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Search of human proteins with 21070967
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]
(442 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens] 887 0.0
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 704 0.0
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 688 0.0
gi|41350305 neurexin 3 isoform 2 precursor [Homo sapiens] 545 e-155
gi|157427673 neurexin 3 isoform 3 precursor [Homo sapiens] 523 e-148
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens] 482 e-136
gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens] 419 e-117
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] 382 e-106
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] 366 e-101
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 63 5e-10
gi|4505463 contactin associated protein 1 precursor [Homo sapiens] 55 1e-07
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap... 53 5e-07
gi|18640734 contactin associated protein-like 5 [Homo sapiens] 46 6e-05
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 46 8e-05
gi|188528675 slit homolog 1 [Homo sapiens] 42 0.001
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 41 0.002
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 41 0.002
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 41 0.002
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 40 0.003
gi|8051605 glycophorin C isoform 2 [Homo sapiens] 40 0.003
gi|4504229 glycophorin C isoform 1 [Homo sapiens] 40 0.003
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 40 0.004
gi|33469931 EGF-like, fibronectin type III and laminin G domains... 40 0.004
gi|33469929 EGF-like, fibronectin type III and laminin G domains... 40 0.004
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 40 0.006
gi|5032007 purine-rich element binding protein A [Homo sapiens] 39 0.007
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol... 39 0.007
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo... 39 0.007
gi|154091020 leucine-rich repeats and calponin homology (CH) dom... 39 0.007
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 39 0.007
>gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]
Length = 442
Score = 887 bits (2291), Expect = 0.0
Identities = 442/442 (100%), Positives = 442/442 (100%)
Query: 1 MYQRMLRCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIH 60
MYQRMLRCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIH
Sbjct: 1 MYQRMLRCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIH 60
Query: 61 HFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIG 120
HFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIG
Sbjct: 61 HFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIG 120
Query: 121 FSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVV 180
FSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVV
Sbjct: 121 FSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVV 180
Query: 181 RFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGL 240
RFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGL
Sbjct: 181 RFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGL 240
Query: 241 KVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARR 300
KVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARR
Sbjct: 241 KVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARR 300
Query: 301 GKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIR 360
GKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIR
Sbjct: 301 GKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIR 360
Query: 361 ESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKE 420
ESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKE
Sbjct: 361 ESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKE 420
Query: 421 KQPSSAKSSNKNKKNKDKEYYV 442
KQPSSAKSSNKNKKNKDKEYYV
Sbjct: 421 KQPSSAKSSNKNKKNKDKEYYV 442
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 704 bits (1817), Expect = 0.0
Identities = 355/355 (100%), Positives = 355/355 (100%)
Query: 88 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 147
GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI
Sbjct: 1123 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 1182
Query: 148 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQ 207
HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQ
Sbjct: 1183 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQ 1242
Query: 208 LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS 267
LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS
Sbjct: 1243 LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS 1302
Query: 268 SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDD 327
SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDD
Sbjct: 1303 SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDD 1362
Query: 328 EDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAM 387
EDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAM
Sbjct: 1363 EDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAM 1422
Query: 388 YKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
YKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV
Sbjct: 1423 YKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 1477
Score = 42.7 bits (99), Expect = 7e-04
Identities = 48/188 (25%), Positives = 78/188 (41%), Gaps = 28/188 (14%)
Query: 95 KGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGV 154
KG Y N S+ +D + + F T+Q+ +++ S+ DY+ L + G + +
Sbjct: 287 KGSEYFCYDLSQNPIQSS-SDEITLSFKTLQRNGLMLHTGKSA---DYVNLALKNGAVSL 342
Query: 155 KFNVGTD--DIAIEESNAIINDGKYHVVRFTR-----SG-GNA--TLQVDSWPVIERYPA 204
N+G+ + +E N ND +H V+ TR SG G+A T+ VD Y
Sbjct: 343 VINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGY-T 401
Query: 205 GRQLTIFNSQATIIIGGKEQ-----GQP----FQGQLSGLYYNG----LKVLNMAAENDA 251
T+ S +GG G P F G L + Y L++ +A + D
Sbjct: 402 QEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDP 461
Query: 252 NIAIVGNV 259
+ I G V
Sbjct: 462 KMKIHGVV 469
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 29/157 (18%)
Query: 130 LVRVDSSSGLGDYLELHIHQG-KIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGN 188
LV G D+LEL + +G ++ + F++ + A ++ +NDG +H VR R N
Sbjct: 66 LVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRN 125
Query: 189 ATLQVD----SWPVIERYPAGRQLTIFN-------------SQATIIIGGKEQGQPFQGQ 231
TL +D W +E R +T+F+ + + + + +PF+G
Sbjct: 126 TTLFIDQVEAKW--VEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGW 183
Query: 232 LSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSS 268
+ + N +VL + + G V+L E P+S
Sbjct: 184 IRDVRVNSSQVLPVDS---------GEVKLDDEPPNS 211
Score = 38.1 bits (87), Expect = 0.016
Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 112 TRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
T A+ +++ F + + +L+ S D L L + G+ VK V D I I +++
Sbjct: 737 TEAEDVSLRFRSQRAYGILMATTSRDS-ADTLRLELDAGR--VKLTVNLDCIRINCNSSK 793
Query: 172 ----------INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAG--RQLTIFNSQATIII 219
+ND ++H VR R G + L VD + AG +L N + II
Sbjct: 794 GPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIIT 853
Query: 220 GGK---EQGQPFQGQLSGLYYNGLKVLNMAAEND 250
+ F G L L +NG+ +++ D
Sbjct: 854 ERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGD 887
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 141 DYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 200
D+ + + G + + ++G+ I I+ +NDG+++ V F R G + T+ V++ +
Sbjct: 539 DFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNT--LRT 596
Query: 201 RYPAGRQLTIFNSQATIIIGG 221
Y A + I + + +GG
Sbjct: 597 PYTAPGESEILDLDDELYLGG 617
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 688 bits (1776), Expect = 0.0
Identities = 355/385 (92%), Positives = 355/385 (92%), Gaps = 30/385 (7%)
Query: 88 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 147
GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI
Sbjct: 1163 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 1222
Query: 148 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAG-- 205
HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAG
Sbjct: 1223 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNN 1282
Query: 206 ----------------------------RQLTIFNSQATIIIGGKEQGQPFQGQLSGLYY 237
RQLTIFNSQATIIIGGKEQGQPFQGQLSGLYY
Sbjct: 1283 DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYY 1342
Query: 238 NGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATST 297
NGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATST
Sbjct: 1343 NGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATST 1402
Query: 298 ARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAE 357
ARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAE
Sbjct: 1403 ARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAE 1462
Query: 358 VIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAV 417
VIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAV
Sbjct: 1463 VIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAV 1522
Query: 418 VKEKQPSSAKSSNKNKKNKDKEYYV 442
VKEKQPSSAKSSNKNKKNKDKEYYV
Sbjct: 1523 VKEKQPSSAKSSNKNKKNKDKEYYV 1547
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/157 (24%), Positives = 69/157 (43%), Gaps = 29/157 (18%)
Query: 130 LVRVDSSSGLGDYLELHIHQG-KIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGN 188
LV G D+LEL + +G ++ + F++ + A ++ +NDG +H VR R N
Sbjct: 66 LVLYFDDEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDGAWHSVRIRRQFRN 125
Query: 189 ATLQVD----SWPVIERYPAGRQLTIFN-------------SQATIIIGGKEQGQPFQGQ 231
TL +D W +E R +T+F+ + + + + +PF+G
Sbjct: 126 TTLFIDQVEAKW--VEVKSKRRDMTVFSGLFVGGLPPELRAAALKLTLASVREREPFKGW 183
Query: 232 LSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSS 268
+ + N +VL + + G V+L E P+S
Sbjct: 184 IRDVRVNSSQVLPVDS---------GEVKLDDEPPNS 211
Score = 40.4 bits (93), Expect = 0.003
Identities = 24/93 (25%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 95 KGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGV 154
KG Y N S+ +D + + F T+Q+ +++ S+ DY+ L + G + +
Sbjct: 320 KGSEYFCYDLSQNPIQSS-SDEITLSFKTLQRNGLMLHTGKSA---DYVNLALKNGAVSL 375
Query: 155 KFNVGTD--DIAIEESNAIINDGKYHVVRFTRS 185
N+G+ + +E N ND +H V+ TR+
Sbjct: 376 VINLGSGAFEALVEPVNGKFNDNAWHDVKVTRN 408
Score = 38.1 bits (87), Expect = 0.016
Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 18/154 (11%)
Query: 112 TRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
T A+ +++ F + + +L+ S D L L + G+ VK V D I I +++
Sbjct: 777 TEAEDVSLRFRSQRAYGILMATTSRDS-ADTLRLELDAGR--VKLTVNLDCIRINCNSSK 833
Query: 172 ----------INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAG--RQLTIFNSQATIII 219
+ND ++H VR R G + L VD + AG +L N + II
Sbjct: 834 GPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGDHTRLEFHNIETGIIT 893
Query: 220 GGK---EQGQPFQGQLSGLYYNGLKVLNMAAEND 250
+ F G L L +NG+ +++ D
Sbjct: 894 ERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGD 927
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 141 DYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 200
D+ + + G + + ++G+ I I+ +NDG+++ V F R G + T+ V++ +
Sbjct: 579 DFFAIEMLDGHLYLLLDMGSGTIKIKALLKKVNDGEWYHVDFQRDGRSGTISVNT--LRT 636
Query: 201 RYPAGRQLTIFNSQATIIIGG 221
Y A + I + + +GG
Sbjct: 637 PYTAPGESEILDLDDELYLGG 657
>gi|41350305 neurexin 3 isoform 2 precursor [Homo sapiens]
Length = 432
Score = 545 bits (1403), Expect = e-155
Identities = 281/394 (71%), Positives = 323/394 (81%), Gaps = 9/394 (2%)
Query: 51 ASSLGAH--HIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPND 108
+SS G+H H HHFHGS KHHSVPI+IYRSP SLRGGHAG TYIF K GG I Y WP ND
Sbjct: 46 SSSPGSHSQHEHHFHGS-KHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPAND 104
Query: 109 RPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES 168
RPSTR+DRLA+GFST K+ +LVR+DS+ GLGD+L+LHI QGKIGV FN+GT DI+I+E
Sbjct: 105 RPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEE 164
Query: 169 NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQPF 228
+NDGKYHVVRFTR+GGNATLQVD+WPV E YP GRQLTIFN+QA I IGGK++G+ F
Sbjct: 165 RTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGGKDKGRLF 224
Query: 229 QGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMSTSIME 288
QGQLSGLYY+GLKVLNMAAEN+ NI I G+VRLVGEVPS + T T T+M EMST++ME
Sbjct: 225 QGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT-TSMPPEMSTTVME 283
Query: 289 TTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGG 348
TTTT+AT+T R+ + Q T D LV+SAEC SDDED CEPS+G ANPT G
Sbjct: 284 TTTTMATTTTRKNRSTAS---IQPTSDDLVSSAECSSDDEDFVECEPSTGRSANPTEPGI 340
Query: 349 REPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYIS 408
R PG++EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY VDE+RNYIS
Sbjct: 341 RR-VPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYIS 399
Query: 409 NSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
NSAQSNG ++KEKQ SS KS +K +KNKD+EYYV
Sbjct: 400 NSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 432
>gi|157427673 neurexin 3 isoform 3 precursor [Homo sapiens]
Length = 459
Score = 523 bits (1346), Expect = e-148
Identities = 280/424 (66%), Positives = 322/424 (75%), Gaps = 42/424 (9%)
Query: 51 ASSLGAH--HIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPND 108
+SS G+H H HHFHGS KHHSVPI+IYRSP SLRGGHAG TYIF K GG I Y WP ND
Sbjct: 46 SSSPGSHSQHEHHFHGS-KHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYTWPAND 104
Query: 109 RPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES 168
RPSTR+DRLA+GFST K+ +LVR+DS+ GLGD+L+LHI QGKIGV FN+GT DI+I+E
Sbjct: 105 RPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEE 164
Query: 169 NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAG----------------------- 205
+NDGKYHVVRFTR+GGNATLQVD+WPV E YP G
Sbjct: 165 RTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKYNRPVE 224
Query: 206 -------RQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGN 258
RQLTIFN+QA I IGGK++G+ FQGQLSGLYY+GLKVLNMAAEN+ NI I G+
Sbjct: 225 EWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGS 284
Query: 259 VRLVGEVPSSMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILV 318
VRLVGEVPS + T T T+M EMST++METTTT+AT+T R+ + Q T D LV
Sbjct: 285 VRLVGEVPSILGTTQT-TSMPPEMSTTVMETTTTMATTTTRKNRSTAS---IQPTSDDLV 340
Query: 319 ASAECPSDDEDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAAL 378
+SAEC SDDED CEPS+ ANPT G R PG++EVIRESSSTTGMVVGIVAAAAL
Sbjct: 341 SSAECSSDDEDFVECEPST---ANPTEPGIRR-VPGASEVIRESSSTTGMVVGIVAAAAL 396
Query: 379 CILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDK 438
CILILLYAMYKYRNRDEGSY VDE+RNYISNSAQSNG ++KEKQ SS KS +K +KNKD+
Sbjct: 397 CILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDR 455
Query: 439 EYYV 442
EYYV
Sbjct: 456 EYYV 459
>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
Length = 1061
Score = 482 bits (1241), Expect = e-136
Identities = 250/355 (70%), Positives = 289/355 (81%), Gaps = 9/355 (2%)
Query: 88 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 147
G TYIF K GG I Y WP NDRPSTR+DRLA+GFST K+ +LVR+DS+ GLGD+L+LHI
Sbjct: 716 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 775
Query: 148 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQ 207
QGKIGV FN+GT DI+I+E +NDGKYHVVRFTR+GGNATLQVD+WPV E YP GRQ
Sbjct: 776 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGRQ 835
Query: 208 LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS 267
LTIFN+QA I IGGK++G+ FQGQLSGLYY+GLKVLNMAAEN+ NI I G+VRLVGEVPS
Sbjct: 836 LTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPS 895
Query: 268 SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDD 327
+ T T T+M EMST++METTTT+AT+T R+ + Q T D LV+SAEC SDD
Sbjct: 896 ILGTTQT-TSMPPEMSTTVMETTTTMATTTTRKNRSTAS---IQPTSDDLVSSAECSSDD 951
Query: 328 EDIDPCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAM 387
ED CEPS+ ANPT G R PG++EVIRESSSTTGMVVGIVAAAALCILILLYAM
Sbjct: 952 EDFVECEPST---ANPTEPGIRR-VPGASEVIRESSSTTGMVVGIVAAAALCILILLYAM 1007
Query: 388 YKYRNRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
YKYRNRDEGSY VDE+RNYISNSAQSNG ++KEKQ SS KS +K +KNKD+EYYV
Sbjct: 1008 YKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 1061
Score = 35.0 bits (79), Expect = 0.14
Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 112 TRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
T A+ ++ F + + +LV S D L L + G++ + N+ I S
Sbjct: 331 TEAEDVSFRFMSQRAYGLLVATTSRDS-ADTLRLELDGGRVKLMVNLDCIRINCNSSKGP 389
Query: 172 --------INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTI-FNSQATIIIGGK 222
+ND ++H VR R G + L VD V E G + F++ T I+ K
Sbjct: 390 ETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDD-DVAEGTMVGDHTRLEFHNIETGIMTEK 448
Query: 223 EQ----GQPFQGQLSGLYYNGLKVLNMAAEND 250
F G L L +NGL +++ D
Sbjct: 449 RYISVVPSSFIGHLQSLMFNGLLYIDLCKNGD 480
Score = 31.2 bits (69), Expect = 2.0
Identities = 17/81 (20%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 141 DYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 200
D+ + + G + + ++G+ I ++ + NDG+++ V R G + T+ V+S
Sbjct: 133 DFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRT-- 190
Query: 201 RYPAGRQLTIFNSQATIIIGG 221
+ A + I + + + +GG
Sbjct: 191 PFTASGESEILDLEGDMYLGG 211
>gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens]
Length = 666
Score = 419 bits (1078), Expect = e-117
Identities = 229/374 (61%), Positives = 268/374 (71%), Gaps = 51/374 (13%)
Query: 15 PGGGGGGGGGGGAGGRLA-------------LLWIVPLTLSGLLGVAWGA---SSLGA-H 57
P GG G GG LA LL ++PL L LLG A GA SSL H
Sbjct: 2 PPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEGARVSSSLSTTH 61
Query: 58 HIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRL 117
H+HHFH SKH +VPIAI R P RGGHAGTTYIF KGG ITY WPPNDRPSTR DRL
Sbjct: 62 HVHHFH--SKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYTWPPNDRPSTRMDRL 119
Query: 118 AIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKY 177
A+GFST Q+ AVLVRVDS+SGLGDYL+LHI QG +GV FNVGTDDI I+E NAI++DGKY
Sbjct: 120 AVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKY 179
Query: 178 HVVRFTRSGGNATLQVDSWPVIERYPA------------------------------GRQ 207
HVVRFTRSGGNATLQVDSWPV ERYPA GRQ
Sbjct: 180 HVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQ 239
Query: 208 LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS 267
LTIFNSQA I IGG++QG+PFQGQ+SGLYYNGLKVL +AAE+D N+ G++RLVGE PS
Sbjct: 240 LTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPS 299
Query: 268 -SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPT-KEPISQTTDDILVASAECPS 325
++ E+TAT + ++M+T+IMETTTT+AT+T RRG+ PT ++ +Q TDD+LVASAECPS
Sbjct: 300 VLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPS 359
Query: 326 DDEDIDPCEPSSGG 339
DDED++ CEPS+GG
Sbjct: 360 DDEDLEECEPSTGG 373
Score = 164 bits (416), Expect = 1e-40
Identities = 85/102 (83%), Positives = 91/102 (89%), Gaps = 1/102 (0%)
Query: 341 ANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHV 400
ANPT G R P PG+ EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY V
Sbjct: 566 ANPTGPGERGP-PGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
Query: 401 DESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
D+SRNYISNSAQSNGAVVKEK P++ K+ +K KKNKDKEYYV
Sbjct: 625 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
Length = 1642
Score = 382 bits (981), Expect = e-106
Identities = 186/254 (73%), Positives = 221/254 (87%), Gaps = 2/254 (0%)
Query: 88 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 147
GTTYIF KGG ITY WPPNDRPSTR DRLA+GFST Q+ AVLVRVDS+SGLGDYL+LHI
Sbjct: 1096 GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 1155
Query: 148 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQ 207
QG +GV FNVGTDDI I+E NAI++DGKYHVVRFTRSGGNATLQVDSWPV ERYPAGRQ
Sbjct: 1156 DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGRQ 1215
Query: 208 LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS 267
LTIFNSQA I IGG++QG+PFQGQ+SGLYYNGLKVL +AAE+D N+ G++RLVGE PS
Sbjct: 1216 LTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPS 1275
Query: 268 -SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPT-KEPISQTTDDILVASAECPS 325
++ E+TAT + ++M+T+IMETTTT+AT+T RRG+ PT ++ +Q TDD+LVASAECPS
Sbjct: 1276 VLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPS 1335
Query: 326 DDEDIDPCEPSSGG 339
DDED++ CEPS+GG
Sbjct: 1336 DDEDLEECEPSTGG 1349
Score = 164 bits (416), Expect = 1e-40
Identities = 85/102 (83%), Positives = 91/102 (89%), Gaps = 1/102 (0%)
Query: 341 ANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHV 400
ANPT G R P PG+ EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY V
Sbjct: 1542 ANPTGPGERGP-PGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 1600
Query: 401 DESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
D+SRNYISNSAQSNGAVVKEK P++ K+ +K KKNKDKEYYV
Sbjct: 1601 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 1642
Score = 42.7 bits (99), Expect = 7e-04
Identities = 40/168 (23%), Positives = 68/168 (40%), Gaps = 27/168 (16%)
Query: 115 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTD--DIAIEESNAII 172
D + + F T+Q+ +++ S+ DY+ L + G + + N+G+ + +E N
Sbjct: 288 DEITLAFRTLQRNGLMLHTGKSA---DYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKF 344
Query: 173 NDGKYHVVRFTRS--------GGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQ 224
ND +H VR TR+ T+ VD Y T+ S IGG
Sbjct: 345 NDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTTTGY-TQEDYTMLGSDDFFYIGGSPN 403
Query: 225 -----GQP----FQGQLSGLYYNG----LKVLNMAAENDANIAIVGNV 259
G P F G L + Y L++ +A E D + + G++
Sbjct: 404 TADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDL 451
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/144 (25%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 112 TRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
T A+ +++ F + Q+ L+ +S D L L + G++ + N+G + + +
Sbjct: 720 TEAEDVSLRFMS-QRAYGLMMATTSRESADTLRLELDGGQMKLTVNLGKGPETLFAGHKL 778
Query: 172 INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTI-FNSQATIIIGGKE----QGQ 226
ND ++H VR R G + L VD+ +E AG + + F++ T I+ +
Sbjct: 779 -NDNEWHTVRVVRRGKSLQLSVDN-VTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPS 836
Query: 227 PFQGQLSGLYYNGLKVLNMAAEND 250
F G LSGL +NG ++ + D
Sbjct: 837 NFIGHLSGLVFNGQPYMDQCKDGD 860
Score = 36.2 bits (82), Expect = 0.061
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 135 SSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVD 194
SS+ DY + + G + + ++G+ I + S+ +NDG++ V F R G ++ V+
Sbjct: 515 SSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVN 574
Query: 195 SWPVIERYPAGRQLTIFNSQATIIIGGKEQG 225
S + A I + ++ + +GG +G
Sbjct: 575 SRST--PFLATGDSEILDLESELYLGGLPEG 603
Score = 34.7 bits (78), Expect = 0.18
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 117 LAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGK 176
L+ T A+L+ +D G D+LEL + G++ ++F + + A + + + D +
Sbjct: 53 LSFSLRTNATRALLLYLDDG-GDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDR 111
Query: 177 YHVVRFTRSGGNATLQVD 194
+H+V TR L VD
Sbjct: 112 WHMVLLTRDARRTALAVD 129
>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
Length = 1712
Score = 366 bits (940), Expect = e-101
Identities = 186/284 (65%), Positives = 221/284 (77%), Gaps = 32/284 (11%)
Query: 88 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 147
GTTYIF KGG ITY WPPNDRPSTR DRLA+GFST Q+ AVLVRVDS+SGLGDYL+LHI
Sbjct: 1136 GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 1195
Query: 148 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPA--- 204
QG +GV FNVGTDDI I+E NAI++DGKYHVVRFTRSGGNATLQVDSWPV ERYPA
Sbjct: 1196 DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 1255
Query: 205 ---------------------------GRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYY 237
GRQLTIFNSQA I IGG++QG+PFQGQ+SGLYY
Sbjct: 1256 DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 1315
Query: 238 NGLKVLNMAAENDANIAIVGNVRLVGEVPS-SMTTESTATAMQSEMSTSIMETTTTLATS 296
NGLKVL +AAE+D N+ G++RLVGE PS ++ E+TAT + ++M+T+IMETTTT+AT+
Sbjct: 1316 NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 1375
Query: 297 TARRGKPPT-KEPISQTTDDILVASAECPSDDEDIDPCEPSSGG 339
T RRG+ PT ++ +Q TDD+LVASAECPSDDED++ CEPS+GG
Sbjct: 1376 TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGG 1419
Score = 164 bits (416), Expect = 1e-40
Identities = 85/102 (83%), Positives = 91/102 (89%), Gaps = 1/102 (0%)
Query: 341 ANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHV 400
ANPT G R P PG+ EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY V
Sbjct: 1612 ANPTGPGERGP-PGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 1670
Query: 401 DESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
D+SRNYISNSAQSNGAVVKEK P++ K+ +K KKNKDKEYYV
Sbjct: 1671 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 1712
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/175 (24%), Positives = 71/175 (40%), Gaps = 34/175 (19%)
Query: 115 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTD--DIAIEESNAII 172
D + + F T+Q+ +++ S+ DY+ L + G + + N+G+ + +E N
Sbjct: 312 DEITLAFRTLQRNGLMLHTGKSA---DYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKF 368
Query: 173 NDGKYHVVRFTRS------GGNA---------TLQVDSWPVIERYPAGRQLTIFNSQATI 217
ND +H VR TR+ G+A T+ VD Y T+ S
Sbjct: 369 NDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGY-TQEDYTMLGSDDFF 427
Query: 218 IIGGKEQ-----GQP----FQGQLSGLYYNG----LKVLNMAAENDANIAIVGNV 259
IGG G P F G L + Y L++ +A E D + + G++
Sbjct: 428 YIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQGDL 482
Score = 37.0 bits (84), Expect = 0.036
Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 15/152 (9%)
Query: 112 TRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
T A+ +++ F + Q+ L+ +S D L L + G++ + N+ + S
Sbjct: 751 TEAEDVSLRFMS-QRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPSKGP 809
Query: 172 --------INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTI-FNSQATIIIGGK 222
+ND ++H VR R G + L VD+ +E AG + + F++ T I+ +
Sbjct: 810 ETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDN-VTVEGQMAGAHMRLEFHNIETGIMTER 868
Query: 223 E----QGQPFQGQLSGLYYNGLKVLNMAAEND 250
F G LSGL +NG ++ + D
Sbjct: 869 RFISVVPSNFIGHLSGLVFNGQPYMDQCKDGD 900
Score = 36.2 bits (82), Expect = 0.061
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Query: 135 SSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVD 194
SS+ DY + + G + + ++G+ I + S+ +NDG++ V F R G ++ V+
Sbjct: 546 SSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKGSISVN 605
Query: 195 SWPVIERYPAGRQLTIFNSQATIIIGGKEQG 225
S + A I + ++ + +GG +G
Sbjct: 606 SRST--PFLATGDSEILDLESELYLGGLPEG 634
Score = 34.7 bits (78), Expect = 0.18
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 117 LAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGK 176
L+ T A+L+ +D G D+LEL + G++ ++F + + A + + + D +
Sbjct: 53 LSFSLRTNATRALLLYLDDG-GDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDR 111
Query: 177 YHVVRFTRSGGNATLQVD 194
+H+V TR L VD
Sbjct: 112 WHMVLLTRDARRTALAVD 129
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
Length = 1331
Score = 63.2 bits (152), Expect = 5e-10
Identities = 75/343 (21%), Positives = 136/343 (39%), Gaps = 71/343 (20%)
Query: 107 NDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQ-GKIGVKFNVG--TDDI 163
N P + + FST + +L+ + SS D+L + + G + +++N+G +
Sbjct: 1041 NSHPDLAQEEIRFSFSTTKAPCILLYI--SSFTTDFLAVLVKPTGSLQIRYNLGGTREPY 1098
Query: 164 AIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGG-- 221
I+ + + +G+ H V TR L++D +P + + T+FNS ++ +G
Sbjct: 1099 NIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVI 1158
Query: 222 ----------KEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTT 271
K F G LS + +N + L AA N + +V + GE+ S
Sbjct: 1159 ETGKIDQEIHKYNTPGFTGCLSRVQFNQIAPLK-AALRQTNAS--AHVHIQGELVESNCG 1215
Query: 272 ESTATAMQSEMSTSIMETTTTLATSTARRGKPPTKEPISQTTDDILVASAECPSDDEDID 331
S P T P+S TD + + S D +
Sbjct: 1216 AS-----------------------------PLTLSPMSSATDPWHLDHLDSASADFPYN 1246
Query: 332 PCEPSSGGLANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYR 391
P G R G + +S+ G V+ +V LC L+ L +Y
Sbjct: 1247 P------GQGQAIRNG-----------VNRNSAIIGGVIAVVIFTILCTLVFLI---RYM 1286
Query: 392 NRDEGSYHVDESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKK 434
R +G+YH +E++ + SA+S A + P+ ++ +++KK
Sbjct: 1287 FRHKGTYHTNEAKG--AESAESADAAIMNNDPNFTETIDESKK 1327
Score = 49.7 bits (117), Expect = 5e-06
Identities = 39/185 (21%), Positives = 81/185 (43%), Gaps = 18/185 (9%)
Query: 107 NDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIA-- 164
N + T D +A+ F T + E V++ + G DY+ L + + K+ + N+G++ +
Sbjct: 202 NKKMKTLKDVIALNFKTSESEGVILHGEGQQG--DYITLELKKAKLVLSLNLGSNQLGPI 259
Query: 165 ----IEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIG 220
+ ++++D +H V R G + L +D ++ + + + I G
Sbjct: 260 YGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDR--SMQHFRTNGEFDYLDLDYEITFG 317
Query: 221 GKE-QGQP-------FQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTE 272
G G+P F+G + + YNG+ + ++A + VGN+ P ++
Sbjct: 318 GIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPVF 377
Query: 273 STATA 277
AT+
Sbjct: 378 FNATS 382
Score = 37.7 bits (86), Expect = 0.021
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 138 GLGDYLELHIHQG-KIGVKFNVGTDDIAIE-ESNAIINDGKYHVVRFTRSGGNATLQVDS 195
G D+++L + ++ F+VG + I S +ND ++H V R+ A+LQVD
Sbjct: 841 GKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDR 900
Query: 196 WPVIERYPAGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGL 240
P R T + + +GG Q F G + L NG+
Sbjct: 901 LPQQIRKAPTEGHTRLELYSQLFVGGAGGQQGFLGCIRSLRMNGV 945
Score = 33.5 bits (75), Expect = 0.40
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 121 FSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEE--SNAIINDGKYH 178
F T +LV + LG+ +E+ + + K+GV N+ ++ + S + +NDG++H
Sbjct: 401 FRTWNPNGLLVFSHFADNLGN-VEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWH 459
Query: 179 VVRFTRSGGNATLQVD 194
VRF A L +D
Sbjct: 460 EVRFLAKENFAILTID 475
>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
Length = 1384
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/233 (23%), Positives = 100/233 (42%), Gaps = 31/233 (13%)
Query: 58 HIHHFHGSSKH-HSVPIAIY-RSPASLRGGHAGTTY----IFSKGGGQITYKWPPNDRPS 111
H HFH ++++ VP+A R LR G G Y ++ G I+Y++P R
Sbjct: 135 HDLHFHFTARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFP---RGV 191
Query: 112 TRA--DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDI------ 163
+R+ D A F T +K+ +L+ + + G DY+ L + + + ++G+ I
Sbjct: 192 SRSLWDVFAFSFKTEEKDGLLLHAEGAQG--DYVTLELEGAHLLLHMSLGSSPIQPRPGH 249
Query: 164 AIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGG-- 221
+ ++ND +H VR R G + +D + ++R+ N + IGG
Sbjct: 250 TTVSAGGVLNDQHWHYVRVDRFGRDVNFTLDGY--VQRFILNGDFERLNLDTEMFIGGLV 307
Query: 222 ------KEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNV--RLVGEVP 266
F+G + + +N + + ++A + I G V R + VP
Sbjct: 308 GAARKNLAYRHNFRGCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVP 360
Score = 43.5 bits (101), Expect = 4e-04
Identities = 47/185 (25%), Positives = 80/185 (43%), Gaps = 32/185 (17%)
Query: 115 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQ-GKIGVKFNVGTDDIAIEESNAIIN 173
+ ++ FST AVL+ V SS + DY+ + I G + +++ +GT + + +
Sbjct: 1082 EEVSFSFSTSSAPAVLLYV--SSFVRDYMAVLIKDDGTLQLRYQLGTSPYVYQLTTRPVT 1139
Query: 174 DGKYHVVRFTRSGGNATLQVDSWPVIE---------RYPAGRQLTIFNSQATIIIGGKEQ 224
DG+ H + TR N +QVD +P+ E + + + L + T +I + Q
Sbjct: 1140 DGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQ 1199
Query: 225 ---GQPFQGQLSGLYYNGLKVLN--------MAAENDANIAIVGNV---------RLVGE 264
F G LSG+ +N + L M AE + + G + RLV E
Sbjct: 1200 RYNTPGFSGCLSGVRFNNVAPLKTHFRTPRPMTAELAEALRVQGELSESNCGAMPRLVSE 1259
Query: 265 VPSSM 269
VP +
Sbjct: 1260 VPPEL 1264
Score = 32.7 bits (73), Expect = 0.68
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 156 FNVGTDD--IAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWP-VIERYPAGRQLTIFN 212
F+VG D + + + ND ++H+VR + A L+VD P V+ P + +
Sbjct: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEY 911
Query: 213 SQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDAN 252
Q + + + +PF G L + NG+ LN+ +A+
Sbjct: 912 DQPLYVGSAELKRRPFVGCLRAMRLNGV-TLNLEGRANAS 950
>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
sapiens]
Length = 1308
Score = 53.1 bits (126), Expect = 5e-07
Identities = 41/169 (24%), Positives = 73/169 (43%), Gaps = 18/169 (10%)
Query: 115 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVG------TDDIAIEES 168
D +++ F T+Q + +L+ + +G D++ L + + ++ + N G T +
Sbjct: 206 DIISLKFKTMQSDGILLHREGPNG--DHITLQLRRARLFLLINSGEAKLPSTSTLVNLTL 263
Query: 169 NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGG-----KE 223
++++D +H V R G VD + A + + N I GG K
Sbjct: 264 GSLLDDQHWHSVLIQRLGKQVNFTVDEHR--HHFHARGEFNLMNLDYEISFGGIPAPGKS 321
Query: 224 QGQP---FQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSM 269
P F G L LYYNG+ ++++A + I +GNV P SM
Sbjct: 322 VSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNVSFSCSQPQSM 370
Score = 38.1 bits (87), Expect = 0.016
Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 7/108 (6%)
Query: 138 GLGDYLELHIHQGKIGV-KFNVGTDDIAIE-ESNAIINDGKYHVVRFTRSGGNATLQVDS 195
G+ D++ + + + F+VG I +S ND ++H VR R+ A+LQVD
Sbjct: 835 GIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQ 894
Query: 196 -WPVIERYPA-GRQLTIFNSQATIIIGGKEQGQ-PFQGQLSGLYYNGL 240
P + PA G L NSQ + +GG Q F G + L NG+
Sbjct: 895 LTPKTQPAPADGHVLLQLNSQ--LFVGGTATRQRGFLGCIRSLQLNGM 940
>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
Length = 1306
Score = 46.2 bits (108), Expect = 6e-05
Identities = 37/163 (22%), Positives = 70/163 (42%), Gaps = 19/163 (11%)
Query: 111 STRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES-- 168
ST D +++ F ++Q + VL + G D++ L + +G++ + N+G + S
Sbjct: 199 STLKDVISLKFKSMQGDGVLFHGEGQRG--DHITLELQKGRLALHLNLGDSKARLSSSLP 256
Query: 169 ----NAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGG-KE 223
++++D +H V R G VD + + + + + GG
Sbjct: 257 SATLGSLLDDQHWHSVLIERVGKQVNFTVDKHT--QHFRTKGETDALDIDYELSFGGIPV 314
Query: 224 QGQP-------FQGQLSGLYYNGLKVLNMAAENDANIAIVGNV 259
G+P F G + LYYNG+ ++++A I GNV
Sbjct: 315 PGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNV 356
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 3/108 (2%)
Query: 138 GLGDYLELHIHQ-GKIGVKFNVGTDDIA-IEESNAIINDGKYHVVRFTRSGGNATLQVDS 195
G+ D++ L I +I +VG + + +S +++ND ++H VR R+ +LQVD+
Sbjct: 833 GIKDFIRLEISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDN 892
Query: 196 WPVIERYPAGRQLTIFNSQATIIIGGKEQGQP-FQGQLSGLYYNGLKV 242
P R + + + +GG Q F G + L+ NG K+
Sbjct: 893 LPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKM 940
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 45.8 bits (107), Expect = 8e-05
Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 20/188 (10%)
Query: 79 PASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSG 138
P+ G G++ + G + Y+ N+ +L + T AV++ +
Sbjct: 3819 PSGRFGQCPGSSSMTLTGNSYVKYRLTENENKLEM--KLTMRLRTYSTHAVVMYARGT-- 3874
Query: 139 LGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPV 198
DY L IH G++ KF+ G+ + + +NDG++H V +G A L +D
Sbjct: 3875 --DYSILEIHHGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHT 3932
Query: 199 IERYPAGRQLTIFNSQATIIIGG------------KEQGQPFQGQLSGLYYNGLKV-LNM 245
G T+ N + GG + G F+G + +Y NG ++ LN
Sbjct: 3933 ASGTAPGTLKTL-NLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNS 3991
Query: 246 AAENDANI 253
+ A+I
Sbjct: 3992 KPRSYAHI 3999
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 42.0 bits (97), Expect = 0.001
Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 19/136 (13%)
Query: 117 LAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGK 176
+ + ST + +L+ +G D++ + ++QG + V ++ G+ + S INDG+
Sbjct: 1190 ITLQVSTAEDNGILLY----NGDNDHIAVELYQGHVRVSYDPGSYPSSAIYSAETINDGQ 1245
Query: 177 YHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKE------------- 223
+H V L +D + G+ T+ NS+A + +GG
Sbjct: 1246 FHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTL-NSEAPLYVGGMPVDVNSAAFRLWQI 1304
Query: 224 -QGQPFQGQLSGLYYN 238
G F G + LY N
Sbjct: 1305 LNGTGFHGCIRNLYIN 1320
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 22/142 (15%)
Query: 121 FSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
F + ++ +R SS G+ D++ L + G++ FNVG + I S
Sbjct: 1482 FGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIR-SQEK 1540
Query: 172 INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQ----- 226
NDG +H V F R + L +D V+E + T + + I +GG G+
Sbjct: 1541 YNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT-WKIKGPIYLGGVAPGKAVKNV 1599
Query: 227 ------PFQGQLSGLYYNGLKV 242
F G LS L NG +
Sbjct: 1600 QINSIYSFSGCLSNLQLNGASI 1621
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 22/142 (15%)
Query: 121 FSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
F + ++ +R SS G+ D++ L + G++ FNVG + I S
Sbjct: 1489 FGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIR-SQEK 1547
Query: 172 INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQ----- 226
NDG +H V F R + L +D V+E + T + + I +GG G+
Sbjct: 1548 YNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT-WKIKGPIYLGGVAPGKAVKNV 1606
Query: 227 ------PFQGQLSGLYYNGLKV 242
F G LS L NG +
Sbjct: 1607 QINSIYSFSGCLSNLQLNGASI 1628
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 22/142 (15%)
Query: 121 FSTVQKEAVLVRVDSSSGL---------GDYLELHIHQGKIGVKFNVGTDDIAIEESNAI 171
F + ++ +R SS G+ D++ L + G++ FNVG + I S
Sbjct: 1482 FGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIR-SQEK 1540
Query: 172 INDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQGQ----- 226
NDG +H V F R + L +D V+E + T + + I +GG G+
Sbjct: 1541 YNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEAT-WKIKGPIYLGGVAPGKAVKNV 1599
Query: 227 ------PFQGQLSGLYYNGLKV 242
F G LS L NG +
Sbjct: 1600 QINSIYSFSGCLSNLQLNGASI 1621
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 40.4 bits (93), Expect = 0.003
Identities = 17/20 (85%), Positives = 17/20 (85%)
Query: 10 AELGSPGGGGGGGGGGGAGG 29
A LGS GGGGGGGGGGG GG
Sbjct: 407 AALGSRGGGGGGGGGGGGGG 426
Score = 35.4 bits (80), Expect = 0.10
Identities = 14/16 (87%), Positives = 14/16 (87%)
Query: 13 GSPGGGGGGGGGGGAG 28
G GGGGGGGGGGGAG
Sbjct: 415 GGGGGGGGGGGGGGAG 430
Score = 35.4 bits (80), Expect = 0.10
Identities = 14/17 (82%), Positives = 14/17 (82%)
Query: 13 GSPGGGGGGGGGGGAGG 29
G GGGGGGGGG GAGG
Sbjct: 417 GGGGGGGGGGGGAGAGG 433
Score = 35.0 bits (79), Expect = 0.14
Identities = 14/21 (66%), Positives = 15/21 (71%)
Query: 9 GAELGSPGGGGGGGGGGGAGG 29
G+ G GGGGGGGGGGG G
Sbjct: 410 GSRGGGGGGGGGGGGGGGGAG 430
Score = 32.3 bits (72), Expect = 0.88
Identities = 14/23 (60%), Positives = 14/23 (60%)
Query: 7 RCGAELGSPGGGGGGGGGGGAGG 29
R G G GGGGGGGG G GG
Sbjct: 412 RGGGGGGGGGGGGGGGGAGAGGG 434
Score = 32.3 bits (72), Expect = 0.88
Identities = 15/33 (45%), Positives = 16/33 (48%)
Query: 13 GSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLL 45
G GGGGGGG G G G P + SG L
Sbjct: 419 GGGGGGGGGGAGAGGGSDFGCSAAAPRSESGFL 451
>gi|8051605 glycophorin C isoform 2 [Homo sapiens]
Length = 109
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/100 (28%), Positives = 56/100 (56%), Gaps = 14/100 (14%)
Query: 350 EPYPGSA---EVIRESSSTTGM----VVGIVAAAALCILILLYAMYKYRNRDEGSYHVDE 402
EP PG + + E+S+ T M + G++AA A+ ++ LL+ M +Y R +G+YH +E
Sbjct: 17 EPDPGMSGWPDGRMETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNE 76
Query: 403 SRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
++ + A+S A + + P+ + + ++ KEY++
Sbjct: 77 AKG--TEFAESADAAL-QGDPALQDAGDSSR----KEYFI 109
>gi|4504229 glycophorin C isoform 1 [Homo sapiens]
Length = 128
Score = 40.4 bits (93), Expect = 0.003
Identities = 28/100 (28%), Positives = 56/100 (56%), Gaps = 14/100 (14%)
Query: 350 EPYPGSA---EVIRESSSTTGM----VVGIVAAAALCILILLYAMYKYRNRDEGSYHVDE 402
EP PG + + E+S+ T M + G++AA A+ ++ LL+ M +Y R +G+YH +E
Sbjct: 36 EPDPGMSGWPDGRMETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNE 95
Query: 403 SRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442
++ + A+S A + + P+ + + ++ KEY++
Sbjct: 96 AKG--TEFAESADAAL-QGDPALQDAGDSSR----KEYFI 128
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 40.0 bits (92), Expect = 0.004
Identities = 20/81 (24%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Query: 141 DYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIE 200
D++ L + G + ++ +G+ + + + I NDG++H V R G ++QVD ++
Sbjct: 4258 DFISLGLQDGHLVFRYQLGSGEARLVSEDPI-NDGEWHRVTALREGRRGSIQVDGEELVS 4316
Query: 201 RYPAGRQLTIFNSQATIIIGG 221
G + + N++ ++ IGG
Sbjct: 4317 GRSPGPNVAV-NAKGSVYIGG 4336
>gi|33469931 EGF-like, fibronectin type III and laminin G domains
isoform 2 [Homo sapiens]
Length = 775
Score = 40.0 bits (92), Expect = 0.004
Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Query: 111 STRADRLAIGFSTVQKEAVLVRV-DSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESN 169
S +A ++ + F ++ +L+ ++ G GD++ L I + + +FN GT +AI S
Sbjct: 171 SYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGT-GVAIIVSE 229
Query: 170 AIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQ----- 224
I G +H V R G N LQ+++ + G Q + + + +GG
Sbjct: 230 TKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQG-QYSKITFRTPLYLGGAPSAYWLV 288
Query: 225 -----GQPFQGQLSGLYYNGLKV 242
+ FQG + L NG ++
Sbjct: 289 RATGTNRGFQGCVQSLAVNGRRI 311
Score = 38.5 bits (88), Expect = 0.012
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 137 SGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSW 196
+G D+L +++ G + +F+ G+ + S + G +H +R +R+ N LQVD
Sbjct: 422 TGSKDFLSINLAGGHVEFRFDCGSGT-GVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQ 480
Query: 197 PVIERYPAGRQLTIFNSQATIIIGG--------KEQG--QPFQGQLSGLYYN 238
++E G T I IGG K G +PF G + + N
Sbjct: 481 KIVEGMAEG-GFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILN 531
Score = 38.1 bits (87), Expect = 0.016
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 96 GGGQITYKWPPN-DRPSTRADRLAIGFSTVQKEAVLV-RVDSSSGLG-DYLELHIHQGKI 152
G +TY P R S + + F T K+ +L+ R DS D++ L + G +
Sbjct: 600 GRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGAL 659
Query: 153 GVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAG--RQLTI 210
+N+G+ +A N NDG++H V+ R G + + VD + G RQL
Sbjct: 660 VFSYNLGSG-VASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQL-- 716
Query: 211 FNSQATIIIGGKEQ 224
N + +GG ++
Sbjct: 717 -NINGALYVGGMKE 729
>gi|33469929 EGF-like, fibronectin type III and laminin G domains
isoform 1 [Homo sapiens]
Length = 1009
Score = 40.0 bits (92), Expect = 0.004
Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 13/143 (9%)
Query: 111 STRADRLAIGFSTVQKEAVLVRV-DSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESN 169
S +A ++ + F ++ +L+ ++ G GD++ L I + + +FN GT +AI S
Sbjct: 405 SYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGT-GVAIIVSE 463
Query: 170 AIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIGGKEQ----- 224
I G +H V R G N LQ+++ + G Q + + + +GG
Sbjct: 464 TKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQG-QYSKITFRTPLYLGGAPSAYWLV 522
Query: 225 -----GQPFQGQLSGLYYNGLKV 242
+ FQG + L NG ++
Sbjct: 523 RATGTNRGFQGCVQSLAVNGRRI 545
Score = 38.5 bits (88), Expect = 0.012
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 137 SGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSW 196
+G D+L +++ G + +F+ G+ + S + G +H +R +R+ N LQVD
Sbjct: 656 TGSKDFLSINLAGGHVEFRFDCGSGT-GVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQ 714
Query: 197 PVIERYPAGRQLTIFNSQATIIIGG--------KEQG--QPFQGQLSGLYYN 238
++E G T I IGG K G +PF G + + N
Sbjct: 715 KIVEGMAEG-GFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILN 765
Score = 38.1 bits (87), Expect = 0.016
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 96 GGGQITYKWPPN-DRPSTRADRLAIGFSTVQKEAVLV-RVDSSSGLG-DYLELHIHQGKI 152
G +TY P R S + + F T K+ +L+ R DS D++ L + G +
Sbjct: 834 GRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGAL 893
Query: 153 GVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAG--RQLTI 210
+N+G+ +A N NDG++H V+ R G + + VD + G RQL
Sbjct: 894 VFSYNLGSG-VASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQL-- 950
Query: 211 FNSQATIIIGGKEQ 224
N + +GG ++
Sbjct: 951 -NINGALYVGGMKE 963
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 39.7 bits (91), Expect = 0.006
Identities = 16/22 (72%), Positives = 16/22 (72%)
Query: 8 CGAELGSPGGGGGGGGGGGAGG 29
CG G GGGGGGGGGGG GG
Sbjct: 450 CGGGGGGGGGGGGGGGGGGGGG 471
Score = 36.2 bits (82), Expect = 0.061
Identities = 14/17 (82%), Positives = 14/17 (82%)
Query: 13 GSPGGGGGGGGGGGAGG 29
G GGGGGGGGGGG GG
Sbjct: 456 GGGGGGGGGGGGGGGGG 472
Score = 36.2 bits (82), Expect = 0.061
Identities = 14/17 (82%), Positives = 14/17 (82%)
Query: 13 GSPGGGGGGGGGGGAGG 29
G GGGGGGGGGGG GG
Sbjct: 457 GGGGGGGGGGGGGGGGG 473
Score = 35.8 bits (81), Expect = 0.080
Identities = 15/21 (71%), Positives = 15/21 (71%)
Query: 9 GAELGSPGGGGGGGGGGGAGG 29
G G GGGGGGGGGGG GG
Sbjct: 444 GQLYGPCGGGGGGGGGGGGGG 464
Score = 35.0 bits (79), Expect = 0.14
Identities = 14/20 (70%), Positives = 15/20 (75%)
Query: 13 GSPGGGGGGGGGGGAGGRLA 32
G GGGGGGGGGGG G +A
Sbjct: 460 GGGGGGGGGGGGGGEAGAVA 479
>gi|5032007 purine-rich element binding protein A [Homo sapiens]
Length = 322
Score = 39.3 bits (90), Expect = 0.007
Identities = 16/21 (76%), Positives = 18/21 (85%)
Query: 9 GAELGSPGGGGGGGGGGGAGG 29
G+ GS GGGGGGGGGGG+GG
Sbjct: 25 GSGSGSGGGGGGGGGGGGSGG 45
Score = 36.6 bits (83), Expect = 0.047
Identities = 15/24 (62%), Positives = 15/24 (62%)
Query: 6 LRCGAELGSPGGGGGGGGGGGAGG 29
L G LG PG G G GGGGG GG
Sbjct: 15 LGSGGSLGHPGSGSGSGGGGGGGG 38
Score = 35.0 bits (79), Expect = 0.14
Identities = 14/21 (66%), Positives = 15/21 (71%)
Query: 9 GAELGSPGGGGGGGGGGGAGG 29
G+ G GGGGGGGGG G GG
Sbjct: 27 GSGSGGGGGGGGGGGGSGGGG 47
Score = 34.3 bits (77), Expect = 0.23
Identities = 14/21 (66%), Positives = 15/21 (71%)
Query: 9 GAELGSPGGGGGGGGGGGAGG 29
G+ G GGGGGGG GGG GG
Sbjct: 29 GSGGGGGGGGGGGGSGGGGGG 49
Score = 33.1 bits (74), Expect = 0.52
Identities = 14/19 (73%), Positives = 14/19 (73%)
Query: 13 GSPGGGGGGGGGGGAGGRL 31
G GGGG GGGGGGA G L
Sbjct: 36 GGGGGGGSGGGGGGAPGGL 54
>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
isoform b [Homo sapiens]
Length = 373
Score = 39.3 bits (90), Expect = 0.007
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 13/96 (13%)
Query: 7 RCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSS 66
R +L + G G G GG+G + V +S ++ A S G H+ HH H ++
Sbjct: 133 RGAQQLAAAAGAGAGASLGGSGEEMGPAAAV---VSAVIAAAAAQSGAGPHYHHHHHHAA 189
Query: 67 KHHSVPIA----IYRSPASLRGGHAGTTYIFSKGGG 98
HH P A S A+ GG G GGG
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGA------GGG 219
Score = 36.6 bits (83), Expect = 0.047
Identities = 15/20 (75%), Positives = 15/20 (75%)
Query: 10 AELGSPGGGGGGGGGGGAGG 29
A G GGGGGGGGGGGA G
Sbjct: 222 ASAGGGGGGGGGGGGGGAAG 241
Score = 36.2 bits (82), Expect = 0.061
Identities = 15/21 (71%), Positives = 15/21 (71%)
Query: 9 GAELGSPGGGGGGGGGGGAGG 29
G S GGGGGGGGGGG GG
Sbjct: 218 GGGPASAGGGGGGGGGGGGGG 238
Score = 35.4 bits (80), Expect = 0.10
Identities = 24/56 (42%), Positives = 24/56 (42%), Gaps = 17/56 (30%)
Query: 9 GAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHG 64
GA G P GGGGGGGG GG G A GA GA H HH G
Sbjct: 215 GAGGGGPASAGGGGGGGGGGGG---------------GGAAGAG--GALHPHHAAG 253
>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
isoform a [Homo sapiens]
Length = 403
Score = 39.3 bits (90), Expect = 0.007
Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 13/96 (13%)
Query: 7 RCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHGSS 66
R +L + G G G GG+G + V +S ++ A S G H+ HH H ++
Sbjct: 133 RGAQQLAAAAGAGAGASLGGSGEEMGPAAAV---VSAVIAAAAAQSGAGPHYHHHHHHAA 189
Query: 67 KHHSVPIA----IYRSPASLRGGHAGTTYIFSKGGG 98
HH P A S A+ GG G GGG
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGA------GGG 219
Score = 36.6 bits (83), Expect = 0.047
Identities = 15/20 (75%), Positives = 15/20 (75%)
Query: 10 AELGSPGGGGGGGGGGGAGG 29
A G GGGGGGGGGGGA G
Sbjct: 222 ASAGGGGGGGGGGGGGGAAG 241
Score = 36.2 bits (82), Expect = 0.061
Identities = 15/21 (71%), Positives = 15/21 (71%)
Query: 9 GAELGSPGGGGGGGGGGGAGG 29
G S GGGGGGGGGGG GG
Sbjct: 218 GGGPASAGGGGGGGGGGGGGG 238
Score = 35.4 bits (80), Expect = 0.10
Identities = 24/56 (42%), Positives = 24/56 (42%), Gaps = 17/56 (30%)
Query: 9 GAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIHHFHG 64
GA G P GGGGGGGG GG G A GA GA H HH G
Sbjct: 215 GAGGGGPASAGGGGGGGGGGGG---------------GGAAGAG--GALHPHHAAG 253
>gi|154091020 leucine-rich repeats and calponin homology (CH)
domain containing 2 [Homo sapiens]
Length = 765
Score = 39.3 bits (90), Expect = 0.007
Identities = 23/50 (46%), Positives = 27/50 (54%), Gaps = 4/50 (8%)
Query: 13 GSPGGGGGGGGGGGAGGRLALLWIVPL-TLSGL---LGVAWGASSLGAHH 58
G+ GGGGGG GGGG GG L+ +P+ TL G G W SL H
Sbjct: 26 GTAGGGGGGAGGGGGGGGGTLVVPIPVPTLFGQPFPNGPPWNPGSLQPQH 75
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 39.3 bits (90), Expect = 0.007
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 8/136 (5%)
Query: 62 FHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGF 121
F+G S V P + G H S G +++Y P+ P+ + + + F
Sbjct: 3948 FNGGSCQSGVDSYYCHCPFGVFGKHCELN---SYGFEELSYMEFPSLDPNN--NYIYVKF 4002
Query: 122 STVQKEAVLV-RVDSSSG-LGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKYHV 179
+T++ A+L+ D+ +G ++L L I + ++ +N+G+ + + +DG +H
Sbjct: 4003 ATIKSHALLLYNYDNQTGDRAEFLALEIAEERLRFSYNLGSGTYKLTTMKKV-SDGHFHT 4061
Query: 180 VRFTRSGGNATLQVDS 195
V R+G A+L VDS
Sbjct: 4062 VIARRAGMAASLTVDS 4077
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,574,546
Number of Sequences: 37866
Number of extensions: 858436
Number of successful extensions: 14316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 8055
Number of HSP's gapped (non-prelim): 3667
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.