Search of human proteins with 194239709

Search of human proteins with 194239709

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194239709 dedicator of cytokinesis 9 isoform d [Homo
sapiens]
         (1253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]     2526   0.0  
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]     2482   0.0  
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]     2444   0.0  
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]      2401   0.0  
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]              1380   0.0  
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]              1219   0.0  
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]                364   e-100
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]                273   8e-73
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]                 263   1e-69
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]                  46   3e-04
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]                   46   3e-04
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...    46   3e-04
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...    46   3e-04
gi|55741447 pleckstrin homology domain containing, family H (wit...    45   6e-04
gi|217416392 pleckstrin homology domain containing, family H (wi...    44   7e-04
gi|187608516 centaurin, beta 2 [Homo sapiens]                          42   0.003
gi|24432056 hypothetical protein LOC144717 [Homo sapiens]              42   0.004
gi|5031805 insulin receptor substrate 1 [Homo sapiens]                 41   0.008
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]                 41   0.008
gi|238908495 similar to pleckstrin homology domain protein (5V32...    40   0.011
gi|219689123 pleckstrin homology domain containing, family A mem...    40   0.011
gi|19923493 pleckstrin homology domain containing, family A memb...    40   0.011
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]                  40   0.018
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H...    40   0.018
gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H...    40   0.018
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]                  39   0.024
gi|7661880 centaurin beta1 [Homo sapiens]                              39   0.024
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa...    39   0.031
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]           39   0.041
gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]      37   0.091

>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
          Length = 1253

 Score = 2526 bits (6547), Expect = 0.0
 Identities = 1253/1253 (100%), Positives = 1253/1253 (100%)

Query: 1    MQADKCRTSSRSVKKELVIESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQK 60
            MQADKCRTSSRSVKKELVIESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQK
Sbjct: 1    MQADKCRTSSRSVKKELVIESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQK 60

Query: 61   KTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDW 120
            KTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDW
Sbjct: 61   KTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDW 120

Query: 121  HLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWL 180
            HLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWL
Sbjct: 121  HLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWL 180

Query: 181  YKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQN 240
            YKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQN
Sbjct: 181  YKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQN 240

Query: 241  NKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDE 300
            NKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDE
Sbjct: 241  NKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDE 300

Query: 301  QSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFE 360
            QSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFE
Sbjct: 301  QSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFE 360

Query: 361  EKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLN 420
            EKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLN
Sbjct: 361  EKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLN 420

Query: 421  HFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEK 480
            HFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEK
Sbjct: 421  HFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEK 480

Query: 481  VLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLD 540
            VLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLD
Sbjct: 481  VLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLD 540

Query: 541  KNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVN 600
            KNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVN
Sbjct: 541  KNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVN 600

Query: 601  SSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKA 660
            SSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKA
Sbjct: 601  SSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKA 660

Query: 661  RNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQ 720
            RNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQ
Sbjct: 661  RNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQ 720

Query: 721  LHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANL 780
            LHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANL
Sbjct: 721  LHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANL 780

Query: 781  PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 840
            PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG
Sbjct: 781  PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 840

Query: 841  AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQ 900
            AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQ
Sbjct: 841  AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQ 900

Query: 901  CHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSW 960
            CHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSW
Sbjct: 901  CHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSW 960

Query: 961  FFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKN 1020
            FFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKN
Sbjct: 961  FFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKN 1020

Query: 1021 ANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPL 1080
            ANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPL
Sbjct: 1021 ANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPL 1080

Query: 1081 NLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLK 1140
            NLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLK
Sbjct: 1081 NLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLK 1140

Query: 1141 NLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESL 1200
            NLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESL
Sbjct: 1141 NLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESL 1200

Query: 1201 ALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ 1253
            ALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ
Sbjct: 1201 ALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ 1253


>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
          Length = 2068

 Score = 2482 bits (6434), Expect = 0.0
 Identities = 1232/1234 (99%), Positives = 1233/1234 (99%)

Query: 1    MQADKCRTSSRSVKKELVIESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQK 60
            MQADKCRTSSRSVKKELVIESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQK
Sbjct: 1    MQADKCRTSSRSVKKELVIESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQK 60

Query: 61   KTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDW 120
            KTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDW
Sbjct: 61   KTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDW 120

Query: 121  HLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWL 180
            HLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWL
Sbjct: 121  HLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWL 180

Query: 181  YKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQN 240
            YKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQN
Sbjct: 181  YKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQN 240

Query: 241  NKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDE 300
            NKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDE
Sbjct: 241  NKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDE 300

Query: 301  QSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFE 360
            QSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFE
Sbjct: 301  QSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFE 360

Query: 361  EKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLN 420
            EKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLN
Sbjct: 361  EKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLN 420

Query: 421  HFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEK 480
            HFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEK
Sbjct: 421  HFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEK 480

Query: 481  VLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLD 540
            VLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLD
Sbjct: 481  VLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLD 540

Query: 541  KNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVN 600
            KNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVN
Sbjct: 541  KNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVN 600

Query: 601  SSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKA 660
            SSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKA
Sbjct: 601  SSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKA 660

Query: 661  RNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQ 720
            RNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQ
Sbjct: 661  RNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQ 720

Query: 721  LHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANL 780
            LHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANL
Sbjct: 721  LHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANL 780

Query: 781  PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 840
            PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG
Sbjct: 781  PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 840

Query: 841  AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQ 900
            AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQ
Sbjct: 841  AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQ 900

Query: 901  CHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSW 960
            CHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSW
Sbjct: 901  CHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSW 960

Query: 961  FFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKN 1020
            FFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKN
Sbjct: 961  FFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKN 1020

Query: 1021 ANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPL 1080
            ANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPL
Sbjct: 1021 ANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPL 1080

Query: 1081 NLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLK 1140
            NLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLK
Sbjct: 1081 NLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLK 1140

Query: 1141 NLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESL 1200
            NLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESL
Sbjct: 1141 NLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESL 1200

Query: 1201 ALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1234
            ALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI +
Sbjct: 1201 ALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1234


>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
          Length = 1254

 Score = 2444 bits (6335), Expect = 0.0
 Identities = 1211/1211 (100%), Positives = 1211/1211 (100%)

Query: 43   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102
            AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE
Sbjct: 44   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103

Query: 103  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162
            EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE
Sbjct: 104  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163

Query: 163  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222
            DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS
Sbjct: 164  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223

Query: 223  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282
            KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN
Sbjct: 224  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283

Query: 283  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342
            FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP
Sbjct: 284  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343

Query: 343  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402
            DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL
Sbjct: 344  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403

Query: 403  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462
            FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI
Sbjct: 404  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463

Query: 463  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522
            FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM
Sbjct: 464  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523

Query: 523  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582
            PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG
Sbjct: 524  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583

Query: 583  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642
            NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL
Sbjct: 584  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643

Query: 643  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702
            YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH
Sbjct: 644  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703

Query: 703  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762
            HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL
Sbjct: 704  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763

Query: 763  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822
            KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT
Sbjct: 764  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823

Query: 823  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882
            QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT
Sbjct: 824  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883

Query: 883  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942
            QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI
Sbjct: 884  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943

Query: 943  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002
            LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM
Sbjct: 944  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003

Query: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062
            LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE
Sbjct: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063

Query: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122
            YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG
Sbjct: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123

Query: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182
            TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR
Sbjct: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183

Query: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL 1242
            DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL
Sbjct: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL 1243

Query: 1243 STITLKVSWSQ 1253
            STITLKVSWSQ
Sbjct: 1244 STITLKVSWSQ 1254


>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
          Length = 2069

 Score = 2401 bits (6222), Expect = 0.0
 Identities = 1190/1192 (99%), Positives = 1191/1192 (99%)

Query: 43   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102
            AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE
Sbjct: 44   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103

Query: 103  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162
            EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE
Sbjct: 104  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163

Query: 163  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222
            DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS
Sbjct: 164  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223

Query: 223  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282
            KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN
Sbjct: 224  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283

Query: 283  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342
            FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP
Sbjct: 284  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343

Query: 343  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402
            DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL
Sbjct: 344  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403

Query: 403  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462
            FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI
Sbjct: 404  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463

Query: 463  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522
            FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM
Sbjct: 464  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523

Query: 523  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582
            PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG
Sbjct: 524  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583

Query: 583  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642
            NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL
Sbjct: 584  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643

Query: 643  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702
            YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH
Sbjct: 644  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703

Query: 703  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762
            HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL
Sbjct: 704  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763

Query: 763  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822
            KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT
Sbjct: 764  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823

Query: 823  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882
            QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT
Sbjct: 824  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883

Query: 883  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942
            QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI
Sbjct: 884  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943

Query: 943  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002
            LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM
Sbjct: 944  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003

Query: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062
            LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE
Sbjct: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063

Query: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122
            YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG
Sbjct: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123

Query: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182
            TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR
Sbjct: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183

Query: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1234
            DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI +
Sbjct: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1235


>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
          Length = 2073

 Score = 1380 bits (3571), Expect = 0.0
 Identities = 682/1177 (57%), Positives = 885/1177 (75%), Gaps = 14/1177 (1%)

Query: 19   IESPLQYKDAAQGEVEAESPGPVPAKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYD 78
            +  P    +  Q   EA     V  K K++EPLDYENVI Q+KTQI +D LR++L+FP +
Sbjct: 11   LSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPME 70

Query: 79   DFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLP 138
            D   +++ RQ R + STVP  AE+ AQSLFV ECIKTY++DWH+VNYKYED+SG+FR LP
Sbjct: 71   DISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLP 130

Query: 139  NKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKR 198
             K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I+VTM+ FKR
Sbjct: 131  CKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKR 190

Query: 199  RFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSY 258
            R+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ  K+RR AFELKM DK S+
Sbjct: 191  RYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSH 250

Query: 259  LLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLEGSGSGLD-S 313
             LAA++E EMEEW+  L KI+Q+N ++ +QEK+   ++ +DDE   Q K E   + L+ S
Sbjct: 251  YLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERS 310

Query: 314  YLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVK 370
              PEL K  RE E   K    + R  LF  D + Q+LDFS  EP++K FEEK  KR LV 
Sbjct: 311  MHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVN 370

Query: 371  CNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLAT 430
            C+DL+FN+   + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN  SVR+ML  
Sbjct: 371  CHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWG 430

Query: 431  TSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSIT 487
            +S  L +      S  +  +H   E+ ++Y +QGIFSVT PHP+IFLVARIEKVLQG+IT
Sbjct: 431  SSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNIT 490

Query: 488  HCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSA 547
            HCAEPY+K+SD  K AQKV + AKQ C RLGQYRMPFAWAAR +FKD  G+LD + RFS 
Sbjct: 491  HCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSP 550

Query: 548  IYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTK 607
            +Y+QDS+KLS++D+LKLL++++KPEK  KL +I G L+IT++ V  D  N + SSY+P K
Sbjct: 551  LYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNCITSSYVPLK 609

Query: 608  QFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICI 667
             FE   +  IT EVEEFVP + K+  P+TIY NHLYVYP  LKYDSQK+FAKARNIA+C+
Sbjct: 610  PFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCV 668

Query: 668  EFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHL 727
            EF+DSDE D+  LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP  LH+KHHL
Sbjct: 669  EFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHL 728

Query: 728  LLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGY 787
            L TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSANLP GYL  
Sbjct: 729  LFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNL 788

Query: 788  QELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNE 847
             +    R    +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ  +SG++ +  E
Sbjct: 789  NDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGE 848

Query: 848  LVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHVVAQCHEEGL 906
            L+KYLK LHAME  VMI FLP IL QLFRVLT  T E+ V +N T V++H+V++CHEEGL
Sbjct: 849  LIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGL 908

Query: 907  ESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVL 966
            +S+LRS++KY+++ E   A + + +HE L  +M  ILK SADFL+ NKLLKYSWFFF+++
Sbjct: 909  DSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEII 968

Query: 967  IKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLA 1026
             KSMA +L+E +K+KL R QRFP +YHH + +++  ++PH+T ++ + P+ S+N N+SLA
Sbjct: 969  AKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLA 1028

Query: 1027 VFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLPMPF 1086
             F+KRC T MDRGF+F  IN+YIS F+P DPK L EYKFEFL+ +CNHEHYIPLNLPM F
Sbjct: 1029 SFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAF 1088

Query: 1087 GKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKH 1146
             K ++QR QD  L+YSL+DE+C++HFLVGLLLRE   ALQ+  E+R  AISV+KNLLIKH
Sbjct: 1089 AKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKH 1148

Query: 1147 SFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRD 1183
            +FD RY  ++ QA+IA LYLP  GLL+EN+QR+  RD
Sbjct: 1149 AFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRD 1185


>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
          Length = 2186

 Score = 1219 bits (3153), Expect = 0.0
 Identities = 622/1242 (50%), Positives = 872/1242 (70%), Gaps = 53/1242 (4%)

Query: 44   KPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEE 103
            KP+L+EPLDYE VI + +    ND L+++L FP DDF  A +    R + STVP  AE +
Sbjct: 44   KPRLLEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHK 103

Query: 104  AQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDE 162
            A++L V E  K Y+S WH+VNYKYE YSG+ RQLP    K +KLP H +E+D E+ DKDE
Sbjct: 104  AENLLVKEACKFYSSQWHVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDE 163

Query: 163  DAASLGSQKGG-------ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNL 213
            D  S  S KGG       + K GWLYKGN NS ++  VT+RSFK+R+F L QL D SY +
Sbjct: 164  DTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIM 223

Query: 214  NFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWIT 273
            NFYKDEKISKEPKG IFLDSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI 
Sbjct: 224  NFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIH 283

Query: 274  ILNKILQLNFEAAMQEKRNG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSARE 324
             LN+ILQ++ E  +Q +R+        DS ++    +   E + S  ++   + AK   E
Sbjct: 284  TLNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTE 343

Query: 325  AEIKLKSE---SRVKLFYLDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSF 376
             E  +K+     R+ LF LDPD      QK D    E  +K FEEK  KRI++ C  L+ 
Sbjct: 344  TEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNS 403

Query: 377  NLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALM 436
            NLQ CV ENE  P TN+EPFFV+++L+D++ +RKISADFHVDLNH +VRQML   S AL 
Sbjct: 404  NLQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALE 463

Query: 437  NGS--------GQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITH 488
            NG+         + P + KG L E  +++PKQ +FSV+ PH +I LVA+IEKVL G+I  
Sbjct: 464  NGNIDTITPRQSEEPHI-KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIAS 521

Query: 489  CAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAI 548
             AEPY+K+ DS+K AQK+LK+ +Q C +LG+YRMPFAWA R++FKD  GN+D+++RFS +
Sbjct: 522  GAEPYIKNPDSNKYAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPL 581

Query: 549  YRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQ 608
            +RQ+S+K+S +D++KL++D+R+ ++++K+  I G+LDI +DNV  + PN V SS+IP K 
Sbjct: 582  FRQESSKISTEDLVKLVSDYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKP 641

Query: 609  FETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIE 668
            F   ++T  T EVEEFV    K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIE
Sbjct: 642  FNMMAQTEPTVEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIE 701

Query: 669  FKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLL 728
            FK+SDEE ++PLKCIYG+PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L
Sbjct: 702  FKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHIL 761

Query: 729  LTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQ 788
             +F+HV+CD ++K + KK++ +ET VGY+WLPL+K  ++ + E +IP++ +LP  YL +Q
Sbjct: 762  FSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQ 821

Query: 789  ELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNE 847
            +   G+H G +IKWVDGGKPL K+ST +VSTV TQD H++ FFQ CQK E   +Q+  + 
Sbjct: 822  DSASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSN 881

Query: 848  LVKYLKSLHAMEG-HVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGL 906
             ++  K+L  +E  H +++FLP ILNQLF+VL +  ++E+   VTRV+  +VA+CHEE L
Sbjct: 882  FIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQL 941

Query: 907  ESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVL 966
            +  ++SY+K+ +K     A + +TVHEEL K++T +LK S D  T   +LK+SWFFF ++
Sbjct: 942  DHSVQSYIKFVFKTR---ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAII 997

Query: 967  IKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLA 1026
            +KSMAQHLI+ +K++L R QRFP SY + ++ +V +L  H+  K++D  E ++ ANHS+A
Sbjct: 998  LKSMAQHLIDTNKIQLPRPQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVA 1057

Query: 1027 VFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP--- 1083
             F+KRCFTFMDRG+VFK +NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP   
Sbjct: 1058 RFLKRCFTFMDRGYVFKMVNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRS 1117

Query: 1084 --MPFGKGRIQRYQDLQL----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1137
              +P      +  Q+L      +YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++
Sbjct: 1118 ANIPDPLTPSESTQELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALA 1177

Query: 1138 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVK 1196
            VLKNL+ KHSFDDRY     QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN +    +
Sbjct: 1178 VLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSR 1237

Query: 1197 DESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCS 1238
            D+             +  +++D S  KD+L +I+   +   S
Sbjct: 1238 DDLSTNGGFQSQTAIKHANSVDTSFSKDVLNSIAAFSSIAIS 1279


>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
          Length = 2047

 Score =  364 bits (934), Expect = e-100
 Identities = 304/1061 (28%), Positives = 473/1061 (44%), Gaps = 211/1061 (19%)

Query: 284  EAAMQEKRNGDSHEDDEQSKLEGSGSGL-----DSYLPELAKSAREAEIKLKSES----- 333
            E +   +R   S ED  +S    S   L     DS LP L + A   ++  ++E+     
Sbjct: 167  EDSNDSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQH 226

Query: 334  ---RVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPT 390
                +   Y  PD  +     + PE     E FG+RILVKC  L F ++           
Sbjct: 227  RPPALLTLYPAPDEDEAVERCSRPEPP--REHFGQRILVKCLSLKFEIE----------- 273

Query: 391  TNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGIL 450
              +EP F  L+L+D++  +KIS +F+ DLN  S++ +L                      
Sbjct: 274  --IEPIFGILALYDVREKKKISENFYFDLNSDSMKGLLRAHGT----------------- 314

Query: 451  HEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPYM--KSSDSSKVAQKVL 507
            H A     +  IFSVT P PDIFLV ++EKVLQ G I+ C EPYM  K  D++K  +K+ 
Sbjct: 315  HPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLE 374

Query: 508  K---NAKQACQRLGQYRMPFAWAARTLFK--DASGNLDKNA------------------- 543
            K    A+Q C RLG+YRMPFAW A  L     ++G LD+++                   
Sbjct: 375  KLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQ 434

Query: 544  ----------RFSAI----------YRQDSNKLSNDDMLKLLADFRKPEKMAK-LPVILG 582
                       FS            ++Q++ +LS++D+ K LAD R+P  + + L  +  
Sbjct: 435  DRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTA 494

Query: 583  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642
             L I I     +    ++   +  K +      P T E+ EF P    +  P+T Y N L
Sbjct: 495  QLKIDISPAPENPHFCLSPELLHIKPYPDPRGRP-TKEILEF-PAREVYA-PHTSYRNLL 551

Query: 643  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702
            YVYP  L + S++     RN+A+ +++  + E+ SQ L  I+G+     FTR AF  V++
Sbjct: 552  YVYPHSLNFSSRQG--SVRNLAVRVQYM-TGEDPSQALPVIFGKSSCSEFTREAFTPVVY 608

Query: 703  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762
            H+++PEFY+E K+ LP  + E HHLL TF+HVSC        +    +ET VG++W+PLL
Sbjct: 609  HNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSC------QPRPGTALETPVGFTWIPLL 662

Query: 763  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822
            + GR+ T    +PVS + P          +     P ++WVDG K +  +    VS+V+ 
Sbjct: 663  QHGRLRTGPFCLPVSVDQPPPSYSVLTPDVAL---PGMRWVDGHKGVFSVELTAVSSVHP 719

Query: 823  QDQHLHNFFQYCQKTESGA---------QALGN---ELVKYLKSLHAMEGHVMIAFLPTI 870
            QD +L  FF      E GA          + GN   EL   L +L       ++AF   +
Sbjct: 720  QDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHV 779

Query: 871  LNQLFRVLTR-ATQEEVAVNVTR----VIIHVVAQCHE--------EGLESHLRSYVKYA 917
            L++L R++ R        VN+ R     + HVV+  H          G    L +YV YA
Sbjct: 780  LDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYA 839

Query: 918  YK----------AEPYVASEYKTVHEELTKSMTTILKPSADFLTSN-------------- 953
            ++            P V  +  T+     +  +  L  S    +SN              
Sbjct: 840  FRLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEV 899

Query: 954  --------------------------KLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQR 987
                                       +L+++WFFF +++KSMA HL+   ++   R  R
Sbjct: 900  SRILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLR 959

Query: 988  FPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINN 1047
            FP  +   +  +V  +   +  +   + E +++ N SLA F+    + +DRGFVF  +  
Sbjct: 960  FPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRA 1019

Query: 1048 YISCFA-----PGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-------------MPFGKG 1089
            +    A       +P  L   + EF R++C+HEHY+ LNLP             +     
Sbjct: 1020 HYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTS 1079

Query: 1090 RIQRYQDLQLD------YSLTDEFCRNHFLVGLLLREVGTALQEFREVRLI----AISVL 1139
            +   +     D      + L+  F + HFL GLLL E+  AL+   E   +    AIS +
Sbjct: 1080 QSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAV 1139

Query: 1140 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRIN 1180
             +LL  H  D RYA  + +AR+A LYLPL  +  + + R++
Sbjct: 1140 HSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLH 1180



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 30/117 (25%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 46  KLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQ 105
           +++EPLD+E+V++ +        LR+++ FP DD +  +  R+ R   +T P   ++E  
Sbjct: 49  EVVEPLDFEDVLLSRPPDAEPGPLRDLVEFPADDLELLLQPRECR---TTEPGIPKDEKL 105

Query: 106 SLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDK--LPVHVYEVDEEVDK 160
              V   ++ Y  DW +V+ +Y+  S  +  +     +  +  LP  V+E D   D+
Sbjct: 106 DAQVRAAVEMYIEDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDE 162


>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
          Length = 2099

 Score =  273 bits (698), Expect = 8e-73
 Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%)

Query: 323 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 382
           ++ E   ++  + +LF L P   + D     P  +  +E  G RILVK   L F ++   
Sbjct: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280

Query: 383 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 442
                     +EP F +++L+D+K  +KIS +FH DLN    +  L   +P++       
Sbjct: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323

Query: 443 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 499
                     AA    +  +FSVT P  DI+LV +IEKVLQ G I  CAEPY  +K SD 
Sbjct: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373

Query: 500 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 528
            K  +K+ K   QA   CQRLG+YRMPFAWA                             
Sbjct: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433

Query: 529 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 570
              RTL       + + +L++N             S+ ++Q+ ++LS++D+ K LAD+++
Sbjct: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493

Query: 571 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 629
              + + +  I G L + I          +    +P K F   ++T    E+ EF P   
Sbjct: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551

Query: 630 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 689
            +  P+T+Y N LYVYP+ L + ++   A ARNI I I+F    E+ S  +  I+G+  G
Sbjct: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607

Query: 690 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 749
           P F +  + AV +H+++P+FY+E+KI+LP +L   HHLL TF+H+SC      S      
Sbjct: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661

Query: 750 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 808
           VET +GYSWLP+L + R+ T    +PV+   LP  Y  +    +     P IKW +G K 
Sbjct: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720

Query: 809 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 855
           +  I    VS+V+TQD HL  FF  C   ES                AL +EL   +  L
Sbjct: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780

Query: 856 HAMEGHVMIAFLPTILNQLFRV 877
           ++     ++ FL  +L++LF++
Sbjct: 781 NSSRLEPLVLFLHLVLDKLFQL 802



 Score =  138 bits (348), Expect = 3e-32
 Identities = 94/286 (32%), Positives = 143/286 (50%), Gaps = 32/286 (11%)

Query: 920  AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 979
            A P  AS+ K  HEEL   M       +  +    + KY+WFFF++L+KSMAQH+    K
Sbjct: 950  AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003

Query: 980  VKLLRNQRFPASYHHAVETVVNMLMPHITQ---KFRDNPEASKNANHSLAVFIKRCFTFM 1036
                R  RF   +   + T+VN++   I     K +   E ++  N SLA F+    + M
Sbjct: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLM 1063

Query: 1037 DRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL-----------P 1083
            DRGFVF  I +Y S  +    +  TL   + EFLR++C+HEHY+ LNL           P
Sbjct: 1064 DRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSP 1123

Query: 1084 MPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVRL 1133
             P            +QD ++   + LT E+ + HFL GLL  E+  AL    +   +V+ 
Sbjct: 1124 CPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQR 1183

Query: 1134 IAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRI 1179
             A+S + +LL  H  D R      + +IA LYLPL G++++ + ++
Sbjct: 1184 KAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQL 1229



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 11/126 (8%)

Query: 48  IEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL 107
           +EP+D+E +++     +     +E+  F  DD       ++    C T+     EE   L
Sbjct: 59  VEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVEL 114

Query: 108 --FVTECIKTYNSDWHLVNYKYE---DYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162
              V +C++TY  +W +VN K +   +  G F++  ++      LP   +E  E ++  E
Sbjct: 115 DPHVRDCVQTYIREWLIVNRKNQGSPEICG-FKKTGSRKDFHKTLPKQTFE-SETLECSE 172

Query: 163 DAASLG 168
            AA  G
Sbjct: 173 PAAQAG 178


>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
          Length = 2109

 Score =  263 bits (671), Expect = 1e-69
 Identities = 206/698 (29%), Positives = 338/698 (48%), Gaps = 137/698 (19%)

Query: 312 DSYLPELAKSAREAEI------KLKSESRVKLFYL--DPDAQKLDFSSAEPEVKSFEEKF 363
           D+ LP L       EI      + KS    +LF L   PD ++     + P++   +E F
Sbjct: 204 DALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDIP--KEHF 261

Query: 364 GKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFS 423
           G+R+LVKC  L F ++             +EP F +L+L+D+K  +KIS +F+ DLN   
Sbjct: 262 GQRLLVKCLSLKFEIE-------------IEPIFASLALYDVKEKKKISENFYFDLNSEQ 308

Query: 424 VRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ 483
           ++ +L    P         P+ +  +   A        IFS+T P  D+FLV ++EKVLQ
Sbjct: 309 MKGLLRPHVP---------PAAITTLARSA--------IFSITYPSQDVFLVIKLEKVLQ 351

Query: 484 -GSITHCAEPYM--KSSDSSKVAQKVLK---NAKQACQRLGQYRMPFAWAARTLFK--DA 535
            G I  CAEPYM  K +D++K  +K+ K    A Q CQRLG+YRMPFAW A  L     +
Sbjct: 352 QGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSS 411

Query: 536 SGNLDKNA-----------------RFSAI------------------------------ 548
           +G+L++++                 R S+I                              
Sbjct: 412 AGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTN 471

Query: 549 -YRQDSNKLSNDDMLKLLADFRKPEK-MAKLPVILGNLDITIDNVSSDFPNYVNSSYIPT 606
            ++Q+ ++LS++D+ K LAD R+P   + +L  I   L I I     + P+Y  +  +  
Sbjct: 472 FFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPEN-PHYCLTPELLQ 530

Query: 607 KQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAIC 666
            +    S+   T E+ EF P    +  P T Y N LY+YP+ L + +++    ARNI + 
Sbjct: 531 VKLYPDSRVRPTREILEF-PARDVYV-PNTTYRNLLYIYPQSLNFANRQG--SARNITVK 586

Query: 667 IEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHH 726
           ++F    E+ S  +  I+G+     F++ A+ AV++H+++P+F++EIK++LP  L + HH
Sbjct: 587 VQFMYG-EDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHH 645

Query: 727 LLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLG 786
           LL TF+HVSC        K+   +ET VGY+W+P+L++GR+ T +  +PVS   P     
Sbjct: 646 LLFTFYHVSCQQ------KQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPP--QA 697

Query: 787 YQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG------ 840
           Y  L       P +KWVD  K +  +    VS+++TQD +L  FF      +        
Sbjct: 698 YSVLSPEVPL-PGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHLFPVRI 756

Query: 841 ------AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTR-------------A 881
                    L NEL   + +L++ +   ++ FL  +L++L  ++ R             A
Sbjct: 757 GDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQA 816

Query: 882 TQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 919
           + E +A  + R+  ++     + G  S L SY+ Y ++
Sbjct: 817 SFEAMASIINRLHKNLEGNHDQHGRNSLLASYIHYVFR 854



 Score =  136 bits (343), Expect = 1e-31
 Identities = 80/254 (31%), Positives = 132/254 (51%), Gaps = 32/254 (12%)

Query: 956  LKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNP 1015
            L+ +WFFF++++KSM  HL  N K++  R  RFP  +   +  +V+ +   I  +F+ + 
Sbjct: 974  LQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPERFMDDIAALVSTIASDIVSRFQKDT 1033

Query: 1016 EASKNANHSLAVFIKRCFTFMDRGFVF-------KQINNYISCFAPGDPKTLFEYKFEFL 1068
            E  +  N SLA F+    + MDRGFVF       KQ+++ +  ++  +P  L   + +FL
Sbjct: 1034 EMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSSKL--YSLPNPSVLVSLRLDFL 1091

Query: 1069 RVVCNHEHYIPLNLPMPF-----------------GKGRIQRYQDLQLD--YSLTDEFCR 1109
            R++C+HEHY+ LNLP                      G     QD ++   + L+  F +
Sbjct: 1092 RIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQ 1151

Query: 1110 NHFLVGLLLREVGTALQEFRE----VRLIAISVLKNLLIKHSFDDRYASRSHQARIATLY 1165
             H+L GL+L E+   L    E    +    I+++ NLL  H  D RY+    +AR+A LY
Sbjct: 1152 QHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLY 1211

Query: 1166 LPLFGLLIENVQRI 1179
            LPL G+++E V ++
Sbjct: 1212 LPLIGIIMETVPQL 1225



 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 45/162 (27%), Positives = 73/162 (45%), Gaps = 20/162 (12%)

Query: 10  SRSVKKELVIESPLQYKDAAQ--------GEVEAESPGPVPAKPKLIEPLDYENVIVQKK 61
           SR+V  E+  +   QY  + Q        G +   +  P+    + ++P+D E+ ++   
Sbjct: 12  SRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLT---EAVDPVDLEDYLITHP 68

Query: 62  TQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWH 121
             + +  LR+++ FP DD +     R  R + S VP   EE      V +CI++Y  DW 
Sbjct: 69  LAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVP---EESEMDPHVRDCIRSYTEDWA 125

Query: 122 LVNYKYEDYSGEFRQLPNKVVKLDK----LPVHVYEVDEEVD 159
           +V  KY      F   PN + K  +    LP  V+E DE  D
Sbjct: 126 IVIRKYHKLGTGFN--PNTLDKQKERQKGLPKQVFESDEAPD 165


>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
          Length = 1966

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 55/248 (22%), Positives = 102/248 (41%), Gaps = 31/248 (12%)

Query: 660 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 719
           ARN+ + +   DS     Q LK       G        + VL+H+ +P + + +K+ +P 
Sbjct: 421 ARNVEVTMFIVDSS---GQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477

Query: 720 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL-KDGRVVTSEQHIPV-- 776
                 H+   F H  C    KG  K         G+S++PL+ +DGR +    H  +  
Sbjct: 478 DKFRGAHIRFEFRH--CSTKEKGEKK-------LFGFSFVPLMQEDGRTLPDGTHELIVH 528

Query: 777 ----SANL--PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNF 830
               + NL   + YL       G   G   + +   K    I++ L ST  TQ+  + + 
Sbjct: 529 KCEENTNLQDTTRYLKL-PFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDL 587

Query: 831 FQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNV 890
            ++        +   +++   L  L  ++G  ++ FL   L+ LF +L   +Q +    V
Sbjct: 588 LKW--------RTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDENSQ-KYGSKV 638

Query: 891 TRVIIHVV 898
              ++H++
Sbjct: 639 FDSLVHII 646


>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
          Length = 1865

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 75/342 (21%), Positives = 146/342 (42%), Gaps = 43/342 (12%)

Query: 644 VYPKYLKYDSQK-SFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702
           +Y   ++ D  K S   A+N+ + +   D   ED + L+ +   PG      S + +V++
Sbjct: 428 IYVTLVQGDFDKGSKTTAKNVEVTVSVYD---EDGKRLEHVIF-PGAGDEAISEYKSVIY 483

Query: 703 HH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPL 761
           +  + P +++ +K+ +P +   + HL  TF H S  +S   S K   +   ++       
Sbjct: 484 YQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTT 543

Query: 762 LKDGR----VVTSE----QHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDG---GKPLL 810
           L+DG     V  +E    +      +LPS     +E G     G  ++ +      K   
Sbjct: 544 LRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSA-TGKSMQSLGSCTISKDSF 602

Query: 811 KISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTI 870
           +IST + ST  TQ+  L    ++   T        + L + L+ L  ++G  ++ FL   
Sbjct: 603 QISTLVCSTKLTQNVDLLGLLKWRSNT--------SLLQQNLRQLMKVDGGEVVKFLQDT 654

Query: 871 LNQLFRVLTRATQEE----VAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKA------ 920
           L+ LF ++   ++ E    +  +    II ++A    +     L +Y+K  + A      
Sbjct: 655 LDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTK 714

Query: 921 -----EPYV-ASEYKTVHEELTKSMTTILKPSADFLTSNKLL 956
                + YV  +E   V+E+L K+M   L+    F+  +++L
Sbjct: 715 LTKVLKNYVDGAEKPGVNEQLYKAMKA-LESIFKFIVRSRIL 755


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
           sapiens]
          Length = 645

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%)

Query: 176 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 235
           K GWL K          ++++++R+F L      +  L +YKDE+ +K P+G ++L  C 
Sbjct: 49  KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 96

Query: 236 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 278
              +  N  +  +F FE+           + SY+L A S+ EMEEW+  L ++
Sbjct: 97  IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 149


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
           sapiens]
          Length = 638

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%)

Query: 176 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 235
           K GWL K          ++++++R+F L      +  L +YKDE+ +K P+G ++L  C 
Sbjct: 42  KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 89

Query: 236 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 278
              +  N  +  +F FE+           + SY+L A S+ EMEEW+  L ++
Sbjct: 90  IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 142


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 17/120 (14%)

Query: 163 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEK-I 221
           D   LG +   + K G+L K  M S +    +++KRR+F L Q       + +YK    +
Sbjct: 570 DGLGLGGES--LEKSGYLLK--MGSQV----KTWKRRWFVLRQ-----GQIMYYKSPSDV 616

Query: 222 SKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQL 281
            ++P+G + L+S   +V+    + F     + +K +Y L ADS   +EEWI +L  +L++
Sbjct: 617 IRKPQGQVDLNSRCQIVRGEGSQTFQL---ISEKKTYYLTADSPSLLEEWIRVLQSLLKV 673


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 20/142 (14%)

Query: 147 LPVHVYEVDEEVDKDED-------AASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRR 199
           +P   Y  D E  + E        ++S   +   + K G+L K      +S  ++S+KRR
Sbjct: 670 IPPDAYSTDTEYSQPEQKLPKTCSSSSDNGKNEPLEKSGYLLK------MSGKVKSWKRR 723

Query: 200 FFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYL 259
           +F L     G   L +     + ++P+G I L +   +++ +  +         +K +Y 
Sbjct: 724 WFVL----KGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLTT---EKHTYY 776

Query: 260 LAADSEVEMEEWITILNKILQL 281
           L ADS   +EEWI +L  +L++
Sbjct: 777 LTADSPNILEEWIKVLQNVLRV 798


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 60/225 (26%), Positives = 95/225 (42%), Gaps = 35/225 (15%)

Query: 155 DEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLN 214
           D +++ + DAA+      GI   G+L+K   N+      +++ RR+F  IQ     Y   
Sbjct: 254 DSKLEYNVDAAN------GIVMEGYLFKRASNA-----FKTWNRRWFS-IQNNQLVYQKK 301

Query: 215 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITI 274
           F  +  +  E      +  C  +      RRF FE+    KS  +L ADSE   + WI  
Sbjct: 302 FKDNPTVVVEDLRLCTVKHCEDIE-----RRFCFEVVSPTKSC-MLQADSEKLRQAWI-- 353

Query: 275 LNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESR 334
             K +Q +   A +EK  GD  E  ++     +GS LDS            E  LK ES 
Sbjct: 354 --KAVQTSIATAYREK--GDESEKLDKKSSPSTGS-LDS-------GNESKEKLLKGESA 401

Query: 335 VKLFYLDP-DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNL 378
           ++     P +A   D   A+P   S     G  + ++C+ +  +L
Sbjct: 402 LQRVQCIPGNASCCDCGLADPRWASI--NLGITLCIECSGIHRSL 444


>gi|24432056 hypothetical protein LOC144717 [Homo sapiens]
          Length = 249

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 13/101 (12%)

Query: 178 GWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSC-MG 236
           G+LYK     A      ++ RR+F L        N+ FY ++  S+EP G I L+ C + 
Sbjct: 22  GFLYKKGGRHA------AYHRRWFVL------RGNMLFYFEDAASREPVGVIILEGCTVE 69

Query: 237 VVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNK 277
           +V+  +   FA         +Y+LAA+S+  ME W+  L++
Sbjct: 70  LVEAAEEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSR 110


>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
          Length = 1242

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 17/123 (13%)

Query: 194 RSFKRRFFHLIQLGD--GSYNLNFYKDEKI----SKEPKGSIFLDSCMGVVQNNKVRRFA 247
           +S  +RFF L    +  G   L +Y++EK     S  PK SI L+SC  + +    +   
Sbjct: 23  KSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKH 82

Query: 248 FELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGS 307
                     + +AADSE E + W           ++A +Q       H D   +   G 
Sbjct: 83  LVALYTRDEHFAIAADSEAEQDSW-----------YQALLQLHNRAKGHHDGAAALGAGG 131

Query: 308 GSG 310
           G G
Sbjct: 132 GGG 134


>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
          Length = 1870

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 72/350 (20%), Positives = 139/350 (39%), Gaps = 53/350 (15%)

Query: 640 NHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAA 699
           N +YV   + ++D  K     +N+ + +   D  EE     K I+  PG      S + +
Sbjct: 444 NDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHD--EEGKLLEKAIH--PGAGYEGISEYKS 498

Query: 700 VLHHH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSW 758
           V+++  + P +Y+ +K+ +  +   + H+  TF H       + S + RD  E   G ++
Sbjct: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551

Query: 759 LPLLK-DGRVVTSEQHIPV--------------SANLPSGYLGYQ--ELGMGRHYGPEIK 801
           + L+  DG  +   +H  V                 LP   +  +  EL   ++      
Sbjct: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611

Query: 802 WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGH 861
             D  K   +I+T + ST  TQ+  L     +   +++        +   LK L  ++G 
Sbjct: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQN--------IKHNLKKLMEVDGG 663

Query: 862 VMIAFLPTILNQLFRVLTRATQEE--------VAVNVTRVIIHVVAQCHEEGLESHL--- 910
            ++ FL   L+ LF ++   +  E          V +  +I  +  Q     LE+++   
Sbjct: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723

Query: 911 ----RSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLL 956
                +YVK +     YVA+   +   EL  +    LK    F+  +++L
Sbjct: 724 FSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVL 773


>gi|238908495 similar to pleckstrin homology domain protein (5V327)
           [Homo sapiens]
          Length = 506

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)

Query: 196 FKRRFFHLIQLGDGSYNLNFYKDEKISKE--------PKGSIFLDSCMGVVQNNKVRRFA 247
           + RRFF + +    S+ L + + EK S E        PKG I L  C+   +      +A
Sbjct: 47  WSRRFFIIKE----SFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEPKEEPSMPYA 102

Query: 248 FELKMQD-KSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEG 306
            ++  QD   + LLAA+SE E  +W+ +L +  ++ ++ A   +    S E       + 
Sbjct: 103 MKISHQDFHGNILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKE 162

Query: 307 SGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP--DAQKLDFSSAEPEVKSFEEKFG 364
               LD  + E        E+ L+ E R +L  L+   +A+K  F     E++  +E+  
Sbjct: 163 KQEYLDKLMEE------TEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIK 216

Query: 365 KRI 367
           + +
Sbjct: 217 REL 219



 Score = 30.8 bits (68), Expect = 8.5
 Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 11/99 (11%)

Query: 274 ILNKILQLNFEAAMQEKRNGDSHE-----DDEQSKLEGSGSGLDSYLPELAKSAREAEIK 328
           I  K+ QL  E  + EKR  ++ E     ++E+         L + L EL    ++AE +
Sbjct: 291 IEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTAEKQQAERE 350

Query: 329 LKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRI 367
           LK+E +V++     D ++     AE  ++S E+    ++
Sbjct: 351 LKAEVKVRM-----DLER-RLREAEGALRSLEQGLNSKV 383


>gi|219689123 pleckstrin homology domain containing, family A member
           5 isoform 2 [Homo sapiens]
          Length = 1105

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%)

Query: 174 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 233
           + + GWLYK +     S  M+ +K+R+F L  L      L +Y+DEK  +   GSI L S
Sbjct: 62  VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 110

Query: 234 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 272
               +   +++  R++AF+    +  +Y    D+  EME W+
Sbjct: 111 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 152


>gi|19923493 pleckstrin homology domain containing, family A member
           5 isoform 1 [Homo sapiens]
          Length = 1116

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%)

Query: 174 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 233
           + + GWLYK +     S  M+ +K+R+F L  L      L +Y+DEK  +   GSI L S
Sbjct: 170 VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 218

Query: 234 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 272
               +   +++  R++AF+    +  +Y    D+  EME W+
Sbjct: 219 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 260


>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
          Length = 2030

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 57/224 (25%), Positives = 93/224 (41%), Gaps = 34/224 (15%)

Query: 676 DSQPLK-CIYGRPGGPVFTRSAFAA-VLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFH 733
           D + LK CI    G P   RS++ + VL+H  +P + + IK+ +P       HL   F H
Sbjct: 454 DGEILKDCISLGSGEP--NRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRH 511

Query: 734 VSCDNSSKGSTKKRDVVETQVGYSWLPLLK-DGRVVTSEQH--------IPVSANLPSGY 784
             C    KG  K         G+++  L++ DG  ++ + H           + N  + Y
Sbjct: 512 --CSTKDKGEKK-------LFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALY 562

Query: 785 LGYQELGMGRHYGPEIK----WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 840
           LG        +  P I     +    K    IST L ST  TQ+  L    ++       
Sbjct: 563 LGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKW------- 615

Query: 841 AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQE 884
            +A  + ++  L  L  + G  ++ FL  IL+ LF +L   T++
Sbjct: 616 -KAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDDNTEK 658


>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
           sapiens]
          Length = 358

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%)

Query: 215 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 269
           +Y +EK SK+PKG+ FL    GV     +RR +     FEL  QD+ SY   A S  E  
Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199

Query: 270 EWITILNKILQ------LNFEAAMQEKRNGDSHED 298
           +W+  ++ +L+      + +E   +E+   ++++D
Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234


>gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo
           sapiens]
          Length = 359

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%)

Query: 215 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 269
           +Y +EK SK+PKG+ FL    GV     +RR +     FEL  QD+ SY   A S  E  
Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199

Query: 270 EWITILNKILQ------LNFEAAMQEKRNGDSHED 298
           +W+  ++ +L+      + +E   +E+   ++++D
Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234


>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
          Length = 1830

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%)

Query: 698  AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 757
            + V +  + P + + +K+ +P +  ++ HL   F H       + S + +D  E     S
Sbjct: 478  SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530

Query: 758  WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 804
            ++ L+K DG  +    H  V     S  +     Y  L   RH+              V 
Sbjct: 531  YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590

Query: 805  G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 860
            G     + +  IST + ST  TQ+  L    ++  K +         L + L+ L  ++G
Sbjct: 591  GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642

Query: 861  HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 919
              ++ FL   L+ LF ++   +Q +E  + V   +I+++    +       R +  +   
Sbjct: 643  EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695

Query: 920  AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 971
             E Y+   +     +++L   + T L  S+        L + K L+Y  F F V  +++ 
Sbjct: 696  LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754

Query: 972  QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1003
              L E  +        F  S     E++ N++
Sbjct: 755  SQLYEGKE-----QMEFEESMRRLFESINNLM 781


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 46/170 (27%), Positives = 70/170 (41%), Gaps = 26/170 (15%)

Query: 143 KLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFH 202
           K D    HV    +E+  +E   SL    GG+   G L+K   N+      +++ RR+F 
Sbjct: 235 KRDMEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNA-----FKTWSRRWF- 288

Query: 203 LIQLGDGSYNLNFYKDEKISKEPKGSIF--LDSCMGVVQNNKVRRFAFELKMQDKSSYLL 260
            IQ     Y       +K  K+P   +   L  C   +  +  RRF FE+    KS  LL
Sbjct: 289 TIQSNQLVY-------QKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSC-LL 340

Query: 261 AADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSG 310
            ADSE  ++ W++ +   +   F  A            D+  +  G GSG
Sbjct: 341 QADSERLLQLWVSAVQSSIASAFSQARL----------DDSPRGPGQGSG 380


>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
           sapiens]
          Length = 676

 Score = 38.9 bits (89), Expect = 0.031
 Identities = 48/185 (25%), Positives = 89/185 (48%), Gaps = 29/185 (15%)

Query: 172 GGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYN---LNFYKDEKISKEPKGS 228
           G +   GWL K      +     ++K+R+F +++ G  S +   L +YK++  SK+P   
Sbjct: 5   GDVVCTGWLRKSPPEKKLR--RYAWKKRWF-ILRSGRMSGDPDVLEYYKNDH-SKKPLRI 60

Query: 229 IFLDSC----MGVVQNNKVRR--FAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282
           I L+ C     G+  N K  +  F F++K  +++ YL+ A++E +M +W+  + +I   N
Sbjct: 61  INLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV-AETEEDMNKWVQSICQICGFN 119

Query: 283 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKS-----ESRVKL 337
                Q + + DS  +     +  +G G  S   EL+ S++    + KS      S+  L
Sbjct: 120 -----QAEESTDSLRN-----VSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTL 169

Query: 338 FYLDP 342
           F  +P
Sbjct: 170 FTFEP 174


>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
          Length = 2390

 Score = 38.5 bits (88), Expect = 0.041
 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 14/127 (11%)

Query: 212  NLNFYKDEKISK-----EPKGSIFLDSCMGVVQ-NNKVRRFAFELKMQDKSSYLLAADSE 265
            +L FYKD K +        +  + L    G V  + + R+  F+L +QD   YL  A  E
Sbjct: 2254 SLGFYKDAKAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDE 2313

Query: 266  VEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREA 325
             EM  W+ ++N  +      A     +G+  E    S   G    +   +P ++    E 
Sbjct: 2314 AEMSSWLRVVNAAI------ATASSASGEPEEPVVPSTTRGMTRAMT--MPPVSPVGAEG 2365

Query: 326  EIKLKSE 332
             + L+S+
Sbjct: 2366 PVVLRSK 2372


>gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]
          Length = 359

 Score = 37.4 bits (85), Expect = 0.091
 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 22/138 (15%)

Query: 156 EEVDKDEDAASLGSQKGGIT--------KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLG 207
           E  DKD++A S G+Q   I         K G+L K   +   S     +++R+  L    
Sbjct: 91  ERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDH--SFLGFEWQKRWCAL---- 144

Query: 208 DGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRR-----FAFELKMQDKSSYLLAA 262
             S  + +Y      K+ KG   +D    V  NN +R+       FE+   DK  Y   A
Sbjct: 145 --SKTVFYYYGSDKDKQQKGEFAIDG-YSVRMNNTLRKDGKKDCCFEISAPDKRIYQFTA 201

Query: 263 DSEVEMEEWITILNKILQ 280
            S  + EEW+  L  +LQ
Sbjct: 202 ASPKDAEEWVQQLKFVLQ 219


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,739,654
Number of Sequences: 37866
Number of extensions: 2138402
Number of successful extensions: 5413
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 5288
Number of HSP's gapped (non-prelim): 128
length of query: 1253
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1139
effective length of database: 13,930,794
effective search space: 15867174366
effective search space used: 15867174366
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.