Search of human proteins with 19923233

Search of human proteins with 19923233

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo
sapiens]
         (547 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo ...  1103   0.0  
gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]         626   e-179
gi|55956777 sterol carrier protein 2 isoform 1 precursor [Homo s...   286   3e-77
gi|55956779 sterol carrier protein 2 isoform 2 precursor [Homo s...   275   6e-74
gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]     89   1e-17
gi|55956781 sterol carrier protein 2 isoform 3 precursor [Homo s...    85   1e-16
gi|30425406 hypothetical protein LOC140856 [Homo sapiens]              78   2e-14
gi|40254986 hydroxysteroid dehydrogenase like 2 [Homo sapiens]         67   4e-11
gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]        65   2e-10
gi|4501853 acetyl-Coenzyme A acyltransferase 1 isoform a [Homo s...    64   5e-10
gi|148539872 acetyl-Coenzyme A acetyltransferase 2 [Homo sapiens]      59   9e-09
gi|4504327 mitochondrial trifunctional protein, beta subunit pre...    54   4e-07
gi|20149563 stomatin (EPB72)-like 1 [Homo sapiens]                     54   5e-07
gi|194353979 acetyl-Coenzyme A acyltransferase 1 isoform b [Homo...    50   7e-06
gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo...    47   4e-05
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]                 33   0.51 
gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]      33   0.88 
gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens]      30   5.7  
gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]      30   5.7  
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be...    29   9.7  

>gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo
           sapiens]
          Length = 547

 Score = 1103 bits (2853), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60
           MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA
Sbjct: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60

Query: 61  CVGYVFGDSTCGQRAIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALG 120
           CVGYVFGDSTCGQRAIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALG
Sbjct: 61  CVGYVFGDSTCGQRAIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALG 120

Query: 121 FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH 180
           FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH
Sbjct: 121 FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH 180

Query: 181 FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA 240
           FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA
Sbjct: 181 FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA 240

Query: 241 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 300
           FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID
Sbjct: 241 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 300

Query: 301 VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT 360
           VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT
Sbjct: 301 VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT 360

Query: 361 GLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIE 420
           GLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIE
Sbjct: 361 GLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIE 420

Query: 421 AVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKN 480
           AVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKN
Sbjct: 421 AVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKN 480

Query: 481 GKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQL 540
           GKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQL
Sbjct: 481 GKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQL 540

Query: 541 QPGNAKL 547
           QPGNAKL
Sbjct: 541 QPGNAKL 547


>gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]
          Length = 322

 Score =  626 bits (1614), Expect = e-179
 Identities = 318/366 (86%), Positives = 319/366 (87%), Gaps = 44/366 (12%)

Query: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60
           MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA
Sbjct: 1   MSSSPWEPATLRRVFVVGVGMTKFVKPGAENSRDYPDLAEEAGKKALADAQIPYSAVDQA 60

Query: 61  CVGYVFGDSTCGQRAIYHSLGMTGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALG 120
           CVGYVFG                                            VAECVLALG
Sbjct: 61  CVGYVFG--------------------------------------------VAECVLALG 76

Query: 121 FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH 180
           FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH
Sbjct: 77  FEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIEH 136

Query: 181 FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA 240
           FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA
Sbjct: 137 FAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEA 196

Query: 241 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 300
           FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID
Sbjct: 197 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 256

Query: 301 VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT 360
           VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT
Sbjct: 257 VIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGAT 316

Query: 361 GLAQCA 366
           G   C+
Sbjct: 317 GGHSCS 322


>gi|55956777 sterol carrier protein 2 isoform 1 precursor [Homo
           sapiens]
          Length = 143

 Score =  286 bits (732), Expect = 3e-77
 Identities = 143/143 (100%), Positives = 143/143 (100%)

Query: 405 MGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVK 464
           MGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVK
Sbjct: 1   MGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVK 60

Query: 465 DGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLK 524
           DGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLK
Sbjct: 61  DGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLK 120

Query: 525 ITGNMGLAMKLQNLQLQPGNAKL 547
           ITGNMGLAMKLQNLQLQPGNAKL
Sbjct: 121 ITGNMGLAMKLQNLQLQPGNAKL 143


>gi|55956779 sterol carrier protein 2 isoform 2 precursor [Homo
           sapiens]
          Length = 140

 Score =  275 bits (704), Expect = 6e-74
 Identities = 140/143 (97%), Positives = 140/143 (97%), Gaps = 3/143 (2%)

Query: 405 MGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVK 464
           MGFPEAA   RTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVK
Sbjct: 1   MGFPEAA---RTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVK 57

Query: 465 DGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLK 524
           DGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLK
Sbjct: 58  DGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLK 117

Query: 525 ITGNMGLAMKLQNLQLQPGNAKL 547
           ITGNMGLAMKLQNLQLQPGNAKL
Sbjct: 118 ITGNMGLAMKLQNLQLQPGNAKL 140


>gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
          Length = 736

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 45/114 (39%), Positives = 70/114 (61%), Gaps = 2/114 (1%)

Query: 424 TSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKG 483
           T S     ++  VF+EI ++L++ G + VKK+  +F + +  G G   A W +D+K+G G
Sbjct: 615 TPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKG-GNIGAKWTIDLKSGSG 673

Query: 484 SVLPNSDK-KADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQ 536
            V     K  AD TI ++D DF+ ++ GK++PQ AFF G+LK  GN+ L+ KLQ
Sbjct: 674 KVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQ 727


>gi|55956781 sterol carrier protein 2 isoform 3 precursor [Homo
           sapiens]
          Length = 59

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 42/42 (100%), Positives = 42/42 (100%)

Query: 405 MGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEE 446
           MGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEE
Sbjct: 1   MGFPEAASSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEE 42


>gi|30425406 hypothetical protein LOC140856 [Homo sapiens]
          Length = 156

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 42/119 (35%), Positives = 65/119 (54%), Gaps = 2/119 (1%)

Query: 421 AVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKN 480
           A+P       F++  VF++I   + E G Q VKK+  +F   +    G     W +D+KN
Sbjct: 32  AMPHPLELSEFESFPVFQDIRLHIREVGAQLVKKVNAVFQLDITKN-GKTILRWTIDLKN 90

Query: 481 GKGSVLPNSDK-KADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNL 538
           G G + P   +  AD   T+ +S F+ L+ GKMNPQ AF  GK K++G + L+ KL+ +
Sbjct: 91  GSGDMYPGPARLPADTVFTIPESVFMELVLGKMNPQKAFLAGKFKVSGKVLLSWKLERV 149


>gi|40254986 hydroxysteroid dehydrogenase like 2 [Homo sapiens]
          Length = 418

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 45/131 (34%), Positives = 70/131 (53%), Gaps = 13/131 (9%)

Query: 418 QIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVD 477
           Q++  P S A +       F+ ++  L ++    VK    I+ F++    GG   TW +D
Sbjct: 300 QLQPKPRSGAVEE-----TFRIVKDSLSDD---VVKATQAIYLFELSGEDGG---TWFLD 348

Query: 478 VKNGKGSV-LPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQ 536
           +K+  G+V       +AD  ++M   DF+ + +GK+ P  AF  GKLKI GNM LA+KL+
Sbjct: 349 LKSKGGNVGYGEPSDQADVVMSMTTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLE 408

Query: 537 NLQLQPGNAKL 547
            L  Q  NA+L
Sbjct: 409 KLMNQM-NARL 418


>gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]
          Length = 397

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 112/424 (26%), Positives = 162/424 (38%), Gaps = 92/424 (21%)

Query: 9   ATLRRVFVVGVGMTKFVKPGAENSRDYP--DLAEEAGKKALADAQIPYSAVDQACVGYVF 66
           A LR VFVV    T F   G    +D+   DL+E A K AL+  ++    VD   +G V 
Sbjct: 2   ALLRGVFVVAAKRTPFGAYGGL-LKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60

Query: 67  GDSTCGQRAIYHSLGMTGIP----IINVNNNCATGSTALFMARQLIQGGVAECVLALGFE 122
             S+       H     GIP     + +N  C +G  ++    Q I    AE VL  G E
Sbjct: 61  QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120

Query: 123 KMSKG-----------SLG--IKFSDR--TIPTDKHVDLLINKYGLSAHPVAPQMFGYAG 167
            MS+             LG  IK  D      TD+HV L +    ++A  +A +      
Sbjct: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPM---AMTAENLAVKH--KIS 175

Query: 168 KEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASK-----EVFDF---- 218
           +E  +KY  + +      WK       N    F DE +  EV   K     +V +     
Sbjct: 176 REECDKYALQSQQ----RWK-----AANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQ 226

Query: 219 --LTILQCCP----------------TSDGAAAAILASEAFVQKYGLQSKAVEILAQEMM 260
             L  LQ  P                 +DGA A I+ASE  V+K+     A  I+   + 
Sbjct: 227 TTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLA-RIVGYFVS 285

Query: 261 TDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALG 320
              PS      +  + G            +K+GL+  D+D++E+++ F+   L    +L 
Sbjct: 286 GCDPSIMGIGPVPAISG----------ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLD 335

Query: 321 LCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQ 380
           L                       N +GG I+ GHPLG +G    A L  +LR   GK  
Sbjct: 336 LDISKT------------------NVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYA 377

Query: 381 VPGA 384
           V  A
Sbjct: 378 VGSA 381


>gi|4501853 acetyl-Coenzyme A acyltransferase 1 isoform a [Homo
           sapiens]
          Length = 424

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 83/338 (24%), Positives = 137/338 (40%), Gaps = 56/338 (16%)

Query: 85  IPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMSKGSLGI--KFSDRTIPTDK 142
           +P+  VN  C++G  A+      I+ G  +  +A G E MS    G     + R +  +K
Sbjct: 114 VPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEK 173

Query: 143 HVDLLINKYGLSAHPVAPQM---------FGYAGKEHMEKYGTKIEHFAKI--------G 185
             D LI   G+++  VA +          F  A ++   +  +K    A+I         
Sbjct: 174 ARDCLI-PMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHD 232

Query: 186 WKNHKHSVNNPYSQ-FQDEYSLDEVMASKEVFD---FLTILQCCPTSDGAAAAILASEAF 241
            K  K S+     +  +   +++ +   K  F      T       SDGAAA +LA  + 
Sbjct: 233 DKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSK 292

Query: 242 VQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDV 301
            ++ GL    + +L    +  +P        I  +G      A     +K+GLT +D+D+
Sbjct: 293 AEELGLP--ILGVLRSYAVVGVPPD------IMGIG---PAYAIPVALQKAGLTVSDVDI 341

Query: 302 IELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATG 361
            E+++ F++      E L L PE                   +NP GG ++ GHPLG TG
Sbjct: 342 FEINEAFASQAAYCVEKLRLPPEK------------------VNPLGGAVALGHPLGCTG 383

Query: 362 LAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVV 399
             Q   L  +L+   GKR      V++    G+G A V
Sbjct: 384 ARQVITLLNELK-RRGKRAY--GVVSMCIGTGMGAAAV 418


>gi|148539872 acetyl-Coenzyme A acetyltransferase 2 [Homo sapiens]
          Length = 397

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 85/360 (23%), Positives = 137/360 (38%), Gaps = 67/360 (18%)

Query: 37  DLAEEAGKKALADAQIPYSAVDQACVGYVFGDSTCGQRAIYHSLGMTGIPII----NVNN 92
           DL     K+ L  A +    V +   G+V   + CGQ  +  +    GIP      +   
Sbjct: 32  DLGSTVIKEVLKRATVAPEDVSEVIFGHVLA-AGCGQNPVRQASVGAGIPYSVPAWSCQM 90

Query: 93  NCATGSTALFMARQLIQGGVAECVLALGFEKMSKGS------LGIKFSDRTIPTDKHVDL 146
            C +G  A+ +A Q I  G +  V+A G E MSK         G+K  +  +      D 
Sbjct: 91  ICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDG 150

Query: 147 LINKY-----GLSAHPVAPQMFGYAGKEHMEKYGT----------KIEHFAK----IGWK 187
           L + +     G++A  VA +      +E  +K             K  HF K    +   
Sbjct: 151 LTDAFHNCHMGITAENVAKKW--QVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVS 208

Query: 188 NHKHSVNNPYSQFQDEYSLDEVMASKEVFDF------LTILQCCPTSDGAAAAILASEAF 241
             K  +     +F    S  E M+  + +        +T       +DGAAA +L  ++ 
Sbjct: 209 TRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSE 268

Query: 242 VQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDV 301
             K GL   A  +   ++         E SI+ +      K+A  K    +G +  D+D+
Sbjct: 269 ADKRGLTPLARIVSWSQVGV-------EPSIMGIGPIPAIKQAVTK----AGWSLEDVDI 317

Query: 302 IELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATG 361
            E+++ F+       + LGL PE                   +N  GG I+ GHPLGA+G
Sbjct: 318 FEINEAFAAVSAAIVKELGLNPE------------------KVNIEGGAIALGHPLGASG 359


>gi|4504327 mitochondrial trifunctional protein, beta subunit
           precursor [Homo sapiens]
          Length = 474

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 107/449 (23%), Positives = 159/449 (35%), Gaps = 83/449 (18%)

Query: 11  LRRVFVVGVGMTKFVKPGAENSRDYP-DLAEEAGKKALADAQIPYSAVDQACVGYVFGDS 69
           +R V VV    T F+  G       P DLA  A    L    +P   VD    G V  + 
Sbjct: 51  IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110

Query: 70  TCGQRAIYHSLGM---TGIPIINVNNNCATGSTALFMARQLIQGGVAECVLALGFEKMSK 126
                A   +LG       P   V   C + + A+     LI  G  + ++A G E MS 
Sbjct: 111 KTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSD 170

Query: 127 GSLGIKFSDRTIPTDKHVDL-------LINKYGLSAHPVAPQMFGYAGKEHMEKYGTKIE 179
             +      R +  D +          LI+K+  +   +AP++   +     E  G   +
Sbjct: 171 VPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNF--LAPELPAVSEFSTSETMGHSAD 228

Query: 180 HFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCP---------TSDG 230
             A     +            QDEY+L     +K+  D   +    P         T D 
Sbjct: 229 RLAAAFAVSRLE---------QDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDN 279

Query: 231 AAAAILASE------AFVQKYGLQS-----------KAVEILAQEMMTDLPSSFEEKSII 273
                   +      AF++ YG  +            A+ I+A+E    L   ++ K+ +
Sbjct: 280 GIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKA--LAMGYKPKAYL 337

Query: 274 K---MVGFDMSKE-------AARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCP 323
           +    V  D   +       A  K  EK+GLT NDID  E H+ FS   L  ++A+    
Sbjct: 338 RDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMD--- 394

Query: 324 EGQGATLVDRGDNTYGGKWV---------INPSGGLISKGHPLGATGLAQCAELCWQLRG 374
                   D     Y G+            N  GG +S GHP GATG         +LR 
Sbjct: 395 -------SDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRK 447

Query: 375 EAGKRQVPGAKVALQHNLGIGGAVVVTLY 403
           E G+  +  A  A     G G A++V  Y
Sbjct: 448 EGGQYGLVAACAA----GGQGHAMIVEAY 472


>gi|20149563 stomatin (EPB72)-like 1 [Homo sapiens]
          Length = 398

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 28/89 (31%), Positives = 50/89 (56%), Gaps = 2/89 (2%)

Query: 449 EQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPN-SDKKADCTITMADSDFLAL 507
           E  V ++G  + F V   P G ++ + +D+  G+G V     D   D  + MA++D  AL
Sbjct: 304 EALVSQVGACYQFNVVL-PSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLRAL 362

Query: 508 MTGKMNPQSAFFQGKLKITGNMGLAMKLQ 536
           +  ++ P  A+  G+LK+ G++ +AMKL+
Sbjct: 363 LCRELRPLGAYMSGRLKVKGDLAMAMKLE 391


>gi|194353979 acetyl-Coenzyme A acyltransferase 1 isoform b [Homo
           sapiens]
          Length = 331

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 21/108 (19%)

Query: 292 SGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLI 351
           +GLT +D+D+ E+++ F++      E L L PE                   +NP GG +
Sbjct: 239 AGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEK------------------VNPLGGAV 280

Query: 352 SKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVV 399
           + GHPLG TG  Q   L  +L+   GKR      V++    G+G A V
Sbjct: 281 ALGHPLGCTGARQVITLLNELK-RRGKRAY--GVVSMCIGTGMGAAAV 325


>gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo
           sapiens]
          Length = 427

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 93/396 (23%), Positives = 146/396 (36%), Gaps = 79/396 (19%)

Query: 46  ALADAQIPYSAVDQACVGYVFGDSTCGQRAIYHSLGMTGIPI----INVNNNCATGSTAL 101
           A+  A IP   V +A +G V      GQ     ++   G+PI      +N  CA+G  A+
Sbjct: 75  AIEKAGIPKEEVKEAYMGNVLQGGE-GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAI 133

Query: 102 FMARQLIQGGVAECVLALGFEKMS-------KGSL---GIKFSDRTIPTDKHVDLLINK- 150
            MA Q +  G  + ++A G E MS       +GS    G+K  D  I  D   D + NK 
Sbjct: 134 MMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLED-LIVKDGLTD-VYNKI 191

Query: 151 -YGLSAHPVAPQMFGYAGKEHMEKYGTKIEHFAKIGWKNHKHSVN------------NPY 197
             G  A   A ++     +   + Y       +K  W+  K                +  
Sbjct: 192 HMGSCAENTAKKL--NIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVV 249

Query: 198 SQFQDEY---SLDEVMASKEVFD----FLTILQCCPTSDGAAAAILASEAFVQKYGLQSK 250
            +  +EY      +V   K VF      +T       +DGAAA +L +    ++  +   
Sbjct: 250 VKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPL 309

Query: 251 AVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFST 310
           A  I+A       P  F    +           AA    +  GL   DI + E+++ FS 
Sbjct: 310 A-RIVAFADAAVEPIDFPIAPVY----------AASMVLKDVGLKKEDIAMWEVNEAFSL 358

Query: 311 NELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCW 370
             L   + L + P+                   +N +GG +S GHP+G +G      L  
Sbjct: 359 VVLANIKMLEIDPQ------------------KVNINGGAVSLGHPIGMSGARIVGHLTH 400

Query: 371 QLR-GEAGKRQVPGAKVALQHNLGIGGAVVVTLYKM 405
            L+ GE G   +           G GGA  + + K+
Sbjct: 401 ALKQGEYGLASICN---------GGGGASAMLIQKL 427


>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
          Length = 775

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%)

Query: 419 IEAVPTSSASDGFKANLVFKEIE-KKLEEEGEQFVKKIGGIFAFK-VKDGPGGKE 471
           +E +P+S A+DG KA  ++ + E K+L+EE E++  +   +   K  KDG  GKE
Sbjct: 462 LEIMPSSEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKE 516


>gi|93141018 H2A histone family, member Y isoform 3 [Homo sapiens]
          Length = 372

 Score = 32.7 bits (73), Expect = 0.88
 Identities = 46/187 (24%), Positives = 74/187 (39%), Gaps = 27/187 (14%)

Query: 221 ILQCCPTSDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDM 280
           +L+    + G     +  E   +K G + K   I+         S  ++K + K  G   
Sbjct: 94  LLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAG--- 150

Query: 281 SKEAARKCYEKSGLTPNDIDVIELHDCFSTNE--------LLTYEALGLCPEGQGATLVD 332
            K+ ARK  +K G      +V +     ST E        +L+ ++L L   GQ   L+ 
Sbjct: 151 GKKGARKSKKKQG------EVSKAASADSTTEGTPADGFTVLSTKSLFL---GQKLNLIH 201

Query: 333 RGDNTYGG---KWVINPSGGLISKGHPLGAT----GLAQCAELCWQLRGEAGKRQVPGAK 385
              +   G   + +INP+   I     LG T    G  +  E   +LR + G  +V GA 
Sbjct: 202 SEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAA 261

Query: 386 VALQHNL 392
           V+  H L
Sbjct: 262 VSAGHGL 268


>gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens]
          Length = 597

 Score = 30.0 bits (66), Expect = 5.7
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 1/51 (1%)

Query: 166 AGKEHMEKYGTKIEHFAKIGW-KNHKHSVNNPYSQFQDEYSLDEVMASKEV 215
           A K++ +K   K +H+  I     H+H   + YSQ Q++  + E    KEV
Sbjct: 521 AAKDYNQKLKEKFQHYPHIKRIARHRHLPKSIYSQIQEQRIMKEARRRKEV 571


>gi|20336746 H2A histone family, member Y isoform 1 [Homo sapiens]
          Length = 369

 Score = 30.0 bits (66), Expect = 5.7
 Identities = 44/186 (23%), Positives = 74/186 (39%), Gaps = 28/186 (15%)

Query: 221 ILQCCPTSDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDM 280
           +L+    + G     +  E   +K G + K   I+         S  ++K + K  G   
Sbjct: 94  LLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAG--- 150

Query: 281 SKEAARKCYEKSGLTPNDIDVIELHDCFSTNE--------LLTYEALGLCPEGQGATLVD 332
            K+ ARK  +K G      +V +     ST E        +L+ ++L L   GQ   +V 
Sbjct: 151 GKKGARKSKKKQG------EVSKAASADSTTEGTPADGFTVLSTKSLFL---GQKLQVVQ 201

Query: 333 RGDNTYGGKWVINPS------GGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKV 386
               +     V++P+      GG +  G+ L   G  +  E   +LR + G  +V GA V
Sbjct: 202 ADIASIDSDAVVHPTNTDFYIGGEV--GNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAV 259

Query: 387 ALQHNL 392
           +  H L
Sbjct: 260 SAGHGL 265


>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
           isoform 2 [Homo sapiens]
          Length = 540

 Score = 29.3 bits (64), Expect = 9.7
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)

Query: 241 FVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDID 300
           F   Y +QS  + I    M   LP S        + G    + A+RK  EKS  T  D+D
Sbjct: 170 FYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLD 229

Query: 301 VI-ELHD--CFSTNELLTYEAL 319
            + ++H+   F T    TY AL
Sbjct: 230 FLQDMHEGLYFDTE---TYNAL 248


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,619,105
Number of Sequences: 37866
Number of extensions: 925008
Number of successful extensions: 1925
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1893
Number of HSP's gapped (non-prelim): 25
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.