Guide to the Human Genome
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Search of human proteins with 194239707

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194239707 dedicator of cytokinesis 9 isoform c [Homo
sapiens]
         (1254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]     2523   0.0  
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]      2480   0.0  
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]     2444   0.0  
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]     2401   0.0  
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]              1429   0.0  
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]              1239   0.0  
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]                364   e-100
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]                273   8e-73
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]                 263   1e-69
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]                  46   3e-04
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]                   46   3e-04
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap...    46   3e-04
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi...    46   3e-04
gi|55741447 pleckstrin homology domain containing, family H (wit...    45   6e-04
gi|217416392 pleckstrin homology domain containing, family H (wi...    44   7e-04
gi|187608516 centaurin, beta 2 [Homo sapiens]                          42   0.003
gi|24432056 hypothetical protein LOC144717 [Homo sapiens]              42   0.004
gi|5031805 insulin receptor substrate 1 [Homo sapiens]                 41   0.008
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]                 41   0.008
gi|238908495 similar to pleckstrin homology domain protein (5V32...    40   0.011
gi|219689123 pleckstrin homology domain containing, family A mem...    40   0.011
gi|19923493 pleckstrin homology domain containing, family A memb...    40   0.011
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]                  40   0.018
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H...    40   0.018
gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H...    40   0.018
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]                  39   0.024
gi|7661880 centaurin beta1 [Homo sapiens]                              39   0.024
gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa...    39   0.031
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]           39   0.041
gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]      37   0.091

>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
          Length = 1254

 Score = 2523 bits (6540), Expect = 0.0
 Identities = 1254/1254 (100%), Positives = 1254/1254 (100%)

Query: 1    MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60
            MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ
Sbjct: 1    MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60

Query: 61   KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120
            KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD
Sbjct: 61   KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120

Query: 121  WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180
            WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW
Sbjct: 121  WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180

Query: 181  LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240
            LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ
Sbjct: 181  LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240

Query: 241  NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300
            NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD
Sbjct: 241  NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300

Query: 301  EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360
            EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF
Sbjct: 301  EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360

Query: 361  EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420
            EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL
Sbjct: 361  EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420

Query: 421  NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480
            NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE
Sbjct: 421  NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480

Query: 481  KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540
            KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL
Sbjct: 481  KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540

Query: 541  DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600
            DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV
Sbjct: 541  DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600

Query: 601  NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660
            NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK
Sbjct: 601  NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660

Query: 661  ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
            ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT
Sbjct: 661  ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720

Query: 721  QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780
            QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN
Sbjct: 721  QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780

Query: 781  LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840
            LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES
Sbjct: 781  LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840

Query: 841  GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900
            GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA
Sbjct: 841  GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900

Query: 901  QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960
            QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS
Sbjct: 901  QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960

Query: 961  WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020
            WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK
Sbjct: 961  WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020

Query: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080
            NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP
Sbjct: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080

Query: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140
            LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL
Sbjct: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140

Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200
            KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES
Sbjct: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200

Query: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ 1254
            LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ
Sbjct: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ 1254


>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
          Length = 2069

 Score = 2480 bits (6427), Expect = 0.0
 Identities = 1233/1235 (99%), Positives = 1234/1235 (99%)

Query: 1    MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60
            MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ
Sbjct: 1    MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60

Query: 61   KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120
            KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD
Sbjct: 61   KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120

Query: 121  WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180
            WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW
Sbjct: 121  WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180

Query: 181  LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240
            LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ
Sbjct: 181  LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240

Query: 241  NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300
            NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD
Sbjct: 241  NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300

Query: 301  EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360
            EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF
Sbjct: 301  EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360

Query: 361  EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420
            EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL
Sbjct: 361  EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420

Query: 421  NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480
            NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE
Sbjct: 421  NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480

Query: 481  KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540
            KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL
Sbjct: 481  KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540

Query: 541  DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600
            DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV
Sbjct: 541  DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600

Query: 601  NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660
            NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK
Sbjct: 601  NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660

Query: 661  ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
            ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT
Sbjct: 661  ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720

Query: 721  QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780
            QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN
Sbjct: 721  QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780

Query: 781  LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840
            LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES
Sbjct: 781  LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840

Query: 841  GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900
            GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA
Sbjct: 841  GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900

Query: 901  QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960
            QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS
Sbjct: 901  QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960

Query: 961  WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020
            WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK
Sbjct: 961  WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020

Query: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080
            NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP
Sbjct: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080

Query: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140
            LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL
Sbjct: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140

Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200
            KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES
Sbjct: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200

Query: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1235
            LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI +
Sbjct: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1235


>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
          Length = 1253

 Score = 2444 bits (6335), Expect = 0.0
 Identities = 1211/1211 (100%), Positives = 1211/1211 (100%)

Query: 44   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103
            AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE
Sbjct: 43   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102

Query: 104  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163
            EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE
Sbjct: 103  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162

Query: 164  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223
            DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS
Sbjct: 163  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222

Query: 224  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283
            KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN
Sbjct: 223  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282

Query: 284  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343
            FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP
Sbjct: 283  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342

Query: 344  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403
            DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL
Sbjct: 343  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402

Query: 404  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463
            FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI
Sbjct: 403  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462

Query: 464  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523
            FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM
Sbjct: 463  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522

Query: 524  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583
            PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG
Sbjct: 523  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582

Query: 584  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643
            NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL
Sbjct: 583  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642

Query: 644  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
            YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH
Sbjct: 643  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702

Query: 704  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763
            HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL
Sbjct: 703  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762

Query: 764  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823
            KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT
Sbjct: 763  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822

Query: 824  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883
            QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT
Sbjct: 823  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882

Query: 884  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943
            QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI
Sbjct: 883  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942

Query: 944  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003
            LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM
Sbjct: 943  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002

Query: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063
            LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE
Sbjct: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062

Query: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123
            YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG
Sbjct: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122

Query: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183
            TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR
Sbjct: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182

Query: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL 1243
            DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL
Sbjct: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL 1242

Query: 1244 STITLKVSWSQ 1254
            STITLKVSWSQ
Sbjct: 1243 STITLKVSWSQ 1253


>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
          Length = 2068

 Score = 2401 bits (6222), Expect = 0.0
 Identities = 1190/1192 (99%), Positives = 1191/1192 (99%)

Query: 44   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103
            AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE
Sbjct: 43   AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102

Query: 104  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163
            EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE
Sbjct: 103  EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162

Query: 164  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223
            DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS
Sbjct: 163  DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222

Query: 224  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283
            KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN
Sbjct: 223  KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282

Query: 284  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343
            FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP
Sbjct: 283  FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342

Query: 344  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403
            DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL
Sbjct: 343  DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402

Query: 404  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463
            FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI
Sbjct: 403  FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462

Query: 464  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523
            FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM
Sbjct: 463  FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522

Query: 524  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583
            PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG
Sbjct: 523  PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582

Query: 584  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643
            NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL
Sbjct: 583  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642

Query: 644  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
            YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH
Sbjct: 643  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702

Query: 704  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763
            HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL
Sbjct: 703  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762

Query: 764  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823
            KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT
Sbjct: 763  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822

Query: 824  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883
            QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT
Sbjct: 823  QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882

Query: 884  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943
            QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI
Sbjct: 883  QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942

Query: 944  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003
            LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM
Sbjct: 943  LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002

Query: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063
            LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE
Sbjct: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062

Query: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123
            YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG
Sbjct: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122

Query: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183
            TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR
Sbjct: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182

Query: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1235
            DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI +
Sbjct: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1234


>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
          Length = 2073

 Score = 1429 bits (3700), Expect = 0.0
 Identities = 705/1186 (59%), Positives = 908/1186 (76%), Gaps = 14/1186 (1%)

Query: 11   AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQKKTQILNDCL 70
            AE RKFT+ LSKPGTAAELRQSVSE VRGSV+L K K++EPLDYENVI Q+KTQI +D L
Sbjct: 2    AEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPL 61

Query: 71   REMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYED 130
            R++L+FP +D   +++ RQ R + STVP  AE+ AQSLFV ECIKTY++DWH+VNYKYED
Sbjct: 62   RDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYED 121

Query: 131  YSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAI 190
            +SG+FR LP K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I
Sbjct: 122  FSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTI 181

Query: 191  SVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFE 250
            +VTM+ FKRR+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ  K+RR AFE
Sbjct: 182  TVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFE 241

Query: 251  LKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLE 306
            LKM DK S+ LAA++E EMEEW+  L KI+Q+N ++ +QEK+   ++ +DDE   Q K E
Sbjct: 242  LKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAE 301

Query: 307  GSGSGLD-SYLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEE 362
               + L+ S  PEL K  RE E   K    + R  LF  D + Q+LDFS  EP++K FEE
Sbjct: 302  NIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEE 361

Query: 363  KFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNH 422
            K  KR LV C+DL+FN+   + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN 
Sbjct: 362  KCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNP 421

Query: 423  FSVRQMLATTSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARI 479
             SVR+ML  +S  L +      S  +  +H   E+ ++Y +QGIFSVT PHP+IFLVARI
Sbjct: 422  PSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARI 481

Query: 480  EKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGN 539
            EKVLQG+ITHCAEPY+K+SD  K AQKV + AKQ C RLGQYRMPFAWAAR +FKD  G+
Sbjct: 482  EKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGS 541

Query: 540  LDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNY 599
            LD + RFS +Y+QDS+KLS++D+LKLL++++KPEK  KL +I G L+IT++ V  D  N 
Sbjct: 542  LDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNC 600

Query: 600  VNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFA 659
            + SSY+P K FE   +  IT EVEEFVP + K+  P+TIY NHLYVYP  LKYDSQK+FA
Sbjct: 601  ITSSYVPLKPFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFA 659

Query: 660  KARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELP 719
            KARNIA+C+EF+DSDE D+  LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP
Sbjct: 660  KARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELP 719

Query: 720  TQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSA 779
              LH+KHHLL TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSA
Sbjct: 720  IHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSA 779

Query: 780  NLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTE 839
            NLP GYL   +    R    +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ  +
Sbjct: 780  NLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQ 839

Query: 840  SGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHV 898
            SG++ +  EL+KYLK LHAME  VMI FLP IL QLFRVLT  T E+ V +N T V++H+
Sbjct: 840  SGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHI 899

Query: 899  VAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLK 958
            V++CHEEGL+S+LRS++KY+++ E   A + + +HE L  +M  ILK SADFL+ NKLLK
Sbjct: 900  VSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLK 959

Query: 959  YSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEA 1018
            YSWFFF+++ KSMA +L+E +K+KL R QRFP +YHH + +++  ++PH+T ++ + P+ 
Sbjct: 960  YSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDE 1019

Query: 1019 SKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHY 1078
            S+N N+SLA F+KRC T MDRGF+F  IN+YIS F+P DPK L EYKFEFL+ +CNHEHY
Sbjct: 1020 SRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHY 1079

Query: 1079 IPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1138
            IPLNLPM F K ++QR QD  L+YSL+DE+C++HFLVGLLLRE   ALQ+  E+R  AIS
Sbjct: 1080 IPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAIS 1139

Query: 1139 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRD 1184
            V+KNLLIKH+FD RY  ++ QA+IA LYLP  GLL+EN+QR+  RD
Sbjct: 1140 VIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRD 1185


>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
          Length = 2186

 Score = 1239 bits (3207), Expect = 0.0
 Identities = 638/1284 (49%), Positives = 893/1284 (69%), Gaps = 59/1284 (4%)

Query: 9    ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLA------KPKLIEPLDYENVIVQKK 62
            A   TR+FTR+L +PG AAELR S +     +V         KP+L+EPLDYE VI + +
Sbjct: 2    AGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELE 61

Query: 63   TQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWH 122
                ND L+++L FP DDF  A +    R + STVP  AE +A++L V E  K Y+S WH
Sbjct: 62   KTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWH 121

Query: 123  LVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDEDAASLGSQKGG------- 174
            +VNYKYE YSG+ RQLP    K +KLP H +E+D E+ DKDED  S  S KGG       
Sbjct: 122  VVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTG 181

Query: 175  ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFL 232
            + K GWLYKGN NS ++  VT+RSFK+R+F L QL D SY +NFYKDEKISKEPKG IFL
Sbjct: 182  VFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFL 241

Query: 233  DSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKR 292
            DSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI  LN+ILQ++ E  +Q +R
Sbjct: 242  DSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRR 301

Query: 293  NG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSAREAEIKLKSE---SRVKLFY 340
            +        DS ++    +   E + S  ++   + AK   E E  +K+     R+ LF 
Sbjct: 302  STELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFS 361

Query: 341  LDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVE 395
            LDPD      QK D    E  +K FEEK  KRI++ C  L+ NLQ CV ENE  P TN+E
Sbjct: 362  LDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIE 421

Query: 396  PFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGS--------GQSPSVL 447
            PFFV+++L+D++ +RKISADFHVDLNH +VRQML   S AL NG+         + P + 
Sbjct: 422  PFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI- 480

Query: 448  KGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKV 507
            KG L E  +++PKQ +FSV+ PH +I LVA+IEKVL G+I   AEPY+K+ DS+K AQK+
Sbjct: 481  KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKI 539

Query: 508  LKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLA 567
            LK+ +Q C +LG+YRMPFAWA R++FKD  GN+D+++RFS ++RQ+S+K+S +D++KL++
Sbjct: 540  LKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVS 599

Query: 568  DFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVP 627
            D+R+ ++++K+  I G+LDI +DNV  + PN V SS+IP K F   ++T  T EVEEFV 
Sbjct: 600  DYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVY 659

Query: 628  CIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGR 687
               K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIEFK+SDEE ++PLKCIYG+
Sbjct: 660  DSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGK 719

Query: 688  PGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKK 747
            PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L +F+HV+CD ++K + KK
Sbjct: 720  PGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKK 779

Query: 748  RDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGG 807
            ++ +ET VGY+WLPL+K  ++ + E +IP++ +LP  YL +Q+   G+H G +IKWVDGG
Sbjct: 780  KEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGG 839

Query: 808  KPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNELVKYLKSLHAMEG-HVMI 865
            KPL K+ST +VSTV TQD H++ FFQ CQK E   +Q+  +  ++  K+L  +E  H ++
Sbjct: 840  KPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIM 899

Query: 866  AFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYV 925
            +FLP ILNQLF+VL +  ++E+   VTRV+  +VA+CHEE L+  ++SY+K+ +K     
Sbjct: 900  SFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTR--- 956

Query: 926  ASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLR 985
            A + +TVHEEL K++T +LK S D  T   +LK+SWFFF +++KSMAQHLI+ +K++L R
Sbjct: 957  ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPR 1015

Query: 986  NQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQ 1045
             QRFP SY + ++ +V +L  H+  K++D  E ++ ANHS+A F+KRCFTFMDRG+VFK 
Sbjct: 1016 PQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKM 1075

Query: 1046 INNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-----MPFGKGRIQRYQDLQL 1100
            +NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP     +P      +  Q+L  
Sbjct: 1076 VNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHA 1135

Query: 1101 ----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKHSFDDRYASR 1156
                +YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++VLKNL+ KHSFDDRY   
Sbjct: 1136 SDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREP 1195

Query: 1157 SHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVKDESLALPAVNPLVTPQKG 1215
              QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN +    +D+             +  
Sbjct: 1196 RKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHA 1255

Query: 1216 STLDNSLHKDLLGAISGIGNAPCS 1239
            +++D S  KD+L +I+   +   S
Sbjct: 1256 NSVDTSFSKDVLNSIAAFSSIAIS 1279


>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
          Length = 2047

 Score =  364 bits (934), Expect = e-100
 Identities = 304/1061 (28%), Positives = 473/1061 (44%), Gaps = 211/1061 (19%)

Query: 285  EAAMQEKRNGDSHEDDEQSKLEGSGSGL-----DSYLPELAKSAREAEIKLKSES----- 334
            E +   +R   S ED  +S    S   L     DS LP L + A   ++  ++E+     
Sbjct: 167  EDSNDSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQH 226

Query: 335  ---RVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPT 391
                +   Y  PD  +     + PE     E FG+RILVKC  L F ++           
Sbjct: 227  RPPALLTLYPAPDEDEAVERCSRPEPP--REHFGQRILVKCLSLKFEIE----------- 273

Query: 392  TNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGIL 451
              +EP F  L+L+D++  +KIS +F+ DLN  S++ +L                      
Sbjct: 274  --IEPIFGILALYDVREKKKISENFYFDLNSDSMKGLLRAHGT----------------- 314

Query: 452  HEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPYM--KSSDSSKVAQKVL 508
            H A     +  IFSVT P PDIFLV ++EKVLQ G I+ C EPYM  K  D++K  +K+ 
Sbjct: 315  HPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLE 374

Query: 509  K---NAKQACQRLGQYRMPFAWAARTLFK--DASGNLDKNA------------------- 544
            K    A+Q C RLG+YRMPFAW A  L     ++G LD+++                   
Sbjct: 375  KLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQ 434

Query: 545  ----------RFSAI----------YRQDSNKLSNDDMLKLLADFRKPEKMAK-LPVILG 583
                       FS            ++Q++ +LS++D+ K LAD R+P  + + L  +  
Sbjct: 435  DRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTA 494

Query: 584  NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643
             L I I     +    ++   +  K +      P T E+ EF P    +  P+T Y N L
Sbjct: 495  QLKIDISPAPENPHFCLSPELLHIKPYPDPRGRP-TKEILEF-PAREVYA-PHTSYRNLL 551

Query: 644  YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
            YVYP  L + S++     RN+A+ +++  + E+ SQ L  I+G+     FTR AF  V++
Sbjct: 552  YVYPHSLNFSSRQG--SVRNLAVRVQYM-TGEDPSQALPVIFGKSSCSEFTREAFTPVVY 608

Query: 704  HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763
            H+++PEFY+E K+ LP  + E HHLL TF+HVSC        +    +ET VG++W+PLL
Sbjct: 609  HNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSC------QPRPGTALETPVGFTWIPLL 662

Query: 764  KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823
            + GR+ T    +PVS + P          +     P ++WVDG K +  +    VS+V+ 
Sbjct: 663  QHGRLRTGPFCLPVSVDQPPPSYSVLTPDVAL---PGMRWVDGHKGVFSVELTAVSSVHP 719

Query: 824  QDQHLHNFFQYCQKTESGA---------QALGN---ELVKYLKSLHAMEGHVMIAFLPTI 871
            QD +L  FF      E GA          + GN   EL   L +L       ++AF   +
Sbjct: 720  QDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHV 779

Query: 872  LNQLFRVLTR-ATQEEVAVNVTR----VIIHVVAQCHE--------EGLESHLRSYVKYA 918
            L++L R++ R        VN+ R     + HVV+  H          G    L +YV YA
Sbjct: 780  LDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYA 839

Query: 919  YK----------AEPYVASEYKTVHEELTKSMTTILKPSADFLTSN-------------- 954
            ++            P V  +  T+     +  +  L  S    +SN              
Sbjct: 840  FRLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEV 899

Query: 955  --------------------------KLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQR 988
                                       +L+++WFFF +++KSMA HL+   ++   R  R
Sbjct: 900  SRILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLR 959

Query: 989  FPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINN 1048
            FP  +   +  +V  +   +  +   + E +++ N SLA F+    + +DRGFVF  +  
Sbjct: 960  FPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRA 1019

Query: 1049 YISCFA-----PGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-------------MPFGKG 1090
            +    A       +P  L   + EF R++C+HEHY+ LNLP             +     
Sbjct: 1020 HYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTS 1079

Query: 1091 RIQRYQDLQLD------YSLTDEFCRNHFLVGLLLREVGTALQEFREVRLI----AISVL 1140
            +   +     D      + L+  F + HFL GLLL E+  AL+   E   +    AIS +
Sbjct: 1080 QSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAV 1139

Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRIN 1181
             +LL  H  D RYA  + +AR+A LYLPL  +  + + R++
Sbjct: 1140 HSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLH 1180



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 16/165 (9%)

Query: 9   ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAK----------PKLIEPLDYENVI 58
           A++E R F   +++   AAE+R+ VS    GS   ++           +++EPLD+E+V+
Sbjct: 2   AASERRAFAHKINRT-VAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVL 60

Query: 59  VQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYN 118
           + +        LR+++ FP DD +  +  R+ R   +T P   ++E     V   ++ Y 
Sbjct: 61  LSRPPDAEPGPLRDLVEFPADDLELLLQPRECR---TTEPGIPKDEKLDAQVRAAVEMYI 117

Query: 119 SDWHLVNYKYEDYSGEFRQLPNKVVKLDK--LPVHVYEVDEEVDK 161
            DW +V+ +Y+  S  +  +     +  +  LP  V+E D   D+
Sbjct: 118 EDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDE 162


>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
          Length = 2099

 Score =  273 bits (698), Expect = 8e-73
 Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%)

Query: 324 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 383
           ++ E   ++  + +LF L P   + D     P  +  +E  G RILVK   L F ++   
Sbjct: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280

Query: 384 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 443
                     +EP F +++L+D+K  +KIS +FH DLN    +  L   +P++       
Sbjct: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323

Query: 444 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 500
                     AA    +  +FSVT P  DI+LV +IEKVLQ G I  CAEPY  +K SD 
Sbjct: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373

Query: 501 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 529
            K  +K+ K   QA   CQRLG+YRMPFAWA                             
Sbjct: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433

Query: 530 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 571
              RTL       + + +L++N             S+ ++Q+ ++LS++D+ K LAD+++
Sbjct: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493

Query: 572 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 630
              + + +  I G L + I          +    +P K F   ++T    E+ EF P   
Sbjct: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551

Query: 631 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 690
            +  P+T+Y N LYVYP+ L + ++   A ARNI I I+F    E+ S  +  I+G+  G
Sbjct: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607

Query: 691 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 750
           P F +  + AV +H+++P+FY+E+KI+LP +L   HHLL TF+H+SC      S      
Sbjct: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661

Query: 751 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 809
           VET +GYSWLP+L + R+ T    +PV+   LP  Y  +    +     P IKW +G K 
Sbjct: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720

Query: 810 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 856
           +  I    VS+V+TQD HL  FF  C   ES                AL +EL   +  L
Sbjct: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780

Query: 857 HAMEGHVMIAFLPTILNQLFRV 878
           ++     ++ FL  +L++LF++
Sbjct: 781 NSSRLEPLVLFLHLVLDKLFQL 802



 Score =  138 bits (348), Expect = 3e-32
 Identities = 94/286 (32%), Positives = 143/286 (50%), Gaps = 32/286 (11%)

Query: 921  AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 980
            A P  AS+ K  HEEL   M       +  +    + KY+WFFF++L+KSMAQH+    K
Sbjct: 950  AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003

Query: 981  VKLLRNQRFPASYHHAVETVVNMLMPHITQ---KFRDNPEASKNANHSLAVFIKRCFTFM 1037
                R  RF   +   + T+VN++   I     K +   E ++  N SLA F+    + M
Sbjct: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLM 1063

Query: 1038 DRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL-----------P 1084
            DRGFVF  I +Y S  +    +  TL   + EFLR++C+HEHY+ LNL           P
Sbjct: 1064 DRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSP 1123

Query: 1085 MPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVRL 1134
             P            +QD ++   + LT E+ + HFL GLL  E+  AL    +   +V+ 
Sbjct: 1124 CPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQR 1183

Query: 1135 IAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRI 1180
             A+S + +LL  H  D R      + +IA LYLPL G++++ + ++
Sbjct: 1184 KAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQL 1229



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 18/169 (10%)

Query: 9   ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKL---IEPLDYENVIVQKKTQI 65
           +SAE RK  +    P      RQS+S    G   L  P+    +EP+D+E +++     +
Sbjct: 20  SSAEIRK--QFTLPPNLGQYHRQSIS--TSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSL 75

Query: 66  LNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL--FVTECIKTYNSDWHL 123
                +E+  F  DD       ++    C T+     EE   L   V +C++TY  +W +
Sbjct: 76  DVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVELDPHVRDCVQTYIREWLI 131

Query: 124 VNYKYE---DYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLG 169
           VN K +   +  G F++  ++      LP   +E  E ++  E AA  G
Sbjct: 132 VNRKNQGSPEICG-FKKTGSRKDFHKTLPKQTFE-SETLECSEPAAQAG 178


>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
          Length = 2109

 Score =  263 bits (671), Expect = 1e-69
 Identities = 206/698 (29%), Positives = 338/698 (48%), Gaps = 137/698 (19%)

Query: 313 DSYLPELAKSAREAEI------KLKSESRVKLFYL--DPDAQKLDFSSAEPEVKSFEEKF 364
           D+ LP L       EI      + KS    +LF L   PD ++     + P++   +E F
Sbjct: 204 DALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDIP--KEHF 261

Query: 365 GKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFS 424
           G+R+LVKC  L F ++             +EP F +L+L+D+K  +KIS +F+ DLN   
Sbjct: 262 GQRLLVKCLSLKFEIE-------------IEPIFASLALYDVKEKKKISENFYFDLNSEQ 308

Query: 425 VRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ 484
           ++ +L    P         P+ +  +   A        IFS+T P  D+FLV ++EKVLQ
Sbjct: 309 MKGLLRPHVP---------PAAITTLARSA--------IFSITYPSQDVFLVIKLEKVLQ 351

Query: 485 -GSITHCAEPYM--KSSDSSKVAQKVLK---NAKQACQRLGQYRMPFAWAARTLFK--DA 536
            G I  CAEPYM  K +D++K  +K+ K    A Q CQRLG+YRMPFAW A  L     +
Sbjct: 352 QGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSS 411

Query: 537 SGNLDKNA-----------------RFSAI------------------------------ 549
           +G+L++++                 R S+I                              
Sbjct: 412 AGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTN 471

Query: 550 -YRQDSNKLSNDDMLKLLADFRKPEK-MAKLPVILGNLDITIDNVSSDFPNYVNSSYIPT 607
            ++Q+ ++LS++D+ K LAD R+P   + +L  I   L I I     + P+Y  +  +  
Sbjct: 472 FFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPEN-PHYCLTPELLQ 530

Query: 608 KQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAIC 667
            +    S+   T E+ EF P    +  P T Y N LY+YP+ L + +++    ARNI + 
Sbjct: 531 VKLYPDSRVRPTREILEF-PARDVYV-PNTTYRNLLYIYPQSLNFANRQG--SARNITVK 586

Query: 668 IEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHH 727
           ++F    E+ S  +  I+G+     F++ A+ AV++H+++P+F++EIK++LP  L + HH
Sbjct: 587 VQFMYG-EDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHH 645

Query: 728 LLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLG 787
           LL TF+HVSC        K+   +ET VGY+W+P+L++GR+ T +  +PVS   P     
Sbjct: 646 LLFTFYHVSCQQ------KQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPP--QA 697

Query: 788 YQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG------ 841
           Y  L       P +KWVD  K +  +    VS+++TQD +L  FF      +        
Sbjct: 698 YSVLSPEVPL-PGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHLFPVRI 756

Query: 842 ------AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTR-------------A 882
                    L NEL   + +L++ +   ++ FL  +L++L  ++ R             A
Sbjct: 757 GDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQA 816

Query: 883 TQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920
           + E +A  + R+  ++     + G  S L SY+ Y ++
Sbjct: 817 SFEAMASIINRLHKNLEGNHDQHGRNSLLASYIHYVFR 854



 Score =  136 bits (343), Expect = 1e-31
 Identities = 80/254 (31%), Positives = 132/254 (51%), Gaps = 32/254 (12%)

Query: 957  LKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNP 1016
            L+ +WFFF++++KSM  HL  N K++  R  RFP  +   +  +V+ +   I  +F+ + 
Sbjct: 974  LQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPERFMDDIAALVSTIASDIVSRFQKDT 1033

Query: 1017 EASKNANHSLAVFIKRCFTFMDRGFVF-------KQINNYISCFAPGDPKTLFEYKFEFL 1069
            E  +  N SLA F+    + MDRGFVF       KQ+++ +  ++  +P  L   + +FL
Sbjct: 1034 EMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSSKL--YSLPNPSVLVSLRLDFL 1091

Query: 1070 RVVCNHEHYIPLNLPMPF-----------------GKGRIQRYQDLQLD--YSLTDEFCR 1110
            R++C+HEHY+ LNLP                      G     QD ++   + L+  F +
Sbjct: 1092 RIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQ 1151

Query: 1111 NHFLVGLLLREVGTALQEFRE----VRLIAISVLKNLLIKHSFDDRYASRSHQARIATLY 1166
             H+L GL+L E+   L    E    +    I+++ NLL  H  D RY+    +AR+A LY
Sbjct: 1152 QHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLY 1211

Query: 1167 LPLFGLLIENVQRI 1180
            LPL G+++E V ++
Sbjct: 1212 LPLIGIIMETVPQL 1225



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 50/170 (29%), Positives = 77/170 (45%), Gaps = 26/170 (15%)

Query: 11  AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAK----------------PKLIEPLDY 54
           AE R F + +S+   AAE+R+ +S    GS  L K                 + ++P+D 
Sbjct: 2   AERRAFAQKISRT-VAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDL 60

Query: 55  ENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECI 114
           E+ ++     + +  LR+++ FP DD +     R  R + S VP   EE      V +CI
Sbjct: 61  EDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVP---EESEMDPHVRDCI 117

Query: 115 KTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDK----LPVHVYEVDEEVD 160
           ++Y  DW +V  KY      F   PN + K  +    LP  V+E DE  D
Sbjct: 118 RSYTEDWAIVIRKYHKLGTGFN--PNTLDKQKERQKGLPKQVFESDEAPD 165


>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
          Length = 1966

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 55/248 (22%), Positives = 102/248 (41%), Gaps = 31/248 (12%)

Query: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720
           ARN+ + +   DS     Q LK       G        + VL+H+ +P + + +K+ +P 
Sbjct: 421 ARNVEVTMFIVDSS---GQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477

Query: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL-KDGRVVTSEQHIPV-- 777
                 H+   F H  C    KG  K         G+S++PL+ +DGR +    H  +  
Sbjct: 478 DKFRGAHIRFEFRH--CSTKEKGEKK-------LFGFSFVPLMQEDGRTLPDGTHELIVH 528

Query: 778 ----SANL--PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNF 831
               + NL   + YL       G   G   + +   K    I++ L ST  TQ+  + + 
Sbjct: 529 KCEENTNLQDTTRYLKL-PFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDL 587

Query: 832 FQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNV 891
            ++        +   +++   L  L  ++G  ++ FL   L+ LF +L   +Q +    V
Sbjct: 588 LKW--------RTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDENSQ-KYGSKV 638

Query: 892 TRVIIHVV 899
              ++H++
Sbjct: 639 FDSLVHII 646


>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
          Length = 1865

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 75/342 (21%), Positives = 146/342 (42%), Gaps = 43/342 (12%)

Query: 645 VYPKYLKYDSQK-SFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703
           +Y   ++ D  K S   A+N+ + +   D   ED + L+ +   PG      S + +V++
Sbjct: 428 IYVTLVQGDFDKGSKTTAKNVEVTVSVYD---EDGKRLEHVIF-PGAGDEAISEYKSVIY 483

Query: 704 HH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPL 762
           +  + P +++ +K+ +P +   + HL  TF H S  +S   S K   +   ++       
Sbjct: 484 YQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTT 543

Query: 763 LKDGR----VVTSE----QHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDG---GKPLL 811
           L+DG     V  +E    +      +LPS     +E G     G  ++ +      K   
Sbjct: 544 LRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSA-TGKSMQSLGSCTISKDSF 602

Query: 812 KISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTI 871
           +IST + ST  TQ+  L    ++   T        + L + L+ L  ++G  ++ FL   
Sbjct: 603 QISTLVCSTKLTQNVDLLGLLKWRSNT--------SLLQQNLRQLMKVDGGEVVKFLQDT 654

Query: 872 LNQLFRVLTRATQEE----VAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKA------ 921
           L+ LF ++   ++ E    +  +    II ++A    +     L +Y+K  + A      
Sbjct: 655 LDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTK 714

Query: 922 -----EPYV-ASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957
                + YV  +E   V+E+L K+M   L+    F+  +++L
Sbjct: 715 LTKVLKNYVDGAEKPGVNEQLYKAMKA-LESIFKFIVRSRIL 755


>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
           sapiens]
          Length = 645

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%)

Query: 177 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 236
           K GWL K          ++++++R+F L      +  L +YKDE+ +K P+G ++L  C 
Sbjct: 49  KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 96

Query: 237 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 279
              +  N  +  +F FE+           + SY+L A S+ EMEEW+  L ++
Sbjct: 97  IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 149


>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
           sapiens]
          Length = 638

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%)

Query: 177 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 236
           K GWL K          ++++++R+F L      +  L +YKDE+ +K P+G ++L  C 
Sbjct: 42  KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 89

Query: 237 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 279
              +  N  +  +F FE+           + SY+L A S+ EMEEW+  L ++
Sbjct: 90  IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 142


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 17/120 (14%)

Query: 164 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEK-I 222
           D   LG +   + K G+L K  M S +    +++KRR+F L Q       + +YK    +
Sbjct: 570 DGLGLGGES--LEKSGYLLK--MGSQV----KTWKRRWFVLRQ-----GQIMYYKSPSDV 616

Query: 223 SKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQL 282
            ++P+G + L+S   +V+    + F     + +K +Y L ADS   +EEWI +L  +L++
Sbjct: 617 IRKPQGQVDLNSRCQIVRGEGSQTFQL---ISEKKTYYLTADSPSLLEEWIRVLQSLLKV 673


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 20/142 (14%)

Query: 148 LPVHVYEVDEEVDKDED-------AASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRR 200
           +P   Y  D E  + E        ++S   +   + K G+L K      +S  ++S+KRR
Sbjct: 670 IPPDAYSTDTEYSQPEQKLPKTCSSSSDNGKNEPLEKSGYLLK------MSGKVKSWKRR 723

Query: 201 FFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYL 260
           +F L     G   L +     + ++P+G I L +   +++ +  +         +K +Y 
Sbjct: 724 WFVL----KGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLTT---EKHTYY 776

Query: 261 LAADSEVEMEEWITILNKILQL 282
           L ADS   +EEWI +L  +L++
Sbjct: 777 LTADSPNILEEWIKVLQNVLRV 798


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 60/225 (26%), Positives = 95/225 (42%), Gaps = 35/225 (15%)

Query: 156 DEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLN 215
           D +++ + DAA+      GI   G+L+K   N+      +++ RR+F  IQ     Y   
Sbjct: 254 DSKLEYNVDAAN------GIVMEGYLFKRASNA-----FKTWNRRWFS-IQNNQLVYQKK 301

Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITI 275
           F  +  +  E      +  C  +      RRF FE+    KS  +L ADSE   + WI  
Sbjct: 302 FKDNPTVVVEDLRLCTVKHCEDIE-----RRFCFEVVSPTKSC-MLQADSEKLRQAWI-- 353

Query: 276 LNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESR 335
             K +Q +   A +EK  GD  E  ++     +GS LDS            E  LK ES 
Sbjct: 354 --KAVQTSIATAYREK--GDESEKLDKKSSPSTGS-LDS-------GNESKEKLLKGESA 401

Query: 336 VKLFYLDP-DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNL 379
           ++     P +A   D   A+P   S     G  + ++C+ +  +L
Sbjct: 402 LQRVQCIPGNASCCDCGLADPRWASI--NLGITLCIECSGIHRSL 444


>gi|24432056 hypothetical protein LOC144717 [Homo sapiens]
          Length = 249

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 13/101 (12%)

Query: 179 GWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSC-MG 237
           G+LYK     A      ++ RR+F L        N+ FY ++  S+EP G I L+ C + 
Sbjct: 22  GFLYKKGGRHA------AYHRRWFVL------RGNMLFYFEDAASREPVGVIILEGCTVE 69

Query: 238 VVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNK 278
           +V+  +   FA         +Y+LAA+S+  ME W+  L++
Sbjct: 70  LVEAAEEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSR 110


>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
          Length = 1242

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 17/123 (13%)

Query: 195 RSFKRRFFHLIQLGD--GSYNLNFYKDEKI----SKEPKGSIFLDSCMGVVQNNKVRRFA 248
           +S  +RFF L    +  G   L +Y++EK     S  PK SI L+SC  + +    +   
Sbjct: 23  KSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKH 82

Query: 249 FELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGS 308
                     + +AADSE E + W           ++A +Q       H D   +   G 
Sbjct: 83  LVALYTRDEHFAIAADSEAEQDSW-----------YQALLQLHNRAKGHHDGAAALGAGG 131

Query: 309 GSG 311
           G G
Sbjct: 132 GGG 134


>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
          Length = 1870

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 72/350 (20%), Positives = 139/350 (39%), Gaps = 53/350 (15%)

Query: 641 NHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAA 700
           N +YV   + ++D  K     +N+ + +   D  EE     K I+  PG      S + +
Sbjct: 444 NDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHD--EEGKLLEKAIH--PGAGYEGISEYKS 498

Query: 701 VLHHH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSW 759
           V+++  + P +Y+ +K+ +  +   + H+  TF H       + S + RD  E   G ++
Sbjct: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551

Query: 760 LPLLK-DGRVVTSEQHIPV--------------SANLPSGYLGYQ--ELGMGRHYGPEIK 802
           + L+  DG  +   +H  V                 LP   +  +  EL   ++      
Sbjct: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611

Query: 803 WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGH 862
             D  K   +I+T + ST  TQ+  L     +   +++        +   LK L  ++G 
Sbjct: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQN--------IKHNLKKLMEVDGG 663

Query: 863 VMIAFLPTILNQLFRVLTRATQEE--------VAVNVTRVIIHVVAQCHEEGLESHL--- 911
            ++ FL   L+ LF ++   +  E          V +  +I  +  Q     LE+++   
Sbjct: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723

Query: 912 ----RSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957
                +YVK +     YVA+   +   EL  +    LK    F+  +++L
Sbjct: 724 FSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVL 773


>gi|238908495 similar to pleckstrin homology domain protein (5V327)
           [Homo sapiens]
          Length = 506

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)

Query: 197 FKRRFFHLIQLGDGSYNLNFYKDEKISKE--------PKGSIFLDSCMGVVQNNKVRRFA 248
           + RRFF + +    S+ L + + EK S E        PKG I L  C+   +      +A
Sbjct: 47  WSRRFFIIKE----SFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEPKEEPSMPYA 102

Query: 249 FELKMQD-KSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEG 307
            ++  QD   + LLAA+SE E  +W+ +L +  ++ ++ A   +    S E       + 
Sbjct: 103 MKISHQDFHGNILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKE 162

Query: 308 SGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP--DAQKLDFSSAEPEVKSFEEKFG 365
               LD  + E        E+ L+ E R +L  L+   +A+K  F     E++  +E+  
Sbjct: 163 KQEYLDKLMEE------TEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIK 216

Query: 366 KRI 368
           + +
Sbjct: 217 REL 219



 Score = 30.8 bits (68), Expect = 8.5
 Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 11/99 (11%)

Query: 275 ILNKILQLNFEAAMQEKRNGDSHE-----DDEQSKLEGSGSGLDSYLPELAKSAREAEIK 329
           I  K+ QL  E  + EKR  ++ E     ++E+         L + L EL    ++AE +
Sbjct: 291 IEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTAEKQQAERE 350

Query: 330 LKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRI 368
           LK+E +V++     D ++     AE  ++S E+    ++
Sbjct: 351 LKAEVKVRM-----DLER-RLREAEGALRSLEQGLNSKV 383


>gi|219689123 pleckstrin homology domain containing, family A member
           5 isoform 2 [Homo sapiens]
          Length = 1105

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%)

Query: 175 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 234
           + + GWLYK +     S  M+ +K+R+F L  L      L +Y+DEK  +   GSI L S
Sbjct: 62  VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 110

Query: 235 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 273
               +   +++  R++AF+    +  +Y    D+  EME W+
Sbjct: 111 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 152


>gi|19923493 pleckstrin homology domain containing, family A member
           5 isoform 1 [Homo sapiens]
          Length = 1116

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%)

Query: 175 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 234
           + + GWLYK +     S  M+ +K+R+F L  L      L +Y+DEK  +   GSI L S
Sbjct: 170 VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 218

Query: 235 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 273
               +   +++  R++AF+    +  +Y    D+  EME W+
Sbjct: 219 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 260


>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
          Length = 2030

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 57/224 (25%), Positives = 93/224 (41%), Gaps = 34/224 (15%)

Query: 677 DSQPLK-CIYGRPGGPVFTRSAFAA-VLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFH 734
           D + LK CI    G P   RS++ + VL+H  +P + + IK+ +P       HL   F H
Sbjct: 454 DGEILKDCISLGSGEP--NRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRH 511

Query: 735 VSCDNSSKGSTKKRDVVETQVGYSWLPLLK-DGRVVTSEQH--------IPVSANLPSGY 785
             C    KG  K         G+++  L++ DG  ++ + H           + N  + Y
Sbjct: 512 --CSTKDKGEKK-------LFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALY 562

Query: 786 LGYQELGMGRHYGPEIK----WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 841
           LG        +  P I     +    K    IST L ST  TQ+  L    ++       
Sbjct: 563 LGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKW------- 615

Query: 842 AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQE 885
            +A  + ++  L  L  + G  ++ FL  IL+ LF +L   T++
Sbjct: 616 -KAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDDNTEK 658


>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
           sapiens]
          Length = 358

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%)

Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 270
           +Y +EK SK+PKG+ FL    GV     +RR +     FEL  QD+ SY   A S  E  
Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199

Query: 271 EWITILNKILQ------LNFEAAMQEKRNGDSHED 299
           +W+  ++ +L+      + +E   +E+   ++++D
Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234


>gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo
           sapiens]
          Length = 359

 Score = 39.7 bits (91), Expect = 0.018
 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%)

Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 270
           +Y +EK SK+PKG+ FL    GV     +RR +     FEL  QD+ SY   A S  E  
Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199

Query: 271 EWITILNKILQ------LNFEAAMQEKRNGDSHED 299
           +W+  ++ +L+      + +E   +E+   ++++D
Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234


>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
          Length = 1830

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%)

Query: 699  AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 758
            + V +  + P + + +K+ +P +  ++ HL   F H       + S + +D  E     S
Sbjct: 478  SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530

Query: 759  WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 805
            ++ L+K DG  +    H  V     S  +     Y  L   RH+              V 
Sbjct: 531  YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590

Query: 806  G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 861
            G     + +  IST + ST  TQ+  L    ++  K +         L + L+ L  ++G
Sbjct: 591  GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642

Query: 862  HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920
              ++ FL   L+ LF ++   +Q +E  + V   +I+++    +       R +  +   
Sbjct: 643  EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695

Query: 921  AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 972
             E Y+   +     +++L   + T L  S+        L + K L+Y  F F V  +++ 
Sbjct: 696  LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754

Query: 973  QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1004
              L E  +        F  S     E++ N++
Sbjct: 755  SQLYEGKE-----QMEFEESMRRLFESINNLM 781


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 39.3 bits (90), Expect = 0.024
 Identities = 46/170 (27%), Positives = 70/170 (41%), Gaps = 26/170 (15%)

Query: 144 KLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFH 203
           K D    HV    +E+  +E   SL    GG+   G L+K   N+      +++ RR+F 
Sbjct: 235 KRDMEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNA-----FKTWSRRWF- 288

Query: 204 LIQLGDGSYNLNFYKDEKISKEPKGSIF--LDSCMGVVQNNKVRRFAFELKMQDKSSYLL 261
            IQ     Y       +K  K+P   +   L  C   +  +  RRF FE+    KS  LL
Sbjct: 289 TIQSNQLVY-------QKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSC-LL 340

Query: 262 AADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSG 311
            ADSE  ++ W++ +   +   F  A            D+  +  G GSG
Sbjct: 341 QADSERLLQLWVSAVQSSIASAFSQARL----------DDSPRGPGQGSG 380


>gi|18105042 GRB2-associated binding protein 2 isoform a [Homo
           sapiens]
          Length = 676

 Score = 38.9 bits (89), Expect = 0.031
 Identities = 48/185 (25%), Positives = 89/185 (48%), Gaps = 29/185 (15%)

Query: 173 GGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYN---LNFYKDEKISKEPKGS 229
           G +   GWL K      +     ++K+R+F +++ G  S +   L +YK++  SK+P   
Sbjct: 5   GDVVCTGWLRKSPPEKKLR--RYAWKKRWF-ILRSGRMSGDPDVLEYYKNDH-SKKPLRI 60

Query: 230 IFLDSC----MGVVQNNKVRR--FAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283
           I L+ C     G+  N K  +  F F++K  +++ YL+ A++E +M +W+  + +I   N
Sbjct: 61  INLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV-AETEEDMNKWVQSICQICGFN 119

Query: 284 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKS-----ESRVKL 338
                Q + + DS  +     +  +G G  S   EL+ S++    + KS      S+  L
Sbjct: 120 -----QAEESTDSLRN-----VSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTL 169

Query: 339 FYLDP 343
           F  +P
Sbjct: 170 FTFEP 174


>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
          Length = 2390

 Score = 38.5 bits (88), Expect = 0.041
 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 14/127 (11%)

Query: 213  NLNFYKDEKISK-----EPKGSIFLDSCMGVVQ-NNKVRRFAFELKMQDKSSYLLAADSE 266
            +L FYKD K +        +  + L    G V  + + R+  F+L +QD   YL  A  E
Sbjct: 2254 SLGFYKDAKAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDE 2313

Query: 267  VEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREA 326
             EM  W+ ++N  +      A     +G+  E    S   G    +   +P ++    E 
Sbjct: 2314 AEMSSWLRVVNAAI------ATASSASGEPEEPVVPSTTRGMTRAMT--MPPVSPVGAEG 2365

Query: 327  EIKLKSE 333
             + L+S+
Sbjct: 2366 PVVLRSK 2372


>gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]
          Length = 359

 Score = 37.4 bits (85), Expect = 0.091
 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 22/138 (15%)

Query: 157 EEVDKDEDAASLGSQKGGIT--------KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLG 208
           E  DKD++A S G+Q   I         K G+L K   +   S     +++R+  L    
Sbjct: 91  ERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDH--SFLGFEWQKRWCAL---- 144

Query: 209 DGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRR-----FAFELKMQDKSSYLLAA 263
             S  + +Y      K+ KG   +D    V  NN +R+       FE+   DK  Y   A
Sbjct: 145 --SKTVFYYYGSDKDKQQKGEFAIDG-YSVRMNNTLRKDGKKDCCFEISAPDKRIYQFTA 201

Query: 264 DSEVEMEEWITILNKILQ 281
            S  + EEW+  L  +LQ
Sbjct: 202 ASPKDAEEWVQQLKFVLQ 219


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,313,432
Number of Sequences: 37866
Number of extensions: 2090516
Number of successful extensions: 5041
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 4916
Number of HSP's gapped (non-prelim): 127
length of query: 1254
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1140
effective length of database: 13,930,794
effective search space: 15881105160
effective search space used: 15881105160
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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