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Search of human proteins with 19923907
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923907 oxidoreductase NAD-binding domain containing 1
[Homo sapiens]
(312 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo... 627 e-180
gi|47778923 cytochrome b5 reductase b5R.2 [Homo sapiens] 49 7e-06
gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens] 41 0.001
gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens] 41 0.001
gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens] 41 0.001
gi|49574502 cytochrome b5 reductase 1 [Homo sapiens] 40 0.003
gi|84875541 cytochrome b5 reductase 4 [Homo sapiens] 32 0.55
gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] 30 2.1
gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] 30 2.1
gi|194018539 myosin binding protein H-like [Homo sapiens] 30 3.6
gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Hom... 29 4.7
gi|20149640 dual oxidase 1 precursor [Homo sapiens] 29 6.1
gi|28872751 dual oxidase 1 precursor [Homo sapiens] 29 6.1
gi|85797660 limkain b1 [Homo sapiens] 29 6.1
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 28 8.0
gi|117168263 RasGEF domain family, member 1A [Homo sapiens] 28 8.0
>gi|19923907 oxidoreductase NAD-binding domain containing 1 [Homo
sapiens]
Length = 312
Score = 627 bits (1616), Expect = e-180
Identities = 312/312 (100%), Positives = 312/312 (100%)
Query: 1 MACAAVMIPGLLRCSVGAIRIEAASLRLTLSTLRHLTLTSIMKSKRKTDHMERTASVLRR 60
MACAAVMIPGLLRCSVGAIRIEAASLRLTLSTLRHLTLTSIMKSKRKTDHMERTASVLRR
Sbjct: 1 MACAAVMIPGLLRCSVGAIRIEAASLRLTLSTLRHLTLTSIMKSKRKTDHMERTASVLRR 60
Query: 61 EIVSAAKVCGAASESPSVKSLRLLVADQDFSFKAGQWVDFFIPGVSVVGGFSICSSPRLL 120
EIVSAAKVCGAASESPSVKSLRLLVADQDFSFKAGQWVDFFIPGVSVVGGFSICSSPRLL
Sbjct: 61 EIVSAAKVCGAASESPSVKSLRLLVADQDFSFKAGQWVDFFIPGVSVVGGFSICSSPRLL 120
Query: 121 EQERVIELAVKYTNHPPALWVHNTCTLDCEVAVRVGGEFFFDPQPADASRNLVLIAGGVG 180
EQERVIELAVKYTNHPPALWVHNTCTLDCEVAVRVGGEFFFDPQPADASRNLVLIAGGVG
Sbjct: 121 EQERVIELAVKYTNHPPALWVHNTCTLDCEVAVRVGGEFFFDPQPADASRNLVLIAGGVG 180
Query: 181 INPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNILDLVNEFPEKIA 240
INPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNILDLVNEFPEKIA
Sbjct: 181 INPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNILDLVNEFPEKIA 240
Query: 241 CSLHVTKQTTQINAELKPYITEGRITEKEIRDHISKETLFYICGPPPMTDFFSKQLENNH 300
CSLHVTKQTTQINAELKPYITEGRITEKEIRDHISKETLFYICGPPPMTDFFSKQLENNH
Sbjct: 241 CSLHVTKQTTQINAELKPYITEGRITEKEIRDHISKETLFYICGPPPMTDFFSKQLENNH 300
Query: 301 VPKEHICFEKWW 312
VPKEHICFEKWW
Sbjct: 301 VPKEHICFEKWW 312
>gi|47778923 cytochrome b5 reductase b5R.2 [Homo sapiens]
Length = 276
Score = 48.5 bits (114), Expect = 7e-06
Identities = 30/121 (24%), Positives = 63/121 (52%), Gaps = 18/121 (14%)
Query: 171 NLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNILD 230
+L +IAGG GI P+L ++RH + ++ +++ + L ++ + ++L +K + +
Sbjct: 149 HLGMIAGGTGITPMLQLIRH---ITKDPSDRTR------MSLIFANQTEEDILVRKELEE 199
Query: 231 LVNEFPEKIACSLHVTKQTTQINAELKPYITEGRITEKEIRDHI---SKETLFYICGPPP 287
+ P++ +L T I + + G +T I++H+ +K TL +CGPPP
Sbjct: 200 IARTHPDQF--NLWYTLDRPPIGWK----YSSGFVTADMIKEHLPPPAKSTLILVCGPPP 253
Query: 288 M 288
+
Sbjct: 254 L 254
>gi|4503327 cytochrome b5 reductase 3 isoform m [Homo sapiens]
Length = 301
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 18/125 (14%)
Query: 170 RNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNIL 229
+++ +IAGG GI P+L ++R A ++ + L ++ + ++L + +
Sbjct: 173 KSVGMIAGGTGITPMLQVIR---------AIMKDPDDHTVCHLLFANQTEKDILLRPELE 223
Query: 230 DLVNEFPEKIACSLHVTKQTTQINAELKPYITEGRITEKEIRDHI---SKETLFYICGPP 286
+L N+ + T E Y +G + E+ IRDH+ +E L +CGPP
Sbjct: 224 ELRNKHSARFK-----LWYTLDRAPEAWDY-GQGFVNEEMIRDHLPPPEEEPLVLMCGPP 277
Query: 287 PMTDF 291
PM +
Sbjct: 278 PMIQY 282
>gi|193794826 cytochrome b5 reductase 3 isoform s [Homo sapiens]
Length = 278
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 18/125 (14%)
Query: 170 RNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNIL 229
+++ +IAGG GI P+L ++R A ++ + L ++ + ++L + +
Sbjct: 150 KSVGMIAGGTGITPMLQVIR---------AIMKDPDDHTVCHLLFANQTEKDILLRPELE 200
Query: 230 DLVNEFPEKIACSLHVTKQTTQINAELKPYITEGRITEKEIRDHI---SKETLFYICGPP 286
+L N+ + T E Y +G + E+ IRDH+ +E L +CGPP
Sbjct: 201 ELRNKHSARFK-----LWYTLDRAPEAWDY-GQGFVNEEMIRDHLPPPEEEPLVLMCGPP 254
Query: 287 PMTDF 291
PM +
Sbjct: 255 PMIQY 259
>gi|6552328 cytochrome b5 reductase 3 isoform s [Homo sapiens]
Length = 278
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 18/125 (14%)
Query: 170 RNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNIL 229
+++ +IAGG GI P+L ++R A ++ + L ++ + ++L + +
Sbjct: 150 KSVGMIAGGTGITPMLQVIR---------AIMKDPDDHTVCHLLFANQTEKDILLRPELE 200
Query: 230 DLVNEFPEKIACSLHVTKQTTQINAELKPYITEGRITEKEIRDHI---SKETLFYICGPP 286
+L N+ + T E Y +G + E+ IRDH+ +E L +CGPP
Sbjct: 201 ELRNKHSARFK-----LWYTLDRAPEAWDY-GQGFVNEEMIRDHLPPPEEEPLVLMCGPP 254
Query: 287 PMTDF 291
PM +
Sbjct: 255 PMIQY 259
>gi|49574502 cytochrome b5 reductase 1 [Homo sapiens]
Length = 305
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 21/130 (16%)
Query: 163 PQPADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSEL 222
P+P A + L +IAGG GI P+L ++R + + L ++ + ++
Sbjct: 171 PEPRVAKK-LGMIAGGTGITPMLQLIRAILKVPEDPTQ---------CFLLFANQTEKDI 220
Query: 223 LFKKNILDLVNEFPEKIACSLHVTKQTTQINAELKPY-ITEGRITEKEIRDHI---SKET 278
+ ++++ +L +P + K ++ K + ++G +T IR+H+ +
Sbjct: 221 ILREDLEELQARYPNRF-------KLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDV 273
Query: 279 LFYICGPPPM 288
L +CGPPPM
Sbjct: 274 LVLLCGPPPM 283
>gi|84875541 cytochrome b5 reductase 4 [Homo sapiens]
Length = 521
Score = 32.3 bits (72), Expect = 0.55
Identities = 29/136 (21%), Positives = 64/136 (47%), Gaps = 11/136 (8%)
Query: 171 NLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNILD 230
+L L+A G G P++ IL +A L + + R +KL + K +++++ +
Sbjct: 392 DLFLLAAGTGFTPMVKILNYA---LTDIPSLRK------VKLMFFNKTEDDIIWRSQLEK 442
Query: 231 LVNEFPEKIACSLHVTKQTTQINAELKPYITEGRITEKEIRDHISKETLFYICGPPPMTD 290
L + +++ ++ ++ N + + +I+ ++E R+ + L ICGP P T+
Sbjct: 443 LAFK-DKRLDVEFVLSAPISEWNGK-QGHISPALLSEFLKRNLDKSKVLVCICGPVPFTE 500
Query: 291 FFSKQLENNHVPKEHI 306
+ L + + K I
Sbjct: 501 QGVRLLHDLNFSKNEI 516
>gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens]
Length = 698
Score = 30.4 bits (67), Expect = 2.1
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 5/65 (7%)
Query: 165 PADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTS-ELL 223
P D S ++++ G GI P + L+H + L+EQ N G + LF+ ++ + L
Sbjct: 533 PDDPSIPIIMVGPGTGIAPFIGFLQH-REKLQEQHPDGN---FGAMWLFFGCRHKDRDYL 588
Query: 224 FKKNI 228
F+K +
Sbjct: 589 FRKEL 593
>gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens]
Length = 725
Score = 30.4 bits (67), Expect = 2.1
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 5/65 (7%)
Query: 165 PADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTS-ELL 223
P D S ++++ G GI P + L+H + L+EQ N G + LF+ ++ + L
Sbjct: 560 PDDPSIPIIMVGPGTGIAPFIGFLQH-REKLQEQHPDGN---FGAMWLFFGCRHKDRDYL 615
Query: 224 FKKNI 228
F+K +
Sbjct: 616 FRKEL 620
>gi|194018539 myosin binding protein H-like [Homo sapiens]
Length = 354
Score = 29.6 bits (65), Expect = 3.6
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 6/59 (10%)
Query: 136 PPALWVHNTCTLDC-EVAVRVGGE----FFFDPQPADASR-NLVLIAGGVGINPLLSIL 188
P A+W H+ C LD V+VR G + F + Q AD+ R L + GG+ + IL
Sbjct: 83 PQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDIL 141
>gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Homo
sapiens]
Length = 747
Score = 29.3 bits (64), Expect = 4.7
Identities = 14/41 (34%), Positives = 21/41 (51%)
Query: 149 CEVAVRVGGEFFFDPQPADASRNLVLIAGGVGINPLLSILR 189
C + + G + + AS + VLI G+GI P SIL+
Sbjct: 543 CNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQ 583
>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 28.9 bits (63), Expect = 6.1
Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 3/105 (2%)
Query: 88 QDFSFKAGQWVDF--FIPGVSVVGGFSICSSPRLLEQERVIELAVKYTNHPPALWVHNTC 145
Q F +K+GQWV G + F++ S+P I A +T ++ T
Sbjct: 1296 QGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTG 1355
Query: 146 TLDCEVA-VRVGGEFFFDPQPADASRNLVLIAGGVGINPLLSILR 189
+ + G F Q VL+ GG+G+ P SIL+
Sbjct: 1356 DRCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILK 1400
>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 28.9 bits (63), Expect = 6.1
Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 3/105 (2%)
Query: 88 QDFSFKAGQWVDF--FIPGVSVVGGFSICSSPRLLEQERVIELAVKYTNHPPALWVHNTC 145
Q F +K+GQWV G + F++ S+P I A +T ++ T
Sbjct: 1296 QGFEYKSGQWVRIACLALGTTEYHPFTLTSAPHEDTLSLHIRAAGPWTTRLREIYSAPTG 1355
Query: 146 TLDCEVA-VRVGGEFFFDPQPADASRNLVLIAGGVGINPLLSILR 189
+ + G F Q VL+ GG+G+ P SIL+
Sbjct: 1356 DRCARYPKLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILK 1400
>gi|85797660 limkain b1 [Homo sapiens]
Length = 1742
Score = 28.9 bits (63), Expect = 6.1
Identities = 18/72 (25%), Positives = 33/72 (45%)
Query: 165 PADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLF 224
P + S + + GG G + S L H LL Q+ + ++G+ F SA +
Sbjct: 106 PNEPSTSPMRFGGGGGGSGGTSSLIHPGALLDSQSTRTITCQVGSGFAFQSASSLQNASA 165
Query: 225 KKNILDLVNEFP 236
+ N+ + ++FP
Sbjct: 166 RNNLAGIASDFP 177
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 28.5 bits (62), Expect = 8.0
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 8/70 (11%)
Query: 36 LTLTSIMKSKRKTDHMERTASVLRREIVSAAKVCGAASESP-SVKSLRLLVADQDFSFKA 94
L T K +K + + SVL KV G P +++L+ +A SF
Sbjct: 3162 LEATKPEKHPKKEEKISSALSVL-------GKVVGETHVDPIQLQALQNAIAGDPASFIG 3214
Query: 95 GQWVDFFIPG 104
GQ++ +FIPG
Sbjct: 3215 GQFLPYFIPG 3224
>gi|117168263 RasGEF domain family, member 1A [Homo sapiens]
Length = 481
Score = 28.5 bits (62), Expect = 8.0
Identities = 9/22 (40%), Positives = 15/22 (68%)
Query: 291 FFSKQLENNHVPKEHICFEKWW 312
+F ++ NH+P HI F+K+W
Sbjct: 390 YFLHKIHTNHLPNGHINFKKFW 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,749,799
Number of Sequences: 37866
Number of extensions: 472776
Number of successful extensions: 984
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 972
Number of HSP's gapped (non-prelim): 16
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.