Search of human proteins with 20270333

Search of human proteins with 20270333

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20270333 PIH1 domain containing 2 isoform 1 [Homo sapiens]
         (315 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20270333 PIH1 domain containing 2 isoform 1 [Homo sapiens]         625   e-179
gi|130499472 PIH1 domain containing 2 isoform 2 [Homo sapiens]        541   e-154
gi|8923598 NOP17 [Homo sapiens]                                        51   1e-06
gi|145580586 kintoun isoform 2 [Homo sapiens]                          49   6e-06
gi|145580588 kintoun isoform 1 [Homo sapiens]                          49   6e-06
gi|4759082 serum deprivation response protein [Homo sapiens]           34   0.19 
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               31   1.3  
gi|33859793 hypothetical protein LOC139212 [Homo sapiens]              31   1.6  
gi|38261962 activating transcription factor 7 interacting protei...    30   2.8  
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...    30   2.8  
gi|40538794 coiled-coil domain containing 21 [Homo sapiens]            30   3.6  
gi|4502175 apical protein of Xenopus-like [Homo sapiens]               29   4.8  

>gi|20270333 PIH1 domain containing 2 isoform 1 [Homo sapiens]
          Length = 315

 Score =  625 bits (1611), Expect = e-179
 Identities = 315/315 (100%), Positives = 315/315 (100%)

Query: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60
           METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK
Sbjct: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60

Query: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120
           PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK
Sbjct: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120

Query: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180
           DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM
Sbjct: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180

Query: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240
           RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV
Sbjct: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240

Query: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSEDDLLIEVSEKYRLHLNLPKLIDTEMTTAK 300
           HDHSEKPLKIELKVELPGINSVSLCDLSVSEDDLLIEVSEKYRLHLNLPKLIDTEMTTAK
Sbjct: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSEDDLLIEVSEKYRLHLNLPKLIDTEMTTAK 300

Query: 301 FIKEKSTLIITMPLV 315
           FIKEKSTLIITMPLV
Sbjct: 301 FIKEKSTLIITMPLV 315


>gi|130499472 PIH1 domain containing 2 isoform 2 [Homo sapiens]
          Length = 288

 Score =  541 bits (1395), Expect = e-154
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60
           METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK
Sbjct: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPEPQLCLQTRILK 60

Query: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120
           PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK
Sbjct: 61  PKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVIDVAYNPDVLHAAEK 120

Query: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180
           DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM
Sbjct: 121 DQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSIDLREKM 180

Query: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240
           RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV
Sbjct: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240

Query: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSE 271
           HDHSEKPLKIELKVELPGINSVSLCDLSVSE
Sbjct: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSE 271


>gi|8923598 NOP17 [Homo sapiens]
          Length = 290

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 65/316 (20%), Positives = 122/316 (38%), Gaps = 73/316 (23%)

Query: 25  SDPEGYEKFIQQQLKEGKQLCAA--------PEPQLCLQTRILKPKEKILFINLCQWTRI 76
           +D   +E+ + Q  KE +Q            P+P  C++T   + K   +FIN+C    I
Sbjct: 19  ADSARFEELLLQASKELQQAQTTRPESTQIQPQPGFCIKTNSSEGK---VFINICHSPSI 75

Query: 77  PAPQSTTHP--------------VPLTVGKPEDTTEIS-DAYTVIDVAYNPDVLHAAEKD 121
           P P   T                +P+++G+P    +      T  DVA N D     +  
Sbjct: 76  PPPADVTEEELLQMLEEDQAGFRIPMSLGEPHAELDAKGQGCTAYDVAVNSDFYRRMQNS 135

Query: 122 QVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFR-IKGSIQRMKQNLMGIQTDSIDLREKM 180
              +  +I +A + +E+K+   L+  + + K R   GSI   +QN+           E+ 
Sbjct: 136 DFLRELVITIAREGLEDKYNLQLNPEWRMMKNRPFMGSIS--QQNIRS---------EQR 184

Query: 181 RRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPAYELKIV 240
            R   LG + +      +  P+                              P   L + 
Sbjct: 185 PRIQELGDLYTPAPGRAESGPE-----------------------------KPHLNLWL- 214

Query: 241 HDHSEKPLKIELKVELPGINSVSLCDLSVSEDDLLIEVSEK-YRLHLNLPKLIDTEMTTA 299
               E P  +  +V+LP ++      L + E+ L++   ++ Y L   +P  I++  + A
Sbjct: 215 ----EAPDLLLAEVDLPKLDGALGLSLEIGENRLVMGGPQQLYHLDAYIPLQINSHESKA 270

Query: 300 KFIKEKSTLIITMPLV 315
            F +++  L++ MPL+
Sbjct: 271 AFHRKRKQLMVAMPLL 286


>gi|145580586 kintoun isoform 2 [Homo sapiens]
          Length = 789

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 68/290 (23%), Positives = 116/290 (40%), Gaps = 34/290 (11%)

Query: 48  PEPQLCLQTRILKPKEKILFINLCQWTRIPAPQST---------------THPVPLTVGK 92
           PEP   L+T +   +    F+N+C    + AP S                + P  L  G+
Sbjct: 72  PEPGHVLRTSLDGARR--CFVNVCSNALVGAPSSRPGSGGDRGAAPGSHWSLPYSLAPGR 129

Query: 93  PEDTTEISDAYTVIDVAYNPDVLHAAEKDQVKKNQLIQMAMKCIEEKFQFTLSHSYHIT- 151
            E     S  Y V DV ++PD L  A + +  +  L   A++ +E++F   L      T 
Sbjct: 130 -EYAGRSSSRYMVYDVVFHPDALALARRHEGFRQMLDATALEAVEKQFGVKLDRRNAKTL 188

Query: 152 KFRIKGSIQR--MKQNLMGIQTDSIDLREKMRRELTLGQIRSSTMSNPDHFPQLLLPKDQ 209
           K + KG+ +   ++  L G+     D   K       G +       P  +P    P+  
Sbjct: 189 KAKYKGTPEAAVLRTPLPGVIPARPDGEPK-------GPLPD--FPYPYQYPAAPGPRAP 239

Query: 210 VSGKAVCL---IEEISSTEIQVEMKMPAYELKIVHDHSEKPLKIELKVELPGINSVSLCD 266
              +A       E   S   +  + +  Y        S  P ++ + +ELP + S     
Sbjct: 240 SPPEAALQPAPTEPRYSVVQRHHVDLQDYRCSRDSAPSPVPHELVITIELPLLRSAEQAA 299

Query: 267 LSVSEDDLLIEVSEK-YRLHLNLPKLIDTEMTTAKFIKEKSTLIITMPLV 315
           L V+   L ++  +  YRL L+LP  +D     A+F K +  L++T+P+V
Sbjct: 300 LEVTRKLLCLDSRKPDYRLRLSLPYPVDDGRGKAQFNKARRQLVVTLPVV 349


>gi|145580588 kintoun isoform 1 [Homo sapiens]
          Length = 837

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 68/290 (23%), Positives = 116/290 (40%), Gaps = 34/290 (11%)

Query: 48  PEPQLCLQTRILKPKEKILFINLCQWTRIPAPQST---------------THPVPLTVGK 92
           PEP   L+T +   +    F+N+C    + AP S                + P  L  G+
Sbjct: 72  PEPGHVLRTSLDGARR--CFVNVCSNALVGAPSSRPGSGGDRGAAPGSHWSLPYSLAPGR 129

Query: 93  PEDTTEISDAYTVIDVAYNPDVLHAAEKDQVKKNQLIQMAMKCIEEKFQFTLSHSYHIT- 151
            E     S  Y V DV ++PD L  A + +  +  L   A++ +E++F   L      T 
Sbjct: 130 -EYAGRSSSRYMVYDVVFHPDALALARRHEGFRQMLDATALEAVEKQFGVKLDRRNAKTL 188

Query: 152 KFRIKGSIQR--MKQNLMGIQTDSIDLREKMRRELTLGQIRSSTMSNPDHFPQLLLPKDQ 209
           K + KG+ +   ++  L G+     D   K       G +       P  +P    P+  
Sbjct: 189 KAKYKGTPEAAVLRTPLPGVIPARPDGEPK-------GPLPD--FPYPYQYPAAPGPRAP 239

Query: 210 VSGKAVCL---IEEISSTEIQVEMKMPAYELKIVHDHSEKPLKIELKVELPGINSVSLCD 266
              +A       E   S   +  + +  Y        S  P ++ + +ELP + S     
Sbjct: 240 SPPEAALQPAPTEPRYSVVQRHHVDLQDYRCSRDSAPSPVPHELVITIELPLLRSAEQAA 299

Query: 267 LSVSEDDLLIEVSEK-YRLHLNLPKLIDTEMTTAKFIKEKSTLIITMPLV 315
           L V+   L ++  +  YRL L+LP  +D     A+F K +  L++T+P+V
Sbjct: 300 LEVTRKLLCLDSRKPDYRLRLSLPYPVDDGRGKAQFNKARRQLVVTLPVV 349


>gi|4759082 serum deprivation response protein [Homo sapiens]
          Length = 425

 Score = 33.9 bits (76), Expect = 0.19
 Identities = 71/318 (22%), Positives = 125/318 (39%), Gaps = 44/318 (13%)

Query: 1   METSSKGLLTQVTQFWNLLDDLAQSDPEGYEKFIQQQLKEGKQLCAAPE--PQLCLQTRI 58
           +E S KG+   +T+    L     S      K +++  K      A  E   + C Q + 
Sbjct: 86  LEGSVKGIQNDLTK----LSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMDRQCAQVKR 141

Query: 59  LKPKE---------KILFINLCQWTRIPAPQSTTHPVPLTV-GK---PEDTTEISDAYTV 105
           L+            K+L     +   IPA      PV   V GK   P++   + +    
Sbjct: 142 LENNHAQLLRRNHFKVLIFQ--EENEIPASVFVKQPVSGAVEGKEELPDENKSLEETLHT 199

Query: 106 IDVAYNPDVLHAAEKDQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQN 165
           +D++ + D+ H  E  +    + ++ +    E+  + +L     + K   + +I++ K N
Sbjct: 200 VDLSSDDDLPHDEEALEDSAEEKVEESRA--EKIKRSSLKKVDSLKKAFSRQNIEK-KMN 256

Query: 166 LMGIQTDSIDLREKMRRELTLG-QIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISST 224
            +G +  S++ REK+++ LT   Q  SS  S+P     L   + +V         E  S 
Sbjct: 257 KLGTKIVSVERREKIKKSLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSE 316

Query: 225 EIQVEMKMP--AYELKIVHDHSEKPLKIEL-----------KVELPGINS--VSLCDLSV 269
           ++    +MP    E      HSE  L   L           K    G NS   S  DL++
Sbjct: 317 DLPSSEQMPNDQEEESFAEGHSEASLASALVEGEIAEEAAEKATSRGSNSGMDSNIDLTI 376

Query: 270 SEDD----LLIEVSEKYR 283
            ED+    + +E ++K R
Sbjct: 377 VEDEEEESVALEQAQKVR 394


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 42/191 (21%), Positives = 73/191 (38%), Gaps = 32/191 (16%)

Query: 116  HAAEKDQVKKNQLIQMAMKCIEEKFQFTLSHSYHITKFRIKGSIQRMKQNLMGIQTDSID 175
            H AE+ + K+ +L QM  K   EK                 G + ++++ +  +QT   D
Sbjct: 1087 HLAEELRKKELELSQMNSKVENEK-----------------GLVAQLQKTVKELQTQIKD 1129

Query: 176  LREKMRRE-LTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTEIQVEMKMPA 234
            L+EK+  E  T  ++             L    ++V G ++  +E     E + +     
Sbjct: 1130 LKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRD 1189

Query: 235  YELKIVH-DHSEKPLK-------IELKVELPGINSV------SLCDLSVSEDDLLIEVSE 280
             E   +H + +   LK        EL+ ++  +  V         DL +  DDLL  V +
Sbjct: 1190 MEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQ 1249

Query: 281  KYRLHLNLPKL 291
              R   N  KL
Sbjct: 1250 MTRAKANAEKL 1260


>gi|33859793 hypothetical protein LOC139212 [Homo sapiens]
          Length = 214

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 2/62 (3%)

Query: 253 KVELPGINSVSLCDLSVSEDDLLIEVSEKYRLHLNLPKLIDTEMTTAKFIKEKSTLIITM 312
           K++LP  N   +  + + E  L +   +K +L + LP+L++     A +I E  TL ITM
Sbjct: 145 KIKLPNTNPSDI-QIDIQETILDLRTPQK-KLLITLPELVECTSAKAFYIPETETLEITM 202

Query: 313 PL 314
            +
Sbjct: 203 TM 204


>gi|38261962 activating transcription factor 7 interacting protein
           [Homo sapiens]
          Length = 1270

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 163 KQNLMGIQTDSIDLREKMRRELTLGQIRSSTMSNPDHFPQLLLPKDQVSG-----KAVCL 217
           K +L+ I   + DL EKM         + S+ S P     +L  ++ +SG     + +  
Sbjct: 454 KTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQ 513

Query: 218 IEEISSTEIQVEMK--MPAYELKIVHDHSEKP 247
            E  S  E++   K   P  E +++H+  E+P
Sbjct: 514 NETCSPAEVESNEKDNKPEEEEQVIHEDDERP 545


>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
           exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 20/79 (25%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 69  NLCQWTRIPAPQSTT-HPVPLTVGKPEDTTEISDAYTVIDVAY-NPDVLHAAEKDQVKKN 126
           +L + T +   QS +   +P  + +     + SD+ +V D+ Y NP  +   +  Q +  
Sbjct: 335 DLQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQSSQKEGT 394

Query: 127 QLIQMAMKCIEEKFQFTLS 145
            L+   + CI E F+F +S
Sbjct: 395 ALVPYGLPCIRELFRFLIS 413


>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
          Length = 762

 Score = 29.6 bits (65), Expect = 3.6
 Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 13/122 (10%)

Query: 109 AYNPDVLHAAEKDQVKKNQLIQMAMKCIEEKFQFTLS-HSYHITKF--RIKGSIQRMKQN 165
           A   + L   + D  KK    ++ ++ I E  +  L  HS  + K   R+KG  + +   
Sbjct: 399 AQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNL 458

Query: 166 LMGIQTDSIDLREKMRRELTLGQIRSSTMSNPDHFPQLLLPKDQVSGKAVCLIEEISSTE 225
               Q +S   REK +R  TL +  +   +  DH  Q    KD           E+ STE
Sbjct: 459 KKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKD----------SELKSTE 508

Query: 226 IQ 227
           +Q
Sbjct: 509 LQ 510


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 21/78 (26%), Positives = 32/78 (41%)

Query: 47   APEPQLCLQTRILKPKEKILFINLCQWTRIPAPQSTTHPVPLTVGKPEDTTEISDAYTVI 106
            +P PQ   Q    KP   I   +  +  R+    +T   VP+ +   E   E     ++ 
Sbjct: 1171 SPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLA 1230

Query: 107  DVAYNPDVLHAAEKDQVK 124
              A  P + H  EKDQ+K
Sbjct: 1231 CPAEPPALPHGLEKDQIK 1248


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,566,647
Number of Sequences: 37866
Number of extensions: 525480
Number of successful extensions: 1700
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1692
Number of HSP's gapped (non-prelim): 14
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.