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Search of human proteins with 21450796
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21450796 transmembrane protein 106A [Homo sapiens]
(262 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21450796 transmembrane protein 106A [Homo sapiens] 531 e-151
gi|197116389 transmembrane protein 106B [Homo sapiens] 196 2e-50
gi|40254893 transmembrane protein 106B [Homo sapiens] 196 2e-50
gi|219802834 transmembrane protein 106C isoform a [Homo sapiens] 138 6e-33
gi|13129026 transmembrane protein 106C isoform a [Homo sapiens] 138 6e-33
gi|219802857 transmembrane protein 106C isoform b [Homo sapiens] 132 3e-31
gi|219802797 transmembrane protein 106C isoform b [Homo sapiens] 132 3e-31
gi|134304835 killer cell immunoglobulin-like receptor, two domai... 30 1.6
gi|45505173 B cell RAG associated protein [Homo sapiens] 29 4.8
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] 29 4.8
gi|50539414 cellular modulator of immune recognition isoform 7 [... 28 6.2
gi|50539412 cellular modulator of immune recognition isoform 6 [... 28 6.2
gi|50539410 cellular modulator of immune recognition isoform 8 [... 28 6.2
gi|21687041 ribonuclease, RNase A family, 11 (non-active) [Homo ... 28 8.1
>gi|21450796 transmembrane protein 106A [Homo sapiens]
Length = 262
Score = 531 bits (1368), Expect = e-151
Identities = 262/262 (100%), Positives = 262/262 (100%)
Query: 1 MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCP 60
MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCP
Sbjct: 1 MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCP 60
Query: 61 TCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRSVI 120
TCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRSVI
Sbjct: 61 TCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRSVI 120
Query: 121 VQPAGLNSSTVAFDEADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLL 180
VQPAGLNSSTVAFDEADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLL
Sbjct: 121 VQPAGLNSSTVAFDEADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLL 180
Query: 181 LHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQ 240
LHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQ
Sbjct: 181 LHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQ 240
Query: 241 SYEYVDCRGNASVPHQLTPHPP 262
SYEYVDCRGNASVPHQLTPHPP
Sbjct: 241 SYEYVDCRGNASVPHQLTPHPP 262
>gi|197116389 transmembrane protein 106B [Homo sapiens]
Length = 274
Score = 196 bits (498), Expect = 2e-50
Identities = 110/258 (42%), Positives = 152/258 (58%), Gaps = 6/258 (2%)
Query: 1 MGKTFSQLG--SWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVT 58
MGK+ S L S +ED + S G + S P VT
Sbjct: 1 MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVT 60
Query: 59 CPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRS 118
CPTCQG+G+IP+ E QLVALIPY DQRL+P+ TKL+V +V +CL+ S VFFLFPRS
Sbjct: 61 CPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRS 120
Query: 119 VIVQPAGLNSSTVAFD--EADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVS 176
+ V+ G+ S+ V++D + IYLNITN LNI+N NYY + V +T +V V+G+
Sbjct: 121 IDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKAR 180
Query: 177 NNLLLHIGPLASEQMFYAVATKIRDENT--YKICTWLEIKVHHVLLHIQGTLTCSYLSHS 234
N + IGPL +Q+ Y V T I +E + Y CT + IKVH+++L +Q T+T +Y HS
Sbjct: 181 LNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHS 240
Query: 235 EQLVFQSYEYVDCRGNAS 252
EQ+ + Y+YVDC N +
Sbjct: 241 EQISQERYQYVDCGRNTT 258
>gi|40254893 transmembrane protein 106B [Homo sapiens]
Length = 274
Score = 196 bits (498), Expect = 2e-50
Identities = 110/258 (42%), Positives = 152/258 (58%), Gaps = 6/258 (2%)
Query: 1 MGKTFSQLG--SWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVT 58
MGK+ S L S +ED + S G + S P VT
Sbjct: 1 MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVSQFPYVEFTGRDSVT 60
Query: 59 CPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRS 118
CPTCQG+G+IP+ E QLVALIPY DQRL+P+ TKL+V +V +CL+ S VFFLFPRS
Sbjct: 61 CPTCQGTGRIPRGQENQLVALIPYSDQRLRPRRTKLYVMASVFVCLLLSGLAVFFLFPRS 120
Query: 119 VIVQPAGLNSSTVAFD--EADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVS 176
+ V+ G+ S+ V++D + IYLNITN LNI+N NYY + V +T +V V+G+
Sbjct: 121 IDVKYIGVKSAYVSYDVQKRTIYLNITNTLNITNNNYYSVEVENITAQVQFSKTVIGKAR 180
Query: 177 NNLLLHIGPLASEQMFYAVATKIRDENT--YKICTWLEIKVHHVLLHIQGTLTCSYLSHS 234
N + IGPL +Q+ Y V T I +E + Y CT + IKVH+++L +Q T+T +Y HS
Sbjct: 181 LNNITIIGPLDMKQIDYTVPTVIAEEMSYMYDFCTLISIKVHNIVLMMQVTVTTTYFGHS 240
Query: 235 EQLVFQSYEYVDCRGNAS 252
EQ+ + Y+YVDC N +
Sbjct: 241 EQISQERYQYVDCGRNTT 258
>gi|219802834 transmembrane protein 106C isoform a [Homo sapiens]
Length = 250
Score = 138 bits (347), Expect = 6e-33
Identities = 72/200 (36%), Positives = 118/200 (59%), Gaps = 4/200 (2%)
Query: 57 VTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFP 116
+TC TCQG+G IP E +LVALIP+ DQRL+P+ TK +V L++L+CL+ S +VFFLFP
Sbjct: 49 ITCLTCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFP 108
Query: 117 RSVIVQPAGLNSSTVAFDEAD--IYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQ 174
SV+V G+ V F++ D + L I L I N N+Y + VT L+ ++ +++ VV
Sbjct: 109 HSVLVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVST 168
Query: 175 VSNNLLLHIGPLASEQMFYAVATKIRD--ENTYKICTWLEIKVHHVLLHIQGTLTCSYLS 232
+ I P + + + + ++ Y CT EI VH++++ ++ ++ SY+
Sbjct: 169 YVTTNVSLIPPRSEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIG 228
Query: 233 HSEQLVFQSYEYVDCRGNAS 252
Q +++ YVDC GN++
Sbjct: 229 LMTQSSLETHHYVDCGGNST 248
>gi|13129026 transmembrane protein 106C isoform a [Homo sapiens]
Length = 250
Score = 138 bits (347), Expect = 6e-33
Identities = 72/200 (36%), Positives = 118/200 (59%), Gaps = 4/200 (2%)
Query: 57 VTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFP 116
+TC TCQG+G IP E +LVALIP+ DQRL+P+ TK +V L++L+CL+ S +VFFLFP
Sbjct: 49 ITCLTCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFP 108
Query: 117 RSVIVQPAGLNSSTVAFDEAD--IYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQ 174
SV+V G+ V F++ D + L I L I N N+Y + VT L+ ++ +++ VV
Sbjct: 109 HSVLVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVST 168
Query: 175 VSNNLLLHIGPLASEQMFYAVATKIRD--ENTYKICTWLEIKVHHVLLHIQGTLTCSYLS 232
+ I P + + + + ++ Y CT EI VH++++ ++ ++ SY+
Sbjct: 169 YVTTNVSLIPPRSEQLVNFTGKAEMGGPFSYVYFFCTVPEILVHNIVIFMRTSVKISYIG 228
Query: 233 HSEQLVFQSYEYVDCRGNAS 252
Q +++ YVDC GN++
Sbjct: 229 LMTQSSLETHHYVDCGGNST 248
>gi|219802857 transmembrane protein 106C isoform b [Homo sapiens]
Length = 231
Score = 132 bits (332), Expect = 3e-31
Identities = 72/198 (36%), Positives = 113/198 (57%), Gaps = 19/198 (9%)
Query: 57 VTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFP 116
+TC TCQG+G IP E +LVALIP+ DQRL+P+ TK +V L++L+CL+ S +VFFLFP
Sbjct: 49 ITCLTCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFP 108
Query: 117 RSVIVQPAGLNSSTVAFDEAD--IYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQ 174
SV+V G+ V F++ D + L I L I N N+Y + VT L+ ++ +++ VV
Sbjct: 109 HSVLVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNF 168
Query: 175 VSNNLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHS 234
+ GP + Y CT EI VH++++ ++ ++ SY+
Sbjct: 169 TGKAEM--GGPFS---------------YVYFFCTVPEILVHNIVIFMRTSVKISYIGLM 211
Query: 235 EQLVFQSYEYVDCRGNAS 252
Q +++ YVDC GN++
Sbjct: 212 TQSSLETHHYVDCGGNST 229
>gi|219802797 transmembrane protein 106C isoform b [Homo sapiens]
Length = 231
Score = 132 bits (332), Expect = 3e-31
Identities = 72/198 (36%), Positives = 113/198 (57%), Gaps = 19/198 (9%)
Query: 57 VTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFP 116
+TC TCQG+G IP E +LVALIP+ DQRL+P+ TK +V L++L+CL+ S +VFFLFP
Sbjct: 49 ITCLTCQGTGYIPTEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFP 108
Query: 117 RSVIVQPAGLNSSTVAFDEAD--IYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQ 174
SV+V G+ V F++ D + L I L I N N+Y + VT L+ ++ +++ VV
Sbjct: 109 HSVLVDDDGIKVVKVTFNKQDSLVILTIMATLKIRNSNFYTVAVTSLSSQIQYMNTVVNF 168
Query: 175 VSNNLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHS 234
+ GP + Y CT EI VH++++ ++ ++ SY+
Sbjct: 169 TGKAEM--GGPFS---------------YVYFFCTVPEILVHNIVIFMRTSVKISYIGLM 211
Query: 235 EQLVFQSYEYVDCRGNAS 252
Q +++ YVDC GN++
Sbjct: 212 TQSSLETHHYVDCGGNST 229
>gi|134304835 killer cell immunoglobulin-like receptor, two domains,
short cytoplasmic tail, 5 [Homo sapiens]
Length = 304
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 18/76 (23%)
Query: 178 NLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQL 237
+LL H GPL ++ E T + W ++ H LLH +GT +H+ +L
Sbjct: 30 SLLAHPGPL------------VKSEETVILQCWSDVMFEHFLLHREGT-----FNHTLRL 72
Query: 238 VFQSYEYVDCRGNASV 253
+ + + V +GN S+
Sbjct: 73 IGEHIDGVS-KGNFSI 87
>gi|45505173 B cell RAG associated protein [Homo sapiens]
Length = 561
Score = 28.9 bits (63), Expect = 4.8
Identities = 20/78 (25%), Positives = 33/78 (42%), Gaps = 12/78 (15%)
Query: 46 VPCEGTADASFVTCPTCQGSGKIPQELEKQLVALIPY------------GDQRLKPKHTK 93
V C+G CPTC+G KI ++ + + L+ G R K
Sbjct: 21 VNCQGGPHHGHQACPTCKGENKILFRVDSKQMNLLAVLEVRTEGNENWGGFLRFKKGKRC 80
Query: 94 LFVFLAVLICLVTSSFIV 111
VF +++ LV +S+I+
Sbjct: 81 SLVFGLIIMTLVMASYIL 98
>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
Length = 2093
Score = 28.9 bits (63), Expect = 4.8
Identities = 26/103 (25%), Positives = 39/103 (37%), Gaps = 14/103 (13%)
Query: 119 VIVQPAGLNSSTVAFDEADIYLNITNILNISNGNYYPIMVTQLTL-------EVLHLSLV 171
+I Q ST+ D+ +T I N Y + V L+ E++H +
Sbjct: 469 LITQIKSYQDSTIK----DLSHEVTRIEKHQNRQKYGLCVIFLSCTMMPNFKELIHFEVS 524
Query: 172 VGQVSNNLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIK 214
+G N + L+ PL S + V I D N Y W K
Sbjct: 525 IGHYGNKMDLNYKPLVSSTPYSPV---IYDGNIYHYVPWYNTK 564
>gi|50539414 cellular modulator of immune recognition isoform 7
[Homo sapiens]
Length = 291
Score = 28.5 bits (62), Expect = 6.2
Identities = 16/45 (35%), Positives = 21/45 (46%)
Query: 21 SSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGS 65
+S PA S S T SS+ C CEG ++ +T C GS
Sbjct: 58 ASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGS 102
>gi|50539412 cellular modulator of immune recognition isoform 6
[Homo sapiens]
Length = 291
Score = 28.5 bits (62), Expect = 6.2
Identities = 16/45 (35%), Positives = 21/45 (46%)
Query: 21 SSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGS 65
+S PA S S T SS+ C CEG ++ +T C GS
Sbjct: 58 ASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGS 102
>gi|50539410 cellular modulator of immune recognition isoform 8
[Homo sapiens]
Length = 291
Score = 28.5 bits (62), Expect = 6.2
Identities = 16/45 (35%), Positives = 21/45 (46%)
Query: 21 SSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGS 65
+S PA S S T SS+ C CEG ++ +T C GS
Sbjct: 58 ASAPAPVSSFSRTSITPSSQDICRICHCEGDDESPLITPCHCTGS 102
>gi|21687041 ribonuclease, RNase A family, 11 (non-active) [Homo
sapiens]
Length = 199
Score = 28.1 bits (61), Expect = 8.1
Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 163 LEVLHLSLVVGQVSNNLLLHIGP-LASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLH 221
L +L L LV+ + S + + I E+M Y +A +++ T +EI ++ +LL
Sbjct: 6 LLLLSLGLVLAEASESTMKIIKEEFTDEEMQYDMAKSGQEKQT------IEILMNPILLV 59
Query: 222 IQGTLTCSYLSHSEQLV-FQSYEYVDCRGNAS 252
+L+ S S L+ F+S Y D +GN+S
Sbjct: 60 KNTSLSMSKDDMSSTLLTFRSLHYNDPKGNSS 91
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,806,990
Number of Sequences: 37866
Number of extensions: 398841
Number of successful extensions: 1015
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 997
Number of HSP's gapped (non-prelim): 14
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.