BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] (1254 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] 2523 0.0 gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 2480 0.0 gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens] 2444 0.0 gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 2401 0.0 gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] 1429 0.0 gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 1239 0.0 gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] 364 e-100 gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 273 8e-73 gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] 263 1e-69 gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 46 3e-04 gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 46 3e-04 gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 46 3e-04 gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 46 3e-04 gi|55741447 pleckstrin homology domain containing, family H (wit... 45 6e-04 gi|217416392 pleckstrin homology domain containing, family H (wi... 44 7e-04 gi|187608516 centaurin, beta 2 [Homo sapiens] 42 0.003 gi|24432056 hypothetical protein LOC144717 [Homo sapiens] 42 0.004 gi|5031805 insulin receptor substrate 1 [Homo sapiens] 41 0.008 gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 41 0.008 gi|238908495 similar to pleckstrin homology domain protein (5V32... 40 0.011 gi|219689123 pleckstrin homology domain containing, family A mem... 40 0.011 gi|19923493 pleckstrin homology domain containing, family A memb... 40 0.011 gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] 40 0.018 gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H... 40 0.018 gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H... 40 0.018 gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] 39 0.024 gi|7661880 centaurin beta1 [Homo sapiens] 39 0.024 gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sa... 39 0.031 gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 39 0.041 gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens] 37 0.091 >gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] Length = 1254 Score = 2523 bits (6540), Expect = 0.0 Identities = 1254/1254 (100%), Positives = 1254/1254 (100%) Query: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ Sbjct: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60 Query: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD Sbjct: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120 Query: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW Sbjct: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180 Query: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ Sbjct: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240 Query: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD Sbjct: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300 Query: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF Sbjct: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360 Query: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL Sbjct: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420 Query: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE Sbjct: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480 Query: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL Sbjct: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540 Query: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV Sbjct: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600 Query: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK Sbjct: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660 Query: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT Sbjct: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720 Query: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN Sbjct: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780 Query: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES Sbjct: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840 Query: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA Sbjct: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900 Query: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS Sbjct: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960 Query: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK Sbjct: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020 Query: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP Sbjct: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080 Query: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL Sbjct: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140 Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES Sbjct: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200 Query: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ 1254 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ Sbjct: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLLSTITLKVSWSQ 1254 >gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] Length = 2069 Score = 2480 bits (6427), Expect = 0.0 Identities = 1233/1235 (99%), Positives = 1234/1235 (99%) Query: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ Sbjct: 1 MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQ 60 Query: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD Sbjct: 61 KKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSD 120 Query: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW Sbjct: 121 WHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGW 180 Query: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ Sbjct: 181 LYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQ 240 Query: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD Sbjct: 241 NNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDD 300 Query: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF Sbjct: 301 EQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSF 360 Query: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL Sbjct: 361 EEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDL 420 Query: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE Sbjct: 421 NHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIE 480 Query: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL Sbjct: 481 KVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNL 540 Query: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV Sbjct: 541 DKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYV 600 Query: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK Sbjct: 601 NSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAK 660 Query: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT Sbjct: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720 Query: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN Sbjct: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSAN 780 Query: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES Sbjct: 781 LPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTES 840 Query: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA Sbjct: 841 GAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVA 900 Query: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS Sbjct: 901 QCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYS 960 Query: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK Sbjct: 961 WFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASK 1020 Query: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP Sbjct: 1021 NANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIP 1080 Query: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL Sbjct: 1081 LNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVL 1140 Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES Sbjct: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDES 1200 Query: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1235 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI + Sbjct: 1201 LALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1235 >gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens] Length = 1253 Score = 2444 bits (6335), Expect = 0.0 Identities = 1211/1211 (100%), Positives = 1211/1211 (100%) Query: 44 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE Sbjct: 43 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102 Query: 104 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE Sbjct: 103 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162 Query: 164 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS Sbjct: 163 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222 Query: 224 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN Sbjct: 223 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282 Query: 284 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP Sbjct: 283 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342 Query: 344 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL Sbjct: 343 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402 Query: 404 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI Sbjct: 403 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462 Query: 464 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM Sbjct: 463 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522 Query: 524 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG Sbjct: 523 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582 Query: 584 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL Sbjct: 583 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642 Query: 644 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH Sbjct: 643 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702 Query: 704 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL Sbjct: 703 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762 Query: 764 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT Sbjct: 763 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822 Query: 824 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT Sbjct: 823 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882 Query: 884 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI Sbjct: 883 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942 Query: 944 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM Sbjct: 943 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002 Query: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE Sbjct: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062 Query: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG Sbjct: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122 Query: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR Sbjct: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182 Query: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL 1243 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL Sbjct: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGNAPCSCGLL 1242 Query: 1244 STITLKVSWSQ 1254 STITLKVSWSQ Sbjct: 1243 STITLKVSWSQ 1253 >gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] Length = 2068 Score = 2401 bits (6222), Expect = 0.0 Identities = 1190/1192 (99%), Positives = 1191/1192 (99%) Query: 44 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 103 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE Sbjct: 43 AKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEE 102 Query: 104 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 163 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE Sbjct: 103 EAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDE 162 Query: 164 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 223 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS Sbjct: 163 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKIS 222 Query: 224 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN Sbjct: 223 KEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 282 Query: 284 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 343 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP Sbjct: 283 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP 342 Query: 344 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 403 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL Sbjct: 343 DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSL 402 Query: 404 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 463 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI Sbjct: 403 FDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGI 462 Query: 464 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 523 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM Sbjct: 463 FSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRM 522 Query: 524 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 583 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG Sbjct: 523 PFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILG 582 Query: 584 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL Sbjct: 583 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 642 Query: 644 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH Sbjct: 643 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 702 Query: 704 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL Sbjct: 703 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 762 Query: 764 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT Sbjct: 763 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 822 Query: 824 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 883 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT Sbjct: 823 QDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRAT 882 Query: 884 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 943 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI Sbjct: 883 QEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTI 942 Query: 944 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1003 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM Sbjct: 943 LKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNM 1002 Query: 1004 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1063 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE Sbjct: 1003 LMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFE 1062 Query: 1064 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1123 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG Sbjct: 1063 YKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVG 1122 Query: 1124 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1183 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR Sbjct: 1123 TALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVR 1182 Query: 1184 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIGN 1235 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGI + Sbjct: 1183 DVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIAS 1234 >gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] Length = 2073 Score = 1429 bits (3700), Expect = 0.0 Identities = 705/1186 (59%), Positives = 908/1186 (76%), Gaps = 14/1186 (1%) Query: 11 AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQKKTQILNDCL 70 AE RKFT+ LSKPGTAAELRQSVSE VRGSV+L K K++EPLDYENVI Q+KTQI +D L Sbjct: 2 AEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPL 61 Query: 71 REMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYED 130 R++L+FP +D +++ RQ R + STVP AE+ AQSLFV ECIKTY++DWH+VNYKYED Sbjct: 62 RDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYED 121 Query: 131 YSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAI 190 +SG+FR LP K ++ +K+P HV+E+DE+ +KDED++SL SQKGG+ K GWL+K N+NS I Sbjct: 122 FSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTI 181 Query: 191 SVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFE 250 +VTM+ FKRR+F+L QL DGSY LN YKDEK SKE KG I+LD+C+ VVQ K+RR AFE Sbjct: 182 TVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFE 241 Query: 251 LKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNG-DSHEDDE---QSKLE 306 LKM DK S+ LAA++E EMEEW+ L KI+Q+N ++ +QEK+ ++ +DDE Q K E Sbjct: 242 LKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAE 301 Query: 307 GSGSGLD-SYLPELAKSAREAEIKLK---SESRVKLFYLDPDAQKLDFSSAEPEVKSFEE 362 + L+ S PEL K RE E K + R LF D + Q+LDFS EP++K FEE Sbjct: 302 NIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEE 361 Query: 363 KFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNH 422 K KR LV C+DL+FN+ + +N +GP TNVEPFF+ L+LFD+K N KISADFHVDLN Sbjct: 362 KCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNP 421 Query: 423 FSVRQMLATTSPALMNGSGQSPSVLKGILH---EAAMQYPKQGIFSVTCPHPDIFLVARI 479 SVR+ML +S L + S + +H E+ ++Y +QGIFSVT PHP+IFLVARI Sbjct: 422 PSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARI 481 Query: 480 EKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGN 539 EKVLQG+ITHCAEPY+K+SD K AQKV + AKQ C RLGQYRMPFAWAAR +FKD G+ Sbjct: 482 EKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGS 541 Query: 540 LDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNY 599 LD + RFS +Y+QDS+KLS++D+LKLL++++KPEK KL +I G L+IT++ V D N Sbjct: 542 LDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEK-TKLQIIPGQLNITVECVPVDLSNC 600 Query: 600 VNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFA 659 + SSY+P K FE + IT EVEEFVP + K+ P+TIY NHLYVYP LKYDSQK+FA Sbjct: 601 ITSSYVPLKPFEKNCQN-ITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFA 659 Query: 660 KARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELP 719 KARNIA+C+EF+DSDE D+ LKCIYG+P G VFT +A+A V HH+QNPEFYDEIKIELP Sbjct: 660 KARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELP 719 Query: 720 TQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSA 779 LH+KHHLL TF+HVSC+ ++KG+TKK+D VET VG++W+PLLKDGR++T EQ +PVSA Sbjct: 720 IHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSA 779 Query: 780 NLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTE 839 NLP GYL + R +IKWVDG KPLLKI +HL ST+YTQD H+H FF +CQ + Sbjct: 780 NLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQ 839 Query: 840 SGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEE-VAVNVTRVIIHV 898 SG++ + EL+KYLK LHAME VMI FLP IL QLFRVLT T E+ V +N T V++H+ Sbjct: 840 SGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHI 899 Query: 899 VAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLK 958 V++CHEEGL+S+LRS++KY+++ E A + + +HE L +M ILK SADFL+ NKLLK Sbjct: 900 VSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLK 959 Query: 959 YSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEA 1018 YSWFFF+++ KSMA +L+E +K+KL R QRFP +YHH + +++ ++PH+T ++ + P+ Sbjct: 960 YSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDE 1019 Query: 1019 SKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHY 1078 S+N N+SLA F+KRC T MDRGF+F IN+YIS F+P DPK L EYKFEFL+ +CNHEHY Sbjct: 1020 SRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHY 1079 Query: 1079 IPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAIS 1138 IPLNLPM F K ++QR QD L+YSL+DE+C++HFLVGLLLRE ALQ+ E+R AIS Sbjct: 1080 IPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAIS 1139 Query: 1139 VLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRD 1184 V+KNLLIKH+FD RY ++ QA+IA LYLP GLL+EN+QR+ RD Sbjct: 1140 VIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRD 1185 >gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] Length = 2186 Score = 1239 bits (3207), Expect = 0.0 Identities = 638/1284 (49%), Positives = 893/1284 (69%), Gaps = 59/1284 (4%) Query: 9 ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLA------KPKLIEPLDYENVIVQKK 62 A TR+FTR+L +PG AAELR S + +V KP+L+EPLDYE VI + + Sbjct: 2 AGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELE 61 Query: 63 TQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWH 122 ND L+++L FP DDF A + R + STVP AE +A++L V E K Y+S WH Sbjct: 62 KTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWH 121 Query: 123 LVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVD-EEVDKDEDAASLGSQKGG------- 174 +VNYKYE YSG+ RQLP K +KLP H +E+D E+ DKDED S S KGG Sbjct: 122 VVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTG 181 Query: 175 ITKHGWLYKGNMNSAIS--VTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFL 232 + K GWLYKGN NS ++ VT+RSFK+R+F L QL D SY +NFYKDEKISKEPKG IFL Sbjct: 182 VFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFL 241 Query: 233 DSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKR 292 DSC GVVQNN++R++AFELKM D + ++LAA++E +M+EWI LN+ILQ++ E +Q +R Sbjct: 242 DSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRR 301 Query: 293 NG-------DSHEDDEQSKL--EGSGSGLDSYLPELAKSAREAEIKLKSE---SRVKLFY 340 + DS ++ + E + S ++ + AK E E +K+ R+ LF Sbjct: 302 STELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFS 361 Query: 341 LDPDA-----QKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVE 395 LDPD QK D E +K FEEK KRI++ C L+ NLQ CV ENE P TN+E Sbjct: 362 LDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIE 421 Query: 396 PFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGS--------GQSPSVL 447 PFFV+++L+D++ +RKISADFHVDLNH +VRQML S AL NG+ + P + Sbjct: 422 PFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHI- 480 Query: 448 KGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKV 507 KG L E +++PKQ +FSV+ PH +I LVA+IEKVL G+I AEPY+K+ DS+K AQK+ Sbjct: 481 KG-LPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKI 539 Query: 508 LKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLA 567 LK+ +Q C +LG+YRMPFAWA R++FKD GN+D+++RFS ++RQ+S+K+S +D++KL++ Sbjct: 540 LKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVS 599 Query: 568 DFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVP 627 D+R+ ++++K+ I G+LDI +DNV + PN V SS+IP K F ++T T EVEEFV Sbjct: 600 DYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVY 659 Query: 628 CIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGR 687 K+ +PY +Y N +Y+YPK+LKYDSQK F KARNI +CIEFK+SDEE ++PLKCIYG+ Sbjct: 660 DSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGK 719 Query: 688 PGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKK 747 PGGP+FT +A+ AVLHH QNP+F DE+KIELPTQLHEKHH+L +F+HV+CD ++K + KK Sbjct: 720 PGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKK 779 Query: 748 RDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGG 807 ++ +ET VGY+WLPL+K ++ + E +IP++ +LP YL +Q+ G+H G +IKWVDGG Sbjct: 780 KEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGG 839 Query: 808 KPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG-AQALGNELVKYLKSLHAMEG-HVMI 865 KPL K+ST +VSTV TQD H++ FFQ CQK E +Q+ + ++ K+L +E H ++ Sbjct: 840 KPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIM 899 Query: 866 AFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYV 925 +FLP ILNQLF+VL + ++E+ VTRV+ +VA+CHEE L+ ++SY+K+ +K Sbjct: 900 SFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTR--- 956 Query: 926 ASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLR 985 A + +TVHEEL K++T +LK S D T +LK+SWFFF +++KSMAQHLI+ +K++L R Sbjct: 957 ACKERTVHEELAKNVTGLLK-SNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPR 1015 Query: 986 NQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQ 1045 QRFP SY + ++ +V +L H+ K++D E ++ ANHS+A F+KRCFTFMDRG+VFK Sbjct: 1016 PQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKM 1075 Query: 1046 INNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-----MPFGKGRIQRYQDLQL 1100 +NNYIS F+ GD KTL +YKF+FL+ VC HEH+IPL LP +P + Q+L Sbjct: 1076 VNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHA 1135 Query: 1101 ----DYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKHSFDDRYASR 1156 +YS+T+EFCR HFL+G+LLREVG ALQE ++VR +A++VLKNL+ KHSFDDRY Sbjct: 1136 SDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREP 1195 Query: 1157 SHQARIATLYLPLFGLLIENVQRINVRDVSPFPVN-AGMTVKDESLALPAVNPLVTPQKG 1215 QA+IA+LY+PL+G+L++N+ RI ++D+ PF VN + +D+ + Sbjct: 1196 RKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHA 1255 Query: 1216 STLDNSLHKDLLGAISGIGNAPCS 1239 +++D S KD+L +I+ + S Sbjct: 1256 NSVDTSFSKDVLNSIAAFSSIAIS 1279 >gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] Length = 2047 Score = 364 bits (934), Expect = e-100 Identities = 304/1061 (28%), Positives = 473/1061 (44%), Gaps = 211/1061 (19%) Query: 285 EAAMQEKRNGDSHEDDEQSKLEGSGSGL-----DSYLPELAKSAREAEIKLKSES----- 334 E + +R S ED +S S L DS LP L + A ++ ++E+ Sbjct: 167 EDSNDSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQH 226 Query: 335 ---RVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPT 391 + Y PD + + PE E FG+RILVKC L F ++ Sbjct: 227 RPPALLTLYPAPDEDEAVERCSRPEPP--REHFGQRILVKCLSLKFEIE----------- 273 Query: 392 TNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGIL 451 +EP F L+L+D++ +KIS +F+ DLN S++ +L Sbjct: 274 --IEPIFGILALYDVREKKKISENFYFDLNSDSMKGLLRAHGT----------------- 314 Query: 452 HEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPYM--KSSDSSKVAQKVL 508 H A + IFSVT P PDIFLV ++EKVLQ G I+ C EPYM K D++K +K+ Sbjct: 315 HPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLE 374 Query: 509 K---NAKQACQRLGQYRMPFAWAARTLFK--DASGNLDKNA------------------- 544 K A+Q C RLG+YRMPFAW A L ++G LD+++ Sbjct: 375 KLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQ 434 Query: 545 ----------RFSAI----------YRQDSNKLSNDDMLKLLADFRKPEKMAK-LPVILG 583 FS ++Q++ +LS++D+ K LAD R+P + + L + Sbjct: 435 DRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTA 494 Query: 584 NLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHL 643 L I I + ++ + K + P T E+ EF P + P+T Y N L Sbjct: 495 QLKIDISPAPENPHFCLSPELLHIKPYPDPRGRP-TKEILEF-PAREVYA-PHTSYRNLL 551 Query: 644 YVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703 YVYP L + S++ RN+A+ +++ + E+ SQ L I+G+ FTR AF V++ Sbjct: 552 YVYPHSLNFSSRQG--SVRNLAVRVQYM-TGEDPSQALPVIFGKSSCSEFTREAFTPVVY 608 Query: 704 HHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL 763 H+++PEFY+E K+ LP + E HHLL TF+HVSC + +ET VG++W+PLL Sbjct: 609 HNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSC------QPRPGTALETPVGFTWIPLL 662 Query: 764 KDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYT 823 + GR+ T +PVS + P + P ++WVDG K + + VS+V+ Sbjct: 663 QHGRLRTGPFCLPVSVDQPPPSYSVLTPDVAL---PGMRWVDGHKGVFSVELTAVSSVHP 719 Query: 824 QDQHLHNFFQYCQKTESGA---------QALGN---ELVKYLKSLHAMEGHVMIAFLPTI 871 QD +L FF E GA + GN EL L +L ++AF + Sbjct: 720 QDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHV 779 Query: 872 LNQLFRVLTR-ATQEEVAVNVTR----VIIHVVAQCHE--------EGLESHLRSYVKYA 918 L++L R++ R VN+ R + HVV+ H G L +YV YA Sbjct: 780 LDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYA 839 Query: 919 YK----------AEPYVASEYKTVHEELTKSMTTILKPSADFLTSN-------------- 954 ++ P V + T+ + + L S +SN Sbjct: 840 FRLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEV 899 Query: 955 --------------------------KLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQR 988 +L+++WFFF +++KSMA HL+ ++ R R Sbjct: 900 SRILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLR 959 Query: 989 FPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINN 1048 FP + + +V + + + + E +++ N SLA F+ + +DRGFVF + Sbjct: 960 FPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRA 1019 Query: 1049 YISCFA-----PGDPKTLFEYKFEFLRVVCNHEHYIPLNLP-------------MPFGKG 1090 + A +P L + EF R++C+HEHY+ LNLP + Sbjct: 1020 HYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTS 1079 Query: 1091 RIQRYQDLQLD------YSLTDEFCRNHFLVGLLLREVGTALQEFREVRLI----AISVL 1140 + + D + L+ F + HFL GLLL E+ AL+ E + AIS + Sbjct: 1080 QSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAV 1139 Query: 1141 KNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRIN 1181 +LL H D RYA + +AR+A LYLPL + + + R++ Sbjct: 1140 HSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLH 1180 Score = 55.8 bits (133), Expect = 2e-07 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 16/165 (9%) Query: 9 ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAK----------PKLIEPLDYENVI 58 A++E R F +++ AAE+R+ VS GS ++ +++EPLD+E+V+ Sbjct: 2 AASERRAFAHKINRT-VAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVL 60 Query: 59 VQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYN 118 + + LR+++ FP DD + + R+ R +T P ++E V ++ Y Sbjct: 61 LSRPPDAEPGPLRDLVEFPADDLELLLQPRECR---TTEPGIPKDEKLDAQVRAAVEMYI 117 Query: 119 SDWHLVNYKYEDYSGEFRQLPNKVVKLDK--LPVHVYEVDEEVDK 161 DW +V+ +Y+ S + + + + LP V+E D D+ Sbjct: 118 EDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDE 162 >gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] Length = 2099 Score = 273 bits (698), Expect = 8e-73 Identities = 197/622 (31%), Positives = 302/622 (48%), Gaps = 110/622 (17%) Query: 324 REAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCV 383 ++ E ++ + +LF L P + D P + +E G RILVK L F ++ Sbjct: 224 KQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIE--- 280 Query: 384 AENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQS 443 +EP F +++L+D+K +KIS +FH DLN + L +P++ Sbjct: 281 ----------IEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSV------- 323 Query: 444 PSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ-GSITHCAEPY--MKSSDS 500 AA + +FSVT P DI+LV +IEKVLQ G I CAEPY +K SD Sbjct: 324 ----------AASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDG 373 Query: 501 SKVAQKVLKNAKQA---CQRLGQYRMPFAWAA---------------------------- 529 K +K+ K QA CQRLG+YRMPFAWA Sbjct: 374 GKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSV 433 Query: 530 ---RTL-----FKDASGNLDKNA----------RFSAIYRQDSNKLSNDDMLKLLADFRK 571 RTL + + +L++N S+ ++Q+ ++LS++D+ K LAD+++ Sbjct: 434 GERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKR 493 Query: 572 PEKMAK-LPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIP 630 + + + I G L + I + +P K F ++T E+ EF P Sbjct: 494 SSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPE-NRTRPHKEILEF-PTRE 551 Query: 631 KHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGG 690 + P+T+Y N LYVYP+ L + ++ A ARNI I I+F E+ S + I+G+ G Sbjct: 552 VYV-PHTVYRNLLYVYPQRLNFVNK--LASARNITIKIQFM-CGEDASNAMPVIFGKSSG 607 Query: 691 PVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDV 750 P F + + AV +H+++P+FY+E+KI+LP +L HHLL TF+H+SC S Sbjct: 608 PEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGAS------ 661 Query: 751 VETQVGYSWLPLLKDGRVVTSEQHIPVS-ANLPSGYLGYQELGMGRHYGPEIKWVDGGKP 809 VET +GYSWLP+L + R+ T +PV+ LP Y + + P IKW +G K Sbjct: 662 VETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQ-NPPIKWAEGHKG 720 Query: 810 LLKISTHLVSTVYTQDQHLHNFFQYCQKTES-------------GAQALGNELVKYLKSL 856 + I VS+V+TQD HL FF C ES AL +EL + L Sbjct: 721 VFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICL 780 Query: 857 HAMEGHVMIAFLPTILNQLFRV 878 ++ ++ FL +L++LF++ Sbjct: 781 NSSRLEPLVLFLHLVLDKLFQL 802 Score = 138 bits (348), Expect = 3e-32 Identities = 94/286 (32%), Positives = 143/286 (50%), Gaps = 32/286 (11%) Query: 921 AEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSK 980 A P AS+ K HEEL M + + + KY+WFFF++L+KSMAQH+ K Sbjct: 950 AAPRPASK-KHFHEELALQMVV-----STGMVRETVFKYAWFFFELLVKSMAQHVHNMDK 1003 Query: 981 VKLLRNQRFPASYHHAVETVVNMLMPHITQ---KFRDNPEASKNANHSLAVFIKRCFTFM 1037 R RF + + T+VN++ I K + E ++ N SLA F+ + M Sbjct: 1004 RDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLM 1063 Query: 1038 DRGFVFKQINNYISCFAP--GDPKTLFEYKFEFLRVVCNHEHYIPLNL-----------P 1084 DRGFVF I +Y S + + TL + EFLR++C+HEHY+ LNL P Sbjct: 1064 DRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSP 1123 Query: 1085 MPF----GKGRIQRYQDLQLD--YSLTDEFCRNHFLVGLLLREVGTAL----QEFREVRL 1134 P +QD ++ + LT E+ + HFL GLL E+ AL + +V+ Sbjct: 1124 CPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQR 1183 Query: 1135 IAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRI 1180 A+S + +LL H D R + +IA LYLPL G++++ + ++ Sbjct: 1184 KAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQL 1229 Score = 39.7 bits (91), Expect = 0.018 Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 18/169 (10%) Query: 9 ASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKL---IEPLDYENVIVQKKTQI 65 +SAE RK + P RQS+S G L P+ +EP+D+E +++ + Sbjct: 20 SSAEIRK--QFTLPPNLGQYHRQSIS--TSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSL 75 Query: 66 LNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSL--FVTECIKTYNSDWHL 123 +E+ F DD ++ C T+ EE L V +C++TY +W + Sbjct: 76 DVQLAQELGDFTDDDLDVVFTPKE----CRTLQPSLPEEGVELDPHVRDCVQTYIREWLI 131 Query: 124 VNYKYE---DYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLG 169 VN K + + G F++ ++ LP +E E ++ E AA G Sbjct: 132 VNRKNQGSPEICG-FKKTGSRKDFHKTLPKQTFE-SETLECSEPAAQAG 178 >gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] Length = 2109 Score = 263 bits (671), Expect = 1e-69 Identities = 206/698 (29%), Positives = 338/698 (48%), Gaps = 137/698 (19%) Query: 313 DSYLPELAKSAREAEI------KLKSESRVKLFYL--DPDAQKLDFSSAEPEVKSFEEKF 364 D+ LP L EI + KS +LF L PD ++ + P++ +E F Sbjct: 204 DALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDIP--KEHF 261 Query: 365 GKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFS 424 G+R+LVKC L F ++ +EP F +L+L+D+K +KIS +F+ DLN Sbjct: 262 GQRLLVKCLSLKFEIE-------------IEPIFASLALYDVKEKKKISENFYFDLNSEQ 308 Query: 425 VRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQ 484 ++ +L P P+ + + A IFS+T P D+FLV ++EKVLQ Sbjct: 309 MKGLLRPHVP---------PAAITTLARSA--------IFSITYPSQDVFLVIKLEKVLQ 351 Query: 485 -GSITHCAEPYM--KSSDSSKVAQKVLK---NAKQACQRLGQYRMPFAWAARTLFK--DA 536 G I CAEPYM K +D++K +K+ K A Q CQRLG+YRMPFAW A L + Sbjct: 352 QGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSS 411 Query: 537 SGNLDKNA-----------------RFSAI------------------------------ 549 +G+L++++ R S+I Sbjct: 412 AGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTN 471 Query: 550 -YRQDSNKLSNDDMLKLLADFRKPEK-MAKLPVILGNLDITIDNVSSDFPNYVNSSYIPT 607 ++Q+ ++LS++D+ K LAD R+P + +L I L I I + P+Y + + Sbjct: 472 FFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPEN-PHYCLTPELLQ 530 Query: 608 KQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAIC 667 + S+ T E+ EF P + P T Y N LY+YP+ L + +++ ARNI + Sbjct: 531 VKLYPDSRVRPTREILEF-PARDVYV-PNTTYRNLLYIYPQSLNFANRQG--SARNITVK 586 Query: 668 IEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHH 727 ++F E+ S + I+G+ F++ A+ AV++H+++P+F++EIK++LP L + HH Sbjct: 587 VQFMYG-EDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHH 645 Query: 728 LLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLG 787 LL TF+HVSC K+ +ET VGY+W+P+L++GR+ T + +PVS P Sbjct: 646 LLFTFYHVSCQQ------KQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPP--QA 697 Query: 788 YQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG------ 841 Y L P +KWVD K + + VS+++TQD +L FF + Sbjct: 698 YSVLSPEVPL-PGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHLFPVRI 756 Query: 842 ------AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTR-------------A 882 L NEL + +L++ + ++ FL +L++L ++ R A Sbjct: 757 GDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQA 816 Query: 883 TQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920 + E +A + R+ ++ + G S L SY+ Y ++ Sbjct: 817 SFEAMASIINRLHKNLEGNHDQHGRNSLLASYIHYVFR 854 Score = 136 bits (343), Expect = 1e-31 Identities = 80/254 (31%), Positives = 132/254 (51%), Gaps = 32/254 (12%) Query: 957 LKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNP 1016 L+ +WFFF++++KSM HL N K++ R RFP + + +V+ + I +F+ + Sbjct: 974 LQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPERFMDDIAALVSTIASDIVSRFQKDT 1033 Query: 1017 EASKNANHSLAVFIKRCFTFMDRGFVF-------KQINNYISCFAPGDPKTLFEYKFEFL 1069 E + N SLA F+ + MDRGFVF KQ+++ + ++ +P L + +FL Sbjct: 1034 EMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSSKL--YSLPNPSVLVSLRLDFL 1091 Query: 1070 RVVCNHEHYIPLNLPMPF-----------------GKGRIQRYQDLQLD--YSLTDEFCR 1110 R++C+HEHY+ LNLP G QD ++ + L+ F + Sbjct: 1092 RIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQ 1151 Query: 1111 NHFLVGLLLREVGTALQEFRE----VRLIAISVLKNLLIKHSFDDRYASRSHQARIATLY 1166 H+L GL+L E+ L E + I+++ NLL H D RY+ +AR+A LY Sbjct: 1152 QHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLY 1211 Query: 1167 LPLFGLLIENVQRI 1180 LPL G+++E V ++ Sbjct: 1212 LPLIGIIMETVPQL 1225 Score = 64.7 bits (156), Expect = 5e-10 Identities = 50/170 (29%), Positives = 77/170 (45%), Gaps = 26/170 (15%) Query: 11 AETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAK----------------PKLIEPLDY 54 AE R F + +S+ AAE+R+ +S GS L K + ++P+D Sbjct: 2 AERRAFAQKISRT-VAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDL 60 Query: 55 ENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECI 114 E+ ++ + + LR+++ FP DD + R R + S VP EE V +CI Sbjct: 61 EDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVP---EESEMDPHVRDCI 117 Query: 115 KTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDK----LPVHVYEVDEEVD 160 ++Y DW +V KY F PN + K + LP V+E DE D Sbjct: 118 RSYTEDWAIVIRKYHKLGTGFN--PNTLDKQKERQKGLPKQVFESDEAPD 165 >gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] Length = 1966 Score = 45.8 bits (107), Expect = 3e-04 Identities = 55/248 (22%), Positives = 102/248 (41%), Gaps = 31/248 (12%) Query: 661 ARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPT 720 ARN+ + + DS Q LK G + VL+H+ +P + + +K+ +P Sbjct: 421 ARNVEVTMFIVDSS---GQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPV 477 Query: 721 QLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLL-KDGRVVTSEQHIPV-- 777 H+ F H C KG K G+S++PL+ +DGR + H + Sbjct: 478 DKFRGAHIRFEFRH--CSTKEKGEKK-------LFGFSFVPLMQEDGRTLPDGTHELIVH 528 Query: 778 ----SANL--PSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNF 831 + NL + YL G G + + K I++ L ST TQ+ + + Sbjct: 529 KCEENTNLQDTTRYLKL-PFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDL 587 Query: 832 FQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNV 891 ++ + +++ L L ++G ++ FL L+ LF +L +Q + V Sbjct: 588 LKW--------RTHPDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDENSQ-KYGSKV 638 Query: 892 TRVIIHVV 899 ++H++ Sbjct: 639 FDSLVHII 646 >gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] Length = 1865 Score = 45.8 bits (107), Expect = 3e-04 Identities = 75/342 (21%), Positives = 146/342 (42%), Gaps = 43/342 (12%) Query: 645 VYPKYLKYDSQK-SFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLH 703 +Y ++ D K S A+N+ + + D ED + L+ + PG S + +V++ Sbjct: 428 IYVTLVQGDFDKGSKTTAKNVEVTVSVYD---EDGKRLEHVIF-PGAGDEAISEYKSVIY 483 Query: 704 HH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPL 762 + + P +++ +K+ +P + + HL TF H S +S S K + ++ Sbjct: 484 YQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTT 543 Query: 763 LKDGR----VVTSE----QHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDG---GKPLL 811 L+DG V +E + +LPS +E G G ++ + K Sbjct: 544 LRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSA-TGKSMQSLGSCTISKDSF 602 Query: 812 KISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTI 871 +IST + ST TQ+ L ++ T + L + L+ L ++G ++ FL Sbjct: 603 QISTLVCSTKLTQNVDLLGLLKWRSNT--------SLLQQNLRQLMKVDGGEVVKFLQDT 654 Query: 872 LNQLFRVLTRATQEE----VAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKA------ 921 L+ LF ++ ++ E + + II ++A + L +Y+K + A Sbjct: 655 LDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTK 714 Query: 922 -----EPYV-ASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957 + YV +E V+E+L K+M L+ F+ +++L Sbjct: 715 LTKVLKNYVDGAEKPGVNEQLYKAMKA-LESIFKFIVRSRIL 755 >gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sapiens] Length = 645 Score = 45.8 bits (107), Expect = 3e-04 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%) Query: 177 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 236 K GWL K ++++++R+F L + L +YKDE+ +K P+G ++L C Sbjct: 49 KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 96 Query: 237 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 279 + N + +F FE+ + SY+L A S+ EMEEW+ L ++ Sbjct: 97 IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 149 >gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapiens] Length = 638 Score = 45.8 bits (107), Expect = 3e-04 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 22/113 (19%) Query: 177 KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCM 236 K GWL K ++++++R+F L + L +YKDE+ +K P+G ++L C Sbjct: 42 KMGWLKKQRS------IVKNWQQRYFVL-----RAQQLYYYKDEEDTK-PQGCMYLPGCT 89 Query: 237 --GVVQN-NKVRRFAFEL-------KMQDKSSYLLAADSEVEMEEWITILNKI 279 + N + +F FE+ + SY+L A S+ EMEEW+ L ++ Sbjct: 90 IKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRV 142 >gi|55741447 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 [Homo sapiens] Length = 1364 Score = 44.7 bits (104), Expect = 6e-04 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 17/120 (14%) Query: 164 DAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEK-I 222 D LG + + K G+L K M S + +++KRR+F L Q + +YK + Sbjct: 570 DGLGLGGES--LEKSGYLLK--MGSQV----KTWKRRWFVLRQ-----GQIMYYKSPSDV 616 Query: 223 SKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQL 282 ++P+G + L+S +V+ + F + +K +Y L ADS +EEWI +L +L++ Sbjct: 617 IRKPQGQVDLNSRCQIVRGEGSQTFQL---ISEKKTYYLTADSPSLLEEWIRVLQSLLKV 673 >gi|217416392 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 [Homo sapiens] Length = 1493 Score = 44.3 bits (103), Expect = 7e-04 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 20/142 (14%) Query: 148 LPVHVYEVDEEVDKDED-------AASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRR 200 +P Y D E + E ++S + + K G+L K +S ++S+KRR Sbjct: 670 IPPDAYSTDTEYSQPEQKLPKTCSSSSDNGKNEPLEKSGYLLK------MSGKVKSWKRR 723 Query: 201 FFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYL 260 +F L G L + + ++P+G I L + +++ + + +K +Y Sbjct: 724 WFVL----KGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNKQTVQLTT---EKHTYY 776 Query: 261 LAADSEVEMEEWITILNKILQL 282 L ADS +EEWI +L +L++ Sbjct: 777 LTADSPNILEEWIKVLQNVLRV 798 >gi|187608516 centaurin, beta 2 [Homo sapiens] Length = 778 Score = 42.4 bits (98), Expect = 0.003 Identities = 60/225 (26%), Positives = 95/225 (42%), Gaps = 35/225 (15%) Query: 156 DEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLN 215 D +++ + DAA+ GI G+L+K N+ +++ RR+F IQ Y Sbjct: 254 DSKLEYNVDAAN------GIVMEGYLFKRASNA-----FKTWNRRWFS-IQNNQLVYQKK 301 Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITI 275 F + + E + C + RRF FE+ KS +L ADSE + WI Sbjct: 302 FKDNPTVVVEDLRLCTVKHCEDIE-----RRFCFEVVSPTKSC-MLQADSEKLRQAWI-- 353 Query: 276 LNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESR 335 K +Q + A +EK GD E ++ +GS LDS E LK ES Sbjct: 354 --KAVQTSIATAYREK--GDESEKLDKKSSPSTGS-LDS-------GNESKEKLLKGESA 401 Query: 336 VKLFYLDP-DAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNL 379 ++ P +A D A+P S G + ++C+ + +L Sbjct: 402 LQRVQCIPGNASCCDCGLADPRWASI--NLGITLCIECSGIHRSL 444 >gi|24432056 hypothetical protein LOC144717 [Homo sapiens] Length = 249 Score = 42.0 bits (97), Expect = 0.004 Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 13/101 (12%) Query: 179 GWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSC-MG 237 G+LYK A ++ RR+F L N+ FY ++ S+EP G I L+ C + Sbjct: 22 GFLYKKGGRHA------AYHRRWFVL------RGNMLFYFEDAASREPVGVIILEGCTVE 69 Query: 238 VVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNK 278 +V+ + FA +Y+LAA+S+ ME W+ L++ Sbjct: 70 LVEAAEEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSR 110 >gi|5031805 insulin receptor substrate 1 [Homo sapiens] Length = 1242 Score = 40.8 bits (94), Expect = 0.008 Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 17/123 (13%) Query: 195 RSFKRRFFHLIQLGD--GSYNLNFYKDEKI----SKEPKGSIFLDSCMGVVQNNKVRRFA 248 +S +RFF L + G L +Y++EK S PK SI L+SC + + + Sbjct: 23 KSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKH 82 Query: 249 FELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGS 308 + +AADSE E + W ++A +Q H D + G Sbjct: 83 LVALYTRDEHFAIAADSEAEQDSW-----------YQALLQLHNRAKGHHDGAAALGAGG 131 Query: 309 GSG 311 G G Sbjct: 132 GGG 134 >gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] Length = 1870 Score = 40.8 bits (94), Expect = 0.008 Identities = 72/350 (20%), Positives = 139/350 (39%), Gaps = 53/350 (15%) Query: 641 NHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAA 700 N +YV + ++D K +N+ + + D EE K I+ PG S + + Sbjct: 444 NDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHD--EEGKLLEKAIH--PGAGYEGISEYKS 498 Query: 701 VLHHH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSW 759 V+++ + P +Y+ +K+ + + + H+ TF H + S + RD E G ++ Sbjct: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551 Query: 760 LPLLK-DGRVVTSEQHIPV--------------SANLPSGYLGYQ--ELGMGRHYGPEIK 802 + L+ DG + +H V LP + + EL ++ Sbjct: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611 Query: 803 WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGH 862 D K +I+T + ST TQ+ L + +++ + LK L ++G Sbjct: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQN--------IKHNLKKLMEVDGG 663 Query: 863 VMIAFLPTILNQLFRVLTRATQEE--------VAVNVTRVIIHVVAQCHEEGLESHL--- 911 ++ FL L+ LF ++ + E V + +I + Q LE+++ Sbjct: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723 Query: 912 ----RSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957 +YVK + YVA+ + EL + LK F+ +++L Sbjct: 724 FSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVL 773 >gi|238908495 similar to pleckstrin homology domain protein (5V327) [Homo sapiens] Length = 506 Score = 40.4 bits (93), Expect = 0.011 Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%) Query: 197 FKRRFFHLIQLGDGSYNLNFYKDEKISKE--------PKGSIFLDSCMGVVQNNKVRRFA 248 + RRFF + + S+ L + + EK S E PKG I L C+ + +A Sbjct: 47 WSRRFFIIKE----SFLLYYSESEKKSFETNKYFNIHPKGVIPLGGCLVEPKEEPSMPYA 102 Query: 249 FELKMQD-KSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEG 307 ++ QD + LLAA+SE E +W+ +L + ++ ++ A + S E + Sbjct: 103 MKISHQDFHGNILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKE 162 Query: 308 SGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDP--DAQKLDFSSAEPEVKSFEEKFG 365 LD + E E+ L+ E R +L L+ +A+K F E++ +E+ Sbjct: 163 KQEYLDKLMEE------TEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIK 216 Query: 366 KRI 368 + + Sbjct: 217 REL 219 Score = 30.8 bits (68), Expect = 8.5 Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 11/99 (11%) Query: 275 ILNKILQLNFEAAMQEKRNGDSHE-----DDEQSKLEGSGSGLDSYLPELAKSAREAEIK 329 I K+ QL E + EKR ++ E ++E+ L + L EL ++AE + Sbjct: 291 IEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTAEKQQAERE 350 Query: 330 LKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRI 368 LK+E +V++ D ++ AE ++S E+ ++ Sbjct: 351 LKAEVKVRM-----DLER-RLREAEGALRSLEQGLNSKV 383 >gi|219689123 pleckstrin homology domain containing, family A member 5 isoform 2 [Homo sapiens] Length = 1105 Score = 40.4 bits (93), Expect = 0.011 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%) Query: 175 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 234 + + GWLYK + S M+ +K+R+F L L L +Y+DEK + GSI L S Sbjct: 62 VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 110 Query: 235 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 273 + +++ R++AF+ + +Y D+ EME W+ Sbjct: 111 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 152 >gi|19923493 pleckstrin homology domain containing, family A member 5 isoform 1 [Homo sapiens] Length = 1116 Score = 40.4 bits (93), Expect = 0.011 Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 14/102 (13%) Query: 175 ITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDS 234 + + GWLYK + S M+ +K+R+F L L L +Y+DEK + GSI L S Sbjct: 170 VVRRGWLYKQD-----STGMKLWKKRWFVLSDLC-----LFYYRDEK-EEGILGSILLPS 218 Query: 235 ---CMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWI 273 + +++ R++AF+ + +Y D+ EME W+ Sbjct: 219 FQIALLTSEDHINRKYAFKAAHPNMRTYYFCTDTGKEMELWM 260 >gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] Length = 2030 Score = 39.7 bits (91), Expect = 0.018 Identities = 57/224 (25%), Positives = 93/224 (41%), Gaps = 34/224 (15%) Query: 677 DSQPLK-CIYGRPGGPVFTRSAFAA-VLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFH 734 D + LK CI G P RS++ + VL+H +P + + IK+ +P HL F H Sbjct: 454 DGEILKDCISLGSGEP--NRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRH 511 Query: 735 VSCDNSSKGSTKKRDVVETQVGYSWLPLLK-DGRVVTSEQH--------IPVSANLPSGY 785 C KG K G+++ L++ DG ++ + H + N + Y Sbjct: 512 --CSTKDKGEKK-------LFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALY 562 Query: 786 LGYQELGMGRHYGPEIK----WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESG 841 LG + P I + K IST L ST TQ+ L ++ Sbjct: 563 LGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKW------- 615 Query: 842 AQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQE 885 +A + ++ L L + G ++ FL IL+ LF +L T++ Sbjct: 616 -KAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDDNTEK 658 >gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo sapiens] Length = 358 Score = 39.7 bits (91), Expect = 0.018 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%) Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 270 +Y +EK SK+PKG+ FL GV +RR + FEL QD+ SY A S E Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199 Query: 271 EWITILNKILQ------LNFEAAMQEKRNGDSHED 299 +W+ ++ +L+ + +E +E+ ++++D Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234 >gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo sapiens] Length = 359 Score = 39.7 bits (91), Expect = 0.018 Identities = 29/95 (30%), Positives = 50/95 (52%), Gaps = 13/95 (13%) Query: 216 FYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFA-----FELKMQDKSSYLLAADSEVEME 270 +Y +EK SK+PKG+ FL GV +RR + FEL QD+ SY A S E Sbjct: 142 YYANEK-SKQPKGT-FLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEAR 199 Query: 271 EWITILNKILQ------LNFEAAMQEKRNGDSHED 299 +W+ ++ +L+ + +E +E+ ++++D Sbjct: 200 DWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDD 234 >gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] Length = 1830 Score = 39.3 bits (90), Expect = 0.024 Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%) Query: 699 AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 758 + V + + P + + +K+ +P + ++ HL F H + S + +D E S Sbjct: 478 SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530 Query: 759 WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 805 ++ L+K DG + H V S + Y L RH+ V Sbjct: 531 YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590 Query: 806 G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 861 G + + IST + ST TQ+ L ++ K + L + L+ L ++G Sbjct: 591 GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642 Query: 862 HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920 ++ FL L+ LF ++ +Q +E + V +I+++ + R + + Sbjct: 643 EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695 Query: 921 AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 972 E Y+ + +++L + T L S+ L + K L+Y F F V +++ Sbjct: 696 LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754 Query: 973 QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1004 L E + F S E++ N++ Sbjct: 755 SQLYEGKE-----QMEFEESMRRLFESINNLM 781 >gi|7661880 centaurin beta1 [Homo sapiens] Length = 740 Score = 39.3 bits (90), Expect = 0.024 Identities = 46/170 (27%), Positives = 70/170 (41%), Gaps = 26/170 (15%) Query: 144 KLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFH 203 K D HV +E+ +E SL GG+ G L+K N+ +++ RR+F Sbjct: 235 KRDMEQRHVLLKQKELGGEEPEPSLREGPGGLVMEGHLFKRASNA-----FKTWSRRWF- 288 Query: 204 LIQLGDGSYNLNFYKDEKISKEPKGSIF--LDSCMGVVQNNKVRRFAFELKMQDKSSYLL 261 IQ Y +K K+P + L C + + RRF FE+ KS LL Sbjct: 289 TIQSNQLVY-------QKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSC-LL 340 Query: 262 AADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSG 311 ADSE ++ W++ + + F A D+ + G GSG Sbjct: 341 QADSERLLQLWVSAVQSSIASAFSQARL----------DDSPRGPGQGSG 380 >gi|18105042 GRB2-associated binding protein 2 isoform a [Homo sapiens] Length = 676 Score = 38.9 bits (89), Expect = 0.031 Identities = 48/185 (25%), Positives = 89/185 (48%), Gaps = 29/185 (15%) Query: 173 GGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYN---LNFYKDEKISKEPKGS 229 G + GWL K + ++K+R+F +++ G S + L +YK++ SK+P Sbjct: 5 GDVVCTGWLRKSPPEKKLR--RYAWKKRWF-ILRSGRMSGDPDVLEYYKNDH-SKKPLRI 60 Query: 230 IFLDSC----MGVVQNNKVRR--FAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLN 283 I L+ C G+ N K + F F++K +++ YL+ A++E +M +W+ + +I N Sbjct: 61 INLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLV-AETEEDMNKWVQSICQICGFN 119 Query: 284 FEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKS-----ESRVKL 338 Q + + DS + + +G G S EL+ S++ + KS S+ L Sbjct: 120 -----QAEESTDSLRN-----VSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTL 169 Query: 339 FYLDP 343 F +P Sbjct: 170 FTFEP 174 >gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] Length = 2390 Score = 38.5 bits (88), Expect = 0.041 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 14/127 (11%) Query: 213 NLNFYKDEKISK-----EPKGSIFLDSCMGVVQ-NNKVRRFAFELKMQDKSSYLLAADSE 266 +L FYKD K + + + L G V + + R+ F+L +QD YL A E Sbjct: 2254 SLGFYKDAKAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDE 2313 Query: 267 VEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREA 326 EM W+ ++N + A +G+ E S G + +P ++ E Sbjct: 2314 AEMSSWLRVVNAAI------ATASSASGEPEEPVVPSTTRGMTRAMT--MPPVSPVGAEG 2365 Query: 327 EIKLKSE 333 + L+S+ Sbjct: 2366 PVVLRSK 2372 >gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens] Length = 359 Score = 37.4 bits (85), Expect = 0.091 Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 22/138 (15%) Query: 157 EEVDKDEDAASLGSQKGGIT--------KHGWLYKGNMNSAISVTMRSFKRRFFHLIQLG 208 E DKD++A S G+Q I K G+L K + S +++R+ L Sbjct: 91 ERYDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKDH--SFLGFEWQKRWCAL---- 144 Query: 209 DGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRR-----FAFELKMQDKSSYLLAA 263 S + +Y K+ KG +D V NN +R+ FE+ DK Y A Sbjct: 145 --SKTVFYYYGSDKDKQQKGEFAIDG-YSVRMNNTLRKDGKKDCCFEISAPDKRIYQFTA 201 Query: 264 DSEVEMEEWITILNKILQ 281 S + EEW+ L +LQ Sbjct: 202 ASPKDAEEWVQQLKFVLQ 219 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 46,313,432 Number of Sequences: 37866 Number of extensions: 2090516 Number of successful extensions: 5041 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 19 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 4916 Number of HSP's gapped (non-prelim): 127 length of query: 1254 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1140 effective length of database: 13,930,794 effective search space: 15881105160 effective search space used: 15881105160 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.