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Search of human proteins with 114155133
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo
sapiens]
(4486 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 8989 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 5761 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 5712 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 5709 0.0
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 5373 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2314 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2205 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 2048 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 2020 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 1941 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1930 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1923 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1920 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 1624 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1408 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1251 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 969 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 754 0.0
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 184 2e-45
gi|4502395 beclin 1 [Homo sapiens] 47 4e-04
gi|34577114 cytomatrix protein p110 [Homo sapiens] 46 7e-04
gi|62243374 MAD1-like 1 protein [Homo sapiens] 44 0.004
gi|62243369 MAD1-like 1 protein [Homo sapiens] 44 0.004
gi|62243332 MAD1-like 1 protein [Homo sapiens] 44 0.004
gi|118498356 kinectin 1 isoform a [Homo sapiens] 44 0.005
gi|33620775 kinectin 1 isoform a [Homo sapiens] 44 0.005
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 44 0.005
gi|118498362 kinectin 1 isoform b [Homo sapiens] 43 0.008
gi|42794779 myosin 18A isoform b [Homo sapiens] 42 0.011
gi|28416946 myosin 18A isoform a [Homo sapiens] 42 0.011
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 8989 bits (23325), Expect = 0.0
Identities = 4486/4486 (100%), Positives = 4486/4486 (100%)
Query: 1 MRLAEERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFL 60
MRLAEERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFL
Sbjct: 1 MRLAEERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFL 60
Query: 61 GRDAAEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAV 120
GRDAAEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAV
Sbjct: 61 GRDAAEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAV 120
Query: 121 VCGDLPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQV 180
VCGDLPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQV
Sbjct: 121 VCGDLPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQV 180
Query: 181 KGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPL 240
KGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPL
Sbjct: 181 KGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPL 240
Query: 241 LQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVV 300
LQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVV
Sbjct: 241 LQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVV 300
Query: 301 AALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTV 360
AALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTV
Sbjct: 301 AALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTV 360
Query: 361 LLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFK 420
LLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFK
Sbjct: 361 LLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFK 420
Query: 421 ENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQ 480
ENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQ
Sbjct: 421 ENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQ 480
Query: 481 QMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGL 540
QMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGL
Sbjct: 481 QMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGL 540
Query: 541 EHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPV 600
EHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPV
Sbjct: 541 EHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPV 600
Query: 601 HKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYET 660
HKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYET
Sbjct: 601 HKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYET 660
Query: 661 RLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPE 720
RLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPE
Sbjct: 661 RLYEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPE 720
Query: 721 TAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLN 780
TAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLN
Sbjct: 721 TAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLN 780
Query: 781 WKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTKDGKRESLLSLD 840
WKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTKDGKRESLLSLD
Sbjct: 781 WKTEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTKDGKRESLLSLD 840
Query: 841 DRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIE 900
DRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIE
Sbjct: 841 DRHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIE 900
Query: 901 CSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIP 960
CSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIP
Sbjct: 901 CSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIP 960
Query: 961 SLVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVED 1020
SLVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVED
Sbjct: 961 SLVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVED 1020
Query: 1021 RKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKV 1080
RKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKV
Sbjct: 1021 RKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKV 1080
Query: 1081 FDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKG 1140
FDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKG
Sbjct: 1081 FDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKG 1140
Query: 1141 DFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNN 1200
DFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNN
Sbjct: 1141 DFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNN 1200
Query: 1201 IKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDA 1260
IKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDA
Sbjct: 1201 IKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDA 1260
Query: 1261 RHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWE 1320
RHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWE
Sbjct: 1261 RHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWE 1320
Query: 1321 TTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPA 1380
TTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPA
Sbjct: 1321 TTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPA 1380
Query: 1381 IRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKEL 1440
IRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKEL
Sbjct: 1381 IRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKEL 1440
Query: 1441 QTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQK 1500
QTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQK
Sbjct: 1441 QTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQK 1500
Query: 1501 KLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKI 1560
KLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKI
Sbjct: 1501 KLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKI 1560
Query: 1561 PNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGT 1620
PNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGT
Sbjct: 1561 PNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGT 1620
Query: 1621 APQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWL 1680
APQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWL
Sbjct: 1621 APQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWL 1680
Query: 1681 NHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEE 1740
NHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEE
Sbjct: 1681 NHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEE 1740
Query: 1741 GYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDN 1800
GYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDN
Sbjct: 1741 GYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDN 1800
Query: 1801 AQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSL 1860
AQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSL
Sbjct: 1801 AQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSL 1860
Query: 1861 HLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1920
HLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC
Sbjct: 1861 HLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGC 1920
Query: 1921 FDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRT 1980
FDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRT
Sbjct: 1921 FDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRT 1980
Query: 1981 ELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHY 2040
ELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHY
Sbjct: 1981 ELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHY 2040
Query: 2041 DWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPA 2100
DWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPA
Sbjct: 2041 DWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPA 2100
Query: 2101 LDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQV 2160
LDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQV
Sbjct: 2101 LDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQV 2160
Query: 2161 LRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDG 2220
LRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDG
Sbjct: 2161 LRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDG 2220
Query: 2221 PKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVS 2280
PKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVS
Sbjct: 2221 PKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVS 2280
Query: 2281 RAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIP 2340
RAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIP
Sbjct: 2281 RAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIP 2340
Query: 2341 EQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSK 2400
EQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSK
Sbjct: 2341 EQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSK 2400
Query: 2401 WWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRV 2460
WWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRV
Sbjct: 2401 WWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRV 2460
Query: 2461 CYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVL 2520
CYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVL
Sbjct: 2461 CYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVL 2520
Query: 2521 EKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLS 2580
EKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLS
Sbjct: 2521 EKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLS 2580
Query: 2581 LKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF 2640
LKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF
Sbjct: 2581 LKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF 2640
Query: 2641 PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST 2700
PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST
Sbjct: 2641 PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST 2700
Query: 2701 WDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFA 2760
WDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFA
Sbjct: 2701 WDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFA 2760
Query: 2761 NGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGN 2820
NGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGN
Sbjct: 2761 NGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGN 2820
Query: 2821 ALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVF 2880
ALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVF
Sbjct: 2821 ALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVF 2880
Query: 2881 LMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKF 2940
LMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKF
Sbjct: 2881 LMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKF 2940
Query: 2941 FIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNT 3000
FIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNT
Sbjct: 2941 FIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNT 3000
Query: 3001 EGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRK 3060
EGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRK
Sbjct: 3001 EGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRK 3060
Query: 3061 ELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSR 3120
ELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSR
Sbjct: 3061 ELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSR 3120
Query: 3121 EKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGS 3180
EKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGS
Sbjct: 3121 EKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGS 3180
Query: 3181 PPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKA 3240
PPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKA
Sbjct: 3181 PPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKA 3240
Query: 3241 IRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQ 3300
IRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQ
Sbjct: 3241 IRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQ 3300
Query: 3301 EKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENV 3360
EKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENV
Sbjct: 3301 EKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENV 3360
Query: 3361 RWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVT 3420
RWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVT
Sbjct: 3361 RWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVT 3420
Query: 3421 PALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKY 3480
PALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKY
Sbjct: 3421 PALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKY 3480
Query: 3481 GEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGD 3540
GEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGD
Sbjct: 3481 GEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGD 3540
Query: 3541 KECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQ 3600
KECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQ
Sbjct: 3541 KECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQ 3600
Query: 3601 LKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQE 3660
LKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQE
Sbjct: 3601 LKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQE 3660
Query: 3661 AKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPD 3720
AKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPD
Sbjct: 3661 AKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPD 3720
Query: 3721 ESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRS 3780
ESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRS
Sbjct: 3721 ESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRS 3780
Query: 3781 PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQ 3840
PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQ
Sbjct: 3781 PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQ 3840
Query: 3841 EWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMF 3900
EWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMF
Sbjct: 3841 EWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMF 3900
Query: 3901 FILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQN 3960
FILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQN
Sbjct: 3901 FILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQN 3960
Query: 3961 IHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPT 4020
IHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPT
Sbjct: 3961 IHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPT 4020
Query: 4021 GMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNT 4080
GMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNT
Sbjct: 4021 GMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNT 4080
Query: 4081 GDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEML 4140
GDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEML
Sbjct: 4081 GDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEML 4140
Query: 4141 EGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVL 4200
EGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVL
Sbjct: 4141 EGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVL 4200
Query: 4201 ELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECG 4260
ELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECG
Sbjct: 4201 ELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECG 4260
Query: 4261 RMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAW 4320
RMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAW
Sbjct: 4261 RMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAW 4320
Query: 4321 FPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDM 4380
FPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDM
Sbjct: 4321 FPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDM 4380
Query: 4381 TKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQ 4440
TKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQ
Sbjct: 4381 TKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQ 4440
Query: 4441 DCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI 4486
DCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI
Sbjct: 4441 DCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI 4486
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 5761 bits (14946), Expect = 0.0
Identities = 2821/4485 (62%), Positives = 3523/4485 (78%), Gaps = 40/4485 (0%)
Query: 22 DRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGPRPLLVVRPGPRGL 81
D RL L ++ L+ W + G+ E L F + + +LV+ G+
Sbjct: 6 DVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQ----VLVLTLNAAGM 61
Query: 82 AIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSEVV 141
I P L P+S +K ++F++T E D++R ++ GD+ P++ L A+ EV+
Sbjct: 62 II-PCLGF-PQS--LKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVL 117
Query: 142 LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201
+L +N WP ++ ED+ + H L+ ++ V+ ++KGKTLLP+P ++
Sbjct: 118 SSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLES 177
Query: 202 SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261
E + S+D +++AIE+ +I WS+Q++ VL ++S+Q LL G +P P+VE EFW +R +
Sbjct: 178 MERIPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLN 237
Query: 262 LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321
LK I+ QL V + ++L+K +S Y+PA + +Y +V L EA DI ++L PL+ LE
Sbjct: 238 LKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLE 297
Query: 322 ALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPED 381
+E A+F + + +L +C IWAT + Y +P R+ V+LQE CN +I+ +LSPE+
Sbjct: 298 EMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEE 357
Query: 382 LLRS---EVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVR 438
+L+ E+EE + + + L Q + N+ +FK+ + V W+F SSL F R
Sbjct: 358 VLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVP-WEFPSSLAFSR 416
Query: 439 LDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSS 498
++ F ++ +E L KTA++F KL K+E GVRGN L V ++++E E+ ++ +
Sbjct: 417 INSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFA---- 472
Query: 499 DCLY--------------LQSTD--FENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEH 542
DC Y L D F+ D ++F K++DLDRRL TIF Q FDD ++
Sbjct: 473 DCKYDPLDPGDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKS 532
Query: 543 AFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHK 602
+ KLL + G L+ERPL+ + + +Y V++++F+ +LD +++Y + E +HK
Sbjct: 533 SAKLLYMCGGLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHK 592
Query: 603 NMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRL 662
NMP VAG L+W+ EL++R++ + + HP M AE K QKY++M+ LL + ++
Sbjct: 593 NMPPVAGQLKWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKI 652
Query: 663 YEDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETA 722
Y+ W V + +NL QPL+ RD + I +NF+ L++VL+E+ YL ++ K +P++A
Sbjct: 653 YQQWVAGVDQDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSA 712
Query: 723 AAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWK 782
++FS + +R+ V NLEL+ WYN+VMK VEF L++ EL+ ID++L +AE TL W
Sbjct: 713 ESLFSENETFRKFVGNLELIVGWYNEVMKA---VEFLLIKSELEAIDVKLLSAETTLFWN 769
Query: 783 TEGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTW-VTPIFKTKDGKRESLLSLDD 841
EG+ Y+ E+ +H+L+ R+QK K N+E I MK W P+F+ KD K+E+LL LD
Sbjct: 770 GEGVFQYIQEVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDG 829
Query: 842 RHDRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIEC 901
R + K Y ++++G+KI A+V EN LF AD S WK YV ID+++L+ F I
Sbjct: 830 RIANLNKRYAAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRK 889
Query: 902 SLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPS 961
SL +L++N + P+FE ++ L L F P+LE G GF ++EGL+ I+ +
Sbjct: 890 SLSFLMDNMVIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVAR 949
Query: 962 LVPRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDR 1021
L+PRL+ +Y++DL+ DL MR + V M YQ +F +YSYL+ ++
Sbjct: 950 LIPRLAKDR--MNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNL 1007
Query: 1022 KEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVF 1081
+E + FL+YG +T E+++ +D IP+ PP L+QF+ QIDSYE LYEEV + E KVF
Sbjct: 1008 QEFMKNFLIYGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVF 1067
Query: 1082 DGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGD 1141
GW++ D RPFK +LL+ I+RW +FK+HL +HVT+SLA+L+AF+K + GL K +++GD
Sbjct: 1068 HGWLQCDCRPFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGD 1127
Query: 1142 FQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNI 1201
+ GLVE+MGHLM VKERQ+ TD MFEPLKQTIELLKTY +E+PE + +L+ELPE W N
Sbjct: 1128 YDGLVEVMGHLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANT 1187
Query: 1202 KKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDAR 1261
KK+AI VK VAPLQANEV++LR++C F+ +Q +F E+F +EAPF F +P++ L+ +
Sbjct: 1188 KKLAIQVKLTVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQ 1247
Query: 1262 HIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWET 1321
I ME M ++S+S LFEV VPDYKQL+ C +EV LKELWD + +V +SI W+T
Sbjct: 1248 QKSISAMEGIMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKT 1307
Query: 1322 TPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAI 1381
T W++INVE M+++CK+FA+ +R+LDKE++ WDAF GL++TV N ++SLRAV+ELQNPAI
Sbjct: 1308 TKWKDINVEQMDIDCKKFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAI 1367
Query: 1382 RERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQ 1441
RERHW+QLMQAT V F M ++TTLA LLQL LH YEDEVR IVDKA KE GMEK LK L
Sbjct: 1368 RERHWQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALD 1427
Query: 1442 TTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKK 1501
+TW+ MEFQ+EPHPRT +L S E L+E LEDNQVQLQNL+MSKY+A FL+EV+ WQ+K
Sbjct: 1428 STWSMMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQK 1487
Query: 1502 LSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIP 1561
LST D+VISIWFEVQRTW+HLESIF GSEDIR QLP DS+RF+ I+ +FK L DA K P
Sbjct: 1488 LSTADSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTP 1547
Query: 1562 NVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTA 1621
NVV+ T+KPGLY KLE ++ L +CEKALAEYL+TKRLAFPRFYF+SS+DLLDILSNG
Sbjct: 1548 NVVEATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGND 1607
Query: 1622 PQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLN 1681
P +V RHLSKLFD++ K++F+LDAS +P K LGMYSKE+EY+ F + CD SGQVE+WLN
Sbjct: 1608 PVEVSRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLN 1667
Query: 1682 HVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEG 1741
VL M +T+RHE+ E V YEEKPREQW+ D+PAQVALTCTQIWWTTEVG+AFARLEEG
Sbjct: 1668 RVLDRMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEG 1727
Query: 1742 YESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNA 1801
YE+A++DY KKQ++QL LIT+L+G L+ GDR KIMTICTIDVHARDVVAKMI KV+++
Sbjct: 1728 YENAIRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAKVESS 1787
Query: 1802 QAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLH 1861
QAF W +QLRHRWD+E +HCFANICDAQ YSYEYLGNTPRLVITPLTDRCYITLTQSLH
Sbjct: 1788 QAFTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLH 1847
Query: 1862 LTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCF 1921
L M GAPAGPAGTGKTETTKDLGRALG +VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCF
Sbjct: 1848 LIMGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCF 1907
Query: 1922 DEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTE 1981
DEFNRISVEVLSV+AVQVK +QDAIR KK+ F+FLGE I L P+VGIFITMNPGYAGR E
Sbjct: 1908 DEFNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAE 1967
Query: 1982 LPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYD 2041
LPENLK+LFRPCAMVVPDFELICEIML+AEGF+EA+ LARKFITLY LCKELLSKQDHYD
Sbjct: 1968 LPENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYD 2027
Query: 2042 WGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPAL 2101
WGLRAIKSVLVVAGSLKRGDP R EDQVLMR+LRDFNIPKIVTDD+P+FMGLIGDLFPAL
Sbjct: 2028 WGLRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPAL 2087
Query: 2102 DVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVL 2161
DVPR+RD NFE +++++IV+LKLQAED+FVLKVVQLEELL VRHSVF+VG AG+GKSQVL
Sbjct: 2088 DVPRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVL 2147
Query: 2162 RSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGP 2221
+SL+KTYQ +KR+PV DL+PKAVT DELFGIINP T EWKDGLFS+IMR+LANITHDGP
Sbjct: 2148 KSLNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGP 2207
Query: 2222 KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSR 2281
KWI+LDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN TM+L+FEISHLRTATPATVSR
Sbjct: 2208 KWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSR 2267
Query: 2282 AGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPE 2341
AGILYINPADLGWNP VSSWIE+R++Q+E+ANL ILFDKYLPTCLD LR FKKI P+PE
Sbjct: 2268 AGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPE 2327
Query: 2342 QSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKW 2401
+++Q + +LLECLLT + +P D P+E+YE YFVF WAFGGAM QDQLVDYR EFSKW
Sbjct: 2328 ITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKW 2387
Query: 2402 WLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVC 2461
W+ EFKT+KFPSQGTIFDYYIDP+TKKF PW+ VP FE DP++PLQA LVHT+ETIR+
Sbjct: 2388 WINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIR 2447
Query: 2462 YFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLE 2521
YFM+ LM + PVMLVG AGTGKSVL+G KL SL+ + YLV+ VPFN+YTTSAMLQ VLE
Sbjct: 2448 YFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLE 2507
Query: 2522 KPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSL 2581
KPLEKK+GRNYGPPG KKL+YFIDDMNMPEVD YGTV PHT+IRQH+D+ HWYDR KL+L
Sbjct: 2508 KPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTL 2567
Query: 2582 KEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFP 2641
K+I N QYV+CMNPT+GSFTI+ RLQRHF VF +SFPG +AL++IY+ ILTQHL +
Sbjct: 2568 KDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVS 2627
Query: 2642 ASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTW 2701
++Q+ L+ ALA HQKI TFLPT IKFHY+FNLRD +NIFQG+LFS+ E +K+
Sbjct: 2628 MAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPL 2687
Query: 2702 DLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFAN 2761
DL+RL+LHE+ RVY DKMV+EKD + ++ KK FDD+ D + PN++CHFA
Sbjct: 2688 DLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDEL-LFAKPNIFCHFAQ 2746
Query: 2762 GIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNA 2821
GIG+PKY+PV L + LV+ L+++NEVN VM+LVLFEDA+ H+C INRILESPRGNA
Sbjct: 2747 GIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNA 2806
Query: 2822 LLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFL 2881
LLVGVGGSGKQSL+RLAA+IS +DVFQITL+KGY I D K+DLA+ +KA VKN+ +VFL
Sbjct: 2807 LLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFL 2866
Query: 2882 MTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFF 2941
MTD+QVA+E+FLVLINDLLASGEIP L+ +DEVENIIS++R +VKS G+ D RE CWKFF
Sbjct: 2867 MTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFF 2926
Query: 2942 IDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTE 3001
I+++RRQLKV LCFSPVG+ LRVR+RKFPA+VNCTAI WFHEWP+ AL SVS RFL+ TE
Sbjct: 2927 IEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETE 2986
Query: 3002 GIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKE 3061
GI P +K SIS FM++VHT+VN+ S+ YL+ E+RYNYTTPK+FLE I+LYQ+LL + R E
Sbjct: 2987 GI-PVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTE 3045
Query: 3062 LKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSRE 3121
L K ERLENGL+KL ST++QVDDLKAKLA QE ELKQKNE AD+LIQVVG+E +KVS+E
Sbjct: 3046 LVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKE 3105
Query: 3122 KAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSP 3181
KA+AD+EE KV VI V +KQK CE DLAKAEPAL AAQ AL+TLNK NLTELKSFGSP
Sbjct: 3106 KAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSP 3165
Query: 3182 PLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAI 3241
P AV NV+AAVM+L AP G++PKD+SWKAAK+ M KVD FLDSL F+KE+I E CLKA
Sbjct: 3166 PDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAF 3225
Query: 3242 RPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQE 3301
+PY +P F+PEF+ +KS AAAGLCSW INIVRFYEV+CDV PKRQAL +A A+L AQE
Sbjct: 3226 KPYQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQE 3285
Query: 3302 KLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVR 3361
KL+ IK KIA LN NL+ LT+ FEKATA+K+KCQQEA+ T I LANRLVGGLASEN+R
Sbjct: 3286 KLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIR 3345
Query: 3362 WADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTP 3421
WA++V+NF+ Q TLCGD+LLI+AF+SY+G+FTKKYR L+++ W PY+ LK PIP+T
Sbjct: 3346 WAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITN 3405
Query: 3422 ALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYG 3481
LDPL +L DDADVA W N+GLP+DRMS ENATIL N ERWPL+VD QLQGIKWIKNKY
Sbjct: 3406 GLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYR 3465
Query: 3482 EDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDK 3541
+L+ ++GQK YL +IEQA+ G +LIEN+ E++DPVL PLLGR IKKG++IKIGDK
Sbjct: 3466 SELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDK 3525
Query: 3542 ECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQL 3601
E EY+PKFRLILHTK NPHY+PE+QAQ TLINF VTRDGLEDQLLAAVV+ ERPDLEQL
Sbjct: 3526 EVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQL 3585
Query: 3602 KSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEA 3661
K++LTK QN FKI LK LEDSLL+RLS+ASGNFLG+T LVENLE TK TA+E+E+KV EA
Sbjct: 3586 KANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEA 3645
Query: 3662 KVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDE 3721
K+TEVKINEARE+YRPAA RASLLYFI+NDL+KI+P+YQFSLKAF++VF+KA++R P
Sbjct: 3646 KITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPAN 3705
Query: 3722 SLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSP 3781
+++RV NL D IT+SVY YT RGLFE DKL +LAQ+TFQ+L M +E+N VELDFLLR P
Sbjct: 3706 EVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFP 3765
Query: 3782 VQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQE 3841
+ G SPV+FL HQ WG +K LS M+EF NLD DIEGSAK WKK VESE PEKE P+E
Sbjct: 3766 FKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKE 3825
Query: 3842 WKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFF 3901
WKNKTALQ+LCM+R +RPDRMTYA+++FVEEK+GSK+V GR+++F+ S+EES P+T +FF
Sbjct: 3826 WKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFF 3885
Query: 3902 ILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNI 3961
ILSPGVDPLKDVE+ G+KLG+T +N HNVSLGQGQEVVAE ALD+AA+KGHWVILQNI
Sbjct: 3886 ILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQNI 3945
Query: 3962 HLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTG 4021
HLVA+WL TL+KKLE +S SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTG
Sbjct: 3946 HLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTG 4005
Query: 4022 MHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTG 4081
MHANLHKALD FTQDTLEMC++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN G
Sbjct: 4006 MHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNG 4065
Query: 4082 DLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLE 4141
DLTIS+NVLYN+LEAN KVP+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLE
Sbjct: 4066 DLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLE 4125
Query: 4142 GELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLE 4201
G++ LAPGF +P N+DY GYH+YID LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE
Sbjct: 4126 GDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLE 4185
Query: 4202 LQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVEERTPYIVVAFQECGR 4261
+QP+++ + G G +REEKVKA+L++ILE++ + FN+ E+MAK E+TPY+VVAFQEC R
Sbjct: 4186 MQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVVAFQECER 4245
Query: 4262 MNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWF 4321
MNILT E++RSL+EL LGLKGELT+T+ +E+L AL++D VP++W RAYPS GLAAW+
Sbjct: 4246 MNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSMMGLAAWY 4305
Query: 4322 PDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMT 4381
DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIMQS ARKNEWPLD+M L ++T
Sbjct: 4306 ADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKMCLSVEVT 4365
Query: 4382 KKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQD 4441
KKNRE+ +PPREG+Y++GLFMEGA WDTQ G+I EA+LK+LTP MPV+FIKAIP D+ +
Sbjct: 4366 KKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKAIPVDRME 4425
Query: 4442 CRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQI 4486
+++Y CPVYKT RGPTYVWTFNLKTKE +KW+LA VALLLQ+
Sbjct: 4426 TKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQV 4470
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 5712 bits (14817), Expect = 0.0
Identities = 2806/4506 (62%), Positives = 3513/4506 (77%), Gaps = 67/4506 (1%)
Query: 22 DRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGPRPLLVVRPGPRGL 81
D RL L ++ L+ W + G+ E L F + + +LV+ G+
Sbjct: 6 DVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQ----VLVLTLNAAGM 61
Query: 82 AIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSEVV 141
I P L P+S +K ++F++T E D++R ++ GD+ P++ L A+ EV+
Sbjct: 62 II-PCLGF-PQS--LKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVL 117
Query: 142 LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201
+L +N WP ++ ED+ + H L+ ++ V+ ++KGKTLLP+P ++
Sbjct: 118 SSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLES 177
Query: 202 SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261
E + S+D +++AIE+ +I WS+Q++ VL ++S+Q LL G +P P+VE EFW +R +
Sbjct: 178 MERIPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLN 237
Query: 262 LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321
LK I+ QL V + ++L+K +S Y+PA + +Y +V L EA DI ++L PL+ LE
Sbjct: 238 LKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLE 297
Query: 322 ALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPED 381
+E A+F + + +L +C IWAT + Y +P R+ V+LQE CN +I+ +LSPE+
Sbjct: 298 EMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEE 357
Query: 382 LLRS---EVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVR 438
+L+ E+EE + + + L Q + N+ +FK+ + V W+F SSL F R
Sbjct: 358 VLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVP-WEFPSSLAFSR 416
Query: 439 LDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSS 498
++ F ++ +E L KTA++F KL K+E GVRGN L V ++++E E+ ++ +
Sbjct: 417 INSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKY 476
Query: 499 DCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLERPL 558
D L ++F+ D ++F K++DLDRRL TIF Q FDD ++ + KLL + G L+ERPL
Sbjct: 477 DPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPL 536
Query: 559 VARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELR 618
+ + + +Y V++++F+ +LD +++Y + E +HKNMP VAG L+W+ EL+
Sbjct: 537 ILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQ 596
Query: 619 QRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNL 678
+R++ + + HP M AE K QKY++M+ LL + ++Y+ W V + +NL
Sbjct: 597 ERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNL 656
Query: 679 SQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVAN 738
QPL+ RD + I +NF+ L++VL+E+ YL ++ K +P++A ++FS + +R+ V N
Sbjct: 657 GQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGN 716
Query: 739 LELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIH 798
LEL+ WYN++ + VEF L++ EL+ ID++L +AE TL W EG+ Y+ E+ +H
Sbjct: 717 LELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILH 776
Query: 799 DLEQRIQKTKDNVEEIQNIMKTW-VTPIFKTKDGKRESLLSLDDRHDRMEKYYNLIKESG 857
+L+ R+QK K N+E I MK W P+F+ KD K+E+LL LD R + K Y ++++G
Sbjct: 777 NLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAG 836
Query: 858 LKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSLKYLLENTECKAGLT 917
+KI A+V EN LF AD S WK YV ID+++L+ F I SL +L++N +
Sbjct: 837 VKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIA 896
Query: 918 PIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQV 977
P+FE ++ L L F P+LE G GF ++EGL+ I+ + L+PRL+ +Y++
Sbjct: 897 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDR--MNYKM 954
Query: 978 DLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHILTP 1037
DL+ DL MR + V M YQ +F +YSYL+ ++ +E + FL+YG +T
Sbjct: 955 DLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTA 1014
Query: 1038 EEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLL 1097
E+++ +D IP+ PP L+QF+ QIDSYE LYEEV + E KVF GW++ D RPFK +LL
Sbjct: 1015 EDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALL 1074
Query: 1098 NIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKE 1157
+ I+RW +FK+HL +HVT+SLA+L+AF+K + GL K +++GD+ GLVE+MGHLM VKE
Sbjct: 1075 STIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKE 1134
Query: 1158 RQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQA 1217
RQ+ TD MFEPLKQTIELLKTY +E+PE + +L+ELPE W N KK+AI VK VAPLQA
Sbjct: 1135 RQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQA 1194
Query: 1218 NEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISE 1277
NEV++LR++C F+ +Q +F E+F +EAPF F +P++ L+ ++ ++ M ++S+
Sbjct: 1195 NEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN----KVFLLKGIMEALSK 1250
Query: 1278 SASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECK 1337
S LFEV VPDYKQL+ C +EV LKELWD + +V +SI W+TT W++INVE M+++CK
Sbjct: 1251 SGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCK 1310
Query: 1338 QFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSF 1397
+FA+ +R+LDKE++ WDAF GL++TV N ++SLRAV+ELQNPAIRERHW+QLMQAT V F
Sbjct: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370
Query: 1398 TMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRT 1457
M ++TTLA LLQL LH YEDEVR IVDKA KE GMEK LK L +TW+ MEFQ+EPHPRT
Sbjct: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430
Query: 1458 NVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQR 1517
+L S E L+E LEDNQVQLQNL+MSKY+A FL+EV+ WQ+KLST D+VISIWFEVQR
Sbjct: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490
Query: 1518 TWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLE 1577
TW+HLESIF GSEDIR QLP DS+RF+ I+ +FK L DA K PNVV+ T+KPGLY KLE
Sbjct: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
Query: 1578 DIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMA 1637
++ L +CEKALAEYL+TKRLAFPRFYF+SS+DLLDILSNG P +V RHLSKLFD++
Sbjct: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610
Query: 1638 KMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTE 1697
K++F+LDAS +P K LGMYSKE+EY+ F + CD SGQVE+WLN VL M +T+RHE+ E
Sbjct: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670
Query: 1698 GVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL 1757
V YEEKPREQW+ D+PAQ IWWTTEVG+AFARLEEGYE+A+KDY KKQ++QL
Sbjct: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNKKQISQL 1723
Query: 1758 KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE 1817
LIT+LIG L+ GDR KIMTICTIDVHARDVVAKMI V+++QAF W +QLRHRWD+E
Sbjct: 1724 NVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEE 1780
Query: 1818 VKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKT 1877
+HCFANICDAQ YSYEYLGNTPRLVITPLTDRCYITLTQSLHL M GAPAGPAGTGKT
Sbjct: 1781 KRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKT 1840
Query: 1878 ETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAV 1937
ETTKDLGRALG +VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSV+AV
Sbjct: 1841 ETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAV 1900
Query: 1938 QVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVV 1997
QVK +QDAIR KK+ F+FLGE I L P+VGIFITMNPGYAGR ELPENLK+LFRPCAMVV
Sbjct: 1901 QVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVV 1960
Query: 1998 PDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2057
PDFELICEIML+AEGF+EA+ LARKFITLY LCKELLSKQDHYDWGLRAIKSVLVVAGSL
Sbjct: 1961 PDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2020
Query: 2058 KRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRK 2117
KRGDP R EDQVLMR+LRDFNIPKIVTDD+P+FMGLIGDLFPALDVPR+RD NFE ++++
Sbjct: 2021 KRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQ 2080
Query: 2118 AIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVW 2177
+IV+LKLQAED+FVLKVVQLEELL VRHSVF+VG AG+GKSQVL+SL+KTYQ +KR+PV
Sbjct: 2081 SIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVA 2140
Query: 2178 TDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIES 2237
DL+PKAVT DELFGIINP T EWKDGLFS+IMR+LANITHDGPKWI+LDGDIDPMWIES
Sbjct: 2141 VDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIES 2200
Query: 2238 LNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPP 2297
LNTVMDDNKVLTLASNERIPLN TM+L+FEISHLRTATPATVSRAGILYINPADLGWNP
Sbjct: 2201 LNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPV 2260
Query: 2298 VSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLT 2357
VSSWIE+R++Q+E+ANL ILFDKYLPTCLD LR FKKI P+PE +++Q + +LLECLLT
Sbjct: 2261 VSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLT 2320
Query: 2358 TEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTI 2417
+ +P D P+E+YE YFVF WAFGGAM QDQLVDYR EFSKWW+ EFKT+KFPSQGTI
Sbjct: 2321 EKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTI 2380
Query: 2418 FDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLV 2477
FDYYIDP+TKKF PW+ VP FE DP++PLQA LVHT+ETIR+ YFM+ LM + PVMLV
Sbjct: 2381 FDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLV 2440
Query: 2478 GTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGN 2537
G AGTGKSVL+G KL SL+ + YLV+ VPFN+YTTSAMLQ VLEKPLEKK+GRNYGPPG
Sbjct: 2441 GNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT 2500
Query: 2538 KKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTA 2597
KKL+YFIDDMNMPEVD YGTV PHT+IRQH+D+ HWYDR KL+LK+I N QYV+CMNPT+
Sbjct: 2501 KKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS 2560
Query: 2598 GSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALA 2657
GSFTI+ RLQRHF VF +SFPG +AL++IY+ ILTQHL + ++Q+ L+ ALA
Sbjct: 2561 GSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALA 2620
Query: 2658 FHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRD 2717
HQKI TFLPT IKFHY+FNLRD +NIFQG+LFS+ E +K+ DL+RL+LHE+ RVY D
Sbjct: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680
Query: 2718 KMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELL 2777
KMV+EKD + ++ KK FDD+ D + + PN++CHFA GIG+PKY+PV L
Sbjct: 2681 KMVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPKYVPVTDMAPL 2739
Query: 2778 TQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRL 2837
+ LV+ L+++NEVN VM+LVLFEDA+ H+C INRILESPRGNALLVGVGGSGKQSL+RL
Sbjct: 2740 NKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799
Query: 2838 AAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLIN 2897
AA+IS +DVFQITL+KGY I D K+DLA+ +KA VKN+ +VFLMTD+QVA+E+FLVLIN
Sbjct: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859
Query: 2898 DLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSP 2957
DLLASGEIP L+ +DEVENIIS++R +VKS G+ D RE CWKFFI+++RRQLKV LCFSP
Sbjct: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSP 2919
Query: 2958 VGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAF 3017
VG+ LRVR+RKFPA+VNCTAI WFHEWP+ AL SVS RFL+ TEGI VK SIS FM++
Sbjct: 2920 VGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSY 2979
Query: 3018 VHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLH 3077
VHT+VN+ S+ YL+ E+RYNYTTPK+FLE I+LYQ+LL + R EL K ERLENGL+KL
Sbjct: 2980 VHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQ 3039
Query: 3078 STSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIML 3137
ST++QVDDLKAKLA QE ELKQKNE AD+LIQVVG+E +KVS+EKA+AD+EE KV VI
Sbjct: 3040 STASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINK 3099
Query: 3138 EVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMA 3197
V +KQK CE DLAKAEPAL AAQ AL+TLNK NLTELKSFGSPP AV NV+AAVM+L A
Sbjct: 3100 NVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTA 3159
Query: 3198 PRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVAT 3257
P G++PKD+SWKAAK+ M KVD FLDSL F+KE+I E CLKA +PY +P F+PEF+ +
Sbjct: 3160 PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRS 3219
Query: 3258 KSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENL 3317
KS AAAGLCSW INIVRFYEV+CDV PKRQAL +A A+L AQEKL+ IK KIA LN NL
Sbjct: 3220 KSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANL 3279
Query: 3318 AKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLC 3377
+ LT+ FEKATA+K+KCQQEA+ T I LANRLVGGLASEN+RWA++V+NF+ Q TLC
Sbjct: 3280 SNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLC 3339
Query: 3378 GDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAA 3437
GD+LLI+AF+SY+G+FTKKYR L+++ W PY+ LK PIP+T LDPL +L DDADVA
Sbjct: 3340 GDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVAT 3399
Query: 3438 WQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIGQKGYLQI 3497
W N+GLP+DRMS ENATIL N ERWPL+VD QLQGIKWIKNKY +L+ ++GQK YL +
Sbjct: 3400 WNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDV 3459
Query: 3498 IEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTKL 3557
IEQA+ G +LIEN+ E++DPVL PLLGR IKKG++IKIGDKE EY+PKFRLILHTK
Sbjct: 3460 IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKY 3519
Query: 3558 ANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLK 3617
NPHY+PE+QAQ TLINF VTRDGLEDQLLAAVV+ ERPDLEQLK++LTK QN FKI LK
Sbjct: 3520 FNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLK 3579
Query: 3618 TLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRP 3677
LEDSLL+RLS+ASGNFLG+T LVENLE TK TA+E+E+KV EAK+TEVKINEARE+YRP
Sbjct: 3580 ELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRP 3639
Query: 3678 AAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFS 3737
AA RASLLYFI+NDL+KI+P+YQFSLKAF++VF+KA++R P +++RV NL D IT+S
Sbjct: 3640 AAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYS 3699
Query: 3738 VYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQA 3797
VY YT RGLFE DKL +LAQ+TFQ+L M +E+N VELDFLLR P + G SPV+FL HQ
Sbjct: 3700 VYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQG 3759
Query: 3798 WGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAM 3857
WG +K LS M+EF NLD DIEGSAK WKK VESE PEKE P+EWKNKTALQ+LCM+R +
Sbjct: 3760 WGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCL 3819
Query: 3858 RPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQG 3917
RPDRMTYA+++FVEEK+GSK+V GR+++F+ S+EES P+T +FFILSPGVDPLKDVE+ G
Sbjct: 3820 RPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG 3879
Query: 3918 RKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQ--------NIHLVAKWLS 3969
+KLG+T +N HNVSLGQGQEVVAE ALD+AA+KGHWVILQ NIHLVA+WL
Sbjct: 3880 KKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLG 3939
Query: 3970 TLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA 4029
TL+KKLE +S SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTGMHANLHKA
Sbjct: 3940 TLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKA 3999
Query: 4030 LDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNV 4089
LD FTQDTLEMC++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN GDLTIS+NV
Sbjct: 4000 LDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINV 4059
Query: 4090 LYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG 4149
LYN+LEAN KVP+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLEG++ LAPG
Sbjct: 4060 LYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG 4119
Query: 4150 FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQA 4209
F +P N+DY GYH+YID LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE+QP+++ +
Sbjct: 4120 FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDS 4179
Query: 4210 RDGAGATREEK-----------------------------VKALLEEILERVTDEFNIPE 4240
G G +REEK VKA+L++ILE++ + FN+ E
Sbjct: 4180 GAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAE 4239
Query: 4241 LMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFD 4300
+MAK E+TPY+VVAFQEC RMNILT E++RSL+EL LGLKGELT+T+ +E+L AL++D
Sbjct: 4240 IMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYD 4299
Query: 4301 MVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIM 4360
VP++W RAYPS GLAAW+ DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIM
Sbjct: 4300 TVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIM 4359
Query: 4361 QSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKL 4420
QS ARKNEWPLD+M L ++TKKNRE+ +PPREG+Y++GLFMEGA WDTQ G+I EA+L
Sbjct: 4360 QSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARL 4419
Query: 4421 KDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGV 4480
K+LTP MPV+FIKAIP D+ + +++Y CPVYKT RGPTYVWTFNLKTKE +KW+LA V
Sbjct: 4420 KELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAV 4479
Query: 4481 ALLLQI 4486
ALLLQ+
Sbjct: 4480 ALLLQV 4485
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 5709 bits (14811), Expect = 0.0
Identities = 2804/4506 (62%), Positives = 3513/4506 (77%), Gaps = 67/4506 (1%)
Query: 22 DRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDAAEGPRPLLVVRPGPRGL 81
D RL L ++ L+ W + G+ E L F + + +LV+ G+
Sbjct: 6 DVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQ----VLVLTLNAAGM 61
Query: 82 AIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSEVV 141
I P L P+S +K ++F++T E D++R ++ GD+ P++ L A+ EV+
Sbjct: 62 II-PCLGF-PQS--LKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVL 117
Query: 142 LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201
+L +N WP ++ ED+ + H L+ ++ V+ ++KGKTLLP+P ++
Sbjct: 118 SSLLNQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLES 177
Query: 202 SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261
E + S+D +++AIE+ +I WS+Q++ VL ++S+Q LL G +P P+VE EFW +R +
Sbjct: 178 MERIPSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLN 237
Query: 262 LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321
LK I+ QL V + ++L+K +S Y+PA + +Y +V L EA DI ++L PL+ LE
Sbjct: 238 LKCIHEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLE 297
Query: 322 ALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPED 381
+E A+F + + +L +C IWAT + Y +P R+ V+LQE CN +I+ +LSPE+
Sbjct: 298 EMEQADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEE 357
Query: 382 LLRS---EVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVR 438
+L+ E+EE + + + L Q + N+ +FK+ + V W+F SSL F R
Sbjct: 358 VLKGLQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVP-WEFPSSLAFSR 416
Query: 439 LDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSS 498
++ F ++ +E L KTA++F KL K+E GVRGN L V ++++E E+ ++ +
Sbjct: 417 INSFFQRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKY 476
Query: 499 DCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLLERPL 558
D L ++F+ D ++F K++DLDRRL TIF Q FDD ++ + KLL + G L+ERPL
Sbjct: 477 DPLDPGDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPL 536
Query: 559 VARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELR 618
+ + + +Y V++++F+ +LD +++Y + E +HKNMP VAG L+W+ EL+
Sbjct: 537 ILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQ 596
Query: 619 QRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNL 678
+R++ + + HP M AE K QKY++M+ LL + ++Y+ W V + +NL
Sbjct: 597 ERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNL 656
Query: 679 SQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVAN 738
QPL+ RD + I +NF+ L++VL+E+ YL ++ K +P++A ++FS + +R+ V N
Sbjct: 657 GQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGN 716
Query: 739 LELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIH 798
LEL+ WYN++ + VEF L++ EL+ ID++L +AE TL W EG+ Y+ E+ +H
Sbjct: 717 LELIVGWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILH 776
Query: 799 DLEQRIQKTKDNVEEIQNIMKTW-VTPIFKTKDGKRESLLSLDDRHDRMEKYYNLIKESG 857
+L+ R+QK K N+E I MK W P+F+ KD K+E+LL LD R + K Y ++++G
Sbjct: 777 NLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAG 836
Query: 858 LKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSLKYLLENTECKAGLT 917
+KI A+V EN LF AD S WK YV ID+++L+ F I SL +L++N +
Sbjct: 837 VKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIA 896
Query: 918 PIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQV 977
P+FE ++ L L F P+LE G GF ++EGL+ I+ + L+PRL+ +Y++
Sbjct: 897 PLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAKDR--MNYKM 954
Query: 978 DLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHILTP 1037
DL+ DL MR + V M YQ +F +YSYL+ ++ +E + FL+YG +T
Sbjct: 955 DLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTA 1014
Query: 1038 EEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLL 1097
E+++ +D IP+ PP L+QF+ QIDSYE LYEEV + E KVF GW++ D RPFK +LL
Sbjct: 1015 EDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALL 1074
Query: 1098 NIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKE 1157
+ I+RW +FK+HL +HVT+SLA+L+AF+K + GL K +++GD+ GLVE+MGHLM VKE
Sbjct: 1075 STIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKE 1134
Query: 1158 RQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQA 1217
RQ+ TD MFEPLKQTIELLKTY +E+PE + +L+ELPE W N KK+AI VK VAPLQA
Sbjct: 1135 RQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQA 1194
Query: 1218 NEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISE 1277
NEV++LR++C F+ +Q +F E+F +EAPF F +P++ L+ ++ ++ M ++S+
Sbjct: 1195 NEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLN----KVFLLKGIMEALSK 1250
Query: 1278 SASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECK 1337
S LFEV VPDYKQL+ C +EV LKELWD + +V +SI W+TT W++INVE M+++CK
Sbjct: 1251 SGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCK 1310
Query: 1338 QFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSF 1397
+FA+ +R+LDKE++ WDAF GL++TV N ++SLRAV+ELQNPAIRERHW+QLMQAT V F
Sbjct: 1311 KFAKDMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370
Query: 1398 TMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRT 1457
M ++TTLA LLQL LH YEDEVR IVDKA KE GMEK LK L +TW+ MEFQ+EPHPRT
Sbjct: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430
Query: 1458 NVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQR 1517
+L S E L+E LEDNQVQLQNL+MSKY+A FL+EV+ WQ+KLST D+VISIWFEVQR
Sbjct: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490
Query: 1518 TWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLE 1577
TW+HLESIF GSEDIR QLP DS+RF+ I+ +FK L DA K PNVV+ T+KPGLY KLE
Sbjct: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
Query: 1578 DIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMA 1637
++ L +CEKALAEYL+TKRLAFPRFYF+SS+DLLDILSNG P +V RHLSKLFD++
Sbjct: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610
Query: 1638 KMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTE 1697
K++F+LDAS +P K LGMYSKE+EY+ F + CD SGQVE+WLN VL M +T+RHE+ E
Sbjct: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670
Query: 1698 GVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQL 1757
V YEEKPREQW+ D+PAQ IWWTTEVG+AFARLEEGYE+A++DY KKQ++QL
Sbjct: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIRDYNKKQISQL 1723
Query: 1758 KTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDE 1817
LIT+L+G L+ GDR KIMTICTIDVHARDVVAKMI V+++QAF W +QLRHRWD+E
Sbjct: 1724 NVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMI---VESSQAFTWQAQLRHRWDEE 1780
Query: 1818 VKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKT 1877
+HCFANICDAQ YSYEYLGNTPRLVITPLTDRCYITLTQSLHL M GAPAGPAGTGKT
Sbjct: 1781 KRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTGKT 1840
Query: 1878 ETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAV 1937
ETTKDLGRALG +VYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSV+AV
Sbjct: 1841 ETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVIAV 1900
Query: 1938 QVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVV 1997
QVK +QDAIR KK+ F+FLGE I L P+VGIFITMNPGYAGR ELPENLK+LFRPCAMVV
Sbjct: 1901 QVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAMVV 1960
Query: 1998 PDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2057
PDFELICEIML+AEGF+EA+ LARKFITLY LCKELLSKQDHYDWGLRAIKSVLVVAGSL
Sbjct: 1961 PDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSL 2020
Query: 2058 KRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRK 2117
KRGDP R EDQVLMR+LRDFNIPKIVTDD+P+FMGLIGDLFPALDVPR+RD NFE ++++
Sbjct: 2021 KRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKIIKQ 2080
Query: 2118 AIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVW 2177
+IV+LKLQAED+FVLKVVQLEELL VRHSVF+VG AG+GKSQVL+SL+KTYQ +KR+PV
Sbjct: 2081 SIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKPVA 2140
Query: 2178 TDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIES 2237
DL+PKAVT DELFGIINP T EWKDGLFS+IMR+LANITHDGPKWI+LDGDIDPMWIES
Sbjct: 2141 VDLDPKAVTCDELFGIINPVTREWKDGLFSTIMRDLANITHDGPKWIILDGDIDPMWIES 2200
Query: 2238 LNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPP 2297
LNTVMDDNKVLTLASNERIPLN TM+L+FEISHLRTATPATVSRAGILYINPADLGWNP
Sbjct: 2201 LNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILYINPADLGWNPV 2260
Query: 2298 VSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLT 2357
VSSWIE+R++Q+E+ANL ILFDKYLPTCLD LR FKKI P+PE +++Q + +LLECLLT
Sbjct: 2261 VSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQTILYLLECLLT 2320
Query: 2358 TEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFPSQGTI 2417
+ +P D P+E+YE YFVF WAFGGAM QDQLVDYR EFSKWW+ EFKT+KFPSQGTI
Sbjct: 2321 EKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEFKTIKFPSQGTI 2380
Query: 2418 FDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLV 2477
FDYYIDP+TKKF PW+ VP FE DP++PLQA LVHT+ETIR+ YFM+ LM + PVMLV
Sbjct: 2381 FDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDLLMEKSWPVMLV 2440
Query: 2478 GTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGN 2537
G AGTGKSVL+G KL SL+ + YLV+ VPFN+YTTSAMLQ VLEKPLEKK+GRNYGPPG
Sbjct: 2441 GNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGT 2500
Query: 2538 KKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTA 2597
KKL+YFIDDMNMPEVD YGTV PHT+IRQH+D+ HWYDR KL+LK+I N QYV+CMNPT+
Sbjct: 2501 KKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHNCQYVACMNPTS 2560
Query: 2598 GSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALA 2657
GSFTI+ RLQRHF VF +SFPG +AL++IY+ ILTQHL + ++Q+ L+ ALA
Sbjct: 2561 GSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQRISSQLVAAALA 2620
Query: 2658 FHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRD 2717
HQKI TFLPT IKFHY+FNLRD +NIFQG+LFS+ E +K+ DL+RL+LHE+ RVY D
Sbjct: 2621 LHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRLWLHETERVYGD 2680
Query: 2718 KMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELL 2777
KMV+EKD + ++ KK FDD+ D + + PN++CHFA GIG+PKY+PV L
Sbjct: 2681 KMVDEKDQETLHRVTMASTKKFFDDLGDELLFAK-PNIFCHFAQGIGDPKYVPVTDMAPL 2739
Query: 2778 TQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRL 2837
+ LV+ L+++NEVN VM+LVLFEDA+ H+C INRILESPRGNALLVGVGGSGKQSL+RL
Sbjct: 2740 NKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVGGSGKQSLSRL 2799
Query: 2838 AAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLIN 2897
AA+IS +DVFQITL+KGY I D K+DLA+ +KA VKN+ +VFLMTD+QVA+E+FLVLIN
Sbjct: 2800 AAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQVAEEQFLVLIN 2859
Query: 2898 DLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSP 2957
DLLASGEIP L+ +DEVENIIS++R +VKS G+ D RE CWKFFI+++RRQLKV LCFSP
Sbjct: 2860 DLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRRQLKVILCFSP 2919
Query: 2958 VGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAF 3017
VG+ LRVR+RKFPA+VNCTAI WFHEWP+ AL SVS RFL+ TEGI VK SIS FM++
Sbjct: 2920 VGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEVKASISFFMSY 2979
Query: 3018 VHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLH 3077
VHT+VN+ S+ YL+ E+RYNYTTPK+FLE I+LYQ+LL + R EL K ERLENGL+KL
Sbjct: 2980 VHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIERLENGLMKLQ 3039
Query: 3078 STSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIML 3137
ST++QVDDLKAKLA QE ELKQKNE AD+LIQVVG+E +KVS+EKA+AD+EE KV VI
Sbjct: 3040 STASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQEEVKVEVINK 3099
Query: 3138 EVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMA 3197
V +KQK CE DLAKAEPAL AAQ AL+TLNK NLTELKSFGSPP AV NV+AAVM+L A
Sbjct: 3100 NVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVNVTAAVMILTA 3159
Query: 3198 PRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVAT 3257
P G++PKD+SWKAAK+ M KVD FLDSL F+KE+I E CLKA +PY +P F+PEF+ +
Sbjct: 3160 PGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKPYQGNPTFDPEFIRS 3219
Query: 3258 KSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENL 3317
KS AAAGLCSW INIVRFYEV+CDV PKRQAL +A A+L AQEKL+ IK KIA LN NL
Sbjct: 3220 KSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRIKNKIAELNANL 3279
Query: 3318 AKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLC 3377
+ LT+ FEKATA+K+KCQQEA+ T I LANRLVGGLASEN+RWA++V+NF+ Q TLC
Sbjct: 3280 SNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESVENFRSQGVTLC 3339
Query: 3378 GDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAA 3437
GD+LLI+AF+SY+G+FTKKYR L+++ W PY+ LK PIP+T LDPL +L DDADVA
Sbjct: 3340 GDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPLSLLTDDADVAT 3399
Query: 3438 WQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIGQKGYLQI 3497
W N+GLP+DRMS ENATIL N ERWPL+VD QLQGIKWIKNKY +L+ ++GQK YL +
Sbjct: 3400 WNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKAIRLGQKSYLDV 3459
Query: 3498 IEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTKL 3557
IEQA+ G +LIEN+ E++DPVL PLLGR IKKG++IKIGDKE EY+PKFRLILHTK
Sbjct: 3460 IEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYHPKFRLILHTKY 3519
Query: 3558 ANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLK 3617
NPHY+PE+QAQ TLINF VTRDGLEDQLLAAVV+ ERPDLEQLK++LTK QN FKI LK
Sbjct: 3520 FNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLTKSQNEFKIVLK 3579
Query: 3618 TLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRP 3677
LEDSLL+RLS+ASGNFLG+T LVENLE TK TA+E+E+KV EAK+TEVKINEARE+YRP
Sbjct: 3580 ELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEVKINEARENYRP 3639
Query: 3678 AAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFS 3737
AA RASLLYFI+NDL+KI+P+YQFSLKAF++VF+KA++R P +++RV NL D IT+S
Sbjct: 3640 AAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQRVINLTDEITYS 3699
Query: 3738 VYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQA 3797
VY YT RGLFE DKL +LAQ+TFQ+L M +E+N VELDFLLR P + G SPV+FL HQ
Sbjct: 3700 VYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGVVSPVDFLQHQG 3759
Query: 3798 WGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAM 3857
WG +K LS M+EF NLD DIEGSAK WKK VESE PEKE P+EWKNKTALQ+LCM+R +
Sbjct: 3760 WGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKTALQKLCMVRCL 3819
Query: 3858 RPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQG 3917
RPDRMTYA+++FVEEK+GSK+V GR+++F+ S+EES P+T +FFILSPGVDPLKDVE+ G
Sbjct: 3820 RPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPGVDPLKDVEALG 3879
Query: 3918 RKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQ--------NIHLVAKWLS 3969
+KLG+T +N HNVSLGQGQEVVAE ALD+AA+KGHWVILQ NIHLVA+WL
Sbjct: 3880 KKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHCRNIHLVARWLG 3939
Query: 3970 TLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA 4029
TL+KKLE +S SH ++RVF+SAEPAPSPE HIIPQGILEN+IKITNEPPTGMHANLHKA
Sbjct: 3940 TLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEPPTGMHANLHKA 3999
Query: 4030 LDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNV 4089
LD FTQDTLEMC++E EFK +LFALCYFHAVVAERRKFG QGWNRSYPFN GDLTIS+NV
Sbjct: 4000 LDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPFNNGDLTISINV 4059
Query: 4090 LYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG 4149
LYN+LEAN KVP+DDLRYLFGEIMYGGHITDDWDRRLCRTYL E+IR EMLEG++ LAPG
Sbjct: 4060 LYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTEMLEGDVLLAPG 4119
Query: 4150 FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQA 4209
F +P N+DY GYH+YID LPPESPYLYGLHPNAEIGFLT TSEKLFRTVLE+QP+++ +
Sbjct: 4120 FQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRTVLEMQPKETDS 4179
Query: 4210 RDGAGATREEK-----------------------------VKALLEEILERVTDEFNIPE 4240
G G +REEK VKA+L++ILE++ + FN+ E
Sbjct: 4180 GAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDILEKIPETFNMAE 4239
Query: 4241 LMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFD 4300
+MAK E+TPY+VVAFQEC RMNILT E++RSL+EL LGLKGELT+T+ +E+L AL++D
Sbjct: 4240 IMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYD 4299
Query: 4301 MVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIM 4360
VP++W RAYPS GLAAW+ DLL RI+ELEAWT DF +P+TVWL GFFNPQSFLTAIM
Sbjct: 4300 TVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIM 4359
Query: 4361 QSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKL 4420
QS ARKNEWPLD+M L ++TKKNRE+ +PPREG+Y++GLFMEGA WDTQ G+I EA+L
Sbjct: 4360 QSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARL 4419
Query: 4421 KDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGV 4480
K+LTP MPV+FIKAIP D+ + +++Y CPVYKT RGPTYVWTFNLKTKE +KW+LA V
Sbjct: 4420 KELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAV 4479
Query: 4481 ALLLQI 4486
ALLLQ+
Sbjct: 4480 ALLLQV 4485
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 5373 bits (13938), Expect = 0.0
Identities = 2661/4499 (59%), Positives = 3401/4499 (75%), Gaps = 33/4499 (0%)
Query: 5 EERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDA 64
EE AA D R+R LG +AM L W + S + Q+L FL
Sbjct: 39 EENEEEAAARRARSFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFL---- 94
Query: 65 AEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGD 124
E P +V + E+ + A K +F + E G + F V+ G+
Sbjct: 95 -ESTSPACLVFSFAASGRLAASQEIPRD---ANHKLVFISKKITESIGVNDFSQVVLFGE 150
Query: 125 LPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKT 184
LPA L H++A E+++PVL+N+ N +W +D+ H ++ + + ++ +T
Sbjct: 151 LPALSLGHVSAFLDEILVPVLSNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRT 210
Query: 185 LLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGE 244
LLP+P + KM+ + SE S ++ +++AIES VI+WS+Q+Q +++R+S Q LL G
Sbjct: 211 LLPIPTVAGKMDLDQNCSENKPPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGL 270
Query: 245 NPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALA 304
+ +P+ EL+FW R E+L IY+QL+ V M K+L QSSYFP K ++ V AL
Sbjct: 271 HLSPQAELDFWMMRRENLSCIYDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALL 330
Query: 305 EAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQE 364
EAQD+ ++L PL+RH++ L+ EFP+ + + PL H +CLIW+ K Y +P R+ VLLQE
Sbjct: 331 EAQDVELYLRPLRRHIQCLQETEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQE 390
Query: 365 ICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQE 424
CNL I QA+ YLSPEDLLR E+EES K+QV + L FK F + R+ L +YF ++
Sbjct: 391 FCNLFINQATAYLSPEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFM-GRK 449
Query: 425 VKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHE 484
++ WDFQS LVF R D FL +L +E + T L+F KL ++EF G +G L+ QV +M E
Sbjct: 450 LRPWDFQSHLVFCRFDKFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSE 509
Query: 485 EFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAF 544
E E+ +L S+ D + +FE+D F K + DRRLGTI +AF + GLE AF
Sbjct: 510 ELMELCKLFKQSTYDPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAF 569
Query: 545 KLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNM 604
KLL I GN LE+P+V S Y L+ MFN +LD + +Y++H+++ E G ++KNM
Sbjct: 570 KLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHMKQ-IECGHVVLNKNM 628
Query: 605 PTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYE 664
P +G ++WAQ++ QR+Q +SNF + + + + + + QKY +M +LL+++E+R+Y
Sbjct: 629 PFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYN 688
Query: 665 DWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAA 724
+W V E ++NL+QPL+K + +NF+P+L++VL+E+ YL + + +P++A A
Sbjct: 689 EWKSNVDEICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALA 748
Query: 725 MFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTE 784
+F R+ + + NL+L+ YNK+ +TLLEVE+PL+E+EL+ ID +L AA L W+ +
Sbjct: 749 IFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD 808
Query: 785 GICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTK-DGKRESLLSLDDRH 843
Y+ + ++ +LE R+++T+ NV+ IQ M+ W + + + +RE+ +L+D+
Sbjct: 809 -CWGYIERVRAATSELEHRVERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKG 867
Query: 844 DRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSL 903
D K Y LI+ G KIH LV+EN LF A+P+ + WK YV ID++++ GFF AI L
Sbjct: 868 DLFTKKYKLIQGDGCKIHNLVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDL 927
Query: 904 KYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLV 963
+ L+NTE + P F+AQ+ L PE+VF PSL+ GF D+VE ++ + FR+ + +
Sbjct: 928 DFFLKNTEKQLKPAPFFQAQMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQM 987
Query: 964 PRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKE 1023
R++ +YQ D+D + LA +R+ +M RV ++ +++T ++YL+V+DR E
Sbjct: 988 NRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAE 1047
Query: 1024 VLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDG 1083
+ FLLYGH ++ +E++ H + IPE PP L QFK QID YE LY ++ + E +VFD
Sbjct: 1048 FMKHFLLYGHAVSSDEMDAHANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDS 1107
Query: 1084 WMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQ 1143
W K+D++PFK SLL IIK+WS +F++HL+ V SL L FIK+++SGL +++ +GD
Sbjct: 1108 WFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHD 1167
Query: 1144 GLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKK 1203
GLV+IM HL+AV+ RQ TDE+FEPLK+TI LL++Y Q++PE V+ QLEELPE+W KK
Sbjct: 1168 GLVDIMVHLLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKK 1227
Query: 1204 VAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHI 1263
+A TV+ +V+PL EVTL+R++C FDA+Q +F E+F AP F++ +P+ LD +
Sbjct: 1228 IAATVRHEVSPLHNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANE 1287
Query: 1264 EIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTP 1323
E++ +E M + ES LFEV +P+YKQ++QCRKE+ LK LWD I V SI W T
Sbjct: 1288 ELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQ 1347
Query: 1324 WRNINVEAMELECKQFAR-----HIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQN 1378
WR I+VE M++E ++FA+ I +L+KEVR WDA+TGLE TV + +SLRA+ ELQ+
Sbjct: 1348 WRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQS 1407
Query: 1379 PAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLK 1438
PA+R+RHW QLM+A GV F +++ TTLA LL L+LH ED+VR IVDKA KE+G EK +
Sbjct: 1408 PALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVIT 1467
Query: 1439 ELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGW 1498
E+ TWA M+F YE H RT +PLL SDE L E LE NQVQLQ L+ SKYV +F+E+V W
Sbjct: 1468 EISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSW 1527
Query: 1499 QKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQ 1558
Q KL+ D VI W EVQRTW+HLESIF SEDIR QL +D++RF+G+D +FKEL +
Sbjct: 1528 QNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTA 1587
Query: 1559 KIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSN 1618
K+ NV++ T +P LYEKL+D+Q RL LCEKALAEYL+TKR+AFPRFYF+SS+DLLDILS
Sbjct: 1588 KVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSK 1647
Query: 1619 GTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEI 1678
G P+QV HL+KLFD++A ++F+ D ++GMYSKE+EYV F C+C G VE
Sbjct: 1648 GAQPKQVTCHLAKLFDSIADLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVET 1706
Query: 1679 WLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARL 1738
WL + M+ TVRH +TE + AYEEKPRE W+FD PAQVALT +QIWWTT+VG+AF+RL
Sbjct: 1707 WLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRL 1766
Query: 1739 EEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQK- 1797
EEGYE+A+KD++KKQ++QL TLIT+L+G+L GDRQKIMTICTIDVHARDVVAK+I+QK
Sbjct: 1767 EEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQ 1826
Query: 1798 -VDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITL 1856
V + QAF WLSQLRHRW+D KHCF NICDAQF Y YEYLGN+PRLVITPLTDRCYITL
Sbjct: 1827 VVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITL 1886
Query: 1857 TQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTG 1916
TQSLHLTMSGAPAGPAGTGKTETTKDLGRALG++VYVFNCSEQMDYKS GNIYKGL QTG
Sbjct: 1887 TQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTG 1946
Query: 1917 AWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGY 1976
AWGCFDEFNRISVEVLSVVAVQVK I DAIR++K+ F FLGE I+L PSVGIFITMNPGY
Sbjct: 1947 AWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGY 2006
Query: 1977 AGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSK 2036
AGRTELPENLK+LFRPCAMV PD ELICEI+LVAEGF++A++LARKFITLY LCKELLSK
Sbjct: 2007 AGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSK 2066
Query: 2037 QDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGD 2096
QDHYDWGLRAIKSVLVVAGSLKRGD +RPEDQVLMR+LRDFN+PKIVTDD+P+F+GL+GD
Sbjct: 2067 QDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGD 2126
Query: 2097 LFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTG 2156
LFPALDVPRRR +FE +VR++ ++L+LQ E++F+LKVVQLEELLAVRHSVFVVG AGTG
Sbjct: 2127 LFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTG 2186
Query: 2157 KSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDG---------LFS 2207
KS++LR+L++TY MK++PVW DLNPKAVT DELFG I+ AT EWKDG LFS
Sbjct: 2187 KSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFS 2246
Query: 2208 SIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFE 2267
SI+RE AN+ HDGPKWI+LDGDIDPMWIESLNTVMDDNKVLTLASNERI L P M+LLFE
Sbjct: 2247 SILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFE 2306
Query: 2268 ISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLD 2327
I HLR+ATPATVSRAGILY+NP DLGWNP V+SWI++R Q+E+ANLTILFDKY+P CLD
Sbjct: 2307 IHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLD 2366
Query: 2328 TLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMV 2387
LRT FK I IPE S+VQ +C LLECLLT E++P+D PKE+YE YFVFA IWAFGG ++
Sbjct: 2367 KLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLL 2426
Query: 2388 QDQLVDYRAEFSKWWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPL 2447
QDQ+ DY+A+FS+WW E K VKFPSQGTIFDYY+D +TKK PW+ + QF DP++PL
Sbjct: 2427 QDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPL 2486
Query: 2448 QACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPF 2507
Q LVHT+ET R+ YFME L+ + +P+MLVG AG GK+V VG LASL E Y+V VPF
Sbjct: 2487 QTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLS-EDYIVSRVPF 2545
Query: 2508 NYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQH 2567
NYYTTS LQ +LEKPLEKKAG NYGP GNKKLIYFIDDMNMPEVD YGTVQPHT+IRQH
Sbjct: 2546 NYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQH 2605
Query: 2568 LDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIY 2627
+DYGHWYDR K+ LKEI N QYV+CMNP GSFTINPRLQRHF+VF +FP DAL++IY
Sbjct: 2606 IDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIY 2665
Query: 2628 SIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQ 2687
I + H + F S+ +S P LI +AFHQ + FLPT IKFHYIFNLRD +N+FQ
Sbjct: 2666 GQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQ 2725
Query: 2688 GILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPV 2747
GILF+S EC+K DLI L+LHES RVY DK++++KD DLF + E K F+ I+ +
Sbjct: 2726 GILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHM 2785
Query: 2748 EQTQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHV 2807
Q P +YCHFA+ +P YMPV+ WE+L L E L+N+NE+N M LVLFEDAM+HV
Sbjct: 2786 -LLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHV 2844
Query: 2808 CHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASL 2867
C I+RIL +P+G ALLVGVGGSGKQSL+RLAA++ ++VFQITL +GY IQ+ ++DLA+L
Sbjct: 2845 CRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANL 2904
Query: 2868 CLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKS 2927
++ G KN+ TVFL+TDAQV DE FLVLINDLLASGEIPDL+SD++V+ IIS + NEV +
Sbjct: 2905 YIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHA 2964
Query: 2928 QGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQ 2987
G+VD+RENCWKFF+ R+R QLK+ LCFSPVG LRVR+RKFPAIVNCTAI WFH WPQ+
Sbjct: 2965 LGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQE 3024
Query: 2988 ALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEF 3047
AL SVS RF++ T+GIEP K SIS FMA VHT+VN+ S Y NE+R+NYTTPKSFLE
Sbjct: 3025 ALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQ 3084
Query: 3048 IRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKL 3107
I L+++LL + + E+ K ERL NG+ KL +T++QV DLKA+LA+QE EL+ +N DA+ L
Sbjct: 3085 ISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEAL 3144
Query: 3108 IQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTL 3167
I +G++T+KVSREK +AD EE+KV I EV QKQ++CE DL KAEPAL AA AALNTL
Sbjct: 3145 ITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTL 3204
Query: 3168 NKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLIN 3227
N+ NL+ELK+F +PP+AV+NV+AAVMVL+APRGRVPKDRSWKAAKV M KVD FL +LIN
Sbjct: 3205 NRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALIN 3264
Query: 3228 FNKENIHENCLKAIRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKR 3286
++KE+I ENCLK + YL+DPEFNP + TKS+AAAGLC+WVINI++FYEV+CDVEPKR
Sbjct: 3265 YDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKR 3324
Query: 3287 QALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTIS 3346
QAL +A +L AA EKL AI+ K+ L+ NL++LTA FEKATA+K++CQ+E T TI
Sbjct: 3325 QALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIK 3384
Query: 3347 LANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTW 3406
LANRLV L ++ +RW ++++F+ QE+TLCGD+LL AF+SY+G FT++YRQ L+ W
Sbjct: 3385 LANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKW 3444
Query: 3407 RPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMV 3466
P+L Q K IP+T LD + ML DDA +AAW NEGLP+DRMS ENA IL +CERWPL++
Sbjct: 3445 VPFLQQ-KVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVI 3503
Query: 3467 DPQLQGIKWIKNKYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLG 3526
DPQ QGIKWIKNKYG DL+VT +GQKG+L IE AL G V+LIENLEE+IDPVL PLLG
Sbjct: 3504 DPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLG 3563
Query: 3527 REVIKKGRFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQL 3586
R IKKG++I+IGDKECE+N FRLILHTKLANPHY+PELQAQ TL+NFTVT DGLE QL
Sbjct: 3564 RNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQL 3623
Query: 3587 LAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEI 3646
LA VVS+ERPDLE+LK LTK QN FKI LK LED LL RLS+A G+FL +T LVE LE
Sbjct: 3624 LAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEA 3683
Query: 3647 TKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAF 3706
TK T AE+E KV EAK E KINEARE YRP AARASLLYF++NDL KI+P+YQFSLKAF
Sbjct: 3684 TKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAF 3743
Query: 3707 SIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMN 3766
+++F +A+E+A E ++ R++ L++SIT +V+ YT + LFE DKLT+L+Q+ FQILL
Sbjct: 3744 NVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRK 3803
Query: 3767 REVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKK 3826
+E++ +ELDFLLR V+ SPV+FL+ Q+W A+K ++ MEEF +DRD+EGSAK W+K
Sbjct: 3804 KEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRK 3863
Query: 3827 FVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDF 3886
+VESECPEKEKLPQEWK K+ +Q+L +LRAMRPDRMTYALR+FVEEKLG+KYV LD
Sbjct: 3864 WVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDL 3923
Query: 3887 ATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAAL 3946
+FEES PATP+FFILSPGVD LKD+E G++LG+T ++ FHNVSLGQGQE VAE AL
Sbjct: 3924 VKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVAL 3983
Query: 3947 DLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQG 4006
+ A+K GHWVILQN+HLVAKWL TLEK LE S+ SH ++RVFMSAE AP+P+ HIIPQG
Sbjct: 3984 EKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQG 4043
Query: 4007 ILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRK 4066
+LENSIKITNEPPTGM ANLH AL NF QDTLE+CS+E EFKSILF+LCYFHA VA R +
Sbjct: 4044 LLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLR 4103
Query: 4067 FGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRL 4126
FGPQGW+RSYPFN GDLTI +VLYN+LEAN+KVP++DLRYLFGEIMYGGHITDDWDR+L
Sbjct: 4104 FGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKL 4163
Query: 4127 CRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIG 4186
CR YL EF+ P + E EL LAPGF P +DY GYHQYI+ LPPESP LYGLHPNAEI
Sbjct: 4164 CRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIE 4223
Query: 4187 FLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVE 4246
FLT TS LFRT+LE+QPR++ + D G + EEKVK +L++ILE++ +EFN+ E+M K
Sbjct: 4224 FLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNS 4283
Query: 4247 ERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESW 4306
R+PY++V FQEC RMNIL REI+ SL +L+L LKGEL ++ +E Q AL +D VP++W
Sbjct: 4284 NRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTW 4343
Query: 4307 ARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARK 4366
++ AYPST GLA WF DLL R +EL+ WT D T+P+ VWL+GFFNPQSFLTAIMQ+ ARK
Sbjct: 4344 SKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARK 4403
Query: 4367 NEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPP 4426
NEWPLD+ L D+TKK +E++ PPREGAY+HGLFMEGA WDTQAG I EA+LK+L P
Sbjct: 4404 NEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACP 4463
Query: 4427 MPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQ 4485
MPV+F KA P D+Q+ + Y CPVY+T RGP+Y+WTF LK++E +KWVLAGVALLL+
Sbjct: 4464 MPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2314 bits (5997), Expect = 0.0
Identities = 1448/4447 (32%), Positives = 2374/4447 (53%), Gaps = 262/4447 (5%)
Query: 142 LPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSK 201
LP + E + +I ++ + ++ ++Q++G+ L +P S + E +D
Sbjct: 180 LPPMPGEAVEYHSIQLIRDEFLMNVQKFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLA 239
Query: 202 SETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYED 261
+ D + +E VI W Q+ ++ + + QG+ P E+EFW+ R
Sbjct: 240 A-------DPETVDILEQCVINWLNQISTAVEAQLKKTP-QGKGPL--AEIEFWRERNAT 289
Query: 262 LKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLE 321
L ++ Q + VR + ++ + S + ++ ++ EA D L ++R+ +
Sbjct: 290 LSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFK 349
Query: 322 ALENAE-FPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPE 380
+ + F V + ++ + ++W + Y R+ L++ I + ++ ++
Sbjct: 350 NITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLR 409
Query: 381 DLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVRLD 440
L + +Q K +TL +K+ + D R + +E++ W+F +F R D
Sbjct: 410 TLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIEASGREDR----WEFDRKRLFERTD 465
Query: 441 GFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDC 500
+ +L+ +F+ + E V G+ +++ + + + + D
Sbjct: 466 YMATICQDLSDVLQILEEFYNIFGPELKAVTGD--PKRIDDVLCRVDGLVTPMENLTFDP 523
Query: 501 LYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLLDIAGNLL-ERPLV 559
++S+ F V + K+E L + IF+Q ++ P ++ +AG + ER L
Sbjct: 524 FSIKSSQFWKYVMD-EFKIEVLIDIINKIFVQNLENPPLYKNH---PPVAGAIYWERSLF 579
Query: 560 ARDTSDKYLVL-IQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELR 618
R K+ +L Q + LD+ R QE++
Sbjct: 580 FR---IKHTILRFQEVQEILDSDR-------------------------------GQEVK 605
Query: 619 QRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNL 678
Q+ E R ++YED R YE W + +
Sbjct: 606 QKY-----------------LEVGRTMKEYED----------RKYEQWMEVTEQVLPALM 638
Query: 679 SQPLLKR------DPETKE----ITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSS 728
+ LL + +P T E INF+P L ++ E YLE +PE A +
Sbjct: 639 KKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINETKYLEQLGFT-VPELARNVALQ 697
Query: 729 RDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICD 788
D + + A ++ M + Y+ ++ TL + E L+++ Q + R+ + LNW + GI D
Sbjct: 698 EDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGD 757
Query: 789 YVTEITSSIHDLEQRIQKTKDNVEEIQN------IMKTWVTPIFKTKD---GKRESLLSL 839
Y+T +I E + + N ++I + + + P K+++ G +E +
Sbjct: 758 YITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINLFKYPAAKSEEELPGVKEFFEHI 817
Query: 840 DDRH----DRMEKYYNLIKESGLKIHAL-VQENLGLFSADPTSNIWKTYVNSIDNLLLNG 894
+ D M ++Y I K+ L V N G A ++ +K + I +L
Sbjct: 818 ERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNTG--KAPKLASYYKYWEKKIYEVL--- 872
Query: 895 FFLAIECSLKYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGF-C--DIVEG 951
+ LK L G P+F + L PE++ +P+ K F C + VE
Sbjct: 873 ----TKLILKNLQSFNSLILGNVPLFHTETILTAPEIILHPNTNEIDKMCFHCVRNCVEI 928
Query: 952 LITSIFRIPSLVPRLSPQNGSP------HYQVDLDGIPDLANMRRTLMERVQRMMGLCCG 1005
+ + PQ G ++ D+ P + + + V R++
Sbjct: 929 TKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNPQIIEQAVMIPQNVHRILINLMK 988
Query: 1006 YQSTFSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSY 1065
Y + +Y L+ D+ V+ +F + PP ++ + ++ Y
Sbjct: 989 YLQKWKRYRPLWKLDKAIVMEKF-------------------AAKKPPCVA-YDEKLQFY 1028
Query: 1066 ETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAF 1125
+ EV R P+ + +++ +R ++ K W + + L + L NL
Sbjct: 1029 SKIAYEVMR-HPLIKDEHCIRLQLRHLANTVQENAKSWVISLGKLLNESAKEELYNLHEE 1087
Query: 1126 IKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPE 1185
++ L K + L ++ + ++ + + + +++ + Y P+
Sbjct: 1088 MEHLAKNLRK--IPNTLEDLKFVLATIAEIRSKSLVMELRYRDVQERYRTMAMYNLFPPD 1145
Query: 1186 TVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEA 1245
+ ++++ W+N+ ++ V+ + ++ L R + + ++F ++F+ E
Sbjct: 1146 AEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELTRGEIMNYRVQIEEFAKRFYSEG 1205
Query: 1246 PFRF--DSIHPHQMLDARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLK 1303
P D ++L E+ + E + ++ + LF++ + Y +L + +KE+ L+
Sbjct: 1206 PGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKLFDLPITMYPELLKVQKEMSGLR 1265
Query: 1304 ELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTV 1363
+++ + + W T W N+NV+ ++ + F R +R L + VR LE+ +
Sbjct: 1266 MIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLRALRKLPRPVRGLSVTYYLEAKM 1325
Query: 1364 WNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGI 1423
S+ + +L+N A+R+RHW++LM+ T V F M + TL ++ ++LH + D + I
Sbjct: 1326 KAFKDSIPLLLDLKNEALRDRHWKELMEKTSVFFEMTETFTLENMFAMELHKHTDVLNEI 1385
Query: 1424 VDKAAKEMGMEKTLKELQTTWAGMEF---QYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQ 1480
V A KE+ +EK +KE+ TW M+F +Y + +L S +++I+ L+DN LQ
Sbjct: 1386 VTAAIKEVAIEKAVKEILDTWENMKFTVVKYCKGTQERGYILGSVDEIIQSLDDNTFNLQ 1445
Query: 1481 NLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDS 1540
++ S++V FL+ V W+K LS + VI IW VQR W +LESIF G DIR+QLP+++
Sbjct: 1446 SISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIGG-DIRSQLPEEA 1504
Query: 1541 KRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLA 1600
K+F+ ID FK + + K P + + P L+++ L C+K+L +YLD+KR A
Sbjct: 1505 KKFDNIDKVFKRIMGETLKDPVIKRCCEAPNRLSDLQNVSEGLEKCQKSLNDYLDSKRNA 1564
Query: 1601 FPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKE 1660
FPRF+F+S +LL IL + + P VQ H+ K++DN+A +RF SGE K M S E
Sbjct: 1565 FPRFFFISDDELLSILGS-SDPLCVQEHMIKMYDNIASLRFNDGDSGE--KLVSAMISAE 1621
Query: 1661 EEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAY-EEKPREQWLFDHPAQVA 1719
E + F + G+VE W+ VL M+ T R E + Y E++ R W+ + V
Sbjct: 1622 GEVMEFRKILRAEGRVEDWMTAVLNEMRRTNRLITKEAIFRYCEDRSRVDWMLLYQGMVV 1681
Query: 1720 LTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTI 1779
L +Q+WWT EV F + ++G + AMK+Y +K Q+ L+T + LSK DR+K T+
Sbjct: 1682 LAASQVWWTWEVEDVFHKAQKGEKQAMKNYGRKMHRQIDELVTRITMPLSKNDRKKYNTV 1741
Query: 1780 CTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGN 1839
IDVHARD+V I + A+ F W SQLR WD E C F Y YEY+G
Sbjct: 1742 LIIDVHARDIVDSFIRGSILEAREFDWESQLRFYWDREPDELNIRQCTGTFGYGYEYMGL 1801
Query: 1840 TPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQ 1899
RLVITPLTDR Y+TLTQ+L + + GAPAGPAGTGKTETTKDL +ALG+L V NC E
Sbjct: 1802 NGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEG 1861
Query: 1900 MDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEE 1959
MDY++ G I+ GLAQ GAWGCFDEFNRI VLSV++ Q+++I++A+ + F F G+E
Sbjct: 1862 MDYRAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTTFQFEGQE 1921
Query: 1960 ISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSL 2019
ISL+ +GIFITMNPGYAGRTELPE++K+LFRP ++VPD + ICEIML +EGF+EA++L
Sbjct: 1922 ISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLEAKTL 1981
Query: 2020 ARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNI 2079
A+K LY+L +E LSKQ HYD+GLRA+KSVLV+AG LKRG D ED VLMR+LRD N+
Sbjct: 1982 AKKMTVLYKLAREQLSKQYHYDFGLRALKSVLVMAGELKRGSSDLREDVVLMRALRDMNL 2041
Query: 2080 PKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEE 2139
PK V +D+P+F+GLI DLFP LD PR R P+F V + + + V KVVQ+ E
Sbjct: 2042 PKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYAVLPIQVDKVVQMFE 2101
Query: 2140 LLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATG 2199
+ RH+ VVG GKS V+ +L + + LNPKAV+ EL+GI++P T
Sbjct: 2102 TMLTRHTTMVVGPTRGGKSVVINTLCQAQTKLGLTTKLYILNPKAVSVIELYGILDPTTR 2161
Query: 2200 EWKDGLFSSIMRELANITHDGP-KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPL 2258
+W DG+ S+I RE+ T K+IL DGD+D +W+E++N+VMDDN++LTLA+ ERI L
Sbjct: 2162 DWTDGVLSNIFREINKPTDKKERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRL 2221
Query: 2259 NPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILF 2318
LLFE+ L+ A+PATVSR G++Y++P +L + P W+ + + E+ NL LF
Sbjct: 2222 QAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLF 2281
Query: 2319 DKYLPTCLDTL---------RTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEI 2369
+KY+P +D + + K I+P + +MV + +L+ LL E D +
Sbjct: 2282 EKYVPYLMDVIVEGIVDGRQAEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----L 2337
Query: 2370 YEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTEFKTV----------KFPSQ-GTIF 2418
E YF+ A + G ++++D + + + L TV + P Q T++
Sbjct: 2338 LECYFLEALYCSLGASLLEDGRMKFDEYIKR--LASLSTVDTEGVWANPGELPGQLPTLY 2395
Query: 2419 DYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVG 2478
D++ D + ++ PWSKLVP++ PE LVHT +T R + +E+++ ++PV+ VG
Sbjct: 2396 DFHFDNKRNQWVPWSKLVPEYIHAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVG 2455
Query: 2479 TAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNK 2538
+GT K+ L +L E +V V F+ TTS +Q LE +EK+ YGPP K
Sbjct: 2456 ESGTSKTATTQNFLKNLSEETNIVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGK 2515
Query: 2539 KLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSK-LSLKEITNVQYVSCMNPTA 2597
+L+ F+DDMNMP VD YGT QP +++ L+ G+ YDR K L+ K I ++ +++ M
Sbjct: 2516 RLLVFMDDMNMPRVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAG 2575
Query: 2598 GSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLAL 2656
G ++PR FSVF + FP ++L IYS IL H F S+ L L
Sbjct: 2576 GGRNEVDPRFISLFSVFNVPFPSEESLHLIYSSILKGH--TSTFHESIVAVSGKLTFCTL 2633
Query: 2657 AFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYR 2716
A ++ I PT KFHYIFNLRD + +F G++ ++ E ++ ++R++ +E RV+
Sbjct: 2634 ALYKNIVQDLPPTPSKFHYIFNLRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFH 2693
Query: 2717 DKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQT-QSPNLYCHFANGI--GEPK-YMPVQ 2772
D+++ E D L +Q + + +D VE + P L+ F + GEP+ Y +Q
Sbjct: 2694 DRLISETDKQL---VQQHIGSLVVEHFKDDVEVVMRDPILFGDFQMALHEGEPRIYEDIQ 2750
Query: 2773 SWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQ 2832
+E E LE +NE NT M+LVLF+DA+ H+ ++RI+ RG+ALLVGVGGSGKQ
Sbjct: 2751 DYEAAKALFQEILEEYNESNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQ 2810
Query: 2833 SLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERF 2892
SL+RLAAF +S +VF+I L +GY F+ DL SL LK G++N +FL TDA VA+E F
Sbjct: 2811 SLSRLAAFTASCEVFEILLSRGYSENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGF 2870
Query: 2893 LVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVT 2952
L LIN++L SG +P L+S++E E+I+S + E QG+ +E+ W++F+++ L +
Sbjct: 2871 LELINNMLTSGIVPALFSEEEKESILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIV 2930
Query: 2953 LCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSIS 3012
L SPVG+ LR R FP +VN T I WF WP QAL +V+ FL I +++
Sbjct: 2931 LGMSPVGDTLRTWCRNFPGMVNNTGIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVV 2990
Query: 3013 KFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENG 3072
K + VH SV+ SQ +L +R NY TPK++L+FI Y LL + + +RL+ G
Sbjct: 2991 KHVVLVHQSVDHYSQQFLQKLRRSNYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGG 3050
Query: 3073 LLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVET------DKVSREKAMAD 3126
L KL + Q+D+L KLA Q++ L +K+ + L++ + V T K++ EKAM
Sbjct: 3051 LDKLKEATIQLDELNQKLAEQKIVLAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEI 3110
Query: 3127 EEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVS 3186
EE+ KV + ++ + E LA+ P L AA+ L L+K+++TE++SF PP V
Sbjct: 3111 EEQNKV------IAMEKAEAETTLAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQ 3164
Query: 3187 NVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQ 3246
V ++++ + K+ +WK AK M+ FL SL+ + ++I ++ +K I+ L+
Sbjct: 3165 TVCECILIM-----KGYKELNWKTAKGVMSD-PNFLRSLMEIDFDSITQSQVKNIKGLLK 3218
Query: 3247 DPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAI 3306
E + S A G+ +V ++ + +VF +++PKR+ + + + + +L I
Sbjct: 3219 TLNTTTEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFYLTKRELERI 3278
Query: 3307 KAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAV 3366
+ ++A + + L L A++E A +K K Q+EAE+ + A++L+ GL SEN+RW + +
Sbjct: 3279 QNELAAIQKELETLGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENIRWLNDL 3338
Query: 3367 QNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPL 3426
+ L GD LL AF+SY G FT ++R +++R W+ + L+ IP++
Sbjct: 3339 DELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNRIWQNDI--LEREIPLSQPFRLE 3396
Query: 3427 RMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGE-DLR 3485
+L DD +++ W ++GLP D +SV+N + R+PL +DPQ Q + WIK K + +LR
Sbjct: 3397 SLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLR 3456
Query: 3486 VTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREV-IKKGR-FIKIGDKEC 3543
V +L+ +E +++ G L +++E IDPV+ +L + + + +GR FI +GDKE
Sbjct: 3457 VASFNDPDFLKQLEMSIKYGTPFLFRDVDEYIDPVIDNVLEKNIKVSQGRQFIILGDKEV 3516
Query: 3544 EYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKS 3603
+Y+ FRL L+TKLANP Y P + +A +IN+TVT GLEDQLL+ +V+ ER +LE+ +
Sbjct: 3517 DYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQRE 3576
Query: 3604 DLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKV 3663
L ++ + K LK LEDSLL L++++GN L LV LE TK A EV +K++ A+
Sbjct: 3577 HLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVDLVHTLEETKSKATEVSEKLKLAEK 3636
Query: 3664 TEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESL 3723
T + I+ R+ YRPAA R ++L+F++++++ ++ MYQ+SL AF VF+ +++++ PD L
Sbjct: 3637 TALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFRLSLKKSLPDSIL 3696
Query: 3724 RERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPV- 3782
+R+ N++D++TFS+Y + GLFE KL + +T +I V ELDF L+ +
Sbjct: 3697 MKRLRNIMDTLTFSIYNHGCTGLFERHKLLFSFNMTIKIEQAEGRVPQEELDFFLKGNIS 3756
Query: 3783 --QTGTASPVEFLSHQAWGAVKVLSSM--EEFSNLDRDIEGSAKSWKKFVESECPEKEKL 3838
++ P +LS Q W + +LS M + F L D+E + W+++ + + E+ +
Sbjct: 3757 LEKSKRKKPCAWLSDQGWEDIILLSEMFSDNFGQLPDDVENNQTVWQEWYDLDSLEQFPV 3816
Query: 3839 PQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPAT 3897
P + N T Q+L +LR R DR+ A+ D+V +G KYV + F FE+S P +
Sbjct: 3817 PLGYDNNITPFQKLLILRCFRVDRVYRAVTDYVTVTMGEKYVQPPMISFEAIFEQSTPHS 3876
Query: 3898 PMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVI 3957
P+ FILSPG DP D+ + G+ N F +++GQGQE VA L+ A +G W++
Sbjct: 3877 PIVFILSPGSDPATDLMKLAERSGFGGNRLKF--LAMGQGQEKVALQLLETAVARGQWLM 3934
Query: 3958 LQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNE 4017
LQN HL+ KWL LEK LE ++ HP+FR++++ +P P GIL+ S+K+ E
Sbjct: 3935 LQNCHLLVKWLKDLEKSLERITK-PHPDFRLWLTTDPTKG-----FPIGILQKSLKVVTE 3988
Query: 4018 PPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYP 4077
PP G+ N+ + + L+ C FK +++ L +FHAVV ERRKFG GWN Y
Sbjct: 3989 PPNGLKLNMRATYFKISHEMLDQCPHPA-FKPLVYVLAFFHAVVQERRKFGKIGWNVYYD 4047
Query: 4078 FNTGDLTISVNVLYNFL-----EANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLG 4132
FN D + + +L +L + + ++P+ L+YL GE+MYGG D +DRR+ Y+
Sbjct: 4048 FNESDFQVCMEILNTYLTKAFQQRDPRIPWGSLKYLIGEVMYGGRAIDSFDRRILTIYMD 4107
Query: 4133 EFIRPEMLEGELSLAP---------GFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNA 4183
E++ + + + P + +P + + + I+A +P ++GLHPNA
Sbjct: 4108 EYLGDFIFD---TFQPFHFFRNKEVDYKIPVGDEKEKFVEAIEALPLANTPEVFGLHPNA 4164
Query: 4184 EIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMA 4243
EIG+ TQ + ++ +LELQP+ ++ +G +R++ + + +EI ++ F++ ++
Sbjct: 4165 EIGYYTQAARDMWAHLLELQPQTGES--SSGISRDDYIGQVAKEIENKMPKVFDLDQVRK 4222
Query: 4244 KV-EERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMV 4302
++ +P VV QE R N L + +SL EL+ L GE+ M++ ++++ +L+ +
Sbjct: 4223 RLGTGLSPTSVVLLQELERFNKLVVRMTKSLAELQRALAGEVGMSNELDDVARSLFIGHI 4282
Query: 4303 PESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQS 4362
P W R A + L W L R + W + + PS +WL+G P+S+LTA++Q+
Sbjct: 4283 PNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWVTE-SEPSVMWLSGLHIPESYLTALVQA 4341
Query: 4363 TARKNEWPLDQMALQCDMTK-KNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLK 4421
T RKN WPLD+ L +TK ++ +E +G ++ GL++EGA WD + G + ++K K
Sbjct: 4342 TCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGADWDIEKGCLIKSKPK 4401
Query: 4422 DLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR----GPTYVWTFNLKTKENPSKWVL 4477
L +P++ I I A + ++ + PVY TS R G V+ +L T + S WVL
Sbjct: 4402 VLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTSMRRNAMGVGLVFEADLFTTRHISHWVL 4461
Query: 4478 AGVALLL 4484
GV L L
Sbjct: 4462 QGVCLTL 4468
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2205 bits (5714), Expect = 0.0
Identities = 1347/4092 (32%), Positives = 2164/4092 (52%), Gaps = 150/4092 (3%)
Query: 467 FSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRL 526
F G +G +++ + ++ + F + L L +++T + D ++F ++DL+
Sbjct: 412 FFGAQGPQITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMT 471
Query: 527 GTIFIQAFDDAPGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYS 586
+ AF+ + H LLD L R + R K + L +FN +L V
Sbjct: 472 QNLITSAFELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVN---- 527
Query: 587 QHVQEEAELGFSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQ 646
E + + + +G RW LR+RI + H GK
Sbjct: 528 ----RERNKKWPDLEPYVAQYSGKARWVHILRRRIDRVMTCLAG-AHFLPRIGTGKESVH 582
Query: 647 KYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKE-ITINFNPQLISVLK 705
Y+ M+ +++ + +++W ++ + L PLL+ E + +NF+ L+ +
Sbjct: 583 TYQQMVQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFA 642
Query: 706 EMSYLEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEEL 765
E+ Y E R + P + + R L NL L+A YN+++ L E L +E +
Sbjct: 643 EIDYWE-RLLFETPHYVVNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERI 701
Query: 766 QNIDLRLRAAEETLNWKTEGICDY-VTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTP 824
+ +D ++ + L+W +G + +TE ++ + + K + I +
Sbjct: 702 RLLDKKIHPGLKKLHWALKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEK 761
Query: 825 IFKTKDGKRESLLSLDDRHDRMEKYYNLIKESGLKIH----ALVQENLGLFSAD--PTSN 878
+ GKR L+ D+ E + +++ + +H ++ + +F D
Sbjct: 762 LLVRISGKRV-YRDLEFEEDQRE-HRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQ 819
Query: 879 IWKTYVNSIDNLLLNGFFLAIECSLKYLLE--NTECKAGLTPIFEAQLSL------AIPE 930
W Y+ +D ++ + L ++ SL L + N + K P+F+ + L ++ +
Sbjct: 820 QWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQ 879
Query: 931 LVFYPSLES--GVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQVDLDGIPDLANM 988
+ F P+L++ GV + + I+ +P ++ + V+ D D+ +
Sbjct: 880 VEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQD--EDIKKI 937
Query: 989 RRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGI 1048
+ + + L Y T+ Y ++ ++ + ++
Sbjct: 938 QTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQRL----------------- 980
Query: 1049 PENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFK 1108
NPP+ S F I Y + V + E + ++ +D K SL+ W F
Sbjct: 981 --NPPV-SSFVADIARYTEVANNVQKEETVTNIQ-FVLLDCSHLKFSLVQHCNEWQNKFA 1036
Query: 1109 QHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEP 1168
L + L L ++K++ + + + + G+ + + A+K +N + P
Sbjct: 1037 TLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVS--LQLVDALKHDLANVETQIPP 1094
Query: 1169 LKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCT 1228
+ + +L+ YE + ++V + L+ L +W ++ + KQ + + T L
Sbjct: 1095 IHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSAD 1154
Query: 1229 AFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHIE--IQQMESTMASISESASLFEVNV 1286
F + E F + F + + + + + M S+ + +F++
Sbjct: 1155 DFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQ 1214
Query: 1287 PDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNL 1346
P K L+ KE+ L+++W+ + + W+T + + E ME R + L
Sbjct: 1215 PPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKL 1274
Query: 1347 DKEV--RAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDT- 1403
KE R W+ S + ++ +++L+NPA+RERHW Q+ F + ++
Sbjct: 1275 AKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESF 1334
Query: 1404 TLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLC 1463
TL +++L + + +++ I A KE+ +E L+ + TW + P+ L
Sbjct: 1335 TLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLR 1394
Query: 1464 SDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLE 1523
E++ + LEDNQV L + S++V F ++V W++ LS + VI + VQR W +LE
Sbjct: 1395 GTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLE 1454
Query: 1524 SIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRL 1583
+IF G EDIR QLP +S F+ ++ ++K + K N +++T+ PGL + L ++ L
Sbjct: 1455 NIFLG-EDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTIL 1513
Query: 1584 CLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQL 1643
+K+L YL+TKR FPRFYFLS+ DLL+IL P+ VQ HL K FDN+ +R Q
Sbjct: 1514 EDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQK 1573
Query: 1644 DASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYE 1703
++GM+S + EY+ F G VE WL V M+ T+R + A
Sbjct: 1574 VGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALR 1633
Query: 1704 E--KPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKK-QVAQLKTL 1760
+ R++W+ + QV +T +QI WT +V +E + + KK QV+ L
Sbjct: 1634 KFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKY 1693
Query: 1761 ITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKH 1820
+ G L+K R KI+ + TI++HARDV+ K+ + + +F WLSQLR W+ ++
Sbjct: 1694 SEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDD 1753
Query: 1821 CFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETT 1880
C + QF Y+YEYLGN+ RLVITPLTDRCY+TLT +LHL G+P GPAGTGKTET
Sbjct: 1754 CVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETV 1813
Query: 1881 KDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVK 1940
KDLG+ALGI V V NCSE +DYKS G +Y GLAQTGAWGCFDEFNRI++EVLSVVA Q+
Sbjct: 1814 KDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQIL 1873
Query: 1941 SIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDF 2000
I A+ F F G EI+L S GIFITMNPGYAGRTELPENLKS+FRP AMVVPD
Sbjct: 1874 CILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDS 1933
Query: 2001 ELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRG 2060
LI EI+L EGF + LA+K TLY L + LS+QDHYD+GLRA+ S+L AG +R
Sbjct: 1934 TLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRL 1993
Query: 2061 DPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIV 2120
PD +++VL+ S+RD NI K+ + D P+F ++ DLFP +++P V + I
Sbjct: 1994 QPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIR 2053
Query: 2121 DLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGK-----------SQVLRSLHKTYQ 2169
D+ LQ+ + KV QL E RHS +VG G+GK S + R+ +
Sbjct: 2054 DMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFN 2113
Query: 2170 IMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGD 2229
I++ P LNPKA++ EL+G + +T EW DG+ SS+MR KWIL DG
Sbjct: 2114 IVREFP----LNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGP 2169
Query: 2230 IDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINP 2289
+D +WIE++N+VMDDNKVLTL + ERI + + LLFE+ L A+PATVSR G++Y +
Sbjct: 2170 VDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDY 2229
Query: 2290 ADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVC 2349
ADLGW P V SW+EKR + E L +F+K + L + K+++P+PE S + +C
Sbjct: 2230 ADLGWKPYVQSWLEKRP-KAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLC 2288
Query: 2350 HLLECLLTTED--IPADCPKEI--YEHYFVFAAIWAFGGAMVQD---QLVDYRAEFSKWW 2402
L L T E+ PAD + E FVF+ IW+ ++ ++ ++ Y E
Sbjct: 2289 KLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEG-- 2346
Query: 2403 LTEFKTVKFPSQGTIFDYYIDPETKKFEPW-SKLVPQFEFDPEMPLQACLVHTSETIRVC 2461
FP++ T+++Y++DP+ + + + KL + + P P +V T +T+R
Sbjct: 2347 -------SFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYN 2399
Query: 2462 YFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLE 2521
Y + L+A Q P++LVG GTGK+ + + L SL + V V + TTS +Q+++E
Sbjct: 2400 YLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIE 2459
Query: 2522 KPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSL 2581
+EK+ Y P G K +I F+DD+NMP D +G+ P +IR +DYG WYDR+K ++
Sbjct: 2460 SRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTI 2519
Query: 2582 KEITNVQYVSCMNPTAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF 2640
K I + ++ M P G T I+PRL+ F++ ++FP + I+ ++ Q KL +F
Sbjct: 2520 KYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQ--KLQDF 2577
Query: 2641 PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST 2700
++ + + L + + FLPT K HY+FNLRD + +FQG+L ++ + +
Sbjct: 2578 EEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTK 2637
Query: 2701 WDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFA 2760
+ RL++HE RV+ D++V+ D + F I ++ L FD + ++ P ++ F
Sbjct: 2638 SSITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDF- 2696
Query: 2761 NGIGEPK-YMPVQSWELLTQTLVEALENHNEVNTV--MDLVLFEDAMRHVCHINRILESP 2817
+ EPK Y + +L + AL +N +V M LVLF +A+ H+ I R++ P
Sbjct: 2697 --LKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQP 2754
Query: 2818 RGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLN 2877
RGN LLVG+GGSG+QSL RLA+ I FQI + K Y+ Q+F+ D+ L +AGV+
Sbjct: 2755 RGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKT 2814
Query: 2878 TVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENC 2937
T F+ D Q+ADE FL IN++L+SGE+P+LY DE E I S++ ++ + + + ++ ++
Sbjct: 2815 TSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSL 2874
Query: 2938 WKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFL 2997
+ + I+R++ L + LC SP+G+ R R++PA+VNCT I+WF EWPQ+AL V+ + L
Sbjct: 2875 FAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCL 2934
Query: 2998 QNTE-GIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLH 3056
+ G + + + +++ +H SV Q SQ L +R+NY TP +LE + Y+ LL
Sbjct: 2935 IGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLG 2994
Query: 3057 RHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETD 3116
R+EL + +L GL K+ T +V + +L + ++ + + ++ + ++ +
Sbjct: 2995 EKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKR 3054
Query: 3117 KVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELK 3176
+ ++ +K+AV ++ + + ++DL +A PAL A AL +LNK ++ E+K
Sbjct: 3055 EADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIK 3114
Query: 3177 SFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHEN 3236
S+G PP V V AVM+L RG P +W AK + + F+ SLINF+K+NI +
Sbjct: 3115 SYGRPPAQVEIVMQAVMIL---RGNEP---TWAEAKRQLGE-QNFIKSLINFDKDNISDK 3167
Query: 3237 CLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADL 3296
LK I Y P+F P+ + S AA LC WV + + ++ VEPKR +N A A L
Sbjct: 3168 VLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQL 3227
Query: 3297 TAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLA 3356
Q LA + K+ + E L L ++++ A K + ++++E + + A LV GLA
Sbjct: 3228 REKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLA 3287
Query: 3357 SENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTP 3416
E RW + VQ ++ L GD LL AF+SY+G F YR ++++ W + +L+ P
Sbjct: 3288 GEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVP 3347
Query: 3417 IPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWI 3476
+ A+D L + V W +GLP+D S EN I+ RW LM+DPQ Q +KWI
Sbjct: 3348 CSPSFAID--NFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWI 3405
Query: 3477 KN-KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG-- 3533
KN + G+ L++ + YL+I+E A+ G VL++N++E +DP L P+L + V + G
Sbjct: 3406 KNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGR 3465
Query: 3534 RFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSM 3593
++IGDKE EYN FR + TKL+NPHY PE A+ T++NF V GLE QLL VV
Sbjct: 3466 LLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRK 3525
Query: 3594 ERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAE 3653
ERP+LE+ K L K LK LED +L L+ A+G+ L + LV L +K TA E
Sbjct: 3526 ERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATE 3585
Query: 3654 VEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKA 3713
V ++++ ++ TE+ + ARE YRP A RAS+L+F++ND+ I PMYQFSL A+ +F +
Sbjct: 3586 VTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILS 3645
Query: 3714 VERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVE 3773
++++ L +R+ L D T++VY+YT R LFE KL + + +IL + ++N E
Sbjct: 3646 IDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDE 3705
Query: 3774 LDFLLRSPVQTGTASPVE-----FLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFV 3828
+F LR V ++ +L+ W + L + F L E + W +
Sbjct: 3706 YNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWY 3765
Query: 3829 ESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFA 3887
+ PEK LP EW+N +QR+ ++R++R DR+ + + F+ LGS+++ L+
Sbjct: 3766 TNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMK 3825
Query: 3888 TSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALD 3947
+ E+S P +P+ FILSPGVDP + +G Q FH +SLGQGQ +A L
Sbjct: 3826 SVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMA---QRFHALSLGQGQAPIAARLLR 3882
Query: 3948 LAAKKGHWVILQNIHLVAKWLSTLEKKLEE-HSENSHPEFRVFMSAEPAPSPEGHIIPQG 4006
+GHWV L N HL W+ L+K +E+ E+ HP FR+++S+ P P P
Sbjct: 3883 EGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPD-----FPIS 3937
Query: 4007 ILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRK 4066
IL+ SIK+T EPP G+ AN+ + ++ CS+ ++K +LF+LC+FH+V+ ER+K
Sbjct: 3938 ILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKK 3997
Query: 4067 FGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRL 4126
F GWN Y FN D +S N+L +L+ + P+D L+YL I YGGH+TDDWDRRL
Sbjct: 3998 FLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRL 4057
Query: 4127 CRTYLGEFIRPEMLE---GELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNA 4183
TY+ ++ + L LS + +P + Y +YI + P +G HPNA
Sbjct: 4058 LTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNA 4117
Query: 4184 EIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERV---TDEFNIPE 4240
++ ++ LF T+L LQP+ + R G G TREEKV L ++ +++ D +
Sbjct: 4118 DVASQITEAQTLFDTLLSLQPQITPTRAG-GQTREEKVLELAADVKQKIPEMIDYEGTQK 4176
Query: 4241 LMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFD 4300
L+A + +P VV QE R N L + I SL +LE G++G + M++ +E + N ++
Sbjct: 4177 LLAL--DPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDA 4234
Query: 4301 MVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIM 4360
VP W +AYPS LAAW DL R+++ E W P WL+GF P FLTA++
Sbjct: 4235 HVPPLWG-KAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVL 4293
Query: 4361 QSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKL 4420
QS+AR+N +D ++ + ++ + PP++G ++ GL++EGA WD + + EA+
Sbjct: 4294 QSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEP 4353
Query: 4421 KDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRG-----PTYVWTFNLKT-KENPSK 4474
L MP + + + K+ + +YSCP Y R ++V +L++ P
Sbjct: 4354 MQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDH 4413
Query: 4475 WVLAGVALLLQI 4486
W+ G ALL+ +
Sbjct: 4414 WIKRGTALLMSL 4425
Score = 96.7 bits (239), Expect = 5e-19
Identities = 75/289 (25%), Positives = 134/289 (46%), Gaps = 19/289 (6%)
Query: 80 GLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGDLPAAPLEHLAALFSE 139
GL + G+ V ++ L ++F+R P P ++F V G + + L L
Sbjct: 123 GLKLELGMPVQTQNQL-----VYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGG 177
Query: 140 VVLP-VLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFA 198
V P + AN WP I H H L+ +++G T+L +PA + M
Sbjct: 178 VFAPQIFANT----GWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNM--- 230
Query: 199 DSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSR 258
K E V+ DK ++ +E+++I W+ Q++ +L + + + GEN P E+EFW++R
Sbjct: 231 --KPEMVIK--DKELVQRLETSMIHWTRQIKEMLSAQET--VETGENLGPLEEIEFWRNR 284
Query: 259 YEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQR 318
DL I QL V+ + +L +SSY F + + + +AQ L L+
Sbjct: 285 CMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKE 344
Query: 319 HLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICN 367
+ L + ++ +L L+ ++ +IW Y + RLT L +++C+
Sbjct: 345 PYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKVCD 393
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 2048 bits (5307), Expect = 0.0
Identities = 1237/3728 (33%), Positives = 1971/3728 (52%), Gaps = 217/3728 (5%)
Query: 906 LLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVP- 964
++E E L P+F +L L + L+F PSLE + G V ++ +P+LVP
Sbjct: 499 MVEKQEEDESLIPMFLTELMLTVQSLLFEPSLEDFLDG-ILGAVNHCQNTVLSVPNLVPD 557
Query: 965 RLSPQNGSPHYQVDLDGI-----PDLA----------NMRRTLMERVQRMMGLCCGYQST 1009
SP+ L+G P LA + + E +Q Y +T
Sbjct: 558 SYFDAFTSPYINNKLEGKTCGTGPSLAAVFEDDKNFHTIISQIKETIQAAFESARIYAAT 617
Query: 1010 FSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLY 1069
F ++ + E+ L L P ++ F Q++ Y +
Sbjct: 618 FEKFQIFFKENESLDLQALKL--------------------QEPDINFFSEQLEKYHKQH 657
Query: 1070 EEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKS 1129
++ L P + G + ID R + L+ R + L S +DA I ++
Sbjct: 658 KDAVALRPTRNV-GLLLIDTRLLREKLIPSPLRCLEVLNFMLP---RQSKKKVDAIIFEA 713
Query: 1130 ESGLLK-KVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVF 1188
+ K + V + L ++ER + ++ + Q +L++ Y+ P F
Sbjct: 714 QDAEYKLEFVPTTTTEYVHSLLFLDEIQERIESLEDEGNIVTQMYKLMEQYQVPTPPEDF 773
Query: 1189 KQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFR 1248
+ K + V+ + + + ++Q C ++ ++ + ++ +
Sbjct: 774 AVFATM-------KPSIVAVRNAIDKSVGDRESSIKQFCVHLGSDLEELNNEVNE---VK 823
Query: 1249 FDSIHPHQMLDAR------HIEIQQMESTMASISESA-------SLFEVNVPDYKQLRQC 1295
+ P Q+LD + + ++S +A + + A F+V V ++ L +
Sbjct: 824 LQAQDP-QILDISADQDKIRLILNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEV 882
Query: 1296 RKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDA 1355
E+ + LWD+ W + + ++ E + + ++A+ + L+K +
Sbjct: 883 SAELKLKQLLWDSFSEWDKLQQEWLKSKFDCLDPEVLNGQVSKYAKFVTQLEKGLPPNSV 942
Query: 1356 FTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFT-MDQDTTLAHLLQLQLH 1414
L+ V L + +L+NP ++ RHW + Q + + TL L QL +
Sbjct: 943 VPQLKYKVEKMKEKLPVIIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVF 1002
Query: 1415 HYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRT-NVPLLCSDEDLIEVLE 1473
+ E++ I +A+ E +E LK+++ +W EF PH + +V +L +D+ +L+
Sbjct: 1003 DFGQEIQDISGQASGEAALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLD 1062
Query: 1474 DNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIR 1533
D+ + + L S+Y+ V WQK+L+ + + W QR W +LESIF + DI+
Sbjct: 1063 DSTINVATLASSRYLGPLKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFN-APDIQ 1121
Query: 1534 AQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEY 1593
QLP ++K F +D +KE+ ++PN ++ +PGL E ++ L +K L Y
Sbjct: 1122 RQLPAEAKMFLQVDKSWKEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAY 1181
Query: 1594 LDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQL---------D 1644
L++KR+ FPRFYFLS+ +LL+IL+ PQ VQ HL K FD+++K+ F L
Sbjct: 1182 LESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPG 1241
Query: 1645 ASGEPTKTS----LGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVT 1700
GEP K L M S E E V+ + G VE WL V M ++R +
Sbjct: 1242 IDGEPEKVYTNDILAMLSPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIA 1301
Query: 1701 AYEEKPREQWLF-DHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKT 1759
Y+ K R W+ HP+QV LT +QI W ++ + A+K++ K +L
Sbjct: 1302 DYQGKLRTDWVVAGHPSQVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNA 1361
Query: 1760 LITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVK 1819
L ++ G L K R + + TIDVHARD+V +++ KV+ ++F W QLR+ WD ++
Sbjct: 1362 LAAIVQGSLPKLHRNILTALITIDVHARDIVTELVQSKVETVESFDWQRQLRYYWDIDLD 1421
Query: 1820 HCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTET 1879
+C A + +Q+ Y YEYLG PRLVITPLTDRCY+ L +L L + GAPAGPAGTGKTET
Sbjct: 1422 NCVARMALSQYTYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTET 1481
Query: 1880 TKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQV 1939
TKDL +AL I VFNCS+ +DYK G + GLAQ+GAW CFDEFNRI +EVLSV+A Q+
Sbjct: 1482 TKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQL 1541
Query: 1940 KSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPD 1999
+I++A K F F G EI L + FITMNPGYAGRTELP+NLK+LFRP AM+VP+
Sbjct: 1542 ITIRNAKAAKLSRFMFEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPN 1601
Query: 2000 FELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKR 2059
+ LI E++L +EGF ++ LARK +Y+LC E LS+QDHYD+G+RA+KSVLV+AGSLKR
Sbjct: 1602 YALIAEVILYSEGFESSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKR 1661
Query: 2060 GDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAI 2119
+PD ED VL+R+L+D N+PK +TDD +F G+I DLFP + +P ++ + +
Sbjct: 1662 ENPDLNEDVVLIRALQDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVM 1721
Query: 2120 VDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTD 2179
LQ E V KV+Q E + VRH V +VG G GK+ V R L +T +++ +
Sbjct: 1722 NRQNLQPEMCMVRKVIQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENS 1781
Query: 2180 ---------LNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKWILLDGDI 2230
LNPK++T EL+G +N T EWKDGL + +R N T + KWI+ DG +
Sbjct: 1782 FYQAVKTYVLNPKSITMGELYGEVNNLTLEWKDGLMALSVRAAVNDTSEDHKWIISDGPV 1841
Query: 2231 DPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPA 2290
D +WIE++NTV+DDNK+L LA++ERI L P + +LFE+ LR A+PATVSR G+++++P
Sbjct: 1842 DALWIENMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPE 1901
Query: 2291 DLGWNPPVSSW---IEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQM 2347
+L W P V +W I K+ + + + LF +Y+ L + + + IP + S V
Sbjct: 1902 ELKWMPYVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTT 1961
Query: 2348 VCHLLECLLTTED-----IPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFSKWW 2402
+C LLE L+ +D + I FVF +W+ GG + + +Y F +
Sbjct: 1962 LCCLLESLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTE----NYYDSFDTFI 2017
Query: 2403 LTEF---KTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIR 2459
T+F + P+ G ++ ++D +TK+ +PW +++P F+++ ++P LV T++T+R
Sbjct: 2018 RTQFDDNPDARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVR 2077
Query: 2460 VCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEA-YLVKNVPFNYYTTSAMLQA 2518
Y ME+L+A + V+ G G GKSV+ L + A Y+ + F+ T+SA Q
Sbjct: 2078 YGYLMEKLLAVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQE 2137
Query: 2519 VLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSK 2578
++E LE+K G PGNK+++ F+DD+NMP +D YG+ P ++RQ+ D+G +YDR+K
Sbjct: 2138 IIESKLERKRKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNK 2197
Query: 2579 LSLKEITNVQYVS-CMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKL 2637
L KEI +V +S C P G + PR RHFS+ L P +L I+ IL L
Sbjct: 2198 LFWKEIQDVTIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGF--L 2255
Query: 2638 GNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECV 2697
+FP +++++ +++ ++ + K++ LPT K HY+FNLRD + QGIL +
Sbjct: 2256 SDFPPAVKQTASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTI 2315
Query: 2698 KSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYC 2757
+ + RL+ HE RV+ D+++ +D F I TE+ K F D P ++
Sbjct: 2316 REEIQIFRLFCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFG 2375
Query: 2758 HFANGIGEPK----YMPVQSWELLTQTLVEALENHNEVN-TVMDLVLFEDAMRHVCHINR 2812
F G K Y + E L + L+++N N + LV F+DA+ HV I R
Sbjct: 2376 DFIK-FGADKADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIAR 2434
Query: 2813 ILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAG 2872
++ RGNALLVGVGG+GKQSLTRLAA I QI L +GY F DL L AG
Sbjct: 2435 MIRQERGNALLVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAG 2494
Query: 2873 VKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVD 2932
V++ N VFL TD Q+ E FL IN++L SGE+P+L+ DE+E +++ R K G+ +
Sbjct: 2495 VEDKNMVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISE 2554
Query: 2933 -NRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALES 2991
NR+ +++FI ++R++L + LC SPVG R R R FP++VNC I WF +WP++AL S
Sbjct: 2555 GNRDEVFQYFISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLS 2614
Query: 2992 VSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLY 3051
VS F + +K+ + VH SV+ ++ Y + +R YTTP S+LE I LY
Sbjct: 2615 VSKTFFSQVDAGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLY 2674
Query: 3052 QSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVV 3111
S+L RK++ +R++NGL KL T+ VD +K L+A E L K+ED + L++ +
Sbjct: 2675 LSMLSEKRKQIISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKL 2734
Query: 3112 GVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTN 3171
V+ + + + E+E V E + D + DL +A PAL AA AL++L+K +
Sbjct: 2735 AVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAANKALDSLDKAD 2794
Query: 3172 LTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKE 3231
++E++ F PP V V A+ +L+ + W +AK + FL L+ ++KE
Sbjct: 2795 ISEIRVFTKPPDLVMTVMEAISILLNAK------PDWPSAKQLLGD-SNFLKRLLEYDKE 2847
Query: 3232 NIHENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNK 3291
NI L ++ Y+ +P+F PE V S A +C WV + + V VEPKRQ L
Sbjct: 2848 NIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRA 2907
Query: 3292 ATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRL 3351
A A+L L +A + + + + L ++K +K + +T + A +L
Sbjct: 2908 AQAELDITMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKL 2967
Query: 3352 VGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLS 3411
L E VRW +++Q F+++ + G++ + A ++Y G FT +YRQSL++ W
Sbjct: 2968 TAALEDEQVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIE-CWIQDCQ 3026
Query: 3412 QLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQ 3471
L+ IP+ P+ + +L D ++ W +GLP D +S EN ++ RWPLM+DPQ Q
Sbjct: 3027 SLE--IPIDPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQ 3084
Query: 3472 GIKWIKNKYGED-LRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREV- 3529
+WI+NK + L++ ++ +L+I+E ++ G VL+E L+E++DP L P+L +++
Sbjct: 3085 ANRWIRNKESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIF 3144
Query: 3530 IKKGR-FIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLA 3588
I GR I++GD + +Y+ FR + TK+ NPHY PE+ + T+INFTVT+ GLEDQLL+
Sbjct: 3145 ISGGRLLIRLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLS 3204
Query: 3589 AVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITK 3648
VV +E+P LE+ + L + N K LKT+E+ +L L ++ GN L L++ L+ +K
Sbjct: 3205 DVVRLEKPRLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSK 3264
Query: 3649 QTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSI 3708
T+ ++ +++EA+ TE IN ARE YRP A + S++YF++ LS+I PMYQ+SLK F
Sbjct: 3265 ITSGAIKTRLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQ 3324
Query: 3709 VFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNRE 3768
+F +E + E+L++R+ L++ + Y RGLFE KL Y L +++
Sbjct: 3325 LFNTTIETSVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGT 3384
Query: 3769 VNAVELDFLLRSPVQTGTASP----VEFLSHQAWGAVKVL-SSMEEFSNLDRDIEG---- 3819
++ E +F LR P +L W A L S F L ++I
Sbjct: 3385 LSDAEWNFFLRGSAGLEKERPPKPEAPWLPTATWFACCDLEESFPVFHGLTQNILSHPIS 3444
Query: 3820 ----------SAKSWKKFVESE------CPEKEKLPQE-WK-NKTALQRLCMLRAMRPDR 3861
+ + W+ + + + EKE Q+ W ++ +L +++ + ++
Sbjct: 3445 IRLGSFETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEK 3504
Query: 3862 MTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLG 3921
+ +AL DFV E LG +++ +D T +++ TP+ FILS G DP+ + R+ G
Sbjct: 3505 VVFALTDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESG 3564
Query: 3922 YTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSEN 3981
Y ++ ++SLGQGQ +AE + A K G+WV LQN HL W+ +E+ ++ ++
Sbjct: 3565 Y---SERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDP 3621
Query: 3982 S---HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTL 4038
FR+F+S+ P+ + P +L+NS+K+TNEPP G+ AN+ +A T
Sbjct: 3622 DSAIKDTFRLFLSSMPS-----NTFPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFF 3676
Query: 4039 EMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANA 4098
E +++ I+F +C+FHA++ ER+KFGP GWN Y FN D ++ L + +
Sbjct: 3677 EENILGKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECALLNLKLYCK-EG 3735
Query: 4099 KVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPG--FPLPGNM 4156
K+P+D L Y+ GEI YGG +TD WD+R RT L F PE LE + + + P
Sbjct: 3736 KIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFAPMAD 3795
Query: 4157 DYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGAT 4216
+ YI+ + P ++G+H NA + F + + L T+LE+QPR S G G +
Sbjct: 3796 SLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTG--GEGKS 3853
Query: 4217 REEKVKALLEEILERVTDEFN---------IPELMAKVEERTPYIVVAFQECGRMNILTR 4267
+E V+ L+ + RV ++ + +L ++ T V QE R N L +
Sbjct: 3854 NDEIVQELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLT---TVLGQEVDRFNNLLK 3910
Query: 4268 EIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNR 4327
I SL L + G + M+ ME + N+ + VP W+ AYPS L +W DL+ R
Sbjct: 3911 LIHTSLETLNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILR 3970
Query: 4328 IKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREE 4387
++ W P + W++GFF PQ FLT +Q+ ARK P+D+++ + + R++
Sbjct: 3971 TSFVDLWL-KRGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQ 4029
Query: 4388 FR--------------------SPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPM 4427
P +G +HG+FM+ + WD + +I +A + P +
Sbjct: 4030 AAVIEAAKTVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVL 4089
Query: 4428 PVMFIKAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTKENPSKWVLA 4478
PV+ + + + ++Y CP+YKT R T +V T L +K + W+
Sbjct: 4090 PVVHFEP-QQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAK 4148
Query: 4479 GVALLLQI 4486
G ALL Q+
Sbjct: 4149 GSALLCQL 4156
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 2020 bits (5234), Expect = 0.0
Identities = 1180/3314 (35%), Positives = 1837/3314 (55%), Gaps = 166/3314 (5%)
Query: 1281 LFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFA 1340
+F + + +Y +L + KE +LW T +W P I+ E +E +
Sbjct: 1002 IFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSESWMNDPLSAIDAEQLEKNVVEAF 1061
Query: 1341 RHIRNLDKEVRAWDAFTGLESTVWNTLSSLRA----VAELQNPAIRERHWRQLMQATGVS 1396
+ + K+ + A + + + + + L+NP +R RHW L ++
Sbjct: 1062 KTMHKCVKQFKDMPACQEVALDIRARIEEFKPYIPLIQGLRNPGMRIRHWETLSNQININ 1121
Query: 1397 FTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPR 1456
+ T A L++ L + + + + + A KE +E+ L +++ W+ + F P+
Sbjct: 1122 VRPKANLTFARCLEMNLQDHIESISKVAEVAGKEYAIEQALDKMEKEWSTILFNVLPYKA 1181
Query: 1457 TNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQ 1516
T+ +L S ++ ++L+D+ V QN+ S Y F + ++ W+ KL V+ W Q
Sbjct: 1182 TDTYILKSPDEASQLLDDHIVMTQNMSFSPYKKPFEQRINSWENKLKLTQEVLEEWLNCQ 1241
Query: 1517 RTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKL 1576
R+W +LE IF+ SEDI QLP +SKR++ ++ +K++ +A + V+ + + + L
Sbjct: 1242 RSWLYLEPIFS-SEDINQQLPVESKRYQTMERIWKKIMKNAYENREVINVCSDLRMLDSL 1300
Query: 1577 EDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNM 1636
D L L +K L+EYL+TKR AFPRFYFLS +LL+ILS P VQ HL K F+N+
Sbjct: 1301 RDCNKILDLVQKGLSEYLETKRSAFPRFYFLSDDELLEILSQTKDPTAVQPHLRKCFENI 1360
Query: 1637 AKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMT 1696
A++ FQ D MYS E E V S VE WL V MKA+V +
Sbjct: 1361 ARLLFQEDLE------ITHMYSAEGEEVQLCFSIYPSSNVEDWLREVERSMKASVHDIIE 1414
Query: 1697 EGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQ 1756
+ + AY PR QW+ + P QV + Q +WT EV A LE G + + + Q
Sbjct: 1415 KAIRAYPTMPRTQWVLNWPGQVTIAGCQTYWTMEVAEA---LEAG--NLRSQLFPQLCQQ 1469
Query: 1757 LKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDD 1816
L L+ ++ G+LS+ R + + I+VHA+DVV+K+I + V + F W+SQLR+ W +
Sbjct: 1470 LSDLVALVRGKLSRMQRAVLSALIVIEVHAKDVVSKLIQENVVSVNDFQWISQLRYYWTN 1529
Query: 1817 EVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGK 1876
+ +A+F+Y YEYLGN+ RLVITPLTDRCY+TLT +LHL GAPAGPAGTGK
Sbjct: 1530 N--DLYIRAVNAEFIYGYEYLGNSGRLVITPLTDRCYLTLTGALHLKFGGAPAGPAGTGK 1587
Query: 1877 TETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVA 1936
TETTKDLG+AL I VFNCS+Q+D+ + G +KGLA GAW CFDEFNRI +EVLSVVA
Sbjct: 1588 TETTKDLGKALAIQTVVFNCSDQLDFMAMGKFFKGLASAGAWACFDEFNRIDIEVLSVVA 1647
Query: 1937 VQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMV 1996
Q+ +IQ A + + + F F G EI L PS +FITMNPGYAGRTELP+NLK+LFRP AM+
Sbjct: 1648 QQITTIQKAQQQRVERFMFEGVEIPLVPSCAVFITMNPGYAGRTELPDNLKALFRPVAMM 1707
Query: 1997 VPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGS 2056
VPD+ +I EI L + GF EA LA+K T ++L E LS QDHYD+G+RA+K+V+ AG+
Sbjct: 1708 VPDYAMITEISLYSFGFNEASVLAKKITTTFKLSSEQLSSQDHYDFGMRAVKTVISAAGN 1767
Query: 2057 LKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEAL-- 2114
LKR +P E+ + +R++RD N+PK + +D+ +F G++ DLFP + + D ++ L
Sbjct: 1768 LKRENPSMNEELICLRAIRDVNVPKFLQEDLKLFSGIVSDLFPTI---KEEDTDYGILDE 1824
Query: 2115 -VRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKR 2173
+R+A + L+ + F+ K +QL E VRH + +VG G+GKS R L +K
Sbjct: 1825 AIREACRNSNLKDVEGFLTKCIQLYETTVVRHGLMLVGPTGSGKSTCYRVLAAAMTSLKG 1884
Query: 2174 RPV----------WTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHDGPKW 2223
+P + LNPK++T +L+G + T EW DG+FSS +R A + KW
Sbjct: 1885 QPSISGGMYEAVNYYVLNPKSITMGQLYGEFDLLTHEWTDGIFSSFIRAGAITSDTNKKW 1944
Query: 2224 ILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAG 2283
+ DG +D +WIE++NTV+DDNK L L+S E I L M ++FE+ L A+PATVSR G
Sbjct: 1945 YMFDGPVDAIWIENMNTVLDDNKKLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCG 2004
Query: 2284 ILYINPADLGWNPPVSSWIEKRE--IQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPE 2341
++Y+ P+ LG P + W+ K ++ + LF +L + +R+ K++I
Sbjct: 2005 MVYLEPSILGLMPFIECWLRKLPPLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTN 2064
Query: 2342 QSMVQMVCHLLECLLT-------TEDIPADCPK---EIYEHYFVFAAIWAFGGAMVQDQL 2391
++ + LL+C + IP++ E+ E +F+F+ IW+ G
Sbjct: 2065 CNLTMSLLKLLDCFFKPFLPREGLKKIPSEKLSRIVELIEPWFIFSLIWSVGATGDSSG- 2123
Query: 2392 VDYRAEFSKWWLTEFK----TVKFPSQGTIFDYYI---------DPETKKFE-------P 2431
R FS W + + T+ FP +G +FDY + D E ++ E
Sbjct: 2124 ---RTSFSHWLRLKMENEQLTLLFPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVK 2180
Query: 2432 WSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAK 2491
W F P+ +V T +T+++ + ++ L+ ++PV+ +G GTGK++ + K
Sbjct: 2181 WMDSSAPFTMVPDTNYCNIIVPTMDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDK 2240
Query: 2492 LASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPE 2551
L Y+ + F+ T++ Q ++ L+K+ +GPP + I+FIDD+NMP
Sbjct: 2241 LLKNLALDYISHFLTFSARTSANQTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPA 2300
Query: 2552 VDAYGTVQPHTIIRQHLDYGHWYDRSKL-SLKEITNVQYVSCMNPTAGS-FTINPRLQRH 2609
++ YG P ++RQ +D+G WYDR + + K + ++ +V M P G T+ PRL RH
Sbjct: 2301 LETYGAQPPIELLRQWMDHGGWYDRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRH 2360
Query: 2610 FSVFVLSFPGADALSS--IYSIILTQHLKLGNFPASLQKSIP----------PLIDLALA 2657
F+ LSF D +S I+S IL L S ++ +P PL++ +
Sbjct: 2361 FN--YLSFAEMDEVSKKRIFSTILGNWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIM 2418
Query: 2658 FHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRD 2717
+ I + LPT K HY FNLRD + +FQG+L + V+ L+RL+ HE+ RV+RD
Sbjct: 2419 VYATITSQLLPTPAKSHYTFNLRDLSKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRD 2478
Query: 2718 KMVEEKDFDLFDKIQTEVLKKTFDDIEDPVEQT--QSPNLYCHFAN-GIGEPKYMPVQSW 2774
++V E+D FD ++LK+ + E + P LY F + G Y + S
Sbjct: 2479 RLVNEEDRSWFD----QLLKRCMEQWEVTFNKVCPFQPILYGDFMSPGSDVKSYELITSE 2534
Query: 2775 ELLTQTLVEALENHNEVNTV-MDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQS 2833
+ Q + E +E++N++NT + LVLF DAM H+C I+R L GNALL+GVGGSG+ S
Sbjct: 2535 SKMMQVIEEYIEDYNQINTAKLKLVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSS 2594
Query: 2834 LTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFL 2893
LTRLA+ ++ + FQI L K Y + +++ D+ + LKAG++NL FL +D Q+ +E FL
Sbjct: 2595 LTRLASHMAEYECFQIELSKNYGMSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFL 2654
Query: 2894 VLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTL 2953
IN++L SG+IP+LY+ DE + I+S +R ++ QGL + N + R+R + + L
Sbjct: 2655 EDINNVLNSGDIPNLYTADEQDQIVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVL 2714
Query: 2954 CFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVK--QSI 3011
C SP+G R R R+FP++VNC I WF+EWP +AL+SV+ FL +E + + Q +
Sbjct: 2715 CMSPIGEVFRARLRQFPSLVNCCTIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGL 2774
Query: 3012 SKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLEN 3071
+ ++H SV++ YL+ R+NY TPKS+LE + ++ L+ + + ELK R+++
Sbjct: 2775 IQVCVYIHQSVSKKCIEYLAELTRHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKS 2834
Query: 3072 GLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQK 3131
GL KL TS V ++ L + L++ +D ++ + V+T A+A+E
Sbjct: 2835 GLDKLLRTSEDVAKMQEDLESMHPLLEEAAKDTMLTMEQIKVDT-------AIAEETRNS 2887
Query: 3132 VAVIMLEVKQKQK-------DCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLA 3184
V ++ +K K D ++DL +A PAL AA A+L LNK ++TE+++ PP
Sbjct: 2888 VQTEEIKANEKAKKAQAIADDAQKDLDEALPALDAALASLRNLNKNDVTEVRAMQRPPPG 2947
Query: 3185 VSNVSAAVMVLMAPRGRVPK-----------DRSWKAAKVTMAKVDGFLDSLINFNKENI 3233
V V AV ++ +G PK D W+ K + FL+SL F+K+NI
Sbjct: 2948 VKLVIEAVCIM---KGIKPKKVPGEKPGTKVDDYWEPGKGLLQDPGHFLESLFKFDKDNI 3004
Query: 3234 HENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKAT 3293
+ +KAI+PY+ + EF P +A S A +C WV + +++ V VEPKRQAL +A
Sbjct: 3005 GDVVIKAIQPYIDNEEFQPATIAKVSKACTSICQWVRAMHKYHFVAKAVEPKRQALLEAQ 3064
Query: 3294 ADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVG 3353
DL Q L K ++ + + +A + A++ + K + + + E + A +L+
Sbjct: 3065 DDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELELKCEQCEQRLGRAGKLIN 3124
Query: 3354 GLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQL 3413
GL+ E VRW + V+N + + GD+L+ F++YLG FT +YR L D +W L
Sbjct: 3125 GLSDEKVRWQETVENLQYMLNNISGDVLVAAGFVAYLGPFTGQYRTVLYD-SWVKQLRSH 3183
Query: 3414 KTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGI 3473
P P L + L + + +WQ GLP D +SVEN I +RW +DPQ Q
Sbjct: 3184 NVPHTSEPTL--IGTLGNPVKIRSWQIAGLPNDTLSVENGVINQFSQRWTHFIDPQSQAN 3241
Query: 3474 KWIKNKYGED-LRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKK 3532
KWIKN ++ L V ++ + +L+ +E A+ G L+EN+ E +DP L P+L ++ K+
Sbjct: 3242 KWIKNMEKDNGLDVFKLSDRDFLRSMENAIRFGKPCLLENVGEELDPALEPVLLKQTYKQ 3301
Query: 3533 --GRFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAV 3590
+K+GD Y+ FR+ + TKL NPHY PE+ + TLINFT++ GLEDQLL V
Sbjct: 3302 QGNTVLKLGDTVIPYHEDFRMYITTKLPNPHYTPEISTKLTLINFTLSPSGLEDQLLGQV 3361
Query: 3591 VSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQT 3650
V+ ERPDLE+ K+ L + LK +ED +L RLSS+ GN + + L++ LE +K
Sbjct: 3362 VAEERPDLEEAKNQLIISNAKMRQELKDIEDQILYRLSSSEGNPVDDMELIKVLEASKMK 3421
Query: 3651 AAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVF 3710
AAE++ KV+ A+ TE I+ R Y P A R +L+F ++DL+ + PMYQ+SL+ F +F
Sbjct: 3422 AAEIQAKVRIAEQTEKDIDLTRMEYIPVAIRTQILFFCVSDLANVDPMYQYSLEWFLNIF 3481
Query: 3711 QKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVN 3770
+ + ++L++R++N+ +T+S+Y R LFE KL + L +I++ ++N
Sbjct: 3482 LSGIANSERADNLKKRISNINRYLTYSLYSNVCRSLFEKHKLMFAFLLCVRIMMNEGKIN 3541
Query: 3771 AVELDFLLRS---PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKF 3827
E +LL + T +P ++LS +AW + LS++ FS+ D ++
Sbjct: 3542 QSEWRYLLSGGSISIMTENPAP-DWLSDRAWRDILALSNLPTFSSFSSDFVKHLSEFRVI 3600
Query: 3828 VESECPEKEKLPQEW-KNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDF 3886
+S P +E LP W + Q+L +LR +R D++T A++DFV L +++ + +
Sbjct: 3601 FDSLEPHREPLPGIWDQYLDQFQKLLVLRCLRGDKVTNAMQDFVATNLEPRFIEPQTANL 3660
Query: 3887 ATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAAL 3946
+ F++S TP+ F+LSPG DP D+ ++ + ++ +SLGQGQ AEA +
Sbjct: 3661 SVVFKDSNSTTPLIFVLSPGTDPAADLYKFAEEMKF---SKKLSAISLGQGQGPRAEAMM 3717
Query: 3947 DLAAKKGHWVILQNIHLVAKWLSTLEKKLEE-HSENSHPEFRVFMSAEPAPSPEGHIIPQ 4005
+ ++G WV QN HL W+ LE+ +E + + H +FR+++++ P+ + P
Sbjct: 3718 RSSIERGKWVFFQNCHLAPSWMPALERLIEHINPDKVHRDFRLWLTSLPS-----NKFPV 3772
Query: 4006 GILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERR 4065
IL+N K+T EPP G+ ANL K+ + +D L C + EFKS+L +LC FH ERR
Sbjct: 3773 SILQNGSKMTIEPPRGVRANLLKSYSSLGEDFLNSCHKVMEFKSLLLSLCLFHGNALERR 3832
Query: 4066 KFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRR 4125
KFGP G+N Y F GDL I ++ L FL+ +PY L+Y GEI YGG +TDDWDRR
Sbjct: 3833 KFGPLGFNIPYEFTDGDLRICISQLKMFLDEYDDIPYKVLKYTAGEINYGGRVTDDWDRR 3892
Query: 4126 LCRTYLGEFIRPEMLEGELSLAPG---FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPN 4182
L +F P++L E S + +P D +GY YI + + P ++GLH N
Sbjct: 3893 CIMNILEDFYNPDVLSPEHSYSASGIYHQIPPTYDLHGYLSYIKSLPLNDMPEIFGLHDN 3952
Query: 4183 AEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELM 4242
A I F + L T+++LQP+ S A REE V+ + + IL +V + N+ +M
Sbjct: 3953 ANITFAQNETFALLGTIIQLQPKSSSA---GSQGREEIVEDVTQNILLKVPEPINLQWVM 4009
Query: 4243 AK----VEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALY 4298
AK EE ++V QE R N L + I ++L++L LKG + M+S +E + +LY
Sbjct: 4010 AKYPVLYEESMNTVLV--QEVIRYNRLLQVITQTLQDLLKALKGLVVMSSQLELMAASLY 4067
Query: 4299 FDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTA 4358
+ VPE W+ +AYPS L++W DLL R+ L+AW D +P+ W++GFF PQ+FLT
Sbjct: 4068 NNTVPELWSAKAYPSLKPLSSWVMDLLQRLDFLQAWIQD-GIPAVFWISGFFFPQAFLTG 4126
Query: 4359 IMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEA 4418
+Q+ ARK +D ++ + + E P+ G YIHGLF+EGA WD +A + E+
Sbjct: 4127 TLQNFARKFVISIDTISFDFKVMFEAPSELTQRPQVGCYIHGLFLEGARWDPEAFQLAES 4186
Query: 4419 KLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTK 4469
+ K+L M V+++ P K + Y CP+YKT R T YV + T
Sbjct: 4187 QPKELYTEMAVIWLLPTPNRKAQDQDFYLCPIYKTLTRAGTLSTTGHSTNYVIAVEIPTH 4246
Query: 4470 ENPSKWVLAGVALL 4483
+ W+ GVAL+
Sbjct: 4247 QPQRHWIKRGVALI 4260
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 1941 bits (5029), Expect = 0.0
Identities = 1194/3573 (33%), Positives = 1893/3573 (52%), Gaps = 200/3573 (5%)
Query: 1055 LSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLN---------IIKRWSL 1105
+ F + SYE + +E+C+ + K+ + I+ + + ++KR +
Sbjct: 509 VDNFLAENHSYEKIIDEICKYQ--KLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADI 566
Query: 1106 LFKQHLV----DHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQS- 1160
+ + L DH + D F + +E L + L+E+ ++ V+
Sbjct: 567 ICGKLLAKMFRDHQEVNTRLCDEFERIAEKALSTPPNTAE---LMEMKAYIQKVEVTDMI 623
Query: 1161 NTDEMFEPLKQTIELLKTY------EQELPETVFKQLEELPEKWNNIKKVAITVKQQVAP 1214
++ K + L Y + L +VF+ + E + +K+ +K+++
Sbjct: 624 ELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWYGRMGEIFEEHRKI---IKEKIEQ 680
Query: 1215 LQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQM-----------LDARHI 1263
Q L+ RC F E + + +Q E + F + Q LD
Sbjct: 681 YQEG----LKLRCERFVEELESYAKQ--SEEFYSFGDLQDVQRYLKKAQILNGKLDLAAD 734
Query: 1264 EIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTP 1323
+I+Q + + S+ Y Q ++ + + L++T +S+ AW P
Sbjct: 735 KIEQFNAEEEAFGWLPSV-------YPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTEGP 787
Query: 1324 WRNINVEAMELECKQFARHIRNLDKEVR----AWDAFTGLESTVWNTLSSLRAVAELQNP 1379
+ +N + +E + + R + L+K A + S V + + + + NP
Sbjct: 788 YHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVRSKVEDFKQHIPLIQVICNP 847
Query: 1380 AIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKE 1439
+R RHW + G D+T++ L + L Y D GI + A+KE +EK +++
Sbjct: 848 GLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAASKEYSLEKAMEK 907
Query: 1440 LQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQ 1499
+ T W +EF + T +L S +++ +L+D+ ++ Q + S ++ + +++ W+
Sbjct: 908 MITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFIKPYEKQMREWE 967
Query: 1500 KKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQK 1559
KL + ++ W +VQ TW +LE IF+ S DI +Q+P++ +RF +D ++++ +
Sbjct: 968 GKLLLLQEILDEWLKVQATWLYLEPIFS-SPDIMSQMPEEGRRFTAVDKTWRDIMRSVMQ 1026
Query: 1560 IPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNG 1619
+V+ + E+L+ L L K L EYL+ KRL FPRF+FLS+ +LL+ILS
Sbjct: 1027 DKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLSNDELLEILSET 1086
Query: 1620 TAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIW 1679
P +VQ HL K F+ +AK+ F K+S G + E + GQVE W
Sbjct: 1087 KDPTRVQPHLKKCFEGIAKVEFTETLDITHMKSSEG---EVVELIEIISTAKARGQVEKW 1143
Query: 1680 LNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLE 1739
L + M ++ + AY + R W+ D P Q L +QI+WT EV A +
Sbjct: 1144 LVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTKEVQTA---IP 1200
Query: 1740 EGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVD 1799
G + A++ Y K Q+ ++T++ G+LS +R + + +DVHARDV++ ++ + +
Sbjct: 1201 MGIK-ALEQYLKTCNRQIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDVLSSLVKKNIS 1259
Query: 1800 NAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQS 1859
+ F WLSQLR+ W + H + +A Y YEYLGN+PRLVITPLTDRCY TL +
Sbjct: 1260 DDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITPLTDRCYRTLFGA 1317
Query: 1860 LHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWG 1919
LHL + GAP GPAGTGKTETTKDL +A+ VFNCS+ +DY + G +KGL GAW
Sbjct: 1318 LHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGKFFKGLLSCGAWA 1377
Query: 1920 CFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGR 1979
CFDEFNRI +EVLSVVA Q+ +IQ I F G E+ L+P+ +FITMNPGYAGR
Sbjct: 1378 CFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCAVFITMNPGYAGR 1437
Query: 1980 TELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDH 2039
+ELP+NLK+LFR AM+VPD+ +I EI+L + GF+ A+ L+ K + Y+LC E LS Q H
Sbjct: 1438 SELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATYRLCSEQLSSQHH 1497
Query: 2040 YDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFP 2099
YD+G+RA+KSVL AG+LK P+ E+ +L+RS+ D N+PK ++ D+P+F G+ DLFP
Sbjct: 1498 YDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDLPLFEGITSDLFP 1557
Query: 2100 ALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQ 2159
+ +P+ + A ++ + LQ F K++Q+ E++ VRH +VG GK+
Sbjct: 1558 GVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGFMIVGEPFGGKTS 1617
Query: 2160 VLRSLHKTYQ------IMKRRPVW-TDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRE 2212
R L +M+ V T LNPK+VT +L+G + + EW DG+ + R
Sbjct: 1618 AYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHEWSDGVLAVSFRA 1677
Query: 2213 LANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLR 2272
A+ KW++ DG +D +WIE++NTV+DDNK L L S E I ++P M L+FE L
Sbjct: 1678 FASSVTPDRKWLIFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQMSPQMNLIFEPMDLE 1737
Query: 2273 TATPATVSRAGILYINPADLGWNPPVSSWIEKREIQT---ERANLTILFDKYLPTCLDTL 2329
A+PATVSR G++Y+ P LGW P + SW+ ++ + LFD+ +P ++ +
Sbjct: 1738 VASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSVIQKEFIMGLFDRMVPVSVEFI 1797
Query: 2330 RTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPK----------EIYEHYFVFAAI 2379
R K++ P + ++V+ + +L++C + D AD K + E F+F+ I
Sbjct: 1798 RKHTKELSPTSDTNLVRSLMNLIDCFM---DDFADEVKLKERNDRETYSLLEGIFLFSLI 1854
Query: 2380 WAFGGAMVQDQLVDY--------RAEFSKWWLTEFK-------------TVKFPSQGTIF 2418
W+ G + D + + + S FK TV FP +GTI+
Sbjct: 1855 WSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTEQTSSKALTVPFPEKGTIY 1914
Query: 2419 DY-YIDPETKKFEPWSKLVPQFEFDP-EMPLQACLVHTSETIRVCYFMERLMARQRPVML 2476
DY ++ K+EPW K + + P ++ +V T +TIR ME L Q+P +
Sbjct: 1915 DYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTIRYSALMELLTTHQKPSIF 1974
Query: 2477 VGTAGTGKSV-LVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPP 2535
VG GTGKSV + L L+ E Y + F+ TT+A Q ++ L+K+ +GPP
Sbjct: 1975 VGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQNIVMSKLDKRRKGVFGPP 2034
Query: 2536 GNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNP 2595
K+++ F+DD+NMP + YG P ++RQ LD+ +WYD S+ ++ ++Q + M P
Sbjct: 2035 LGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLKDCSMIKLVDIQIMCAMGP 2094
Query: 2596 TAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKL-GNFPASLQKSIPPLID 2653
G + PR RHF++ ++ ++ +I+S ILT HL++ FP +++
Sbjct: 2095 PGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLEICYKFPDEFLDLTTQIVN 2154
Query: 2654 LALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNR 2713
+ +++ LPT K HY+FNLRDF+ + QG+ S E ++T + RL++HE R
Sbjct: 2155 GTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPETTETTEVIKRLWVHEVLR 2214
Query: 2714 VYRDKMVEEKDFD-LFDKIQTEVLKKTFDDIEDPVEQTQSPN------------LYCHFA 2760
VY D++++ D L + IQ + ++D + ++ N ++C F
Sbjct: 2215 VYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDNDGMVEADDLRSLMFCDFH 2274
Query: 2761 NGIGE-PKYMPVQSWELLTQTLVEALENHNEVN-TVMDLVLFEDAMRHVCHINRILESPR 2818
+ E Y + + L + LE +N ++ M+LVLF A+ H+ I+RIL+ PR
Sbjct: 2275 DPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLFRFAIEHISRISRILKQPR 2334
Query: 2819 GNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNT 2878
+ALLVGVGGSG+QS+TRLAA ++ VFQ+ + KGY ++ DL + K +
Sbjct: 2335 SHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEWHEDLKVILRKCAEGEMQG 2394
Query: 2879 VFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQGLVDNREN-- 2936
VFL TD Q+ +E FL +++LL +GEIP+L++ DE + I +R + + +
Sbjct: 2395 VFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDKMRQLDRQRDKTKQTDGSP 2454
Query: 2937 --CWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSL 2994
+ FID R QL V L SP+G+ R R RKFPA+VNC I WF WP+ AL++V+
Sbjct: 2455 IALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCCTIDWFQSWPEDALQAVAS 2514
Query: 2995 RFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSL 3054
RFL+ E E I +F HTS S+S+ QRYNY TP S+LE I ++ L
Sbjct: 2515 RFLEEIEMSEEIRDGCIDMCKSF-HTSTIDLSKSFFVELQRYNYVTPTSYLELISTFKLL 2573
Query: 3055 LHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVE 3114
L + R E+ +R E GL KL S S+QV ++ +L A +LK +++ D+++ ++ E
Sbjct: 2574 LEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVASKEVDEMMIMIEKE 2633
Query: 3115 TDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTE 3174
+ +V++ + + +E + K + +C+ DLA A P L +A AAL+TL ++T
Sbjct: 2634 SVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPILESALAALDTLTAQDITV 2693
Query: 3175 LKSFGSPPLAVSNVSAAVMVLMA--------PRGRVPK-DRSWKAAKVTMAKVDGFLDSL 3225
+KS SPP V V A+ +L P G K + W AK + + FL SL
Sbjct: 2694 VKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDFWGPAKRLLGDM-RFLQSL 2752
Query: 3226 INFNKENIHENCLKAIRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEP 3284
++K+NI + IR Y+ +P+F PE + S AA GLC WVI + + +V V P
Sbjct: 2753 HEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLCKWVIAMDSYDKVAKIVAP 2812
Query: 3285 KRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVT 3344
K+ L A +L A + L +A + + + LA+L E K + + ++ +
Sbjct: 2813 KKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLELNKQKKADLENQVDLCSKK 2872
Query: 3345 ISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDR 3404
+ A +L+GGL E RW+ Q L GDIL+ + ++YLG FT YRQ+ +
Sbjct: 2873 LERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGVVAYLGAFTSTYRQN-QTK 2931
Query: 3405 TWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPL 3464
W IP + + L + + W GLP+D S++N I++N RWPL
Sbjct: 2932 EWTTLCK--GRDIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDSFSIDNGIIIMNARRWPL 2989
Query: 3465 MVDPQLQGIKWIKN-KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGP 3523
M+DPQ Q KWIKN + L V ++ + Y++ +E ++ G VL+EN+ E +DP+L P
Sbjct: 2990 MIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGTPVLLENVGEELDPILEP 3049
Query: 3524 LLGREVIKKG--RFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDG 3581
LL ++ K+G I++GD EY P FR + TKL NPHY PE + TL+NF +T +G
Sbjct: 3050 LLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLPETSVKVTLLNFMITPEG 3109
Query: 3582 LEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLV 3641
++DQLL VV+ ERPDLE+ K L Q K LK +ED +L LSS+ GN L + +
Sbjct: 3110 MQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKILEVLSSSEGNILEDETAI 3169
Query: 3642 ENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQF 3701
+ L +K A E+ +K + A+ TE KI+ R YRP A +S+L+F + DL+ I PMYQ+
Sbjct: 3170 KILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSILFFSLADLANIEPMYQY 3229
Query: 3702 SLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQ 3761
SL F +F ++E + E L +R+ L D T+S+Y R LFE DKL + LT
Sbjct: 3230 SLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCRSLFEKDKLLFSFCLTIN 3289
Query: 3762 ILLMNREVNAVELDFLLRSPV--QTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEG 3819
+LL R +N E FLL + A+ +L ++W + L + F + R+
Sbjct: 3290 LLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEICRLDDLPAFKTIRREFMR 3349
Query: 3820 SAKSWKKFVESECPEKEKLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKY 3878
WKK +S P E P+EW++K QR+ ++R +RPD++ L++F+ +LG +
Sbjct: 3350 LKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDKVIPMLQEFIINRLGRAF 3409
Query: 3879 VVGRALDFATSFEESGPATPMFFILSPGVDP----LKDVESQGRKLGYTFNNQNFHNVSL 3934
+ D A +F +S P+ F+LSPG DP LK + QG + ++SL
Sbjct: 3410 IEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAALLKFADDQG------YGGSKLSSLSL 3463
Query: 3935 GQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHS-ENSHPEFRVFMSAE 3993
GQGQ +A L+ A K+G WV+LQN HL W+ TLEK EE S E++HP+FR+++++
Sbjct: 3464 GQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEELSPESTHPDFRMWLTSY 3523
Query: 3994 PAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKA--LDNFTQ-DTLEMCSRETEFKSI 4050
P+P+ P +L+N +K+TNE P G+ AN+ ++ +D + + C + EFK +
Sbjct: 3524 PSPN-----FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPISDPEFFGSCKKPEEFKKL 3578
Query: 4051 LFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFG 4110
L+ LC+FHA+V ERRKFGP GWN Y FN DL ISV L+ FL ++PY+ LRY+ G
Sbjct: 3579 LYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMFLNQYEELPYEALRYMTG 3638
Query: 4111 EIMYGGHITDDWDRRLCRTYLGEFIRPEMLEG---ELSLAPGFPLPGNMDYNGYHQYIDA 4167
E YGG +TDDWDRR R+ L +F PE++E + + + +P + D+ Y +Y
Sbjct: 3639 ECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIYFVPPSGDHKSYIEYTKT 3698
Query: 4168 ELPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGA-TREEKVKALLE 4226
+P ++G++ NA+I ++ LF +L Q R + GAGA + +E V +
Sbjct: 3699 LPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSA----GAGAKSSDEVVNEVAS 3754
Query: 4227 EILERVTDEFNIPELMAKVEERTPYI----VVAFQECGRMNILTREIQRSLRELELGLKG 4282
+IL ++ + F+I M + T Y V QE GR N L + I+ S ++ +KG
Sbjct: 3755 DILGKLPNNFDIEAAMRRYP--TTYTQSMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKG 3812
Query: 4283 ELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPS 4342
M++ +E + +++ +PE W ++YPS L ++ D L R+K L+ W + P
Sbjct: 3813 LAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARLKFLQQWY-EVGPPP 3871
Query: 4343 TVWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLF 4402
WL+GFF Q+FLT Q+ ARK P+D + ++ + +E++ PP +G +IHGLF
Sbjct: 3872 VFWLSGFFFTQAFLTGAQQNYARKYTIPIDLLGFDYEVMED--KEYKHPPEDGVFIHGLF 3929
Query: 4403 MEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR------ 4456
++GA W+ + + E+ K L +PVM++K R Y P+YKTS+R
Sbjct: 3930 LDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVAPLYKTSERRGVLST 3989
Query: 4457 ---GPTYVWTFNLKTKENPSKWVLAGVALLLQI 4486
+V L + + W+ GVALL Q+
Sbjct: 3990 TGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQL 4022
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 1930 bits (5001), Expect = 0.0
Identities = 1170/3539 (33%), Positives = 1890/3539 (53%), Gaps = 118/3539 (3%)
Query: 1010 FSQYSYLYVEDRKEVLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLY 1069
F +Y L+ EDR + +FL N P L++ + +I Y T
Sbjct: 1007 FQKYKTLWTEDRDVKVKEFLA--------------------NNPSLTEIRSEILHYATFE 1046
Query: 1070 EEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKS 1129
+E+ L+PI V G +++ P K +L K W +L ++L + ++ + AFI +
Sbjct: 1047 QEIDELKPIIVV-GALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSYMIAFINEY 1105
Query: 1130 ESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFK 1189
L + + D + M L +++ + D P+++ +L +E E+ + +
Sbjct: 1106 LKKLSRPIR--DLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYAILNRFEVEVTKEESE 1163
Query: 1190 QLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRF 1249
++ L +N ++ A++V++ + +Q + L + F + F E + E P
Sbjct: 1164 AVDTLRYSFNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVFREDVINFAEAYELEGPM-V 1222
Query: 1250 DSIHPHQMLDARHI---EIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELW 1306
+I P + + I + + S LF + V DY+ L + RKE+ L++L+
Sbjct: 1223 PNIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELNLLQKLY 1282
Query: 1307 DTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNT 1366
V SSI + W ++++E + E +F R L K ++ W AF L+ + +
Sbjct: 1283 GLYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAFLDLKKRIDDF 1342
Query: 1367 LSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDT-TLAHLLQLQLHHYEDEVRGIVD 1425
S + + N A+++RHW ++ + TG F ++ D+ L ++++ L ++D++ I
Sbjct: 1343 SESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDSFCLRNIMEAPLLKHKDDIEDICI 1402
Query: 1426 KAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDE--DLIEVLEDNQVQLQNLV 1483
A KE +E L ++ W + LL E ++I ++ED+ + L +L+
Sbjct: 1403 SAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLL 1462
Query: 1484 MSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRF 1543
++Y A F + + W KLST +I W VQ W +LE++F G DI QLPQ++KRF
Sbjct: 1463 SNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGG-DIAKQLPQEAKRF 1521
Query: 1544 EGIDIDFKELAYDAQKIPNVVQT-TNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFP 1602
+ ID + ++ A + PNV+ + + L + +L +C+K+L YL+ KRL FP
Sbjct: 1522 QNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFP 1581
Query: 1603 RFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEE 1662
RF+F+S LL+IL + +Q HL + DN+ ++ F + + + S+E E
Sbjct: 1582 RFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFH----AKDYDRIMAVISREGE 1637
Query: 1663 YVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPRE--QWLFDHPAQVAL 1720
+ G VEIWL +L +++ + + + + +L PAQV L
Sbjct: 1638 KIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLSHFPAQVGL 1697
Query: 1721 TCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTIC 1780
Q+ WT + A ++ M+ +K + L TLI+ LSK DR K T+
Sbjct: 1698 LGIQMLWTHDSEEALRNAKDD-RKIMQVTNQKFLDILNTLISQTTHDLSKFDRVKFETLI 1756
Query: 1781 TIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNT 1840
TI VH RD+ ++ + + F WL Q R + +++ +I D F+Y E+LG T
Sbjct: 1757 TIHVHQRDIFDDLVKMHIKSPTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCT 1816
Query: 1841 PRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQM 1900
RLVITPLTDRCYITL Q+L + M GAPAGPAGTGKTETTKD+GR LG V VFNCS+QM
Sbjct: 1817 DRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQM 1876
Query: 1901 DYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFL-GEE 1959
D++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ + A +++K+ F F G+
Sbjct: 1877 DFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDC 1936
Query: 1960 ISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSL 2019
+ LNP GIF+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GF+E L
Sbjct: 1937 VDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVIL 1996
Query: 2020 ARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNI 2079
A+KF LY+LC+E L+KQ HYD+GLR I SVL GS KR P+ E ++MR LRD N+
Sbjct: 1997 AQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSIVMRGLRDMNL 2056
Query: 2080 PKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEE 2139
K+V +D P+F+ LI DLFP L + + V + L + LK+VQL E
Sbjct: 2057 SKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAVAHQVQIEGLINHPPWNLKLVQLYE 2116
Query: 2140 LLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATG 2199
VRH + +G +G+GK+ V+ L K R +NPKA+T ++FG ++ AT
Sbjct: 2117 TSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPHREMRMNPKAITAPQMFGRLDTATN 2176
Query: 2200 EWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLN 2259
+W DG+FS++ R+ +++LDG +D +WIE+LN+V+DDNK LTLA+ +RIP+
Sbjct: 2177 DWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMA 2236
Query: 2260 PTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFD 2319
P+ KLLFE+ ++ A+PATVSR G++YI+ + L W P + +W++KR Q E A L++
Sbjct: 2237 PSCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKKRTAQ-EAAVFLTLYE 2295
Query: 2320 KYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLL-TTEDIPADCPKEIYEHYFVFAA 2378
K ++ + + E + + +LLE L+ + E+ C + +++ FVF
Sbjct: 2296 KVFEDTYTYMKLNLNPKMQLLECNYIVQSLNLLEGLIPSKEEGGVSCVEHLHK-LFVFGL 2354
Query: 2379 IWAFGGAMVQDQLVDYRAEFSKWWLTEFKTVKFP--SQGTIFDYYIDPETKKFEPWSKLV 2436
+W+ GA+++ + + F + ++ + P S T++++Y+ + +E W+K +
Sbjct: 2355 MWSL-GALLELESREKLEAFLRQHESKLDLPEIPKGSNQTMYEFYV-TDYGDWEHWNKKL 2412
Query: 2437 PQFEF--DPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLAS 2494
+ + D + LV + IR + ++ + + + V+L G GT K+V+V A L
Sbjct: 2413 QPYYYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKK 2472
Query: 2495 LDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDA 2554
DPE L K++ F+ T M Q +E ++K+ G YGPPG +K+ FIDD+NMP ++
Sbjct: 2473 YDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINE 2532
Query: 2555 YGTVQPHTIIRQHLDYGHWYDRSKL-SLKEITNVQYVSCM-NPTAGSFTINPRLQRHFSV 2612
+G + I+RQ ++ Y K I +VQ ++ M +P G I RL+R F+V
Sbjct: 2533 WGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTV 2592
Query: 2613 FVLSFPGADALSSIYSIILTQHL-KLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGI 2671
F + P ++ I+ II + +F + + I L+ + Q LPT
Sbjct: 2593 FNCTLPSNASIDKIFGIIGCGYFDPCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPS 2652
Query: 2672 KFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKI 2731
KFHYIFNLRD + I+QG+L E S L+ L+ HE +RV D+ + +D F+
Sbjct: 2653 KFHYIFNLRDLSRIWQGMLTIKAEECASIPTLLSLFKHECSRVIADRFITPEDEQWFNAH 2712
Query: 2732 QTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGEPK--------------YMPVQSWELL 2777
T +++ D + F + EP Y + S++ L
Sbjct: 2713 LTRAVEENIG--SDAASCILPEPYFVDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFL 2770
Query: 2778 TQTLVEALENHNEV--NTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLT 2835
+ L NE+ T +DLV F+DAM H+ I+RI+ + GNALLVGVGGSGKQSL+
Sbjct: 2771 AEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLS 2830
Query: 2836 RLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVL 2895
RLA+FI+ +FQITL + Y + + DL +L AG F+ TD+++ DE FL
Sbjct: 2831 RLASFIAGYQIFQITLTRSYNVTNLTDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEY 2890
Query: 2896 INDLLASGEIPDLYSDDEVENIISNVRNEVKSQ--GLVDNRENCWKFFIDRIRRQLKVTL 2953
+N+LL+SGEI +L++ DE++ I + + +K + +N +++FI R R+ L V L
Sbjct: 2891 LNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVL 2950
Query: 2954 CFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGI-EPTVKQSIS 3012
CFSPVG K R RS KFP +++ + WF WP++AL +V+ FL + + +K+ +
Sbjct: 2951 CFSPVGEKFRARSLKFPGLISGCTMDWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVV 3010
Query: 3013 KFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENG 3072
+ M H V+++ +SY +R + TPKS+L FI Y+++ K + + ER+ G
Sbjct: 3011 ETMGLFHDMVSESCESYFQRYRRRAHVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIG 3070
Query: 3073 LLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKV 3132
L KL S V L LA +E EL + AD+++ V V ++ K E + K
Sbjct: 3071 LDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKA 3130
Query: 3133 AVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAV 3192
I+ E+ ++ E L A+PAL A+AALNT+ ++ ++ PP + + V
Sbjct: 3131 QKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCV 3190
Query: 3193 MVL---------MAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRP 3243
++L M P K SW + + GFL SL F K+ I+E ++ ++P
Sbjct: 3191 LLLFQKKIDPVTMDPEKSCCKP-SW-GESLKLMSATGFLWSLQQFPKDTINEETVELLQP 3248
Query: 3244 YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKL 3303
Y ++ E AGL SW + + FY + +V P + L K L A +L
Sbjct: 3249 YFNMDDYTFESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAEL 3308
Query: 3304 AAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWA 3363
+A + L K+ A+F+ A +K+ +A+ + A+ L+ GL+ E +RW
Sbjct: 3309 GKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWT 3368
Query: 3364 DAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPAL 3423
+ FK Q L GDILL T F+SYLG F + +R LL W L K IP T L
Sbjct: 3369 QQSKEFKAQINRLVGDILLCTGFLSYLGPFNQIFRNYLLKDQWEMELRARK--IPFTENL 3426
Query: 3424 DPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGE- 3482
+ + ML+D + W +GLP D +S++N I+ R+PL++DPQ QG WIK+K E
Sbjct: 3427 NLISMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKEN 3486
Query: 3483 DLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGRF--IKIGD 3540
DL+VT + K + +E +L G +LIE++ E +DP L +L + IK G +K+GD
Sbjct: 3487 DLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIHEELDPALDNVLEKNFIKSGTTFKVKVGD 3546
Query: 3541 KECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQ 3600
KEC+ F+L + TKL NP + PE+ A+ ++I+FTVT GLE+QLL V+ E+ +LE
Sbjct: 3547 KECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELEA 3606
Query: 3601 LKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQE 3660
+ L + K +K LED+LL +LS+ G+ + + L+ L TKQTAAEV +K+
Sbjct: 3607 ERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRTTKQTAAEVSEKLHV 3666
Query: 3661 AKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPD 3720
A TE+KIN A+E +RPAA R S+LYF++ ++S ++ MYQ SL F +F +++ R+
Sbjct: 3667 AAETEIKINAAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKS 3726
Query: 3721 ESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRS 3780
++R+ N+I+ +T+ V+ Y++RGL+E K ++ +T +I L V E L++
Sbjct: 3727 PLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHREFQALIKG 3786
Query: 3781 ----PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKE 3836
++ P ++ W + LS + +F+ + I + K WK + + + PE+E
Sbjct: 3787 GAALDLKACPPKPYRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEE 3846
Query: 3837 KLPQEWKNK-TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGP 3895
+P + + +L ++R+ PDR + R ++ + L KY L+ ++EES
Sbjct: 3847 IIPDGYNDSLDTCHKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDT 3906
Query: 3896 ATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHW 3955
TP+ LS G DP +++ +KL +S+GQGQEV A + ++ ++G W
Sbjct: 3907 RTPLICFLSMGSDPTNQIDALAKKL-----KLECRTISMGQGQEVHARKLIQMSMQQGGW 3961
Query: 3956 VILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKIT 4015
V+LQN HL +++ L + L +E S FRV+++ EP P +L+ S+K T
Sbjct: 3962 VLLQNCHLGLEFMEELLETLIT-TEASDDSFRVWITTEPHDR-----FPITLLQTSLKFT 4015
Query: 4016 NEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRS 4075
NEPP G+ A L + QD L++ S +K +L+ + + H+ V ERRKFGP GWN
Sbjct: 4016 NEPPQGVRAGLKRTFAGINQDLLDI-SNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIP 4074
Query: 4076 YPFNTGDLTISVNVLYNFL-EANAK--VPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLG 4132
Y FN+ D + SV + N L E + K V ++ +RY+ GE+ YGG +TDD+D+RL +
Sbjct: 4075 YEFNSADFSASVQFIQNHLDECDIKKGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFAR 4134
Query: 4133 EFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTS 4192
+ +M E G+ +P + Y +YI + ++P ++GLHPNA+I + + T+
Sbjct: 4135 VWFSEKMFEPSFCFYTGYKIPLCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTA 4194
Query: 4193 EKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEF---NIPELMAKVEERT 4249
+ T+ +QP++S G G TRE V L E++L ++ ++ + + K+
Sbjct: 4195 SAVLETITNIQPKESGG--GVGETREAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLN 4252
Query: 4250 PYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARR 4309
+ QE RM + ++ SL +L+L ++G + M+ ++ + + +Y +P+ W R
Sbjct: 4253 SMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRV 4312
Query: 4310 AYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNE- 4368
++ S+ L WF +LL R + W + P+ W+TGFFNPQ FLTA+ Q R ++
Sbjct: 4313 SWDSST-LGFWFTELLERNAQFSTWIFE-GRPNVFWMTGFFNPQGFLTAMRQEVTRAHKG 4370
Query: 4369 WPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMP 4428
W LD + + ++ ++ +EE SPP EG YI+GL+M+GA WD + G + E+ K L +P
Sbjct: 4371 WALDTVTIHNEVLRQTKEEITSPPGEGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLP 4430
Query: 4429 VMFIKAIPADKQDCRSVYSCPVYKTSQRGP-TYVWTFNLKTKENPSKWVLAGVALLLQI 4486
V+ I AI + +Y CP+YK +R T++ L+T +P W+L GVALL I
Sbjct: 4431 VLHIFAINSTAPKDPKLYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLCDI 4489
Score = 167 bits (423), Expect = 2e-40
Identities = 154/753 (20%), Positives = 330/753 (43%), Gaps = 46/753 (6%)
Query: 133 LAALFSEVVLPV-----LANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLP 187
LA +F VL L K + H+ E + R+ L I VK KT+
Sbjct: 58 LANIFLPAVLATNNWGALNQSKQGESEKHIFTETINRYLSFLDGARISIEGTVKLKTIDN 117
Query: 188 LPAGS----EKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQG 243
+ E++ A S SETV + +E ++ W Q++ VL ES Q +
Sbjct: 118 VNFSKLHTFEEVTAAASNSETV---------HQLEEVLMVWYKQIEQVLI-ESEQMRKEA 167
Query: 244 ENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAAL 303
+ P ELE WK YI Q++ + + + +L+ S ++ + +
Sbjct: 168 GDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTA 227
Query: 304 AEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQ 363
E++D +L L++ + L N + + ++ L++ + +I + Y + R+T L
Sbjct: 228 NESKDNVRYLYTLEKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFI 287
Query: 364 EICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQ 423
++ N ++ Y++ L +E+ L+ + D + FK E+Q E+
Sbjct: 288 KVTNQMVTACKAYITDGGLNHVWDQETPVVLKKIQDCIFLFK-EYQASFHKTRKLISESS 346
Query: 424 EVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMH 483
K ++ +F + + F +L + ++ + L N+ + + M
Sbjct: 347 GEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTL---------SNSTIEGIDIMA 397
Query: 484 EEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHA 543
+F+ +Y+ + D L + T+F+ D +F K+ L+ ++ +F + A
Sbjct: 398 IKFRNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKILSSQQA 457
Query: 544 FKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKN 603
+LL L P + + + ++Q + +LDA + +Y H Q++ P+ +N
Sbjct: 458 LQLLQ-RFQKLNIPCLGLEINHTIERILQYYVAELDATKKLY--HSQKDD----PPLARN 510
Query: 604 MPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLY 663
MP +AG + W ++L +RI P + F + + S +GK + ++Y + +L ++E +
Sbjct: 511 MPPIAGKILWVRQLYRRISEPINYFFK-NSDILSSPDGKAVIRQYNKISYVLVEFEVVYH 569
Query: 664 EDWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAA 723
W R +S+ Y L L R PET ++ +NF+P+++ V++E + ++ +PE A
Sbjct: 570 TAWIREISQ-LHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKL-DVPEQAK 627
Query: 724 AMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKT 783
+ + L+ + +Y+++ + + V L+ +++ ++ LR L W +
Sbjct: 628 RLLKLESKLKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSS 687
Query: 784 EGICDYVTEITSSIHDLEQRIQKTKDNVE-----EIQNIMKTWVTPIFKTKDGKRESLLS 838
+ + E+ + Q ++K D E ++ I KT + + ++ K E +L+
Sbjct: 688 LTLESFFQEVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLT 747
Query: 839 LDDRHDRMEKYYNLIKESGLKIHALVQENLGLF 871
L++ + + ++ +++ + V+E + +F
Sbjct: 748 LNETYTK--EWADILNHKSKHVEEAVRELISIF 778
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 1923 bits (4982), Expect = 0.0
Identities = 1158/3432 (33%), Positives = 1838/3432 (53%), Gaps = 152/3432 (4%)
Query: 1170 KQTIELLKTYEQELPETVFK---QLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLR-- 1224
K+ + L++ ++ TVFK QL + E+ + A + Q+ + N LL
Sbjct: 720 KELVSLIEFLKKSSAVTVFKLRRQLRDASERLEFLMDYA-DLPYQIEDIFDNSRNLLLHK 778
Query: 1225 ---------QRCTAFDAEQQQFW---EQFHKEAPFRFDSI-HPHQMLDARHIEIQQMEST 1271
+RC+ F+ + + E F K + + H + L+ + + +
Sbjct: 779 RDQAEMDLIKRCSEFELRLEGYHRELESFRKREVMTTEEMKHNVEKLNELSKNLNRAFAE 838
Query: 1272 MASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEA 1331
I++ L E Y L+ K ++LW T + W P +N E
Sbjct: 839 FELINKEEELLEKEKSTYPLLQAMLKNKVPYEQLWSTAYEFSIKSEEWMNGPLFLLNAEQ 898
Query: 1332 MELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQ----NPAIRERHWR 1387
+ E R L K + A L V + + + NP +++RHW+
Sbjct: 899 IAEEIGNMWRTTYKLIKTLSDVPAPRRLAENVKIKIDKFKQYIPILSISCNPGMKDRHWQ 958
Query: 1388 QLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGM 1447
Q+ + G + T L+++L+ + +++ I A+KE +EK L ++ W +
Sbjct: 959 QISEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAAASKEYSLEKNLDRMKLDWVNV 1018
Query: 1448 EFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDA 1507
F + + T+ +LC+ +D+ +L+D+ ++ Q + S ++ E W++KL +
Sbjct: 1019 TFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSPFIKPIEAECRKWEEKLIRIQD 1078
Query: 1508 VISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTT 1567
+ W + Q TW +LE IF+ SEDI AQ+P++ ++F +D +K L A K ++
Sbjct: 1079 NLDAWLKCQATWLYLEPIFS-SEDIIAQMPEEGRKFGIVDSYWKSLMSQAVKDNRILVAA 1137
Query: 1568 NKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQR 1627
++P + EKL++ L +K L +YL+ KRL FPRF+FLS+ +LL+ILS P +VQ
Sbjct: 1138 DQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPLRVQP 1197
Query: 1628 HLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSE---PCDCSGQVEIWLNHVL 1684
HL K F+ +AK+ F + +GM S E+E V F + P + G VE WL V
Sbjct: 1198 HLKKCFEGIAKLEFTDNLE------IVGMISSEKETVPFIQKIYPANAKGMVEKWLQQVE 1251
Query: 1685 GHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYES 1744
M A++R + G+ AY + PR W+ P QV + + I+WT EV A A E+
Sbjct: 1252 QMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSSIFWTQEVSQALA------EN 1305
Query: 1745 AMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAF 1804
+ D+ KK Q+ ++ ++ G+LS G R + + IDVHARDVVAK+ +V + F
Sbjct: 1306 TLLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDVHARDVVAKLSEDRVSDLNDF 1365
Query: 1805 LWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTM 1864
W+SQLR+ W K I + LY YEYLGN+PRLVITPLTDRCY TL +L L +
Sbjct: 1366 QWISQLRYYW--VAKDVQVQIITTEALYGYEYLGNSPRLVITPLTDRCYRTLMGALKLNL 1423
Query: 1865 SGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEF 1924
GAP GPAGTGKTETTKDL +AL VFNCS+ +DYK+ G +KGLAQ GAW CFDEF
Sbjct: 1424 GGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDYKAMGKFFKGLAQAGAWACFDEF 1483
Query: 1925 NRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTELPE 1984
NRI VEVLSVVA Q+ SIQ AI K + F F G E+SLNP+ +FITMNPGYAGR ELP+
Sbjct: 1484 NRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSLNPTCAVFITMNPGYAGRAELPD 1543
Query: 1985 NLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGL 2044
NLK+LFR AM+VPD+ LI EI L + GF++++SLA+K + Y+LC E LS Q HYD+G+
Sbjct: 1544 NLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQKIVATYRLCSEQLSSQHHYDYGM 1603
Query: 2045 RAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDVP 2104
RA+KSVL AG+LK P+ E +L+R+L D N+ K + D+P+F G+I DLFP + +P
Sbjct: 1604 RAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKFLAQDVPLFQGIISDLFPGVVLP 1663
Query: 2105 RRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQ----- 2159
+ F ++ I +KLQ F+ K++Q+ E++ VRH +VG GK+
Sbjct: 1664 KPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMMLVRHGYMIVGDPMGGKTSAYKVL 1723
Query: 2160 --VLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANIT 2217
L LH Q+ + + +NPKA+T +L+G + + EW DG+ ++ RE A+
Sbjct: 1724 AAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFDQVSHEWMDGVLANAFREQASSL 1783
Query: 2218 HDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPA 2277
D KWI+ DG +D +WIE++NTV+DDNK L L S E I +N M L+FE + L A+PA
Sbjct: 1784 SDDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLMSGEIIQMNSKMSLIFEPADLEQASPA 1843
Query: 2278 TVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYL---PTCLDTLRTRFK 2334
TVSR G++Y+ P LGW P S+++ + + ++ D ++ CL+ R K
Sbjct: 1844 TVSRCGMIYMEPHQLGWKPLKDSYMDTLPSSLTKEHKELVNDMFMWLVQPCLEFGRLHCK 1903
Query: 2335 KII---PIP-EQSMVQMVCHLLECLLTTEDIPADCPKEI--------YEHYFVFAAIWAF 2382
++ PI SM+++ LL+ + E+ + + + + F+F+ +W
Sbjct: 1904 FVVQTSPIHLAFSMMRLYSSLLDEIRAVEEEEMELGEGLSSQQIFLWLQGLFLFSLVWTV 1963
Query: 2383 GGAMVQDQLVDYRAEFSKWWL------TEFKTVK------FPSQGTIFD-YYIDPETKKF 2429
G + D + F + K+VK FP +G+I+D Y+I + +
Sbjct: 1964 AGTINADSRKKFDVFFRNLIMGMDDNHPRPKSVKLTKNNIFPERGSIYDFYFIKQASGHW 2023
Query: 2430 EPWSKLVPQFEFDPEMPLQA----CLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKS 2485
E W++ + + E ++P A ++ T ET R +F++ + + P++ VG GTGKS
Sbjct: 2024 ETWTQYITKEE--EKVPAGAKVSELIIPTMETARQSFFLKTYLDHEIPMLFVGPTGTGKS 2081
Query: 2486 VLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFID 2545
+ L L YL + F+ T++ Q ++ L+++ +GPP KK + F+D
Sbjct: 2082 AITNNFLLHLPKNTYLPNCINFSARTSANQTQDIIMSKLDRRRKGLFGPPIGKKAVVFVD 2141
Query: 2546 DMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFT-INP 2604
D+NMP + YG P ++RQ +D+G+W+D+ + +I ++ V+ M P G I
Sbjct: 2142 DLNMPAKEVYGAQPPIELLRQWIDHGYWFDKKDTTRLDIVDMLLVTAMGPPGGGRNDITG 2201
Query: 2605 RLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIAT 2664
R RH ++ ++ D L+ I+S I+ H G F + L+ ++
Sbjct: 2202 RFTRHLNIISINAFEDDILTKIFSSIVDWHFGKG-FDVMFLRYGKMLVQATKTIYRDAVE 2260
Query: 2665 TFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKD 2724
FLPT K HY+FNLRDF+ + QG+L ++ IRL++HE RV+ D++++++D
Sbjct: 2261 NFLPTPSKSHYVFNLRDFSRVIQGVLLCPHTHLQDVEKCIRLWIHEVYRVFYDRLIDKED 2320
Query: 2725 ----FDLFDKIQTEVLKKTFDDI---EDPVEQTQSPNLYCHFANGIGEPK-----YMPVQ 2772
F++ + + K+T + + P + N+ F +P+ Y +
Sbjct: 2321 RQVFFNMVKETTSNCFKQTIEKVLIHLSPTGKIVDDNIRSLFFGDYFKPESDQKIYDEIT 2380
Query: 2773 SWELLTQTLVEALENHNEVNTV-MDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGK 2831
+ LT + LE N ++ M LV+F A+ H+ I R+L+ +G+ LLVG+GGSG+
Sbjct: 2381 DLKQLTVVMEHYLEEFNNISKAPMSLVMFRFAIEHISRICRVLKQDKGHLLLVGIGGSGR 2440
Query: 2832 QSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADER 2891
QS +L+ F+++ +++QI + K Y D++ DL + L+ GV +TVFL D Q+ DE
Sbjct: 2441 QSAAKLSTFMNAYELYQIEITKNYAGNDWREDLKKIILQVGVATKSTVFLFADNQIKDES 2500
Query: 2892 FLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQG--LVDNRENCWKFFIDRIRRQL 2949
F+ IN LL +G++P+++ DE +I+ ++ ++QG + + + FFI+R+ ++
Sbjct: 2501 FVEDINMLLNTGDVPNIFPADEKADIVEKMQTAARTQGEKVEVTPLSMYNFFIERVINKI 2560
Query: 2950 KVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQ 3009
+L SP+G+ R R R FP+++NC I WF WP ALE V+ +FL++ E ++ ++
Sbjct: 2561 SFSLAMSPIGDAFRNRLRMFPSLINCCTIDWFQSWPTDALELVANKFLEDVE-LDDNIRV 2619
Query: 3010 SISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERL 3069
+ + SV + S Y + +R+NY TP S+LE I +++LL+ R+E+ R
Sbjct: 2620 EVVSMCKYFQESVKKLSLDYYNKLRRHNYVTPTSYLELILTFKTLLNSKRQEVAMMRNRY 2679
Query: 3070 ENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEE 3129
GL KL ++QV ++ +L A + +L +E+ K++ + ET + +K + +E
Sbjct: 2680 LTGLQKLDFAASQVAVMQRELTALQPQLILTSEETAKMMVKIEAETREADGKKLLVQADE 2739
Query: 3130 QKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVS 3189
++ V + + +CE DLA+A PAL AA AAL+TLN +++ +KS +PP V V
Sbjct: 2740 KEANVAAAIAQGIKNECEGDLAEAMPALEAALAALDTLNPADISLVKSMQNPPGPVKLVM 2799
Query: 3190 AAVMVLMAPRGRVPKDRS---------WKAAKVTMAKVDGFLDSLINFNKENIHENCLKA 3240
++ ++ + D S W +K + + FL+SL ++K+NI +K
Sbjct: 2800 ESICIMKGMKPERKPDPSGSGKMIEDYWGVSKKILGDLK-FLESLKTYDKDNIPPLTMKR 2858
Query: 3241 IRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAA 3299
IR ++ PEF P + S A GLC WV + + V V PKR+ L +A L A
Sbjct: 2859 IRERFINHPEFQPAVIKNVSSACEGLCKWVRAMEVYDRVAKVVAPKRERLREAEGKLAAQ 2918
Query: 3300 QEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASEN 3359
+KL +A++ + + L L FE+ K ++ E+ + + A +L+ GL E
Sbjct: 2919 MQKLNQKRAELKLVVDRLQALNDDFEEMNTKKKDLEENIEICSQKLVRAEKLISGLGGEK 2978
Query: 3360 VRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTP-IP 3418
RW +A + + L GD+LL + ++YLG FT YR ++ +L++ K IP
Sbjct: 2979 DRWTEAARQLGIRYTNLTGDVLLSSGTVAYLGAFTVDYRVQCQNQ----WLAECKDKVIP 3034
Query: 3419 VTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKN 3478
L D + AWQ GLP D S++N I+ N RW LM+DP Q KWIKN
Sbjct: 3035 GFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSIDNGIIVSNSRRWALMIDPHGQANKWIKN 3094
Query: 3479 -KYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RF 3535
+ L V + Y++++E AL+ G VLIEN+ E +D + P+L + K+ +
Sbjct: 3095 MEKANKLAVIKFSDSNYMRMLENALQLGTPVLIENIGEELDASIEPILLKATFKQQGVEY 3154
Query: 3536 IKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMER 3595
+++G+ EY+ F+L + T+L NPHY PE+ + L+NF +T GL+DQLL V + E+
Sbjct: 3155 MRLGENIIEYSRDFKLYITTRLRNPHYLPEVAVKVCLLNFMITPLGLQDQLLGIVAAKEK 3214
Query: 3596 PDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVE 3655
P+LE+ K+ L + K LK +ED +L LS + GN L + ++ L +K + E+
Sbjct: 3215 PELEEKKNQLIVESAKNKKHLKEIEDKILEVLSMSKGNILEDETAIKVLSSSKVLSEEIS 3274
Query: 3656 KKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVE 3715
+K + A +TE +I+E R Y+P A ++ ++F ++DL+ I PMYQ+SL F ++ ++
Sbjct: 3275 EKQKVASMTETQIDETRMGYKPVAVHSATIFFCISDLANIEPMYQYSLTWFINLYMHSLT 3334
Query: 3716 RAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELD 3775
+ E L R+ +ID T S+Y R LFE DKL + LT I+ +E+
Sbjct: 3335 HSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFEKDKLLFSLLLTIGIMKQKKEITEEVWY 3394
Query: 3776 FLLRSPVQTGTASP---VEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESEC 3832
FLL + P ++LS +AW + S++ + L +E + WK +S
Sbjct: 3395 FLLTGGIALDNPYPNPAPQWLSEKAWAEIVRASALPKLHGLMEHLEQNLGEWKLIYDSAW 3454
Query: 3833 PEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEE 3892
P +E+LP WK L+++ +LR +RPD+M A+R+F+ E +G Y+ D S+ +
Sbjct: 3455 PHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPAVREFIAEHMGKLYIEAPTFDLQGSYND 3514
Query: 3893 SGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKK 3952
S P+ F+LSP DP+ + LG +SLGQGQ +A ++ A K
Sbjct: 3515 SSCCAPLIFVLSPSADPMAGLLKFADDLG--MGGTRTQTISLGQGQGPIAAKMINNAIKD 3572
Query: 3953 GHWVILQNIHLVAKWLSTLEKKLEE--HSENSHPEFRVFMSAEPAPSPEGHIIPQGILEN 4010
G WV+LQN HL A W+ TLEK EE E+++ FR+++++ P+ P IL+N
Sbjct: 3573 GTWVVLQNCHLAASWMPTLEKICEEVIVPESTNARFRLWLTSYPSEK-----FPVSILQN 3627
Query: 4011 SIKITNEPPTGMHANLHKA-LDNFTQDTL--EMCSRETEFKSILFALCYFHAVVAERRKF 4067
IK+TNEPP G+ ANL ++ L++ D + + C++ ++ +LF LC+FHAVV ERR F
Sbjct: 3628 GIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCAKAVMWQKMLFGLCFFHAVVQERRNF 3687
Query: 4068 GPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLC 4127
GP GWN Y FN DL IS+ + FL +VP+D L YL GE YGG +TDD DRRL
Sbjct: 3688 GPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPFDALTYLTGECNYGGRVTDDKDRRLL 3747
Query: 4128 RTYLGEFIRPEMLEGELSLAPG--FPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEI 4185
+ L F E+ E SLAPG + +P + Y Y Y+ P ++GLH NA+I
Sbjct: 3748 LSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQSYIDYLRNLPITAHPEVFGLHENADI 3807
Query: 4186 GFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMA-- 4243
Q + +LF VL PR S G+G + +E V+ L ++IL ++ +F++ E+M
Sbjct: 3808 TKDNQETNQLFEGVLLTLPRQS---GGSGKSPQEVVEELAQDILSKLPRDFDLEEVMKLY 3864
Query: 4244 KVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVP 4303
V V QE R N LT+ ++RSL L +KG++ M+S +E + N++ VP
Sbjct: 3865 PVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGRAIKGQVLMSSELEEVFNSMLVGKVP 3924
Query: 4304 ESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQST 4363
WA ++YPS L + DLL R+ + W D P W++GF+ QSFLT + Q+
Sbjct: 3925 AMWAAKSYPSLKPLGGYVADLLARLTFFQEWI-DKGPPVVFWISGFYFTQSFLTGVSQNY 3983
Query: 4364 ARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDL 4423
ARK P+D + + ++T + + P +GAYI GLF+EGA WD + I E+ K L
Sbjct: 3984 ARKYTIPIDHIGFEFEVTPQ-ETVMENNPEDGAYIKGLFLEGARWDRKTMQIGESLPKIL 4042
Query: 4424 TPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTKENPSK 4474
P+P++++K + + +Y CPVYKTS R T YV + L T
Sbjct: 4043 YDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRGTLSTTGHSTNYVLSIELPTDMPQKH 4102
Query: 4475 WVLAGVALLLQI 4486
W+ GVA L Q+
Sbjct: 4103 WINRGVASLCQL 4114
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 1920 bits (4974), Expect = 0.0
Identities = 1191/3668 (32%), Positives = 1940/3668 (52%), Gaps = 141/3668 (3%)
Query: 913 KAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGS 972
K PIF A ++LAIP +V P+LE V+ VE +I+ +P V + S + S
Sbjct: 1003 KQNSLPIFRASVTLAIPNIVMAPALED-VQQTLNKAVECIIS----VPKGVRQWSSELLS 1057
Query: 973 PH---------YQVDLDGIPDLANMRRTLMERVQ-RMMGLCCGYQST------------- 1009
Q + D D+ L + ++ + L Q+
Sbjct: 1058 KKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYKNVSENKEIV 1117
Query: 1010 --FSQYSYLYVEDRKEVLGQ---FLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDS 1064
S S + +KEV+ F Y HI + E+ ++ I ++P LLS+F+ QI
Sbjct: 1118 KLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGK-EEAIKTFITQSP-LLSEFESQILY 1175
Query: 1065 YETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDA 1124
++ L +E+ EP V G + + K +L K W ++ +H + N+
Sbjct: 1176 FQNLEQEI-NAEPEYVCVGSIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFM 1234
Query: 1125 FIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELP 1184
I++ L + ++ D + M L ++E Q + D P++++ LL Y +
Sbjct: 1235 LIEEFNKKLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIA 1292
Query: 1185 ETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKE 1244
+++ L W + A V+ ++ LQ + L F + QF+ +
Sbjct: 1293 REEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLN 1352
Query: 1245 APFRFDSIHPHQMLDARHIEIQQMESTMA---SISESASLFEVNVPDYKQLRQCRKEVCQ 1301
P + P + D + Q ++ + + LF + Y QL + +K++
Sbjct: 1353 GPMA-SGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNL 1411
Query: 1302 LKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLES 1361
L++++ V +++++ W +N+E + E +F R L + ++ W AF L+
Sbjct: 1412 LQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKK 1471
Query: 1362 TVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDT-TLAHLLQLQLHHYEDEV 1420
+ + + + + A+ ERHW ++ TG S + ++ L ++++ L Y++E+
Sbjct: 1472 IIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEI 1531
Query: 1421 RGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDE--DLIEVLEDNQVQ 1478
I A KE +E+ LK++ W F + LL D ++I +ED+ +
Sbjct: 1532 EDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLML 1591
Query: 1479 LQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQ 1538
L +L+ ++Y F ++ W + LS +I W VQ W +LE++F G DI QLP+
Sbjct: 1592 LGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGG-DIAKQLPK 1650
Query: 1539 DSKRFEGIDIDFKELAYDAQKIPNVVQT-TNKPGLYEKLEDIQGRLCLCEKALAEYLDTK 1597
++KRF ID + ++ A ++P+VVQ L + L + +L +C+K+L YL+ K
Sbjct: 1651 EAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKK 1710
Query: 1598 RLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMY 1657
RL FPRF+F+S LL+IL + +Q HL +FDN+ ++F L +
Sbjct: 1711 RLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDR----ILSIS 1766
Query: 1658 SKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPRE--QWLFDHP 1715
S+E E + +P G VE+WLN +L ++++ + + +E + ++L P
Sbjct: 1767 SQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFP 1826
Query: 1716 AQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQK 1775
AQV L Q+ WT + A R + + M+ + + L TLI + LS +R K
Sbjct: 1827 AQVGLLGIQMIWTRDSEEAL-RNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVK 1885
Query: 1776 IMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYE 1835
T+ TI VH RD+ + + + F WL Q R ++++ +I D F+Y E
Sbjct: 1886 YETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNE 1945
Query: 1836 YLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFN 1895
+LG T RLVITPLTDRCYITL Q+L ++M GAPAGPAGTGKTETTKD+GR LG V VFN
Sbjct: 1946 FLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFN 2005
Query: 1896 CSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSF 1955
CS+QMD++ G I+KGLAQ+G+WGCFDEFNRI + VLSV A Q+ I ++ K+ F F
Sbjct: 2006 CSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIF 2065
Query: 1956 L-GEEISLNPSVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFI 2014
G+ +++NP G+F+TMNPGYAGR ELPENLK FR AM+VPD ++I + L + GFI
Sbjct: 2066 TDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFI 2125
Query: 2015 EAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSL 2074
+ LARKF TLY+LC+E LSKQ HYD+GLR I SVL G+ KR +P E ++MR L
Sbjct: 2126 DNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVL 2185
Query: 2075 RDFNIPKIVTDDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKV 2134
RD N+ K++ +D P+F+ LI DLFP + + + P EA + + + + L + LKV
Sbjct: 2186 RDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKV 2245
Query: 2135 VQLEELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGII 2194
+QL E VRH + +G +G GK+ + +L + + +NPKA+T ++FG +
Sbjct: 2246 IQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRL 2305
Query: 2195 NPATGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNE 2254
+ AT +W DG+FS++ R+ WI+LDG +D +WIE+LN+V+DDNK LTLA+ +
Sbjct: 2306 DVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGD 2365
Query: 2255 RIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKR---EIQTER 2311
RIP+ P K++FE ++ A+PATVSR G+++++ + L W+P + +++KR E + R
Sbjct: 2366 RIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILR 2425
Query: 2312 ANLTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYE 2371
T F C+ L + + + E ++ ++L+ L+ ++ + +
Sbjct: 2426 QLYTESFPDLYRFCIQNLEYKME----VLEAFVITQSINMLQGLIPLKEQGGEVSQAHLG 2481
Query: 2372 HYFVFAAIWAFGGAMVQDQLVDYRAEFSKWWLTE-FKTVKFPSQG----TIFDYYIDPET 2426
FVFA +W+ G A+ +D R W + T++ P T FDYY+ P+
Sbjct: 2482 RLFVFALLWSAGAALE----LDGRRRLELWLRSRPTGTLELPPPAGPGDTAFDYYVAPD- 2536
Query: 2427 KKFEPWSKLVPQFEF--DPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGK 2484
+ W+ ++ + D + LV + +R + ++ + + + V+L+G GT K
Sbjct: 2537 GTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAK 2596
Query: 2485 SVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFI 2544
+V++ ++ DPE +++K++ F+ TT M Q +E ++K+ G YGPP KK+ FI
Sbjct: 2597 TVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFI 2656
Query: 2545 DDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKL-SLKEITNVQYVSCM-NPTAGSFTI 2602
DD+NMP ++ +G + I+RQ ++ +Y+ K I ++Q+++ M +P G I
Sbjct: 2657 DDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDI 2716
Query: 2603 NPRLQRHFSVFVLSFPGADALSSIYSIILTQH-LKLGNFPASLQKSIPPLIDLALAFHQK 2661
RL+R FS+F + P ++ I+ +I H F ++ S+ L+ L Q
Sbjct: 2717 PQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQM 2776
Query: 2662 IATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVE 2721
LPT KFHY+FNLRD + ++QG+L ++ E +K DL++L+ HE RV D+
Sbjct: 2777 TKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTV 2836
Query: 2722 EKDFDLFDKIQTEVLKKTFDDIEDPVEQTQSPNLYCHFANGIGE-------------PK- 2767
D FDK ++++ F + + + + F E PK
Sbjct: 2837 SSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKI 2896
Query: 2768 YMPVQSWELLTQTLVEALENHNEV--NTVMDLVLFEDAMRHVCHINRILESPRGNALLVG 2825
Y P++S+ L + L L+ +NE MD+V F DAM H+ I+R++ +P+GNALLVG
Sbjct: 2897 YEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVG 2956
Query: 2826 VGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDA 2885
VGGSGKQSLTRLA+FI+ FQITL + Y + DL L AG + F+ TD
Sbjct: 2957 VGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDN 3016
Query: 2886 QVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQ--GLVDNRENCWKFFID 2943
++ DE FL +N++L+SGE+ +L++ DE++ I S++ + +K + + EN +F+
Sbjct: 3017 EIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMS 3076
Query: 2944 RIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTE-G 3002
R+R+ L + LCFSPVG K R R+ KFPA+++ I WF WP+ AL +VS FL + +
Sbjct: 3077 RVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDID 3136
Query: 3003 IEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKEL 3062
+K+ + + M V + Y +R + TPKS+L FI+ Y+ + E+
Sbjct: 3137 CSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEV 3196
Query: 3063 KCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREK 3122
+ R+ GL KL S V L +L A+E EL+ N+ AD +++ V ++ + K
Sbjct: 3197 RTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVK 3256
Query: 3123 AMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPP 3182
A + + + I+ + + + EE L A+PAL A+AAL T+ +++ +++ G PP
Sbjct: 3257 AEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPP 3316
Query: 3183 LAVSNVSAAVMVLMAPRGRVPK--------DRSWKAAKVTMAKVDGFLDSLINFNKENIH 3234
+ + V++L + K SW+ + + + FL +L F K+ I+
Sbjct: 3317 HLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQES-LKLMTAGNFLQNLQQFPKDTIN 3375
Query: 3235 ENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATA 3294
E ++ + PY + P++N E AGLCSW + F+ + +V P + L
Sbjct: 3376 EEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQEN 3435
Query: 3295 DLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTISLANRLVGG 3354
A + L +A++ L + A +E+A +K ++AE + A+ L+ G
Sbjct: 3436 RHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISG 3495
Query: 3355 LASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLK 3414
LA E RW + Q F Q + L GD+LL TAF+SY G F +++R LL+ WR + K
Sbjct: 3496 LAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLN-DWRKEMKARK 3554
Query: 3415 TPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMVDPQLQGIK 3474
IP L+ ML+D ++ W +GLP D +S++N I+ R+PL++DPQ QG
Sbjct: 3555 --IPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKI 3612
Query: 3475 WIKNKYG-EDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG 3533
WIKNK +L++T + K + +E +L G +LIE++ E +DP L +L R IK G
Sbjct: 3613 WIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTG 3672
Query: 3534 RF--IKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVV 3591
+K+GDKE + FRL + TKL NP Y PE+ A+ ++I+FTVT GLEDQLL V+
Sbjct: 3673 STFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVI 3732
Query: 3592 SMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTA 3651
E+ +LE+ ++ L + K +K LED+LL RL+S G+ + + L+ L TK+TA
Sbjct: 3733 LTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTA 3792
Query: 3652 AEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQ 3711
EV +K++ + TEV+IN ARE YRP A R S+LYF++ ++ ++ MYQ SL+ F +F
Sbjct: 3793 EEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFD 3852
Query: 3712 KAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNA 3771
++ R+ +R+AN+I+ +T+ VY+Y RGL+E K + LT +I + V
Sbjct: 3853 LSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKH 3912
Query: 3772 VELDFLLRS----PVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKF 3827
E L++ ++ P +++ W + LS + +FS++ I + K WK +
Sbjct: 3913 EEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIW 3972
Query: 3828 VESECPEKEKLPQEW-KNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDF 3886
+ E PE+E LP + K+ +RL ++R+ PDR R ++ + +G KY G LD
Sbjct: 3973 FDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDL 4032
Query: 3887 ATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAAL 3946
++EES P TP+ +LS G DP + + G++L VS+GQGQEV A L
Sbjct: 4033 EKTWEESDPRTPLICLLSMGSDPTDSIIALGKRL-----KIETRYVSMGQGQEVHARKLL 4087
Query: 3947 DLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQG 4006
G W +LQN HL ++ L + E +E H FR++M+ E P
Sbjct: 4088 QQTMANGGWALLQNCHLGLDFMDELMDIIIE-TELVHDAFRLWMTTEAHKQ-----FPIT 4141
Query: 4007 ILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRK 4066
+L+ SIK N+PP G+ A L + +QD L++ S +++K +L+A+ + H+ V ERRK
Sbjct: 4142 LLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDV-SSGSQWKPMLYAVAFLHSTVQERRK 4200
Query: 4067 FGPQGWNRSYPFNTGDLTISVNVLYNFL---EANAKVPYDDLRYLFGEIMYGGHITDDWD 4123
FG GWN Y FN D +V + N L + V + +RY+ GEI YGG +TDD+D
Sbjct: 4201 FGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYD 4260
Query: 4124 RRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNA 4183
+RL T+ + M + S G+ +P + Y QYI + +SP ++GLHPNA
Sbjct: 4261 KRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNA 4320
Query: 4184 EIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDE---FNIPE 4240
+I + ++ ++ + T+L +QP+D+ G TRE V L +++LE++ + F + E
Sbjct: 4321 DITYQSKLAKDVLDTILGIQPKDTSG--GGDETREAVVARLADDMLEKLPPDYVPFEVKE 4378
Query: 4241 LMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFD 4300
+ K+ P + QE RM + ++ +L EL+L + G + M+ ++ + + ++
Sbjct: 4379 RLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDA 4438
Query: 4301 MVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIM 4360
+P W + ++ S+ L WF +L+ R + +W + P W+TGFFNPQ FLTA+
Sbjct: 4439 RIPAWWKKASWISST-LGFWFTELIERNSQFTSWVFN-GRPHCFWMTGFFNPQGFLTAMR 4496
Query: 4361 QSTARKNE-WPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAK 4419
Q R N+ W LD M L ++TK +++ +PP EG Y++GL++EGA WD + + E+K
Sbjct: 4497 QEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESK 4556
Query: 4420 LKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGP-TYVWTFNLKTKENPSKWVLA 4478
K L MPV+ I A +D R YSCP+YK R Y+ +L+T + P WVL
Sbjct: 4557 PKVLFELMPVIRIYAENNTLRDPR-FYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLR 4615
Query: 4479 GVALLLQI 4486
GVALL +
Sbjct: 4616 GVALLCDV 4623
Score = 183 bits (465), Expect = 3e-45
Identities = 169/746 (22%), Positives = 318/746 (42%), Gaps = 61/746 (8%)
Query: 90 GPESGLAGAKALFFLRTGPEPP-GPDSFRGAVVCGDLPAAP---LEHLAALFSEVVLPVL 145
G + L G +FF+RT P PD+ V L AA L + L S++ +P L
Sbjct: 118 GNDVALTGV-CVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPAL 176
Query: 146 A------NEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFAD 199
E L I ++ LS E +K K L + +E
Sbjct: 177 RATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNL---RKCDILELKT 233
Query: 200 SKSETVLDSI--DKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKS 257
K T ++ + + IE + W Q + VL E++Q L + ++ P+ ELE WK
Sbjct: 234 LKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLA-ENNQLLKEADDVGPRAELEHWKK 292
Query: 258 RYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQ 317
R Y+ QL++ V+ + +L +S ++ M + A EA+D +L L+
Sbjct: 293 RLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLE 352
Query: 318 RHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYL 377
+ + L +++ + + L++ + +I++ Y + ++T L ++ N +I Y+
Sbjct: 353 KCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYI 412
Query: 378 S----------PEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKE 427
+ P+D++ ++ + + KQE+Q K+N K+
Sbjct: 413 TNNGTASIWNQPQDVVEEKILSAIK-----------LKQEYQLCFHKTKQKLKQNPNAKQ 461
Query: 428 WDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQ 487
+DF +F + + F +L + + T + L G ++ M ++Q
Sbjct: 462 FDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEG---------LEDMATKYQ 512
Query: 488 EMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLL 547
+ + + L + DF+ D EF ++ DL L F A ++L
Sbjct: 513 GIVATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRML 572
Query: 548 DIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNMPTV 607
L P + D DKY ++++ + D+D + +Y++ + P+ +N P +
Sbjct: 573 K-KFERLNIPNLGID--DKYQLILENYGADIDMISKLYTKQKYD------PPLARNQPPI 623
Query: 608 AGGLRWAQELRQRIQGPFSNFGRITHPC-MESAEGKRMQQKYEDMLSLLEKYETRLYEDW 666
AG + WA++L RIQ P F + HP + +AE K + + Y M +L ++E + W
Sbjct: 624 AGKILWARQLFHRIQQPMQLFQQ--HPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAW 681
Query: 667 CRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMF 726
R + E+ L LL + P T E+ +NF+PQ++ + +E + ++ P A ++F
Sbjct: 682 LRQI-EEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSP-LATSLF 739
Query: 727 SSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGI 786
RD Y++ +N+++M Y +V + L+ L +D L+ L W + I
Sbjct: 740 QKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNI 799
Query: 787 CDYVTEITSSIHDLEQRIQKTKDNVE 812
Y+ + I DLE + + D +E
Sbjct: 800 EAYLENTFAKIKDLELLLDRVNDLIE 825
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 1624 bits (4205), Expect = 0.0
Identities = 798/798 (100%), Positives = 798/798 (100%)
Query: 3689 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 3748
MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3749 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSME 3808
CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSME
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSME 120
Query: 3809 EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRD 3868
EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRD
Sbjct: 121 EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRD 180
Query: 3869 FVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQN 3928
FVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQN
Sbjct: 181 FVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQN 240
Query: 3929 FHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRV 3988
FHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRV
Sbjct: 241 FHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRV 300
Query: 3989 FMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFK 4048
FMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFK
Sbjct: 301 FMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFK 360
Query: 4049 SILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYL 4108
SILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYL
Sbjct: 361 SILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYL 420
Query: 4109 FGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAE 4168
FGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAE
Sbjct: 421 FGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAE 480
Query: 4169 LPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEI 4228
LPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEI
Sbjct: 481 LPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEI 540
Query: 4229 LERVTDEFNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTS 4288
LERVTDEFNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTS
Sbjct: 541 LERVTDEFNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTS 600
Query: 4289 HMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTG 4348
HMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTG
Sbjct: 601 HMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTG 660
Query: 4349 FFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACW 4408
FFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACW
Sbjct: 661 FFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACW 720
Query: 4409 DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKT 4468
DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKT
Sbjct: 721 DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKT 780
Query: 4469 KENPSKWVLAGVALLLQI 4486
KENPSKWVLAGVALLLQI
Sbjct: 781 KENPSKWVLAGVALLLQI 798
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1408 bits (3645), Expect = 0.0
Identities = 998/3568 (27%), Positives = 1743/3568 (48%), Gaps = 280/3568 (7%)
Query: 1126 IKKSESGLLK-KVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELP 1184
I KS L + V+ V + ++ ++K + ++ E + LL+ + P
Sbjct: 1146 ISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFP 1205
Query: 1185 ETVFKQLEELPEKW---NNI-KKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQ 1240
+ + ++ + +W N+I ++ ++QQVA LQ V Q A ++
Sbjct: 1206 PS-WLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIV----QEDRAVESRTTDLLTD 1260
Query: 1241 FHKEAPFRFDSIHPHQMLDARHI------EIQQMESTMASISESASLFEVNV--PDYKQL 1292
+ K P ++ P + L A I ++ A E+ L + + +++
Sbjct: 1261 WEKTKPVT-GNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERV 1319
Query: 1293 RQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRA 1352
+ +E+ LK +W + V I + PW ++ + +++ +R
Sbjct: 1320 QVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQ 1379
Query: 1353 WDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQ 1412
+ ++ ++ + + V EL++ A+++RHW+QLM+ V++ + + TL + +
Sbjct: 1380 YASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSE-LTLGQIWDVD 1438
Query: 1413 LHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVL 1472
L E V+ ++ A EM +E+ LK+++ W E + + L+ +DL +
Sbjct: 1439 LQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNY-QNKCRLIRGWDDLFNKV 1497
Query: 1473 EDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDI 1532
+++ + + +S Y F E+ W+ KL+ + A+ +W +VQR W +LE IFTGS DI
Sbjct: 1498 KEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADI 1557
Query: 1533 RAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAE 1592
+ LP +++RF+ I +F L K P V+ N G+ LE + L +KAL E
Sbjct: 1558 KHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGE 1617
Query: 1593 YLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKT 1652
YL+ +R +FPRFYF+ DLL+I+ N ++Q+H K+F ++ + D S
Sbjct: 1618 YLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNS-----V 1672
Query: 1653 SLGMYSKEEEYVAFSEPCDCSGQVEI--WLNHVLGHMKATVRHEMTEGVTAYEEKPREQ- 1709
LG+ S+E E V F P + +I WL V M+ T+ + E VT E +
Sbjct: 1673 VLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATS 1732
Query: 1710 --------WLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESA-MKDYYKKQVAQLKTL 1760
W+ + AQ+ + QI W+ V A + + G ++A + L L
Sbjct: 1733 IDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVL 1792
Query: 1761 ITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWD----D 1816
++ + R+K+ + T VH RDV +I K+DNA++F WLSQ+R +D D
Sbjct: 1793 ADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTD 1852
Query: 1817 EVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGK 1876
++ + +A+F Y +EYLG +LV TPLTDRCY+T+TQ+L + G+P GPAGTGK
Sbjct: 1853 VLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGK 1912
Query: 1877 TETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVA 1936
TE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +LS V+
Sbjct: 1913 TESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVS 1972
Query: 1937 VQVKSIQDAIRDKKQ----------WFSFLGEEISLNPSVGIFITMNPGYAGRTELPENL 1986
QV+ IQ+A+R+ L +++ ++P + IFITMNPGYAGR+ LP+NL
Sbjct: 1973 QQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNL 2032
Query: 1987 KSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRA 2046
K LFR AM PD +LI ++ML ++GF A+ LA K + ++LC E LS Q HYD+GLRA
Sbjct: 2033 KKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRA 2092
Query: 2047 IKSVLVVAGSLKRGDPDR---------------------PEDQVLMRSLRDFNIPKIVTD 2085
+KSVLV AG++KR + PE ++L++S+ + +PK+V +
Sbjct: 2093 LKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAE 2152
Query: 2086 DMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDN------FVLKVVQLEE 2139
D+P+ L+ D+FP + R ++K ++ L D +V KV+QL +
Sbjct: 2153 DIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQ 2212
Query: 2140 LLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKR-RPVWTDLNPKAVTNDELFGIINPAT 2198
+ + H + +VG +G+GKS R L K + ++ V ++PKA++ D L+G ++P T
Sbjct: 2213 ITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNT 2272
Query: 2199 GEWKDGLFSSIMRELANITH---DGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNER 2255
EW DGLF+ ++R++ + +WI+ DGD+DP W+E+LN+V+DDNK+LTL + ER
Sbjct: 2273 REWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGER 2332
Query: 2256 IPLNPTMKLLFEISHLRTATPATVSRAGILYIN--------------------PADLGWN 2295
+ L P ++++FE+ L+ AT ATVSR G+++ + P D G +
Sbjct: 2333 LSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGED 2392
Query: 2296 PPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPIPEQ------------- 2342
K + E A+ + + T + T + E
Sbjct: 2393 EAQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRL 2452
Query: 2343 -------SMVQMVC-HLLECLLTTEDIPADCPK--EIYEHYFVFAAIWAFGGAMVQDQLV 2392
SM+ C ++ + D P + + Y V+A +W+ G D +
Sbjct: 2453 RCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG----DSRL 2508
Query: 2393 DYRAEFSKWWLTEFKTVKFPSQGTI--FDYYIDPETKKFEPWSKLVPQFEFDP-EMPLQA 2449
RAE ++ + TV P+ I DY + + ++ PW VPQ E + ++
Sbjct: 2509 KMRAELGEY-IRRITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKVAAPD 2566
Query: 2450 CLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNY 2509
+V T +T+R + +A +P++L G G+GK++ + + L +L P+ +V + F+
Sbjct: 2567 VVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRAL-PDMEVV-GLNFSS 2624
Query: 2510 YTTSAMLQAVLEKPLEKKAGRN---YGPPG-NKKLIYFIDDMNMPEVDAYGTVQPHTIIR 2565
TT +L + E + N P K L+ F D++N+P++D YGT + + IR
Sbjct: 2625 ATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIR 2684
Query: 2566 QHLDYGHWYDRSKLSLKEITNVQYVSCMNPTA--GSFTINPRLQRHFSVFVLSFPGADAL 2623
Q +++G +Y S + ++ +Q+V NP G ++ R RH V + +PG +L
Sbjct: 2685 QMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASL 2744
Query: 2624 SSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFA 2683
+ IY L+L SL+ PL + F+ F + HYI++ R+
Sbjct: 2745 TQIYGTFNRAMLRL---IPSLRTYAEPLTAAMVEFYTMSQERFTQD-TQPHYIYSPREMT 2800
Query: 2684 NIFQGILFSSVECVKS--TWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFD 2741
+GI F ++ +++ LIR++ HE+ R+++D++VE+++ D+ V K F
Sbjct: 2801 RWVRGI-FEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFP 2859
Query: 2742 DIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEA-LENHNEVNTVMDLVLF 2800
+I D + P LY ++ + Y+PV EL + V+A L+ E + LVLF
Sbjct: 2860 NI-DREKAMSRPILYSNWLS----KDYIPVDQEEL--RDYVKARLKVFYEEELDVPLVLF 2912
Query: 2801 EDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDF 2860
+ + HV I+RI P+G+ LL+GV G+GK +L+R A+++ + V+QI + + Y +DF
Sbjct: 2913 NEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDF 2972
Query: 2861 KMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISN 2920
DL ++ ++G KN F+M ++ V D FL +N LLA+GE+P L+ DE +++
Sbjct: 2973 DEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQ 3032
Query: 2921 VRNEVKSQGLV-DNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIH 2979
+ + +GL+ D+ E +K+F ++ R L V +P L+ R+ PA+ N ++
Sbjct: 3033 CKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLN 3092
Query: 2980 WFHEWPQQALESVSLRFLQNTEGIEPTV-------------------KQSISKFMAFVHT 3020
WF +W +AL V F + +P +++I FVH
Sbjct: 3093 WFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQ 3152
Query: 3021 SVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTS 3080
+++Q + R TP+ +L+FI Y +L H R EL+ + L GL K+ T
Sbjct: 3153 TLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETV 3212
Query: 3081 AQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 3140
QV++L+ L + EL+ KN A+ ++ + + + ++K M+ E ++++ +
Sbjct: 3213 DQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIA 3272
Query: 3141 QKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRG 3200
KQ +EDL K EPA+ AQ A+ ++ K +L E++S +PP AV ++ +L+
Sbjct: 3273 DKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGE-- 3330
Query: 3201 RVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRP-YLQDPEFNPEFVATKS 3259
WK + + + + F+ +++NF+ E I + + ++ Y+ +P +N E V S
Sbjct: 3331 ---STTDWKQIRSIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRAS 3386
Query: 3260 YAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAK 3319
A + W I + + ++ VEP R L K D Q+K ++ I L ++A+
Sbjct: 3387 LACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIAR 3446
Query: 3320 LTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGD 3379
+ ++ + + ++ + L+ L++E RW + FK Q T+ GD
Sbjct: 3447 YKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGD 3506
Query: 3380 ILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQ 3439
LL AFI+Y G+F ++ RQ+L TW +L Q I + L + + WQ
Sbjct: 3507 CLLSAAFIAYAGYFDQQMRQNLFT-TWSHHLQQAN--IQFRTDIARTEYLSNADERLRWQ 3563
Query: 3440 NEGLPADRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIG--QKGYLQI 3497
LPAD + ENA +L R+PL++DP Q ++I N+Y +D ++T+ + +
Sbjct: 3564 ASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEY-KDRKITRTSFLDDAFRKN 3622
Query: 3498 IEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKGR--FIKIGDKECEYNPKFRLILHT 3555
+E AL G +L++++E S DPVL P+L REV + G I +GD++ + +P F + L T
Sbjct: 3623 LESALRFGNPLLVQDVE-SYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLST 3681
Query: 3556 KLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKIT 3615
+ + P+L ++ T +NFTVTR L+ Q L V+ ERPD+++ +SDL K Q F++
Sbjct: 3682 RDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLR 3741
Query: 3616 LKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHY 3675
L+ LE SLL L+ G L + ++ LE K+ AAEV +KV+E + ++ + Y
Sbjct: 3742 LRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQY 3801
Query: 3676 RPAAARASLLYFIMNDLSKIHPMYQFSLKAF-----SIVFQKAVERAAPDESLRERVANL 3730
P + S +YF M L +IH +YQ+SL+ F +++++ + D + +R++ +
Sbjct: 3802 LPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHT--QRLSII 3859
Query: 3731 IDSITFSVYQYTIRGLFECDKLTYLAQLTFQILL---MNREVNAVELDFLLRS---PVQT 3784
+ + RG+ D +T+ A L +I L + E LR +
Sbjct: 3860 TKDLFQVAFNRVARGMLHQDHITF-AMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSA 3918
Query: 3785 GTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKN 3844
G+ ++ L+ + AV LS + F +L ++ + + +++S PE + +P W
Sbjct: 3919 GSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSSPE-QTVPYLWSE 3976
Query: 3845 KT-------ALQRLCMLRAMRPDRMTYALRDFVEEKLGSKY--VVGRALDFATSF-EESG 3894
+T A+ RL +++A RPDR+ FV LG + ++ + LD E
Sbjct: 3977 ETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVK 4036
Query: 3895 PATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEV-VAEAALDLAAKKG 3953
P TP+ PG D VE + N ++++G + A+ A++ A K G
Sbjct: 4037 PNTPVLMCSVPGYDASGHVEDLAAE-----QNTQITSIAIGSAEGFNQADKAINTAVKSG 4091
Query: 3954 HWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIK 4013
WV+L+N+HL WL LEKKL HS H FR+F++ E P +P +L
Sbjct: 4092 RWVMLKNVHLAPGWLMQLEKKL--HSLQPHACFRLFLTMEINPK-----VPVNLLRAGRI 4144
Query: 4014 ITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWN 4073
EPP G+ AN+ + + +C E + F L +FHA++ ER ++ P GW+
Sbjct: 4145 FVFEPPPGVKANMLRTFSSI--PVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWS 4202
Query: 4074 RSYPFNTGDLTISVNVLYNFLEANA---------KVPYDDLRYLFGEIMYGGHITDDWDR 4124
+ Y F DL + + + +L+ A K+P+ L+ L + +YGG + +++D+
Sbjct: 4203 KKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQ 4262
Query: 4125 RLCRTYLGEFIRPEMLEGELSLA------PGFPLPGNMDYNGYHQYIDAELPPESPYLYG 4178
RL T+L + E LA +P + + Q+++ ++P G
Sbjct: 4263 RLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLG 4322
Query: 4179 LHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVK---------ALLEEIL 4229
L NAE LT + +L++Q + + D A A E+K + A + +
Sbjct: 4323 LPNNAERVLLTTQGVDMISKMLKMQMLEDE-DDLAYAETEKKTRTDSTSDGRPAWMRTLH 4381
Query: 4230 ERVTDEFN-IPELMAKVEE-----RTPYIVVAFQECGRMNILTREIQRSLRELELGLKGE 4283
++ + IP+ ++ ++ + P +E L +++++ L ++ +G+
Sbjct: 4382 TTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGK 4441
Query: 4284 LTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELE------AWTGD 4337
T+++ L N L ++P SW+ P+ + W D RIK+L+ A G
Sbjct: 4442 KKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGA 4501
Query: 4338 FTMPST-VWLTGFFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGA 4396
+ + V L G F P++++TA Q A+ N W L+++ L+ ++T +
Sbjct: 4502 KELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDAC---SF 4558
Query: 4397 YIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQR 4456
+ GL ++GA + ++ A + P + ++K +K+ SV + PVY R
Sbjct: 4559 GVTGLKLQGATCNNNKLSLSNA-ISTALPLTQLRWVKQTNTEKK--ASVVTLPVYLNFTR 4615
Query: 4457 GP-TYVWTFNLKTKENPSKWVLAGVALL 4483
+ F + TKE+P + GVA+L
Sbjct: 4616 ADLIFTVDFEIATKEDPRSFYERGVAVL 4643
Score = 53.5 bits (127), Expect = 5e-06
Identities = 102/635 (16%), Positives = 249/635 (39%), Gaps = 65/635 (10%)
Query: 210 DKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKS------RYEDLK 263
D + + ++S V +W ++Q V K + + T E+ FW + R ++ +
Sbjct: 238 DPTFLNQLQSGVNRWIREIQKVTKLDRDPA-----SGTALQEISFWLNLERALYRIQEKR 292
Query: 264 YIYNQLRTITV----------------RGMAKLLDKLQSSYFPAFKAMYRDVVAALAEAQ 307
L T+ + G+ + L+ + + Y P K + + + E
Sbjct: 293 ESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETV-NDYNPLMKDFPLNDLLSATELD 351
Query: 308 DIHVHLIPLQRHLEALENAEFPE------VKPQLRPLLHVVCLIWATCK----SYRSPGR 357
I L+ + HL + N ++P V+ R L + + T K +Y +
Sbjct: 352 KIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEK 411
Query: 358 LTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHT 417
+ V E+ + Y + LLR V+ + + + ++ ++ Q R + +
Sbjct: 412 VMVACFEVFQTWDDE---YEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRK 468
Query: 418 YFKENQEVKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQ 477
+ +++++++ + +V V +G + D K+ +V F NA+ +
Sbjct: 469 FRRQHEQLR-----AVIVRVLRPQVTAVAQQNQGEVPEPQDM-KVAEVLFDAADANAI-E 521
Query: 478 QVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDA 537
+V +E +E+ L D + +E + ++++++ ++ R+ A
Sbjct: 522 EVNLAYENVKEVDGL------DVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTA 575
Query: 538 PGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGF 597
F++ L RP + + LIQ D++++ + +
Sbjct: 576 KNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKM 635
Query: 598 SPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCMES-AEGKRMQQKYEDMLSLLE 656
S V +++P V+G + WA+++ +++ + E+ EG++++Q + L
Sbjct: 636 SHV-RDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLN 694
Query: 657 KYETRLYEDWCRTVSEKSQ------YNLSQPLLK-RDPETKEITINFNPQLISVLKEMSY 709
E +++DW R V +++ + + ++ R ++ +NF P++I++ KE+
Sbjct: 695 TQE--IFDDWARKVQQRNLGVSGRIFTIESTRVRGRTGNVLKLKVNFLPEIITLSKEVRN 752
Query: 710 LEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNID 769
L+ + + Y ++ +E + + K L+ L+
Sbjct: 753 LKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERNTISLLVAGLKKEV 812
Query: 770 LRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRI 804
L A L W++ + YV + ++ + ++++
Sbjct: 813 QALIAEGIALVWESYKLDPYVQRLAETVFNFQEKV 847
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1251 bits (3238), Expect = 0.0
Identities = 958/3548 (27%), Positives = 1669/3548 (47%), Gaps = 261/3548 (7%)
Query: 1070 EEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKS 1129
+EV RL P V + I+ P K + ++I++ L L + L +D F+ ++
Sbjct: 894 KEVERL-PSAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEA 952
Query: 1130 ESGLLKKVEKGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFK 1189
L + + G + ++ER+ +F+ + LL+T ET+
Sbjct: 953 MEVLTIMPQSVEEIGDANLQ--YSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETI-- 1008
Query: 1190 QLEELPEKWNNIKKVA----ITVKQQVAPLQANEVTLLRQRCTAFDAEQQQF---WEQFH 1242
L KW+ + + + +K Q+ ++ N ++ R + E ++F W+Q
Sbjct: 1009 --SNLKAKWDKFELMMESHQLMIKDQIEVMKGN----VKSRLQIYYQELEKFKARWDQLK 1062
Query: 1243 KEAPFRFDSIH-----PHQMLDARHIEIQQMESTMASISESASLFEVNVPDYKQLRQCRK 1297
H +++ + IE +E T + + F + P++ K
Sbjct: 1063 PGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISK 1122
Query: 1298 EVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFT 1357
++ ++W W + E +F + + ++V T
Sbjct: 1123 DIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFE--EFLMNWHDRLRKVEEHSVMT 1180
Query: 1358 -GLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHY 1416
L+S V + + ++ + HW L + G + + T+L LL L
Sbjct: 1181 VKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLG----LPRGTSLEKLLFGDLLRV 1236
Query: 1417 ED-------EVRGIVDKAAKEMGMEKTLKELQTTWAGMEF---QYEPHPRTNVPLLCSDE 1466
D +++ + +A E+ + + L+EL G F YE + L+ +
Sbjct: 1237 ADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWK 1296
Query: 1467 DLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIF 1526
D++ + DN+ LQ+L S Y F ++VS W++KL+ +D + +QR W +LE IF
Sbjct: 1297 DIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIF 1356
Query: 1527 TGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLC 1586
R LP++ RF +D DF+ + D +K V T G+ L I +L C
Sbjct: 1357 G-----RGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRC 1411
Query: 1587 EKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDAS 1646
+K+L E+L+ KR AFPRFYF+ DLL+IL T P +Q HL KLF + + F
Sbjct: 1412 QKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTNPSVIQSHLKKLFAGINSVCFD---- 1467
Query: 1647 GEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKP 1706
E +K M S E E V F S VE WLN + MK T+ + E VT
Sbjct: 1468 -EKSKHITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQ 1526
Query: 1707 REQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIG 1766
P+Q+ QI +T +V E+A+KD+ + Q++T + +
Sbjct: 1527 GAVDPSLFPSQILCLAEQIKFTEDV-----------ENAIKDH---SLHQIETQLVNKLE 1572
Query: 1767 QLSKGDRQ--------------KIMTICTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRH 1812
Q + D K+ + +H DVV ++ +V + + W QLR
Sbjct: 1573 QYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRF 1632
Query: 1813 RWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPA 1872
+ C + D++F Y+YEY GN +LV TPLTD+CY+TLTQ++ + + G P GPA
Sbjct: 1633 YMKSD-HTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPA 1691
Query: 1873 GTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVL 1932
GTGKTE+ K LG LG V VFNC E +D KS G I+ GL + GAWGCFDEFNR+ VL
Sbjct: 1692 GTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVL 1751
Query: 1933 SVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNP---GYAGRTELPENLKSL 1989
S V++Q+++IQDA+++ + LG+E+ +N + GIFITMNP GY GR +LP+NLK L
Sbjct: 1752 SAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQL 1811
Query: 1990 FRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDWGLRAIKS 2049
FRP AM PD ELI E++L +EGF +A+ L+RK + ++ L +ELL+ Q HYDWGLRA+K+
Sbjct: 1812 FRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKT 1871
Query: 2050 VLVVAGSLKR------GDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFPALDV 2103
VL +G+L R + E +++++LR + K D F LI D+FP +++
Sbjct: 1872 VLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIEL 1931
Query: 2104 PRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQVLRS 2163
A +++ + + N + K ++L E L R V +VG +G GKS + R
Sbjct: 1932 KEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRM 1991
Query: 2164 LH----KTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDGLFSSIMRELANITHD 2219
L KT +++K+ +NPKA+ +L G I+ T EW DG+ ++ R++ D
Sbjct: 1992 LRAALCKTGKVVKQ----YTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQD 2047
Query: 2220 GPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATV 2279
WI+ DGDIDP WIESLN+V+DDN++LT+ S ERI P + +FE L A+PAT+
Sbjct: 2048 VSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATI 2107
Query: 2280 SRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRFKKIIPI 2339
SR G+++++ + N + SW+ + + R NL Y L + K+ +
Sbjct: 2108 SRMGMIFLSDEETDLNSLIKSWLRNQPAE-YRNNLENWIGDYFEKALQWV---LKQNDYV 2163
Query: 2340 PEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMVQDQLVDYRAEFS 2399
E S+V V + L L D F+ I GG + +++ E
Sbjct: 2164 VETSLVGTVMNGLSHLHGCRD----------HDEFIINLIRGLGGNLNMKSRLEFTKEVF 2213
Query: 2400 KWWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQ--FEFDPEMPLQACLVHTSET 2457
W P D Y D + + P+ D L ++ T +
Sbjct: 2214 HW-----ARESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDM 2268
Query: 2458 IR-VCYFMERLMA-RQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAM 2515
R + YF L + ++P +LVG G GK +L+ + L + + V + TTS
Sbjct: 2269 QRGLDYFKPWLSSDTKQPFILVGPEGCGKGMLLRYAFSQL--RSTQIATVHCSAQTTSRH 2326
Query: 2516 LQAVLEKP---LEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGH 2572
L L + + GR Y P ++L+ ++ D+N+P++D +GT ++Q L Y
Sbjct: 2327 LLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQG 2386
Query: 2573 WYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFV----LSFPGADALSSIYS 2628
+YD + L + N+Q V+ M +AG +L F+ V + +P + L +IY
Sbjct: 2387 FYDEN-LEWVGLENIQIVASM--SAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYG 2443
Query: 2629 I----ILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFAN 2684
+L ++LK + S K I L + ++++ F HY F
Sbjct: 2444 AYLEPVLHKNLKNHSIWGSSSK-IYLLAGSMVQVYEQVRAKFTVDDYS-HYFFTPCILTQ 2501
Query: 2685 IFQGILFSSVECVKSTWDL---IRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLK---- 2737
G+ +E S L + + +E+ R++RDK+V K+ LFD I T V +
Sbjct: 2502 WVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWG 2561
Query: 2738 -KTFDDIEDPVEQTQSPNLYCHFANGIGEPKYMPVQSWEL-------LTQTLVEALENHN 2789
D++ D T G+P +P L L + + L ++
Sbjct: 2562 SDILDNMSDSFYVTWGARHNSGARAAPGQP--LPPHGKPLGKLNSTDLKDVIKKGLIHYG 2619
Query: 2790 EVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQI 2849
N +D++LF + + ++ I+R+L P G+ LL G G G++++T L + + +F
Sbjct: 2620 RDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSP 2679
Query: 2850 TLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLY 2909
+ +GY+++ FK DL + AG++ V L+ D Q FL +IN LL+SGE+P LY
Sbjct: 2680 KISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLY 2739
Query: 2910 SDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKF 2969
+ +E+E ++ ++++ G + +F RI++ L + L + +
Sbjct: 2740 TLEELEPLLLPLKDQASQDGFFG---PVFNYFTYRIQQNLHIVLIMDSANSNFMINCESN 2796
Query: 2970 PAIVNCTAIHWFHEWPQQALESVSLRFLQNTEG---------IEPTVKQSISKFMAFVHT 3020
PA+ + W W +++ + T G E K S+
Sbjct: 2797 PALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFL 2856
Query: 3021 SVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTS 3080
++++ ++Y TP ++ F+ +Y ++ +KEL + L+ G+ KL+
Sbjct: 2857 LIHESCKAY--------GATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAK 2908
Query: 3081 AQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVK 3140
A VD+L K Q V LK K ++AD +Q++ V S +K + + ++A +++++
Sbjct: 2909 ALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIE 2968
Query: 3141 QKQKDCEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRG 3200
+++ +++L + +P + A+ A+ + +L+E++S PP + ++ V+ LM
Sbjct: 2969 ERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMG--- 3025
Query: 3201 RVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYL--QDPEFNPEFVATK 3258
D SW + K +AK G + + F+ NI + +++ L F+P+
Sbjct: 3026 --IFDTSWVSMKSFLAK-RGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRA 3082
Query: 3259 SYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLA 3318
S AAA L +WV +++ V + P ++L +++ ++ + + + ++
Sbjct: 3083 STAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVS 3142
Query: 3319 KLTARFEKATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCG 3378
+L +F+ T++ K + E TI A L+ L E+ RW V ++ TL
Sbjct: 3143 ELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPK 3202
Query: 3379 DILLITAFISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAW 3438
L AFI+YL + R++ L+ W T D R L +++ W
Sbjct: 3203 RAQLAAAFITYLSAAPESLRKTCLEE-W--------TKSAGLEKFDLRRFLCTESEQLIW 3253
Query: 3439 QNEGLPADRMSVENATI---LINCERW----PLMVDPQLQGIKWIKNKYGEDLRVTQIGQ 3491
++EGLP+D +S+ENA + +I + W P ++DP Q +W+K + +D R+ I Q
Sbjct: 3254 KSEGLPSDDLSIENALVILQIIGLKSWSRVCPFLIDPSSQATEWLKT-HLKDSRLEVINQ 3312
Query: 3492 K--GYLQIIEQALEAGAVVLIENLEESIDPVLGPLLGREVIKKG--RFIKIGDKECEYNP 3547
+ ++ +E A+ G ++I+ + + ++PVL PLL R+++ +G ++IGDK +YN
Sbjct: 3313 QDSNFITALELAVRFGKTLIIQEM-DGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNE 3371
Query: 3548 KFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTK 3607
+FRL L T+ NP P+ + T +NFT TR GL QLLA + E+PDLE+ K+ L +
Sbjct: 3372 EFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQ 3431
Query: 3608 QQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVK 3667
Q+ KI L LE+SLL L+++ GN L L+E+L TK ++A +++ ++E+ ++
Sbjct: 3432 QEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQIS 3491
Query: 3668 INEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERV 3727
+++ R+ Y P A AS +YFI++DLSKI+ MY+FSL AF +FQ+A++ E+ +R+
Sbjct: 3492 LDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRI 3551
Query: 3728 ANLIDSITFSVYQYTIRGLFECDKLTYLAQLT-------FQILLMNREVNAVELDFLLRS 3780
+LI S+ VY+Y R LF+ D+L + FQ + V D L ++
Sbjct: 3552 QSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKA 3611
Query: 3781 PVQTGTAS--PVEFLSHQAWGAVKVLSSMEE-FSNLDRDIEGSAKSWKKFVESECPEKEK 3837
Q P ++W + ++ + L + A W+ + + E+E
Sbjct: 3612 DSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFE---DAALWRTYYNNSMCEQEF 3668
Query: 3838 LPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPAT 3897
K + Q++ +++A+RPDR+ A+ F + LG K V L+ ++E+
Sbjct: 3669 PSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIE 3728
Query: 3898 PMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVI 3957
P+ I+SPG DP ++++ + + +H V++GQGQ +A L A+ G W+
Sbjct: 3729 PILIIISPGADPSQELQELANA---ERSGECYHQVAMGQGQADLAIQMLKECARNGDWLC 3785
Query: 3958 LQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNE 4017
L+N+HLV WL LEK+L ++ FR++++AE P+ +L++S+KIT E
Sbjct: 3786 LKNLHLVVSWLPVLEKEL--NTLQPKDTFRLWLTAEVHPN-----FTPILLQSSLKITYE 3838
Query: 4018 PPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYP 4077
P G+ NL + +++T + + T LF+L +FHA ERR + PQGW + Y
Sbjct: 3839 SPPGLKKNLMRTYESWTPEQISK-KDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYE 3897
Query: 4078 FNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRP 4137
F+ DL N++ + V ++ + L +YGG I + +D R+ ++YL +F
Sbjct: 3898 FSLSDLRAGYNIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNS 3957
Query: 4138 EMLE-----GELSLAP-GFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQT 4191
+++ + S+ P LP + Y I+ + P +GL N + ++
Sbjct: 3958 SVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPAN-----IARS 4012
Query: 4192 SEKLFRTVLELQPRDSQARDGAGATREEKV----KALLEEILERVTDEFN-IPELMAKVE 4246
S+++ + + Q R AG+ + ++ + + + +++ N I + +
Sbjct: 4013 SQRMISSQVISQLRILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPN 4072
Query: 4247 ERTPYIVVAFQECGRMNI--LTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPE 4304
+R +++F + N L + + +SL L ++G ++S ++ L +AL P
Sbjct: 4073 DRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPL 4132
Query: 4305 SWARRAYPSTAGLAAWFPDLLNRIKELEAWTG----DFTMPSTVWLTGFFNPQSFLTAIM 4360
+W + + + L+ R ++ W + T+ L+ F+P +FL A+
Sbjct: 4133 AWQSK-WEGPEDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALR 4191
Query: 4361 QSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKL 4420
Q TAR +D + + +E + I GL +EG +D +
Sbjct: 4192 QETARAVGRSVDSLKFVASWKGRLQE-----AKLQIKISGLLLEGCSFDGNQLSENQLDS 4246
Query: 4421 KDLTPPMPVMFIKAIPADKQDCRSVYSC---PVYKTSQRGPTYVWTFNLKTKENPSKWVL 4477
++ +P F+ IP D S C PVY +++R V ++ N +W+
Sbjct: 4247 PSVSSVLP-CFMGWIPQDACGPYSPDECISLPVYTSAER-DRVVTNIDVPCGGNQDQWIQ 4304
Query: 4478 AGVALLLQ 4485
G AL L+
Sbjct: 4305 CGAALFLK 4312
Score = 45.4 bits (106), Expect = 0.001
Identities = 46/280 (16%), Positives = 119/280 (42%), Gaps = 18/280 (6%)
Query: 553 LLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVH-KNMPTVAGGL 611
L++RP ++++ + L+ + R+ + + P+ KN+ V +
Sbjct: 427 LVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSI 486
Query: 612 RWAQELRQRIQGPFSNFGRITHPCMESAEGKR-MQQKYEDMLSLLEKYETRLYEDWCRTV 670
W ++L ++ +I + G R Q +D+L L+ YE ++DW R +
Sbjct: 487 VWVRQLELKVDDTI----KIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDI 542
Query: 671 S---EKSQYNL----SQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAA 723
S+ L S +++ D + ++++ +L+ +L+E+ L +
Sbjct: 543 QSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQ 602
Query: 724 AMFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKT 783
++ F +Q + L+ +A++YN + + +++ + P++ + + ++ ++ K+
Sbjct: 603 VANIAQKFCKQAII-LKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGKS 661
Query: 784 EGICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVT 823
+ D E+ I Q++Q + + ++ W T
Sbjct: 662 QITWDNPKELEGYI----QKLQNAAERLATENRKLRKWHT 697
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 969 bits (2505), Expect = 0.0
Identities = 647/2042 (31%), Positives = 1047/2042 (51%), Gaps = 160/2042 (7%)
Query: 918 PIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLVPRLSPQNGSPHYQV 977
PIF+ +L+ ++ FYP+ + ++ +VE + ++ + ++ LS + +
Sbjct: 324 PIFKIELTFDDDKMEFYPTFQD-LEDNVLSLVERIAEALQNVQTIPSWLSGTSTPVNLDT 382
Query: 978 DLDGIPD--LANMRRTLMERVQRMM-GLCCGYQSTFSQYSYLYVEDRKEVLGQFLLYGHI 1034
+L P+ L TL V R + G Y++ +Y++L E + F
Sbjct: 383 EL---PEHVLHWAVDTLKAAVHRNLEGARKHYETYVEKYNWLLDGTAVENIETF------ 433
Query: 1035 LTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDGWMKIDIRPFKA 1094
+ EDH D ++ I+ + +L E+ L P + +++D K
Sbjct: 434 ----QTEDHTFD----------EYTEFIEKFLSLASEIMLL-PQWIHYTMVRLDCEDLKT 478
Query: 1095 SLLNIIKRWSLLFKQHLVDHVTHS----LANLDAF----IKKSES-----GLLKKVEKGD 1141
L N K ++ + + + +A +K E+ L+ VEK
Sbjct: 479 GLTNKAKAFANILLNDIASKYRKENECICSEFEAIKEHALKVPETTEEMMDLISYVEKAR 538
Query: 1142 FQGLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKT---YEQELPETVFKQLEELPEKW 1198
G+ E++ + K + S ++F ++ + L T + +++ +F + +EL E
Sbjct: 539 TVGIEELILRIQESKRQMSYFLDVFLFPQEDLALNATVLMWPRKI-NPIFDENDELIENA 597
Query: 1199 NNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQML 1258
+ K+ + K++ L+ + + + T F AE ++ + +
Sbjct: 598 KHKKENELMAKREKLILEIEKESRRMEEFTEF-AELERMQQY----------------VT 640
Query: 1259 DARHIE--IQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSI 1316
D R ++ IQ+ E + I++ LF+ + Y +L + + + ++ ++ + S
Sbjct: 641 DVRQLQKRIQESEEAVQFINKEEELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSE 700
Query: 1317 HAWETTPWRNINVEAMELECKQFARHI--------RNLDKEVRAWDAFTGLESTVWNTLS 1368
W + ++N E+ME + ++F+R I L KE++ S +
Sbjct: 701 KRWMDGGFLDLNGESMEADVEEFSREIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIE 760
Query: 1369 SL-RAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKA 1427
+ A + +R RHW+Q+ + G T D TTL +L+L L Y ++ I A
Sbjct: 761 EEPKDNATITMCRMRARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGA 820
Query: 1428 AKEMGMEKTLKELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKY 1487
+KE +EK + + TW + F + T V +L S +++ +L+D ++ Q + S +
Sbjct: 821 SKEFSLEKAMNTMIGTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPF 880
Query: 1488 VAFFLEEVSGWQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGID 1547
+ F E+ W+ +L + I W +VQ W +LE IF SEDI Q+P++ ++F+ +D
Sbjct: 881 IKPFEHEIKAWEDRLIRIQETIDEWLKVQAQWLYLEPIFC-SEDIMQQMPEEGRQFQTVD 939
Query: 1548 IDFKELAYDAQKIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFL 1607
++++ K P V+ T+ GL EKL++ L K L YL+ KRL FPRF+FL
Sbjct: 940 RHWRDIMKFCAKDPKVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFL 999
Query: 1608 SSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYV--- 1664
S+ ++L+ILS P +VQ HL K F+ +AK+ F P MYS E E V
Sbjct: 1000 SNDEMLEILSETKDPLRVQPHLKKCFEGIAKLEFL------PNLDIKAMYSSEGERVELI 1053
Query: 1665 AFSEPCDCSGQVEIWLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQ 1724
A G VE WL V M +V + AY E R W+ + P QV L +Q
Sbjct: 1054 ALISTSAARGAVEKWLIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQ 1113
Query: 1725 IWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDV 1784
++WT+E + EG +K YYK+ QL ++ ++ G+LSK R + + TIDV
Sbjct: 1114 MFWTSETQEVISGGTEG----LKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDV 1169
Query: 1785 HARDVVAKMIAQKVDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLV 1844
HARDVV MI V + FLWL+QLR+ W++E + I + Y+YEYLGN+PRLV
Sbjct: 1170 HARDVVMDMIKMGVSHDTDFLWLAQLRYYWENE--NARVRIINCNVKYAYEYLGNSPRLV 1227
Query: 1845 ITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKS 1904
ITPLTDRCY TL + +L + GAP GPAGTGKTETTKDL +AL + VFNCS+ +DY +
Sbjct: 1228 ITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLA 1287
Query: 1905 CGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNP 1964
G +KGLA +GAW CFDEFNRI +EVLSVVA Q+ IQ AI+ K F F G E+ LNP
Sbjct: 1288 MGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNP 1347
Query: 1965 SVGIFITMNPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFI 2024
+ + ITMNPGYAGR+ELP+NLK LFR AM+VP++ LI EI L + GF+ A+ L+ K +
Sbjct: 1348 NCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIV 1407
Query: 2025 TLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVT 2084
Y+LC E LS Q HYD+G+RA+K+VLV AG+LK P+ ED +L+RS++D N PK ++
Sbjct: 1408 MTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLS 1467
Query: 2085 DDMPIFMGLIGDLFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVR 2144
D+P+F G+ DLFP + +P F +A LQ F+ K++Q E++ VR
Sbjct: 1468 HDIPLFNGITSDLFPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVR 1527
Query: 2145 HSVFVVGGAGTGKSQVLRSLHKTYQIM-------KRRPVWTDLNPKAVTNDELFGIINPA 2197
H +VG K++VL L T +M + + ++ +NPK++T +LFG +P
Sbjct: 1528 HGFMLVGEPFAAKTKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPV 1587
Query: 2198 TGEWKDGLFSSIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIP 2257
+ EW DG+ ++ RE A KW++ DG ID +WIES+NTV+DDNK L L S E I
Sbjct: 1588 SHEWTDGIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQ 1647
Query: 2258 LNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKRE---IQTE-RAN 2313
++P M L+FE L A+PATVSR G++Y+ P+ LGW P VSSW+ + + E +A
Sbjct: 1648 MSPQMSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQAL 1707
Query: 2314 LTILFDKYLPTCLDTLRTRFKKIIPIPEQSMVQMVCHLLECLLT------TEDIPADCPK 2367
L LF +P L+ F+ +V +L+ L+T + +P
Sbjct: 1708 LRGLFAWLIPPSLNQRVELFQL-----NYLYTTIVSKILKILITFRISNYFKYVPLKTQC 1762
Query: 2368 EIYEHY------FVFAAIWAFGGA-----------------MVQDQLVDYRAEFSKWWLT 2404
+ + F+F+ IW+ GG+ + +D KW
Sbjct: 1763 TFIKFFLHQQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKW--- 1819
Query: 2405 EFKTVKFPSQGTIFDYYIDPETK-KFEPWSKLVPQFEF-DPEMPLQACLVHTSETIRVCY 2462
F +G ++DY + + K ++ W++L+ D ++ +Q +V T +TIR +
Sbjct: 1820 ---ECPFDEKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTF 1876
Query: 2463 FMERLMARQRPVMLVGTAGTGKSVLVGAKLAS-LDPEAYLVKNVPFNYYTTSAMLQAVLE 2521
M+ + +P++ VG GTGKSV V KL + L+ + Y + + T++ +Q ++
Sbjct: 1877 LMDLSITYAKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIM 1936
Query: 2522 KPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQHLDYGHWYDRSKLSL 2581
L+K+ +GPP KK I FIDDMNMP ++ YG P ++RQ D GHWYD S
Sbjct: 1937 ARLDKRRKGVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSK 1996
Query: 2582 KEITNVQYVSCMNPTAGSFT-INPRLQRHFSVFVLSFPGADALSSIYSIILTQHLKLGNF 2640
+ +++ ++ M P G + PR RHF++ ++ + + I+S I+ +L+ F
Sbjct: 1997 ITLVDIELIAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEF 2056
Query: 2641 PASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQGILFSSVECVKST 2700
P +++ + +++ LPT K HY FNLRDF+ + +G L + V +
Sbjct: 2057 PPEYFVIGNQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANK 2116
Query: 2701 WDLIRLYLHESNRVYRDKMVEEKD----FDLFDKIQTEVLKKTFDDI-------EDPVEQ 2749
+IRL++HE RV+ D+++ + D F L + + K++F I PV +
Sbjct: 2117 HTMIRLFVHEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTE 2176
Query: 2750 TQSPNL----YCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVN-TVMDLVLFEDAM 2804
NL Y + + Y+ + + + + + L+ +N+ + T M+LV+F +
Sbjct: 2177 EDLRNLMFGDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVL 2236
Query: 2805 RHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDL 2864
H+ I R+L+ GNALLVG+GGSG+QSLTRLA ++ M +FQ + K Y + +++ D+
Sbjct: 2237 EHLSRICRVLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDM 2296
Query: 2865 AS 2866
S
Sbjct: 2297 KS 2298
Score = 436 bits (1122), Expect = e-121
Identities = 274/843 (32%), Positives = 429/843 (50%), Gaps = 43/843 (5%)
Query: 3672 REHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDES--LRERVAN 3729
R+ A + ++ ++SK + M ++ S + R ++S L +R+
Sbjct: 2263 RQSLTRLATSMAKMHIFQPEISKSYGMNEWREDMKSFIAVPVTNRIVDNKSKILEKRLRY 2322
Query: 3730 LIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASP 3789
L D T+++Y R LFE DKL + L +LL +E+ EL FLL V +A
Sbjct: 2323 LNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIEYQELMFLLTGGVSLKSAEK 2382
Query: 3790 ---VEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEW-KNK 3845
+L ++W + S F L + W++ +S+ P K P KN
Sbjct: 2383 NPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREIYDSKEPHNAKFPAPMDKNL 2442
Query: 3846 TALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSP 3905
LQ++ +LR +RPD++T A+ ++V +KLG K+V D S+ +S P+ F+LSP
Sbjct: 2443 NELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDLTKSYLDSNCTIPLIFVLSP 2502
Query: 3906 GVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVA 3965
G DP+ + + N F +SLGQGQ +A + A ++G WV LQN HL
Sbjct: 2503 GADPMASLLKFANDKSMSGNK--FQAISLGQGQGPIAAKMIKAAIEEGTWVCLQNCHLAV 2560
Query: 3966 KWLSTLEKKLEEH-SENSHPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHA 4024
W+ LEK E+ SE + FR+++++ P+ P IL+N +K+TNEPPTG+
Sbjct: 2561 SWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPVTILQNGVKMTNEPPTGLRL 2615
Query: 4025 NLHKALDNFTQDTLE-------MCSRETEFKSILFALCYFHAVVAERRKFGPQGWNRSYP 4077
NL L ++ D + +E ++ +LF +C+FHA+V ER+KFGP GWN Y
Sbjct: 2616 NL---LQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALVQERKKFGPLGWNIPYG 2672
Query: 4078 FNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLGEFIRP 4137
FN DL IS+ L F+ +P++ + YL GE YGG +TDDWDRRL T L +F
Sbjct: 2673 FNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDDWDRRLLLTMLADFYNL 2732
Query: 4138 EMLEG---ELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIGFLTQTSEK 4194
++E + S + + P Y Y ++I + P ++GLH N +I Q ++
Sbjct: 2733 YIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFGLHENVDISKDLQQTKT 2792
Query: 4195 LFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAK--VEERTPYI 4252
LF ++L Q Q GA + ++ + + ++IL ++ +F+I + K V
Sbjct: 2793 LFESLLLTQGGSKQT--GASGSTDQILLEITKDILNKLPSDFDIEMALRKYPVRYEESMN 2850
Query: 4253 VVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYP 4312
V QE R N L I+ +LR+LE +KG + M S +E L +L VPE WA+R+YP
Sbjct: 2851 TVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGSLLVGKVPEIWAKRSYP 2910
Query: 4313 STAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARKNEWPLD 4372
S L ++ D L R+ L+ W P WL+GFF Q+FLT MQ+ ARK P+D
Sbjct: 2911 SLKPLGSYITDFLARLNFLQDWYNS-GKPCVFWLSGFFFTQAFLTGAMQNYARKYTTPID 2969
Query: 4373 QMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFI 4432
+ + ++ + + + P +G YIHGL+++GA WD ++G++ E K L MP+++I
Sbjct: 2970 LLGYEFEVIPSDTSD--TSPEDGVYIHGLYLDGARWDRESGLLAEQYPKLLFDLMPIIWI 3027
Query: 4433 KAIPADKQDCRSVYSCPVYKTSQRGPT---------YVWTFNLKTKENPSKWVLAGVALL 4483
K + Y CP+YKTS+R T +V LKT + W+ GVALL
Sbjct: 3028 KPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLKTDQPTRHWIKRGVALL 3087
Query: 4484 LQI 4486
Q+
Sbjct: 3088 CQL 3090
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 754 bits (1947), Expect = 0.0
Identities = 586/2206 (26%), Positives = 1012/2206 (45%), Gaps = 323/2206 (14%)
Query: 2492 LASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPE 2551
L + D + +V + F+ T+A + ++ K L ++ G P N +++ FIDDMNMP
Sbjct: 2417 LKNNDHKGVVVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPV 2476
Query: 2552 VDAYGTVQPHTIIRQHLDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFS 2611
D YG P +IRQ LD G YD K + K I ++ V+ P I+PRL +HFS
Sbjct: 2477 SDMYGAQPPLELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVND--ISPRLLKHFS 2534
Query: 2612 VFVLSFPGADALSSIYSIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGI 2671
+ VL P D L +I+ L + + NF +QKS +I +LA + ++ LPT
Sbjct: 2535 MLVLPHPSQDILCTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPT 2594
Query: 2672 KFHYIFNLRDFANIFQGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKI 2731
K HY+FNLRD + G+L + V S L++HE+ RV+ D++++ D LF ++
Sbjct: 2595 KCHYMFNLRDMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRL 2654
Query: 2732 QTEVLKKTFDDIEDPVEQTQSPNLYCHFANG-----IGEPKYMPVQSWELLTQTLVEA-L 2785
+ L+ F D + L C+ + K ++ E+ + + A L
Sbjct: 2655 LSRELENCFQIGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHAGL 2714
Query: 2786 ENHNEVNTVMDLVLFEDAMRHVCHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMD 2845
+ V V +L + +D+ +N I+ S R L V L +A M
Sbjct: 2715 KGKPTVLMVPNLNIEQDSFLE--DLNYIISSGRIPDLFENV------ELDSIA-----MK 2761
Query: 2846 VFQITLRKGYQIQDFKMDLASLCLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEI 2905
+ +T + G+ D + L S K KNL+ +M+ + + + +++S I
Sbjct: 2762 IRYLTEQSGH--MDNRQSLLSFFQKRIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTI 2819
Query: 2906 PDLYSDDEVENIISNVRNEVKSQGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVR 2965
D Y E ++ + +K + +NREN ++ +L T
Sbjct: 2820 -DWYERWPEEALLIVANSFLKEKVNFENREN--------LKEKLAPT------------- 2857
Query: 2966 SRKFPAIVNCTAIHWFHEWPQQALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQT 3025
C IH ++++ ++ ++ + T F +T+ N
Sbjct: 2858 ---------CVQIH-------KSMKDLNRKYFEETG--------------RFYYTTPN-- 2885
Query: 3026 SQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDD 3085
S+L+F+ + +L +E++ K +R GL + + V +
Sbjct: 2886 -----------------SYLQFMETFAHILRAREEEMQTKRDRFHMGLSTILEATTLVTE 2928
Query: 3086 LKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKD 3145
++ +L +++QK ++ + L++ + ++ V + + + ++E+ VA + V+ +
Sbjct: 2929 MQEELLILGPQVEQKTKETETLMEKLRKDSQVVEKVQMLVKQDEEIVAEEVRIVEDYAQK 2988
Query: 3146 CEEDLAKAEPALTAAQAALNTLNKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKD 3205
+L PA A ALN L+K ++ EL+ + PP V V AV +L+ K
Sbjct: 2989 TANELKSVLPAFDKAIVALNALDKADVAELRVYTRPPFLVLTVMNAVCILL------QKK 3042
Query: 3206 RSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAGL 3265
+W AK+ +++ GFL LIN +K++I + ++ + P+FNP ++ S A L
Sbjct: 3043 PNWATAKLLLSET-GFLKKLINLDKDSIPDKVFVKLKKIVTLPDFNPHKISLVSVACCSL 3101
Query: 3266 CSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFE 3325
C WVI + ++EV V PK+ + +A L A+++LA + + + E+L L A ++
Sbjct: 3102 CQWVIALNNYHEVQKVVGPKQIQVAEAQNVLKIARQRLAEKQRGLQLVEEHLLFLQAAYK 3161
Query: 3326 KATADKLKCQQEAEVTAVTISLANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITA 3385
A+K + + A+ L+ L E RW + + + + GDILL A
Sbjct: 3162 DTVAEKQLLANRKTMASRRFQCASVLLTVLEDEKTRWQETINQIDNKLEGILGDILLSAA 3221
Query: 3386 FISYLGFFTKKYRQSLLDRTWRPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPA 3445
I Y G T ++RQ ++++ W + ++ I ++ ++++ +++ W N+GLP
Sbjct: 3222 CIVYSGILTPEFRQLIVNK-WETFC--IENGISLSSKFSLIKVMAQKYEISRWHNQGLPH 3278
Query: 3446 DRMSVENATILINCERWPLMVDPQLQGIKWIKNKYGEDLRVTQIGQKGYLQIIEQALEAG 3505
+ SVENA ++ N ++WPL++DP Q KWI+ G L+ I Y + IE A++ G
Sbjct: 3279 GQYSVENAILIKNGQQWPLLIDPHRQAHKWIRQMEGSRLQKLSIEDSNYTKKIENAMKTG 3338
Query: 3506 AVVLIENLEESIDPVLGPLLGREVI-KKGR-FIKIGDKECEYNPKFRLILHTKLANPHYQ 3563
VL++NL E++ P L +L +++ KKG FI++GD E EYN FRL L T++ NPH+
Sbjct: 3339 GSVLLQNLLETLAPGLKAILKKDIYQKKGHYFIRVGDAEFEYNSNFRLYLSTEIDNPHFL 3398
Query: 3564 PELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSL 3623
P + T+INFTVT GL+DQLL+ VV+ E P LE +S L + + ITL+ LE+
Sbjct: 3399 PSVYNFVTMINFTVTFQGLQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKT 3458
Query: 3624 LSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARAS 3683
L+ L A G+ L + +V+ L +K T+ E+ K+++ K E +I R++Y P A R +
Sbjct: 3459 LNLLQKALGSILDDDKIVDTLRKSKMTSNEISKRIEATKKAESEIQAIRKNYLPIATRGA 3518
Query: 3684 LLYFIMNDLSKIHPMYQFSLKAFSIVFQKAV-------------ERAAPDE--------- 3721
LLYF++ DL++I+ MYQFSL F VF +V E+ +P E
Sbjct: 3519 LLYFLVADLTQINYMYQFSLDWFHQVFVSSVVSKSKEQEHSFKREKVSPKEVHEFISISK 3578
Query: 3722 ---------SLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMNREVNAV 3772
L + + + ID +T S+++ LF DKL + +L I+ N N +
Sbjct: 3579 EPNLENEKNLLDKHIKSAIDMLTKSIFKVVSSALFNEDKLCFSFRLCTVIMQNNANGNLI 3638
Query: 3773 ELD--FL-------------------------LRSPVQTGTASPVEFLSHQAWGAVKVLS 3805
+ D FL L S + G + +++LS W + +S
Sbjct: 3639 QDDIGFLPEEEWNIFLYSGILINIKSALSQSRLTSTFEIGESQHLQWLSDSRWRQCQYVS 3698
Query: 3806 S-MEEFSNLDRDIEGSAKSWKKFVESEC----------------PEKEKLPQE------- 3841
+ +E FS L + + + W F S+ E K P+E
Sbjct: 3699 THLEPFSLLCKSLLSNVSQWDTFKNSKAVYSLISTPFSSENASLEENTKPPEETELLNEN 3758
Query: 3842 ----------WKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFATSFE 3891
W+ T+ QRL +++ +RP+ + ++R F+ EK+G+KY+ ++ +++
Sbjct: 3759 KETCNPINFPWEKLTSFQRLILVKVLRPESLNNSVRKFITEKMGNKYLQRTGVNLKDAYK 3818
Query: 3892 ESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAE-AALDLAA 3950
S TP+ I + G+D + ++L T ++ +SLG+ Q AE L
Sbjct: 3819 GSNARTPLILIQTHGIDLTNILLRFAQELKGTTHHVTI--ISLGRDQAAKAEDLILKALT 3876
Query: 3951 KKGHWVILQNIHLVAKW---LSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQGI 4007
K WV LQN HL + L T+ + + PEFR+++S++ S P +
Sbjct: 3877 KTQQWVFLQNCHLATSFMPRLCTIVESFNSPNVTIDPEFRLWLSSKSYSS-----FPIPV 3931
Query: 4008 LENSIKITNEPPTGMHANLHKAL-----DNFTQDTLEMCSRETEFKSILFALCYFHAVVA 4062
L+ +KI E P G+ +NL + T++ E +K +LF+LC+F+AV+
Sbjct: 3932 LKKGLKIAVESPQGLKSNLLQTFGCTGSGEVTEEIFENPDCGQWWKKLLFSLCFFNAVIN 3991
Query: 4063 ERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDW 4122
ER+ +G GWN +Y FN+ DL +++ VL N L + + LRYL GE++YGG + D+W
Sbjct: 3992 ERKNYGILGWNIAYKFNSSDLGVAIKVLENSLRGQPSISWQALRYLIGEVIYGGRVIDNW 4051
Query: 4123 DRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPN 4182
D+R +T L +F PE+L+ + S + + Y I + + P + G+HP
Sbjct: 4052 DKRCLKTLLYKFCNPEVLKDDFSFS------RSASIKDYIHIIQSLPDDDLPEVLGIHPE 4105
Query: 4183 AEIGFLTQTSEKLFRTVLELQPRDSQAR--DGAGATREEKVKALLEEILERV-----TDE 4235
A EK ++ +QP+ + A +++E V +L ++L+R+ +E
Sbjct: 4106 AIRSCWETQGEKFIENLIAMQPKTTTANLMIRPEQSKDELVMEILSDLLKRLPLTVEKEE 4165
Query: 4236 FNI---------------PELMAKVEERTPYI---VVAF--QECGRMNILTREIQRSLRE 4275
+ L +++ P I ++ F QE R + L I +SL++
Sbjct: 4166 IAVGTPSTLKSMMSSSIWESLSKNLKDHDPLIHCVLLTFLKQEIKRFDKLLFVIHKSLKD 4225
Query: 4276 LELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWT 4335
L+L +KGE+ +T +E + N+ VP W + AY S L++W DL+ R+ W
Sbjct: 4226 LQLAIKGEIILTQELEEIFNSFLNMRVPTLWQKHAYRSCKPLSSWIDDLIQRLNFFNTWA 4285
Query: 4336 ------------------------------------GDF--TMPSTVWLTGFFNPQSFLT 4357
+F PS WL FF PQ+FL
Sbjct: 4286 KVAYTAIQRRYMRFVTVWKQSIPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLA 4345
Query: 4358 AIMQSTARKNEWPLDQMALQ----CDMTKKN--------------REEFR--SPPREGAY 4397
A++Q R +D + + T K+ R F+ + G Y
Sbjct: 4346 AVLQDYGRSRGIAVDALTFTHHVISNTTDKDEKFSVFMPKKLNIVRRAFKGSASSHTGVY 4405
Query: 4398 IHGLFMEGACWDTQAGIITEAKLKDLTPPMPVMFI-------KAIPADKQDCRSVYS--C 4448
I GLF+EGA W+ + I+ ++ ++ P ++ K A Q +Y+ C
Sbjct: 4406 IFGLFIEGARWNREQKILEDSLPLEMCCDFPDIYFLPTKISTKTPNASNQTDSELYAFEC 4465
Query: 4449 PVYKTSQRG--------PT-YVWTFNLKTKENPSKWVLAGVALLLQ 4485
PVY+T +R PT ++ + L TK+ PS W+ VALL +
Sbjct: 4466 PVYQTPERSRILATTGLPTNFLTSVYLSTKKPPSHWITMRVALLCE 4511
Score = 620 bits (1600), Expect = e-177
Identities = 426/1423 (29%), Positives = 692/1423 (48%), Gaps = 206/1423 (14%)
Query: 1266 QQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWR 1325
Q S S S ++ E+ ++ ++ K+LW+ + W + +
Sbjct: 963 QDCFSDSQSHMHSVNVEEITQIVLSEISDIEGDLTLRKKLWEAQEEWKRASWEWRNSSLQ 1022
Query: 1326 NINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERH 1385
+I+VE+++ + I L+K + D T L+ V L + L NP ++ RH
Sbjct: 1023 SIDVESVQRNVSKLMHIISVLEKGLPKSDMVTHLKQVVTEFKQELPIIIALGNPCLKPRH 1082
Query: 1386 WRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWA 1445
W L + G S +D++ + +LL L++ YE+E+ + A E +EK L ++ W
Sbjct: 1083 WEALQEIIGKSVPLDKNCKVENLLALKMFQYENEINDMSTSATNEAALEKMLFKIIDFWN 1142
Query: 1446 GMEFQYEPHPRT--NVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLS 1503
H ++ ++ S +D+ LE++QV L + S ++ + V+ W + L+
Sbjct: 1143 TTPLPLILHHTEIYSIFIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLT 1202
Query: 1504 TVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQKIPNV 1563
+ W QR W +LE +F SE IR QLP +++ F + +K++ Q N
Sbjct: 1203 LFSYTLEEWMNCQRNWLYLEPVFHSSE-IRRQLPAETELFSQVISMWKKIMSKIQNKQNA 1261
Query: 1564 VQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQ 1623
+Q T G+ E L++ L +K+L +YL+ KRL FPRFYFLS+++LLDIL++ P+
Sbjct: 1262 LQITTSAGVLEILQNCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLDILADSRNPE 1321
Query: 1624 QVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEIWLNHV 1683
VQ HL K F+N+ ++ G P L S E E + + VE WL +V
Sbjct: 1322 SVQPHLVKCFENIKQLLIWKQDIGPPAVKML--ISAEGEGLVLPKKIRVRSAVEQWLVNV 1379
Query: 1684 LGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARLEEGYE 1743
M ++ +E+++++ + L +QI + + +F +
Sbjct: 1380 EKSM--------------FDVLKKERYIYNI---ILLFQSQIMFYNDCVKSF--VSSYSR 1420
Query: 1744 SAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIM-TICTIDVHARDVVAKMIAQKVDNAQ 1802
++ + + L+ + +++ S + I+ + + VH RD+V ++ + + NA+
Sbjct: 1421 EKLEKVHAGLMCHLEEVADLVVLDTSNSRTKAILGALLILYVHCRDIVINLLLKNIFNAE 1480
Query: 1803 AFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHL 1862
F W L+++W+++ K C+ + +A F Y YEYLG T RLVITPLTDRC++TL ++LHL
Sbjct: 1481 DFEWTRHLQYKWNEKQKLCYVSQGNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHL 1540
Query: 1863 TMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFD 1922
+ G PAGPAGTGKTET KDL ++LG VFNC E +DYK + GL Q+GAW CFD
Sbjct: 1541 NLGGCPAGPAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFD 1600
Query: 1923 EFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGYAGRTEL 1982
EFN I +EVLSV+A Q+ +I+ A + F G+EI +N S +FITMNP Y G EL
Sbjct: 1601 EFNLIDLEVLSVIASQILTIKAAKDNYSARFVLEGKEIRINMSCAVFITMNPRYGGGVEL 1660
Query: 1983 PENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSKQDHYDW 2042
P+NLKSLFRP AM+VP +++I EI+L + GF A SL+ K LY+L ++ LS+QDHY++
Sbjct: 1661 PDNLKSLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNF 1720
Query: 2043 GLRAIKSVLVVAGSLKRGD---PDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGDLFP 2099
GLR++K VL++AG+ KR + E +++ ++R+ ++PK +D+P+F +IGD+FP
Sbjct: 1721 GLRSLKIVLIMAGTKKREFKCLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFP 1780
Query: 2100 ALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTGKSQ 2159
+ V + E ++ A L LQ + K++Q L V V +VG G GK+
Sbjct: 1781 EVTVLKVNQLALEKVIYTATQQLGLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTT 1840
Query: 2160 VLRSLHKTYQIM--------------------KRRPVWTDLNPKAVTNDELFGIINPATG 2199
V R L K ++ K + LNPK VT EL+G ++P T
Sbjct: 1841 VRRILEKALTLLPIADFLSVAERKSASKISERKGKVDICVLNPKCVTLSELYGQLDPNTM 1900
Query: 2200 EWKDGLFSSIMR------------------------ELANI----------THDGP---- 2221
EW DGL S+ +R +L+N+ T D
Sbjct: 1901 EWTDGLLSATIRSYVYFNTPKNTKKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEI 1960
Query: 2222 --------------KWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFE 2267
+WI+LDG +D W+E+LN+V+DD + L LA++ERI L ++++FE
Sbjct: 1961 EKVVKIPENHNFDWQWIILDGPVDTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFE 2020
Query: 2268 ISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERAN---LTILFDKYLPT 2324
+ +L A+PATVSR ++Y++P DLGW P V SW+ K ++ L + +
Sbjct: 2021 VDNLSQASPATVSRCAMVYMDPVDLGWEPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTD 2080
Query: 2325 CLDTLRTRFK-KIIPIPEQSMVQMVCHLLECL---------------------------- 2355
L +R R K + P+ + ++V +C +L+
Sbjct: 2081 GLQFIRNRQKFQPYPMEDITVVITLCRILDAFFDFMGKNGGFEQSDDLNDTSSKEANSQR 2140
Query: 2356 --LTTEDIP------------ADCPKEIYEHYFVFAAIWAFGGAMVQ------------- 2388
+T +DI D +I + FVFA WAFGGA+ +
Sbjct: 2141 ESVTFKDIEKRDENTWYPEKNPDKLTKIIQKLFVFAFTWAFGGALNREDEHRENIPFCPS 2200
Query: 2389 ---DQLVDYRAEFSK----------------WWLTEFK-----TVKFPS-QGTIFDYYID 2423
D L +F K W ++ + + P+ + +IF Y++D
Sbjct: 2201 LEPDSLAKVTYDFDKLVHELFGNSSQVGWKHWGQSQGRRRKGNCINLPTGECSIFGYFVD 2260
Query: 2424 PETKKFEPWSKLVPQFE-------------------FDPEMPLQACLVHTS--ETIRVCY 2462
E +F PWS LVP + F C+ +T+ +T + +
Sbjct: 2261 IEQCEFIPWSDLVPNDQTLIQRGTSLLTNLQRSGGNFLKITECGECINYTATRDTTCLSF 2320
Query: 2463 FMERLMARQRPVMLVGTAGTGKSVLVGAKLASLD-PEAYLVKN 2504
M L+ PV+L G +G GK+ + L L+ P A+ +K+
Sbjct: 2321 LMSLLLKNSCPVLLTGESGVGKTAAINQMLEKLEGPGAFDIKH 2363
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 184 bits (466), Expect = 2e-45
Identities = 322/1617 (19%), Positives = 617/1617 (38%), Gaps = 307/1617 (18%)
Query: 1389 LMQATGV-SFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLKELQTTWAGM 1447
L++A G+ S + TL LL L + D + + + + ++T++ LQ W
Sbjct: 1106 LLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEAR 1165
Query: 1448 EFQ---------YEP--HPRTNVPLLCSDE-DLIE------VLED-----NQVQLQNLVM 1484
+ + YEP R+ +L S + ++++ +L D + +Q V+
Sbjct: 1166 QLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVL 1225
Query: 1485 SKYVAFFLEEVSG--------WQKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQL 1536
SK +A E SG W + + A++ +W Q+ W L + +++ Q
Sbjct: 1226 SKILAI---EKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWIFLNKVL---HEMKIQF 1279
Query: 1537 PQD--SKRFEGIDIDFKEL----AYDAQKIPNVVQTTNKPGLYEKLE----------DIQ 1580
P + RF+ +D ++ L D + VV + + ++ + +++
Sbjct: 1280 PNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQGQQLQQLLQAGSVELE 1339
Query: 1581 GRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSNGTAPQQVQRHLSKLFDNMAKMR 1640
G + E L FPR +FLS S+L+ +L+ + Q + + F ++ +
Sbjct: 1340 GIIMSLESVLYGVC----AHFPRLFFLSDSELVALLAARLESCEAQLWVRRCFPHVHAVS 1395
Query: 1641 FQLDASGEP----------TKT---SLGMYSKEEEYVAFSEPCDCSGQVEIWLNHV---- 1683
F+ +GE T+T +L + E V P + WL +
Sbjct: 1396 FRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPDLPKWLASLEKCL 1455
Query: 1684 ---LGHM-KATVRHEMTEGVT---AYEEKPREQWLF-------------DHPAQVALTCT 1723
L HM + V + G + A ++ P++ L+ P Q L
Sbjct: 1456 RLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQAFPWQCVLVAE 1515
Query: 1724 QIWWTTEVGMAFARLEEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTI---- 1779
++ W E M A LE G + + + +K L+ L+ + Q + Q + ++
Sbjct: 1516 EVVWRAE--MEEALLEWGTLAMVSMHMRK----LEVLVNFMRAQRASQGGQSLPSVRQTS 1569
Query: 1780 -----CTIDVHARDVVAKMIAQKVDNAQAFLWLSQLRHRWDD------------------ 1816
+ V RD+ + +V + F W+ QL++
Sbjct: 1570 LLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASS 1629
Query: 1817 ----EVKHCFANICDAQFLYSYEYLGNTPRLVITP--LTDRCYITLTQSLHLTMSGAPAG 1870
C+ ++ FLY+YEYLG PRL P L +R + L +L G G
Sbjct: 1630 EPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGTVLG 1687
Query: 1871 PAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVE 1930
P G GK L +ALG + + CS Q++ + N G Q GAW ++ +++
Sbjct: 1688 PNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPG 1747
Query: 1931 VLSVVAVQVKSI--------QDAIRD-------KKQWFS---FLGEEISLNPSVGIFITM 1972
+LS + ++ + Q+A R+ + Q F +S+ G + +
Sbjct: 1748 LLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVL 1807
Query: 1973 NPGYAGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKE 2032
A + +P NL L RP A+ +PD + E+ L+ G +A +A + + L +E
Sbjct: 1808 R---ALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERE 1864
Query: 2033 LLSKQDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIF-- 2090
L+S L +K +L + P+ Q RSL ++ P+F
Sbjct: 1865 LVS--GPLPCRLPLLKQILEDTIRTLNVTKEEPKCQ-KPRSLAAIEEAALLRS--PLFSI 1919
Query: 2091 ---------MGLIGDLFPALDVPRRRDPNF---EALVRKAIVDLKLQAEDNFVLKVVQLE 2138
GL+ LFP+ + + LV + + + L + + + QL
Sbjct: 1920 LNGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLS 1979
Query: 2139 ELLAVRHSVFVVGGAGTGKSQVLRSLHKTYQIMKR---------RPV-WTDLNPKAVTND 2188
+ L+ + ++G AG+GK+ SL K + +PV T L P ++
Sbjct: 1980 QALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITHLYPSGLSPQ 2039
Query: 2189 ELFGIINPATGEWKDGLFSSIMRELANITHDGPK-----------WILLDGDIDPMWIES 2237
E G + + W G+F ++R + G K WI+ DG + W++S
Sbjct: 2040 EFLGWLEGSC--WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDS 2097
Query: 2238 LNTVMDDNKVLTLASNERIPLNPTMKLLFEISHLRTATPATVSRAGILYINPADLGWNPP 2297
+ ++ + L+L S ++I P LL E++ +P V +++ + W
Sbjct: 2098 ITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCG-GEQTWQCI 2156
Query: 2298 VSSWIEKREIQTERANLTILFDKYLPTCLDTLRTRF------KKIIPIPEQ--------- 2342
+S+ + + + T+ ++ L RF ++ + Q
Sbjct: 2157 LSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAE 2216
Query: 2343 --SMVQMVCHLLECLLTTEDIPA--------------------------------DCPKE 2368
SM +++ LL+ L ++ A D P +
Sbjct: 2217 VTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDK 2276
Query: 2369 IYEHY-----FVFAAIWAFGGAMVQD--QLVDYRAEFSKWWLTEFKTVKFPSQGTIFDYY 2421
EH F+FA IW FG + + D S L+ + + P +FD +
Sbjct: 2277 CREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDSISRLSNYP--EPPPSALVFDLH 2334
Query: 2422 IDPETKKFEPWSKLVPQFEFDPEMPLQACLVHTSETIRVCYFMERLMARQRPVMLVGTAG 2481
+ PE P++ Q+ + +T R+ Y ++ L++ +PV+L G A
Sbjct: 2335 VSPEDGTLVPFT---GQYLSSHIKGTLGTFHPSIQTERLLYVVDLLLSGGQPVLLAGEAA 2391
Query: 2482 TGKSVLVGAKLASLDPEAYLVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLI 2541
TGKS V + P Y + F+ +L ++ + + L+
Sbjct: 2392 TGKSAFVEVLVEPHHPYIYSPIHPAFSSSHLRLLLSRGIQGQTQASPQPGHHQDSKPSLL 2451
Query: 2542 YFIDDMNMPEVDAYGTVQP-HTIIRQHLDYGHWYDRSKLSLKEI-TNVQYVSCMN-PTAG 2598
+ ++D+++ D + QP +RQ +D G Y S L L+ + V +++ + P
Sbjct: 2452 FLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQPTVNFLATVTVPGYC 2510
Query: 2599 SFTINPRLQRHFSVFVLSFPGADALSSIYSIILTQHLK-----LGNFPASLQKS--IPPL 2651
+ PRL R F+V L S + +L +H+ L FP+ ++ L
Sbjct: 2511 ERPLCPRLFRLFTVLALE-------SMTQATLLERHVPIIQAWLERFPSVERERALARGL 2563
Query: 2652 IDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIF------------------------- 2686
+ ++ + + F+P+ + HY F+L +++
Sbjct: 2564 VRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLLPNRTGSRGFVDYPNHQEHL 2623
Query: 2687 ---QGILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTF 2740
G+ + + + +T +++RL+LHE+ R + D++ ++ K+ V + F
Sbjct: 2624 RRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLLVVAQSVF 2680
Score = 114 bits (286), Expect = 2e-24
Identities = 178/801 (22%), Positives = 316/801 (39%), Gaps = 139/801 (17%)
Query: 2750 TQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHVCH 2809
+++PNLY + WE L + L + ++ L +HV
Sbjct: 2831 SETPNLYLE-------------RQWEKLEEQLATSAA---QLKLSPHLARCHSMAQHVAR 2874
Query: 2810 INRILESPRGNALLV-GVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASLC 2868
+ R+L PR + LL+ G G+G+ + LA+ I F + I D +
Sbjct: 2875 LVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCLRDAS--- 2931
Query: 2869 LKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKSQ 2928
AG+ + L+ D L + L SG P Y++ +++ I ++ E +
Sbjct: 2932 WHAGMLSQPVALLVPSG--VDLTTLHRLLALATSGSFPGQYTEADLDRIGEHLPRE--NL 2987
Query: 2929 GLVDNRENCWKFFIDRIRRQLKVTL-CFSPVGNKL---RVRSRKFPAIVNCT--AIHWFH 2982
G+ N + + + R +Q+ L F +G+K ++ S F ++ +I +
Sbjct: 2988 GVKQNIKK--EMVLQRFHQQVCSHLHLFFLIGDKQAHKQLPSTLFLRLLQLATASIDRYE 3045
Query: 2983 EWPQQALESVSLRFLQNTEGIE--------PTVKQSI---SKFMAFVHTSVNQTSQSYLS 3031
W Q AL V+ L+ + + P ++ SI +K MA +H S +
Sbjct: 3046 PWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIHLSATHYHEHLCP 3105
Query: 3032 NEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKCKTERLENGL------LKLHSTSAQVDD 3085
TPK+FL+F+ + L + ++K K +R++N L +K H T A +
Sbjct: 3106 ---ALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGTHANLI- 3161
Query: 3086 LKAKLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKD 3145
+L+Q+ +D+ K + + ++ + K + ++ LE + Q++
Sbjct: 3162 ---------FDLEQQLKDSGKSLSMF---QQQLEQSKLLYKQQ--------LEECRHQEN 3201
Query: 3146 CEEDLAKAEPALTAAQAA------------LNTLNKTNLTELKSFGSPPLAVSNVSAAVM 3193
E+LA+ AL A + A L+ L + E++S+ +PP +V V+ A+
Sbjct: 3202 LIENLARQRDALQAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMC 3261
Query: 3194 VLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLINFNKENIHENCLKAIRPYLQDPEFNPE 3253
L + W +AK + D F L+ F KE I ++ L + L+ P +
Sbjct: 3262 DLFH------HETGWASAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDA 3314
Query: 3254 FVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQALNKATADLTAAQEKLAAIKAKIAHL 3313
+ S AA L +W+ ++ + C P L + A LT Q +L + +
Sbjct: 3315 ALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQET 3374
Query: 3314 NENLAKLTARFEKATADKLKCQQEAEVTAVTISLAN-------RLVGGLASENVRWADAV 3366
E+ L E A A A T+S A + L + W +
Sbjct: 3375 LEHNLALAKMVEDAQASH-------NCVAKTLSQAQCGQYHKWPMKAALLTPMRAWTTQL 3427
Query: 3367 QNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTW----RPYLSQL--------- 3413
Q K + T+ GD LL +A I YLG F RQ LLD W R + L
Sbjct: 3428 QKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQAL 3486
Query: 3414 -----------KTPIPVTPA-LDPLRMLMDDADVAAWQNEGLPADRMS------VENATI 3455
K P+ T + L +L +++ W P + + + + T
Sbjct: 3487 KRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAKSAHLAGLLLRSPTH 3546
Query: 3456 LINCERWPLMVDPQLQGIKWI 3476
+C RWPL++DP + + W+
Sbjct: 3547 YSSC-RWPLLLDPSNEALIWL 3566
Score = 104 bits (260), Expect = 2e-21
Identities = 224/1082 (20%), Positives = 397/1082 (36%), Gaps = 147/1082 (13%)
Query: 3498 IEQALEAGAVVLIENLEESID-PVLGPLLGREVIKKGRFIKIGDKECEYNPKFRLILHTK 3556
+++A G VL+ N+E + L LL RE + + P F L L T
Sbjct: 3678 LQEAAACGLPVLLTNVELGLGCEELQWLLQREQLSPP----------QVQPGFCLYLSTT 3727
Query: 3557 LANPHYQP----ELQAQATLINFTVTRDGLEDQLLAAVVSMERPDLEQLKSDLTKQQNGF 3612
L+ + EL +++ + + LE+Q+L ++ E P+LE DL +
Sbjct: 3728 LSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDT 3787
Query: 3613 KITLKTLEDSLLSRLSSASGNFLGETVLVENLEITKQTAAEVEKKVQEAKVTEVKINEAR 3672
++ E+ LL+ L + + N+ + ++ +E + +++
Sbjct: 3788 CKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLW 3847
Query: 3673 EHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAFSIVFQKAVERAAP-----DESLRERV 3727
YRP + ++ L + P++ S + + V ++A++ P E L +
Sbjct: 3848 APYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHL 3907
Query: 3728 ANLIDSITFSVYQYTIR--GLFECDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTG 3785
L +T + T+ GL + + L L L+ A EL+ L P
Sbjct: 3908 LQLRAHLTRQLLGSTVTALGLTQVPLVGALGALA----LLQATGKASELERLALWPGLAA 3963
Query: 3786 TASPVE-----------FLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKKFVESECPE 3834
+ S V +L +AW ++L + F L + G + +W+ ++
Sbjct: 3964 SPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTV 4023
Query: 3835 KEKLPQEWKNKTAL-QRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDFAT----- 3888
P +L Q+L + R +RP+ + AL DF LG R LD T
Sbjct: 4024 LGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLG------RPLDENTYAPTM 4077
Query: 3889 SFEESGPATPMFFILSPG------VDPLKDVESQGRKLGYTFNNQNFHNVSLGQ---GQE 3939
F+ S PM +L P + PL ++ K Y + ++LG
Sbjct: 4078 PFKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAK--YQQGQKQLQVIALGSEAWDPV 4135
Query: 3940 VVAEAALDLAAKKGHWVILQNIHLVAKWLSTL-------------------EKKLEEHSE 3980
V + L A +GHW++L N HL+ W L E+ L++
Sbjct: 4136 SVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPES 4195
Query: 3981 NS----HPEFRVFMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQD 4036
+ H +FR+++ P+ +P + ++S+ + N L + D
Sbjct: 4196 RNVSTVHRDFRLWLIV---PAESSASLPAVLTQHSMPV--------FWNQSLELGHVLID 4244
Query: 4037 TLEMCSRETEFKSILFAL--CYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFL 4094
++E+ + + AL H ++ R+ +G + ++ LT V + L
Sbjct: 4245 SVELAQQVLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQVTLT-QVLQTQDQL 4303
Query: 4095 EANAKVPYDDLRYLFGEIMYGGHITDDWDRR----LCRTYL----GEFIRPEMLEGELSL 4146
A+ P ++ L + YGG + D DR L + L G +++P + L+
Sbjct: 4304 WASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLAT 4363
Query: 4147 APGFPLPGNMDYNGYHQYIDAELP-PESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQP- 4204
P +D + LP P P L GL + L + S L + P
Sbjct: 4364 LMPLPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPV 4423
Query: 4205 ------RDSQARDGAGATREEKVKALLEEILERVT-----DEFNIPELMAKVEERTPYIV 4253
R +Q + R +V LE + + +T DE + P + R P
Sbjct: 4424 WVPESRRGAQLAERRLRQRLVQVNRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEG 4483
Query: 4254 VAFQECGRMNILTREIQRSLRELELGLKGELTMTSHM-ENLQNALYFDMVPESWARRAYP 4312
V E ++ L +QR L L LKG S + +AL+ +P W A
Sbjct: 4484 VLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPA 4543
Query: 4313 STAGLAAWFPDLLNRIKELEAWTG-----DFTMPSTVW-LTGFFNPQSFLTAI-----MQ 4361
W L R + L + G +P V+ L+ F +P+ L A+ +
Sbjct: 4544 GPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALD 4603
Query: 4362 STARKNEWPLDQMALQCDMTKKNREEFRSP-------------PREGAYIHGLFMEGACW 4408
+ +P + ++ + K E +P P G + GL + A W
Sbjct: 4604 QNVPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEW 4663
Query: 4409 DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQ----DCRSVYSCPVYKTSQRGPTYVWTF 4464
D AG + ++ +P PV P +VYSCPVY G + +
Sbjct: 4664 DPIAGALQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVYMGGPLGTAKLQSR 4723
Query: 4465 NL 4466
N+
Sbjct: 4724 NI 4725
>gi|4502395 beclin 1 [Homo sapiens]
Length = 450
Score = 47.0 bits (110), Expect = 4e-04
Identities = 27/84 (32%), Positives = 45/84 (53%)
Query: 3089 KLAAQEVELKQKNEDADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEE 3148
+LA +E L Q+ ED +K ++V +KV E D+EE + E K++Q + ++
Sbjct: 186 ELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDD 245
Query: 3149 DLAKAEPALTAAQAALNTLNKTNL 3172
+L E + AQ L+ L KTN+
Sbjct: 246 ELKSVENQMRYAQTQLDKLKKTNV 269
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 46.2 bits (108), Expect = 7e-04
Identities = 113/489 (23%), Positives = 193/489 (39%), Gaps = 54/489 (11%)
Query: 1055 LSQFKVQIDSYET-LYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLLFKQHLVD 1113
+ Q K ++ E+ L +LE + + K I K SL +R ++L Q VD
Sbjct: 436 IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAIL--QTEVD 493
Query: 1114 HVTHSLANLDAFIKKSESGLLKKVE-KGDFQGLVEIMGHLMAVKERQSNTDEMFEPLKQT 1172
+ L ++F+ K L E KG G + M ++ VKER+ N L++
Sbjct: 494 ALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINV------LQKK 547
Query: 1173 IELLKTYEQELPETVFKQLEELPEKWNNIKKVAITVKQQVAPLQANEVTLLRQRCTAFDA 1232
IE L QE KQL L ++ +++ + +A L+ E ++R
Sbjct: 548 IENL----QEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLE--EALSEKERIIERLK 601
Query: 1233 EQQQ--FWEQFHKEAPFRFDSIHPHQMLDARHIEIQQMESTMASISESA-SLFEVNVPDY 1289
EQ++ E+ + FR ++ + ++A E+ + ES++ + E A SL +
Sbjct: 602 EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRD 661
Query: 1290 KQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKE 1349
+L+ + Q KE + H N+E +FA I+ LDKE
Sbjct: 662 SKLKSLEIAIEQKKEECSKLEAQLKKAH----------NIEDDSRMNPEFADQIKQLDKE 711
Query: 1350 VRAW-DAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVSFTMDQDTTLAHL 1408
+ D ++ V L L+ V +N +++ +L T + DQ+ +A+L
Sbjct: 712 ASYYRDECGKAQAEVDRLLEILKEVENEKND--KDKKIAELESLT-LRHMKDQNKKVANL 768
Query: 1409 LQLQLHHYE------DEVRGIVDKAAKEM----------GMEKTLKELQTTWAGMEFQYE 1452
Q + +EVR D A +EKT +EL T A + +
Sbjct: 769 KHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQ 828
Query: 1453 PHPRTNVPL----LCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGWQKKLSTVDAV 1508
L + + L E+LE Q L + K L E+S KK T + V
Sbjct: 829 SLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSA-SKKKKTQEEV 887
Query: 1509 ISIWFEVQR 1517
+++ E R
Sbjct: 888 MALKREKDR 896
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 43.9 bits (102), Expect = 0.004
Identities = 69/311 (22%), Positives = 137/311 (44%), Gaps = 61/311 (19%)
Query: 1147 EIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAI 1206
E++ + ++ER++ +E +++ +E + +Q L + K+L E + +
Sbjct: 105 ELLTRIRQLQEREAGAEEK---MQEQLERNRQCQQNL-DAASKRLREKEDSLAQAGETIN 160
Query: 1207 TVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQF---HK---EAPFRFDSIHPHQMLDA 1260
+K +++ LQ + V R ++E+Q+ EQ HK EA + + Q A
Sbjct: 161 ALKGRISELQWS-VMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARA 219
Query: 1261 RHIE-IQQMESTMASISESASLFE------VNVPDY-KQLRQCRKEVCQLKELWDTIGMV 1312
H + I+ +E ++ + A++ + V +P ++L+Q R+E L+E+ +T G++
Sbjct: 220 DHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLL 279
Query: 1313 TSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRA 1372
ELE Q R L ++ + + GLE L + R
Sbjct: 280 QE------------------ELEGLQ-----RKLGRQEKMQETLVGLE------LENERL 310
Query: 1373 VAELQNPAIRERHWRQLMQATGVSFTMDQDTT--LAHLLQLQLHHYEDEVRGIVDKAAKE 1430
+A+LQ+ W +L Q G+S +D + + L Q +L +D+ + A
Sbjct: 311 LAKLQS-------WERLDQTMGLSIRTPEDLSRFVVELQQREL-ALKDKNSAVTSSA--- 359
Query: 1431 MGMEKTLKELQ 1441
G+EK ++LQ
Sbjct: 360 RGLEKARQQLQ 370
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 43.9 bits (102), Expect = 0.004
Identities = 69/311 (22%), Positives = 137/311 (44%), Gaps = 61/311 (19%)
Query: 1147 EIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAI 1206
E++ + ++ER++ +E +++ +E + +Q L + K+L E + +
Sbjct: 105 ELLTRIRQLQEREAGAEEK---MQEQLERNRQCQQNL-DAASKRLREKEDSLAQAGETIN 160
Query: 1207 TVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQF---HK---EAPFRFDSIHPHQMLDA 1260
+K +++ LQ + V R ++E+Q+ EQ HK EA + + Q A
Sbjct: 161 ALKGRISELQWS-VMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARA 219
Query: 1261 RHIE-IQQMESTMASISESASLFE------VNVPDY-KQLRQCRKEVCQLKELWDTIGMV 1312
H + I+ +E ++ + A++ + V +P ++L+Q R+E L+E+ +T G++
Sbjct: 220 DHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLL 279
Query: 1313 TSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRA 1372
ELE Q R L ++ + + GLE L + R
Sbjct: 280 QE------------------ELEGLQ-----RKLGRQEKMQETLVGLE------LENERL 310
Query: 1373 VAELQNPAIRERHWRQLMQATGVSFTMDQDTT--LAHLLQLQLHHYEDEVRGIVDKAAKE 1430
+A+LQ+ W +L Q G+S +D + + L Q +L +D+ + A
Sbjct: 311 LAKLQS-------WERLDQTMGLSIRTPEDLSRFVVELQQREL-ALKDKNSAVTSSA--- 359
Query: 1431 MGMEKTLKELQ 1441
G+EK ++LQ
Sbjct: 360 RGLEKARQQLQ 370
>gi|62243332 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 43.9 bits (102), Expect = 0.004
Identities = 69/311 (22%), Positives = 137/311 (44%), Gaps = 61/311 (19%)
Query: 1147 EIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKKVAI 1206
E++ + ++ER++ +E +++ +E + +Q L + K+L E + +
Sbjct: 105 ELLTRIRQLQEREAGAEEK---MQEQLERNRQCQQNL-DAASKRLREKEDSLAQAGETIN 160
Query: 1207 TVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQF---HK---EAPFRFDSIHPHQMLDA 1260
+K +++ LQ + V R ++E+Q+ EQ HK EA + + Q A
Sbjct: 161 ALKGRISELQWS-VMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARA 219
Query: 1261 RHIE-IQQMESTMASISESASLFE------VNVPDY-KQLRQCRKEVCQLKELWDTIGMV 1312
H + I+ +E ++ + A++ + V +P ++L+Q R+E L+E+ +T G++
Sbjct: 220 DHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLL 279
Query: 1313 TSSIHAWETTPWRNINVEAMELECKQFARHIRNLDKEVRAWDAFTGLESTVWNTLSSLRA 1372
ELE Q R L ++ + + GLE L + R
Sbjct: 280 QE------------------ELEGLQ-----RKLGRQEKMQETLVGLE------LENERL 310
Query: 1373 VAELQNPAIRERHWRQLMQATGVSFTMDQDTT--LAHLLQLQLHHYEDEVRGIVDKAAKE 1430
+A+LQ+ W +L Q G+S +D + + L Q +L +D+ + A
Sbjct: 311 LAKLQS-------WERLDQTMGLSIRTPEDLSRFVVELQQREL-ALKDKNSAVTSSA--- 359
Query: 1431 MGMEKTLKELQ 1441
G+EK ++LQ
Sbjct: 360 RGLEKARQQLQ 370
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.5 bits (101), Expect = 0.005
Identities = 88/431 (20%), Positives = 182/431 (42%), Gaps = 73/431 (16%)
Query: 1064 SYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLL--FKQHLVDHVTHSLAN 1121
S+ +L EE+ ++ I DG +K +A LL + + + KQ + + + N
Sbjct: 791 SFASLVEELKKV--IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE-IKALKEEIGN 847
Query: 1122 LDAFIKKSESGLLKKVEKGD--FQGLVEIMGHLMAVKERQ----SNTDEMFEPLKQTIEL 1175
+ K + + KV++ +G E M + AV E + +NT + + L++ E
Sbjct: 848 VQ-LEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 906
Query: 1176 LKTYEQELPE---------TVFKQLE-ELPEKWNNIKKVAITVKQQVAPLQANEVTL--L 1223
LK + QE+ + + F++LE L EK N +K++ +K++ + L + L +
Sbjct: 907 LKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDV 966
Query: 1224 RQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQ----MLDARHIEIQQMESTMASISESA 1279
+ F ++ +Q +Q +++A S PH+ ++ R EI + + + S+ ++
Sbjct: 967 QDENKLFKSQIEQLKQQNYQQA----SSFPPHEELLKVISEREKEISGLWNELDSLKDAV 1022
Query: 1280 SLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQF 1339
E LR+ E ++ L T M+ ++ +T+ R VEA+ELE K+
Sbjct: 1023 ---EHQRKKNNDLREKNWEA--MEALASTEKMLQDKVN--KTSKERQQQVEAVELEAKEV 1075
Query: 1340 ARHI---RNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVS 1396
+ + ++ + + G E ++ E++ +
Sbjct: 1076 LKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVK----------------VLE 1119
Query: 1397 FTMDQDTTLAHLLQLQLHHYED---EVRGIVDKAAKEMGME------------KTLKELQ 1441
+ + + LLQL+ Y+ E GI+ K + + E KT+K++Q
Sbjct: 1120 HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQ 1179
Query: 1442 TTWAGMEFQYE 1452
+++ E + E
Sbjct: 1180 SSFTSSEQELE 1190
Score = 36.2 bits (82), Expect = 0.75
Identities = 88/428 (20%), Positives = 166/428 (38%), Gaps = 59/428 (13%)
Query: 472 GNALSQQVQQMH--EEFQEMYRLLSGSSSDCLYLQST--DFENDVSEFNQKVEDLDRRLG 527
GN ++ QQ+ + QE+ LL G +++ + E D++ + ++DL
Sbjct: 846 GNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENE 905
Query: 528 TIFIQAFDDAPGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNK---DLDAVRMI 584
++ + A +H K A E +V ++ ++ L M + DL + +
Sbjct: 906 SLKAHVQEVA---QHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQL 962
Query: 585 YSQHVQEEAELGFSPVHK----------NMPTVAGGLRWAQELRQRIQGPFSNFGRITHP 634
Q VQ+E +L S + + + P L+ E + I G ++ +
Sbjct: 963 L-QDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDA 1021
Query: 635 CM-ESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKEIT 693
+ + +++K + + L E L + +T E+ Q + L E KE+
Sbjct: 1022 VEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVEL-----EAKEVL 1076
Query: 694 INFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTL 753
P+ +SV +SY E H E A + + V LE ++ M TL
Sbjct: 1077 KKLFPK-VSVPSNLSY---GEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADE-MHTL 1131
Query: 754 LEVEFP-----LVEEE--LQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQK 806
L++E L E E LQ + + E K + + ++ SS EQ +++
Sbjct: 1132 LQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191
Query: 807 TKDNVEEIQNIMK-----------------TWVTPIFKTKDGKRESLLSLDDRHD---RM 846
+ ++I+N+ + T+VT + + KD E LDD + R
Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ 1251
Query: 847 EKYYNLIK 854
+ NL+K
Sbjct: 1252 NEELNLLK 1259
Score = 35.8 bits (81), Expect = 0.98
Identities = 23/103 (22%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 3043 SFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNE 3102
SF + + ++H ++K E LE LLK+ + V DLK ++ A + E+
Sbjct: 791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 3103 DADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKD 3145
+ + + + T KV + + +E+++ + +++K+KD
Sbjct: 851 EKAQQLSI----TSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.5 bits (101), Expect = 0.005
Identities = 88/431 (20%), Positives = 182/431 (42%), Gaps = 73/431 (16%)
Query: 1064 SYETLYEEVCRLEPIKVFDGWMKIDIRPFKASLLNIIKRWSLL--FKQHLVDHVTHSLAN 1121
S+ +L EE+ ++ I DG +K +A LL + + + KQ + + + N
Sbjct: 791 SFASLVEELKKV--IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE-IKALKEEIGN 847
Query: 1122 LDAFIKKSESGLLKKVEKGD--FQGLVEIMGHLMAVKERQ----SNTDEMFEPLKQTIEL 1175
+ K + + KV++ +G E M + AV E + +NT + + L++ E
Sbjct: 848 VQ-LEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 906
Query: 1176 LKTYEQELPE---------TVFKQLE-ELPEKWNNIKKVAITVKQQVAPLQANEVTL--L 1223
LK + QE+ + + F++LE L EK N +K++ +K++ + L + L +
Sbjct: 907 LKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDV 966
Query: 1224 RQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQ----MLDARHIEIQQMESTMASISESA 1279
+ F ++ +Q +Q +++A S PH+ ++ R EI + + + S+ ++
Sbjct: 967 QDENKLFKSQIEQLKQQNYQQA----SSFPPHEELLKVISEREKEISGLWNELDSLKDAV 1022
Query: 1280 SLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNINVEAMELECKQF 1339
E LR+ E ++ L T M+ ++ +T+ R VEA+ELE K+
Sbjct: 1023 ---EHQRKKNNDLREKNWEA--MEALASTEKMLQDKVN--KTSKERQQQVEAVELEAKEV 1075
Query: 1340 ARHI---RNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERHWRQLMQATGVS 1396
+ + ++ + + G E ++ E++ +
Sbjct: 1076 LKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVK----------------VLE 1119
Query: 1397 FTMDQDTTLAHLLQLQLHHYED---EVRGIVDKAAKEMGME------------KTLKELQ 1441
+ + + LLQL+ Y+ E GI+ K + + E KT+K++Q
Sbjct: 1120 HKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQ 1179
Query: 1442 TTWAGMEFQYE 1452
+++ E + E
Sbjct: 1180 SSFTSSEQELE 1190
Score = 36.2 bits (82), Expect = 0.75
Identities = 88/428 (20%), Positives = 166/428 (38%), Gaps = 59/428 (13%)
Query: 472 GNALSQQVQQMH--EEFQEMYRLLSGSSSDCLYLQST--DFENDVSEFNQKVEDLDRRLG 527
GN ++ QQ+ + QE+ LL G +++ + E D++ + ++DL
Sbjct: 846 GNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENE 905
Query: 528 TIFIQAFDDAPGLEHAFKLLDIAGNLLERPLVARDTSDKYLVLIQMFNK---DLDAVRMI 584
++ + A +H K A E +V ++ ++ L M + DL + +
Sbjct: 906 SLKAHVQEVA---QHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQL 962
Query: 585 YSQHVQEEAELGFSPVHK----------NMPTVAGGLRWAQELRQRIQGPFSNFGRITHP 634
Q VQ+E +L S + + + P L+ E + I G ++ +
Sbjct: 963 L-QDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDA 1021
Query: 635 CM-ESAEGKRMQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKEIT 693
+ + +++K + + L E L + +T E+ Q + L E KE+
Sbjct: 1022 VEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVEL-----EAKEVL 1076
Query: 694 INFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVANLELMANWYNKVMKTL 753
P+ +SV +SY E H E A + + V LE ++ M TL
Sbjct: 1077 KKLFPK-VSVPSNLSY---GEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADE-MHTL 1131
Query: 754 LEVEFP-----LVEEE--LQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQK 806
L++E L E E LQ + + E K + + ++ SS EQ +++
Sbjct: 1132 LQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191
Query: 807 TKDNVEEIQNIMK-----------------TWVTPIFKTKDGKRESLLSLDDRHD---RM 846
+ ++I+N+ + T+VT + + KD E LDD + R
Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQ 1251
Query: 847 EKYYNLIK 854
+ NL+K
Sbjct: 1252 NEELNLLK 1259
Score = 35.8 bits (81), Expect = 0.98
Identities = 23/103 (22%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 3043 SFLEFIRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNE 3102
SF + + ++H ++K E LE LLK+ + V DLK ++ A + E+
Sbjct: 791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 3103 DADKLIQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKD 3145
+ + + + T KV + + +E+++ + +++K+KD
Sbjct: 851 EKAQQLSI----TSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 43.5 bits (101), Expect = 0.005
Identities = 84/393 (21%), Positives = 157/393 (39%), Gaps = 29/393 (7%)
Query: 3005 PTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEFIRLYQSLLHRHRKELKC 3064
P+ S S +A +H+++++ + R Y + L +R S R+ L+
Sbjct: 511 PSPACSDSSTLALIHSALHKRQLQV--QDMRGRYEASQDLLGTLRKQLSDSESERRALEE 568
Query: 3065 KTERLEN---GLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKLIQVVGVETDKV--S 3119
+ +RL + G ++ H + + +++ +A E+ ++K+ A L QV + +++
Sbjct: 569 QLQRLRDKTDGAMQAHEDAQR--EVQRLRSANELLSREKSNLAHSL-QVAQQQAEELRQE 625
Query: 3120 REKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTLN------KTNLT 3173
REK A +EE + LE ++Q+D +D A+ L + L L L
Sbjct: 626 REKLQAAQEELRRQRDRLE--EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELV 683
Query: 3174 ELKSFGSPP------LAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLIN 3227
E++ S L A + A GRV + S + A + L L
Sbjct: 684 EVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSA 743
Query: 3228 FNKENIHENCLKAIRPYLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKRQ 3287
N E++ ++ L R Q E + A R E+ + E RQ
Sbjct: 744 LN-ESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQ 802
Query: 3288 ALNKATADLTAAQE----KLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAV 3343
L + AQE +L ++ + + L E LA+L+ + + + ++EA+
Sbjct: 803 GLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE 862
Query: 3344 TISLANRLVGGLASENVRWADAVQNFKQQERTL 3376
+ A R LA E+ A + +++ RTL
Sbjct: 863 ALERAAREKEALAKEHAGLAVQLVAAEREGRTL 895
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 42.7 bits (99), Expect = 0.008
Identities = 75/382 (19%), Positives = 164/382 (42%), Gaps = 66/382 (17%)
Query: 1109 QHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQGLVEIMGHLMAVKERQ----SNTDE 1164
+ L++ +AN + ++ S + +++++ +G E M + AV E + +NT +
Sbjct: 814 EELLEAELLKVANKEKTVQLSITSKVQELQNL-LKGKEEQMNTMKAVLEEKEKDLANTGK 872
Query: 1165 MFEPLKQTIELLKTYEQELPE---------TVFKQLE-ELPEKWNNIKKVAITVKQQVAP 1214
+ L++ E LK + QE+ + + F++LE L EK N +K++ +K++ +
Sbjct: 873 WLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESD 932
Query: 1215 LQANEVTL--LRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQ----MLDARHIEIQQM 1268
L + L ++ F ++ +Q +Q +++A S PH+ ++ R EI +
Sbjct: 933 LSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQA----SSFPPHEELLKVISEREKEISGL 988
Query: 1269 ESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTPWRNIN 1328
+ + S+ ++ E LR+ E ++ L T M+ ++ +T+ R
Sbjct: 989 WNELDSLKDAV---EHQRKKNNDLREKNWEA--MEALASTEKMLQDKVN--KTSKERQQQ 1041
Query: 1329 VEAMELECKQFARHI---RNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQNPAIRERH 1385
VEA+ELE K+ + + ++ + + G E ++ E++
Sbjct: 1042 VEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVK-------- 1093
Query: 1386 WRQLMQATGVSFTMDQDTTLAHLLQLQLHHYED---EVRGIVDKAAKEMGME-------- 1434
+ + + + LLQL+ Y+ E GI+ K + + E
Sbjct: 1094 --------VLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKV 1145
Query: 1435 ----KTLKELQTTWAGMEFQYE 1452
KT+K++Q+++ E + E
Sbjct: 1146 DESHKTIKQMQSSFTSSEQELE 1167
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 42.4 bits (98), Expect = 0.011
Identities = 99/449 (22%), Positives = 171/449 (38%), Gaps = 84/449 (18%)
Query: 383 LRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVRLDGF 442
L+++ EESQR LQ + E QD + +L E Q+V+ + + R D
Sbjct: 1414 LQADSEESQRALQQLKKKCQRLTAELQDTKLHL-----EGQQVRNHELEKKQ--RRFDSE 1466
Query: 443 LGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLY 502
L Q H E + L KL + E + A S + QQ+ E+
Sbjct: 1467 LSQAH--EEAQREKLQREKLQR-EKDMLLAEAFSLK-QQLEEK----------------- 1505
Query: 503 LQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFK-LLDIAGNLLERPLVAR 561
+ D++ F QKV L+ L I Q D L K L D+ + ++
Sbjct: 1506 ------DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ----E 1555
Query: 562 DTSDKYLVLIQMFNK-------DLDAVRMIYSQHVQ---EEAELGFSPVHKNMPTVAGGL 611
+ D+ IQM + +++ +R +S+ ++ EE E K + + L
Sbjct: 1556 EELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQL 1615
Query: 612 RWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLE-KYETRLYEDWCRTV 670
E +Q++ E E + D ++ + + E RL +D RT
Sbjct: 1616 EEEYEDKQKV-------------LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTK 1662
Query: 671 SEKSQYNLSQPLLKRD-PETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSR 729
+ + L LK P +EI QL + L+E + T AA +R
Sbjct: 1663 ALLADAQLMLDHLKNSAPSKREIA-----QLKNQLEESEF-----------TCAAAVKAR 1706
Query: 730 DFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLN---WKTEGI 786
+ +L L + K KT LE + ++ E I RL +E +N K +
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKA-KTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAA 1765
Query: 787 CDYVTEITSSIHDLEQRIQKTKDNVEEIQ 815
+ + I+DL+ ++++ +E+Q
Sbjct: 1766 VAQASRDLAQINDLQAQLEEANKEKQELQ 1794
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 42.4 bits (98), Expect = 0.011
Identities = 99/449 (22%), Positives = 171/449 (38%), Gaps = 84/449 (18%)
Query: 383 LRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQEVKEWDFQSSLVFVRLDGF 442
L+++ EESQR LQ + E QD + +L E Q+V+ + + R D
Sbjct: 1414 LQADSEESQRALQQLKKKCQRLTAELQDTKLHL-----EGQQVRNHELEKKQ--RRFDSE 1466
Query: 443 LGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLY 502
L Q H E + L KL + E + A S + QQ+ E+
Sbjct: 1467 LSQAH--EEAQREKLQREKLQR-EKDMLLAEAFSLK-QQLEEK----------------- 1505
Query: 503 LQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAFK-LLDIAGNLLERPLVAR 561
+ D++ F QKV L+ L I Q D L K L D+ + ++
Sbjct: 1506 ------DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ----E 1555
Query: 562 DTSDKYLVLIQMFNK-------DLDAVRMIYSQHVQ---EEAELGFSPVHKNMPTVAGGL 611
+ D+ IQM + +++ +R +S+ ++ EE E K + + L
Sbjct: 1556 EELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQL 1615
Query: 612 RWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLE-KYETRLYEDWCRTV 670
E +Q++ E E + D ++ + + E RL +D RT
Sbjct: 1616 EEEYEDKQKV-------------LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTK 1662
Query: 671 SEKSQYNLSQPLLKRD-PETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSR 729
+ + L LK P +EI QL + L+E + T AA +R
Sbjct: 1663 ALLADAQLMLDHLKNSAPSKREIA-----QLKNQLEESEF-----------TCAAAVKAR 1706
Query: 730 DFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLN---WKTEGI 786
+ +L L + K KT LE + ++ E I RL +E +N K +
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKA-KTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAA 1765
Query: 787 CDYVTEITSSIHDLEQRIQKTKDNVEEIQ 815
+ + I+DL+ ++++ +E+Q
Sbjct: 1766 VAQASRDLAQINDLQAQLEEANKEKQELQ 1794
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 164,985,184
Number of Sequences: 37866
Number of extensions: 7440954
Number of successful extensions: 23101
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 21487
Number of HSP's gapped (non-prelim): 1414
length of query: 4486
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4363
effective length of database: 13,590,000
effective search space: 59293170000
effective search space used: 59293170000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.