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Search of human proteins with 210147453
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|210147453 nuclear localized factor 3 [Homo sapiens]
(421 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|210147453 nuclear localized factor 3 [Homo sapiens] 834 0.0
gi|157278361 nuclear localized factor 2 [Homo sapiens] 167 2e-41
gi|209862787 hypothetical protein LOC100191040 [Homo sapiens] 159 6e-39
gi|147903292 nuclear localized factor 1 [Homo sapiens] 157 2e-38
gi|14249614 synaptotagmin-like 1 [Homo sapiens] 60 4e-09
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 56 5e-08
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 56 5e-08
gi|123173752 synaptotagmin XIV-like [Homo sapiens] 49 7e-06
gi|45387945 family with sequence similarity 62 (C2 domain contai... 45 9e-05
gi|6005997 double C2-like domains, beta [Homo sapiens] 45 2e-04
gi|57864582 hornerin [Homo sapiens] 42 8e-04
gi|47078261 double C2-like domains, alpha [Homo sapiens] 42 8e-04
gi|4503431 dysferlin isoform 8 [Homo sapiens] 41 0.002
gi|195976764 dysferlin isoform 14 [Homo sapiens] 41 0.002
gi|195976762 dysferlin isoform 13 [Homo sapiens] 41 0.002
gi|195976760 dysferlin isoform 12 [Homo sapiens] 41 0.002
gi|195976758 dysferlin isoform 11 [Homo sapiens] 41 0.002
gi|195976756 dysferlin isoform 10 [Homo sapiens] 41 0.002
gi|195976754 dysferlin isoform 9 [Homo sapiens] 41 0.002
gi|24308219 synaptotagmin IV [Homo sapiens] 41 0.002
gi|216548478 synaptotagmin XI [Homo sapiens] 41 0.002
gi|12545408 RAS p21 protein activator 2 [Homo sapiens] 40 0.005
gi|11386161 alpha 2 type IX collagen [Homo sapiens] 39 0.007
gi|153792074 proline rich 12 [Homo sapiens] 39 0.007
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 39 0.009
gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens] 39 0.009
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi... 39 0.009
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 39 0.012
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 38 0.015
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 38 0.015
>gi|210147453 nuclear localized factor 3 [Homo sapiens]
Length = 421
Score = 834 bits (2154), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP 60
MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP
Sbjct: 1 MRKTNMWFLERLRGSGENGAARGVGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGP 60
Query: 61 AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW 120
AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW
Sbjct: 61 AEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDW 120
Query: 121 LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG 180
LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG
Sbjct: 121 LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPG 180
Query: 181 AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK 240
AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK
Sbjct: 181 AGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLLK 240
Query: 241 GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT 300
GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT
Sbjct: 241 GFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHT 300
Query: 301 VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS 360
VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS
Sbjct: 301 VHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRS 360
Query: 361 TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPF 420
TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPF
Sbjct: 361 TIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLPF 420
Query: 421 L 421
L
Sbjct: 421 L 421
>gi|157278361 nuclear localized factor 2 [Homo sapiens]
Length = 364
Score = 167 bits (423), Expect = 2e-41
Identities = 144/410 (35%), Positives = 195/410 (47%), Gaps = 74/410 (18%)
Query: 26 SEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQ 85
S AG A K P ++ VLTP++IP+F IPP+LP+ P T E + +AA
Sbjct: 10 SAAGSSAPK-PAFAKVLTPNRIPEFCIPPRLPA------------PCTLESPIRAAA--- 53
Query: 86 TPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDWLSEEA--TDADPQAQGAMSLPSVPK 143
+P + AAES +AA E+A TD DP++Q A+SLP +P+
Sbjct: 54 ------VPRRCAAESDLWPRAA--------------DEDAGRTDWDPRSQAALSLPHLPR 93
Query: 144 AQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGA 203
+T+YGF L ESPHTRRKESL +G P A R R A + GG GGP G
Sbjct: 94 VRTTYGFCALLESPHTRRKESLL---------LGGPPAPRPR--AHSCGGGGGPDAPLGT 142
Query: 204 LMSP------GRYFSGGESDTGSSAESSP-------FGSPLLSRSVSLLKGFAQDSQAKV 250
L P GG + + P LLSR++ + V
Sbjct: 143 LCGPRGPGPATPAAPGGPRLPQDALAAGPRRCRLLRVPDGLLSRALRAGRSRRLARVRSV 202
Query: 251 SQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARGEHTVHVGPRG-SV 309
S R + P +SP S R P PE +A+G TV +G G ++
Sbjct: 203 SSGNEDEERRAGSESPARAPSSSPLSSR--------APLPERLEAKG--TVALGRAGDAL 252
Query: 310 RLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCL-VPGKLQKQRSTIVKNSRR 368
RL AEY G RLR+ LL AE L+ R++ C + L L PG + Q S +V SR+
Sbjct: 253 RLAAEYCPGTRRLRLRLLRAESLFGGAPGPRAVRCRLSLVLRPPGTARWQCSAVVGRSRK 312
Query: 369 PVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
F++DF FDGL VR+LA+R+K ++G R LLG+ EL L +LL
Sbjct: 313 ASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRDRGRLLGQGELSLGALL 362
>gi|209862787 hypothetical protein LOC100191040 [Homo sapiens]
Length = 353
Score = 159 bits (401), Expect = 6e-39
Identities = 146/429 (34%), Positives = 187/429 (43%), Gaps = 110/429 (25%)
Query: 6 MWFLERLR---GSGENGAARGVGSEAGDKASKGPLYS---NVLTPDKIPDFFIPPKLPSG 59
MW LE+ G+ E A + + GP S NVLTPD+IP FFIPP+LP
Sbjct: 1 MWLLEKAGYKVGAAEPAARWAPSGLFSKRRAPGPPTSACPNVLTPDRIPQFFIPPRLPDP 60
Query: 60 PAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAED 119
A P AA RHV
Sbjct: 61 -------------------GGAVP----------------------AARRHVA------- 72
Query: 120 WLSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSP 179
+G + S+P G+A L ESPHTRR+ESLFH A A G P
Sbjct: 73 ------------GRGLPATCSLPHLAGREGWAFLPESPHTRRRESLFHGPPPAPAG-GLP 119
Query: 180 GAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVSLL 239
A R + + R +SDT SS +SSPFGSP
Sbjct: 120 AAQSRLHVSAPDL----------------RLCRAPDSDTASSPDSSPFGSP--------- 154
Query: 240 KGFAQDSQAKVSQLRHSVGRHGSLSADD-STPDASPGSRRRLTRRAPPEPGPE----SGQ 294
+ R V R SLS + S+ D SP S RR PP + +
Sbjct: 155 ---------RPGLGRRRVSRPHSLSPEKASSADTSPHSPRRAGPPTPPLFHLDFLCCQLR 205
Query: 295 ARGEHTVHVGPRGS-VRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSIN--CCVGLCLV 351
E + +GPRG +RL EY+AG RLR+ L++AEGL S CCV L L
Sbjct: 206 PTRESVLRLGPRGGQLRLSTEYQAGPGRLRLRLVSAEGLPRPRSRPGSGGGGCCVVLRLR 265
Query: 352 PG-KLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEK 410
P + ++Q+S +VK S P+FNEDFFFDGLGP + +LR KV+++G+ L+RD LLGE
Sbjct: 266 PRVRPREQQSRVVKCSANPIFNEDFFFDGLGPPDLAARSLRAKVLDRGAGLRRDVLLGEC 325
Query: 411 ELPLTSLLP 419
E PL +LLP
Sbjct: 326 ETPLIALLP 334
>gi|147903292 nuclear localized factor 1 [Homo sapiens]
Length = 369
Score = 157 bits (396), Expect = 2e-38
Identities = 146/428 (34%), Positives = 193/428 (45%), Gaps = 76/428 (17%)
Query: 6 MWFLERLRGSGENGAARG----VGSEAGDKASKGPLYSNVLTPDKIPDFFIPPKLPSGPA 61
MW LERLR E G G G K+ +NVLTPD+IP+F IPP+L
Sbjct: 1 MWCLERLRLGPECLRRSGDWLLPGRARGAKSRTTAACANVLTPDRIPEFCIPPRLMP--- 57
Query: 62 EGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQIESAEDWL 121
LA AA R + E + + A R
Sbjct: 58 ---------------RLALAALRNS----------WVEEAGMDEGAGR------------ 80
Query: 122 SEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGALAQVGSPGA 181
TD DP++Q A+SLP +P+ +T+YGF L ESPHTRRKESL +G P A
Sbjct: 81 ----TDWDPRSQAALSLPHLPRVRTAYGFCALLESPHTRRKESLL---------LGGPPA 127
Query: 182 GRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTG------SSAESSPFGSPLLSRS 235
R RA GG GGP G L P + G + P G LL
Sbjct: 128 PRPRA--HTYGGGGGPDALLGTLRVPRAPGPATPAAPGCPRPPQDALARRPRGCRLLRVP 185
Query: 236 VSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPE---PGPES 292
LL + +++ R + R S +D A S R +PP P PE
Sbjct: 186 DGLLSRALRAGRSR----RLTRVRSVSSGNEDKERRAGSQSPARAPSTSPPSSRVPFPER 241
Query: 293 GQARGEHTVHVGPRG-SVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCL- 350
+A G TV +G G ++RL AEY G RLR+ LL AE R+++C + L L
Sbjct: 242 LEAEG--TVALGRAGDALRLAAEYCPGTGRLRLRLLRAESPAGGAPGPRAVSCRLSLVLR 299
Query: 351 VPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEK 410
PG +Q ST+V SR+ F++DF FDGL VR+LA+R+K ++G +R LLG+
Sbjct: 300 PPGTALRQCSTVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRERGRLLGQG 359
Query: 411 ELPLTSLL 418
EL L +LL
Sbjct: 360 ELSLGALL 367
>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
Length = 550
Score = 60.1 bits (144), Expect = 4e-09
Identities = 68/262 (25%), Positives = 100/262 (38%), Gaps = 47/262 (17%)
Query: 155 ESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGG 214
E+P R +E+ A PG G ++ A+ + P G P + +
Sbjct: 143 EAPQERLRETEASDPEEASQAQEDPGQGDQQVCAEEADPELEPASGGEQEPRPQQAQTKA 202
Query: 215 ESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSV--GRHGSLSADDSTPDA 272
S + E +P P L R +S S + VS L S G SLS D
Sbjct: 203 ASQILENGEEAPGPDPSLDRMLS--------SSSSVSSLNSSTLSGSQMSLSGDAEA--- 251
Query: 273 SPGSRRRLTRRAPPEPGPESGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGL 332
V RGSV YE G A LRVH++ +GL
Sbjct: 252 ------------------------------VQVRGSVHFALHYEPGAAELRVHVIQCQGL 281
Query: 333 YDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRI 392
R + V L+P K K+++ + K + PVFNE + + A ++ L +
Sbjct: 282 --AAARRRRSDPYVKSYLLPDKQSKRKTAVKKRNLNPVFNETLRY-SVPQAELQGRVLSL 338
Query: 393 KVVNKGSSLKRDTLLGEKELPL 414
V ++ SL R+ LGE E+PL
Sbjct: 339 SVWHR-ESLGRNIFLGEVEVPL 359
Score = 40.0 bits (92), Expect = 0.004
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 339 ARSINCCVGLCLVPGKLQ--KQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVN 396
A S++ V ++P Q +QR+ +V+ S PVFN +DG GPA +R+ + + +
Sbjct: 427 AGSLDTYVQCFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGFGPADLRQACAELSLWD 486
Query: 397 KGSSLKRDTLLGEKELPL 414
G+ R LG L L
Sbjct: 487 HGALANRQ--LGGTRLSL 502
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 56.2 bits (134), Expect = 5e-08
Identities = 83/371 (22%), Positives = 139/371 (37%), Gaps = 63/371 (16%)
Query: 54 PKLPS-GPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVI 112
PK P+ PA G+ + GP ++AP + P P + A+E++ + +++R
Sbjct: 194 PKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGP--PVRRASEAR--MSSSSR--- 246
Query: 113 QIESAEDW-LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHG 171
+E W S A D+ G SV ++ + G P
Sbjct: 247 ---DSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQP------------ 291
Query: 172 ALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPL 231
Q G+PG R D P A PG E TG G P
Sbjct: 292 --GQPGTPGGSRPGPGPAGRFPDQKPEVAPS---DPGTTAPPREERTGGVG-----GYPA 341
Query: 232 LSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPE 291
+ A+ ++ H G + SA P A+ R PP P E
Sbjct: 342 VG--------------AREDRMSHPSGPYSQASAAAPQPAAA---------RQPPPPEEE 378
Query: 292 SGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSI-NCCVGLCL 350
+A + G++ Y+ + L+ ++ A+GL + D+ + + V L L
Sbjct: 379 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGL--KPMDSNGLADPYVKLHL 436
Query: 351 VPG--KLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLG 408
+PG K K R+ ++N+R P++NE + G+ +++ LRI V ++ + +G
Sbjct: 437 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE-DKFGHNEFIG 495
Query: 409 EKELPLTSLLP 419
E L L P
Sbjct: 496 ETRFSLKKLKP 506
Score = 33.5 bits (75), Expect = 0.37
Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 13/126 (10%)
Query: 280 LTRRAPPEPGPESGQARG---------EHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAE 330
L R P + +G ARG E + RG + + Y Q L V ++
Sbjct: 516 LERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCV 575
Query: 331 GLYDRLCDARSINCCVGLCLVP--GKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKL 388
L + S + V L L P GK K ++ I K + P FNE+FF+D + + + K
Sbjct: 576 HLAAMDANGYS-DPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKK 633
Query: 389 ALRIKV 394
+L I V
Sbjct: 634 SLDISV 639
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 56.2 bits (134), Expect = 5e-08
Identities = 83/371 (22%), Positives = 139/371 (37%), Gaps = 63/371 (16%)
Query: 54 PKLPS-GPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVI 112
PK P+ PA G+ + GP ++AP + P P + A+E++ + +++R
Sbjct: 190 PKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGP--PVRRASEAR--MSSSSR--- 242
Query: 113 QIESAEDW-LSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHG 171
+E W S A D+ G SV ++ + G P
Sbjct: 243 ---DSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQP------------ 287
Query: 172 ALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPL 231
Q G+PG R D P A PG E TG G P
Sbjct: 288 --GQPGTPGGSRPGPGPAGRFPDQKPEVAPS---DPGTTAPPREERTGGVG-----GYPA 337
Query: 232 LSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPE 291
+ A+ ++ H G + SA P A+ R PP P E
Sbjct: 338 VG--------------AREDRMSHPSGPYSQASAAAPQPAAA---------RQPPPPEEE 374
Query: 292 SGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSI-NCCVGLCL 350
+A + G++ Y+ + L+ ++ A+GL + D+ + + V L L
Sbjct: 375 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGL--KPMDSNGLADPYVKLHL 432
Query: 351 VPG--KLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLG 408
+PG K K R+ ++N+R P++NE + G+ +++ LRI V ++ + +G
Sbjct: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE-DKFGHNEFIG 491
Query: 409 EKELPLTSLLP 419
E L L P
Sbjct: 492 ETRFSLKKLKP 502
Score = 33.5 bits (75), Expect = 0.37
Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 13/126 (10%)
Query: 280 LTRRAPPEPGPESGQARG---------EHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAE 330
L R P + +G ARG E + RG + + Y Q L V ++
Sbjct: 512 LERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCV 571
Query: 331 GLYDRLCDARSINCCVGLCLVP--GKLQKQRSTIVKNSRRPVFNEDFFFDGLGPASVRKL 388
L + S + V L L P GK K ++ I K + P FNE+FF+D + + + K
Sbjct: 572 HLAAMDANGYS-DPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKK 629
Query: 389 ALRIKV 394
+L I V
Sbjct: 630 SLDISV 635
>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
Length = 645
Score = 49.3 bits (116), Expect = 7e-06
Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
Query: 307 GSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCC-VGLCLVPGKLQKQRSTIVKN 365
G + ++ EY A +L V ++ A+GL D+ D +N V + L+PGK + R T ++
Sbjct: 352 GDLDVIFEYRAASQKLTVTIVRAQGLPDK--DRSGVNSWQVHVVLLPGKKHRGR-TNIQR 408
Query: 366 SRRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLP 419
PVF E F L P V A+R ++ + R+ ++GEK L+ L P
Sbjct: 409 GPNPVFREKVTFAKLEPRDVAACAVRFRLY-AARKMTRERMMGEKLFYLSHLHP 461
>gi|45387945 family with sequence similarity 62 (C2 domain
containing) member B [Homo sapiens]
Length = 893
Score = 45.4 bits (106), Expect = 9e-05
Identities = 68/259 (26%), Positives = 108/259 (41%), Gaps = 37/259 (14%)
Query: 169 EHGALAQVGSPGA---GRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTG-----S 220
+H AQV P GR+ + G GP GG+ +P GG G
Sbjct: 637 DHQHSAQVKRPSVSKEGRKTSIKSHMSGSPGP---GGSNTAPSTPVIGGSDKPGMEEKAQ 693
Query: 221 SAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRL 280
E+ P G L RS S L A V + S+ ++D S P A+ R+RL
Sbjct: 694 PPEAGPQGLHDLGRSSSSL--LASPGHISVKEPTPSI------ASDISLPIATQELRQRL 745
Query: 281 TRRAPPEPGPESGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDAR 340
+ E+G G+ P G ++L + + + +L V + A L D
Sbjct: 746 RQL-------ENGTTLGQ-----SPLGQIQLTIRHSSQRNKLIVVVHACRNLIAFSEDGS 793
Query: 341 SINCCVGLCLVPGKLQ--KQRSTIVKNSRRPVFNEDFFFDGLGPASVRKLALRIKVVNKG 398
+ V + L+P K + ++++ + K + PVF++ F F P V++ L + V N G
Sbjct: 794 --DPYVRMYLLPDKRRSGRRKTHVSKKTLNPVFDQSFDFSVSLP-EVQRRTLDVAVKNSG 850
Query: 399 SSLKRDT-LLGEKELPLTS 416
L +D LLG+ + L S
Sbjct: 851 GFLSKDKGLLGKVLVALAS 869
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 44.7 bits (104), Expect = 2e-04
Identities = 42/158 (26%), Positives = 68/158 (43%), Gaps = 15/158 (9%)
Query: 268 STPDASPGSRRRLTRRAPPEPGPESGQARGEHTVHVGPRGSVRLLAEYEAGQARLRVHLL 327
S+P SPG PPE P+ A G + G++ Y+ L +
Sbjct: 92 SSPGPSPGPSPARPPAKPPEDEPD---ADGYESDDCTALGTLDFSLLYDQENNALHCTIT 148
Query: 328 AAEGL----YDRLCDARSINCCVGLCLVPG--KLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
A+GL ++ L D V L L+PG K K R+ ++N+ P +NE + G+
Sbjct: 149 KAKGLKPMDHNGLADPY-----VKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGIT 203
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLP 419
+ + LRI V ++ + + +GE +PL L P
Sbjct: 204 DEDMIRKTLRISVCDE-DKFRHNEFIGETRVPLKKLKP 240
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 42.4 bits (98), Expect = 8e-04
Identities = 40/154 (25%), Positives = 56/154 (36%), Gaps = 11/154 (7%)
Query: 162 KESLFHSEHGA-LAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTG- 219
++SL HS HG+ Q SP GR + ++ + G G S G Y SG +G
Sbjct: 525 RQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGL 584
Query: 220 -----SSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASP 274
S +SS +G S S G S S G+HG+ S S+
Sbjct: 585 GHQESRSGQSSGYGQHGSSSGHSSTHG----QHGSTSGQSSSCGQHGATSGQSSSHGQHG 640
Query: 275 GSRRRLTRRAPPEPGPESGQARGEHTVHVGPRGS 308
+ +R G +RG H G S
Sbjct: 641 SGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSS 674
Score = 36.6 bits (83), Expect = 0.044
Identities = 30/109 (27%), Positives = 42/109 (38%), Gaps = 12/109 (11%)
Query: 162 KESLFHSEHGA-LAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGS 220
++SL H +HG+ Q SP GR + + + G R G S G Y SG +G
Sbjct: 991 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGL 1050
Query: 221 SAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDST 269
S G G+ Q + H G+HGS S S+
Sbjct: 1051 GHRESRSGQS---------SGYGQHGSSSGHSSTH--GQHGSTSGQSSS 1088
Score = 35.0 bits (79), Expect = 0.13
Identities = 36/150 (24%), Positives = 52/150 (34%), Gaps = 9/150 (6%)
Query: 167 HSEHGALA----QVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSA 222
H +HG+ + G GA ++++ G G + +G G S G GS +
Sbjct: 1076 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1135
Query: 223 ESSP----FGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRR 278
SP GS S S G + S G+ S S S S G +
Sbjct: 1136 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1195
Query: 279 RLTRRAPPEPGPESGQARGEHTVHVGPRGS 308
+R G G + G + H G GS
Sbjct: 1196 HGSRSGQSSRGERHGSSSGSSS-HYGQHGS 1224
Score = 35.0 bits (79), Expect = 0.13
Identities = 36/150 (24%), Positives = 52/150 (34%), Gaps = 9/150 (6%)
Query: 167 HSEHGALA----QVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSA 222
H +HG+ + G GA ++++ G G + +G G S G GS +
Sbjct: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 223 ESSP----FGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRR 278
SP GS S S G + S G+ S S S S G +
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
Query: 279 RLTRRAPPEPGPESGQARGEHTVHVGPRGS 308
+R G G + G + H G GS
Sbjct: 2606 HGSRSGQSSRGERHGSSSGSSS-HYGQHGS 2634
Score = 33.9 bits (76), Expect = 0.28
Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 12/109 (11%)
Query: 162 KESLFHSEHGA-LAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGS 220
++SL H +HG+ Q SP GR + + + G G S G Y SG +G
Sbjct: 1931 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGL 1990
Query: 221 SAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDST 269
S G G+ Q + H G+HGS S S+
Sbjct: 1991 GHRESRSGQS---------SGYGQHGSSSGHSSTH--GQHGSASGQSSS 2028
Score = 32.7 bits (73), Expect = 0.63
Identities = 39/147 (26%), Positives = 53/147 (36%), Gaps = 20/147 (13%)
Query: 168 SEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSG-------GESDTGS 220
S G+ + G G+G R+++ G G G S GR+ SG G+ +GS
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSG-----SGQSPSRGRHGSGLGHSSSHGQHGSGS 2675
Query: 221 SAESS--PFGSPLLSRSVSLLKGFAQDSQAKVSQLRH------SVGRHGSLSADDSTPDA 272
SS P+ S L SV + SQ S G+HGS S ST D
Sbjct: 2676 GRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2735
Query: 273 SPGSRRRLTRRAPPEPGPESGQARGEH 299
S + + G G H
Sbjct: 2736 EGSSTGQSSSYGHRGSGSSQSSGYGRH 2762
Score = 32.3 bits (72), Expect = 0.83
Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 177 GSPGAGRRRAAAKANGGDG-GPREAGGALMSPGRY-FSGGESDTGSSAESSPFGSPLLSR 234
G G+G R++ + G G G + G S Y +S G ++GS ++S FG
Sbjct: 297 GRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG-QTSGFGQHESGS 355
Query: 235 SVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQ 294
S G+++ S S G+HGS S S+ S R+ + E
Sbjct: 356 GQS--SGYSKHGSG--SGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSS 411
Query: 295 ARGEHT 300
RG+H+
Sbjct: 412 GRGQHS 417
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/142 (23%), Positives = 46/142 (32%), Gaps = 10/142 (7%)
Query: 168 SEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPF 227
S G+ + G G+G R+++ G G G S GS + S
Sbjct: 1211 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 1270
Query: 228 GSPLLSRS--VSLLKGFAQDSQAKVSQLRH--------SVGRHGSLSADDSTPDASPGSR 277
P SRS S+ S + +H S G+HGS S ST D S
Sbjct: 1271 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1330
Query: 278 RRLTRRAPPEPGPESGQARGEH 299
+ + G G H
Sbjct: 1331 GQSSSYGHRGSGSSQSSGYGRH 1352
Score = 32.0 bits (71), Expect = 1.1
Identities = 32/141 (22%), Positives = 48/141 (34%), Gaps = 10/141 (7%)
Query: 168 SEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPF 227
S G+ ++ G G+G R+++ G G G S GS + S
Sbjct: 2151 SSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSS 2210
Query: 228 GSPLLSRS--VSLLKGFAQDSQAKVSQLRH--------SVGRHGSLSADDSTPDASPGSR 277
P SRS S+ S + +H S G+HGS S ST D S
Sbjct: 2211 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2270
Query: 278 RRLTRRAPPEPGPESGQARGE 298
+ + G + G+
Sbjct: 2271 GQSSSHGQHGSGSSQSSSYGQ 2291
Score = 31.2 bits (69), Expect = 1.8
Identities = 35/140 (25%), Positives = 46/140 (32%), Gaps = 8/140 (5%)
Query: 168 SEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGAL--MSPGRYFSGGESDTGSSAESS 225
S G + G G+G +++ G G S G S G+ +G+S SS
Sbjct: 744 SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSS 803
Query: 226 ----PFGSPLLSRSVSLLKGFAQDSQAKVSQLRH--SVGRHGSLSADDSTPDASPGSRRR 279
GS S G Q S H S GRHGS S S+ S +
Sbjct: 804 CGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQ 863
Query: 280 LTRRAPPEPGPESGQARGEH 299
+ E RG H
Sbjct: 864 SSSYGQHESASHHASGRGRH 883
Score = 31.2 bits (69), Expect = 1.8
Identities = 35/150 (23%), Positives = 51/150 (34%), Gaps = 9/150 (6%)
Query: 167 HSEHGALA----QVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSA 222
H +HG+ + G GA ++++ G G + +G G S G GS +
Sbjct: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
Query: 223 ESSP----FGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRR 278
SP GS S S G + S G+ S S S S G +
Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
Query: 279 RLTRRAPPEPGPESGQARGEHTVHVGPRGS 308
+R G G + G + G GS
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSS-RYGQHGS 2164
Score = 29.3 bits (64), Expect = 7.0
Identities = 31/137 (22%), Positives = 46/137 (33%), Gaps = 8/137 (5%)
Query: 167 HSEHGALA----QVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSA 222
H +HG+ + G GA ++++ G G + +G G S G GS +
Sbjct: 1546 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 1605
Query: 223 ESSP----FGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRR 278
SP GS S S G + S G+ S S S S G +
Sbjct: 1606 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 1665
Query: 279 RLTRRAPPEPGPESGQA 295
+R G G +
Sbjct: 1666 HGSRSGQSSRGERHGSS 1682
Score = 28.9 bits (63), Expect = 9.2
Identities = 33/142 (23%), Positives = 52/142 (36%), Gaps = 10/142 (7%)
Query: 169 EHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFG 228
+HG+ ++ S G+ +A++ + G G G G+ SG S + FG
Sbjct: 389 QHGSSSRQSS-SYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFG 447
Query: 229 SPLLSRSVSLLKGFAQDSQAKVSQLRHSVG--RHGSLSADDSTPDASPGSRRRLTRRAPP 286
S G++ S HS G +HGS S S G + +R
Sbjct: 448 RSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSS------GHGQHGSRSGQS 501
Query: 287 EPGPESGQARGEHTVHVGPRGS 308
G G + G + + G GS
Sbjct: 502 SRGERQGSSAGSSSSY-GQHGS 522
Score = 28.9 bits (63), Expect = 9.2
Identities = 32/122 (26%), Positives = 43/122 (35%), Gaps = 12/122 (9%)
Query: 178 SPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLSRSVS 237
SPG G+R + + + G G S GR+ SG S +SS FG S S
Sbjct: 890 SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSG-------SGQSSGFGHKSSSGQSS 942
Query: 238 LLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPESGQARG 297
G+ Q S S +HGS S S + S + G G
Sbjct: 943 ---GYTQHGSG--SGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHG 997
Query: 298 EH 299
+H
Sbjct: 998 QH 999
Score = 28.9 bits (63), Expect = 9.2
Identities = 30/135 (22%), Positives = 46/135 (34%), Gaps = 10/135 (7%)
Query: 174 AQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSPLLS 233
++ G G+G R+++ G G + G S GS + S P S
Sbjct: 1687 SRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYES 1746
Query: 234 RS--VSLLKGFAQDSQAKVSQLRH--------SVGRHGSLSADDSTPDASPGSRRRLTRR 283
RS S+ S + +H S G+HGS S ST D S + +
Sbjct: 1747 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 1806
Query: 284 APPEPGPESGQARGE 298
G + G+
Sbjct: 1807 GQHGSGSSQSSSYGQ 1821
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 42.4 bits (98), Expect = 8e-04
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 315 YEAGQARLRVHLLAAEGL----YDRLCDARSINCCVGLCLVPG--KLQKQRSTIVKNSRR 368
Y+ L +L A+GL ++ L D V L L+PG K K ++ +N+
Sbjct: 99 YDRASCTLHCSILRAKGLKPMDFNGLADPY-----VKLHLLPGACKANKLKTKTQRNTLN 153
Query: 369 PVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLP 419
PV+NED + G+ + LRI V ++ L + +GE +PL L P
Sbjct: 154 PVWNEDLTYSGITDDDITHKVLRIAVCDE-DKLSHNEFIGEIRVPLRRLKP 203
Score = 28.9 bits (63), Expect = 9.2
Identities = 35/143 (24%), Positives = 59/143 (41%), Gaps = 13/143 (9%)
Query: 242 FAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSR----RRLTRRAPPEPGPESGQARG 297
F + + + +L+ S +H ++ + P ASP S R ++ E GQ
Sbjct: 190 FIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLL 249
Query: 298 EHTVHVGPRGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPG--KL 355
E RG + L Y + + L V +L L + S + V L P K
Sbjct: 250 EE------RGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYS-DPYVKTYLRPDVDKK 302
Query: 356 QKQRSTIVKNSRRPVFNEDFFFD 378
K ++ + K + P FNE+FF++
Sbjct: 303 SKHKTCVKKKTLNPEFNEEFFYE 325
>gi|4503431 dysferlin isoform 8 [Homo sapiens]
Length = 2080
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 322 LRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
LRV +L AE ++ D C V K+R+ ++KNS PV+NE F +D G
Sbjct: 2 LRVFILYAENVHTPDTDISDAYCSAVFAGV-----KKRTKVIKNSVNPVWNEGFEWDLKG 56
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
+ L + VV ++ R+ LGE ++PL +L
Sbjct: 57 IPLDQGSELHV-VVKDHETMGRNRFLGEAKVPLREVL 92
>gi|195976764 dysferlin isoform 14 [Homo sapiens]
Length = 2118
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 322 LRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
LRV +L AE ++ D C V K+R+ ++KNS PV+NE F +D G
Sbjct: 2 LRVFILYAENVHTPDTDISDAYCSAVFAGV-----KKRTKVIKNSVNPVWNEGFEWDLKG 56
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
+ L + VV ++ R+ LGE ++PL +L
Sbjct: 57 IPLDQGSELHV-VVKDHETMGRNRFLGEAKVPLREVL 92
>gi|195976762 dysferlin isoform 13 [Homo sapiens]
Length = 2097
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 322 LRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
LRV +L AE ++ D C V K+R+ ++KNS PV+NE F +D G
Sbjct: 2 LRVFILYAENVHTPDTDISDAYCSAVFAGV-----KKRTKVIKNSVNPVWNEGFEWDLKG 56
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
+ L + VV ++ R+ LGE ++PL +L
Sbjct: 57 IPLDQGSELHV-VVKDHETMGRNRFLGEAKVPLREVL 92
>gi|195976760 dysferlin isoform 12 [Homo sapiens]
Length = 2111
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 322 LRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
LRV +L AE ++ D C V K+R+ ++KNS PV+NE F +D G
Sbjct: 2 LRVFILYAENVHTPDTDISDAYCSAVFAGV-----KKRTKVIKNSVNPVWNEGFEWDLKG 56
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
+ L + VV ++ R+ LGE ++PL +L
Sbjct: 57 IPLDQGSELHV-VVKDHETMGRNRFLGEAKVPLREVL 92
>gi|195976758 dysferlin isoform 11 [Homo sapiens]
Length = 2101
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 322 LRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
LRV +L AE ++ D C V K+R+ ++KNS PV+NE F +D G
Sbjct: 2 LRVFILYAENVHTPDTDISDAYCSAVFAGV-----KKRTKVIKNSVNPVWNEGFEWDLKG 56
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
+ L + VV ++ R+ LGE ++PL +L
Sbjct: 57 IPLDQGSELHV-VVKDHETMGRNRFLGEAKVPLREVL 92
>gi|195976756 dysferlin isoform 10 [Homo sapiens]
Length = 2087
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 322 LRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
LRV +L AE ++ D C V K+R+ ++KNS PV+NE F +D G
Sbjct: 2 LRVFILYAENVHTPDTDISDAYCSAVFAGV-----KKRTKVIKNSVNPVWNEGFEWDLKG 56
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
+ L + VV ++ R+ LGE ++PL +L
Sbjct: 57 IPLDQGSELHV-VVKDHETMGRNRFLGEAKVPLREVL 92
>gi|195976754 dysferlin isoform 9 [Homo sapiens]
Length = 2066
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 6/97 (6%)
Query: 322 LRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFFDGLG 381
LRV +L AE ++ D C V K+R+ ++KNS PV+NE F +D G
Sbjct: 2 LRVFILYAENVHTPDTDISDAYCSAVFAGV-----KKRTKVIKNSVNPVWNEGFEWDLKG 56
Query: 382 PASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLL 418
+ L + VV ++ R+ LGE ++PL +L
Sbjct: 57 IPLDQGSELHV-VVKDHETMGRNRFLGEAKVPLREVL 92
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/111 (22%), Positives = 56/111 (50%), Gaps = 1/111 (0%)
Query: 307 GSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNS 366
G++ EY + V++ A GL + + + + + ++P K K ++ +++ +
Sbjct: 155 GTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKT 214
Query: 367 RRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSL 417
P F+E F F G+ +++LAL +++ RD ++GE +PL+ +
Sbjct: 215 LDPAFDETFTFYGIPYTQIQELALHFTILS-FDRFSRDDIIGEVLIPLSGI 264
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 40.8 bits (94), Expect = 0.002
Identities = 27/113 (23%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Query: 307 GSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNS 366
GS+ +Y + L V + A GL + + + + ++P K + ++ +++ +
Sbjct: 159 GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKT 218
Query: 367 RRPVFNEDFFFDGLGPASVRKLALRIKVVNKGSSLKRDTLLGEKELPLTSLLP 419
PVF+E F F G+ + ++ L L V++ RD ++GE +PL + P
Sbjct: 219 LDPVFDETFTFYGIPYSQLQDLVLHFLVLS-FDRFSRDDVIGEVMVPLAGVDP 270
Score = 28.9 bits (63), Expect = 9.2
Identities = 20/75 (26%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 306 RGSVRLLAEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVPGK--LQKQRSTIV 363
RG +++ Y+ R+ V +L A L S N V + + G+ + K+++ +
Sbjct: 292 RGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVK 351
Query: 364 KNSRRPVFNEDFFFD 378
K + P+FNE F +D
Sbjct: 352 KCTLNPIFNESFIYD 366
>gi|12545408 RAS p21 protein activator 2 [Homo sapiens]
Length = 849
Score = 39.7 bits (91), Expect = 0.005
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 21/113 (18%)
Query: 321 RLRVHLLAAEGL---YDRLCDARSINCCVGLCLVPGKLQKQRSTIVKNSRRPVFNEDFFF 377
+L VH+ A GL + CD + VG P + ++++ + K + P FNE F+F
Sbjct: 172 QLVVHIKACHGLPLINGQSCDPYATVSLVG----PSRNDQKKTKVKKKTSNPQFNEIFYF 227
Query: 378 DGLGPAS-------------VRKLALRIKVVNKGSSLKRDTLLGEKELPLTSL 417
+ +S + KL +RI + N G +L +D LGE ++P+ L
Sbjct: 228 EVTRSSSYTRKSQFQVEEEDIEKLEIRIDLWNNG-NLVQDVFLGEIKVPVNVL 279
>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
Length = 689
Score = 39.3 bits (90), Expect = 0.007
Identities = 47/198 (23%), Positives = 74/198 (37%), Gaps = 21/198 (10%)
Query: 57 PSGPAEGEG-QAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVIQI- 114
PSG A G Q GP PR + +P + + A +H++ +
Sbjct: 479 PSGDAGAPGVQGYPGPP---------GPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVA 529
Query: 115 -ESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSYGFAMLAESPHTRRKESLFHSEHGAL 173
+ ++ L+E A A +A GA+ + P G+ + PH GA+
Sbjct: 530 LKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPG-KQGPHGHPGPRGVPGIVGAV 588
Query: 174 AQVGSPGAGRRRA-------AAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSP 226
Q+G+ G +R + + G GP G PG+ +G + D GS
Sbjct: 589 GQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGE 648
Query: 227 FGSPLLSRSVSLLKGFAQ 244
G P L V L GF +
Sbjct: 649 AGRPGLPGPVG-LPGFCE 665
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 39.3 bits (90), Expect = 0.007
Identities = 45/166 (27%), Positives = 70/166 (42%), Gaps = 28/166 (16%)
Query: 53 PPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHVI 112
PPK P+ P + P T E+ + P QTP + +P A E SLL+ +
Sbjct: 1693 PPKAPAPPPK--------PETPEKTTSEKPPEQTPETA-MPEPPAPEKPSLLRPVEKEKE 1743
Query: 113 Q--IESAEDWLSEEATDADPQAQGAMSLPS-------VPKAQTSYGFAMLAESPHTRRKE 163
+ + E L E + Q + SL + +PKA+ + + AE P +RK+
Sbjct: 1744 KEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPT---KVKAEPPPKKRKK 1800
Query: 164 SLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGR 209
L + A A G PG +++ + G P E A+ PGR
Sbjct: 1801 WLKEAGGNATAGGGPPG-----SSSDSESSPGAPSEDERAV--PGR 1839
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 38.9 bits (89), Expect = 0.009
Identities = 41/144 (28%), Positives = 51/144 (35%), Gaps = 19/144 (13%)
Query: 154 AESPHTRRKESLFHSEHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFS- 212
AE P +R E LFH + S G G A + R A PGR S
Sbjct: 58 AEEPGKKRHERLFHRQDALWISTSSAGTGGAEPPALSPAPASPARPVSPA---PGRRLSL 114
Query: 213 -----GGESDTGSSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADD 267
G G S + P G+P SR L + + GR G
Sbjct: 115 WAVPPGPPLSGGLSPDPKPGGAPTSSRRPLLSSPSWGGPEPE--------GRAGGGIPGS 166
Query: 268 STPDASPGSRRRLTRRAPPEPGPE 291
S+P GSRR + APP P P+
Sbjct: 167 SSPHPGTGSRR--LKVAPPPPAPK 188
>gi|61742808 hypothetical protein LOC283638 isoform 2 [Homo sapiens]
Length = 1484
Score = 38.9 bits (89), Expect = 0.009
Identities = 76/286 (26%), Positives = 103/286 (36%), Gaps = 56/286 (19%)
Query: 52 IPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHV 111
+PP LP+ P G + +GP T P P P+L E L A +
Sbjct: 452 VPPVLPA-PLTPHGTSPVGPPT---------PPPAPTDPQLTKARKQEEDDSLSDAGTYT 501
Query: 112 IQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSY---------------GFAM---L 153
I+ E A+D EEA Q G + P + +A ++ G A L
Sbjct: 502 IETE-AQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMAL 560
Query: 154 AESPHTRRKESLFHSEHGALAQVGSPGAGR---RRAAAKANGGDGGPREAG--------- 201
+ +R + +EH L GSPG + R A+ + D G E G
Sbjct: 561 LQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPE 620
Query: 202 GAL------MSPGRYFSGGESDTG--SSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQL 253
G+L P +S G SS S P L S S L G + +S
Sbjct: 621 GSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDA 680
Query: 254 RHSVGRHG---SLSADDS---TPDASPG-SRRRLTRRAPPEPGPES 292
S G G + DS +P P SR R + RAP EP P S
Sbjct: 681 SGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPAS 726
>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo
sapiens]
Length = 1554
Score = 38.9 bits (89), Expect = 0.009
Identities = 76/286 (26%), Positives = 103/286 (36%), Gaps = 56/286 (19%)
Query: 52 IPPKLPSGPAEGEGQAALGPSTSEQNLASAAPRQTPRSPRLPAKLAAESKSLLKAATRHV 111
+PP LP+ P G + +GP T P P P+L E L A +
Sbjct: 522 VPPVLPA-PLTPHGTSPVGPPT---------PPPAPTDPQLTKARKQEEDDSLSDAGTYT 571
Query: 112 IQIESAEDWLSEEATDADPQAQGAMSLPSVPKAQTSY---------------GFAM---L 153
I+ E A+D EEA Q G + P + +A ++ G A L
Sbjct: 572 IETE-AQDTEVEEARKMIDQVFGVLESPELSRASSATFRPVIRGDRDESDDGGVAQRMAL 630
Query: 154 AESPHTRRKESLFHSEHGALAQVGSPGAGR---RRAAAKANGGDGGPREAG--------- 201
+ +R + +EH L GSPG + R A+ + D G E G
Sbjct: 631 LQEFASRPLGAAPQAEHQGLPVPGSPGGQKWVSRWASLADSYSDPGLTEDGLGRRGGEPE 690
Query: 202 GAL------MSPGRYFSGGESDTG--SSAESSPFGSPLLSRSVSLLKGFAQDSQAKVSQL 253
G+L P +S G SS S P L S S L G + +S
Sbjct: 691 GSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDA 750
Query: 254 RHSVGRHG---SLSADDS---TPDASPG-SRRRLTRRAPPEPGPES 292
S G G + DS +P P SR R + RAP EP P S
Sbjct: 751 SGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPAS 796
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 38.5 bits (88), Expect = 0.012
Identities = 35/105 (33%), Positives = 46/105 (43%), Gaps = 2/105 (1%)
Query: 185 RAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPF-GSPLLSRSVSLLKGFA 243
RA +A G + G S R S G S + S++ SS GS SRS S + ++
Sbjct: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYS 777
Query: 244 QDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEP 288
+ S+ R S R S S S SPG RRR R+P P
Sbjct: 778 RSRSRSRSRSRSSRSRSRSQSRSRSK-SYSPGRRRRSRSRSPTPP 821
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 38.1 bits (87), Expect = 0.015
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 16/168 (9%)
Query: 257 VGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGPE-SGQARGEHTVHVGP---RGSVRLL 312
V R ++ P + P +R+++ P E SG ++ G +G+++
Sbjct: 552 VPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDEVSGSVMSVYSGDFGNLEVKGNIQFA 611
Query: 313 AEYEAGQARLRVHLLAAEGLYDRLCDARSINCCVGLCLVP--GKLQKQRSTIVKNSRRPV 370
EY L V + + L + + V L+P GK+ K+++ +VK + PV
Sbjct: 612 IEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPV 671
Query: 371 FNEDFFFDGLGPASVRKLALRIKVVNKG----SSLKRDTLLGEKELPL 414
+NE + + K L+ + +N + KR++ LGE EL L
Sbjct: 672 YNEILRY------KIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDL 713
Score = 29.3 bits (64), Expect = 7.0
Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 324 VHLLAAEGLYDRLCDARSINCCVGLCLVPGKLQK--QRSTIVKNSRRPVFNEDFFFDGLG 381
VH+ E L L +N V ++P +K Q++ V + P+FN +DG
Sbjct: 770 VHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFR 829
Query: 382 PASVRKLALRIKV 394
P + + + + V
Sbjct: 830 PEDLMEACVELTV 842
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 38.1 bits (87), Expect = 0.015
Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 31/137 (22%)
Query: 171 GALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGESDTGSSAESSPFGSP 230
G QVG PG G DG P G LM P R+ GG D GS P
Sbjct: 487 GPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRF--GGGGDAGSK-------GP 537
Query: 231 LLSRSVSLLKGFAQDSQAKVSQLRHSVGRHGSLSADDSTPDASPGSRRRLTRRAPPEPGP 290
++S AQ+SQA+ + + G P LT R P P
Sbjct: 538 MVS---------AQESQAQAILQQARLALRG------------PAGPMGLTGRPGPVGPP 576
Query: 291 ESGQARGEHTVHVGPRG 307
SG +GE VGP+G
Sbjct: 577 GSGGLKGE-PGDVGPQG 592
Score = 29.6 bits (65), Expect = 5.4
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 169 EHGALAQVGSPGAGRRRAAAKANGGDGGPREAGGALMSPGRYFSGGE----SDTGSSAES 224
E G + Q+G PG R + A G D GP+ G + +PG GE + G E
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGAD-GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299
Query: 225 SPFG 228
P G
Sbjct: 1300 GPPG 1303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,431,954
Number of Sequences: 37866
Number of extensions: 977505
Number of successful extensions: 5527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 309
Number of HSP's that attempted gapping in prelim test: 4897
Number of HSP's gapped (non-prelim): 892
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.