BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapiens] (375 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 747 0.0 gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 747 0.0 gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 747 0.0 gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 445 e-125 gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 346 2e-95 gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 346 2e-95 gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 346 2e-95 gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 346 2e-95 gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 346 2e-95 gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 285 4e-77 gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 281 9e-76 gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 274 1e-73 gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 272 3e-73 gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 272 3e-73 gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 272 3e-73 gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 266 2e-71 gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 266 2e-71 gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 258 8e-69 gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 256 3e-68 gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 256 3e-68 gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 253 2e-67 gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 252 3e-67 gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 242 3e-64 gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 238 5e-63 gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 237 1e-62 gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 227 2e-59 gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 216 2e-56 gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 216 2e-56 gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 216 2e-56 gi|71061468 centromere protein E [Homo sapiens] 32 1.2 >gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 747 bits (1929), Expect = 0.0 Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID Sbjct: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60 Query: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF Sbjct: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120 Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180 Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240 Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300 Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360 Query: 361 RERELRTLLLQQSNV 375 RERELRTLLLQQSNV Sbjct: 361 RERELRTLLLQQSNV 375 >gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 747 bits (1929), Expect = 0.0 Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID Sbjct: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60 Query: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF Sbjct: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120 Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180 Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240 Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300 Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360 Query: 361 RERELRTLLLQQSNV 375 RERELRTLLLQQSNV Sbjct: 361 RERELRTLLLQQSNV 375 >gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 747 bits (1929), Expect = 0.0 Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID Sbjct: 1 MDAIHIGMSSTPLVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVID 60 Query: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF Sbjct: 61 MKWRYKLTLFAATFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLF 120 Query: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF Sbjct: 121 SLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKF 180 Query: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD Sbjct: 181 SHCAVITKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD 240 Query: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY Sbjct: 241 SSSESPFLILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSY 300 Query: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ Sbjct: 301 IPEEIYWGFEFVPVVSLSKNGKYVADFSQFEQIRKSPDCTFYCADSEKQQLEEKYRQEDQ 360 Query: 361 RERELRTLLLQQSNV 375 RERELRTLLLQQSNV Sbjct: 361 RERELRTLLLQQSNV 375 >gi|25121966 potassium inwardly-rectifying channel, subfamily J, member 10 [Homo sapiens] Length = 379 Score = 445 bits (1144), Expect = e-125 Identities = 231/363 (63%), Positives = 283/363 (77%), Gaps = 11/363 (3%) Query: 19 GAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTW 78 G G++ R RV++K G SNVR++ + LYL+DLWTT IDM+WRYKL LF+ATF TW Sbjct: 22 GPGIR--RRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTW 79 Query: 79 FLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEE 138 FLFGV++Y +A HGDL +P +NHTPC+++V +LTGAFLFSLESQTTIGYG R I+EE Sbjct: 80 FLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEE 139 Query: 139 CPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQ 198 CP AI LL+AQLV+TT++EIFITGTFLAKIARPKKRAETI+FS AV+ NGK CL+I+ Sbjct: 140 CPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIR 199 Query: 199 VANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVL 258 VANMRKSLLI CQ++GKLLQTH TKEGE I LNQ V F VD++S+SPFLILP+TFYHV+ Sbjct: 200 VANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVV 259 Query: 259 DETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLS 318 DETSPL+DL P E +FELV++L+ TVESTSA CQ RTSY+PEEI WG+EF P +SLS Sbjct: 260 DETSPLKDL-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLS 318 Query: 319 KNGKYVADFSQFEQIRK--SP----DCTFYCADSEKQQLEEKYRQEDQRERELRTLLLQQ 372 +GKY+ADFS F+Q+ K SP D T D EK +LEE R +Q E+E L ++ Sbjct: 319 ASGKYIADFSLFDQVVKVASPSGLRDSTVRYGDPEKLKLEESLR--EQAEKEGSALSVRI 376 Query: 373 SNV 375 SNV Sbjct: 377 SNV 379 >gi|24497471 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 346 bits (887), Expect = 2e-95 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%) Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79 G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74 Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139 FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134 Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199 AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194 Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259 AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254 Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319 SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314 Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348 GKY DF F + ++P C C +EK Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344 >gi|24497467 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 346 bits (887), Expect = 2e-95 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%) Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79 G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74 Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139 FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134 Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199 AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194 Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259 AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254 Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319 SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314 Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348 GKY DF F + ++P C C +EK Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344 >gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo sapiens] Length = 391 Score = 346 bits (887), Expect = 2e-95 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%) Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79 G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF Sbjct: 34 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 93 Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139 FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C Sbjct: 94 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 153 Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199 AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V Sbjct: 154 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 213 Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259 AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D Sbjct: 214 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 273 Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319 SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K Sbjct: 274 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 333 Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348 GKY DF F + ++P C C +EK Sbjct: 334 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 363 >gi|148539892 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 346 bits (887), Expect = 2e-95 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%) Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79 G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74 Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139 FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134 Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199 AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194 Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259 AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254 Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319 SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314 Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348 GKY DF F + ++P C C +EK Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344 >gi|24497473 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 346 bits (887), Expect = 2e-95 Identities = 168/331 (50%), Positives = 230/331 (69%), Gaps = 4/331 (1%) Query: 21 GLKANRPRVMSKSGHSNVRIDKVDG-IYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWF 79 G R R++SK G N+ V+ ++ D+WTTV+D+KWRYK+T+F F+ +WF Sbjct: 15 GHSRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWF 74 Query: 80 LFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEEC 139 FG+++YA+A+IH DL P +NHTPC+ ++ LT AFLFSLE+Q TIGYG R +TE+C Sbjct: 75 FFGLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134 Query: 140 PHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQV 199 AIFLL+ Q ++ +I F+ G LAKI+RPKKRA+TI FS AVI+K+ GKLCL+I+V Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194 Query: 200 ANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLD 259 AN+RKSLLI + GKLL+T VT EGE I+L+Q + F VD+ +E+ F I P+T YHV+D Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVID 254 Query: 260 ETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSK 319 SP + + L +++FELVV L+ TVESTSA CQ RTSY+PEE+ WG+ F P+VS +K Sbjct: 255 HNSPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTK 314 Query: 320 NGKYVADFSQFEQI--RKSPDCTFYCADSEK 348 GKY DF F + ++P C C +EK Sbjct: 315 EGKYRVDFHNFSKTVEVETPHCAM-CLYNEK 344 >gi|23110982 potassium inwardly-rectifying channel, subfamily J, member 12 [Homo sapiens] Length = 433 Score = 285 bits (730), Expect = 4e-77 Identities = 142/333 (42%), Positives = 216/333 (64%), Gaps = 11/333 (3%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFG+I+ Sbjct: 43 RNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIF 102 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IA HGDLEP E TPC+M+V AFLFS+E+QTTIGYG+R +TEECP A+F+ Sbjct: 103 WVIAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 +VAQ ++ +I+ F+ G +AK+ARPKKRA+T+ FSH AV+ ++GKLCL+ +V N+RKS Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265 +++ + +L++ VT+EGE I L+Q + D + FL+ P+T H +DE SPL Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281 Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325 ++ Q+L+ +FE+VV+L VE+T+ Q+R+SY+ EI WG F PV+ KN +Y Sbjct: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340 Query: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355 D+S F ++ +P C S K +E K+ Sbjct: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367 >gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis susceptibility ion channel [Homo sapiens] Length = 433 Score = 281 bits (718), Expect = 9e-76 Identities = 142/333 (42%), Positives = 214/333 (64%), Gaps = 11/333 (3%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI+ Sbjct: 43 RNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IA HGDLEP E TPC+M+V AFLFS+E+QTTIGYG+R +TEEC A+F+ Sbjct: 103 WVIAVAHGDLEPAEG-HGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAVFM 161 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 +VAQ ++ +I+ F+ G +AK+ARPKKRA T+ FSH AV+ ++GKLCL+ +V N+RKS Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265 +++ + +L++ VT+EGE I L+Q + D + FL+ P+T H +DE SPL Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLF 281 Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325 ++ Q+L+ +FE+VV+L VE+T+ Q+R+SY+ EI WG F PV+ KN +Y Sbjct: 282 GISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKN-QYKI 340 Query: 326 DFSQFE---QIRKSPDCTFYCADSEKQQLEEKY 355 D+S F ++ +P C S K +E K+ Sbjct: 341 DYSHFHKTYEVPSTPRC------SAKDLVENKF 367 >gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] Length = 427 Score = 274 bits (700), Expect = 1e-73 Identities = 139/330 (42%), Positives = 212/330 (64%), Gaps = 7/330 (2%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R + K GH NV+ V YL D++TT +D++WR+ L +F FV++W FG ++ Sbjct: 44 RSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVF 103 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IA +HGDL+ + C+ +V+S T AFLFS+E+QTTIGYG R +T+ECP A+F+ Sbjct: 104 WLIALLHGDLDASK---EGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 +V Q ++ +I+ FI G +AK+A+PKKR ET+ FSH AVI ++GKLCL+ +V N+RKS Sbjct: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265 L++ + +LL++ +T EGE I L+Q + DS + FL+ P+T H +DE SPL Sbjct: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280 Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325 DL+ Q++ +FE+VV+L VE+T+ Q R+SY+ EI WG + PV+ K+ Y Sbjct: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKH-YYKV 339 Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEKY 355 D+S+F + + P+ T C S + E+KY Sbjct: 340 DYSRFHKTYEVPN-TPLC--SARDLAEKKY 366 >gi|239757993 PREDICTED: similar to inward rectifying K+ channel negative regulator Kir2.2v isoform 1 [Homo sapiens] Length = 432 Score = 272 bits (696), Expect = 3e-73 Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%) Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87 R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++ Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104 Query: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147 IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V Sbjct: 105 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 163 Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207 AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS + Sbjct: 164 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 223 Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267 ++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL + Sbjct: 224 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 283 Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327 + Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+ Sbjct: 284 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 341 Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355 F ++ +P C S K +E K+ Sbjct: 342 LHFHKTYEVPSTPRC------SAKDLVENKF 366 >gi|239757991 PREDICTED: similar to inward rectifying K+ channel negative regulator Kir2.2v isoform 2 [Homo sapiens] Length = 534 Score = 272 bits (696), Expect = 3e-73 Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%) Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87 R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++ Sbjct: 147 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 206 Query: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147 IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V Sbjct: 207 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 265 Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207 AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS + Sbjct: 266 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 325 Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267 ++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL + Sbjct: 326 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 385 Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327 + Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+ Sbjct: 386 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 443 Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355 F ++ +P C S K +E K+ Sbjct: 444 LHFHKTYEVPSTPRC------SAKDLVENKF 468 >gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo sapiens] Length = 432 Score = 272 bits (696), Expect = 3e-73 Identities = 135/331 (40%), Positives = 208/331 (62%), Gaps = 12/331 (3%) Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87 R + K+G N+ +D YL D++TT +D++WRY L +F+ F+ +W LFGVI++ Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104 Query: 88 IAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLV 147 IA HGDLEP E TPC+M+V AFLFS+++Q TI YG+R +TEECP A+F++V Sbjct: 105 IAVAHGDLEPAEG-RGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVV 163 Query: 148 AQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKSLL 207 AQ ++ +I F+ G +AK+ RPKKRA+T+ FSH AV+ ++GKLC + +V N+RKS + Sbjct: 164 AQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHI 223 Query: 208 IQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLRDL 267 ++ + +L++ VTKEGE I L+Q + D + FL+ P+T H +DE SPL + Sbjct: 224 VEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASPLFGI 283 Query: 268 TPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADF 327 + Q+L+ +FE+V++L VE+T+ Q+R+SY+ EI WG F PV L + +Y D+ Sbjct: 284 SRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPV--LFEKNQYKIDY 341 Query: 328 SQFE---QIRKSPDCTFYCADSEKQQLEEKY 355 F ++ +P C S K +E K+ Sbjct: 342 LHFHKTYEVPSTPRC------SAKDLVENKF 366 >gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] Length = 445 Score = 266 bits (681), Expect = 2e-71 Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%) Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 + R R + K+G NV + Y+ D++TT +D +WRY L +F+A F+++W FG Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74 Query: 83 VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127 ++++ IAF HGDLE PG P + PCIM V+ GAFLFS+E+QTT Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134 Query: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187 IGYG R +TEECP A+ +V Q ++ +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+ Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194 Query: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247 ++GKLCL+ +V N+RKS +++ + +L++ ++T+EGE + L+Q + D + F Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254 Query: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307 L+ P+ H +DE SPL + + L+ ++FE+VV+L VE+T+ Q+R+SY+ EI W Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314 Query: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340 G F PVV + Y D+S+F ++ +P C+ Sbjct: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349 >gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] Length = 445 Score = 266 bits (681), Expect = 2e-71 Identities = 134/336 (39%), Positives = 210/336 (62%), Gaps = 19/336 (5%) Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 + R R + K+G NV + Y+ D++TT +D +WRY L +F+A F+++W FG Sbjct: 15 RKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFG 74 Query: 83 VIYYAIAFIHGDLE--PGEPISNHT-------------PCIMKVDSLTGAFLFSLESQTT 127 ++++ IAF HGDLE PG P + PCIM V+ GAFLFS+E+QTT Sbjct: 75 LLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTT 134 Query: 128 IGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVIT 187 IGYG R +TEECP A+ +V Q ++ +I+ F+ GT +AK+ARPKKRA+T+ FSH AVI+ Sbjct: 135 IGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIS 194 Query: 188 KQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPF 247 ++GKLCL+ +V N+RKS +++ + +L++ ++T+EGE + L+Q + D + F Sbjct: 195 VRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDRIF 254 Query: 248 LILPMTFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYW 307 L+ P+ H +DE SPL + + L+ ++FE+VV+L VE+T+ Q+R+SY+ EI W Sbjct: 255 LVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEILW 314 Query: 308 GFEFVPVVSLSKNGKYVADFSQFE---QIRKSPDCT 340 G F PVV + Y D+S+F ++ +P C+ Sbjct: 315 GHRFEPVV-FEEKSHYKVDYSRFHKTYEVAGTPCCS 349 >gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] Length = 419 Score = 258 bits (658), Expect = 8e-69 Identities = 129/320 (40%), Positives = 198/320 (61%), Gaps = 7/320 (2%) Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 K R R M KSG NV V Y YL DL+TT++D+KWR+ L +F + +TW FG Sbjct: 47 KKPRQRYMEKSGKCNVHHGNVQETYR-YLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105 Query: 83 VIYYAIAFIHGDLEP-GEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPH 141 I++ IA+I GDL+ G+ PC+ + AFLFS+E++TTIGYG R ITE+CP Sbjct: 106 FIWWLIAYIRGDLDHVGD--QEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163 Query: 142 AIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVAN 201 I LL+ Q ++ +++ F+ G KI++PKKRAET+ FS+ AVI+ ++ KLCL+ +V + Sbjct: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223 Query: 202 MRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDET 261 +R S +++ + KL+++ TKEGE I LNQ + D+ + FL+ P+ H +++ Sbjct: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283 Query: 262 SPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321 SP +++ L ++EFE+VV+L VE+T CQ+R+SY+ E+ WG F PV++L K G Sbjct: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEK-G 342 Query: 322 KYVADFSQFEQI--RKSPDC 339 Y D++ F +P C Sbjct: 343 FYEVDYNTFHDTYETNTPSC 362 >gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] Length = 436 Score = 256 bits (653), Expect = 3e-68 Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R + K GH NVR + G YL DL+TT +D++WR+ LF+ +F+ +W LFG+ + Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IA +HGDL P + PC V S AFLF+LE+QT+IGYGVRS+TEECP A+ Sbjct: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 +V Q + +++ F+ G +AK+A+PKKR ET+ FS AV+ ++ +LCL+ +V N+R+S Sbjct: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265 L++ + +LLQ VT EGE I L+ V D ++ FL+ P+T H +D SPL Sbjct: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285 Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325 +L L +FELVV+L VE+T+ Q R+SY+P E+ WG F PV+ + +Y Sbjct: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344 Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354 D+ F + + P T C+ E + E+ Sbjct: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372 >gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapiens] Length = 436 Score = 256 bits (653), Expect = 3e-68 Identities = 133/329 (40%), Positives = 199/329 (60%), Gaps = 5/329 (1%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R + K GH NVR + G YL DL+TT +D++WR+ LF+ +F+ +W LFG+ + Sbjct: 49 RGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAF 108 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IA +HGDL P + PC V S AFLF+LE+QT+IGYGVRS+TEECP A+ Sbjct: 109 WLIASLHGDLAAPPPPA---PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAA 165 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 +V Q + +++ F+ G +AK+A+PKKR ET+ FS AV+ ++ +LCL+ +V N+R+S Sbjct: 166 VVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRS 225 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETSPLR 265 L++ + +LLQ VT EGE I L+ V D ++ FL+ P+T H +D SPL Sbjct: 226 HLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLY 285 Query: 266 DLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVA 325 +L L +FELVV+L VE+T+ Q R+SY+P E+ WG F PV+ + +Y Sbjct: 286 ELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL-FQRGSQYEV 344 Query: 326 DFSQFEQIRKSPDCTFYCADSEKQQLEEK 354 D+ F + + P T C+ E + E+ Sbjct: 345 DYRHFHRTYEVPG-TPVCSAKELDERAEQ 372 >gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] Length = 501 Score = 253 bits (646), Expect = 2e-67 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%) Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 K R R + K+G NV+ + YL DL+TT++D+KWR+ L +F T+ + W Sbjct: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 Query: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142 +++ IA+ GDL + N+TPC+ V + AFLF +E++ TIGYG R IT++CP Sbjct: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158 Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202 I L + Q ++ ++++ F+ G K+++PKKRAET+ FS AVI+ ++GKL L+ +V N+ Sbjct: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218 Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262 R S ++ Q+ KLL++ T EGE + L+Q + + ++ FL+ P+T HV+D S Sbjct: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278 Query: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322 P DL+ ++++ ++FE+VV+L VE+T CQ+RTSY +E+ WG F PV+SL + G Sbjct: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337 Query: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351 + D+SQF + P + + E+ L Sbjct: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366 >gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] Length = 423 Score = 252 bits (644), Expect = 3e-67 Identities = 125/320 (39%), Positives = 200/320 (62%), Gaps = 3/320 (0%) Query: 13 LVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAA 72 L +H + K R + K G NV V Y YL D++TT++D+KWR+ L +F Sbjct: 40 LPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVM 98 Query: 73 TFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGV 132 + +TW FG+I++ IA+I GD++ E S TPC+ ++ AFLFS+E++TTIGYG Sbjct: 99 VYTVTWLFFGMIWWLIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGY 157 Query: 133 RSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGK 192 R IT++CP I LL+ Q V+ +++ F+ G KI++PKKRAET+ FS AVI+ ++GK Sbjct: 158 RVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGK 217 Query: 193 LCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPM 252 LCL+ +V ++R S +++ + KL+++ T EGE I LNQ + + + FL+ P+ Sbjct: 218 LCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPL 277 Query: 253 TFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFV 312 H +++ SP +++ L ++E E+VV+L VE+T CQ+R+SYI EI WG+ F Sbjct: 278 IISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFT 337 Query: 313 PVVSLSKNGKYVADFSQFEQ 332 PV++L ++G Y D++ F + Sbjct: 338 PVLTL-EDGFYEVDYNSFHE 356 >gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapiens] Length = 390 Score = 242 bits (618), Expect = 3e-64 Identities = 126/333 (37%), Positives = 201/333 (60%), Gaps = 7/333 (2%) Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 + R R +SK G+ NV + +LQD++TT++D+KW + L +F +F+ +W LF Sbjct: 29 RQRRARFVSKKGNCNVAHKNIRE-QGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87 Query: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142 + ++ IAF HGDL P E + PC+ + S + AFLFS+E Q TIG+G R +TEECP A Sbjct: 88 MAWWLIAFAHGDLAPSEGTAE--PCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLA 145 Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202 I +L+ Q ++ +I + G K A+ +RAET+ FS AVI ++G+LC +++V ++ Sbjct: 146 ILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDL 205 Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262 RKS++I + ++++ + EGE + L+Q + S FL+ P+ YHV+D S Sbjct: 206 RKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANS 265 Query: 263 PLRDLTPQNL-KEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNG 321 PL DL P +L ++ E++V+L VE+T Q+RTSY+ +EI WG FVP+V+ ++G Sbjct: 266 PLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVA-EEDG 324 Query: 322 KYVADFSQFEQIRK--SPDCTFYCADSEKQQLE 352 +Y D+S+F K +P CT D + LE Sbjct: 325 RYSVDYSKFGNTVKVPTPLCTARQLDEDHSLLE 357 >gi|25121970 potassium inwardly-rectifying channel subfamily J9 [Homo sapiens] Length = 393 Score = 238 bits (608), Expect = 5e-63 Identities = 117/315 (37%), Positives = 193/315 (61%), Gaps = 3/315 (0%) Query: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 + R R + K G NV+ V Y YL DL+TT++D++WR L F + +TW FG Sbjct: 18 RRGRQRYVEKDGRCNVQQGNVRETYR-YLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFG 76 Query: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142 I++ IA+ GDLE E + TPC+ ++ AFLFS+E++TTIGYG R IT++CP Sbjct: 77 AIWWLIAYGRGDLEHLEDTA-WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEG 135 Query: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202 I LL+ Q ++ +++ F+ G KI++P KRA T+ FS AV++ ++G+LCL+ +V ++ Sbjct: 136 IVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDL 195 Query: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262 R S +++ + KL+++ T EGE I L+Q + D+ + FL+ P+ H +D S Sbjct: 196 RSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAAS 255 Query: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322 P + + + L+ +FE+VV+L VE+T CQ+R+SY+ +E+ WG F V++L ++G Sbjct: 256 PFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGF 314 Query: 323 YVADFSQFEQIRKSP 337 Y D++ F + + P Sbjct: 315 YEVDYASFHETFEVP 329 >gi|156119627 potassium inwardly-rectifying channel J13 [Homo sapiens] Length = 360 Score = 237 bits (604), Expect = 1e-62 Identities = 135/326 (41%), Positives = 194/326 (59%), Gaps = 20/326 (6%) Query: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87 R+++K GHS +++D L YL+D W ++DM+WR+ + +F+A+FV+ W +F V++Y Sbjct: 19 RMVTKDGHSTLQMDGAQR-GLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77 Query: 88 IAFIHGDLEPGE--PISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 +A ++GDLE P NHT C+ + S T AF FSLE+Q TIGYG + +CP AI L Sbjct: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 L Q+++ ++E FITG F+AKIARPK RA +I+F+ AV+ +GK L+ QVAN R S Sbjct: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD--SSSESPFLILPMTFYHVLDETSP 263 L ++S L Q E E L Q +V FH+D SS E PF I P+T+YH + +SP Sbjct: 198 PLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252 Query: 264 LRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKY 323 L L Q+ FELVV L+A E T +CQ RTSY+P EI F +++ G+Y Sbjct: 253 LATLL-QHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311 Query: 324 VADFSQFEQ---------IRKSPDCT 340 F++ + KSP+ T Sbjct: 312 QIKMENFDKTVPEFPTPLVSKSPNRT 337 >gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] Length = 424 Score = 227 bits (578), Expect = 2e-59 Identities = 123/329 (37%), Positives = 196/329 (59%), Gaps = 21/329 (6%) Query: 26 RPRVMSKSG-----HSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFL 80 + R ++KSG H N+R +LQD++TT++D+KWR+ L +F +F+ +W L Sbjct: 33 KARFIAKSGACNLAHKNIREQG------RFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLL 86 Query: 81 FGVIYYAIAFIHGDL-----EPGEPISN--HTPCIMKVDSLTGAFLFSLESQTTIGYGVR 133 F ++++ +AF HGD+ + G S T C+ V S T AFLFS+E Q TIG+G R Sbjct: 87 FAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGR 146 Query: 134 SITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKL 193 +TEECP AI +L+ Q ++ +I + G K A+ +RAET+ FS AVI +NGKL Sbjct: 147 MMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKL 206 Query: 194 CLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMT 253 C + +V ++RKS++I + ++++ T EGE + ++Q + S + FL+ P+ Sbjct: 207 CFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLI 266 Query: 254 FYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVP 313 HV+D+ SPL D++ +L ++ E++V+L VE+T Q+RTSYI EEI WG FV Sbjct: 267 ICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVS 326 Query: 314 VVSLSKNGKYVADFSQFEQIRK--SPDCT 340 +V+ + G Y D+S+F K +P C+ Sbjct: 327 IVT-EEEGVYSVDYSKFGNTVKVAAPRCS 354 >gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 216 bits (551), Expect = 2e-56 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++ Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ + Sbjct: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 ++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R + Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264 +++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263 Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324 L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322 Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351 + QFE + +P C+ D + QQL Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351 >gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 216 bits (551), Expect = 2e-56 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++ Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ + Sbjct: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 ++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R + Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264 +++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263 Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324 L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322 Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351 + QFE + +P C+ D + QQL Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351 >gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 216 bits (551), Expect = 2e-56 Identities = 122/329 (37%), Positives = 196/329 (59%), Gaps = 13/329 (3%) Query: 26 RPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIY 85 R R++ K G NV + G + Y+ D++TT++D KWR+ +F+ +++++W +FG ++ Sbjct: 33 RRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92 Query: 86 YAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145 + IAF HGDL I TPC+ V S TGAFLFSLE+QTTIGYG R +TEEC A+ + Sbjct: 93 WLIAFHHGDLLNDPDI---TPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLM 149 Query: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205 ++ Q +++ +I FI G LAK+A +KRA+TI+FS+ A+I ++GKLCL+ ++ + R + Sbjct: 150 VILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPN 209 Query: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKF-HVDSSSESPFLILPMTFYHVLDETSPL 264 +++ + +LL+ EG + T+ F + ++ L+ P+T H +D SPL Sbjct: 210 HVVEGTVRAQLLRYTEDSEG------RMTMAFKDLKLVNDQIILVTPVTIVHEIDHESPL 263 Query: 265 RDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYV 324 L + + + FE++V T +ST QSR+SY+P EI WG F V+ + K Y Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEV-KRKYYK 322 Query: 325 ADFSQFEQIRK--SPDCTFYCADSEKQQL 351 + QFE + +P C+ D + QQL Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQL 351 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 31.6 bits (70), Expect = 1.2 Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 6/95 (6%) Query: 271 NLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKYVADFSQF 330 NL EKE E+ +T++ + +EIY E + +S+ + V + QF Sbjct: 1499 NLSEKETEI-----STIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF 1553 Query: 331 EQIRKSPDCTFYCADSEKQQLEEKYRQEDQREREL 365 ++ RK+ D +S+ +L + QE Q E ++ Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRL-QESQEEIQI 1587 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.136 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,676,353 Number of Sequences: 37866 Number of extensions: 508375 Number of successful extensions: 1902 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 36 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 1838 Number of HSP's gapped (non-prelim): 56 length of query: 375 length of database: 18,247,518 effective HSP length: 104 effective length of query: 271 effective length of database: 14,309,454 effective search space: 3877862034 effective search space used: 3877862034 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.