Search of human proteins with 19913424

Search of human proteins with 19913424

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19913424 ATPase, H+ transporting, lysosomal V1 subunit A
[Homo sapiens]
         (617 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19913424 ATPase, H+ transporting, lysosomal V1 subunit A [Hom...  1231   0.0  
gi|32189394 mitochondrial ATP synthase beta subunit precursor [H...   115   2e-25
gi|19913428 vacuolar H+ATPase B2 [Homo sapiens]                        84   5e-16
gi|19913426 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subu...    82   1e-15
gi|50345984 ATP synthase, H+ transporting, mitochondrial F1 comp...    68   2e-11
gi|4757810 ATP synthase, H+ transporting, mitochondrial F1 compl...    68   2e-11
gi|33667030 myo-inositol oxygenase [Homo sapiens]                      34   0.45 
gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]         33   0.78 
gi|110349719 titin isoform N2-A [Homo sapiens]                         31   2.9  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      31   2.9  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      31   2.9  
gi|110349715 titin isoform N2-B [Homo sapiens]                         31   2.9  
gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]            30   6.6  
gi|148539855 epidermal growth factor receptor pathway substrate ...    30   8.6  
gi|148539853 epidermal growth factor receptor pathway substrate ...    30   8.6  

>gi|19913424 ATPase, H+ transporting, lysosomal V1 subunit A [Homo
           sapiens]
          Length = 617

 Score = 1231 bits (3185), Expect = 0.0
 Identities = 617/617 (100%), Positives = 617/617 (100%)

Query: 1   MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGD 60
           MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGD
Sbjct: 1   MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGD 60

Query: 61  MATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPR 120
           MATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPR
Sbjct: 61  MATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPR 120

Query: 121 GVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHKIMLPPRNRGTVTYIA 180
           GVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHKIMLPPRNRGTVTYIA
Sbjct: 121 GVNVSALSRDIKWDFTPCKNLRVGSHITGGDIYGIVSENSLIKHKIMLPPRNRGTVTYIA 180

Query: 181 PPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPC 240
           PPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPC
Sbjct: 181 PPGNYDTSDVVLELEFEGVKEKFTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPC 240

Query: 241 VQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDG 300
           VQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDG
Sbjct: 241 VQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDG 300

Query: 301 KVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALRE 360
           KVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALRE
Sbjct: 301 KVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALRE 360

Query: 361 ISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDP 420
           ISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDP
Sbjct: 361 ISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDP 420

Query: 421 VTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAK 480
           VTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAK
Sbjct: 421 VTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAK 480

Query: 481 EILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGM 540
           EILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGM
Sbjct: 481 EILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGM 540

Query: 541 LSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSD 600
           LSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSD
Sbjct: 541 LSNMIAFYDMARRAVETTAQSDNKITWSIIREHMGDILYKLSSMKFKDPLKDGEAKIKSD 600

Query: 601 YAQLLEDMQNAFRSLED 617
           YAQLLEDMQNAFRSLED
Sbjct: 601 YAQLLEDMQNAFRSLED 617


>gi|32189394 mitochondrial ATP synthase beta subunit precursor [Homo
           sapiens]
          Length = 529

 Score =  115 bits (287), Expect = 2e-25
 Identities = 88/303 (29%), Positives = 147/303 (48%), Gaps = 26/303 (8%)

Query: 227 LLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSK---YSNSDVIIYVGCGERGNE 283
           L+TG +V+D L P  +GG   + G  G GKTV+   L      ++    ++ G GER  E
Sbjct: 183 LVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTRE 242

Query: 284 MSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDM-GY 342
            +++  +  E  +     ++    + ALV    N P  AR     TG+T++EYFRD  G 
Sbjct: 243 GNDLYHEMIESGVI---NLKDATSKVALVYGQMNEPPGARARVALTGLTVAEYFRDQEGQ 299

Query: 343 HVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREG 402
            V +  D+  R+ +A  E+S  L  +P+  GY   L   + +  ER    K       +G
Sbjct: 300 DVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITTTK-------KG 352

Query: 403 SVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMR--- 459
           S++ V A+  P  D +DP  + T   +     L + +A+   +P+V+ L S S+ M    
Sbjct: 353 SITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAELGIYPAVDPLDSTSRIMDPNI 412

Query: 460 ALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDF 519
              E+YD        +    ++ILQ+ + L +I+ ++G   L+E DK+T+  A+ I+  F
Sbjct: 413 VGSEHYD--------VARGVQKILQDYKSLQDIIAILGMDELSEEDKLTVSRARKIQ-RF 463

Query: 520 LQQ 522
           L Q
Sbjct: 464 LSQ 466



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 58  EGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSD 108
           E  + TI + + T G+  G  VL +G P+ + +GP  +G I + I  P+ +
Sbjct: 105 ESTVRTIAM-DGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDE 154


>gi|19913428 vacuolar H+ATPase B2 [Homo sapiens]
          Length = 511

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 61/222 (27%), Positives = 107/222 (48%), Gaps = 9/222 (4%)

Query: 306 MKRTALVANTSNMPVAAREASIYTGITLSEYFR-DMGYHVSMMADSTSRWAEALREISGR 364
           M    L  N +N P   R  +    +T +E+       HV ++    S +AEALRE+S  
Sbjct: 254 MDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAA 313

Query: 365 LAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSA 424
             E+P   G+P Y+   LA+ YERAGRV+      R GS++ +  ++ P  D + P+   
Sbjct: 314 REEVPGRRGFPGYMYTDLATIYERAGRVE-----GRNGSITQIPILTMPNDDITHPIPDL 368

Query: 425 TLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMR-ALDEYYDKHFTEFVPLRTKAKEIL 483
           T  I +    +D++L  R+ +P +N L S S+ M+ A+ E   +   +   +  +     
Sbjct: 369 TGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTR--KDHADVSNQLYACY 426

Query: 484 QEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGY 525
              +D+  +  +VG+ +L   D + LE  +  + +F+ Q  Y
Sbjct: 427 AIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPY 468



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 17  TFGYVHGVSGPVVTACDMAGAAMYELVRV---GHSELVGEIIRLEGDMATIQVYEETSGV 73
           T+  V GV+GP+V    +      E+V +     ++  G+++ + G  A +QV+E TSG+
Sbjct: 46  TYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGI 105

Query: 74  SVGDPVLR-TGKPLSVELGPGIMGAIFDGIQRPL 106
                    TG  L   +   ++G +F+G  +P+
Sbjct: 106 DAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPI 139


>gi|19913426 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit
           B1 [Homo sapiens]
          Length = 513

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 62/229 (27%), Positives = 109/229 (47%), Gaps = 9/229 (3%)

Query: 299 DGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFR-DMGYHVSMMADSTSRWAEA 357
           D +    M    L  N +N P   R  +    +T +E+       HV ++    S +AEA
Sbjct: 241 DFEQNGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEA 300

Query: 358 LREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDF 417
           LRE+S    E+P   G+P Y+   LA+ YERAGRV+      R GS++ +  ++ P  D 
Sbjct: 301 LREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVE-----GRGGSITQIPILTMPNDDI 355

Query: 418 SDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMR-ALDEYYDKHFTEFVPLR 476
           + P+   T  I +    +D++L  R+ +P +N L S S+ M+ A+ E   +   +   + 
Sbjct: 356 THPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTR--KDHGDVS 413

Query: 477 TKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGY 525
            +        +D+  +  +VG+ +L   D + LE  +  + +F+ Q  Y
Sbjct: 414 NQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFLQKFEKNFINQGPY 462



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 4/94 (4%)

Query: 17  TFGYVHGVSGPVVTACDMAGAAMYELVRV---GHSELVGEIIRLEGDMATIQVYEETSGV 73
           T+  V  V+GP+V    +  A   E+V       ++  G+++ + G  A +QV+E TSG+
Sbjct: 40  TYRTVCSVNGPLVVLDRVKFAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGI 99

Query: 74  SVGDPVLR-TGKPLSVELGPGIMGAIFDGIQRPL 106
                    TG  L   +   ++G +F+G  +P+
Sbjct: 100 DARKTTCEFTGDILRTPVSEDMLGRVFNGSGKPI 133


>gi|50345984 ATP synthase, H+ transporting, mitochondrial F1
           complex, alpha subunit precursor [Homo sapiens]
          Length = 553

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 61/253 (24%), Positives = 115/253 (45%), Gaps = 28/253 (11%)

Query: 217 VTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT------VISQSLSKYSNSD 270
           +  ++    P+ TG + +D+L P  +G    I G    GKT      +I+Q      + +
Sbjct: 179 IIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGSDE 238

Query: 271 ----VIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREAS 326
                 IYV  G++ + ++++++   +            MK T +V+ T++     +  +
Sbjct: 239 KKKLYCIYVAIGQKRSTVAQLVKRLTDA---------DAMKYTIVVSATASDAAPLQYLA 289

Query: 327 IYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPA---YLGARLA 383
            Y+G ++ EYFRD G H  ++ D  S+ A A R++S  L   P    YP    YL +RL 
Sbjct: 290 PYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRL- 348

Query: 384 SFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRK 443
              ERA +   + +    GS++ +  +    GD S  + +  + I      L+ +L  + 
Sbjct: 349 --LERAAK---MNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKG 403

Query: 444 HFPSVNWLISYSK 456
             P++N  +S S+
Sbjct: 404 IRPAINVGLSVSR 416


>gi|4757810 ATP synthase, H+ transporting, mitochondrial F1 complex,
           alpha subunit precursor [Homo sapiens]
          Length = 553

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 61/253 (24%), Positives = 115/253 (45%), Gaps = 28/253 (11%)

Query: 217 VTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKT------VISQSLSKYSNSD 270
           +  ++    P+ TG + +D+L P  +G    I G    GKT      +I+Q      + +
Sbjct: 179 IIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGSDE 238

Query: 271 ----VIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREAS 326
                 IYV  G++ + ++++++   +            MK T +V+ T++     +  +
Sbjct: 239 KKKLYCIYVAIGQKRSTVAQLVKRLTDA---------DAMKYTIVVSATASDAAPLQYLA 289

Query: 327 IYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPA---YLGARLA 383
            Y+G ++ EYFRD G H  ++ D  S+ A A R++S  L   P    YP    YL +RL 
Sbjct: 290 PYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRL- 348

Query: 384 SFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRK 443
              ERA +   + +    GS++ +  +    GD S  + +  + I      L+ +L  + 
Sbjct: 349 --LERAAK---MNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKG 403

Query: 444 HFPSVNWLISYSK 456
             P++N  +S S+
Sbjct: 404 IRPAINVGLSVSR 416


>gi|33667030 myo-inositol oxygenase [Homo sapiens]
          Length = 285

 Score = 33.9 bits (76), Expect = 0.45
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 401 EGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRA 460
           + SV    +      D  DP  S  LG+ Q   GLD+ L    H   +  ++ ++K+   
Sbjct: 151 QASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLDRVLMSWGHDEYMYQVMKFNKFSLP 210

Query: 461 LDEYYDKHFTEFVPLRT-KAKEILQEEEDLA 490
            + +Y   F  F P  T +  + L  ++DLA
Sbjct: 211 PEAFYMIRFHSFYPWHTGRDYQQLCSQQDLA 241


>gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
          Length = 2458

 Score = 33.1 bits (74), Expect = 0.78
 Identities = 33/124 (26%), Positives = 48/124 (38%), Gaps = 13/124 (10%)

Query: 144  GSHITGGDIYGIVSENSLIKHKIMLPPRNRGTVTYIAPPGN-YDTSDVVLELEFEGVKEK 202
            G H+  G  Y   +E  ++K  + L  + RG V YI  PG   +   VV  LE +   + 
Sbjct: 913  GGHVEAGSSY---AEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPSK- 968

Query: 203  FTMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQS 262
                    V    P T +LPA   L      L  +F  V    T +   F   + V S  
Sbjct: 969  --------VHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 1020

Query: 263  LSKY 266
            L ++
Sbjct: 1021 LKEW 1024


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 14/99 (14%)

Query: 341   GYHVSMMADSTSRWAEALR----EISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLG 396
             GYHV      + RW  A++    ++  ++  +   S Y   + A       RAG    +G
Sbjct: 20605 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE-----NRAG----IG 20655

Query: 397   NP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWG 434
              P E   SV +  A  PPG   +  VT  T     + WG
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 20694


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 14/99 (14%)

Query: 341   GYHVSMMADSTSRWAEALR----EISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLG 396
             GYHV      + RW  A++    ++  ++  +   S Y   + A       RAG    +G
Sbjct: 14300 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE-----NRAG----IG 14350

Query: 397   NP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWG 434
              P E   SV +  A  PPG   +  VT  T     + WG
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14389


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 14/99 (14%)

Query: 341   GYHVSMMADSTSRWAEALR----EISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLG 396
             GYHV      + RW  A++    ++  ++  +   S Y   + A       RAG    +G
Sbjct: 14233 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE-----NRAG----IG 14283

Query: 397   NP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWG 434
              P E   SV +  A  PPG   +  VT  T     + WG
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14322


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 14/99 (14%)

Query: 341   GYHVSMMADSTSRWAEALR----EISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLG 396
             GYHV      + RW  A++    ++  ++  +   S Y   + A       RAG    +G
Sbjct: 14108 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE-----NRAG----IG 14158

Query: 397   NP-EREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWG 434
              P E   SV +  A  PPG   +  VT  T     + WG
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14197


>gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]
          Length = 1053

 Score = 30.0 bits (66), Expect = 6.6
 Identities = 18/59 (30%), Positives = 27/59 (45%)

Query: 307 KRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRL 365
           K T+L    +N+    +E S       SE   D+G  +  +     R AEA R ++GRL
Sbjct: 372 KETSLRKEINNLRARLQEPSAQANCCDSEKNGDIGQQIKTLDQKIERVAEATRMLNGRL 430


>gi|148539855 epidermal growth factor receptor pathway substrate
           8-like protein 1 isoform b [Homo sapiens]
          Length = 596

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 21  VHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVL 80
           +H + GP+    + +G   +    V    L  + + L  D  T +  E     S+GD   
Sbjct: 219 LHFLFGPLQMIVNTSGGPEFAS-SVRRPHLTSDAVALLRDNVTPR--ENELWTSLGDSWT 275

Query: 81  RTGKPLSVELGPGIMGAIFDGIQRPLSDISSQ 112
           R G  LS E GP      F G + P++D  S+
Sbjct: 276 RPGLELSPEEGPPYRPEFFSGWEPPVTDPQSR 307


>gi|148539853 epidermal growth factor receptor pathway substrate
           8-like protein 1 isoform a [Homo sapiens]
          Length = 723

 Score = 29.6 bits (65), Expect = 8.6
 Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 21  VHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVL 80
           +H + GP+    + +G   +    V    L  + + L  D  T +  E     S+GD   
Sbjct: 346 LHFLFGPLQMIVNTSGGPEFAS-SVRRPHLTSDAVALLRDNVTPR--ENELWTSLGDSWT 402

Query: 81  RTGKPLSVELGPGIMGAIFDGIQRPLSDISSQ 112
           R G  LS E GP      F G + P++D  S+
Sbjct: 403 RPGLELSPEEGPPYRPEFFSGWEPPVTDPQSR 434


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,265,572
Number of Sequences: 37866
Number of extensions: 965918
Number of successful extensions: 2474
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2405
Number of HSP's gapped (non-prelim): 78
length of query: 617
length of database: 18,247,518
effective HSP length: 108
effective length of query: 509
effective length of database: 14,157,990
effective search space: 7206416910
effective search space used: 7206416910
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.