+F + +D + + W + + + +Q + P Y
Sbjct: 134 RNYSHYFQKA---RDTLYMVWGQGRHMDRV------LGGRTYRTLLQLTRMYPGLQVYTF 184
Query: 410 HPKFIWQLWDIIQENTKEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIPSVRQTELCH 467
+ + I Q+ T + + + S+G+ +++ + +C E+ VY + E H
Sbjct: 185 TERMMAYCDQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSH 244
>gi|27765096 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
[Homo sapiens]
Length = 340
Score = 73.2 bits (178), Expect = 6e-13
Identities = 56/187 (29%), Positives = 85/187 (45%), Gaps = 27/187 (14%)
Query: 278 RLVPAV--PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
R+VP P+ + G R CAVV ++G + SS G EIDSHD VLR N APT G+E DV
Sbjct: 122 RVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADV 181
Query: 336 GNKTTIRIINSQILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYN 389
G KTT HH + ++++ ILV + ++ +
Sbjct: 182 GTKTT-------------HHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISH 228
Query: 390 LFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCR 449
+ P + + R I HP FI ++D + PS+G + ++ M +C
Sbjct: 229 TYIP-VPAKIRVKQDKILIYHPAFIKYVFDNWLQG-----HGRYPSTGILSVIFSMHVCD 282
Query: 450 EVHVYEY 456
EV +Y +
Sbjct: 283 EVDLYGF 289
>gi|4506951 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 [Homo
sapiens]
Length = 340
Score = 73.2 bits (178), Expect = 6e-13
Identities = 56/187 (29%), Positives = 85/187 (45%), Gaps = 27/187 (14%)
Query: 278 RLVPAV--PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
R+VP P+ + G R CAVV ++G + SS G EIDSHD VLR N APT G+E DV
Sbjct: 122 RVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADV 181
Query: 336 GNKTTIRIINSQILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYN 389
G KTT HH + ++++ ILV + ++ +
Sbjct: 182 GTKTT-------------HHLVYPESFRELGDNVSMILVPFKTIDLEWVVSAITTGTISH 228
Query: 390 LFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCR 449
+ P + + R I HP FI ++D + PS+G + ++ M +C
Sbjct: 229 TYIP-VPAKIRVKQDKILIYHPAFIKYVFDNWLQG-----HGRYPSTGILSVIFSMHVCD 282
Query: 450 EVHVYEY 456
EV +Y +
Sbjct: 283 EVDLYGF 289
>gi|21361444 sialytransferase 7F [Homo sapiens]
Length = 333
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 16/175 (9%)
Query: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINS--- 346
P C +V S+ +L + LG EI+ + +R N APT GY DVGNKTT R++
Sbjct: 102 PSRCHQCVIVSSSSHLLGTKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSV 161
Query: 347 -QILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQP 405
++L P F++ + + + + W P +KP +L + PN
Sbjct: 162 FRVLRRP-QEFVNRT--PETVFIFWGPPSK-------MQKPQGSLVRVIQRAGLVFPNME 211
Query: 406 FYILHPKFIWQLWDIIQENTKEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIP 458
Y + P + Q D+ + T + + + S+G+ ++I + +C VHVY +P
Sbjct: 212 AYAVSPGRMRQFDDLFRGETGKDREKSHSWLSTGWFTMVIAVELCDHVHVYGMVP 266
>gi|5454058 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Homo
sapiens]
Length = 329
Score = 71.2 bits (173), Expect = 2e-12
Identities = 72/268 (26%), Positives = 123/268 (45%), Gaps = 50/268 (18%)
Query: 261 VRTLDGTEAPFSALGWRRL---VPAVPLSQLHPRGLRS-----CAVVMSAGAILNSSLGE 312
V+T E P+ G L V A+ S + P+ ++S C VV + + NSSLG+
Sbjct: 74 VKTPSAYELPYGTKGSEDLLLRVLAITSSSI-PKNIQSLRCRRCVVVGNGHRLRNSSLGD 132
Query: 313 EIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHF---IDSSLYKDVILVA 369
I+ +D V+R N+AP GYE DVG+KTT+R+ + S HF ++++ ++LVA
Sbjct: 133 AINKYDVVIRLNNAPVAGYEGDVGSKTTMRLFYPE-----SAHFDPKVENNPDTLLVLVA 187
Query: 370 WDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNP----NQP--FYILHPKFIWQLWDIIQE 423
+K D++ + ++R QP + ++PK I L E
Sbjct: 188 -------------FKAMDFHWIETILSDKKRVRKGFWKQPPLIWDVNPKQIRILNPFFME 234
Query: 424 NTKEKIQPNP----------PSSGFIGILIMMSMCREVHV--YEYIPSVRQTELCHYHEL 471
+K+ P P++G + I + + +C VH+ + Y + + + HY+E
Sbjct: 235 IAADKLLSLPMQQPRKIKQKPTTGLLAITLALHLCDLVHIAGFGYPDAYNKKQTIHYYE- 293
Query: 472 YYDAACTLGAYHPLLYEKLLVQR-LNMG 498
G+ H + E L ++R L MG
Sbjct: 294 QITLKSMAGSGHNVSQEALAIKRMLEMG 321
>gi|229892273 sialyltransferase 7C isoform 1 [Homo sapiens]
Length = 305
Score = 70.9 bits (172), Expect = 3e-12
Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 15/168 (8%)
Query: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTN 351
CA+V ++G ++ +G EID + R N+APT+GYE+DVG T IR+++ +L N
Sbjct: 80 CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
Query: 352 PSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHP 411
P + F +++ I V W P N+ YN+ + PN Y+
Sbjct: 140 PDYFFKEAN---TTIYVIWGP---FRNMRKDGNGIVYNMLKKTV---GIYPNAQIYVTTE 190
Query: 412 KFIWQLWDIIQENT-KEKIQPNP-PSSGFIGILIMMSMCREVHVYEYI 457
K + + ++ T K+++Q S+G+ L+ M C +HVY I
Sbjct: 191 KRMSYCDGVFKKETGKDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMI 238
>gi|28373086 sialyltransferase 6 isoform i [Homo sapiens]
Length = 413
Score = 69.3 bits (168), Expect = 8e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 185 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 239
Query: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 240 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 296
Query: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 297 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 356
Query: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
V + Y S L HY+E AA H + EK +++L
Sbjct: 357 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 400
>gi|28373082 sialyltransferase 6 isoform g [Homo sapiens]
Length = 359
Score = 69.3 bits (168), Expect = 8e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 131 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 185
Query: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 186 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 242
Query: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 243 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 302
Query: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
V + Y S L HY+E AA H + EK +++L
Sbjct: 303 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 346
>gi|28373078 sialyltransferase 6 isoform f [Homo sapiens]
Length = 429
Score = 69.3 bits (168), Expect = 8e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 201 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 255
Query: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 256 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 312
Query: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 313 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 372
Query: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
V + Y S L HY+E AA H + EK +++L
Sbjct: 373 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 416
>gi|28373070 sialyltransferase 6 isoform b [Homo sapiens]
Length = 390
Score = 69.3 bits (168), Expect = 8e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 162 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 216
Query: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 217 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 273
Query: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 274 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 333
Query: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
V + Y S L HY+E AA H + EK +++L
Sbjct: 334 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 377
>gi|28373068 sialyltransferase 6 isoform a [Homo sapiens]
Length = 444
Score = 69.3 bits (168), Expect = 8e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 216 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 270
Query: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 271 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 327
Query: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 328 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 387
Query: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
V + Y S L HY+E AA H + EK +++L
Sbjct: 388 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 431
>gi|5454060 sialyltransferase 6 isoform j [Homo sapiens]
Length = 375
Score = 69.3 bits (168), Expect = 8e-12
Identities = 66/225 (29%), Positives = 100/225 (44%), Gaps = 16/225 (7%)
Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 147 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 201
Query: 338 KTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQH 397
KTT+RI + + SL+ +L + + + YK+ +
Sbjct: 202 KTTLRITYPEGAMQRPEQYERDSLF---VLAGFKWQDFKWLKYIVYKERVSASDGFWKSV 258
Query: 398 RQRNPNQP--FYILHPKFIWQLWDI---IQENTKEKIQPNPPSSGFIGILIMMSMCREVH 452
R P +P IL+P FI + + N + N P+ G + + + + C EV
Sbjct: 259 ATRVPKEPPEIRILNPYFIQEAAFTLIGLPFNNGLMGRGNIPTLGSVAVTMALHGCDEVA 318
Query: 453 V--YEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRL 495
V + Y S L HY+E AA H + EK +++L
Sbjct: 319 VAGFGYDMSTPNAPL-HYYETVRMAAIKESWTHNIQREKEFLRKL 362
>gi|109633046 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 2 [Homo sapiens]
Length = 395
Score = 66.6 bits (161), Expect = 5e-11
Identities = 65/236 (27%), Positives = 101/236 (42%), Gaps = 32/236 (13%)
Query: 288 LHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ 347
L + R C V+ S G + LG ++ D V+R NSAP GY + VGNKTTIR+ +
Sbjct: 164 LKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPE 223
Query: 348 -----ILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYNLFTPYIQ 396
L S+ + L+K V +V + P+ L W Q
Sbjct: 224 GAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWK------------Q 271
Query: 397 HRQRNPNQP--FYILHPKFIWQ-LWDIIQENTKEK----IQPNPPSSGFIGILIMMSMCR 449
++ P QP F IL+P I + +DI+Q + + N P+ G I +++ +C
Sbjct: 272 VAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCD 331
Query: 450 EVHVYEYIPSVRQTEL-CHYHELYYDAACTLGAYHPLLYE-KLLVQRLNMGTQGDL 503
EV + + + Q HY + AA H + E K L++ + G DL
Sbjct: 332 EVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVKDL 387
>gi|109633044 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
isoform 1 [Homo sapiens]
Length = 418
Score = 66.6 bits (161), Expect = 5e-11
Identities = 65/236 (27%), Positives = 101/236 (42%), Gaps = 32/236 (13%)
Query: 288 LHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ 347
L + R C V+ S G + LG ++ D V+R NSAP GY + VGNKTTIR+ +
Sbjct: 187 LKAKTCRRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIRMTYPE 246
Query: 348 -----ILTNPSHHFIDSSLYKDV------ILVAWDPAPYSANLNLWYKKPDYNLFTPYIQ 396
L S+ + L+K V +V + P+ L W Q
Sbjct: 247 GAPLSDLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVRLFFWK------------Q 294
Query: 397 HRQRNPNQP--FYILHPKFIWQ-LWDIIQENTKEK----IQPNPPSSGFIGILIMMSMCR 449
++ P QP F IL+P I + +DI+Q + + N P+ G I +++ +C
Sbjct: 295 VAEKIPLQPKHFRILNPVIIKETAFDILQYSEPQSRFWGRDKNVPTIGVIAVVLATHLCD 354
Query: 450 EVHVYEYIPSVRQTEL-CHYHELYYDAACTLGAYHPLLYE-KLLVQRLNMGTQGDL 503
EV + + + Q HY + AA H + E K L++ + G DL
Sbjct: 355 EVSLAGFGYDLNQPRTPLHYFDSQCMAAMNFQTMHNVTTETKFLLKLVKEGVVKDL 410
>gi|28373074 sialyltransferase 6 isoform d [Homo sapiens]
Length = 277
Score = 65.1 bits (157), Expect = 2e-10
Identities = 33/66 (50%), Positives = 42/66 (63%), Gaps = 5/66 (7%)
Query: 278 RLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGN 337
RL PA L R C +V + G + N SLG ID +D V+R NSAP +G+EKDVG+
Sbjct: 147 RLTPA-----LDSLRCRRCIIVGNGGVLANKSLGSRIDDYDIVVRLNSAPVKGFEKDVGS 201
Query: 338 KTTIRI 343
KTT+RI
Sbjct: 202 KTTLRI 207
>gi|229892275 sialyltransferase 7C isoform 2 [Homo sapiens]
Length = 210
Score = 62.4 bits (150), Expect = 1e-09
Identities = 30/81 (37%), Positives = 48/81 (59%), Gaps = 7/81 (8%)
Query: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTN 351
CA+V ++G ++ +G EID + R N+APT+GYE+DVG T IR+++ +L N
Sbjct: 80 CAIVSNSGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKN 139
Query: 352 PSHHFIDSSLYKDVILVAWDP 372
P + F +++ I V W P
Sbjct: 140 PDYFFKEAN---TTIYVIWGP 157
>gi|110815855 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 3 [Homo sapiens]
Length = 380
Score = 62.4 bits (150), Expect = 1e-09
Identities = 57/211 (27%), Positives = 96/211 (45%), Gaps = 30/211 (14%)
Query: 276 WRRLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDV 335
+R L+P V S + + CAVV ++G + S G+EID D V R N APT +++DV
Sbjct: 144 FRSLLPDV--SPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDV 201
Query: 336 GNKTTIRIINSQILTNPSHHFID--------SSLYKDVILVAWDPAPY---SANLNLWYK 384
G KT + N IL ++ + SL K + W PA + SA +
Sbjct: 202 GRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVT---- 257
Query: 385 KPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIM 444
L +++HR + Q + P I Q + +N + + P S+G + +
Sbjct: 258 ---RTLVDFFVEHRGQLKVQ---LAWPGNIMQHVNRYWKN--KHLSPKRLSTGILMYTLA 309
Query: 445 MSMCREVHVY-----EYIPSVRQTELCHYHE 470
++C E+H+Y + P+ R+ HY++
Sbjct: 310 SAICEEIHLYGFWPFGFDPNTREDLPYHYYD 340
>gi|5174677 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 2 [Homo sapiens]
Length = 375
Score = 62.0 bits (149), Expect = 1e-09
Identities = 68/329 (20%), Positives = 133/329 (40%), Gaps = 59/329 (17%)
Query: 170 RRRVKKRHRRQRRSHVLEEGDDGDRLYSSMSRAFLYRL------WKGNVSSKMLNPRLQK 223
R V H + R+ V+ G + + + + + W+ N + L+ R++K
Sbjct: 42 RSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHN---QTLSLRIRK 98
Query: 224 AMKDYLTANKHGVRFRGKREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAV 283
+ +L A K +G + G ++ + R D T L + L
Sbjct: 99 QILKFLDAEKDISVLKGTLKPG----DIIHYIFDR------DSTMNVSQNL-YELLPRTS 147
Query: 284 PLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRI 343
PL H +CA+V ++G +LNS G+EID+H V+R N AP + Y +DVG KT +
Sbjct: 148 PLKNKH---FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVT 204
Query: 344 INSQILTNPSHHFIDSSLYKDVI--------LVAWDPAPYSAN-------LNLWYKKPDY 388
+N ++ ++++ + ++ + W PA + +N K
Sbjct: 205 MNPSVIQRAFEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKHHV 264
Query: 389 NLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMC 448
N+ T Y R + + +++ + K+ P++G + + C
Sbjct: 265 NVRTAYPSLRLLHAVRGYWLTN-----------------KVHIKRPTTGLLMYTLATRFC 307
Query: 449 REVHVYEY--IPSVRQTELCHYHELYYDA 475
+++++Y + P + YH YYD+
Sbjct: 308 KQIYLYGFWPFPLDQNQNPVKYH--YYDS 334
>gi|21264332 sialyltransferase 7A [Homo sapiens]
Length = 600
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/220 (27%), Positives = 100/220 (45%), Gaps = 37/220 (16%)
Query: 281 PAVPLSQLH----PRG-LR--SCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEK 333
P VP QL P G LR +CAVV + G + NS +G+EIDSHD V R + A +GYE+
Sbjct: 343 PPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHMGQEIDSHDYVFRLSGALIKGYEQ 402
Query: 334 DVGNKT-----TIRIINSQILTNPSHHFIDSSLYKDVILVAW---------------DPA 373
DVG +T T + +L + F + L KDV + + +
Sbjct: 403 DVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKDVRYLHFLEGTRDYEWLEALLMNQT 462
Query: 374 PYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWD-IIQENTKEKI--Q 430
S NL W++ F + H R + +LHP F+ + + ++ T + +
Sbjct: 463 VMSKNL-FWFRHRPQEAFREAL-HMDR-----YLLLHPDFLRYMKNRFLRSKTLDGAHWR 515
Query: 431 PNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHE 470
P++G + +L + +C +V Y +I + HY++
Sbjct: 516 IYRPTTGALLLLTALQLCDQVSAYGFITEGHERFSDHYYD 555
>gi|5902082 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Homo
sapiens]
Length = 350
Score = 61.6 bits (148), Expect = 2e-09
Identities = 51/221 (23%), Positives = 93/221 (42%), Gaps = 23/221 (10%)
Query: 290 PRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQIL 349
P R CAVV ++G + S G+++D H+ ++R N APT G+E+DVG++TT
Sbjct: 146 PHQCRRCAVVGNSGNLRGSGYGQDVDGHNFIMRMNQAPTVGFEQDVGSRTT--------- 196
Query: 350 TNPSHHFIDSSLYKDV-ILVAWDPAPYSANLNLWYKKP----DYNLFTPYIQHRQRNPNQ 404
HHF+ K++ V++ P+ LW ++ R +
Sbjct: 197 ----HHFMYPESAKNLPANVSFVLVPFKVLDLLWIASALSTGQIRFTYAPVKSFLRVDKE 252
Query: 405 PFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTE 464
I +P F + D E+ PS+G + + + +C EV+VY + R
Sbjct: 253 KVQIYNPAFFKYIHDRWTEH-----HGRYPSTGMLVLFFALHVCDEVNVYGFGADSRGNW 307
Query: 465 LCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGDLHR 505
++ Y H +E ++ L ++ +++R
Sbjct: 308 HHYWENNRYAGEFRKTGVHDADFEAHIIDMLAKASKIEVYR 348
>gi|28373094 sialyltransferase 7D isoform b [Homo sapiens]
Length = 218
Score = 60.1 bits (144), Expect = 5e-09
Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 305 ILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQ----ILTNPSHHFIDSS 360
+L S LG EIDS + V R N APT G+E DVG ++T+R+++ +L N SH+F +
Sbjct: 1 MLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLLLRNYSHYFQKA- 59
Query: 361 LYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDI 420
+D + + W + + + +Q + P Y + + I
Sbjct: 60 --RDTLYMVWGQGRHMDRV------LGGRTYRTLLQLTRMYPGLQVYTFTERMMAYCDQI 111
Query: 421 IQENTKEKIQPNPP--SSGFIGILIMMSMCREVHVYEYIPSVRQTELCH 467
Q+ T + + + S+G+ +++ + +C E+ VY + E H
Sbjct: 112 FQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSH 160
>gi|54234057 ST8 alpha-N-acetyl-neuraminide
alpha-2,8-sialyltransferase 6 [Homo sapiens]
Length = 398
Score = 58.5 bits (140), Expect = 1e-08
Identities = 55/210 (26%), Positives = 86/210 (40%), Gaps = 19/210 (9%)
Query: 296 CAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRG-YEKDVGNKTTIRIINSQILTNPSH 354
CAVV + G + S G EID D V R N PT G KDVG+KT + IN I+T
Sbjct: 186 CAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIIT---- 241
Query: 355 HFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNL-------FTPYIQHRQRNPNQPFY 407
+L + L D A Y + ++ P ++ F Y + Q
Sbjct: 242 -LKYGNLKEKKALFLEDIATYG---DAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVL 297
Query: 408 ILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCH 467
HPK+ L D+ + + S+G + + + +C+ V +Y + P + E
Sbjct: 298 FFHPKY---LKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIP 354
Query: 468 YHELYYDAACTLGAYHPLLYEKLLVQRLNM 497
YYD +H + E + +L+M
Sbjct: 355 VSHHYYDNKLPKHGFHQMPKEYSQILQLHM 384
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,431,528
Number of Sequences: 37866
Number of extensions: 1197764
Number of successful extensions: 3491
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3425
Number of HSP's gapped (non-prelim): 58
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.