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Search of human proteins with 21265113
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens]
(197 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens] 422 e-119
gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens] 195 2e-50
gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens] 169 1e-42
gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens] 129 2e-30
gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens] 109 2e-24
gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens] 59 2e-09
gi|13994372 keratin associated protein 17-1 [Homo sapiens] 33 0.16
gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo s... 32 0.27
gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo s... 32 0.27
gi|6912666 sialin [Homo sapiens] 31 0.60
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 31 0.60
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 31 0.78
gi|54400749 keratin associated protein 5-1 [Homo sapiens] 29 3.0
gi|109255251 loricrin [Homo sapiens] 28 3.9
gi|67003568 skin-specific protein 32 [Homo sapiens] 28 5.0
gi|8394398 taste receptor T2R3 [Homo sapiens] 28 5.0
gi|21314671 transient receptor potential cation channel, subfami... 27 8.6
gi|148613866 tudor domain containing 10 isoform a [Homo sapiens] 27 8.6
gi|157738623 olfactory receptor, family 51, subfamily B, member ... 27 8.6
gi|148613864 tudor domain containing 10 isoform b [Homo sapiens] 27 8.6
>gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens]
Length = 197
Score = 422 bits (1085), Expect = e-119
Identities = 197/197 (100%), Positives = 197/197 (100%)
Query: 1 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60
MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV
Sbjct: 1 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60
Query: 61 LCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLM 120
LCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLM
Sbjct: 61 LCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLM 120
Query: 121 NGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNA 180
NGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNA
Sbjct: 121 NGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNA 180
Query: 181 TIGVFCGDCRKKQDTPH 197
TIGVFCGDCRKKQDTPH
Sbjct: 181 TIGVFCGDCRKKQDTPH 197
>gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens]
Length = 202
Score = 195 bits (496), Expect = 2e-50
Identities = 93/197 (47%), Positives = 121/197 (61%), Gaps = 4/197 (2%)
Query: 1 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60
MC GKCARC+G SL+ L L+CI AN LL PNGET + + NHLS VW G +GGGL++
Sbjct: 1 MCYGKCARCIGHSLVGLALLCIAANILLYFPNGETKYASENHLSRFVWFFSGIVGGGLLM 60
Query: 61 LCPG---IAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPR 117
L P I + GCCG CG RC ML SV ++ G+ G+ YC+ V+ GL GP
Sbjct: 61 LLPAFVFIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIGIAGSGYCVIVAALGLAEGPL 120
Query: 118 CLMN-GEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQ 176
CL + G+W Y F T G YLL+ + W C P +V WNV+LFS+L+A +E +LC IQ
Sbjct: 121 CLDSLGQWNYTFASTEGQYLLDTSTWSECTEPKHIVEWNVSLFSILLALGGIEFILCLIQ 180
Query: 177 LVNATIGVFCGDCRKKQ 193
++N +G CG C Q
Sbjct: 181 VINGVLGGICGFCCSHQ 197
>gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens]
Length = 202
Score = 169 bits (428), Expect = 1e-42
Identities = 84/196 (42%), Positives = 114/196 (58%), Gaps = 11/196 (5%)
Query: 1 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60
MCTG CARC+G +LI L +AN LL P G+ N +HLS ++W GG +G G+++
Sbjct: 1 MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDN-DHLSQEIWFFGGILGSGVLM 59
Query: 61 LCPGIAAVRAGGKGCCGAGCCGN-----RCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNG 115
+ P + + CCG CCGN R M S + G LGA Y +S + G
Sbjct: 60 IFPALVFLGLKNNDCCG--CCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKG 117
Query: 116 PRCLM-NGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCG 174
P+CLM N WGY F D G YL + LW++C P VVPWN+TLFS+L+ +++VLC
Sbjct: 118 PKCLMANSTWGYPFHD--GDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCA 175
Query: 175 IQLVNATIGVFCGDCR 190
IQ+VN +G CGDC+
Sbjct: 176 IQVVNGLLGTLCGDCQ 191
>gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens]
Length = 201
Score = 129 bits (323), Expect = 2e-30
Identities = 67/190 (35%), Positives = 100/190 (52%), Gaps = 3/190 (1%)
Query: 1 MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60
M + KC C+ LI L L I+ N LL PNG+TS+ ++N L+ VW G G+M+
Sbjct: 1 MGSRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMM 60
Query: 61 LCPGIAAVRAGGKG---CCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPR 117
L + CC + C + L S+ S+ G+ + YCL +S GL GP
Sbjct: 61 LIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPY 120
Query: 118 CLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQL 177
C W Y FE TAG +L + ++W +C P VV WN+ LFS+L+ S L++++C I++
Sbjct: 121 CRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRV 180
Query: 178 VNATIGVFCG 187
V + CG
Sbjct: 181 VMQLSKILCG 190
>gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]
Length = 209
Score = 109 bits (272), Expect = 2e-24
Identities = 69/199 (34%), Positives = 105/199 (52%), Gaps = 16/199 (8%)
Query: 6 CARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMVLCPGI 65
C+R +GLSL T L AN LL+PN + ++ L L G GGGLMVL I
Sbjct: 14 CSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVLTAAI 73
Query: 66 AAVRAGGK-GCCG-AGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLMN-- 121
G + GC +G C + +L ++ S +LGA+ C SG L++GP C+ +
Sbjct: 74 LISLMGWRYGCFSKSGLCRS---VLTALLSGGLALLGALICFVTSGVALKDGPFCMFDVS 130
Query: 122 -------GEWGYHFEDTAGA-YLLNRTLWDR-CEAPPRVVPWNVTLFSLLVAASCLEIVL 172
++GY F+D YL +R+LW+ C P V W+V+LFS L+ S L+++L
Sbjct: 131 SFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCISLLQLLL 190
Query: 173 CGIQLVNATIGVFCGDCRK 191
+ ++N+ +G+FC C K
Sbjct: 191 VVVHVINSLLGLFCSLCEK 209
>gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens]
Length = 229
Score = 59.3 bits (142), Expect = 2e-09
Identities = 39/116 (33%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 2 CTGKCARCVGLSLITLCLVCIVANAL-LLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMV 60
C C G SL+ L L+ +V NA+ L+V E + N +S W G IG GLM
Sbjct: 3 CCEGWTSCNGFSLLVLLLLGVVLNAIPLIVSLVEEDQFSQNPISCFEWWFPGIIGAGLMA 62
Query: 61 LCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGP 116
+ ++ A + CC NR M S S V+GA+YC+ +S L GP
Sbjct: 63 IPATTMSLTARKRACCN-----NRTGMFLSSLFSVITVIGALYCMLISIQALLKGP 113
>gi|13994372 keratin associated protein 17-1 [Homo sapiens]
Length = 105
Score = 33.1 bits (74), Expect = 0.16
Identities = 11/24 (45%), Positives = 13/24 (54%)
Query: 62 CPGIAAVRAGGKGCCGAGCCGNRC 85
C G G GCCG+ CCG+ C
Sbjct: 62 CGGCGGCGGCGGGCCGSSCCGSSC 85
Score = 32.0 bits (71), Expect = 0.35
Identities = 21/62 (33%), Positives = 25/62 (40%), Gaps = 6/62 (9%)
Query: 62 CPGIAAVRAGGKGC----CGAGCCGNRCRMLRSVFSSAFGVLGAIYC-LSVSGAGLRNGP 116
C G GG GC CG+ CCG+ C G G+ C S G+G GP
Sbjct: 35 CCGCGGSGCGGSGCGGSCCGSSCCGSGCGGCGGCGGCGGGCCGSSCCGSSCCGSGC-CGP 93
Query: 117 RC 118
C
Sbjct: 94 VC 95
Score = 30.0 bits (66), Expect = 1.3
Identities = 15/34 (44%), Positives = 17/34 (50%), Gaps = 7/34 (20%)
Query: 52 GFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRC 85
G GGG C G + G CCG+GCCG C
Sbjct: 69 GGCGGG----CCGSSCC---GSSCCGSGCCGPVC 95
>gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo
sapiens]
Length = 1074
Score = 32.3 bits (72), Expect = 0.27
Identities = 29/110 (26%), Positives = 41/110 (37%), Gaps = 24/110 (21%)
Query: 61 LCPGIAAVRAGGKGCCGAGCCG---NRCRMLRSVFSSAFGVLGAIYCLSVSGAGLR---- 113
L PG + G+ G G CG + CR++ + G LG L + LR
Sbjct: 457 LSPGCDGILGSGRRPDGCGVCGGDDSTCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIA 516
Query: 114 -------------NGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPR 150
G R ++NG W D G+Y T++ R PPR
Sbjct: 517 QLRPSSNYLALRGPGGRSIINGNWAV---DPPGSYRAGGTVF-RYNRPPR 562
>gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo
sapiens]
Length = 877
Score = 32.3 bits (72), Expect = 0.27
Identities = 29/110 (26%), Positives = 41/110 (37%), Gaps = 24/110 (21%)
Query: 61 LCPGIAAVRAGGKGCCGAGCCG---NRCRMLRSVFSSAFGVLGAIYCLSVSGAGLR---- 113
L PG + G+ G G CG + CR++ + G LG L + LR
Sbjct: 457 LSPGCDGILGSGRRPDGCGVCGGDDSTCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIA 516
Query: 114 -------------NGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPR 150
G R ++NG W D G+Y T++ R PPR
Sbjct: 517 QLRPSSNYLALRGPGGRSIINGNWAV---DPPGSYRAGGTVF-RYNRPPR 562
>gi|6912666 sialin [Homo sapiens]
Length = 495
Score = 31.2 bits (69), Expect = 0.60
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 1/67 (1%)
Query: 46 QVWLMGGFIGGGLMVLCPG-IAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYC 104
Q W++G F G ++ PG A + GGK G G G L + ++ GV I
Sbjct: 108 QGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVL 167
Query: 105 LSVSGAG 111
++ G G
Sbjct: 168 RALEGLG 174
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 31.2 bits (69), Expect = 0.60
Identities = 18/63 (28%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 12 LSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIG--GGLMVLCPGIAAVR 69
LS T+ + I+ + + + P G + + L+L VW++GG + G L G+A +
Sbjct: 43 LSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPK 102
Query: 70 AGG 72
+GG
Sbjct: 103 SGG 105
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 30.8 bits (68), Expect = 0.78
Identities = 14/39 (35%), Positives = 18/39 (46%)
Query: 112 LRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPR 150
L P +NGEW H + + Y NR +R PPR
Sbjct: 259 LPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPR 297
>gi|54400749 keratin associated protein 5-1 [Homo sapiens]
Length = 278
Score = 28.9 bits (63), Expect = 3.0
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 51 GGFIGG-GLMVLCPGIAAVRAGGKGCCGAGC--CGNRC 85
GG GG G C G G KG CG+GC CG+ C
Sbjct: 171 GGSKGGCGSCGGCKGGCGSCGGSKGGCGSGCGGCGSGC 208
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 28.5 bits (62), Expect = 3.9
Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 14/84 (16%)
Query: 51 GGFIGG-----GLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVL--GAIY 103
GG IGG G V G GG GC +G G+ C FSS G G
Sbjct: 74 GGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGC------FSSGGGGSSGGGSG 127
Query: 104 CLSVSGAGLR-NGPRCLMNGEWGY 126
C S G G G C +G G+
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGF 151
>gi|67003568 skin-specific protein 32 [Homo sapiens]
Length = 250
Score = 28.1 bits (61), Expect = 5.0
Identities = 9/16 (56%), Positives = 11/16 (68%)
Query: 70 AGGKGCCGAGCCGNRC 85
+G GCCG+G CG C
Sbjct: 204 SGSSGCCGSGGCGCSC 219
>gi|8394398 taste receptor T2R3 [Homo sapiens]
Length = 316
Score = 28.1 bits (61), Expect = 5.0
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 15/51 (29%)
Query: 12 LSLITLCLVCIVANALLLV---PNG----------ETSWTNTNHLSLQVWL 49
L+L+ + L+CI+ L+ PN + SWT TNHLS +WL
Sbjct: 51 LALLRIILLCIILTDSFLIEFSPNTHDSGIIMQIIDVSWTFTNHLS--IWL 99
>gi|21314671 transient receptor potential cation channel, subfamily
M, member 4 [Homo sapiens]
Length = 1214
Score = 27.3 bits (59), Expect = 8.6
Identities = 9/17 (52%), Positives = 11/17 (64%)
Query: 69 RAGGKGCCGAGCCGNRC 85
++G GCCG C G RC
Sbjct: 752 QSGRPGCCGGRCGGRRC 768
>gi|148613866 tudor domain containing 10 isoform a [Homo sapiens]
Length = 366
Score = 27.3 bits (59), Expect = 8.6
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 11/53 (20%)
Query: 107 VSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLF 159
+ G+ + G RCL YH D A W+RC RV W V +F
Sbjct: 240 LEGSTVMRGTRCLAE----YHLGDYGHA-------WNRCWVLDRVDTWAVVMF 281
>gi|157738623 olfactory receptor, family 51, subfamily B, member 2
[Homo sapiens]
Length = 312
Score = 27.3 bits (59), Expect = 8.6
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 156 VTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKK 192
V L SL + CL I+ I ++N IG+ G+ R K
Sbjct: 198 VILISLTIFLDCLIILFSYILILNTVIGIASGEERAK 234
>gi|148613864 tudor domain containing 10 isoform b [Homo sapiens]
Length = 351
Score = 27.3 bits (59), Expect = 8.6
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 11/53 (20%)
Query: 107 VSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLF 159
+ G+ + G RCL YH D A W+RC RV W V +F
Sbjct: 240 LEGSTVMRGTRCLAE----YHLGDYGHA-------WNRCWVLDRVDTWAVVMF 281
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.143 0.496
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,651,044
Number of Sequences: 37866
Number of extensions: 391621
Number of successful extensions: 1430
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1375
Number of HSP's gapped (non-prelim): 40
length of query: 197
length of database: 18,247,518
effective HSP length: 97
effective length of query: 100
effective length of database: 14,574,516
effective search space: 1457451600
effective search space used: 1457451600
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.