Search of human proteins with 205277465

Search of human proteins with 205277465

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|205277465 transketolase isoform 2 [Homo sapiens]
         (540 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|205277465 transketolase isoform 2 [Homo sapiens]                  1071   0.0  
gi|205277463 transketolase isoform 1 [Homo sapiens]                   967   0.0  
gi|4507521 transketolase isoform 1 [Homo sapiens]                     967   0.0  
gi|225637459 transketolase-like 1 isoform a [Homo sapiens]            665   0.0  
gi|133778974 transketolase-like 2 [Homo sapiens]                      663   0.0  
gi|225637461 transketolase-like 1 isoform b [Homo sapiens]            646   0.0  
gi|225637463 transketolase-like 1 isoform c [Homo sapiens]            627   e-180
gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]    51   2e-06
gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens]       34   0.30 
gi|11386135 branched chain keto acid dehydrogenase E1, alpha pol...    33   0.66 
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]        31   2.5  
gi|217416354 sphingosine kinase type 1-interacting protein isofo...    31   3.3  
gi|217416352 sphingosine kinase type 1-interacting protein isofo...    31   3.3  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    30   4.3  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     29   9.6  
gi|14780904 kelch-like 1 protein [Homo sapiens]                        29   9.6  

>gi|205277465 transketolase isoform 2 [Homo sapiens]
          Length = 540

 Score = 1071 bits (2771), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFD 60
           MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFD
Sbjct: 1   MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFD 60

Query: 61  KASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQ 120
           KASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQ
Sbjct: 61  KASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQ 120

Query: 121 KRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLP 180
           KRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLP
Sbjct: 121 KRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLP 180

Query: 181 KNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQ 240
           KNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQ
Sbjct: 181 KNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQ 240

Query: 241 ALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTV 300
           ALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTV
Sbjct: 241 ALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTV 300

Query: 301 PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTS 360
           PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTS
Sbjct: 301 PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTS 360

Query: 361 TVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQV 420
           TVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQV
Sbjct: 361 TVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQV 420

Query: 421 TVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHY 480
           TVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHY
Sbjct: 421 TVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHY 480

Query: 481 YEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA 540
           YEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
Sbjct: 481 YEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA 540


>gi|205277463 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  967 bits (2499), Expect = 0.0
 Identities = 492/512 (96%), Positives = 495/512 (96%), Gaps = 9/512 (1%)

Query: 29  ATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 88
           AT + G G   +C  A         +TGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS
Sbjct: 121 ATGSLGQGLGAACGMA---------YTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 171

Query: 89  IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA 148
           IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA
Sbjct: 172 IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA 231

Query: 149 KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQE 208
           KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQE
Sbjct: 232 KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQE 291

Query: 209 DAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIF 268
           DAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIF
Sbjct: 292 DAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIF 351

Query: 269 KKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNIN 328
           KKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNIN
Sbjct: 352 KKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNIN 411

Query: 329 LCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIR 388
           LCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIR
Sbjct: 412 LCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIR 471

Query: 389 TSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRV 448
           TSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRV
Sbjct: 472 TSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRV 531

Query: 449 LDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNR 508
           LDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNR
Sbjct: 532 LDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNR 591

Query: 509 VPRSGKPAELLKMFGIDRDAIAQAVRGLITKA 540
           VPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
Sbjct: 592 VPRSGKPAELLKMFGIDRDAIAQAVRGLITKA 623



 Score =  115 bits (289), Expect = 8e-26
 Identities = 56/58 (96%), Positives = 57/58 (98%)

Query: 1  MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKY 58
          MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHT +Y
Sbjct: 1  MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRY 58


>gi|4507521 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  967 bits (2499), Expect = 0.0
 Identities = 492/512 (96%), Positives = 495/512 (96%), Gaps = 9/512 (1%)

Query: 29  ATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 88
           AT + G G   +C  A         +TGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS
Sbjct: 121 ATGSLGQGLGAACGMA---------YTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 171

Query: 89  IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA 148
           IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA
Sbjct: 172 IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA 231

Query: 149 KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQE 208
           KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQE
Sbjct: 232 KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQE 291

Query: 209 DAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIF 268
           DAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIF
Sbjct: 292 DAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIF 351

Query: 269 KKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNIN 328
           KKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNIN
Sbjct: 352 KKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNIN 411

Query: 329 LCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIR 388
           LCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIR
Sbjct: 412 LCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIR 471

Query: 389 TSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRV 448
           TSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRV
Sbjct: 472 TSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRV 531

Query: 449 LDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNR 508
           LDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNR
Sbjct: 532 LDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNR 591

Query: 509 VPRSGKPAELLKMFGIDRDAIAQAVRGLITKA 540
           VPRSGKPAELLKMFGIDRDAIAQAVRGLITKA
Sbjct: 592 VPRSGKPAELLKMFGIDRDAIAQAVRGLITKA 623



 Score =  115 bits (289), Expect = 8e-26
 Identities = 56/58 (96%), Positives = 57/58 (98%)

Query: 1  MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKY 58
          MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHT +Y
Sbjct: 1  MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRY 58


>gi|225637459 transketolase-like 1 isoform a [Homo sapiens]
          Length = 596

 Score =  665 bits (1715), Expect = 0.0
 Identities = 336/580 (57%), Positives = 425/580 (73%), Gaps = 48/580 (8%)

Query: 6   KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFH----------- 54
           +PD+  LQ L+D A+RLRI SI+AT +  SGHPTSC S++EIM+VLFF+           
Sbjct: 15  RPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDPEN 74

Query: 55  ----------------------------------TGKYFDKASYRVYCLLGDGELSEGSV 80
                                             TGKYFD+ASYRV+CL+ DGE SEGSV
Sbjct: 75  PDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSV 134

Query: 81  WEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEE 140
           WEAMAFAS Y LDNLVAI D+NRLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE 
Sbjct: 135 WEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEA 194

Query: 141 LCKAFGQA---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQS 197
           LC+ F QA   KH+PTA++AKTFKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+
Sbjct: 195 LCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQT 254

Query: 198 KKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDG 257
            + +   PP ED+P V+I ++RM S P Y+VGDKIATRKA G ALAKLG+A++R++ LDG
Sbjct: 255 SRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDG 314

Query: 258 DTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQI 317
           DT+ STFSEIF KE+P+RFIEC++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD I
Sbjct: 315 DTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI 374

Query: 318 RMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVEL 377
           R+  ++ESNIN+ GSHCGVS+G+DG SQMALED+AMFR++P  T+FYP+D V+TE AV L
Sbjct: 375 RIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVAL 434

Query: 378 AANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAE 437
           AAN KG+CFIRT+RPE  +IY   E F++GQAKV+     D+VTVIGAG+T++EALAAA+
Sbjct: 435 AANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAAD 494

Query: 438 LLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEP 497
            L K+ I IRV+D FTIKPLD   I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P
Sbjct: 495 ELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 554

Query: 498 GITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 537
            I V  LAV+ VP+SGK  ELL M+GI    I  AV+ ++
Sbjct: 555 DIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 594


>gi|133778974 transketolase-like 2 [Homo sapiens]
          Length = 626

 Score =  663 bits (1710), Expect = 0.0
 Identities = 331/508 (65%), Positives = 398/508 (78%), Gaps = 12/508 (2%)

Query: 29  ATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFAS 88
           AT + G G  T+C  A         +TGKY DKASYRV+CL+GDGE SEGSVWEA AFAS
Sbjct: 122 ATGSLGQGLGTACGMA---------YTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFAS 172

Query: 89  IYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA 148
            Y LDNLVA+ D+NRLGQS PAPL+H  DIYQ  CEAFGW+  +VDGH VE LC+AF QA
Sbjct: 173 HYNLDNLVAVFDVNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQA 232

Query: 149 ---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATP 205
              K++PTAI+AKTFKGRGI  +ED E+WHGKP+PK  A+ I++ I SQIQ+ + ++   
Sbjct: 233 SQVKNKPTAIVAKTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKS 292

Query: 206 PQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFS 265
           P ED+P + I +I+M S P+YKVGDKIAT+K YG ALAKLG A++R+I L GDT NSTFS
Sbjct: 293 PVEDSPQISITDIKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFS 352

Query: 266 EIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISES 325
           EIF+KEHP+RFIEC IAEQNMVS+A+GCATR RT+ F   FAAFFTRAFDQ+RM AIS++
Sbjct: 353 EIFRKEHPERFIECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQA 412

Query: 326 NINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGIC 385
           NINL GSHCGVS GEDG SQMALEDLAMFRS+P  TVFYPSD ++TE A+ LAANTKG+C
Sbjct: 413 NINLIGSHCGVSTGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMC 472

Query: 386 FIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKIN 445
           FIRTS+PE A+IY   E+F++GQAKVV    +D+VTVIGAGVTLHEAL AA+ L ++ I+
Sbjct: 473 FIRTSQPETAVIYTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGIS 532

Query: 446 IRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLA 505
           +RV+DPFTIKPLD   I+ SA+AT GR++TVEDHY EGGIGEAV +AV  EP I V  LA
Sbjct: 533 VRVIDPFTIKPLDAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLA 592

Query: 506 VNRVPRSGKPAELLKMFGIDRDAIAQAV 533
           V+ VP+ GK +ELL MFGI    I  AV
Sbjct: 593 VSGVPQRGKTSELLDMFGISTRHIIAAV 620



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 37/53 (69%), Positives = 45/53 (84%)

Query: 6  KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTGKY 58
          KPD + +Q L+DTANRLRI SI+AT A+GSG  TSCCSAAE+++VLFFHT KY
Sbjct: 7  KPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKY 59


>gi|225637461 transketolase-like 1 isoform b [Homo sapiens]
          Length = 590

 Score =  646 bits (1666), Expect = 0.0
 Identities = 331/580 (57%), Positives = 420/580 (72%), Gaps = 54/580 (9%)

Query: 6   KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFH----------- 54
           +PD+  LQ L+D A+RLRI SI+AT +  SG      S++EIM+VLFF+           
Sbjct: 15  RPDRGTLQVLQDMASRLRIHSIRATCSTSSG------SSSEIMSVLFFYIMRYKQSDPEN 68

Query: 55  ----------------------------------TGKYFDKASYRVYCLLGDGELSEGSV 80
                                             TGKYFD+ASYRV+CL+ DGE SEGSV
Sbjct: 69  PDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSV 128

Query: 81  WEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEE 140
           WEAMAFAS Y LDNLVAI D+NRLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE 
Sbjct: 129 WEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEA 188

Query: 141 LCKAFGQA---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQS 197
           LC+ F QA   KH+PTA++AKTFKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+
Sbjct: 189 LCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQT 248

Query: 198 KKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDG 257
            + +   PP ED+P V+I ++RM S P Y+VGDKIATRKA G ALAKLG+A++R++ LDG
Sbjct: 249 SRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDG 308

Query: 258 DTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQI 317
           DT+ STFSEIF KE+P+RFIEC++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD I
Sbjct: 309 DTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI 368

Query: 318 RMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVEL 377
           R+  ++ESNIN+ GSHCGVS+G+DG SQMALED+AMFR++P  T+FYP+D V+TE AV L
Sbjct: 369 RIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVAL 428

Query: 378 AANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAE 437
           AAN KG+CFIRT+RPE  +IY   E F++GQAKV+     D+VTVIGAG+T++EALAAA+
Sbjct: 429 AANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAAD 488

Query: 438 LLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEP 497
            L K+ I IRV+D FTIKPLD   I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P
Sbjct: 489 ELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 548

Query: 498 GITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 537
            I V  LAV+ VP+SGK  ELL M+GI    I  AV+ ++
Sbjct: 549 DIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 588


>gi|225637463 transketolase-like 1 isoform c [Homo sapiens]
          Length = 540

 Score =  627 bits (1617), Expect = e-180
 Identities = 313/519 (60%), Positives = 396/519 (76%), Gaps = 13/519 (2%)

Query: 23  RISSIQATTA-AGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYCLLGDGELSEGSVW 81
           R+S +   T   G G   +C  A         +TGKYFD+ASYRV+CL+ DGE SEGSVW
Sbjct: 29  RLSFVDVATGWLGQGLGVACGMA---------YTGKYFDRASYRVFCLMSDGESSEGSVW 79

Query: 82  EAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEEL 141
           EAMAFAS Y LDNLVAI D+NRLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE L
Sbjct: 80  EAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEAL 139

Query: 142 CKAFGQA---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSK 198
           C+ F QA   KH+PTA++AKTFKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+ 
Sbjct: 140 CQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTS 199

Query: 199 KKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGD 258
           + +   PP ED+P V+I ++RM S P Y+VGDKIATRKA G ALAKLG+A++R++ LDGD
Sbjct: 200 RNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGD 259

Query: 259 TKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIR 318
           T+ STFSEIF KE+P+RFIEC++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD IR
Sbjct: 260 TRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIR 319

Query: 319 MAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELA 378
           +  ++ESNIN+ GSHCGVS+G+DG SQMALED+AMFR++P  T+FYP+D V+TE AV LA
Sbjct: 320 IGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALA 379

Query: 379 ANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAEL 438
           AN KG+CFIRT+RPE  +IY   E F++GQAKV+     D+VTVIGAG+T++EALAAA+ 
Sbjct: 380 ANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADE 439

Query: 439 LKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPG 498
           L K+ I IRV+D FTIKPLD   I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P 
Sbjct: 440 LSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPD 499

Query: 499 ITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 537
           I V  LAV+ VP+SGK  ELL M+GI    I  AV+ ++
Sbjct: 500 IQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 538


>gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]
          Length = 359

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 64/277 (23%), Positives = 110/277 (39%), Gaps = 34/277 (12%)

Query: 267 IFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFT-RAFDQIRMAAISES 325
           ++KK    R I+  I+E     IAVG A      P C      F+ +A DQ+  +A    
Sbjct: 73  LWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLR-PICEFMTFNFSMQAIDQVINSAAK-- 129

Query: 326 NINLCGSHCGVSIGEDGPS--------QMALEDLAMFRSVPTSTVFYPSDGVATEKAVEL 377
              + G    V I   GP+        Q +    A +   P   V  P +    +  ++ 
Sbjct: 130 TYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKS 189

Query: 378 AANTKGICFIRTSRP----ENAIIYN---------NNEDFQVGQAKVVLKSKDDQVTVIG 424
           A        IR + P    EN ++Y           ++DF +   K  ++ +   +TV+ 
Sbjct: 190 A--------IRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVS 241

Query: 425 AGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGG 484
               +   L AA +L KE +   V++  TI+P+D + I  S   T   ++TVE  + + G
Sbjct: 242 HSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKT-NHLVTVEGGWPQFG 300

Query: 485 IGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKM 521
           +G  + + ++  P          RV  +  P    K+
Sbjct: 301 VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKI 337


>gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens]
          Length = 469

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)

Query: 158 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 217
           K F G GI+ +  KE + G P  K M  ++ + +Y        +      ++ PS  +++
Sbjct: 169 KVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSH 228

Query: 218 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALD 256
           +  P  P  K+ D  A        +A L H    +IALD
Sbjct: 229 VLNPQ-PGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266


>gi|11386135 branched chain keto acid dehydrogenase E1, alpha
           polypeptide [Homo sapiens]
          Length = 445

 Score = 33.1 bits (74), Expect = 0.66
 Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 7/102 (6%)

Query: 66  VYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEA 125
           V C  G+G  SEG       FA+  +   ++     N    S P   Q++ D    R   
Sbjct: 232 VICYFGEGAASEGDAHAGFNFAATLECP-IIFFCRNNGYAISTPTSEQYRGDGIAARGPG 290

Query: 126 FGWHAIIVDGHSVEELCKAFGQAK------HQPTAIIAKTFK 161
           +G  +I VDG+ V  +  A  +A+      +QP  I A T++
Sbjct: 291 YGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYR 332


>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
          Length = 5183

 Score = 31.2 bits (69), Expect = 2.5
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)

Query: 286  MVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGS 332
            +V I +  A  N +  FC+    FFT+ F Q+   + + S ++LCGS
Sbjct: 1407 LVQIMMATANENLSAKFCNRVLKFFTKLF-QLTEKSPNPSLLHLCGS 1452


>gi|217416354 sphingosine kinase type 1-interacting protein isoform
           1 [Homo sapiens]
          Length = 1700

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 6/67 (8%)

Query: 169 EDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKV 228
           +D E   GK    N+AE ++Q+ + ++   +  L   PQE A SV + +  +PS   Y  
Sbjct: 382 QDGEVTTGK-YATNLAESVLQDAFIRLSQSQSTL---PQESAVSVSVGSSLLPS--CYST 435

Query: 229 GDKIATR 235
            D + +R
Sbjct: 436 KDTVVSR 442


>gi|217416352 sphingosine kinase type 1-interacting protein isoform
           2 [Homo sapiens]
          Length = 1671

 Score = 30.8 bits (68), Expect = 3.3
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 6/67 (8%)

Query: 169 EDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKV 228
           +D E   GK    N+AE ++Q+ + ++   +  L   PQE A SV + +  +PS   Y  
Sbjct: 382 QDGEVTTGK-YATNLAESVLQDAFIRLSQSQSTL---PQESAVSVSVGSSLLPS--CYST 435

Query: 229 GDKIATR 235
            D + +R
Sbjct: 436 KDTVVSR 442


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 30.4 bits (67), Expect = 4.3
 Identities = 26/106 (24%), Positives = 44/106 (41%), Gaps = 19/106 (17%)

Query: 164 GITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSL 223
           G+  + D+E W  K   K   E+++QE  S  + +K      P++     D   I     
Sbjct: 530 GVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQK------PRQLKDKADFCIIHYAGK 583

Query: 224 PSYK-----------VGDKIAT--RKAYGQALAKLGHASDRIIALD 256
             YK           + D +AT   ++  + +A+L    DRI+ LD
Sbjct: 584 VDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIVGLD 629


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 19/115 (16%)

Query: 155 IIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVD 214
           +I K     GI  + D+E W  K   K+  E+++QE  +  + +K      P++     D
Sbjct: 514 LIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQK------PKQLKDKAD 567

Query: 215 IANIRMPSLPSYK-----------VGDKIAT--RKAYGQALAKLGHASDRIIALD 256
              I       YK           + D IAT   ++  + +++L    DRII LD
Sbjct: 568 FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLD 622


>gi|14780904 kelch-like 1 protein [Homo sapiens]
          Length = 748

 Score = 29.3 bits (64), Expect = 9.6
 Identities = 23/104 (22%), Positives = 39/104 (37%), Gaps = 10/104 (9%)

Query: 233 ATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVG 292
           AT +  G  L+  GH+      LD  +    +  +   E   R +E Y+ +Q +  + + 
Sbjct: 158 ATGEGCGHRLSSTGHSMTPQSDLDSSSSEEFYQAVHHAEQTFRKMESYLKQQQLCDVIL- 216

Query: 293 CATRNRTVP--------FCSTFAAFFTRAFDQIRMAAISESNIN 328
               NR +P            FAA FT    + +   I    I+
Sbjct: 217 -IVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAKQEEIKMEGID 259


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,099,703
Number of Sequences: 37866
Number of extensions: 811636
Number of successful extensions: 1850
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1830
Number of HSP's gapped (non-prelim): 23
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.