Search of human proteins with 196049380

Search of human proteins with 196049380

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|196049380 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
isoform 2 [Homo sapiens]
         (835 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|196049380 3-hydroxy-3-methylglutaryl-Coenzyme A reductase iso...  1646   0.0  
gi|4557643 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isofo...  1621   0.0  
gi|66932902 SREBF chaperone protein [Homo sapiens]                     70   6e-12
gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]      49   2e-05
gi|148277106 hypothetical protein LOC442213 [Homo sapiens]             48   3e-05
gi|194018513 patched domain containing 3 [Homo sapiens]                43   0.001
gi|148271104 patched domain containing 1 [Homo sapiens]                42   0.003
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    33   1.4  
gi|130502162 RAS protein activator like 3 [Homo sapiens]               31   4.2  
gi|15277417 capping protein alpha 3 [Homo sapiens]                     31   4.2  
gi|66773344 hypothetical protein LOC140710 [Homo sapiens]              30   7.1  
gi|157364937 OTU domain containing 6B [Homo sapiens]                   30   9.3  

>gi|196049380 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
           isoform 2 [Homo sapiens]
          Length = 835

 Score = 1646 bits (4262), Expect = 0.0
 Identities = 835/835 (100%), Positives = 835/835 (100%)

Query: 1   MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS 60
           MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS
Sbjct: 1   MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS 60

Query: 61  DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG 120
           DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
Sbjct: 61  DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG 120

Query: 121 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG 180
           LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
Sbjct: 121 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG 180

Query: 181 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR 240
           VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
Sbjct: 181 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR 240

Query: 241 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR 300
           VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR
Sbjct: 241 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR 300

Query: 301 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT 360
           IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT
Sbjct: 301 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT 360

Query: 361 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS 420
           QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS
Sbjct: 361 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS 420

Query: 421 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK 480
           SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK
Sbjct: 421 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK 480

Query: 481 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLLGGGASSRVLADGMTRGPV 540
           LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLLGGGASSRVLADGMTRGPV
Sbjct: 481 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLLGGGASSRVLADGMTRGPV 540

Query: 541 VRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGD 600
           VRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGD
Sbjct: 541 VRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGD 600

Query: 601 AMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIP 660
           AMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIP
Sbjct: 601 AMGMNMISKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIP 660

Query: 661 AKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVG 720
           AKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVG
Sbjct: 661 AKVVREVLKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVG 720

Query: 721 SSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGE 780
           SSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGE
Sbjct: 721 SSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGE 780

Query: 781 NARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA 835
           NARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
Sbjct: 781 NARQLARIVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA 835


>gi|4557643 3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform
           1 [Homo sapiens]
          Length = 888

 Score = 1621 bits (4198), Expect = 0.0
 Identities = 835/888 (94%), Positives = 835/888 (94%), Gaps = 53/888 (5%)

Query: 1   MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS 60
           MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS
Sbjct: 1   MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS 60

Query: 61  DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG 120
           DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
Sbjct: 61  DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG 120

Query: 121 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG 180
           LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
Sbjct: 121 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG 180

Query: 181 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR 240
           VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
Sbjct: 181 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR 240

Query: 241 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR 300
           VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR
Sbjct: 241 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR 300

Query: 301 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT 360
           IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT
Sbjct: 301 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT 360

Query: 361 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS 420
           QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS
Sbjct: 361 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS 420

Query: 421 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK 480
           SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK
Sbjct: 421 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK 480

Query: 481 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSL------------------- 521
           LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSL                   
Sbjct: 481 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV 540

Query: 522 ----------------------------------LGGGASSRVLADGMTRGPVVRLPRAC 547
                                             LGGGASSRVLADGMTRGPVVRLPRAC
Sbjct: 541 AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC 600

Query: 548 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI 607
           DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI
Sbjct: 601 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI 660

Query: 608 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV 667
           SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV
Sbjct: 661 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV 720

Query: 668 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL 727
           LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL
Sbjct: 721 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL 780

Query: 728 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR 787
           MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR
Sbjct: 781 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR 840

Query: 788 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA 835
           IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
Sbjct: 841 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA 888


>gi|66932902 SREBF chaperone protein [Homo sapiens]
          Length = 1279

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 54/226 (23%), Positives = 108/226 (47%), Gaps = 15/226 (6%)

Query: 53  FEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFST--VV 110
           F+E++  +++I L  T  I   YIYF  + +  + SK+ L +A + T+ SS + S     
Sbjct: 276 FKEEIGVAELIPLVTTYIILFAYIYFSTRKIDMVKSKWGLALAAVVTVLSSLLMSVGLCT 335

Query: 111 IHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTL 170
           +  L   L G  E  P+ +++I L     L K  +S+    EV+  IA+G++    +   
Sbjct: 336 LFGLTPTLNG-GEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSSESWSIMK 394

Query: 171 DALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSL---VLELSRESR 227
           +   E  +I +G  + V  ++  C F  + +++++F+ M FF   +S+    +EL+  ++
Sbjct: 395 NMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMLFFTTVLSIDIRRMELADLNK 454

Query: 228 ---------EGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGL 264
                      +P+ Q + + R L    + P+ +T +     +L L
Sbjct: 455 RLPPEACLPSAKPVGQPTRYERQLAVRPSTPHTITLQPSSFRNLRL 500


>gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]
          Length = 1278

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 39/176 (22%), Positives = 81/176 (46%), Gaps = 8/176 (4%)

Query: 60  SDIIILTITRCIAILYIYFQFQNLRQ-----LGSKYILGIAGLFTIFSSFVFSTVVIHFL 114
           SD+  + I+  I  LYI     +++      + SK  LGIAG+  + SS   S  V  ++
Sbjct: 619 SDVFTVVISYAIMFLYISLALGHIKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYI 678

Query: 115 DKELTGL-NEALPFFLLLIDLSRASTLAK-FALSSNSQDE-VRENIARGMAILGPTFTLD 171
              LT +  E +PF +L + +     L + +      Q E + + + R +  + P+  L 
Sbjct: 679 GLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLS 738

Query: 172 ALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESR 227
           +  E +   +G +S +  +     F  ++V  ++ + +T F + + L ++   ++R
Sbjct: 739 SFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNR 794


>gi|148277106 hypothetical protein LOC442213 [Homo sapiens]
          Length = 829

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 34/164 (20%), Positives = 68/164 (41%), Gaps = 16/164 (9%)

Query: 86  LGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFAL 145
           L SK  LG+ G+ T+  S + +  +    D +       +PFF +         L     
Sbjct: 241 LRSKPFLGLLGVLTVCISIITAAGIFFITDGKYNSTLLGIPFFAMGHGTKGVFELLSGWR 300

Query: 146 SSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGT--MSGVRQLEIMCCFGCMSVLA 203
            +      ++ IA   + +  T+T+ + +  +  G+G    + +  +++ C   C+S+L 
Sbjct: 301 RTKENLPFKDRIADAYSDVMVTYTMTSSLYFITFGMGASPFTNIEAVKVFCQNMCVSILL 360

Query: 204 NYFVFMTFFPACVSLVLEL--------------SRESREGRPIW 233
           NYF   +FF +C+    +L              S E  + +P+W
Sbjct: 361 NYFYIFSFFGSCLVFAGQLEQNRYHSIFCCKIPSAEYLDRKPVW 404


>gi|194018513 patched domain containing 3 [Homo sapiens]
          Length = 767

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 33/157 (21%), Positives = 68/157 (43%), Gaps = 10/157 (6%)

Query: 62  IIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGL 121
           II+  +T C       F+F  +R   +K  +   G+ + F + V    ++  +      +
Sbjct: 394 IILFAVTSC-------FRFDCIR---NKMCVAAFGVISAFLAVVSGFGLLLHIGVPFVII 443

Query: 122 NEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGV 181
               PF +L + +     +      +N  D++RE ++   +    + T+  +   L +  
Sbjct: 444 VANSPFLILGVGVDDMFIMISAWHKTNLADDIRERMSNVYSKAAVSITITTITNILALYT 503

Query: 182 GTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSL 218
           G MS  R ++  C +  M++L  YF  +T F A ++L
Sbjct: 504 GIMSSFRSVQCFCIYTGMTLLFCYFYNITCFGAFMAL 540


>gi|148271104 patched domain containing 1 [Homo sapiens]
          Length = 888

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 35/180 (19%), Positives = 73/180 (40%), Gaps = 9/180 (5%)

Query: 40  NNKICGWNYECPKFEEDV-----LSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGI 94
           N+K+  + Y      ED      +S   ++ ++   + +  +    Q+   + SK  LG+
Sbjct: 244 NSKVKMYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDC--VRSKPWLGL 301

Query: 95  AGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASTLAKFALSSNSQDEVR 154
            GL TI  + + +  +I+    +       +PF +L   L     +      +     V+
Sbjct: 302 LGLVTISLATLTAAGIINLTGGKYNSTFLGVPFVMLGHGLYGTFEMLSSWRKTREDQHVK 361

Query: 155 ENIARGMAILGPTFTLDALVECLVIGVGT--MSGVRQLEIMCCFGCMSVLANYFVFMTFF 212
           E  A   A    +F+L   +  +  G+G    + +    I CC  C+++  NY   ++F+
Sbjct: 362 ERTAAVYADSMLSFSLTTAMYLVTFGIGASPFTNIEAARIFCCNSCIAIFFNYLYVLSFY 421


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 32.7 bits (73), Expect = 1.4
 Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 4/64 (6%)

Query: 324  ITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVTQKKVP--DNCCRREPMLVRNNQK 381
            +T S  L   V+  FF   + +  + L   + + + TQ+ +P  DN C REP    N  K
Sbjct: 1260 VTFSALLPGGVRGQFFPSEDLQEQIYLNRTLLTTISTQRVLPFDDNICLREP--CENYMK 1317

Query: 382  CDSV 385
            C SV
Sbjct: 1318 CVSV 1321


>gi|130502162 RAS protein activator like 3 [Homo sapiens]
          Length = 1011

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 386 EEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIELPREPR 443
           +E   +  E ++E   P + E  TPN   + +G  +LLD   VL+  E   E PR PR
Sbjct: 106 QEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGGEE--EGPRRPR 161


>gi|15277417 capping protein alpha 3 [Homo sapiens]
          Length = 299

 Score = 31.2 bits (69), Expect = 4.2
 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 5/52 (9%)

Query: 201 VLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSH----FARVLEEEENK 248
           V    FV   FF  CV+L +E+S++ +E   I   +     FAR++EE+ENK
Sbjct: 185 VTGRIFVQAHFF-RCVNLHIEISKDLKESLEIVNQAQLALSFARLVEEQENK 235


>gi|66773344 hypothetical protein LOC140710 [Homo sapiens]
          Length = 1016

 Score = 30.4 bits (67), Expect = 7.1
 Identities = 28/127 (22%), Positives = 55/127 (43%), Gaps = 6/127 (4%)

Query: 375 LVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEP 434
           L+R  ++   V ++  +   +++EV++   A  +  N          L++T       + 
Sbjct: 57  LIRGLEQDVKVSKDISMRLHKELEVVEKKRARLEEENEEL----RQRLIETELAKQVLQT 112

Query: 435 EIELPREPRPNEECLQILGNAEKGAKFLSDAEII--QLVNAKHIPAYKLETLMETHERGV 492
           E+E PRE    +   + LG A+K      D+  +  QL  AK   A   + L +  +   
Sbjct: 113 ELERPREHSLKKRGTRSLGKADKKTLVQEDSADLKCQLHFAKEESALMCKKLTKLAKEND 172

Query: 493 SIRRQLL 499
           S++ +LL
Sbjct: 173 SMKEELL 179


>gi|157364937 OTU domain containing 6B [Homo sapiens]
          Length = 323

 Score = 30.0 bits (66), Expect = 9.3
 Identities = 44/195 (22%), Positives = 78/195 (40%), Gaps = 30/195 (15%)

Query: 328 LALLLAVKYIFFEQTETESTL-----SLKNPITSPVVTQKK-VPDNCCRREPMLVRNNQK 381
           L  L+ ++ +  E+ + E  L       K  + + +   K  VP N  +R   L  +  K
Sbjct: 25  LGYLVVMEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAK 84

Query: 382 CDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNSSLLDTSSVLVTQEPEIELPRE 441
              +E+E       ++E +K    E    N+   V  N S L    VL  Q P I   ++
Sbjct: 85  ---LEKEMEQKHREELEQLKLTTKE----NKIDSVAVNISNL----VLENQPPRISKAQK 133

Query: 442 PRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSK 501
            R  +  L+     ++  + +++AEI  L  A+H+ + KL  ++          RQL  K
Sbjct: 134 RREKKAALE-----KEREERIAEAEIENLTGARHMESEKLAQILAA--------RQLEIK 180

Query: 502 KLSEPSSLQYLPYRD 516
           ++       Y    D
Sbjct: 181 QIPSDGHCMYKAIED 195


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,750,862
Number of Sequences: 37866
Number of extensions: 1211163
Number of successful extensions: 2952
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2940
Number of HSP's gapped (non-prelim): 17
length of query: 835
length of database: 18,247,518
effective HSP length: 111
effective length of query: 724
effective length of database: 14,044,392
effective search space: 10168139808
effective search space used: 10168139808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.