Guide to the Human Genome
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Search of human proteins with 208879470

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|208879470 eukaryotic translation elongation factor 1 epsilon
1 isoform 2 [Homo sapiens]
         (139 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|208879470 eukaryotic translation elongation factor 1 epsilon ...   276   5e-75
gi|4758862 eukaryotic translation elongation factor 1 epsilon 1 ...   255   9e-69
gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]             42   1e-04
gi|4503481 eukaryotic translation elongation factor 1 gamma [Hom...    34   0.034
gi|11125770 aminoacyl tRNA synthetase complex-interacting multif...    30   0.48 
gi|14043022 methionyl-tRNA synthetase [Homo sapiens]                   28   1.8  
gi|47174859 tripartite motif-containing 46 [Homo sapiens]              28   1.8  
gi|118722347 over-expressed breast tumor protein [Homo sapiens]        28   3.1  
gi|11136628 eukaryotic translation elongation factor 1 beta 2 [H...    28   3.1  
gi|4503477 eukaryotic translation elongation factor 1 beta 2 [Ho...    28   3.1  
gi|83376130 eukaryotic translation elongation factor 1 beta 2 [H...    28   3.1  
gi|4885409 high density lipoprotein binding protein [Homo sapiens]     27   4.1  
gi|42716280 high density lipoprotein binding protein [Homo sapiens]    27   4.1  
gi|169215618 PREDICTED: similar to Glutathione S-transferase the...    27   5.4  
gi|148886661 exportin 4 [Homo sapiens]                                 27   5.4  
gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens]                      27   7.0  
gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens]                      27   7.0  
gi|13540529 BCL2-like 14 isoform 2 [Homo sapiens]                      27   7.0  
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho...    27   7.0  
gi|154707916 glutathione S-transferase, C-terminal domain contai...    27   7.0  
gi|149588660 glutathione S-transferase, C-terminal domain contai...    27   7.0  
gi|224589077 hypothetical protein LOC285600 isoform 1 [Homo sapi...    26   9.1  

>gi|208879470 eukaryotic translation elongation factor 1 epsilon 1
           isoform 2 [Homo sapiens]
          Length = 139

 Score =  276 bits (705), Expect = 5e-75
 Identities = 139/139 (100%), Positives = 139/139 (100%)

Query: 1   MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60
           MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL
Sbjct: 1   MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60

Query: 61  LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120
           LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL
Sbjct: 61  LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120

Query: 121 YYGLHRFIIRKLRHTEVGN 139
           YYGLHRFIIRKLRHTEVGN
Sbjct: 121 YYGLHRFIIRKLRHTEVGN 139


>gi|4758862 eukaryotic translation elongation factor 1 epsilon 1
           isoform 1 [Homo sapiens]
          Length = 174

 Score =  255 bits (651), Expect = 9e-69
 Identities = 128/129 (99%), Positives = 129/129 (100%)

Query: 1   MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60
           MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL
Sbjct: 1   MAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYL 60

Query: 61  LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120
           LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL
Sbjct: 61  LGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILL 120

Query: 121 YYGLHRFII 129
           YYGLHRFI+
Sbjct: 121 YYGLHRFIV 129


>gi|62241042 glutamyl-prolyl tRNA synthetase [Homo sapiens]
          Length = 1512

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 3/90 (3%)

Query: 32  VLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDI 91
           +L  +     T + +I  +L + A    L GS   E   +  WLE+  T++   SS +  
Sbjct: 39  ILHVSENVIFTDVNSILRYLARVATTAGLYGSNLMEHTEIDHWLEFSATKL---SSCDSF 95

Query: 92  HTLLKDLNSYLEDKVYLTGYNFTLADILLY 121
            + + +LN  L  + YL G + +LAD+ ++
Sbjct: 96  TSTINELNHCLSLRTYLVGNSLSLADLCVW 125


>gi|4503481 eukaryotic translation elongation factor 1 gamma [Homo
           sapiens]
          Length = 437

 Score = 34.3 bits (77), Expect = 0.034
 Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 24/110 (21%)

Query: 29  QIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSS- 87
           ++P  + ++G  +     IA ++    + E L GST E  A V QW+ +  + +   +S 
Sbjct: 57  KVPAFEGDDGFCVFESNAIAYYV----SNEELRGSTPEAAAQVVQWVSFADSDIVPPAST 112

Query: 88  -------------------KNDIHTLLKDLNSYLEDKVYLTGYNFTLADI 118
                              K ++  +L  L++YL+ + +L G   TLADI
Sbjct: 113 WVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADI 162


>gi|11125770 aminoacyl tRNA synthetase complex-interacting
           multifunctional protein 2 [Homo sapiens]
          Length = 320

 Score = 30.4 bits (67), Expect = 0.48
 Identities = 15/57 (26%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 65  AEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLY 121
           A    ++  W++  + Q+   SSK     + + +NS L    +L G   T+AD++L+
Sbjct: 227 AVNATLIDSWVDIAIFQLKEGSSKEKA-AVFRSMNSALGKSPWLAGNELTVADVVLW 282


>gi|14043022 methionyl-tRNA synthetase [Homo sapiens]
          Length = 900

 Score = 28.5 bits (62), Expect = 1.8
 Identities = 26/115 (22%), Positives = 48/115 (41%), Gaps = 26/115 (22%)

Query: 29  QIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVD----- 83
           ++PVLQ ++G  L   + I  +        + L S  E+  +  QWLE+  T++      
Sbjct: 47  KVPVLQLDSGNYLFSTSAICRY--------FFLLSGWEQDDLTNQWLEWEATELQPALSA 98

Query: 84  -----------GHSSKNDIHTLLKDLNSYL--EDKVYLTGYNFTLADILLYYGLH 125
                      G      +   L  ++  L  ++  +L G   +LADI+L+  L+
Sbjct: 99  ALYYLVVQGKKGEDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADIVLWGALY 153


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score = 28.5 bits (62), Expect = 1.8
 Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 32  VLQTNNGPSLTGLTTIAAHLVKQANKE--YLLGSTAEEKAIVQQWLE-YRVTQVDGHSSK 88
           V +T++G  +T + +    L  +  K   Y+LG+    +  + +  E  R T+V G  +K
Sbjct: 251 VRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAK 310

Query: 89  NDIHTLLKDLNSYLEDK 105
            ++  L++ L + LE+K
Sbjct: 311 EEVSQLVRGLGAVLEEK 327


>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
          Length = 384

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%)

Query: 33  LQTNNGPSLTGLTTIAAHLVKQ-ANKEYLLGSTAEEKAIVQQWLEYRVTQVDG 84
           L TN  P+ TGL T+   L  Q  ++ Y L    EE+A +Q +   R  +  G
Sbjct: 56  LDTNQAPNWTGLQTLLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALG 108


>gi|11136628 eukaryotic translation elongation factor 1 beta 2 [Homo
           sapiens]
          Length = 225

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 12/27 (44%), Positives = 18/27 (66%)

Query: 95  LKDLNSYLEDKVYLTGYNFTLADILLY 121
           L+ LN YL DK Y+ GY  + AD+ ++
Sbjct: 12  LQVLNDYLADKSYIEGYVPSQADVAVF 38


>gi|4503477 eukaryotic translation elongation factor 1 beta 2 [Homo
           sapiens]
          Length = 225

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 12/27 (44%), Positives = 18/27 (66%)

Query: 95  LKDLNSYLEDKVYLTGYNFTLADILLY 121
           L+ LN YL DK Y+ GY  + AD+ ++
Sbjct: 12  LQVLNDYLADKSYIEGYVPSQADVAVF 38


>gi|83376130 eukaryotic translation elongation factor 1 beta 2 [Homo
           sapiens]
          Length = 225

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 12/27 (44%), Positives = 18/27 (66%)

Query: 95  LKDLNSYLEDKVYLTGYNFTLADILLY 121
           L+ LN YL DK Y+ GY  + AD+ ++
Sbjct: 12  LQVLNDYLADKSYIEGYVPSQADVAVF 38


>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
          Length = 1268

 Score = 27.3 bits (59), Expect = 4.1
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 10/92 (10%)

Query: 45  TTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLL-----KDLN 99
           TTIA   VK++  +Y++G        +Q+ LE     V+   S +   T++     + L 
Sbjct: 296 TTIAVE-VKKSQHKYVIGPKGNS---LQEILERTGVSVEIPPSDSISETVILRGEPEKLG 351

Query: 100 SYLEDKVYLTGYNFTLADILLYYGLHRFIIRK 131
             L + VY    +FT++ +     LHRFII K
Sbjct: 352 QALTE-VYAKANSFTVSSVAAPSWLHRFIIGK 382


>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
          Length = 1268

 Score = 27.3 bits (59), Expect = 4.1
 Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 10/92 (10%)

Query: 45  TTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLL-----KDLN 99
           TTIA   VK++  +Y++G        +Q+ LE     V+   S +   T++     + L 
Sbjct: 296 TTIAVE-VKKSQHKYVIGPKGNS---LQEILERTGVSVEIPPSDSISETVILRGEPEKLG 351

Query: 100 SYLEDKVYLTGYNFTLADILLYYGLHRFIIRK 131
             L + VY    +FT++ +     LHRFII K
Sbjct: 352 QALTE-VYAKANSFTVSSVAAPSWLHRFIIGK 382


>gi|169215618 PREDICTED: similar to Glutathione S-transferase
           theta-4 [Homo sapiens]
          Length = 176

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 9/55 (16%)

Query: 74  WLEYRVTQVDGH--SSKNDIHTLLKDLNS-------YLEDKVYLTGYNFTLADIL 119
           WL+  + ++ G   S++   H + +  NS       +L+DK+++TG   +LAD++
Sbjct: 50  WLKLLIPKITGEEVSAEKMEHAVEEVKNSLQLFEEKFLQDKMFITGNQISLADLV 104


>gi|148886661 exportin 4 [Homo sapiens]
          Length = 1151

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 59  YLLG--STAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLA 116
           YLL   +  E   I  + +EY +     HSS+ DI+T L+ L S  E    + GYN T +
Sbjct: 548 YLLADDTQGETPLIPPEIMEYSIK----HSSEVDINTTLQILGSPGEKASSIPGYNRTDS 603

Query: 117 DILLYYGLHR 126
            I L   + R
Sbjct: 604 VIRLLSAILR 613


>gi|21040330 BCL2-like 14 isoform 1 [Homo sapiens]
          Length = 327

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 21/84 (25%), Positives = 34/84 (40%)

Query: 5   AELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGST 64
           A   ++EK    S   K SAQG+R +    +++      L+ +   L  +A    ++   
Sbjct: 95  AFFGVVEKEDSQSTPAKVSAQGQRTLEYQDSHSQQWSRCLSNVEQCLEHEAVDPKVISIA 154

Query: 65  AEEKAIVQQWLEYRVTQVDGHSSK 88
                IV  W   + TQ  G  SK
Sbjct: 155 NRVAEIVYSWPPPQATQAGGFKSK 178


>gi|21040328 BCL2-like 14 isoform 1 [Homo sapiens]
          Length = 327

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 21/84 (25%), Positives = 34/84 (40%)

Query: 5   AELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGST 64
           A   ++EK    S   K SAQG+R +    +++      L+ +   L  +A    ++   
Sbjct: 95  AFFGVVEKEDSQSTPAKVSAQGQRTLEYQDSHSQQWSRCLSNVEQCLEHEAVDPKVISIA 154

Query: 65  AEEKAIVQQWLEYRVTQVDGHSSK 88
                IV  W   + TQ  G  SK
Sbjct: 155 NRVAEIVYSWPPPQATQAGGFKSK 178


>gi|13540529 BCL2-like 14 isoform 2 [Homo sapiens]
          Length = 252

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 21/84 (25%), Positives = 34/84 (40%)

Query: 5   AELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGST 64
           A   ++EK    S   K SAQG+R +    +++      L+ +   L  +A    ++   
Sbjct: 95  AFFGVVEKEDSQSTPAKVSAQGQRTLEYQDSHSQQWSRCLSNVEQCLEHEAVDPKVISIA 154

Query: 65  AEEKAIVQQWLEYRVTQVDGHSSK 88
                IV  W   + TQ  G  SK
Sbjct: 155 NRVAEIVYSWPPPQATQAGGFKSK 178


>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
           sapiens]
          Length = 864

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 6/71 (8%)

Query: 33  LQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIH 92
           L++ N   L    T   HL+  A   Y L  + +EKAI         T++D      D+ 
Sbjct: 746 LESFNEDFLKRNATSLQHLLSGAKMMYFLDKSRQEKAIA------IATRLDETIKDKDVK 799

Query: 93  TLLKDLNSYLE 103
           TL+K   + L+
Sbjct: 800 TLIKVSEALLD 810


>gi|154707916 glutathione S-transferase, C-terminal domain
           containing isoform 2 [Homo sapiens]
          Length = 546

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 11/26 (42%), Positives = 17/26 (65%)

Query: 104 DKVYLTGYNFTLADILLYYGLHRFII 129
           + V+  G  FTLADI+L   +H F++
Sbjct: 187 EHVFAEGLYFTLADIVLLPCIHHFLV 212


>gi|149588660 glutathione S-transferase, C-terminal domain
           containing isoform 1 [Homo sapiens]
          Length = 633

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 11/26 (42%), Positives = 17/26 (65%)

Query: 104 DKVYLTGYNFTLADILLYYGLHRFII 129
           + V+  G  FTLADI+L   +H F++
Sbjct: 274 EHVFAEGLYFTLADIVLLPCIHHFLV 299


>gi|224589077 hypothetical protein LOC285600 isoform 1 [Homo sapiens]
          Length = 1275

 Score = 26.2 bits (56), Expect = 9.1
 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 8/120 (6%)

Query: 10   LEKSLGLSKGNKYSAQGERQIP--VLQTNNGPSLTGLTTIAAHLVKQANKEYLLG----- 62
            +EKS  L +G+      E++I   VL   + P          H++ Q N+EYL       
Sbjct: 1104 IEKSTALQEGDVALELTEQKINTMVLDLCHKPGGREYLRQIYHIM-QLNEEYLKEQLFSM 1162

Query: 63   STAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYY 122
            +++EEK +  + L+  +  ++   S  +   + K  +  + D+V +T +N+  A +L  Y
Sbjct: 1163 NSSEEKPLPIRPLKTTLRSIEDQPSAFNPFHVYKAFSENMLDQVSITKWNWNWAKLLPNY 1222


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,722,448
Number of Sequences: 37866
Number of extensions: 180402
Number of successful extensions: 411
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 397
Number of HSP's gapped (non-prelim): 22
length of query: 139
length of database: 18,247,518
effective HSP length: 92
effective length of query: 47
effective length of database: 14,763,846
effective search space: 693900762
effective search space used: 693900762
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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