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Search of human proteins with 197383062
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
(521 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens] 1068 0.0
gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens] 634 0.0
gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens] 514 e-146
gi|197276620 glutamate decarboxylase 2 [Homo sapiens] 510 e-144
gi|4503875 glutamate decarboxylase 2 [Homo sapiens] 510 e-144
gi|132814448 dopa decarboxylase (aromatic L-amino acid decarboxy... 132 1e-30
gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxyla... 132 1e-30
gi|92110055 histidine decarboxylase [Homo sapiens] 130 3e-30
gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens] 64 3e-10
gi|190341074 pyridoxal-dependent decarboxylase domain containing... 59 1e-08
gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens] 42 0.001
gi|4557289 alanine-glyoxylate aminotransferase [Homo sapiens] 34 0.37
gi|39725952 angiogenic factor VG5Q [Homo sapiens] 32 1.4
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 31 3.1
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 31 3.1
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 30 4.1
gi|143771699 zinc finger protein 460 [Homo sapiens] 30 4.1
gi|115583677 sodium channel, voltage-gated, type I, alpha [Homo ... 29 9.1
gi|14150045 calcium/calmodulin-dependent protein kinase 1 alpha ... 29 9.1
gi|27437011 calcium/calmodulin-dependent protein kinase 1 alpha ... 29 9.1
>gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
Length = 521
Score = 1068 bits (2762), Expect = 0.0
Identities = 521/521 (100%), Positives = 521/521 (100%)
Query: 1 MSSDSDRQCPVDGDIDQQEMIPSKKNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEV 60
MSSDSDRQCPVDGDIDQQEMIPSKKNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEV
Sbjct: 1 MSSDSDRQCPVDGDIDQQEMIPSKKNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEV 60
Query: 61 VLKATDVNEKVCEWRPPEQLKQLLDLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFNQ 120
VLKATDVNEKVCEWRPPEQLKQLLDLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFNQ
Sbjct: 61 VLKATDVNEKVCEWRPPEQLKQLLDLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFNQ 120
Query: 121 LYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFIGWKEGDGIFNPGG 180
LYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFIGWKEGDGIFNPGG
Sbjct: 121 LYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFIGWKEGDGIFNPGG 180
Query: 181 SVSNMYAMNLARYKYCPDIKEKGLSGSPRLILFTSAECHYSMKKAASFLGIGTENVCFVE 240
SVSNMYAMNLARYKYCPDIKEKGLSGSPRLILFTSAECHYSMKKAASFLGIGTENVCFVE
Sbjct: 181 SVSNMYAMNLARYKYCPDIKEKGLSGSPRLILFTSAECHYSMKKAASFLGIGTENVCFVE 240
Query: 241 TDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADICERHSLWLHV 300
TDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADICERHSLWLHV
Sbjct: 241 TDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADICERHSLWLHV 300
Query: 301 DASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAK 360
DASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAK
Sbjct: 301 DASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAK 360
Query: 361 ASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLV 420
ASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLV
Sbjct: 361 ASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLV 420
Query: 421 DEIKKREGFKLLMEPEYANICFWYIPPSLREMEEGPEFWAKLNLVAPAIKERMMKKGSLM 480
DEIKKREGFKLLMEPEYANICFWYIPPSLREMEEGPEFWAKLNLVAPAIKERMMKKGSLM
Sbjct: 421 DEIKKREGFKLLMEPEYANICFWYIPPSLREMEEGPEFWAKLNLVAPAIKERMMKKGSLM 480
Query: 481 LGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDLLGKDM 521
LGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDLLGKDM
Sbjct: 481 LGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDLLGKDM 521
>gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]
Length = 520
Score = 634 bits (1634), Expect = 0.0
Identities = 292/497 (58%), Positives = 386/497 (77%)
Query: 25 KNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEVVLKATDVNEKVCEWRPPEQLKQLL 84
+ ++ D L D A E + ++++E + K T V++KVCEW+ PE+LKQLL
Sbjct: 24 REILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLL 83
Query: 85 DLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVY 144
DLE+R GE ++LE CR VI YSVKT HPRFFNQL++GLD ++L R +TE+LN S Y
Sbjct: 84 DLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQY 143
Query: 145 TYEVSPVFLLVEEAVLKKMIEFIGWKEGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGL 204
TYE++PVF+L+EE VL+K+ +GW GDGIF PGGS+SNMYA+NLARY+ PD K++GL
Sbjct: 144 TYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGL 203
Query: 205 SGSPRLILFTSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGA 264
P L LFTS ECHYS++K A+FLG+GT++V V+ D RGKM+PE+LE+Q+ A EGA
Sbjct: 204 RTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGA 263
Query: 265 APFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRA 324
PFLV ATSGTTVLGAFDPL+ IAD+C+RH LWLHVDA+WGGS L+S+ HR LL GI RA
Sbjct: 264 VPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRA 323
Query: 325 DSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQC 384
DSVAWNPHK+L AG+QC ALL++D S+LLK+C+ ++ASYLFQQDKFYDV+ DTGDK +QC
Sbjct: 324 DSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQC 383
Query: 385 SRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICFWY 444
RR D K W+ WKA G GLE R+++A L+RYLV+E+KKREGF+L+MEPE+ N+CFW+
Sbjct: 384 GRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWF 443
Query: 445 IPPSLREMEEGPEFWAKLNLVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSR 504
+PPSLR +E P++ +L+ VAP +KERM+K+GS+M+GYQPH + NFFR VV + ++
Sbjct: 444 VPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTC 503
Query: 505 EDMDFLLDEIDLLGKDM 521
DMDFLL+E++ LG+D+
Sbjct: 504 ADMDFLLNELERLGQDL 520
>gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]
Length = 594
Score = 514 bits (1325), Expect = e-146
Identities = 251/493 (50%), Positives = 348/493 (70%), Gaps = 17/493 (3%)
Query: 42 AKAGEKFVEEACRLIMEEV------VLKATDVNEKVCEWRPPEQLKQLLD---LEMRDSG 92
AK GE E+ + ++E V V K D + KV ++ P QL + ++ LE+ D
Sbjct: 106 AKNGE---EQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHP 162
Query: 93 EPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVF 152
E ++L CRD + Y V+T HPRFFNQL GLD L ++T N +++TYE++PVF
Sbjct: 163 ESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVF 222
Query: 153 LLVEEAVLKKMIEFIGW--KEGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGLSGSPRL 210
+L+E+ LKKM E +GW K+GDGIF+PGG++SNMY++ ARYKY P++K KG++ P+L
Sbjct: 223 VLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKL 282
Query: 211 ILFTSAECHYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVC 270
+LFTS + HYS+KKA + LG GT+NV ++ + RGK+IP + E ++ +A+++G PF V
Sbjct: 283 VLFTSEQSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAKQKGYVPFYVN 342
Query: 271 ATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWN 330
AT+GTTV GAFDP+ EIADICE+++LWLHVDA+WGG LMSRKHR L+GI RA+SV WN
Sbjct: 343 ATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWN 402
Query: 331 PHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDA 390
PHKM+ +QC A+LVK+K +L+ C A YLFQ DK YDVSYDTGDK+IQC R D
Sbjct: 403 PHKMMGVLLQCSAILVKEKG-ILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDI 461
Query: 391 FKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLM--EPEYANICFWYIPPS 448
FKFW+ WKA GT+G E ++N+ L L+ YL +IK RE F+++ EPE+ N+CFWYIP S
Sbjct: 462 FKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQS 521
Query: 449 LREMEEGPEFWAKLNLVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMD 508
LR + + P+ KL+ VAP IK MM+ G+ M+GYQP K NFFR V+ +P ++ D+D
Sbjct: 522 LRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDID 581
Query: 509 FLLDEIDLLGKDM 521
FL++EI+ LG+D+
Sbjct: 582 FLIEEIERLGQDL 594
>gi|197276620 glutamate decarboxylase 2 [Homo sapiens]
Length = 585
Score = 510 bits (1313), Expect = e-144
Identities = 238/478 (49%), Positives = 346/478 (72%), Gaps = 6/478 (1%)
Query: 48 FVEEACRLIMEEVVLKATDVNEKVCEWRPPEQLKQLLDLEMRDSGEPPHKLLELCRDVIH 107
F+++ ++++ VV K+ D + KV ++ P +L Q + E+ D + ++L C+ +
Sbjct: 110 FLQDVMNILLQYVV-KSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILMHCQTTLK 168
Query: 108 YSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFI 167
Y++KT HPR+FNQL GLD L A ++T N +++TYE++PVF+L+E LKKM E I
Sbjct: 169 YAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREII 228
Query: 168 GWK--EGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGLSGSPRLILFTSAECHYSMKKA 225
GW GDGIF+PGG++SNMYAM +AR+K P++KEKG++ PRLI FTS H+S+KK
Sbjct: 229 GWPGGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAALPRLIAFTSEHSHFSLKKG 288
Query: 226 ASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLD 285
A+ LGIGT++V ++ D RGKMIP +LE+++ +A+++G PFLV AT+GTTV GAFDPL
Sbjct: 289 AAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLL 348
Query: 286 EIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALL 345
+ADIC+++ +W+HVDA+WGG LMSRKH+ L G+ RA+SV WNPHKM+ +QC ALL
Sbjct: 349 AVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALL 408
Query: 346 VKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGL 405
V+++ L++ C ASYLFQQDK YD+SYDTGDK++QC R D FK W+ W+A GT G
Sbjct: 409 VREEG-LMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGF 467
Query: 406 EERVNRALALSRYLVDEIKKREGFKLLME--PEYANICFWYIPPSLREMEEGPEFWAKLN 463
E V++ L L+ YL + IK REG++++ + P++ N+CFWYIPPSLR +E+ E ++L+
Sbjct: 468 EAHVDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWYIPPSLRTLEDNEERMSRLS 527
Query: 464 LVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDLLGKDM 521
VAP IK RMM+ G+ M+ YQP KVNFFR V+ +P + +D+DFL++EI+ LG+D+
Sbjct: 528 KVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL 585
>gi|4503875 glutamate decarboxylase 2 [Homo sapiens]
Length = 585
Score = 510 bits (1313), Expect = e-144
Identities = 238/478 (49%), Positives = 346/478 (72%), Gaps = 6/478 (1%)
Query: 48 FVEEACRLIMEEVVLKATDVNEKVCEWRPPEQLKQLLDLEMRDSGEPPHKLLELCRDVIH 107
F+++ ++++ VV K+ D + KV ++ P +L Q + E+ D + ++L C+ +
Sbjct: 110 FLQDVMNILLQYVV-KSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILMHCQTTLK 168
Query: 108 YSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFI 167
Y++KT HPR+FNQL GLD L A ++T N +++TYE++PVF+L+E LKKM E I
Sbjct: 169 YAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREII 228
Query: 168 GWK--EGDGIFNPGGSVSNMYAMNLARYKYCPDIKEKGLSGSPRLILFTSAECHYSMKKA 225
GW GDGIF+PGG++SNMYAM +AR+K P++KEKG++ PRLI FTS H+S+KK
Sbjct: 229 GWPGGSGDGIFSPGGAISNMYAMMIARFKMFPEVKEKGMAALPRLIAFTSEHSHFSLKKG 288
Query: 226 ASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLD 285
A+ LGIGT++V ++ D RGKMIP +LE+++ +A+++G PFLV AT+GTTV GAFDPL
Sbjct: 289 AAALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLL 348
Query: 286 EIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALL 345
+ADIC+++ +W+HVDA+WGG LMSRKH+ L G+ RA+SV WNPHKM+ +QC ALL
Sbjct: 349 AVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALL 408
Query: 346 VKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGL 405
V+++ L++ C ASYLFQQDK YD+SYDTGDK++QC R D FK W+ W+A GT G
Sbjct: 409 VREEG-LMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGF 467
Query: 406 EERVNRALALSRYLVDEIKKREGFKLLME--PEYANICFWYIPPSLREMEEGPEFWAKLN 463
E V++ L L+ YL + IK REG++++ + P++ N+CFWYIPPSLR +E+ E ++L+
Sbjct: 468 EAHVDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWYIPPSLRTLEDNEERMSRLS 527
Query: 464 LVAPAIKERMMKKGSLMLGYQPHRGKVNFFRQVVISPQVSREDMDFLLDEIDLLGKDM 521
VAP IK RMM+ G+ M+ YQP KVNFFR V+ +P + +D+DFL++EI+ LG+D+
Sbjct: 528 KVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL 585
>gi|132814448 dopa decarboxylase (aromatic L-amino acid
decarboxylase) [Homo sapiens]
Length = 480
Score = 132 bits (331), Expect = 1e-30
Identities = 93/344 (27%), Positives = 163/344 (47%), Gaps = 22/344 (6%)
Query: 115 PRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAV---LKKMIE----FI 167
P FF Y +++A + A+ +++ SP +E + L KM+E F+
Sbjct: 74 PYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFL 133
Query: 168 GWK--EGDGIFNPGGSVSNMYAMNLARYKYC-------PDIKEKGLSGSPRLILFTSAEC 218
K EG G+ S + + A+ AR K P++ + + +L+ ++S +
Sbjct: 134 NEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM--EKLVAYSSDQA 191
Query: 219 HYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVL 278
H S+++A IG + + +DG M L++ + + + G PF + AT GTT
Sbjct: 192 HSSVERAGL---IGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTC 248
Query: 279 GAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAG 338
+FD L E+ IC + +WLHVDA++ GSA + + R LL+G+ ADS +NPHK L+
Sbjct: 249 CSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVN 308
Query: 339 IQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWK 398
C A+ VK ++D L + +YL + + D I RR + K W ++
Sbjct: 309 FDCSAMWVKKRTD-LTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFR 367
Query: 399 ALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICF 442
G GL+ + + + LS +++ F++ +E +CF
Sbjct: 368 MYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCF 411
>gi|4503281 dopa decarboxylase (aromatic L-amino acid decarboxylase)
[Homo sapiens]
Length = 480
Score = 132 bits (331), Expect = 1e-30
Identities = 93/344 (27%), Positives = 163/344 (47%), Gaps = 22/344 (6%)
Query: 115 PRFFNQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAV---LKKMIE----FI 167
P FF Y +++A + A+ +++ SP +E + L KM+E F+
Sbjct: 74 PYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFL 133
Query: 168 GWK--EGDGIFNPGGSVSNMYAMNLARYKYC-------PDIKEKGLSGSPRLILFTSAEC 218
K EG G+ S + + A+ AR K P++ + + +L+ ++S +
Sbjct: 134 NEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM--EKLVAYSSDQA 191
Query: 219 HYSMKKAASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVL 278
H S+++A IG + + +DG M L++ + + + G PF + AT GTT
Sbjct: 192 HSSVERAGL---IGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTC 248
Query: 279 GAFDPLDEIADICERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAG 338
+FD L E+ IC + +WLHVDA++ GSA + + R LL+G+ ADS +NPHK L+
Sbjct: 249 CSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVN 308
Query: 339 IQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWK 398
C A+ VK ++D L + +YL + + D I RR + K W ++
Sbjct: 309 FDCSAMWVKKRTD-LTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFR 367
Query: 399 ALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICF 442
G GL+ + + + LS +++ F++ +E +CF
Sbjct: 368 MYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCF 411
>gi|92110055 histidine decarboxylase [Homo sapiens]
Length = 662
Score = 130 bits (327), Expect = 3e-30
Identities = 93/320 (29%), Positives = 147/320 (45%), Gaps = 25/320 (7%)
Query: 129 SLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKKMIEFIGWKE----------GDGIFNP 178
SL+ + +A+N +T+ SP +E V+ + + +G E G G+
Sbjct: 89 SLLGDMLADAINCLGFTWASSPACTELEMNVMDWLAKMLGLPEHFLHHHPSSQGGGVLQS 148
Query: 179 GGSVSNMYAMNLARYKYC-------PDIKEKGLSGSPRLILFTSAECHYSMKKAASFLGI 231
S S + A+ AR PD E L+ RL+ + S + H S++KA I
Sbjct: 149 TVSESTLIALLAARKNKILEMKTSEPDADESCLNA--RLVAYASDQAHSSVEKAGL---I 203
Query: 232 GTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADIC 291
+ F+ D + E L+K + + ++ G P VCAT GTT + AFD L E+ IC
Sbjct: 204 SLVKMKFLPVDDNFSLRGEALQKAIEEDKQRGLVPVFVCATLGTTGVCAFDCLSELGPIC 263
Query: 292 ERHSLWLHVDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSD 351
R LWLH+DA++ G+A + + R L GI ADS +NP K +M C VKDK
Sbjct: 264 AREGLWLHIDAAYAGTAFLCPEFRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYK 323
Query: 352 LLKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNR 411
L++ +S YL + V+ D I SRR + K W ++ G L+ V
Sbjct: 324 -LQQTFSVNPIYLRHANS--GVATDFMHWQIPLSRRFRSVKLWFVIRSFGVKNLQAHVRH 380
Query: 412 ALALSRYLVDEIKKREGFKL 431
+++Y ++ F++
Sbjct: 381 GTEMAKYFESLVRNDPSFEI 400
>gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens]
Length = 224
Score = 64.3 bits (155), Expect = 3e-10
Identities = 40/111 (36%), Positives = 59/111 (53%), Gaps = 12/111 (10%)
Query: 42 AKAGEKFVEEACRLIMEEV------VLKATDVNEKVCEWRPPEQLKQLLD---LEMRDSG 92
AK GE E+ + ++E V V K D + KV ++ P QL + ++ LE+ D
Sbjct: 106 AKNGE---EQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHP 162
Query: 93 EPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSV 143
E ++L CRD + Y V+T HPRFFNQL GLD L ++T N ++
Sbjct: 163 ESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM 213
>gi|190341074 pyridoxal-dependent decarboxylase domain containing 1
[Homo sapiens]
Length = 788
Score = 58.5 bits (140), Expect = 1e-08
Identities = 45/188 (23%), Positives = 79/188 (42%), Gaps = 21/188 (11%)
Query: 252 LEKQVWQARKEGAAPFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVDASWGGSALMS 311
LEK + + G P L+ A +GT +G D + + ++CE++ +WLHV+
Sbjct: 221 LEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVE---------- 270
Query: 312 RKHRKLLHGIHRADSVAWNPHKMLMAGIQCCALLVKDKSDLLKKCYSAKASYLFQQDKFY 371
G++ A ++A +C ++ + L A Y
Sbjct: 271 --------GVNLATLALGYVSSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALT 322
Query: 372 DVSYDTGDKSIQCSRRPDAFKFWMTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKL 431
V+ T +K R A W++ + LG G ER+ A LS+ L + +KK K+
Sbjct: 323 LVAGLTSNKPTDKLR---ALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKI 379
Query: 432 LMEPEYAN 439
L+E E ++
Sbjct: 380 LVEDELSS 387
>gi|31982936 sphingosine-1-phosphate lyase 1 [Homo sapiens]
Length = 568
Score = 42.0 bits (97), Expect = 0.001
Identities = 68/286 (23%), Positives = 110/286 (38%), Gaps = 41/286 (14%)
Query: 166 FIGWKEGDGIFNPGGSVSNMYAMNLARYKYCPDIK-EKGLSGSPRLILFTSAECHYSMKK 224
F G + G GG+ S + A R D+ EKG+ +P ++ SA H + K
Sbjct: 196 FNGGPDSCGCVTSGGTESILMACKAYR-----DLAFEKGIK-TPEIVAPQSA--HAAFNK 247
Query: 225 AASFLGIGTENVCFVETDGRGKMIPEELEKQVWQARKEGAAPFLVCATSGTTVLGAFDPL 284
AAS+ G+ V KM+ E++ + + LVC+T G DP+
Sbjct: 248 AASYFGMKIVRVPLT------KMM--EVDVRAMRRAISRNTAMLVCSTPQFPH-GVIDPV 298
Query: 285 DEIADICERHSLWLHVDASWGGSAL--MSRKHRKLLH----GIHRADSVAWNPHKMLMAG 338
E+A + ++ + LHVDA GG + M + L H + S++ + HK A
Sbjct: 299 PEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAP 358
Query: 339 IQCCALLVKDKSDLLKKCYSAKASYLFQQDKFYDVSYDTG--DKSIQCSRRPDAFK--FW 394
+L DK +Y F F D + G RP W
Sbjct: 359 KGSSLVLYSDKK---------YRNYQF----FVDTDWQGGIYASPTIAGSRPGGISAACW 405
Query: 395 MTWKALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANI 440
G G E + + +R+L E++ +G + P+ + I
Sbjct: 406 AALMHFGENGYVEATKQIIKTARFLKSELENIKGIFVFGNPQLSVI 451
>gi|4557289 alanine-glyoxylate aminotransferase [Homo sapiens]
Length = 392
Score = 33.9 bits (76), Expect = 0.37
Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 6/68 (8%)
Query: 258 QARKEGAA---PFLVCATSGTTVLGAFDPLDEIADICERHSLWLHVD--ASWGGSAL-MS 311
Q +EG A P L+ T G + G PLD ++C R+ L VD AS GG+ L M
Sbjct: 137 QEVEEGLAQHKPVLLFLTHGESSTGVLQPLDGFGELCHRYKCLLLVDSVASLGGTPLYMD 196
Query: 312 RKHRKLLH 319
R+ +L+
Sbjct: 197 RQGIDILY 204
>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
Length = 714
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/32 (37%), Positives = 20/32 (62%)
Query: 161 KKMIEFIGWKEGDGIFNPGGSVSNMYAMNLAR 192
+KM+E +GWK+G+G+ GG + + L R
Sbjct: 624 RKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRR 655
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 30.8 bits (68), Expect = 3.1
Identities = 14/44 (31%), Positives = 24/44 (54%)
Query: 119 NQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKK 162
+ LY G+D+Y+ + R E LN ++ + PV + +A L K
Sbjct: 285 DSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDK 328
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 30.8 bits (68), Expect = 3.1
Identities = 14/44 (31%), Positives = 24/44 (54%)
Query: 119 NQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKK 162
+ LY G+D+Y+ + R E LN ++ + PV + +A L K
Sbjct: 285 DSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDK 328
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 30.4 bits (67), Expect = 4.1
Identities = 14/44 (31%), Positives = 24/44 (54%)
Query: 119 NQLYAGLDYYSLVARFMTEALNPSVYTYEVSPVFLLVEEAVLKK 162
+ LY G+D+Y+ + R E LN ++ + PV + +A L K
Sbjct: 288 DSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDK 331
>gi|143771699 zinc finger protein 460 [Homo sapiens]
Length = 562
Score = 30.4 bits (67), Expect = 4.1
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 20/97 (20%)
Query: 37 GPTTDAKAGE-----KFVE---EACRLIMEEVVLKATDVNEKVCEWRPPE------QLKQ 82
GP TD+ E KF E E C L+ E +L +V + PE + K
Sbjct: 157 GPVTDSLIHEGENSYKFEEMFNENCFLVQHEQILP------RVKPYDCPECGKAFGKSKH 210
Query: 83 LLDLEMRDSGEPPHKLLELCRDVIHYSVKTNHPRFFN 119
LL + +GE P+K LE +D S T H R N
Sbjct: 211 LLQHHIIHTGEKPYKCLECGKDFNRRSHLTRHQRTHN 247
>gi|115583677 sodium channel, voltage-gated, type I, alpha [Homo
sapiens]
Length = 1998
Score = 29.3 bits (64), Expect = 9.1
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 234 ENVCFVETDGRGKMIPEELE--------KQVWQARKEGAAPFLVCATSGTTVLGAFDPLD 285
+N+ F+ D +M+ E LE K+ + +G A F ATS +L F+PL
Sbjct: 59 KNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLR 118
Query: 286 EIADICERHSLW 297
+IA HSL+
Sbjct: 119 KIAIKILVHSLF 130
>gi|14150045 calcium/calmodulin-dependent protein kinase 1 alpha
isoform a [Homo sapiens]
Length = 505
Score = 29.3 bits (64), Expect = 9.1
Identities = 13/41 (31%), Positives = 22/41 (53%)
Query: 22 PSKKNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEVVL 62
P++ N LV ++ GP + + F EE RL + +V+L
Sbjct: 221 PAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVIL 261
>gi|27437011 calcium/calmodulin-dependent protein kinase 1 alpha
isoform a [Homo sapiens]
Length = 505
Score = 29.3 bits (64), Expect = 9.1
Identities = 13/41 (31%), Positives = 22/41 (53%)
Query: 22 PSKKNAVLVDGVVLNGPTTDAKAGEKFVEEACRLIMEEVVL 62
P++ N LV ++ GP + + F EE RL + +V+L
Sbjct: 221 PAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVIL 261
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,723,439
Number of Sequences: 37866
Number of extensions: 949020
Number of successful extensions: 2086
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2052
Number of HSP's gapped (non-prelim): 22
length of query: 521
length of database: 18,247,518
effective HSP length: 107
effective length of query: 414
effective length of database: 14,195,856
effective search space: 5877084384
effective search space used: 5877084384
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.