Guide to the Human Genome
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Search of human proteins with 195972892

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195972892 fatty acid amide hydrolase 2 [Homo sapiens]
         (532 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195972892 fatty acid amide hydrolase 2 [Homo sapiens]             1078   0.0  
gi|166795287 fatty acid amide hydrolase [Homo sapiens]                122   8e-28
gi|222831590 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-li...    89   1e-17
gi|18105054 kinesin-associated protein 3 [Homo sapiens]                32   1.4  
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]      31   3.2  
gi|188219571 putative homeodomain transcription factor 2 isoform...    30   7.2  
gi|188219569 putative homeodomain transcription factor 2 isoform...    30   7.2  
gi|188219565 putative homeodomain transcription factor 2 isoform...    30   7.2  
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]               29   9.4  
gi|205360989 hypothetical protein LOC205327 [Homo sapiens]             29   9.4  
gi|5802998 Cdc42 effector protein 2 [Homo sapiens]                     29   9.4  
gi|91754185 hypothetical protein LOC254268 [Homo sapiens]              29   9.4  

>gi|195972892 fatty acid amide hydrolase 2 [Homo sapiens]
          Length = 532

 Score = 1078 bits (2788), Expect = 0.0
 Identities = 532/532 (100%), Positives = 532/532 (100%)

Query: 1   MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLI 60
           MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLI
Sbjct: 1   MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLI 60

Query: 61  RQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENK 120
           RQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENK
Sbjct: 61  RQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENK 120

Query: 121 WPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELC 180
           WPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELC
Sbjct: 121 WPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELC 180

Query: 181 MWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGI 240
           MWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGI
Sbjct: 181 MWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGI 240

Query: 241 FGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKV 300
           FGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKV
Sbjct: 241 FGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKV 300

Query: 301 HLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLW 360
           HLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLW
Sbjct: 301 HLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLW 360

Query: 361 IAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRY 420
           IAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRY
Sbjct: 361 IAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRY 420

Query: 421 SNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSAL 480
           SNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSAL
Sbjct: 421 SNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSAL 480

Query: 481 GLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF 532
           GLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF
Sbjct: 481 GLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF 532


>gi|166795287 fatty acid amide hydrolase [Homo sapiens]
          Length = 579

 Score =  122 bits (306), Expect = 8e-28
 Identities = 81/260 (31%), Positives = 127/260 (48%), Gaps = 15/260 (5%)

Query: 35  KFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFE 94
           +F  + P   +E LL L   QL + +  R++    V+  Y+ +  +VN   N +  Y   
Sbjct: 61  RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSY--- 117

Query: 95  EAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAK 154
                       LA+ +   +    +    GVP+++KE F  +G  ++ GL       A+
Sbjct: 118 ------------LADCETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAE 165

Query: 155 TDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTL 214
            D+ VV +LK  GA+P   TN  +    Y+ SN ++G++ NP+      GGSSGGEG  +
Sbjct: 166 CDSVVVHVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALI 225

Query: 215 AAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCR 274
            +  S +G+G+DIGGSIR P+ F GI G KP+   +   G      G + + L  GPM R
Sbjct: 226 GSGGSPLGLGTDIGGSIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMAR 285

Query: 275 YAEDLAPMLKVMAGPGIKRL 294
             E LA  L+ +    + RL
Sbjct: 286 DVESLALCLRALLCEDMFRL 305


>gi|222831590 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like
           1 [Homo sapiens]
          Length = 528

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 71/255 (27%), Positives = 116/255 (45%), Gaps = 32/255 (12%)

Query: 55  QLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDE 114
           +++  ++Q ++   ++ Q  ++ IK     +N  +    E A+K+A   +++    Q   
Sbjct: 8   EVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQ--- 63

Query: 115 ATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGIT 174
               +     G+P+ VK+ F   G+  +      +  I   +ATVV  L   GA+ +G T
Sbjct: 64  ----SLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKT 119

Query: 175 NCSELCMWYESSNKIYGRSNNP--YDLQH------------------IVGGSSGGEGCTL 214
           N  E  M   S++ ++G   NP  Y  Q+                  I GGSSGG    +
Sbjct: 120 NLDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAV 179

Query: 215 AAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCR 274
           +A      +GSD GGS R PA   G+ G KPS G+V   G  PL V + ++    G + R
Sbjct: 180 SAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPL-VNSMDV---PGILTR 235

Query: 275 YAEDLAPMLKVMAGP 289
             +D A +L  +AGP
Sbjct: 236 CVDDAAIVLGALAGP 250



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 18/49 (36%), Positives = 28/49 (57%)

Query: 473 YTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEK 521
           +T   +  GLP    P+ L+ +GLP+G+Q +   F D   L VA++ EK
Sbjct: 448 FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496


>gi|18105054 kinesin-associated protein 3 [Homo sapiens]
          Length = 792

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 6/109 (5%)

Query: 342 GASVQHVKLKKMKYSFQLWIAMM-SAKGHDGKEPVKFVDLLGDHGKHVS--PLWELIKWC 398
           G  ++ +  + +K+   L + M+ +   HDG     F+D +GD    +S     E +  C
Sbjct: 465 GNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAAQISNDEEEEFVIEC 524

Query: 399 LG-LSVYTIPSIG--LALLEEKLRYSNEKYQKFKAVEESLRKELVDMLG 444
           LG L+  TIP +   L L E KL    +   K  A E+ L  E+V M+G
Sbjct: 525 LGTLANLTIPDLDWELVLKEYKLVPYLKDKLKPGAAEDDLVLEVVIMIG 573


>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
          Length = 822

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 276 AEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVV 335
           AE L  MLK +A   ++  ++        L+      +       K D  L+++QK+ + 
Sbjct: 302 AESLQVMLKTLAEELMQTQQMLLNKEEAVLELEKRIEESSETCEKKSDIVLLLSQKQALE 361

Query: 336 HLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVD 379
            L+     SVQ ++  + K+S Q  +     + +DGKEP   V+
Sbjct: 362 ELKQ----SVQQLRCTEAKFSAQKELLEQKVQENDGKEPPPVVN 401


>gi|188219571 putative homeodomain transcription factor 2 isoform 2
           [Homo sapiens]
          Length = 747

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 26/102 (25%)

Query: 343 ASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHG---------------KH 387
           + V H +LKK++ + ++W+++ S     G  P + VD++                    H
Sbjct: 562 SEVPHFRLKKVQ-NIKMWLSLRSYLKRRG--PQRSVDVIVSSAFLLTISVVFICCAQLLH 618

Query: 388 VSPL-------WELIKWCLGLSVYTIPSIGLALLEEKLRYSN 422
           V  +       WEL+ WC+ L+++ +  + L   E   +YSN
Sbjct: 619 VHEIFLDCHYNWELVIWCISLTLFLLRFVTLG-SETSKKYSN 659


>gi|188219569 putative homeodomain transcription factor 2 isoform 1
           [Homo sapiens]
          Length = 751

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 26/102 (25%)

Query: 343 ASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHG---------------KH 387
           + V H +LKK++ + ++W+++ S     G  P + VD++                    H
Sbjct: 566 SEVPHFRLKKVQ-NIKMWLSLRSYLKRRG--PQRSVDVIVSSAFLLTISVVFICCAQLLH 622

Query: 388 VSPL-------WELIKWCLGLSVYTIPSIGLALLEEKLRYSN 422
           V  +       WEL+ WC+ L+++ +  + L   E   +YSN
Sbjct: 623 VHEIFLDCHYNWELVIWCISLTLFLLRFVTLG-SETSKKYSN 663


>gi|188219565 putative homeodomain transcription factor 2 isoform 2
           [Homo sapiens]
          Length = 747

 Score = 29.6 bits (65), Expect = 7.2
 Identities = 24/102 (23%), Positives = 46/102 (45%), Gaps = 26/102 (25%)

Query: 343 ASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHG---------------KH 387
           + V H +LKK++ + ++W+++ S     G  P + VD++                    H
Sbjct: 562 SEVPHFRLKKVQ-NIKMWLSLRSYLKRRG--PQRSVDVIVSSAFLLTISVVFICCAQLLH 618

Query: 388 VSPL-------WELIKWCLGLSVYTIPSIGLALLEEKLRYSN 422
           V  +       WEL+ WC+ L+++ +  + L   E   +YSN
Sbjct: 619 VHEIFLDCHYNWELVIWCISLTLFLLRFVTLG-SETSKKYSN 659


>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
          Length = 1910

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 16/43 (37%), Positives = 18/43 (41%)

Query: 112 EDEATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAK 154
           +D  T ENK P L VP        + G P S  L   R   AK
Sbjct: 811 DDSMTQENKSPLLSVPFLSSARRSVSGSPESDELQELRTRSAK 853


>gi|205360989 hypothetical protein LOC205327 [Homo sapiens]
          Length = 385

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 24/105 (22%)

Query: 291 IKRLKLDTKVH--LKDLK-FYWME--HDGGSFLMSKVDQDLI-MTQKKVVVHLETILGAS 344
           +K  K D  +   +K ++  YW++  H GGS       + L    Q  ++VH        
Sbjct: 277 LKEAKKDKNIDAFIKSIRTMYWLDGGHSGGSNTWVTYPEVLKEFAQTGIIVHT------- 329

Query: 345 VQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHGKHVS 389
             HV   +++   + WI         GKE  KFV +LGD G  V+
Sbjct: 330 --HVTPYQVRDPMRSWI---------GKEHKKFVQILGDLGMQVT 363


>gi|5802998 Cdc42 effector protein 2 [Homo sapiens]
          Length = 210

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 29/82 (35%), Positives = 31/82 (37%), Gaps = 11/82 (13%)

Query: 441 DMLGD----DGVF-LYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKG 495
           DM GD     G F L P      P+       PF F  T       LP    PL  NA  
Sbjct: 50  DMFGDISFLQGKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAIS 109

Query: 496 LPLGIQVVAGPFNDHLTLAVAQ 517
           LP    V+ GP    LTL  AQ
Sbjct: 110 LP----VIGGP--QALTLPTAQ 125


>gi|91754185 hypothetical protein LOC254268 [Homo sapiens]
          Length = 836

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 8/77 (10%)

Query: 272 MCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDG------GSFLMSKVDQD 325
           MC+  ++    LK       KR+K D+  HL+D K    +  G       +FL +K D+ 
Sbjct: 380 MCQKLKEQTDQLKTKVQEFSKRIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATK-DKH 438

Query: 326 LIMTQKKVVVHLETILG 342
           L + Q++V  H  TI+G
Sbjct: 439 LTL-QQQVHKHESTIVG 454


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,682,703
Number of Sequences: 37866
Number of extensions: 977756
Number of successful extensions: 2301
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2291
Number of HSP's gapped (non-prelim): 17
length of query: 532
length of database: 18,247,518
effective HSP length: 107
effective length of query: 425
effective length of database: 14,195,856
effective search space: 6033238800
effective search space used: 6033238800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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