Guide to the Human Genome
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Search of human proteins with 195546915

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195546915 hypothetical protein LOC125704 [Homo sapiens]
         (419 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195546915 hypothetical protein LOC125704 [Homo sapiens]            862   0.0  
gi|224922839 hypothetical protein LOC138311 [Homo sapiens]             88   1e-17
gi|165932391 family with sequence similarity 69, member A [Homo ...    80   4e-15
gi|197333863 hypothetical protein LOC205428 isoform b [Homo sapi...    38   0.020
gi|27734895 hypothetical protein LOC205428 isoform a [Homo sapiens]    38   0.020
gi|27477111 step II splicing factor SLU7 [Homo sapiens]                31   1.8  
gi|4502735 cyclin-dependent kinase 4 [Homo sapiens]                    31   2.4  
gi|226423905 splA/ryanodine receptor domain and SOCS box contain...    30   5.3  
gi|226423903 splA/ryanodine receptor domain and SOCS box contain...    30   5.3  
gi|14249178 splA/ryanodine receptor domain and SOCS box containi...    30   5.3  
gi|193804854 hypothetical protein LOC79742 isoform 1 [Homo sapiens]    30   5.3  
gi|28557802 sterile alpha motif domain containing 14 [Homo sapiens]    29   7.0  
gi|23592242 vestigial-like 2 isoform 2 [Homo sapiens]                  29   9.1  

>gi|195546915 hypothetical protein LOC125704 [Homo sapiens]
          Length = 419

 Score =  862 bits (2227), Expect = 0.0
 Identities = 419/419 (100%), Positives = 419/419 (100%)

Query: 1   MARAAGARGPAGWCRRRGRCGRGTLLAFAAWTAGWVLAAALLLRAHPGVLSERCTDEKSR 60
           MARAAGARGPAGWCRRRGRCGRGTLLAFAAWTAGWVLAAALLLRAHPGVLSERCTDEKSR
Sbjct: 1   MARAAGARGPAGWCRRRGRCGRGTLLAFAAWTAGWVLAAALLLRAHPGVLSERCTDEKSR 60

Query: 61  RILAALCQDYQGGTLAGDLCEDLCVAGELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEE 120
           RILAALCQDYQGGTLAGDLCEDLCVAGELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEE
Sbjct: 61  RILAALCQDYQGGTLAGDLCEDLCVAGELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEE 120

Query: 121 AFSSFPPLSLLEEEAGEGGQDMPEAELLLMVAGEVKSALGLELSNSSLGPWWPGRRGPRW 180
           AFSSFPPLSLLEEEAGEGGQDMPEAELLLMVAGEVKSALGLELSNSSLGPWWPGRRGPRW
Sbjct: 121 AFSSFPPLSLLEEEAGEGGQDMPEAELLLMVAGEVKSALGLELSNSSLGPWWPGRRGPRW 180

Query: 181 RGQLASLWALLQQEEYVYFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDR 240
           RGQLASLWALLQQEEYVYFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDR
Sbjct: 181 RGQLASLWALLQQEEYVYFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDR 240

Query: 241 APGAPGGGQAKAISDIALSFLDMVNHFDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDM 300
           APGAPGGGQAKAISDIALSFLDMVNHFDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDM
Sbjct: 241 APGAPGGGQAKAISDIALSFLDMVNHFDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDM 300

Query: 301 AFFEPKMREILEQNCTGDEDCNFFDCFSRCDLRVNKCGAQRVNNNLQVICDKIFRHWFSA 360
           AFFEPKMREILEQNCTGDEDCNFFDCFSRCDLRVNKCGAQRVNNNLQVICDKIFRHWFSA
Sbjct: 301 AFFEPKMREILEQNCTGDEDCNFFDCFSRCDLRVNKCGAQRVNNNLQVICDKIFRHWFSA 360

Query: 361 PLKSSAVSFQLQLQLQEAVQECADPGVPSGNTRRAASSVFWKLRQLLQATLRELQEAEK 419
           PLKSSAVSFQLQLQLQEAVQECADPGVPSGNTRRAASSVFWKLRQLLQATLRELQEAEK
Sbjct: 361 PLKSSAVSFQLQLQLQEAVQECADPGVPSGNTRRAASSVFWKLRQLLQATLRELQEAEK 419


>gi|224922839 hypothetical protein LOC138311 [Homo sapiens]
          Length = 431

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 88/346 (25%), Positives = 143/346 (41%), Gaps = 31/346 (8%)

Query: 28  FAAWTAGWVLAAALLLRAHPGVLSERCTDEKSRRILAALCQDYQGGTLAGDLCEDLCVAG 87
           F AW    V A + L+  H    SERC     + ++   C  Y+ G ++G +C+DLC   
Sbjct: 33  FLAWLG--VFAGSWLVYVHYSSYSERCRGHVCQVVI---CDQYRKGIISGSVCQDLCELH 87

Query: 88  ELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEE------AFSSFPP---LSLLEEEA-GE 137
            + ++ CL    G++V    WR + V +K   E      A S   P   L L ++   G 
Sbjct: 88  MVEWRTCLSVAPGQQVYSGLWRDKDVTIKCGIEETLDSKARSDAAPRRELVLFDKPTRGT 147

Query: 138 GGQDMPEAELLLMVA--GEVKSALGLELSNSSLGPWWPGRRGPRWRGQLASLWALLQQEE 195
             ++  E  L  + A  G++ S   L      +  +    R      +  S+WALLQ+ E
Sbjct: 148 SIKEFREMTLSFLKANLGDLPSLPALVGQVLLMADFNKDNRVSL--AEAKSVWALLQRNE 205

Query: 196 YVYFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDR--APGAPGGGQAKAI 253
           ++    LQ+   H   +LG CG  Y  E +  G+ H  AL PL R   P A  G   + +
Sbjct: 206 FLLLLSLQE-KEHASRLLGYCGDLYLTEGVPHGAWHAAALPPLLRPLLPPALQGALQQWL 264

Query: 254 -------SDIALSFLDMVNHFDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDMAFFEPK 306
                  + IA+  L+ V           ++C+    N    + +     D+     E  
Sbjct: 265 GPAWPWRAKIAIGLLEFVEELFHGSYGTFYMCETTLANVGYTATYDFKMADLQQVAPEAT 324

Query: 307 MREILE-QNCTGDEDCNF-FDCFSRCDLRVNKCGAQRVNNNLQVIC 350
           +R  L+ + C    DC +  DC + CD  + +C    +  NL  +C
Sbjct: 325 VRRFLQGRRCEHSTDCTYGRDCRAPCDRLMRQCKGDLIQPNLAKVC 370


>gi|165932391 family with sequence similarity 69, member A [Homo
           sapiens]
          Length = 428

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 84/346 (24%), Positives = 138/346 (39%), Gaps = 31/346 (8%)

Query: 28  FAAWTAGWVLAAALLLRAHPGVLSERCTDEKSRRILAALCQDYQGGTLAGDLCEDLCVAG 87
           F +W    V   + ++       +E C  +  ++I+   C  Y+ G + G  C  LCV  
Sbjct: 30  FFSWLV--VFVGSWIIYVQYSTYTELCRGKDCKKII---CDKYKTGVIDGPACNSLCVTE 84

Query: 88  ELLFQRCLHYNRGKKVLQADWRGRPVVLKSKEEAFSSFPPLSLLEEEAGEGGQDMPEAEL 147
            L F +CL      ++    W   P V+K + E        + LE        D P    
Sbjct: 85  TLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGT 144

Query: 148 LL-----MVAGEVKSALG-----LELSNSSLGPWWPGRRGPRWRGQLASLWALLQQEEYV 197
            +     MV    K+ LG      EL N  L      + G    G+  S WALLQ  E++
Sbjct: 145 TVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEFL 204

Query: 198 YFSLLQDLSPHVLPVLGSCGHFYAVEFLAAGSPHHRALFPLDRAPGAPGGGQAK------ 251
              +LQD   H   ++G CG  Y +E +   S +  +L P       P G +        
Sbjct: 205 LMVILQD-KEHTPKLMGFCGDLYVMESVEYTSLYGISL-PWVIELFIPSGFRRSMDQLFT 262

Query: 252 ----AISDIALSFLDMVNH-FDSDFSHRLHLCDIKPENFAIRSDFTVVAIDVDMAFFEPK 306
                 + IA+  L+ V   F   + + L +CD   +N      + +  +D+     E  
Sbjct: 263 PSWPRKAKIAIGLLEFVEDVFHGPYGNFL-MCDTSAKNLGYNDKYDLKMVDMRKIVPETN 321

Query: 307 MREIL-EQNCTGDEDCNF-FDCFSRCDLRVNKCGAQRVNNNLQVIC 350
           ++E++ +++C  D DC +  DC + CD    KC ++ +  NL   C
Sbjct: 322 LKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKAC 367


>gi|197333863 hypothetical protein LOC205428 isoform b [Homo
           sapiens]
          Length = 221

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 24/185 (12%)

Query: 213 LGSCGHFYAVEFLAAGSPHHRALFPLDRAPGAPGGGQAKAISDIALSFLDMVNHFDSDFS 272
           LG+CG   AV ++         L+    AP       A  + +IA    +      +DF 
Sbjct: 24  LGACGRMVAVNYVG------EELWSYFNAPWEKRVDLAWQLMEIAEQLTN------NDFE 71

Query: 273 HRLHLCDIKPENFAI-RSDFTVVAIDVDMAFFEPK--MREILEQNCTGDEDCNFFDCFSR 329
             L+L D+  +NFA+   D  V+ +D +      K  +R+   +N     +  F DC   
Sbjct: 72  FALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKE 131

Query: 330 CDLRVNK---CGAQRVNNNLQVICDKIF-RH--WFSAP---LKSSAVSFQLQLQLQEAVQ 380
             L  +K   C    V++N   +C  +  RH  W       L           +L+  + 
Sbjct: 132 ACLSFSKEILCARATVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKDGRLEALLD 191

Query: 381 ECADP 385
           ECA+P
Sbjct: 192 ECANP 196


>gi|27734895 hypothetical protein LOC205428 isoform a [Homo sapiens]
          Length = 430

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 24/185 (12%)

Query: 213 LGSCGHFYAVEFLAAGSPHHRALFPLDRAPGAPGGGQAKAISDIALSFLDMVNHFDSDFS 272
           LG+CG   AV ++         L+    AP       A  + +IA    +      +DF 
Sbjct: 233 LGACGRMVAVNYVG------EELWSYFNAPWEKRVDLAWQLMEIAEQLTN------NDFE 280

Query: 273 HRLHLCDIKPENFAI-RSDFTVVAIDVDMAFFEPK--MREILEQNCTGDEDCNFFDCFSR 329
             L+L D+  +NFA+   D  V+ +D +      K  +R+   +N     +  F DC   
Sbjct: 281 FALYLLDVSFDNFAVGPRDGKVIIVDAENVLVADKRLIRQNKPENWDVWYESKFDDCDKE 340

Query: 330 CDLRVNK---CGAQRVNNNLQVICDKIF-RH--WFSAP---LKSSAVSFQLQLQLQEAVQ 380
             L  +K   C    V++N   +C  +  RH  W       L           +L+  + 
Sbjct: 341 ACLSFSKEILCARATVDHNYYAVCQNLLSRHATWRGTSGGLLHDPPSEIAKDGRLEALLD 400

Query: 381 ECADP 385
           ECA+P
Sbjct: 401 ECANP 405


>gi|27477111 step II splicing factor SLU7 [Homo sapiens]
          Length = 586

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 4/57 (7%)

Query: 97  YNRGKKV-LQADWRGRPVVLKS---KEEAFSSFPPLSLLEEEAGEGGQDMPEAELLL 149
           Y++G +V LQAD     ++ KS   K+E F      S+LE+  G+   D P AELLL
Sbjct: 335 YDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLL 391


>gi|4502735 cyclin-dependent kinase 4 [Homo sapiens]
          Length = 303

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 238 LDRAPGAPGGGQAKAISDIALSFLDMVNHFDSD-FSHRLHLCDIKPENFAIRSDFTVVAI 296
           LD+AP  P G  A+ I D+   FL  ++   ++   HR    D+KPEN  + S  TV   
Sbjct: 104 LDKAP--PPGLPAETIKDLMRQFLRGLDFLHANCIVHR----DLKPENILVTSGGTVKLA 157

Query: 297 DVDMA 301
           D  +A
Sbjct: 158 DFGLA 162


>gi|226423905 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 2 [Homo sapiens]
          Length = 267

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 16/58 (27%), Positives = 28/58 (48%)

Query: 135 AGEGGQDMPEAELLLMVAGEVKSALGLELSNSSLGPWWPGRRGPRWRGQLASLWALLQ 192
           AG  G+ +   E LL+V    +  LG  +  + LGP + G +G      ++++W   Q
Sbjct: 154 AGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQ 211


>gi|226423903 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 16/58 (27%), Positives = 28/58 (48%)

Query: 135 AGEGGQDMPEAELLLMVAGEVKSALGLELSNSSLGPWWPGRRGPRWRGQLASLWALLQ 192
           AG  G+ +   E LL+V    +  LG  +  + LGP + G +G      ++++W   Q
Sbjct: 154 AGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQ 211


>gi|14249178 splA/ryanodine receptor domain and SOCS box containing
           2 isoform 1 [Homo sapiens]
          Length = 263

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 16/58 (27%), Positives = 28/58 (48%)

Query: 135 AGEGGQDMPEAELLLMVAGEVKSALGLELSNSSLGPWWPGRRGPRWRGQLASLWALLQ 192
           AG  G+ +   E LL+V    +  LG  +  + LGP + G +G      ++++W   Q
Sbjct: 154 AGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQ 211


>gi|193804854 hypothetical protein LOC79742 isoform 1 [Homo sapiens]
          Length = 433

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 51/229 (22%), Positives = 80/229 (34%), Gaps = 23/229 (10%)

Query: 181 RGQLASLWALLQQEEYVYFSLLQDLSPHVLP-VLGSCGHFYAVEFLAAGSPHHRALFPLD 239
           R +L  L+ L      +   +        LP  LGSCG F     L + S       PL 
Sbjct: 205 RDKLRLLYTLAVNSHPILLQIFPGAEGWPLPKYLGSCGRF-----LVSTSTR-----PLQ 254

Query: 240 RAPGAPGGGQAKAISDIALSFLDMVNHFDS-DFSHRLHLCDIKPENFAIRSDFTVVAIDV 298
               AP    A    D+A   L ++    S D ++  +   I    F + ++  +   D 
Sbjct: 255 EFYDAPPDQAA----DLAYQLLGVLESLRSNDLNYFFYFTHIDAGMFGVFNNGHLFIRDA 310

Query: 299 DMAFFEPKMREILEQNCTGDEDCNFFDCF-SRCDLRVNKCGAQRVNNNLQVICDKIFRHW 357
                  K     E N  G E+ + F C  S C  ++  C +     +L ++C K+    
Sbjct: 311 SAVGVIDKQEGSQEANRAG-ENKDIFSCLVSGCQAQLPSCESISEKQSLVLVCQKLLPRL 369

Query: 358 FSAPLKSSAVSFQLQLQLQEAVQECADPGVPSGNTRRAASSVFWKLRQL 406
                 S      +Q  +   + +C D   P      AAS +   LR L
Sbjct: 370 LQGRFPS-----PVQDDIDSILVQCGDSIRPDPEVLGAASQLKDILRPL 413


>gi|28557802 sterile alpha motif domain containing 14 [Homo sapiens]
          Length = 445

 Score = 29.3 bits (64), Expect = 7.0
 Identities = 12/21 (57%), Positives = 13/21 (61%)

Query: 228 GSPHHRALFPLDRAPGAPGGG 248
           GSP HR   PL   PG+P GG
Sbjct: 76  GSPLHRLRSPLHSGPGSPAGG 96


>gi|23592242 vestigial-like 2 isoform 2 [Homo sapiens]
          Length = 143

 Score = 28.9 bits (63), Expect = 9.1
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 18/112 (16%)

Query: 92  QRCLHYNRGKKVLQADWRGRPVVLKSKEEAFSSFPPLSLLEEEAGEGGQDMPEAE----- 146
           Q+  +Y++ ++  + +    P    S   +FSS  P S+ EEE     +  PEAE     
Sbjct: 27  QKLAYYSKMQEAQECN--ASPSSSGSGSSSFSSQTPASIKEEEGSPEKERPPEAEYINSR 84

Query: 147 --LLLMVAGEVKSALGLELSN-----SSLGPWWPGRRGPR----WRGQLASL 187
             L     G++ S +    S      SS  P     + PR    WR +  SL
Sbjct: 85  CVLFTYFQGDISSVVDEHFSRALSQPSSYSPSCTSSKAPRSSGPWRARRYSL 136


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,392,888
Number of Sequences: 37866
Number of extensions: 816903
Number of successful extensions: 2173
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2161
Number of HSP's gapped (non-prelim): 15
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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