Search of human proteins with 19557664

Search of human proteins with 19557664

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19557664 osteoclast-associated receptor isoform 5 [Homo
sapiens]
         (252 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens]   521   e-148
gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens]   510   e-145
gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens]   509   e-144
gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens]   423   e-119
gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo...   144   1e-34
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (...   122   2e-28
gi|208879429 hypothetical LOC441864 [Homo sapiens]                    122   3e-28
gi|32895363 leukocyte immunoglobulin-like receptor subfamily A m...   118   6e-27
gi|32490553 leukocyte immunoglobulin-like receptor subfamily A m...   118   6e-27
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A...   117   1e-26
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A...   107   1e-23
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m...   105   5e-23
gi|46488946 killer cell immunoglobulin-like receptor, three doma...   104   6e-23
gi|134268642 killer cell immunoglobulin-like receptor, three dom...    98   6e-21
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (...    98   8e-21
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B...    97   1e-20
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B...    97   1e-20
gi|66267727 killer cell immunoglobulin-like receptor, two domain...    96   3e-20
gi|11968154 killer cell immunoglobulin-like receptor, two domain...    96   4e-20
gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B...    93   3e-19
gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B...    93   3e-19
gi|124107604 killer cell immunoglobulin-like receptor, two domai...    93   3e-19
gi|124107606 killer cell immunoglobulin-like receptor, two domai...    93   3e-19
gi|124107610 killer cell immunoglobulin-like receptor, two domai...    93   3e-19
gi|143770741 glycoprotein VI (platelet) isoform 1 [Homo sapiens]       92   3e-19
gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens]       92   3e-19
gi|32895365 leukocyte immunoglobulin-like receptor subfamily A m...    91   1e-18
gi|32895361 leukocyte immunoglobulin-like receptor subfamily A m...    91   1e-18
gi|62632748 killer-cell Ig-like receptor [Homo sapiens]                91   1e-18
gi|19743861 Fc alpha receptor isoform d [Homo sapiens]                 91   1e-18

>gi|19557664 osteoclast-associated receptor isoform 5 [Homo sapiens]
          Length = 252

 Score =  521 bits (1341), Expect = e-148
 Identities = 252/252 (100%), Positives = 252/252 (100%)

Query: 1   MALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA 60
           MALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA
Sbjct: 1   MALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA 60

Query: 61  PLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPS 120
           PLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPS
Sbjct: 61  PLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPS 120

Query: 121 LVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPG 180
           LVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPG
Sbjct: 121 LVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPG 180

Query: 181 TYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDW 240
           TYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDW
Sbjct: 181 TYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDW 240

Query: 241 RSQNRAPAGIRP 252
           RSQNRAPAGIRP
Sbjct: 241 RSQNRAPAGIRP 252


>gi|19557668 osteoclast-associated receptor isoform 4 [Homo sapiens]
          Length = 263

 Score =  510 bits (1314), Expect = e-145
 Identities = 251/263 (95%), Positives = 252/263 (95%), Gaps = 11/263 (4%)

Query: 1   MALVLILQLLTLFP-----------PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAW 49
           MALVLILQLLTL+P           PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAW
Sbjct: 1   MALVLILQLLTLWPLCHTDITPSVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAW 60

Query: 50  RFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLE 109
           RFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLE
Sbjct: 61  RFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLE 120

Query: 110 LLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA 169
           LLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA
Sbjct: 121 LLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA 180

Query: 170 DFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVL 229
           DFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVL
Sbjct: 181 DFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVL 240

Query: 230 ISLGALVTFDWRSQNRAPAGIRP 252
           ISLGALVTFDWRSQNRAPAGIRP
Sbjct: 241 ISLGALVTFDWRSQNRAPAGIRP 263


>gi|45580713 osteoclast-associated receptor isoform 3 [Homo sapiens]
          Length = 267

 Score =  509 bits (1310), Expect = e-144
 Identities = 251/267 (94%), Positives = 252/267 (94%), Gaps = 15/267 (5%)

Query: 1   MALVLILQLLTLFP---------------PASYHPKPWLGAQPATVVTPGVNVTLRCRAP 45
           MALVLILQLLTL+P               PASYHPKPWLGAQPATVVTPGVNVTLRCRAP
Sbjct: 1   MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAP 60

Query: 46  QPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPS 105
           QPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPS
Sbjct: 61  QPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPS 120

Query: 106 DVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSA 165
           DVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSA
Sbjct: 121 DVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSA 180

Query: 166 QPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLA 225
           QPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLA
Sbjct: 181 QPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLA 240

Query: 226 GLVLISLGALVTFDWRSQNRAPAGIRP 252
           GLVLISLGALVTFDWRSQNRAPAGIRP
Sbjct: 241 GLVLISLGALVTFDWRSQNRAPAGIRP 267


>gi|45580719 osteoclast-associated receptor isoform 1 [Homo sapiens]
          Length = 286

 Score =  423 bits (1087), Expect = e-119
 Identities = 207/225 (92%), Positives = 208/225 (92%), Gaps = 15/225 (6%)

Query: 1   MALVLILQLLTLFP---------------PASYHPKPWLGAQPATVVTPGVNVTLRCRAP 45
           MALVLILQLLTL+P               PASYHPKPWLGAQPATVVTPGVNVTLRCRAP
Sbjct: 1   MALVLILQLLTLWPLCHTDITPSVAIIVPPASYHPKPWLGAQPATVVTPGVNVTLRCRAP 60

Query: 46  QPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPS 105
           QPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPS
Sbjct: 61  QPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPS 120

Query: 106 DVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSA 165
           DVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSA
Sbjct: 121 DVLELLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSA 180

Query: 166 QPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSG 210
           QPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWE  G
Sbjct: 181 QPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEGEG 225


>gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo
            sapiens]
          Length = 1336

 Score =  144 bits (362), Expect = 1e-34
 Identities = 79/187 (42%), Positives = 106/187 (56%), Gaps = 3/187 (1%)

Query: 20   PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79
            PKPWL A+P++VV  G NVTL CR P     + L K GE   +     +S    F +  +
Sbjct: 969  PKPWLFAEPSSVVPMGQNVTLWCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNI 1028

Query: 80   TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
            +    G Y CCY  PDW   +  QPS+ LELLVT  LP+PSL+A PGP+V PG N++L+C
Sbjct: 1029 SGTSMGRYSCCYH-PDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQC 1087

Query: 140  AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCYYHTPSAPYVLSQ 197
             G L + +FVL +EG   PL+ +  +   ADF +   R    G YSC Y+  S P+  S 
Sbjct: 1088 QGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASN 1147

Query: 198  RSEVLVI 204
             S+ L I
Sbjct: 1148 HSDSLEI 1154



 Score =  123 bits (309), Expect = 1e-28
 Identities = 73/174 (41%), Positives = 95/174 (54%), Gaps = 9/174 (5%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPG-EIAPL--LFRDVSSELAEFF 75
           +PKP+     + VVTPG  VT  C  P     F L+K G EIA     +    +  A F 
Sbjct: 776 YPKPFFKTWASPVVTPGARVTFNCSTPHQHMSFILYKDGSEIASSDRSWASPGASAAHFL 835

Query: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
           +  V    GG Y C Y    +   +WS+PSD +EL+VTE  P+P+L+A PGPVV PG +V
Sbjct: 836 IISVGIGDGGNYSCRY----YDFSIWSEPSDPVELVVTEFYPKPTLLAQPGPVVFPGKSV 891

Query: 136 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYH 187
            LRC G  + M F L +EG   PLQ+R  +   ADF L  +GA   G YSC Y+
Sbjct: 892 ILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLHTVGAEDSGNYSCIYY 945



 Score =  122 bits (306), Expect = 3e-28
 Identities = 79/229 (34%), Positives = 119/229 (51%), Gaps = 8/229 (3%)

Query: 20   PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79
            PKP L AQP  +V PG N+TL+C+   P   F L K G   PL  +  S   A+F++  V
Sbjct: 1065 PKPSLLAQPGPMVAPGENMTLQCQGELPDSTFVLLKEGAQEPLEQQRPSGYRADFWMPAV 1124

Query: 80   TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
                 GIY C Y   D  P   S  SD LE+ VT++ P+PSL A P  +   G +++L+C
Sbjct: 1125 RGEDSGIYSCVYYL-DSTPFAASNHSDSLEIWVTDKPPKPSLSAWPSTMFKLGKDITLQC 1183

Query: 140  AGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLSQ 197
             G L  + FVL  +G  AP Q+        DF +  +  +  G YSC Y   + P + S+
Sbjct: 1184 RGPLPGVEFVLEHDGEEAPQQFSED----GDFVINNVEGKGIGNYSCSYRLQAYPDIWSE 1239

Query: 198  RSEVL-VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNR 245
             S+ L ++      + + T GN+VR  L  +V+++LG ++  +W+   R
Sbjct: 1240 PSDPLELVGAAGPVAQECTVGNIVRSSLIVVVVVALGVVLAIEWKKWPR 1288



 Score =  103 bits (258), Expect = 1e-22
 Identities = 68/187 (36%), Positives = 88/187 (47%), Gaps = 3/187 (1%)

Query: 18   YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE 77
            ++PKP L AQP  VV PG +V LRC+      RF L + G   PL FR VS   A+F L 
Sbjct: 871  FYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSVSGNSADFLLH 930

Query: 78   EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137
             V     G Y C Y          S  S  L + VT+  P+P L A P  VV  G NV+L
Sbjct: 931  TVGAEDSGNYSCIYYETTMS-NRGSYLSMPLMIWVTDTFPKPWLFAEPSSVVPMGQNVTL 989

Query: 138  RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADF--TLLGARAPGTYSCYYHTPSAPYVL 195
             C G +  + ++L++EG A  +Q   S      F  T +   + G YSC YH      + 
Sbjct: 990  WCRGPVHGVGYILHKEGEATSMQLWGSTSNDGAFPITNISGTSMGRYSCCYHPDWTSSIK 1049

Query: 196  SQRSEVL 202
             Q S  L
Sbjct: 1050 IQPSNTL 1056



 Score = 99.0 bits (245), Expect = 4e-21
 Identities = 75/236 (31%), Positives = 110/236 (46%), Gaps = 28/236 (11%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSS--ELAEFFLE 77
           PK WL A+P+ VV  G NV+LRCR P       L+K GE  PL F D +S  +   FFL 
Sbjct: 321 PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLN 380

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137
            VT +  GIY C Y    W   +     + +EL+V ++ P+PSL A P  V   G  ++L
Sbjct: 381 NVTYSDTGIYSCHYLLT-WKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAITL 439

Query: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWA---DFTL--LGARAPGTYSCYYHTPSAP 192
           +C      + F L  E        R + Q ++   DF +  +  +  GTYSC Y   + P
Sbjct: 440 QCRVSHPVLEFSLEWE-------ERETFQKFSVNGDFIISNVDGKGTGTYSCSYRVETHP 492

Query: 193 YVLSQRSEVL-------VISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWR 241
            + S RSE L        ++W      +Y     +RL L   ++  L  ++   W+
Sbjct: 493 NIWSHRSEPLKLMGPAGYLTW------NYVLNEAIRLSLIMQLVALLLVVLWIRWK 542



 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 63/188 (33%), Positives = 97/188 (51%), Gaps = 6/188 (3%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79
           PKP    Q  T   PG NV + C        F LFK G   P+ ++  +  +A F ++ +
Sbjct: 130 PKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNL 189

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
           TP   G+Y  C       P +WS+PS+ L+L+V    P+P+L A PGP++ PG +++LRC
Sbjct: 190 TPEDEGVY-ICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRC 248

Query: 140 AGRLRNMSFVLYR-EGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 196
            G +  M+F L R E +     ++ + +  A+F    L  +  G Y C+Y+   A Y  S
Sbjct: 249 QGPIYGMTFALMRVEDLEKSFYHKKTIKNEANFFFQSLKIQDTGHYLCFYY--DASYRGS 306

Query: 197 QRSEVLVI 204
             S+VL I
Sbjct: 307 LLSDVLKI 314



 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 58/186 (31%), Positives = 87/186 (46%), Gaps = 7/186 (3%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQP-AWRFGLFKPGEIAPLLFRDVSSELAEFFLEE 78
           P+P L  +      P  N+TL CR+P   + +F L K       +     +    F +  
Sbjct: 36  PQPELWIESNYPQAPWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKTFQVSFLIGA 95

Query: 79  VTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLR 138
           +T +  G+YRCCY    W    WS+PS VLEL    +LP+P           PG NV++ 
Sbjct: 96  LTESNAGLYRCCY----WKETGWSKPSKVLELEAPGQLPKPIFWIQAETPALPGCNVNIL 151

Query: 139 CAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVLS 196
           C G L+++ F+L++EG A P+ Y+      A F++  L     G Y C  H    P + S
Sbjct: 152 CHGWLQDLVFMLFKEGYAEPVDYQVPTGTMAIFSIDNLTPEDEGVYICRTHIQMLPTLWS 211

Query: 197 QRSEVL 202
           + S  L
Sbjct: 212 EPSNPL 217



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 66/187 (35%), Positives = 92/187 (49%), Gaps = 12/187 (6%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWR-FGLFKPGEIAPLLFRDVSSEL-AEFFLE 77
           PKP L A+    + P  N+TL CR+P  + + F L K G    +  R  S ++ A F L 
Sbjct: 590 PKPELWAETNFPLAPWKNLTLWCRSPSGSTKEFVLLKDGT-GWIATRPASEQVRAAFPLG 648

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137
            +T +  G Y C      W     S+PS+ LEL+ T+ LP+P + A P      G  + L
Sbjct: 649 ALTQSHTGSYHC----HSWEEMAVSEPSEALELVGTDILPKPVISASP---TIRGQELQL 701

Query: 138 RCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPYVL 195
           RC G L  M F LY+EG   P+Q   +    A FT+  +  +  G YSC  HT   P+  
Sbjct: 702 RCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRMEDKDEGNYSCRTHTEKRPFKW 761

Query: 196 SQRSEVL 202
           S+ SE L
Sbjct: 762 SEPSEPL 768



 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 10/177 (5%)

Query: 16  ASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF--RDVSSELAE 73
           A  +PKP L A P  ++ PG ++ LRC+ P     F L +  ++    +  + + +E A 
Sbjct: 222 AGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLEKSFYHKKTIKNE-AN 280

Query: 74  FFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGA 133
           FF + +     G Y C Y    +   + S   DVL++ VT+  P+  L+A P  VV  G 
Sbjct: 281 FFFQSLKIQDTGHYLCFYYDASYRGSLLS---DVLKIWVTDTFPKTWLLARPSAVVQMGQ 337

Query: 134 NVSLRCAGRLRNMSFVLYREGVAAPLQY--RHSAQPWADFTL--LGARAPGTYSCYY 186
           NVSLRC G +  +   LY++G   PLQ+    S      F L  +     G YSC+Y
Sbjct: 338 NVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHY 394



 Score = 82.8 bits (203), Expect = 3e-16
 Identities = 55/173 (31%), Positives = 78/173 (45%), Gaps = 9/173 (5%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79
           PKP + A P      G  + LRC+       F L+K GE  P+         A F ++ +
Sbjct: 684 PKPVISASPTI---RGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGREAFFTIQRM 740

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
                G Y C     +  P  WS+PS+ LEL++ E  P+P       PVV PGA V+  C
Sbjct: 741 EDKDEGNYSC-RTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASPVVTPGARVTFNC 799

Query: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQPWAD-----FTLLGARAPGTYSCYYH 187
           +   ++MSF+LY++G       R  A P A         +G    G YSC Y+
Sbjct: 800 STPHQHMSFILYKDGSEIASSDRSWASPGASAAHFLIISVGIGDGGNYSCRYY 852


>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 2 isoform b [Homo sapiens]
          Length = 466

 Score =  122 bits (307), Expect = 2e-28
 Identities = 94/242 (38%), Positives = 126/242 (52%), Gaps = 17/242 (7%)

Query: 9   LLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI----APLLF 64
           LL L  P     KP L  QP  +V PG ++TL+C +     RF L+K GE      P   
Sbjct: 212 LLELLVPG-VSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQ 270

Query: 65  RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL-PRPSLVA 123
                  A F L  V+P+ GG YRC Y   +     WS PSD L++L+T +   RPSL  
Sbjct: 271 PQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLS-SEWSAPSDPLDILITGQFYDRPSLSV 328

Query: 124 LPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAP---LQYRHSAQP-WADFTL--LGAR 177
            P P V PG NV+L C  R +  +F+L +EG   P   L+  H AQ   A+F +  + + 
Sbjct: 329 QPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSA 388

Query: 178 APGTYSCYYHTPSAPYVLSQRS---EVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGA 234
             GTY CY    S PY+LS  S   E++V +       DYT  NL+R+G+AGLVL+ LG 
Sbjct: 389 HVGTYRCYSSLSSNPYLLSLPSDPLELVVSASLGQHPQDYTVENLIRMGVAGLVLVVLGI 448

Query: 235 LV 236
           L+
Sbjct: 449 LL 450



 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 71/212 (33%), Positives = 107/212 (50%), Gaps = 18/212 (8%)

Query: 4   VLILQLLTLFP----PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI 59
           VLI   L+L P     A + PKP L A+P +V+  G  VTLRC+    A  + L++  + 
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKS 66

Query: 60  APLLFR-DVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPR 118
           A  + R     +  +F +  +T    G Y C Y   +      S+ SD LEL+VT    +
Sbjct: 67  ASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHS----SEYSDPLELVVTGAYSK 122

Query: 119 PSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHS-----AQPWADFTL 173
           P+L ALP PVV  G NV+L+C  ++    F+L +EG     Q  +S        WA F+ 
Sbjct: 123 PTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFS- 181

Query: 174 LGARAPG---TYSCYYHTPSAPYVLSQRSEVL 202
           +G  +P    +Y CY +  ++PYV S  S++L
Sbjct: 182 VGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLL 213



 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 71/179 (39%), Positives = 90/179 (50%), Gaps = 14/179 (7%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA-PLLFRDVSS----ELAE 73
           + KP L A P+ VVT G NVTL+C +      F L K GE   P      S       A 
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179

Query: 74  FFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGA 133
           F +  V+P++   YRC Y      P VWS PSD+LELLV     +PSL   PGP+V PG 
Sbjct: 180 FSVGPVSPSRRWSYRC-YAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGE 238

Query: 134 NVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFT----LLGARAP---GTYSCY 185
           +++L+C   +    FVLY+EG    LQ R   QP A  +     LG  +P   G Y CY
Sbjct: 239 SLTLQCVSDVGYDRFVLYKEGERDFLQ-RPGWQPQAGLSQANFTLGPVSPSHGGQYRCY 296


>gi|208879429 hypothetical LOC441864 [Homo sapiens]
          Length = 271

 Score =  122 bits (306), Expect = 3e-28
 Identities = 90/240 (37%), Positives = 122/240 (50%), Gaps = 16/240 (6%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA----PLLFRDVSSELAEFF 75
           PKP L A P++VV    NVTLRC  P     F L K G I     PL   D +   AEF 
Sbjct: 27  PKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPL---DSTEGAAEFH 83

Query: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
           L  +     G Y C Y R    P + SQ SDVL LLVT  L +P L       V  G  V
Sbjct: 84  LNNLKVRNAGEYTCEYYRKA-SPHILSQRSDVLLLLVTGHLSKPFLRTYQRGTVTAGGRV 142

Query: 136 SLRCAGRLR---NMSFVLYREGVAAPLQYRHSAQPWADFTLLGARA--PGTYSCYYHTPS 190
           +L+C  R +    + F L + G  +P+Q +  A    DF+L+   A   G YSC Y+   
Sbjct: 143 TLQCQKRDQLFVPIMFALLKAGTPSPIQLQSPAGKEIDFSLVDVTAGDAGNYSCMYYQTK 202

Query: 191 APYVLSQRS---EVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNRAP 247
           +P+  S+ S   E+LV     + SS+Y+ GN VRLGLA ++++ +GA +   W S+N +P
Sbjct: 203 SPFWASEPSDQLEILVTVPPGTTSSNYSLGNFVRLGLAAVIVVIMGAFLVEAWYSRNVSP 262



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 40/95 (42%), Positives = 57/95 (60%), Gaps = 9/95 (9%)

Query: 116 LPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGV----AAPLQYRHSAQPWADF 171
           LP+PSL A P  VV   +NV+LRC    R +SFVL + G+      PL    S +  A+F
Sbjct: 26  LPKPSLSAWPSSVVPANSNVTLRCWTPARGVSFVLRKGGIILESPKPLD---STEGAAEF 82

Query: 172 TL--LGARAPGTYSCYYHTPSAPYVLSQRSEVLVI 204
            L  L  R  G Y+C Y+  ++P++LSQRS+VL++
Sbjct: 83  HLNNLKVRNAGEYTCEYYRKASPHILSQRSDVLLL 117


>gi|32895363 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 2 [Homo sapiens]
          Length = 287

 Score =  118 bits (295), Expect = 6e-27
 Identities = 93/257 (36%), Positives = 127/257 (49%), Gaps = 39/257 (15%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL-----AEFF 75
           K  L A+P +V++ G +VT+RC+    A  + L K G   P    D  + L     A F 
Sbjct: 34  KATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPW---DTQNPLEPKNKARFS 90

Query: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
           +  +T    G YRC Y    + P  WS+PSD LEL+VT    +P+L ALP PVV  G NV
Sbjct: 91  IPSMTEHHAGRYRCYY----YSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 146

Query: 136 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQ--PWADFTLLGARAPGTYS------CYYH 187
           +L+C  RLR   F+L  EG    L +   +Q  P   F  L    P T S      CY  
Sbjct: 147 TLQCGSRLRFDRFILTEEG-DHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGS 205

Query: 188 TPSAPYVLSQRSEVLVI-------------SWEDSGSS----DYTRGNLVRLGLAGLVLI 230
                 V S+ S++L I             +  DSG++    DY   NL+R+G+AGL+L+
Sbjct: 206 RRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGLILV 265

Query: 231 SLGALVTFDWRSQNRAP 247
            LG L+  DW SQ R+P
Sbjct: 266 VLGILIFQDWHSQ-RSP 281



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 17/107 (15%)

Query: 101 WSQPSDVLE-------------LLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMS 147
           WS PS  L+             LL    L + +L A PG V+  G +V++RC G L    
Sbjct: 4   WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63

Query: 148 FVLYREGVAAPLQYRHSAQP--WADFTL--LGARAPGTYSCYYHTPS 190
           + L +EG   P   ++  +P   A F++  +     G Y CYY++P+
Sbjct: 64  YRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPA 110



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 38/103 (36%), Positives = 54/103 (52%), Gaps = 10/103 (9%)

Query: 18  YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------ 71
           ++ KP L A P+ VVT G NVTL+C +     RF L + G+    L   + S+L      
Sbjct: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGD--HKLSWTLDSQLTPSGQF 183

Query: 72  -AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVT 113
            A F +  VTP+   + R CY        VWS+PSD+LE+ V+
Sbjct: 184 QALFPVGPVTPSHRWMLR-CYGSRRHILQVWSEPSDLLEIPVS 225


>gi|32490553 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 1 [Homo sapiens]
          Length = 299

 Score =  118 bits (295), Expect = 6e-27
 Identities = 93/257 (36%), Positives = 127/257 (49%), Gaps = 39/257 (15%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL-----AEFF 75
           K  L A+P +V++ G +VT+RC+    A  + L K G   P    D  + L     A F 
Sbjct: 46  KATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPW---DTQNPLEPKNKARFS 102

Query: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
           +  +T    G YRC Y    + P  WS+PSD LEL+VT    +P+L ALP PVV  G NV
Sbjct: 103 IPSMTEHHAGRYRCYY----YSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 158

Query: 136 SLRCAGRLRNMSFVLYREGVAAPLQYRHSAQ--PWADFTLLGARAPGTYS------CYYH 187
           +L+C  RLR   F+L  EG    L +   +Q  P   F  L    P T S      CY  
Sbjct: 159 TLQCGSRLRFDRFILTEEG-DHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGS 217

Query: 188 TPSAPYVLSQRSEVLVI-------------SWEDSGSS----DYTRGNLVRLGLAGLVLI 230
                 V S+ S++L I             +  DSG++    DY   NL+R+G+AGL+L+
Sbjct: 218 RRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGLILV 277

Query: 231 SLGALVTFDWRSQNRAP 247
            LG L+  DW SQ R+P
Sbjct: 278 VLGILIFQDWHSQ-RSP 293



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 38/103 (36%), Positives = 54/103 (52%), Gaps = 10/103 (9%)

Query: 18  YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------ 71
           ++ KP L A P+ VVT G NVTL+C +     RF L + G+    L   + S+L      
Sbjct: 138 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGD--HKLSWTLDSQLTPSGQF 195

Query: 72  -AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVT 113
            A F +  VTP+   + R CY        VWS+PSD+LE+ V+
Sbjct: 196 QALFPVGPVTPSHRWMLR-CYGSRRHILQVWSEPSDLLEIPVS 237



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 116 LPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP--WADFTL 173
           L + +L A PG V+  G +V++RC G L    + L +EG   P   ++  +P   A F++
Sbjct: 44  LSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSI 103

Query: 174 --LGARAPGTYSCYYHTPS 190
             +     G Y CYY++P+
Sbjct: 104 PSMTEHHAGRYRCYYYSPA 122


>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 2 isoform a [Homo sapiens]
          Length = 483

 Score =  117 bits (293), Expect = 1e-26
 Identities = 93/259 (35%), Positives = 127/259 (49%), Gaps = 34/259 (13%)

Query: 9   LLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI----APLLF 64
           LL L  P     KP L  QP  +V PG ++TL+C +     RF L+K GE      P   
Sbjct: 212 LLELLVPG-VSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQ 270

Query: 65  RDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL-PRPSLVA 123
                  A F L  V+P+ GG YRC Y   +     WS PSD L++L+T +   RPSL  
Sbjct: 271 PQAGLSQANFTLGPVSPSHGGQYRC-YSAHNLS-SEWSAPSDPLDILITGQFYDRPSLSV 328

Query: 124 LPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAP---LQYRHSAQP-WADFTL--LGAR 177
            P P V PG NV+L C  R +  +F+L +EG   P   L+  H AQ   A+F +  + + 
Sbjct: 329 QPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSEHQAQQNQAEFRMGPVTSA 388

Query: 178 APGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSS--------------------DYTRG 217
             GTY CY    S PY+LS  S+ L +   ++  +                    DYT  
Sbjct: 389 HVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLGQHPQDYTVE 448

Query: 218 NLVRLGLAGLVLISLGALV 236
           NL+R+G+AGLVL+ LG L+
Sbjct: 449 NLIRMGVAGLVLVVLGILL 467



 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 71/212 (33%), Positives = 107/212 (50%), Gaps = 18/212 (8%)

Query: 4   VLILQLLTLFP----PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI 59
           VLI   L+L P     A + PKP L A+P +V+  G  VTLRC+    A  + L++  + 
Sbjct: 7   VLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHLYRENKS 66

Query: 60  APLLFR-DVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPR 118
           A  + R     +  +F +  +T    G Y C Y   +      S+ SD LEL+VT    +
Sbjct: 67  ASWVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHS----SEYSDPLELVVTGAYSK 122

Query: 119 PSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHS-----AQPWADFTL 173
           P+L ALP PVV  G NV+L+C  ++    F+L +EG     Q  +S        WA F+ 
Sbjct: 123 PTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAIFS- 181

Query: 174 LGARAPG---TYSCYYHTPSAPYVLSQRSEVL 202
           +G  +P    +Y CY +  ++PYV S  S++L
Sbjct: 182 VGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLL 213



 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 71/179 (39%), Positives = 90/179 (50%), Gaps = 14/179 (7%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA-PLLFRDVSS----ELAE 73
           + KP L A P+ VVT G NVTL+C +      F L K GE   P      S       A 
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179

Query: 74  FFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGA 133
           F +  V+P++   YRC Y      P VWS PSD+LELLV     +PSL   PGP+V PG 
Sbjct: 180 FSVGPVSPSRRWSYRC-YAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGE 238

Query: 134 NVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFT----LLGARAP---GTYSCY 185
           +++L+C   +    FVLY+EG    LQ R   QP A  +     LG  +P   G Y CY
Sbjct: 239 SLTLQCVSDVGYDRFVLYKEGERDFLQ-RPGWQPQAGLSQANFTLGPVSPSHGGQYRCY 296


>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
           member 6 [Homo sapiens]
          Length = 481

 Score =  107 bits (266), Expect = 1e-23
 Identities = 92/261 (35%), Positives = 125/261 (47%), Gaps = 31/261 (11%)

Query: 15  PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI----APLLFRDVSSE 70
           P+    KP L      V+ PG ++TL+C +     RF L+K GE      P         
Sbjct: 218 PSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLS 277

Query: 71  LAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL-PRPSLVALPGPVV 129
            A F L  V+P+ GG YRC Y   +     WS PSD L +L+  ++    SL A PGP V
Sbjct: 278 QANFTLGPVSPSHGGQYRC-YGAHNLS-SEWSAPSDPLNILMAGQIYDTVSLSAQPGPTV 335

Query: 130 GPGANVSLRCAGRLRNMSFVLYREGVA-APLQYR-----HSAQPWADFTLLGARAPGTYS 183
             G NV+L C  R    +F+L +EG A  PL+ R     H  Q     + + +   GTY 
Sbjct: 336 ASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYR 395

Query: 184 CYYHTPSAPYVLSQRSE--VLVISWEDSGSS---------------DYTRGNLVRLGLAG 226
           CY    S P++LS  SE   L++S    GSS               DYT  NL+R+G+AG
Sbjct: 396 CYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGPPSTPASHAKDYTVENLIRMGMAG 455

Query: 227 LVLISLGALVTFDWRSQNRAP 247
           LVL+ LG L+ F+ +   R P
Sbjct: 456 LVLVFLGILL-FEAQHSQRNP 475



 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 70/198 (35%), Positives = 97/198 (48%), Gaps = 21/198 (10%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL-----AEF 74
           PKP L A+P +V++ G  VT+ C+    A  + L K G   PL   D ++ L     A F
Sbjct: 27  PKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQLDKEGSPEPL---DRNNPLEPKNKARF 83

Query: 75  FLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGAN 134
            +  +T    G YRC Y    +    WS+PSD LEL++T    +P+L ALP PVV  G N
Sbjct: 84  SIPSMTQHHAGRYRCHY----YSSAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGN 139

Query: 135 VSLRCAGRLRNMSFVLYREGV-----AAPLQYRHSAQPWADFTLLGARAPG---TYSCYY 186
           ++LRC  +     FVL +EG          Q  HS    A F  +G   P     ++CYY
Sbjct: 140 MTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFP-VGPVTPSHRWRFTCYY 198

Query: 187 HTPSAPYVLSQRSEVLVI 204
           +  + P V S  S+ L I
Sbjct: 199 YYTNTPRVWSHPSDPLEI 216



 Score = 88.6 bits (218), Expect = 5e-18
 Identities = 67/182 (36%), Positives = 94/182 (51%), Gaps = 18/182 (9%)

Query: 18  YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------ 71
           ++ KP L A P+ VV  G N+TLRC + +    F L K GE    L R + S+       
Sbjct: 120 FYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQ--LPRTLDSQQLHSGGF 177

Query: 72  -AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVG 130
            A F +  VTP+    + C Y   +  P VWS PSD LE+L +    +PSL+ L GPV+ 
Sbjct: 178 QALFPVGPVTPSHRWRFTCYYYYTNT-PRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLA 236

Query: 131 PGANVSLRCAGRLRNMSFVLYREG----VAAPLQYRHSAQPWADFTLLGARAP---GTYS 183
           PG +++L+C   +    FVLY+EG    +  P Q   +    A+FT LG  +P   G Y 
Sbjct: 237 PGQSLTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFT-LGPVSPSHGGQYR 295

Query: 184 CY 185
           CY
Sbjct: 296 CY 297


>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
           member 4 [Homo sapiens]
          Length = 499

 Score =  105 bits (261), Expect = 5e-23
 Identities = 91/255 (35%), Positives = 124/255 (48%), Gaps = 31/255 (12%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA----PLLFRDVSSELAEFFL 76
           KP L      VVTPG N+TL+C +     R+ L+K G       P          A F L
Sbjct: 223 KPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTL 282

Query: 77  EEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELP-RPSLVALPGPVVGPGANV 135
             V+ + GG YRC Y   +     WS PSD L++L+  ++  RPSL   PGP V  G  V
Sbjct: 283 SPVSRSYGGQYRC-YGAHNVS-SEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKV 340

Query: 136 SLRCAGRLRNMSFVLYREGVA-APLQYR-----HSAQPWADFTLLGARAPGTYSCYYHTP 189
           +L C       +F+L +EG A  PL+ R     H  Q     + + +   GTY CY    
Sbjct: 341 TLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRS 400

Query: 190 SAPYVLSQRSEVL--VISW-----------EDSGSS----DYTRGNLVRLGLAGLVLISL 232
           S PY+LS  SE L  V+S             DS ++    DYT  NL+R+G+AGLVL+ L
Sbjct: 401 SNPYLLSHPSEPLELVVSGATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFL 460

Query: 233 GALVTFDWRSQNRAP 247
           G L+ F+ +   R+P
Sbjct: 461 GILL-FEAQHSQRSP 474



 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 69/181 (38%), Positives = 96/181 (53%), Gaps = 18/181 (9%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------- 71
           + +P L A P+ VVT GVNVTLRC +     RF L + G+    L   ++S         
Sbjct: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHR--LSWTLNSHQHNHGKFQ 177

Query: 72  AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGP 131
           A F +  +T +  G +RC Y   +  P VWS+PSD L+LLV+    +PSL+ L GPVV P
Sbjct: 178 ALFPMGPLTFSNRGTFRC-YGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236

Query: 132 GANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP-----WADFTL--LGARAPGTYSC 184
           G N++L+C   +  + + LY+EG A  L  R   QP      A+FTL  +     G Y C
Sbjct: 237 GENLTLQCGSDVGYIRYTLYKEG-ADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRC 295

Query: 185 Y 185
           Y
Sbjct: 296 Y 296



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 68/192 (35%), Positives = 92/192 (47%), Gaps = 14/192 (7%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGE-IAPLLFRDVSSE-LAEFFLE 77
           PKP L A+P  V+T    VT+ C+    A  + L K G  ++  + + + SE   +  + 
Sbjct: 27  PKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLSIP 86

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137
            +     G Y C Y+     P  WS+PSD LEL+VT    RP+L ALP PVV  G NV+L
Sbjct: 87  SMMWEHAGRYHCYYQ----SPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTL 141

Query: 138 RCAGRLRNMSFVLYREG------VAAPLQYRHSA-QPWADFTLLGARAPGTYSCYYHTPS 190
           RCA RL    F L  EG           Q+ H   Q       L     GT+ CY +  +
Sbjct: 142 RCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENN 201

Query: 191 APYVLSQRSEVL 202
            PYV S+ S+ L
Sbjct: 202 TPYVWSEPSDPL 213



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 29/100 (29%), Positives = 44/100 (44%), Gaps = 10/100 (10%)

Query: 114 EELPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQPWADFTL 173
           E LP+P L A PGPV+     V++ C G L    + L +EG +     RH  +       
Sbjct: 24  ENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNS---MSRHILKTLESENK 80

Query: 174 LGARAP-------GTYSCYYHTPSAPYVLSQRSEVLVISW 206
           +    P       G Y CYY +P+     S   E++V ++
Sbjct: 81  VKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTAY 120


>gi|46488946 killer cell immunoglobulin-like receptor, three
           domains, long cytoplasmic tail, 3 [Homo sapiens]
          Length = 410

 Score =  104 bits (260), Expect = 6e-23
 Identities = 78/212 (36%), Positives = 106/212 (50%), Gaps = 12/212 (5%)

Query: 1   MALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP-GEI 59
           MA V    L   +P      KP+L A P TVV+ G +VTL+CR+      F L K  G  
Sbjct: 8   MACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMP 67

Query: 60  APLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRP 119
            P L+  +      F +  VTPA  G YRCC   P   P  WS PS+ + ++VT    +P
Sbjct: 68  VPELYNRIFRN--SFLMGPVTPAHAGTYRCCSSHPH-SPTGWSAPSNPVVIMVTGVHRKP 124

Query: 120 SLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAA-PLQ---YRHSAQPWADFTLLG 175
           SL+A PGP+V  G  V L+C   +R   F+L+REG+   PL+     H A    +++ +G
Sbjct: 125 SLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYS-MG 183

Query: 176 ARAP---GTYSCYYHTPSAPYVLSQRSEVLVI 204
              P   GTY C+      PY LS  S+ L I
Sbjct: 184 PMTPALAGTYRCFGSVTHLPYELSAPSDPLDI 215



 Score = 72.4 bits (176), Expect = 4e-13
 Identities = 63/196 (32%), Positives = 88/196 (44%), Gaps = 11/196 (5%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLL-----FRDVSSELAE 73
           H KP L A P  +V  G  V L+C +     RF L + G     L       D  S++  
Sbjct: 121 HRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQV-N 179

Query: 74  FFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGA 133
           + +  +TPA  G YRC +      P   S PSD L+++V     +PSL A PGP V  G 
Sbjct: 180 YSMGPMTPALAGTYRC-FGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGE 238

Query: 134 NVSLRCAGRLRNMSFVLYREGVAAPLQ----YRHSAQPWADFTLLGARAPGTYSCYYHTP 189
           NV+L C+ R     + L RE  A  L+     R +    A+F L      G Y C+    
Sbjct: 239 NVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFR 298

Query: 190 SAPYVLSQRSEVLVIS 205
           + P+  S  S+ L +S
Sbjct: 299 ALPHAWSDPSDPLPVS 314



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 37/99 (37%), Positives = 44/99 (44%), Gaps = 11/99 (11%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPL----LFRDVSSELAEFFL 76
           KP L AQP   V  G NVTL C +      + L +  E   L    + R   +  A F L
Sbjct: 223 KPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPL 282

Query: 77  EEVTPAQGGIYRC--CYRRPDWGPGVWSQPSDVLELLVT 113
             VT   GG YRC   +R     P  WS PSD L + VT
Sbjct: 283 GPVT--HGGNYRCFGSFRAL---PHAWSDPSDPLPVSVT 316


>gi|134268642 killer cell immunoglobulin-like receptor, three
           domains, long cytoplasmic tail, 2 precursor [Homo
           sapiens]
          Length = 455

 Score = 98.2 bits (243), Expect = 6e-21
 Identities = 75/212 (35%), Positives = 104/212 (49%), Gaps = 12/212 (5%)

Query: 1   MALVLILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI- 59
           MA V    L   +P      KP+L A+P+TVV  G +V L+C   +    F L+K     
Sbjct: 8   MACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSH 67

Query: 60  APLLFRDVSSELAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRP 119
            P+    +  E   F +  VTPA  G YRC   RP    G WS PS+ L ++VT    +P
Sbjct: 68  VPIFHGRIFQE--SFIMGPVTPAHAGTYRCRGSRPHSLTG-WSAPSNPLVIMVTGNHRKP 124

Query: 120 SLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAP----LQYRHSAQPWADFTLLG 175
           SL+A PGP++  G  V L+C   +    F L+REG++      +   H     A+F+ +G
Sbjct: 125 SLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFS-IG 183

Query: 176 ARAP---GTYSCYYHTPSAPYVLSQRSEVLVI 204
              P   GTY CY   P +PY LS  S+ L I
Sbjct: 184 PLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDI 215



 Score = 77.8 bits (190), Expect = 8e-15
 Identities = 68/208 (32%), Positives = 93/208 (44%), Gaps = 17/208 (8%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFK------PGEIAPLLFRDVSSELA 72
           H KP L A P  ++  G  V L+C +      F L +      P  +   +   VS   A
Sbjct: 121 HRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSK--A 178

Query: 73  EFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPG 132
            F +  + P   G YRC Y      P   S PSD L++++T    +PSL A PGP V  G
Sbjct: 179 NFSIGPLMPVLAGTYRC-YGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAG 237

Query: 133 ANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP------WADFTLLGARAPGTYSCYY 186
            NV+L C+       + L REG A   + R  A P       ADF L  A   GTY C+ 
Sbjct: 238 ENVTLSCSSWSSYDIYHLSREGEAHERRLR--AVPKVNRTFQADFPLGPATHGGTYRCFG 295

Query: 187 HTPSAPYVLSQRSEVLVISWEDSGSSDY 214
              + P V S  S+ L++S   + SS +
Sbjct: 296 SFRALPCVWSNSSDPLLVSVTGNPSSSW 323


>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 1 [Homo sapiens]
          Length = 489

 Score = 97.8 bits (242), Expect = 8e-21
 Identities = 88/274 (32%), Positives = 124/274 (45%), Gaps = 51/274 (18%)

Query: 6   ILQLLTLFPPASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFR 65
           +L+LL L        KP L  QP  +V PG ++TL+C +     RF L+K GE   L   
Sbjct: 214 LLELLVL----GVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLP 269

Query: 66  DVSSEL----AEFFLEEVTPAQGGIYRC--CYRRPDWGPGVWSQPSDVLELLVTEELP-R 118
               +     A F L  V+ + GG YRC   Y         WS PSD L++L+  +   R
Sbjct: 270 GPQPQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSS----EWSAPSDPLDILIAGQFRGR 325

Query: 119 PSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVA-APLQYR--HSAQPW-ADFTL- 173
           P +   PGP V  G NV+L C       +F+L + G A APL+ R  H    + A+F + 
Sbjct: 326 PFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMS 385

Query: 174 -LGARAPGTYSCYYHTPSAPYVLSQRSEVLVISWEDSGSS-------------------- 212
            + +   GTY CY    S PY+LS  S+ L +    +  +                    
Sbjct: 386 PVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSGAAETLSPPQNKSDSKAGAANTLSP 445

Query: 213 ----------DYTRGNLVRLGLAGLVLISLGALV 236
                     DYT  NL+R+G+AGLVL+ LG L+
Sbjct: 446 SQNKTASHPQDYTVENLIRMGIAGLVLVVLGILL 479



 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 76/214 (35%), Positives = 111/214 (51%), Gaps = 20/214 (9%)

Query: 4   VLILQLLTLFP----PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI 59
           VLI   L+L P     A   PKP L A+P +V+T G  VTL C+       + L++  + 
Sbjct: 7   VLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRLYREKKT 66

Query: 60  APLLFRDVSSELA---EFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL 116
           AP + R +  E+    +F +  +T    G YRC Y     G   WS+PSD LEL+VT   
Sbjct: 67  APWITR-IPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAG---WSEPSDPLELVVTGAY 122

Query: 117 PRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP----WADFT 172
            +P+L ALP PVV  G NV+L C  ++   SF+L +EG     Q  +S QP    W+   
Sbjct: 123 IKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNS-QPRTHGWSRAI 181

Query: 173 L-LGARAPG---TYSCYYHTPSAPYVLSQRSEVL 202
             +G  +P    +Y CY +  ++P+V S  S++L
Sbjct: 182 FSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLL 215



 Score = 85.9 bits (211), Expect = 3e-17
 Identities = 66/175 (37%), Positives = 85/175 (48%), Gaps = 12/175 (6%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIA-PLLF----RDVSSELAEFF 75
           KP L A P+ VVT G NVTL C +      F L K GE   P       R      A F 
Sbjct: 124 KPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRAIFS 183

Query: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
           +  V+P++   YRC Y      P VWS PSD+LELLV     +PSL   PGP+V PG ++
Sbjct: 184 VGPVSPSRRWSYRC-YAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGESL 242

Query: 136 SLRCAGRLRNMSFVLYREG----VAAPLQYRHSAQPWADFTL--LGARAPGTYSC 184
           +L+C   +    FVLY+EG    +  P     +    A+FTL  +     G Y C
Sbjct: 243 TLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRC 297


>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 1 [Homo sapiens]
          Length = 632

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 70/198 (35%), Positives = 99/198 (50%), Gaps = 21/198 (10%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL-----AEF 74
           PKP L A+P +V++ G  VT+ C+  Q A  + L K G   PL   D ++ L     A F
Sbjct: 27  PKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPL---DRNNPLEPKNKARF 83

Query: 75  FLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGAN 134
            +  +T    G YRC Y    +    WS+PSD LE+++T    +P+L ALP PVV  G N
Sbjct: 84  SIPSMTEHHAGRYRCHY----YSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGN 139

Query: 135 VSLRCAGRLRNMSFVLYREGV-----AAPLQYRHSAQPWADFTLLGARAPG---TYSCYY 186
           ++LRC  +     FVL +EG          Q  HS    A F  +G   P     ++CYY
Sbjct: 140 MTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFP-VGPVTPSHRWRFTCYY 198

Query: 187 HTPSAPYVLSQRSEVLVI 204
           +  + P+V S  S+ L I
Sbjct: 199 YYTNTPWVWSHPSDPLEI 216



 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 80/237 (33%), Positives = 109/237 (45%), Gaps = 15/237 (6%)

Query: 15  PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI----APLLFRDVSSE 70
           P+    KP L      V+ PG ++TL+C +     RF L+K GE      P         
Sbjct: 218 PSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLS 277

Query: 71  LAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL-PRPSLVALPGPVV 129
            A F L  V+P+ GG YRC Y   +     WS PSD L +L+  ++    SL A PGP V
Sbjct: 278 QANFTLGPVSPSNGGQYRC-YGAHNLS-SEWSAPSDPLNILMAGQIYDTVSLSAQPGPTV 335

Query: 130 GPGANVSLRCAGRLRNMSFVLYREGVA-APLQYR-----HSAQPWADFTLLGARAPGTYS 183
             G NV+L C    +  +F+L +EG A  PL+ R     H  Q     + + +   GTY 
Sbjct: 336 ASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYR 395

Query: 184 CYYHTPSAPYVLSQRSE--VLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTF 238
           CY    S P++LS  SE   LV+S    GSS    G     GL   + + +G  V F
Sbjct: 396 CYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAF 452



 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 67/181 (37%), Positives = 93/181 (51%), Gaps = 18/181 (9%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------- 71
           + KP L A P+ VV  G N+TLRC + +    F L K GE    L R + S+        
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQ--LPRTLDSQQLHSRGFQ 178

Query: 72  AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGP 131
           A F +  VTP+    + C Y   +  P VWS PSD LE+L +    +PSL+ L GPV+ P
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNT-PWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAP 237

Query: 132 GANVSLRCAGRLRNMSFVLYREG----VAAPLQYRHSAQPWADFTLLGARAP---GTYSC 184
           G +++L+C   +    FVLY+EG    +  P Q   +    A+FT LG  +P   G Y C
Sbjct: 238 GQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFT-LGPVSPSNGGQYRC 296

Query: 185 Y 185
           Y
Sbjct: 297 Y 297


>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 2 [Homo sapiens]
          Length = 631

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 70/198 (35%), Positives = 99/198 (50%), Gaps = 21/198 (10%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL-----AEF 74
           PKP L A+P +V++ G  VT+ C+  Q A  + L K G   PL   D ++ L     A F
Sbjct: 27  PKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPL---DRNNPLEPKNKARF 83

Query: 75  FLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGAN 134
            +  +T    G YRC Y    +    WS+PSD LE+++T    +P+L ALP PVV  G N
Sbjct: 84  SIPSMTEHHAGRYRCHY----YSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGN 139

Query: 135 VSLRCAGRLRNMSFVLYREGV-----AAPLQYRHSAQPWADFTLLGARAPG---TYSCYY 186
           ++LRC  +     FVL +EG          Q  HS    A F  +G   P     ++CYY
Sbjct: 140 MTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFP-VGPVTPSHRWRFTCYY 198

Query: 187 HTPSAPYVLSQRSEVLVI 204
           +  + P+V S  S+ L I
Sbjct: 199 YYTNTPWVWSHPSDPLEI 216



 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 80/237 (33%), Positives = 109/237 (45%), Gaps = 15/237 (6%)

Query: 15  PASYHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEI----APLLFRDVSSE 70
           P+    KP L      V+ PG ++TL+C +     RF L+K GE      P         
Sbjct: 218 PSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLS 277

Query: 71  LAEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL-PRPSLVALPGPVV 129
            A F L  V+P+ GG YRC Y   +     WS PSD L +L+  ++    SL A PGP V
Sbjct: 278 QANFTLGPVSPSNGGQYRC-YGAHNLS-SEWSAPSDPLNILMAGQIYDTVSLSAQPGPTV 335

Query: 130 GPGANVSLRCAGRLRNMSFVLYREGVA-APLQYR-----HSAQPWADFTLLGARAPGTYS 183
             G NV+L C    +  +F+L +EG A  PL+ R     H  Q     + + +   GTY 
Sbjct: 336 ASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYR 395

Query: 184 CYYHTPSAPYVLSQRSE--VLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTF 238
           CY    S P++LS  SE   LV+S    GSS    G     GL   + + +G  V F
Sbjct: 396 CYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEVLIGVSVAF 452



 Score = 88.2 bits (217), Expect = 6e-18
 Identities = 67/181 (37%), Positives = 93/181 (51%), Gaps = 18/181 (9%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------- 71
           + KP L A P+ VV  G N+TLRC + +    F L K GE    L R + S+        
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQ--LPRTLDSQQLHSRGFQ 178

Query: 72  AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGP 131
           A F +  VTP+    + C Y   +  P VWS PSD LE+L +    +PSL+ L GPV+ P
Sbjct: 179 ALFPVGPVTPSHRWRFTCYYYYTNT-PWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAP 237

Query: 132 GANVSLRCAGRLRNMSFVLYREG----VAAPLQYRHSAQPWADFTLLGARAP---GTYSC 184
           G +++L+C   +    FVLY+EG    +  P Q   +    A+FT LG  +P   G Y C
Sbjct: 238 GQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFT-LGPVSPSNGGQYRC 296

Query: 185 Y 185
           Y
Sbjct: 297 Y 297


>gi|66267727 killer cell immunoglobulin-like receptor, two domains,
           long cytoplasmic tail, 5B precursor [Homo sapiens]
          Length = 375

 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 75/199 (37%), Positives = 98/199 (49%), Gaps = 12/199 (6%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP-GEIAPLLFRDVSSELAEFFLEEV 79
           KP L A P+ VV  G +VTL CR+      F L+K  G   P L+  +  +     +  V
Sbjct: 28  KPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNKIFWK--SILMGPV 85

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
           TPA  G YRC    P   P  WS PS+ L ++VT    +PSL A PGP V  G NV+L C
Sbjct: 86  TPAHAGTYRCRGSHPR-SPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVALSC 144

Query: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQP------WADFTLLGARAPGTYSCYYHTPSAPY 193
           + R     + L REG A   + R  A P       ADF L  A   GTY+C+     +PY
Sbjct: 145 SSRSSFDMYHLSREGRAH--EPRLPAVPSVDGTFQADFPLGPATHGGTYTCFSSLHDSPY 202

Query: 194 VLSQRSEVLVISWEDSGSS 212
             S  S+ L++S   + SS
Sbjct: 203 EWSDPSDPLLVSVTGNSSS 221


>gi|11968154 killer cell immunoglobulin-like receptor, two domains,
           long cytoplasmic tail, 5A [Homo sapiens]
          Length = 375

 Score = 95.5 bits (236), Expect = 4e-20
 Identities = 73/197 (37%), Positives = 96/197 (48%), Gaps = 8/197 (4%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP-GEIAPLLFRDVSSELAEFFLEEV 79
           KP L A P+ VV  G +VTL CR+      F L+K  G   P L+  +  +     +  V
Sbjct: 28  KPLLSAWPSAVVPRGGHVTLLCRSRLGFTIFSLYKEDGVPVPELYNKIFWK--SILMGPV 85

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
           TPA  G YRC    P   P  WS PS+ L ++VT    +PSL A PGP V  G NV+L C
Sbjct: 86  TPAHAGTYRCRGSHPR-SPIEWSAPSNPLVIVVTGLFGKPSLSAQPGPTVRTGENVTLSC 144

Query: 140 AGRLRNMSFVLYREGVA----APLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVL 195
           + R     + L REG A     P     +    ADF L  A   GTY+C+     +PY  
Sbjct: 145 SSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQADFPLGPATHGGTYTCFGSLHDSPYEW 204

Query: 196 SQRSEVLVISWEDSGSS 212
           S  S+ L++S   + SS
Sbjct: 205 SDPSDPLLVSVTGNSSS 221


>gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B,
           member 4 isoform 2 [Homo sapiens]
          Length = 447

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 68/191 (35%), Positives = 98/191 (51%), Gaps = 12/191 (6%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDV--SSELAEFFLE 77
           PKP L A+P +V++ G +VT+ C+    A  + L K    AP   ++       A F + 
Sbjct: 27  PKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSIP 86

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137
            +T    G YRC YR P      WSQPSD LEL++T    +P+L ALP P+V  G +V+L
Sbjct: 87  SMTEDYAGRYRCYYRSPVG----WSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTL 142

Query: 138 RCAGRLRNMSFVLYREGVAAPLQY---RHSAQP-WADFTLLGARA--PGTYSCYYHTPSA 191
            C  R    +F+L +E  A PL +    H AQ   A+F +    +   GTY C+     +
Sbjct: 143 LCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFS 202

Query: 192 PYVLSQRSEVL 202
            Y+LS  S+ L
Sbjct: 203 HYLLSHPSDPL 213



 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 44/119 (36%), Positives = 56/119 (47%), Gaps = 7/119 (5%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF----RDVSSELAEF 74
           + KP L A P+ +VT G +VTL C++  P   F L K     PLL            AEF
Sbjct: 121 YSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEF 180

Query: 75  FLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL--PRPSLVALPGPVVGP 131
            +  VT   GG YR C+    +   + S PSD LEL+V+  L  PRPS         GP
Sbjct: 181 PMSPVTSVHGGTYR-CFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGP 238



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 4/78 (5%)

Query: 116 LPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP--WADFTL 173
           LP+P+L A PG V+  G +V++ C G L    + L +E   AP   ++  +P   A F++
Sbjct: 26  LPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSI 85

Query: 174 --LGARAPGTYSCYYHTP 189
             +     G Y CYY +P
Sbjct: 86  PSMTEDYAGRYRCYYRSP 103


>gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B,
           member 4 isoform 1 [Homo sapiens]
          Length = 448

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 68/191 (35%), Positives = 98/191 (51%), Gaps = 12/191 (6%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDV--SSELAEFFLE 77
           PKP L A+P +V++ G +VT+ C+    A  + L K    AP   ++       A F + 
Sbjct: 27  PKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSIP 86

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSL 137
            +T    G YRC YR P      WSQPSD LEL++T    +P+L ALP P+V  G +V+L
Sbjct: 87  SMTEDYAGRYRCYYRSPVG----WSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVTL 142

Query: 138 RCAGRLRNMSFVLYREGVAAPLQY---RHSAQP-WADFTLLGARA--PGTYSCYYHTPSA 191
            C  R    +F+L +E  A PL +    H AQ   A+F +    +   GTY C+     +
Sbjct: 143 LCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGFS 202

Query: 192 PYVLSQRSEVL 202
            Y+LS  S+ L
Sbjct: 203 HYLLSHPSDPL 213



 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 44/119 (36%), Positives = 56/119 (47%), Gaps = 7/119 (5%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLF----RDVSSELAEF 74
           + KP L A P+ +VT G +VTL C++  P   F L K     PLL            AEF
Sbjct: 121 YSKPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEF 180

Query: 75  FLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEEL--PRPSLVALPGPVVGP 131
            +  VT   GG YR C+    +   + S PSD LEL+V+  L  PRPS         GP
Sbjct: 181 PMSPVTSVHGGTYR-CFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGP 238



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 4/78 (5%)

Query: 116 LPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP--WADFTL 173
           LP+P+L A PG V+  G +V++ C G L    + L +E   AP   ++  +P   A F++
Sbjct: 26  LPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDRQNPLEPKNKARFSI 85

Query: 174 --LGARAPGTYSCYYHTP 189
             +     G Y CYY +P
Sbjct: 86  PSMTEDYAGRYRCYYRSP 103


>gi|124107604 killer cell immunoglobulin-like receptor, two domains,
           long cytoplasmic tail, 4 isoform b [Homo sapiens]
          Length = 273

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 74/201 (36%), Positives = 96/201 (47%), Gaps = 12/201 (5%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP-GEIAPLLFRDVSSELAEFFLEEV 79
           KP+  A P+ VV  G +VTLRC   +    F L+K  G   P L+  +      F +  V
Sbjct: 30  KPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWN--SFLISPV 87

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
           TPA  G YRC    P   P  WS PS+ L ++VT    +PSL A PGP V  G NV+L C
Sbjct: 88  TPAHAGTYRCRGFHPH-SPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSC 146

Query: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQP------WADFTLLGARAPGTYSCYYHTPSAPY 193
           + +     + L REG A  L  R  A P       ADF L  A    TY C+     +PY
Sbjct: 147 SSQSSFDIYHLSREGEAHEL--RLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPY 204

Query: 194 VLSQRSEVLVISWEDSGSSDY 214
             S  S+ L +S   + SS +
Sbjct: 205 EWSDPSDPLPVSVTGNPSSSW 225



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 1/96 (1%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE- 77
           + KP L A+P   V  G NVTL C +      + L + GE   L    V S    F  + 
Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVT 113
            + PA  G    C+      P  WS PSD L + VT
Sbjct: 183 PLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVT 218


>gi|124107606 killer cell immunoglobulin-like receptor, two domains,
           long cytoplasmic tail, 4 isoform a [Homo sapiens]
          Length = 377

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 74/201 (36%), Positives = 96/201 (47%), Gaps = 12/201 (5%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP-GEIAPLLFRDVSSELAEFFLEEV 79
           KP+  A P+ VV  G +VTLRC   +    F L+K  G   P L+  +      F +  V
Sbjct: 30  KPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWN--SFLISPV 87

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
           TPA  G YRC    P   P  WS PS+ L ++VT    +PSL A PGP V  G NV+L C
Sbjct: 88  TPAHAGTYRCRGFHPH-SPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSC 146

Query: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQP------WADFTLLGARAPGTYSCYYHTPSAPY 193
           + +     + L REG A  L  R  A P       ADF L  A    TY C+     +PY
Sbjct: 147 SSQSSFDIYHLSREGEAHEL--RLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPY 204

Query: 194 VLSQRSEVLVISWEDSGSSDY 214
             S  S+ L +S   + SS +
Sbjct: 205 EWSDPSDPLPVSVTGNPSSSW 225



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 1/96 (1%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE- 77
           + KP L A+P   V  G NVTL C +      + L + GE   L    V S    F  + 
Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVT 113
            + PA  G    C+      P  WS PSD L + VT
Sbjct: 183 PLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVT 218


>gi|124107610 killer cell immunoglobulin-like receptor, two domains,
           long cytoplasmic tail, 4 isoform c [Homo sapiens]
          Length = 342

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 74/201 (36%), Positives = 96/201 (47%), Gaps = 12/201 (5%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP-GEIAPLLFRDVSSELAEFFLEEV 79
           KP+  A P+ VV  G +VTLRC   +    F L+K  G   P L+  +      F +  V
Sbjct: 30  KPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWN--SFLISPV 87

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
           TPA  G YRC    P   P  WS PS+ L ++VT    +PSL A PGP V  G NV+L C
Sbjct: 88  TPAHAGTYRCRGFHPH-SPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRAGENVTLSC 146

Query: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQP------WADFTLLGARAPGTYSCYYHTPSAPY 193
           + +     + L REG A  L  R  A P       ADF L  A    TY C+     +PY
Sbjct: 147 SSQSSFDIYHLSREGEAHEL--RLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPY 204

Query: 194 VLSQRSEVLVISWEDSGSSDY 214
             S  S+ L +S   + SS +
Sbjct: 205 EWSDPSDPLPVSVTGNPSSSW 225



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 1/96 (1%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLE- 77
           + KP L A+P   V  G NVTL C +      + L + GE   L    V S    F  + 
Sbjct: 123 YEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQADF 182

Query: 78  EVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVT 113
            + PA  G    C+      P  WS PSD L + VT
Sbjct: 183 PLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVT 218


>gi|143770741 glycoprotein VI (platelet) isoform 1 [Homo sapiens]
          Length = 620

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 65/187 (34%), Positives = 95/187 (50%), Gaps = 18/187 (9%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79
           PKP L A P+++V     VTLRC+ P       L++  +++   ++D     A  F+  +
Sbjct: 26  PKPSLQALPSSLVPLEKPVTLRCQGPPGV---DLYRLEKLSSSRYQDQ----AVLFIPAM 78

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
             +  G YRC Y+       +WS PSD LEL+ T    +PSL A PGP V  G +V+L+C
Sbjct: 79  KRSLAGRYRCSYQNGS----LWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQC 134

Query: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQPW--ADFTLLGARA--PGTYSCYYHTPSAPYVL 195
             R     F LY+EG  AP +   + + W  A F ++   A   GTY CY  +   PY+ 
Sbjct: 135 QTRYGFDQFALYKEGDPAPYK---NPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLW 191

Query: 196 SQRSEVL 202
           S  S+ L
Sbjct: 192 SAPSDPL 198



 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 44/110 (40%), Positives = 56/110 (50%), Gaps = 4/110 (3%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVT 80
           KP L AQP   V+ G +VTL+C+      +F L+K G+ AP    +     A F +  VT
Sbjct: 113 KPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYR-ASFPIITVT 171

Query: 81  PAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVAL--PGPV 128
            A  G YRC Y      P +WS PSD LEL+VT     PS +    P PV
Sbjct: 172 AAHSGTYRC-YSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPV 220



 Score = 29.3 bits (64), Expect = 3.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 116 LPRPSLVALPGPVVGPGANVSLRCAG-------RLRNMSFVLYRE 153
           LP+PSL ALP  +V     V+LRC G       RL  +S   Y++
Sbjct: 25  LPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSRYQD 69


>gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens]
          Length = 339

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 65/187 (34%), Positives = 95/187 (50%), Gaps = 18/187 (9%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEV 79
           PKP L A P+++V     VTLRC+ P       L++  +++   ++D     A  F+  +
Sbjct: 26  PKPSLQALPSSLVPLEKPVTLRCQGPPGV---DLYRLEKLSSSRYQDQ----AVLFIPAM 78

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
             +  G YRC Y+       +WS PSD LEL+ T    +PSL A PGP V  G +V+L+C
Sbjct: 79  KRSLAGRYRCSYQNGS----LWSLPSDQLELVATGVFAKPSLSAQPGPAVSSGGDVTLQC 134

Query: 140 AGRLRNMSFVLYREGVAAPLQYRHSAQPW--ADFTLLGARA--PGTYSCYYHTPSAPYVL 195
             R     F LY+EG  AP +   + + W  A F ++   A   GTY CY  +   PY+ 
Sbjct: 135 QTRYGFDQFALYKEGDPAPYK---NPERWYRASFPIITVTAAHSGTYRCYSFSSRDPYLW 191

Query: 196 SQRSEVL 202
           S  S+ L
Sbjct: 192 SAPSDPL 198



 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 65/231 (28%), Positives = 94/231 (40%), Gaps = 53/231 (22%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELAEFFLEEVT 80
           KP L AQP   V+ G +VTL+C+      +F L+K G+ AP    +     A F +  VT
Sbjct: 113 KPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPAPYKNPERWYR-ASFPIITVT 171

Query: 81  PAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRCA 140
            A  G YRC Y      P +WS PSD LEL+VT     PS +    P             
Sbjct: 172 AAHSGTYRC-YSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPP------------- 217

Query: 141 GRLRNMSFVLYREGVAAPLQYRHSAQPWADFTLLGARAPGTYSCYYHTPSAPYVLSQRSE 200
                                     P A+F+   A    +++    T       ++ S 
Sbjct: 218 -------------------------SPVAEFSEATAELTVSFTNEVFT-------TETSR 245

Query: 201 VLVISWEDSGS------SDYTRGNLVRLGLAGLVLISLGALVTFDWRSQNR 245
            +  S ++S S        YT+GNLVR+ L  ++LI L   +  DW S+ +
Sbjct: 246 SITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAGFLAEDWHSRRK 296



 Score = 29.3 bits (64), Expect = 3.4
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 116 LPRPSLVALPGPVVGPGANVSLRCAG-------RLRNMSFVLYRE 153
           LP+PSL ALP  +V     V+LRC G       RL  +S   Y++
Sbjct: 25  LPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLEKLSSSRYQD 69


>gi|32895365 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 4 [Homo sapiens]
          Length = 253

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 56/139 (40%), Positives = 75/139 (53%), Gaps = 12/139 (8%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL-----AEFF 75
           K  L A+P +V++ G +VT+RC+    A  + L K G   P    D  + L     A F 
Sbjct: 34  KATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPW---DTQNPLEPKNKARFS 90

Query: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
           +  +T    G YRC Y    + P  WS+PSD LEL+VT    +P+L ALP PVV  G NV
Sbjct: 91  IPSMTEHHAGRYRCYY----YSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 146

Query: 136 SLRCAGRLRNMSFVLYREG 154
           +L+C  RLR   F+L  EG
Sbjct: 147 TLQCGSRLRFDRFILTEEG 165



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 17/107 (15%)

Query: 101 WSQPSDVLE-------------LLVTEELPRPSLVALPGPVVGPGANVSLRCAGRLRNMS 147
           WS PS  L+             LL    L + +L A PG V+  G +V++RC G L    
Sbjct: 4   WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63

Query: 148 FVLYREGVAAPLQYRHSAQP--WADFTL--LGARAPGTYSCYYHTPS 190
           + L +EG   P   ++  +P   A F++  +     G Y CYY++P+
Sbjct: 64  YRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPA 110



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 10/105 (9%)

Query: 18  YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------ 71
           ++ KP L A P+ VVT G NVTL+C +     RF L + G+    L   + S+L      
Sbjct: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGD--HKLSWTLDSQLTPSGQF 183

Query: 72  -AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEE 115
            A F +  VTP+   + R CY        VWS+PSD+LE+ V+ E
Sbjct: 184 QALFPVGPVTPSHRWMLR-CYGSRRHILQVWSEPSDLLEIPVSGE 227


>gi|32895361 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 3 [Homo sapiens]
          Length = 265

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 56/139 (40%), Positives = 75/139 (53%), Gaps = 12/139 (8%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL-----AEFF 75
           K  L A+P +V++ G +VT+RC+    A  + L K G   P    D  + L     A F 
Sbjct: 46  KATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPW---DTQNPLEPKNKARFS 102

Query: 76  LEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANV 135
           +  +T    G YRC Y    + P  WS+PSD LEL+VT    +P+L ALP PVV  G NV
Sbjct: 103 IPSMTEHHAGRYRCYY----YSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 158

Query: 136 SLRCAGRLRNMSFVLYREG 154
           +L+C  RLR   F+L  EG
Sbjct: 159 TLQCGSRLRFDRFILTEEG 177



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 10/105 (9%)

Query: 18  YHPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------ 71
           ++ KP L A P+ VVT G NVTL+C +     RF L + G+    L   + S+L      
Sbjct: 138 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGD--HKLSWTLDSQLTPSGQF 195

Query: 72  -AEFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEE 115
            A F +  VTP+   + R CY        VWS+PSD+LE+ V+ E
Sbjct: 196 QALFPVGPVTPSHRWMLR-CYGSRRHILQVWSEPSDLLEIPVSGE 239



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 116 LPRPSLVALPGPVVGPGANVSLRCAGRLRNMSFVLYREGVAAPLQYRHSAQP--WADFTL 173
           L + +L A PG V+  G +V++RC G L    + L +EG   P   ++  +P   A F++
Sbjct: 44  LSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSI 103

Query: 174 --LGARAPGTYSCYYHTPS 190
             +     G Y CYY++P+
Sbjct: 104 PSMTEHHAGRYRCYYYSPA 122


>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
          Length = 328

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 69/191 (36%), Positives = 94/191 (49%), Gaps = 10/191 (5%)

Query: 21  KPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKP-GEIAPLLFRDVSSELAEFFLEEV 79
           KP+L A P+ VV+ G +V L+CR+      F L K  G   P L+  V       F+  V
Sbjct: 28  KPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSLSKEDGMPVPELYNRVFRNTV--FIGPV 85

Query: 80  TPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPGANVSLRC 139
           TPA  G YRC    P +  G WS PS+ L ++VT    +PSL+A PGP+V     V L+C
Sbjct: 86  TPAHAGTYRCRGSHPHFLTG-WSAPSNPLVIMVTGVHRKPSLLAHPGPLVKSEETVILQC 144

Query: 140 AGRLRNMSFVLYREG----VAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTPSAPY 193
              +    F+L+REG            H     A+F++  +     GTY CY   P +PY
Sbjct: 145 WSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYGSVPHSPY 204

Query: 194 VLSQRSEVLVI 204
            LS  S+ L I
Sbjct: 205 QLSAPSDPLDI 215



 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 65/201 (32%), Positives = 94/201 (46%), Gaps = 13/201 (6%)

Query: 19  HPKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSEL------A 72
           H KP L A P  +V     V L+C +      F L + G+    L   ++ EL      A
Sbjct: 121 HRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTL--RLTGELHDGVSKA 178

Query: 73  EFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPG 132
            F +  +T    G YRC Y      P   S PSD L++++T    +PSL A P P+V  G
Sbjct: 179 NFSIGRMTQDLAGTYRC-YGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPMVKAG 237

Query: 133 ANVSLRCAGRLRNMSFVLYREGVAAPLQY----RHSAQPWADFTLLGARAPGTYSCYYHT 188
            +V+L C+ R     + L REG A  L++    + +    A+F L  A   GTY C+   
Sbjct: 238 ESVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPATHGGTYRCFGSF 297

Query: 189 PSAPYVLSQRSEVLVISWEDS 209
             +PY  S  S+ L++S  DS
Sbjct: 298 RDSPYEWSDLSDPLLVSVTDS 318


>gi|19743861 Fc alpha receptor isoform d [Homo sapiens]
          Length = 275

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 72/233 (30%), Positives = 117/233 (50%), Gaps = 18/233 (7%)

Query: 20  PKPWLGAQPATVVTPGVNVTLRCRAPQPAWRFGLFKPGEIAPLLFRDVSSELA------- 72
           P P++ A+ + V+    +V ++C+A + A+   L     I    +R++   L        
Sbjct: 15  PMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMI---IKNSTYREIGRRLKFWNETDP 71

Query: 73  EFFLEEVTPAQGGIYRCCYRRPDWGPGVWSQPSDVLELLVTEELPRPSLVALPGPVVGPG 132
           EF ++ +   + G Y+C YR   +      + SD LEL+VT    +P L A  G V+ PG
Sbjct: 72  EFVIDHMDANKAGRYQCQYRIGHYR----FRYSDTLELVVTGLYGKPFLSADRGLVLMPG 127

Query: 133 ANVSLRCAG-RLRNMSFVLYREGVAAPLQYRHSAQPWADFTL--LGARAPGTYSCYYHTP 189
            N+SL C+   +    F L +EG  +  Q++    P A+F+L  +     G Y CY    
Sbjct: 128 ENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHP-ANFSLGPVDLNVSGIYRCYGWYN 186

Query: 190 SAPYVLSQRSEVLVISWEDSGSSDYTRGNLVRLGLAGLVLISLGALVTFDWRS 242
            +PY+ S  S  L +   DS   DYT  NL+R+ +AGLVL++L A++  +W S
Sbjct: 187 RSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHS 239


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,721,398
Number of Sequences: 37866
Number of extensions: 631468
Number of successful extensions: 2125
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1476
Number of HSP's gapped (non-prelim): 244
length of query: 252
length of database: 18,247,518
effective HSP length: 100
effective length of query: 152
effective length of database: 14,460,918
effective search space: 2198059536
effective search space used: 2198059536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.