Search of human proteins with 193083178

Search of human proteins with 193083178

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|193083178 cytochrome P450 family 4 subfamily F polypeptide
11 [Homo sapiens]
         (524 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11...  1091   0.0  
gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11...  1091   0.0  
gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide ...   951   0.0  
gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide...   916   0.0  
gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide...   902   0.0  
gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8...   865   0.0  
gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide...   689   0.0  
gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide...   414   e-115
gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide...   412   e-115
gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide...   411   e-115
gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide ...   410   e-114
gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide ...   387   e-107
gi|30023836 cytochrome P450 4Z1 [Homo sapiens]                        381   e-105
gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide...   280   2e-75
gi|239757171 PREDICTED: similar to cytochrome P450, family 4, su...   248   7e-66
gi|239751683 PREDICTED: similar to cytochrome P450, family 4, su...   248   7e-66
gi|239746187 PREDICTED: similar to cytochrome P450, family 4, su...   248   7e-66
gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide ...   155   9e-38
gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7...   154   1e-37
gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide ...   152   6e-37
gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide ...   151   2e-36
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5...   144   2e-34
gi|5729796 cytochrome P450, family 46 [Homo sapiens]                  124   3e-28
gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide ...   117   2e-26
gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1 ...   113   4e-25
gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [H...   105   8e-23
gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [H...   105   8e-23
gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide ...   102   1e-21
gi|190570174 cytochrome P450, family 21, subfamily A, polypeptid...   100   2e-21
gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide ...   100   2e-21

>gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 524/524 (100%), Positives = 524/524 (100%)

Query: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60
           MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF
Sbjct: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60

Query: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120
           WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK
Sbjct: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120

Query: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180
           DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR
Sbjct: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240
           LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240

Query: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300
           LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID
Sbjct: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360
           VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE
Sbjct: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360

Query: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420
           LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC
Sbjct: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420

Query: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ 524
           VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ
Sbjct: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ 524


>gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 524/524 (100%), Positives = 524/524 (100%)

Query: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60
           MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF
Sbjct: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60

Query: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120
           WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK
Sbjct: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120

Query: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180
           DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR
Sbjct: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240
           LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240

Query: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300
           LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID
Sbjct: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360
           VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE
Sbjct: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360

Query: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420
           LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC
Sbjct: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420

Query: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ 524
           VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ
Sbjct: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ 524


>gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide 2
           [Homo sapiens]
          Length = 520

 Score =  951 bits (2459), Expect = 0.0
 Identities = 452/519 (87%), Positives = 480/519 (92%)

Query: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60
           M QLSLSWLGL PVAASPWLLLLLVG SWLLA VLAWTY FYDNCRRL+CFPQPP++NWF
Sbjct: 1   MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF 60

Query: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120
           WGHQG+V PTEEGM+ LTQLV TYPQGFK+W+GP  PLL LCHPDIIR + +ASAA+APK
Sbjct: 61  WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK 120

Query: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180
           D  FY FL+PWLGDGLLLS GDKWSRHRRMLTPAFHFNILKPYMKIFN+SVNIMH KWQ 
Sbjct: 121 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240
           LASEGSA LDMFEHISLMTLDSLQKCVFSF+S+CQEKPSEYIAAILELSA V KR+ +IL
Sbjct: 181 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL 240

Query: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300
           LH DFLYYLTPDGQRFRRAC LVHDFTDAVIQERR TLP+QG+DDFL+ KAKSKTLDFID
Sbjct: 241 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360
           VLLLSKDEDGK+LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQE+CRQEVQE
Sbjct: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360

Query: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420
           LLKDREP EIEWDDLA LPFLTMC+KESLRLHPPVPVISR  TQD VLPDGRVIPKGI+C
Sbjct: 361 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC 420

Query: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LI++ G H+NP VWPDPEVYDPFRFD ENIKERSPLAFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV 480

Query: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPL 519
           VLALTLL FR+LP HTEPRRKPEL+LRAEGGLWLRVEPL
Sbjct: 481 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519


>gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide 12
           [Homo sapiens]
          Length = 524

 Score =  916 bits (2368), Expect = 0.0
 Identities = 435/524 (83%), Positives = 469/524 (89%)

Query: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60
           M  LSL WLGL PVA SPWLLLLLV GSWLLAR+LAWTY FY+NCRRLQCFPQPPK+NWF
Sbjct: 1   MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF 60

Query: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120
           WGH GL+TPTEEG+K  TQ+  TY QGF +WLGP  P ++LCHPD IR IT+ASAA+APK
Sbjct: 61  WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK 120

Query: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180
           D +F  FLKPWLG+G+LLSGGDKWSRHRRMLTPAFHFNILK Y+ IFNKS NIM DKWQ 
Sbjct: 121 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240
           LASEGS+RLDMFEHISLMTLDSLQKC+FSF+S+CQE+PSEYIA ILELSA VEKR+Q IL
Sbjct: 181 LASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL 240

Query: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300
            H DFLYYL+ DG+RF RAC LVHDFTDAVI+ERR TLPTQGIDDF K+KAKSKTLDFID
Sbjct: 241 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360
           VLLLSKDEDGK LSDEDIRAEADTFMF GHDTTASGLSWVLY+LA+HPEYQE+CRQEVQE
Sbjct: 301 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE 360

Query: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420
           LLKDR+P EIEWDDLAQLPFLTMC+KESLRLHPP P ISRCCTQD VLPDGRVIPKGI C
Sbjct: 361 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC 420

Query: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LI+IIG+H+NPTVWPDPEVYDPFRFD EN K RSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ 524
           VLAL LLHFR LP HTEPRRK ELI+RAEGGLWLRVEPL    Q
Sbjct: 481 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVGLQ 524


>gi|119220562 cytochrome P450, family 4, subfamily F, polypeptide 3
           [Homo sapiens]
          Length = 520

 Score =  902 bits (2331), Expect = 0.0
 Identities = 431/519 (83%), Positives = 466/519 (89%)

Query: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60
           MPQLSLS LGL P+AASPWLLLLLVG SWLLAR+LAWTYTFYDNC RL+CFPQPPK+NWF
Sbjct: 1   MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF 60

Query: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120
            GH GL+  +EEG+     L  T+      W+GP   ++ + HP  I+P+  A AA+ PK
Sbjct: 61  LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK 120

Query: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180
           D +FY FLKPWLGDGLLLS G+KWSRHRRMLTPAFHFNILKPYMKIFN+SVNIMH KWQ 
Sbjct: 121 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240
           LASEGSARLDMFEHISLMTLDSLQKCVFSF+S+CQEKPSEYIAAILELSA V KR+QQIL
Sbjct: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL 240

Query: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300
           L+ DFLYYLTPDGQRFRRAC LVHDFTDAVIQERR TLP+QG+DDFL+ KAKSKTLDFID
Sbjct: 241 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360
           VLLLSKDEDGK+LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQE+CRQEVQE
Sbjct: 301 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE 360

Query: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420
           LLKDREP EIEWDDLAQLPFLTMCIKESLRLHPPVP +SRCCTQD VLPDGRVIPKGI+C
Sbjct: 361 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC 420

Query: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
           LI++ G H+NP VWPDPEVYDPFRFD +NIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
Sbjct: 421 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480

Query: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPL 519
           VL LTLL FR+LP HTEPRRKPEL+LRAEGGLWLRVEPL
Sbjct: 481 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPL 519


>gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8
           [Homo sapiens]
          Length = 520

 Score =  865 bits (2236), Expect = 0.0
 Identities = 412/520 (79%), Positives = 454/520 (87%)

Query: 1   MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF 60
           M  LSLSWLGL PVAASPWLLLL+VG SWLLAR+LAWTY FY N RRL+CFPQP KQNWF
Sbjct: 1   MSLLSLSWLGLRPVAASPWLLLLVVGASWLLARILAWTYAFYHNGRRLRCFPQPRKQNWF 60

Query: 61  WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK 120
            GH GLVTPTEEG++ LTQLV TYPQGF  WLGP  P++ LCHPDI+R + + S A+  K
Sbjct: 61  LGHLGLVTPTEEGLRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDK 120

Query: 121 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR 180
           D++FY  LKPWLGDGLLLS GDKW  HRR+LTPAFHFNILKPY+KIF+KS NIMH KWQR
Sbjct: 121 DIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQR 180

Query: 181 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL 240
           LA EGS  LD+FEHISLMTLDSLQKC+FSF+SNCQEKPSEYI AI+ELSA V KRN Q  
Sbjct: 181 LAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFF 240

Query: 241 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID 300
            + DFLY+LTP G+RF RAC LVHDFTDAVIQERR TL +QG+DDFL+ KAKSKTLDFID
Sbjct: 241 RYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFID 300

Query: 301 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE 360
           VLLLS+D++GKELSDEDIRAEADTFMF GHDTTASGLSWVLY+LA+HPEYQE+CRQEVQE
Sbjct: 301 VLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE 360

Query: 361 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC 420
           LLKDREP EIEWDDLAQLPFLTMC+KESLRLHPP+P  +R CTQD VLPD RVIPKG VC
Sbjct: 361 LLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVC 420

Query: 421 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV 480
            INI  IH+NP+VWPDPEVYDPFRFD EN ++RSP+AFIPFSAGPRNCIGQ FAMAEMKV
Sbjct: 421 NINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKV 480

Query: 481 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLG 520
           VLALTLL FRILP H EPRR PE++LRAE GLWLRVEPLG
Sbjct: 481 VLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVEPLG 520


>gi|158138530 cytochrome P450, family 4, subfamily F, polypeptide 22
           [Homo sapiens]
          Length = 531

 Score =  689 bits (1777), Expect = 0.0
 Identities = 329/506 (65%), Positives = 406/506 (80%), Gaps = 2/506 (0%)

Query: 15  AASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEEGM 74
           A S  LL LL     LL R L    +FY  CRRL+CFPQPP++NW  GH G+  P E G+
Sbjct: 23  AVSTLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQPPRRNWLLGHLGMYLPNEAGL 82

Query: 75  KTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGD 134
           +   +++        +W+GP  PLL+L HPD I+P+  ASAA+APKD +FYGFLKPWLGD
Sbjct: 83  QDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGD 142

Query: 135 GLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEH 194
           GLLLS GDKWSRHRR+LTPAFHF+ILKPYMKIFN+S +IMH KW+ LA   +  LDMFEH
Sbjct: 143 GLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLAEGSAVSLDMFEH 202

Query: 195 ISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQ 254
           ISLMTLDSLQKCVFS+ SNCQEK S+YI+AI+ELSA   +R  ++  + DF+YY + DG+
Sbjct: 203 ISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSADGR 262

Query: 255 RFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELS 314
           RFR+AC +VH FT  VIQERR  L  QG + +LK K + KTLDFIDVLLL++DEDGKELS
Sbjct: 263 RFRQACDMVHHFTTEVIQERRRALRQQGAEAWLKAK-QGKTLDFIDVLLLARDEDGKELS 321

Query: 315 DEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDD 374
           DEDIRAEADTFMFEGHDTT+SG+SW+L++LAK+PEYQE+CR+E+QE++K RE  E+EWDD
Sbjct: 322 DEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDD 381

Query: 375 LAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW 434
           L QLPF TMCIKESLR +PPV ++SR CT+D  LPDGR+IPKGI+CL++I G H+NPTVW
Sbjct: 382 LTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW 441

Query: 435 PDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPT 494
           PD +VY+P+RFD +N ++RSPLA++PFSAGPRNCIGQ+FAMAE++VV+ALTLL FR+   
Sbjct: 442 PDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVD 501

Query: 495 HT-EPRRKPELILRAEGGLWLRVEPL 519
            T + RRKPELILR E GLWL+VEPL
Sbjct: 502 RTRKVRRKPELILRTENGLWLKVEPL 527


>gi|153218660 cytochrome P450, family 4, subfamily B, polypeptide 1
           isoform b [Homo sapiens]
          Length = 511

 Score =  414 bits (1064), Expect = e-115
 Identities = 222/522 (42%), Positives = 316/522 (60%), Gaps = 20/522 (3%)

Query: 4   LSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGH 63
           LSLS+  LG  A+     L+LV G   L  +L    T     + +  FP PP  +W +GH
Sbjct: 6   LSLSFSSLGLWASG----LILVLGFLKLIHLLLRRQTL---AKAMDKFPGPPT-HWLFGH 57

Query: 64  QGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMI 123
              +  T   +  +      +P    LW G     L +  PD  + + S     AP    
Sbjct: 58  ALEIQETGS-LDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPD--- 113

Query: 124 FYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLAS 183
            Y F   W+G GLL+  G KW +HR++LTP FH+++LKPY+ +F +S  IM DKW+  A 
Sbjct: 114 VYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAR 173

Query: 184 EGSARLDMFEHISLMTLDSLQKCVFSF-ESNCQEKPSEYIAAILELSAFVEKRNQQILLH 242
           EG +  D+F  +  M L++L KC F   ++    + S Y  A+ +L+  +++R      H
Sbjct: 174 EGKS-FDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYH 232

Query: 243 TDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVL 302
            DF+Y+LTP G+RF RAC + HD TD VI+ER+  L  + +   ++N+   + LDF+D+L
Sbjct: 233 NDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNR---RHLDFLDIL 289

Query: 303 LLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELL 362
           L ++DED  +LSD D+RAE DTFMFEGHDTT SG+SW LY +A +PE+Q +CR+EV+E+L
Sbjct: 290 LGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREIL 349

Query: 363 KDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLI 422
            D++    +WDDL ++ +LTMCIKES RL+PPVP + R  ++     DGR +P G +  +
Sbjct: 350 GDQD--FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISM 407

Query: 423 NIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
           +I  +H N  VWPDPEV+D  RF  EN  +R P AF+PFSAGPRNCIGQ FAM+EMKVV 
Sbjct: 408 HIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVT 467

Query: 483 ALTLLHFRI-LPTHTEPRRKPELILRAEGGLWLRVEPLGANS 523
           A+ LL F   L     P + P+L+LR++ G  L ++PLG  S
Sbjct: 468 AMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGS 509


>gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide 1
           isoform a [Homo sapiens]
          Length = 512

 Score =  412 bits (1058), Expect = e-115
 Identities = 222/523 (42%), Positives = 314/523 (60%), Gaps = 21/523 (4%)

Query: 4   LSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGH 63
           LSLS+  LG  A+     L+LV G   L  +L    T     + +  FP PP  +W +GH
Sbjct: 6   LSLSFSSLGLWASG----LILVLGFLKLIHLLLRRQTL---AKAMDKFPGPPT-HWLFGH 57

Query: 64  QGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMI 123
              +  T   +  +      +P    LW G     L +  PD  + + S     AP    
Sbjct: 58  ALEIQETGS-LDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPD--- 113

Query: 124 FYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLAS 183
            Y F   W+G GLL+  G KW +HR++LTP FH+++LKPY+ +F +S  IM DKW+  A 
Sbjct: 114 VYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAR 173

Query: 184 EGSARLDMFEHISLMTLDSLQKCVFSFESNC--QEKPSEYIAAILELSAFVEKRNQQILL 241
           EG +  D+F  +  M L++L KC F          + S Y  A+ +L+  +++R      
Sbjct: 174 EGKS-FDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQY 232

Query: 242 HTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDV 301
           H DF+Y+LTP G+RF RAC + HD TD VI+ER+  L  + +   ++N+   + LDF+D+
Sbjct: 233 HNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNR---RHLDFLDI 289

Query: 302 LLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQEL 361
           LL ++DED  +LSD D+RAE DTFMFEGHDTT SG+SW LY +A +PE+Q +CR+EV+E+
Sbjct: 290 LLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREI 349

Query: 362 LKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCL 421
           L D++    +WDDL ++ +LTMCIKES RL+PPVP + R  ++     DGR +P G +  
Sbjct: 350 LGDQD--FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLIS 407

Query: 422 INIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVV 481
           ++I  +H N  VWPDPEV+D  RF  EN  +R P AF+PFSAGPRNCIGQ FAM+EMKVV
Sbjct: 408 MHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVV 467

Query: 482 LALTLLHFRI-LPTHTEPRRKPELILRAEGGLWLRVEPLGANS 523
            A+ LL F   L     P + P+L+LR++ G  L ++PLG  S
Sbjct: 468 TAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLKPLGPGS 510


>gi|158937242 cytochrome P450, family 4, subfamily A, polypeptide 11
           [Homo sapiens]
          Length = 519

 Score =  411 bits (1056), Expect = e-115
 Identities = 232/508 (45%), Positives = 314/508 (61%), Gaps = 22/508 (4%)

Query: 15  AASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEEGM 74
           AAS  +LLLL+  +  L     W        + LQ FP PP  +W +GH   +   +E +
Sbjct: 21  AASLLILLLLLIKAVQLYLHRQWLL------KALQQFPCPPS-HWLFGHIQELQQDQE-L 72

Query: 75  KTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGD 134
           + + + V T+P     WL      + L  PD ++ I   S    PK    Y FL PW+G 
Sbjct: 73  QRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSD---PKSHGSYRFLAPWIGY 129

Query: 135 GLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEH 194
           GLLL  G  W +HRRMLTPAFH++ILKPY+ +   SV +M DKW+ L  + S  L++F+H
Sbjct: 130 GLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSP-LEVFQH 188

Query: 195 ISLMTLDSLQKCVFSFESNCQ--EKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPD 252
           +SLMTLD++ KC FS + + Q       YI AI +L+  V  R +      D +Y LT  
Sbjct: 189 VSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSA 248

Query: 253 GQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKE 312
           G+   RAC L H  TD VIQ R+  L  +G  + +K K   + LDF+D+LLL+K E+G  
Sbjct: 249 GRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRK---RHLDFLDILLLAKMENGSI 305

Query: 313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEW 372
           LSD+D+RAE DTFMFEGHDTTASG+SW+LY LA HP++QE+CR+E+  LL D     I W
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGD--GASITW 363

Query: 373 DDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPT 432
           + L Q+P+ TMCIKE+LRL+PPVP I R  +     PDGR +PKGI+ L++I G+H+NP 
Sbjct: 364 NHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPK 423

Query: 433 VWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRIL 492
           VWP+PEV+DPFRF   + +     AF+PFS G RNCIG+ FAM E+KV  ALTLL F +L
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSH--AFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELL 481

Query: 493 PTHTE-PRRKPELILRAEGGLWLRVEPL 519
           P  T  P     L+L+++ G+ LR+  L
Sbjct: 482 PDPTRIPIPIARLVLKSKNGIHLRLRRL 509


>gi|29837648 cytochrome P450, family 4, subfamily X, polypeptide 1
           [Homo sapiens]
          Length = 509

 Score =  410 bits (1055), Expect = e-114
 Identities = 205/477 (42%), Positives = 296/477 (62%), Gaps = 14/477 (2%)

Query: 46  RRLQCFPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPD 105
           R L+ FP PP  +WF GHQ  +   ++ M+ L +++  YP+ F  W+GP      +  PD
Sbjct: 41  RDLRPFPAPPT-HWFLGHQKFIQ--DDNMEKLEEIIEKYPRAFPFWIGPFQAFFCIYDPD 97

Query: 106 IIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMK 165
             + + S +    PK      F  P LG GL    G KW +HRR+LTP FHFNILK Y++
Sbjct: 98  YAKTLLSRTD---PKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIE 154

Query: 166 IFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSE--YIA 223
           +   SV +M DKW+++ S     ++++EHI+ M+LD + KC FS E+NCQ   +   Y  
Sbjct: 155 VMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTNSTHDPYAK 214

Query: 224 AILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGI 283
           AI ELS  +  R   +L H+D ++ L+P G RF++   +++ +TD +IQER+ +L     
Sbjct: 215 AIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVK 274

Query: 284 DDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYH 343
            D   N  K K  DF+D++L +KDE G   SD D+ +E  TF+  GHDT A+ +SW+LY 
Sbjct: 275 QD---NTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYC 331

Query: 344 LAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCT 403
           LA +PE+QE+CR+EV+ +L D     I WD L ++ + TMCIKE+ RL P VP ISR  +
Sbjct: 332 LALNPEHQERCREEVRGILGDGS--SITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 389

Query: 404 QDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSA 463
           +    PDG  +P GI  +++I G+H+NP VW +P+V+DP RF QEN  +R P A++PFSA
Sbjct: 390 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 449

Query: 464 GPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKP-ELILRAEGGLWLRVEPL 519
           G RNCIGQ FAM E+KV +AL LLHFR+ P  T P   P   IL+ + G++L ++ L
Sbjct: 450 GSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKL 506


>gi|62952506 cytochrome P450, family 4, subfamily A, polypeptide 22
           [Homo sapiens]
          Length = 519

 Score =  387 bits (993), Expect = e-107
 Identities = 216/477 (45%), Positives = 296/477 (62%), Gaps = 16/477 (3%)

Query: 46  RRLQCFPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPD 105
           + LQ FP PP  +W +GH       +E ++ + + V T+P     W+      + L  PD
Sbjct: 46  KALQQFPCPPS-HWLFGHIQEFQHDQE-LQRIQERVKTFPSACPYWIWGGKVRVQLYDPD 103

Query: 106 IIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMK 165
            ++ I   S    PK    Y FL P +G GLLL  G  W +HRRMLTPAFH +ILKPY+ 
Sbjct: 104 YMKVILGRSD---PKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVG 160

Query: 166 IFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQ--EKPSEYIA 223
           +   SV +M DKW+ L  + S  L++F+H+SLMTLD++ K  FS + + Q       YI 
Sbjct: 161 LMADSVRVMLDKWEELLGQDSP-LEVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQ 219

Query: 224 AILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGI 283
           AI +L++ V    +      D +Y LT  G+   RAC L H  TD VIQ R+  L  +G 
Sbjct: 220 AISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGE 279

Query: 284 DDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYH 343
            + +K K   + LDF+D+LLL+K E+G  LSD+D+RAE DTFMFEGHDTTASG+SW+LY 
Sbjct: 280 LEKIKRK---RHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYA 336

Query: 344 LAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCT 403
           LA HP++QE+CR+E+  LL D     I W+ L Q+P+ TMCIKE+LRL+PPVP I R  +
Sbjct: 337 LATHPKHQERCREEIHGLLGD--GASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELS 394

Query: 404 QDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSA 463
                PDGR +PKGI+ L++I G+H+NP VWP+ EV+DP RF   + +     AF+PFS 
Sbjct: 395 TPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSH--AFLPFSG 452

Query: 464 GPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTE-PRRKPELILRAEGGLWLRVEPL 519
           G RNCIG+ FAM ++KV  ALTLL F +LP  T  P     L+L+++ G+ LR+  L
Sbjct: 453 GSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRRL 509


>gi|30023836 cytochrome P450 4Z1 [Homo sapiens]
          Length = 505

 Score =  381 bits (978), Expect = e-105
 Identities = 204/509 (40%), Positives = 311/509 (61%), Gaps = 18/509 (3%)

Query: 7   SWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGL 66
           SWL    + A P+LLL+L+  S LL +V+          R L  FP PP  +WF+GH+  
Sbjct: 4   SWLQ--ELMAHPFLLLILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPA-HWFYGHKEF 60

Query: 67  VTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYG 126
             P +E  +   +L+  YP    LW+GP      +  PD  + +        PK  + + 
Sbjct: 61  Y-PVKE-FEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQD---PKSAVSHK 115

Query: 127 FLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGS 186
            L+ W+G GL+   G KW +HR+++ P F+ +ILK ++ + ++SV +M +KW+   ++ S
Sbjct: 116 ILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNS 175

Query: 187 ARLDMFEHISLMTLDSLQKCVFSFESNCQEKPS--EYIAAILELSAFVEKRNQQILLHTD 244
            RL++F+H+SLMTLDS+ KC FS + + Q   +   Y+ A+  LS    +R    L H D
Sbjct: 176 -RLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHND 234

Query: 245 FLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLL 304
            ++  +  GQ F +    +H FT+ VIQ+R+ +L     D   ++  + +  DF+D+LL 
Sbjct: 235 LVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLK----DKLKQDTTQKRRWDFLDILLS 290

Query: 305 SKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKD 364
           +K E+ K+ S+ D++AE  TFMF GHDTT+S +SW+LY LAK+PE+Q++CR E++ELL D
Sbjct: 291 AKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGD 350

Query: 365 REPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINI 424
                I W+ L+Q+P+ TMCIKE LRL+ PV  ISR   +    PDGR +P GI   INI
Sbjct: 351 GS--SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINI 408

Query: 425 IGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLAL 484
             +H+NP  W DP+V++P RF +EN ++  P AFIPFSAG RNCIGQ FA+ E KV +AL
Sbjct: 409 WALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468

Query: 485 TLLHFRILPTHTEPRRK-PELILRAEGGL 512
           TLL F++ P H+ P +   +++L+++ G+
Sbjct: 469 TLLRFKLAPDHSRPPQPVRQVVLKSKNGI 497


>gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide 2
           [Homo sapiens]
          Length = 525

 Score =  280 bits (716), Expect = 2e-75
 Identities = 183/538 (34%), Positives = 289/538 (53%), Gaps = 38/538 (7%)

Query: 8   WLGLGPVAASPWLLLLLVG--------GSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNW 59
           WLGL       W  LLL G        G+ L+  +L    ++    ++++  P   +   
Sbjct: 5   WLGL------VWQKLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYP 58

Query: 60  FWGHQGLVTPTEEGMKTLTQLVTTYPQGF------KLWLGPTFPLLILCHPDIIRPITSA 113
             GH  L+ P  +G +   Q++  Y + +      KLW+GP  P++ L + + +  I ++
Sbjct: 59  LVGHALLMKP--DGREFFQQIIE-YTEEYRHMPLLKLWVGPV-PMVALYNAENVEVILTS 114

Query: 114 SAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNI 173
           S  +    M  Y FL+PWLG GLL S G+KW   R+MLTP FHF IL+ ++ I N+  NI
Sbjct: 115 SKQIDKSSM--YKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANI 172

Query: 174 MHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKP-SEYIAAILELSAFV 232
           +  K ++  ++ +   + F +I+L  LD + +         Q    SEY+ A+  +S  +
Sbjct: 173 LVKKLEKHINQEA--FNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230

Query: 233 EKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGI---DDFLKN 289
            +R +   L  D  Y +  +G   +++  ++H FT++VI ER   +        D     
Sbjct: 231 FRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGSA 290

Query: 290 KAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPE 349
            +K+K   F+D+LL   D++G  LS EDIR E DTFMFEGHDTTA+ ++W LY L  +PE
Sbjct: 291 PSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPE 350

Query: 350 YQEQCRQEVQELL-KDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVL 408
            Q++   E+ ++  K   P  +E  DL +L +L   IKE+LRL P VP+ +R  ++D  +
Sbjct: 351 VQKKVDHELDDVFGKSDRPATVE--DLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEV 408

Query: 409 PDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNC 468
              RV+ KG   +I    +H +P  +P+PE + P RF  EN + R P A++PFSAGPRNC
Sbjct: 409 AGYRVL-KGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNC 467

Query: 469 IGQAFAMAEMKVVLALTLLHFRILPT--HTEPRRKPELILRAEGGLWLRVEPLGANSQ 524
           IGQ FA+ E K +L+  L HF I       E   + +LILR   G+W++++   A+ +
Sbjct: 468 IGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRRNADER 525


>gi|239757171 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  248 bits (634), Expect = 7e-66
 Identities = 121/157 (77%), Positives = 136/157 (86%)

Query: 150 MLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF++SVNIMH KW  L  E +A LDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDA 269
           F+S CQEKPSEYIA++LELS+ V KRNQQILLH DFLYYLT DG+ F RAC L HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSK 306
            IQE+R TLP+QG+DDFL+ KAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|239751683 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  248 bits (634), Expect = 7e-66
 Identities = 121/157 (77%), Positives = 136/157 (86%)

Query: 150 MLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF++SVNIMH KW  L  E +A LDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDA 269
           F+S CQEKPSEYIA++LELS+ V KRNQQILLH DFLYYLT DG+ F RAC L HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSK 306
            IQE+R TLP+QG+DDFL+ KAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|239746187 PREDICTED: similar to cytochrome P450, family 4,
           subfamily F, polypeptide 2 [Homo sapiens]
          Length = 190

 Score =  248 bits (634), Expect = 7e-66
 Identities = 121/157 (77%), Positives = 136/157 (86%)

Query: 150 MLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFS 209
           ML PAFHFNILKPYMKIF++SVNIMH KW  L  E +A LDMFEH++LMTLDSLQKCVFS
Sbjct: 1   MLMPAFHFNILKPYMKIFDESVNIMHAKWHLLTLEHNACLDMFEHMNLMTLDSLQKCVFS 60

Query: 210 FESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDA 269
           F+S CQEKPSEYIA++LELS+ V KRNQQILLH DFLYYLT DG+ F RAC L HDF DA
Sbjct: 61  FDSQCQEKPSEYIASVLELSSLVAKRNQQILLHMDFLYYLTHDGRHFHRACRLGHDFADA 120

Query: 270 VIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSK 306
            IQE+R TLP+QG+DDFL+ KAKSKTLDFIDVLL+SK
Sbjct: 121 AIQEKRHTLPSQGVDDFLQAKAKSKTLDFIDVLLISK 157


>gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 2 [Homo sapiens]
          Length = 503

 Score =  155 bits (392), Expect = 9e-38
 Identities = 114/415 (27%), Positives = 201/415 (48%), Gaps = 45/415 (10%)

Query: 97  PLLILCHPDIIRPITSASA-AVAPKDMIF--YGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
           P+L++  PD+I+ +      +V    M     GFLK      L  +  ++W R R +L+P
Sbjct: 80  PMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLK----SALSFAEDEEWKRIRTLLSP 135

Query: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
           AF     K  + I ++  +++  +  R  +E S  +++ +     T+D +   +F    +
Sbjct: 136 AFTSVKFKEMVPIISQCGDMLV-RSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLD 194

Query: 214 CQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQE 273
               P +              +N + LL  DFL         F     L   F   V + 
Sbjct: 195 SLNNPQDPFL-----------KNMKKLLKLDFL-------DPFLLLISLF-PFLTPVFEA 235

Query: 274 RRCTLPTQGIDDFLKN----------KAKSK-TLDFIDVLLLSKD----EDGKELSDEDI 318
               L  + +  FLKN          K K K  +DF   ++ S++    +  K LSD ++
Sbjct: 236 LNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLEL 295

Query: 319 RAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQL 378
            A++   +F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P+   +D L Q+
Sbjct: 296 VAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVT--YDALVQM 353

Query: 379 PFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPE 438
            +L M + E+LRL P V  ++R C +D  + +G  IPKG+  ++ I  +H++P  W +PE
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKYWTEPE 412

Query: 439 VYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILP 493
            + P RF ++N        +IPF AGPRNCIG  FA+  +K+ +   L +F   P
Sbjct: 413 KFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467


>gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7
           [Homo sapiens]
          Length = 503

 Score =  154 bits (390), Expect = 1e-37
 Identities = 118/434 (27%), Positives = 209/434 (48%), Gaps = 35/434 (8%)

Query: 97  PLLILCHPDIIRPITSASA-AVAPKDMIF--YGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
           P+L +  PD+I+ +      +V      F   GF+K    + + ++  ++W R R +L+P
Sbjct: 80  PMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMK----NAISIAEDEEWKRIRSLLSP 135

Query: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
            F    LK  + I  +  +++    +R A  G   + +       ++D +    F    +
Sbjct: 136 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKP-VTLKHVFGAYSMDVITSTSFGVSID 194

Query: 214 CQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQE 273
               P +          FVE  N + LL  + L       + F     ++      V   
Sbjct: 195 SLNNPQD---------PFVE--NTKKLLRFNPLDPFVLSIKVFPFLTPILEALNITVFPR 243

Query: 274 RRCTLPTQGIDDFLKNKAKSKTLDFIDVLLL------SKD-EDGKELSDEDIRAEADTFM 326
           +  +  T+ +    + + K      +D L L      SKD E  K LSD ++ A++  F+
Sbjct: 244 KVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFI 303

Query: 327 FEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIK 386
           F G++TT+S LS+++Y LA HP+ Q++ ++E+  +L ++ P    +D + QL +L M + 
Sbjct: 304 FAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPT--YDTVLQLEYLDMVVN 361

Query: 387 ESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFD 446
           E+LRL P    + R C +D  + +G  IPKG+V +I    +H++P  W +PE + P RF 
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEI-NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFS 420

Query: 447 QENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELIL 506
           ++N     P  + PF +GPRNCIG  FA+  MK+ L   L +F       +P ++ ++ L
Sbjct: 421 KKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSF-----KPCKETQIPL 475

Query: 507 RAE-GGLWLRVEPL 519
           +   GGL L  +P+
Sbjct: 476 KLRFGGLLLTEKPI 489


>gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide 4
           [Homo sapiens]
          Length = 503

 Score =  152 bits (385), Expect = 6e-37
 Identities = 112/417 (26%), Positives = 202/417 (48%), Gaps = 49/417 (11%)

Query: 97  PLLILCHPDIIRPITSASA-AVAPKDMIF--YGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
           P+L +  PD+I+ +      +V      F   GF+K      + ++  ++W R R +L+P
Sbjct: 80  PVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMK----SAISIAEDEEWKRLRSLLSP 135

Query: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
            F    LK  + I  +  +++    +R A  G   + + +     ++D +    F    +
Sbjct: 136 TFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKP-VTLKDVFGAYSMDVITSTSFGVNID 194

Query: 214 CQEKPSEYIAAILELSAFVEKRNQQILLHTDFL--YYLTPDGQRFRRACHLVHDFTDAVI 271
               P +          FVE  N + LL  DFL  ++L+            V  F   ++
Sbjct: 195 SLNNPQD---------PFVE--NTKKLLRFDFLDPFFLSIT----------VFPFLIPIL 233

Query: 272 QERRCTLPTQGIDDFLKNKAK-----------SKTLDFIDVLLLSKD----EDGKELSDE 316
           +     +  + + +FL+   K              +DF+ +++ S++    E  K LSD 
Sbjct: 234 EVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDL 293

Query: 317 DIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLA 376
           ++ A++  F+F G++TT+S LS+++Y LA HP+ Q++ ++E+  +L ++ P    +D + 
Sbjct: 294 ELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPT--YDTVL 351

Query: 377 QLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPD 436
           Q+ +L M + E+LRL P    + R C +D  + +G  IPKG+V +I    +H +P  W +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-NGMFIPKGVVVMIPSYALHRDPKYWTE 410

Query: 437 PEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILP 493
           PE + P RF ++N     P  + PF +GPRNCIG  FA+  MK+ L   L +F   P
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467


>gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 1 [Homo sapiens]
          Length = 504

 Score =  151 bits (381), Expect = 2e-36
 Identities = 114/416 (27%), Positives = 201/416 (48%), Gaps = 46/416 (11%)

Query: 97  PLLILCHPDIIRPITSASA-AVAPKDMIF--YGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
           P+L++  PD+I+ +      +V    M     GFLK      L  +  ++W R R +L+P
Sbjct: 80  PMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLK----SALSFAEDEEWKRIRTLLSP 135

Query: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
           AF     K  + I ++  +++  +  R  +E S  +++ +     T+D +   +F    +
Sbjct: 136 AFTSVKFKEMVPIISQCGDMLV-RSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLD 194

Query: 214 CQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQE 273
               P +              +N + LL  DFL         F     L   F   V + 
Sbjct: 195 SLNNPQDPFL-----------KNMKKLLKLDFL-------DPFLLLISLF-PFLTPVFEA 235

Query: 274 RRCTLPTQGIDDFLKN----------KAKSK-TLDFIDVLLLSKD----EDGKELSDEDI 318
               L  + +  FLKN          K K K  +DF   ++ S++    +  K LSD ++
Sbjct: 236 LNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLEL 295

Query: 319 RAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQL 378
            A++   +F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D L Q+
Sbjct: 296 VAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYDALVQM 353

Query: 379 PFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPE 438
            +L M + E+LRL P V  ++R C +D  + +G  IPKG+  ++ I  +H++P  W +PE
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKYWTEPE 412

Query: 439 VYDP-FRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILP 493
            + P  RF ++N        +IPF AGPRNCIG  FA+  +K+ +   L +F   P
Sbjct: 413 KFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 468


>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
           [Homo sapiens]
          Length = 502

 Score =  144 bits (364), Expect = 2e-34
 Identities = 108/407 (26%), Positives = 193/407 (47%), Gaps = 30/407 (7%)

Query: 97  PLLILCHPDIIRPITSA---SAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
           P+L +  PD+IR +      S     + +   GF+K      + L+  ++W R R +L+P
Sbjct: 80  PVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMK----SAISLAEDEEWKRIRSLLSP 135

Query: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
            F    LK    I  +  +++    +R A +G   + + +     ++D +    F    +
Sbjct: 136 TFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKP-VTLKDIFGAYSMDVITGTSFGVNID 194

Query: 214 CQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQE 273
               P +          FVE   +   L   FL  L      F     +      ++  +
Sbjct: 195 SLNNPQD---------PFVESTKK--FLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPK 243

Query: 274 RRCTLPTQGIDDFLKNKAKSKT---LDFIDVLLLSKD----EDGKELSDEDIRAEADTFM 326
                 ++ ++   K++   K    LDF+ +++ S++    E  K LSD ++ A++  F+
Sbjct: 244 DTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFI 303

Query: 327 FEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIK 386
           F G++TT+S LS+ LY LA HP+ Q++ ++E+  +L ++ P    +D + Q+ +L M + 
Sbjct: 304 FAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAP--PTYDAVVQMEYLDMVVN 361

Query: 387 ESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFD 446
           E+LRL P    + R C +D  + +G  IPKG + +I    +H++P  W +PE + P RF 
Sbjct: 362 ETLRLFPVAIRLERTCKKDVEI-NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFS 420

Query: 447 QENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILP 493
           ++      P  + PF  GPRNCIG  FA+  MK+ L   L +F   P
Sbjct: 421 KKK-DSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466


>gi|5729796 cytochrome P450, family 46 [Homo sapiens]
          Length = 500

 Score =  124 bits (310), Expect = 3e-28
 Identities = 126/500 (25%), Positives = 226/500 (45%), Gaps = 68/500 (13%)

Query: 22  LLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGLVTPTEE-GMKTLTQL 80
           LLL+G + LLA  L  T+      R  +  P PP+ ++  GH       +E G + L  +
Sbjct: 5   LLLLGSAVLLAFGLCCTFVHRARSR-YEHIPGPPRPSFLLGHLPCFWKKDEVGGRVLQDV 63

Query: 81  VTTYPQGFKLWLGPTFPL-------LILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLG 133
              + + +    GP   +       +I+  P+ ++    ++     KD   Y  L+   G
Sbjct: 64  FLDWAKKY----GPVVRVNVFHKTSVIVTSPESVKKFLMSTKY--NKDSKMYRALQTVFG 117

Query: 134 DGLLLSG------GDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSA 187
           + L   G       ++W + RR++  AF  + L   M+ FN+    + +  +  A +G  
Sbjct: 118 ERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKA-DGQT 176

Query: 188 RLDMFEHISLMTLDSLQKCVFSFESN----CQEKPSEYIAAILE--------LSAFVEKR 235
            + M + ++   +D L K  F  E++     Q+  S+ +  +LE        L+ F+  +
Sbjct: 177 PVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGK 236

Query: 236 NQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKT 295
            +Q+    + + +L   G+ +              +Q RR  L           + +   
Sbjct: 237 RKQLREVRESIRFLRQVGRDW--------------VQRRREAL----------KRGEEVP 272

Query: 296 LDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCR 355
            D +  +L  K E+G +  DE +     TF   GH+T+A+ L++ +  L++ PE   + +
Sbjct: 273 ADILTQIL--KAEEGAQ-DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQ 329

Query: 356 QEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIP 415
            EV E++  +  ++ E  DL +L +L+  +KESLRL+PP     R   ++ ++ DG  +P
Sbjct: 330 AEVDEVIGSKRYLDFE--DLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI-DGVRVP 386

Query: 416 KGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAM 475
                L +   +    T + DP  ++P RF     K R    + PFS G R+CIGQ FA 
Sbjct: 387 GNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPR--FTYFPFSLGHRSCIGQQFAQ 444

Query: 476 AEMKVVLA--LTLLHFRILP 493
            E+KVV+A  L  L FR++P
Sbjct: 445 MEVKVVMAKLLQRLEFRLVP 464


>gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 3 [Homo sapiens]
          Length = 420

 Score =  117 bits (294), Expect = 2e-26
 Identities = 95/366 (25%), Positives = 174/366 (47%), Gaps = 45/366 (12%)

Query: 97  PLLILCHPDIIRPITSASA-AVAPKDMIF--YGFLKPWLGDGLLLSGGDKWSRHRRMLTP 153
           P+L++  PD+I+ +      +V    M     GFLK      L  +  ++W R R +L+P
Sbjct: 80  PMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLK----SALSFAEDEEWKRIRTLLSP 135

Query: 154 AFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESN 213
           AF     K  + I ++  +++  +  R  +E S  +++ +     T+D +   +F    +
Sbjct: 136 AFTSVKFKEMVPIISQCGDMLV-RSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLD 194

Query: 214 CQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQE 273
               P +              +N + LL  DFL         F     L   F   V + 
Sbjct: 195 SLNNPQDPFL-----------KNMKKLLKLDFL-------DPFLLLISLF-PFLTPVFEA 235

Query: 274 RRCTLPTQGIDDFLKN----------KAKSK-TLDFIDVLLLSKD----EDGKELSDEDI 318
               L  + +  FLKN          K K K  +DF   ++ S++    +  K LSD ++
Sbjct: 236 LNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLEL 295

Query: 319 RAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQL 378
            A++   +F  +DTT++ L +++Y LA HP+ Q++ ++E+  +L ++ P  + +D L Q+
Sbjct: 296 VAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAP--VTYDALVQM 353

Query: 379 PFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPE 438
            +L M + E+LRL P V  ++R C +D  + +G  IPKG+  ++ I  +H++P  W +PE
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEI-NGVFIPKGLAVMVPIYALHHDPKYWTEPE 412

Query: 439 VYDPFR 444
            + P R
Sbjct: 413 KFCPER 418


>gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1
           isoform 1 precursor [Homo sapiens]
          Length = 514

 Score =  113 bits (283), Expect = 4e-25
 Identities = 111/444 (25%), Positives = 200/444 (45%), Gaps = 57/444 (12%)

Query: 76  TLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWL--- 132
           TL +    Y + F++ LG +F  + L  P ++  +    +A   +  I     KPW    
Sbjct: 85  TLVEYHKKYGKIFRMKLG-SFESVHLGSPCLLEALYRTESAYPQRLEI-----KPWKAYR 138

Query: 133 -----GDGLLLSGGDKWSRHRRMLTPAFHFNILKP--YMKIFNKSVNIMHD---KWQRLA 182
                G GLL+  G+ W R R     AF   ++KP   MK+ NK   ++ D   +   L 
Sbjct: 139 DYRKEGYGLLILEGEDWQRVR----SAFQKKLMKPGEVMKLDNKINEVLADFMGRIDELC 194

Query: 183 SEGSARLDMFEHISLMTLDSL-----QKCVFSFESNCQEKPSEYIAAI-LELSAFVEKRN 236
            E     D++  ++  + +S+     +K     + N  ++   +I AI   +S F     
Sbjct: 195 DERGHVEDLYSELNKWSFESICLVLYEKRFGLLQKNAGDEAVNFIMAIKTMMSTFGRMMV 254

Query: 237 QQILLHTDFLYYLTPDGQRFRRACHLVHDFT-DAVIQERRCTLPTQGIDDFLKNKAKSKT 295
             + LH      +  D           H    D + +  +       ID+ L+  ++  +
Sbjct: 255 TPVELHKSLNTKVWQD-----------HTLAWDTIFKSVKAC-----IDNRLEKYSQQPS 298

Query: 296 LDFI-DVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQC 354
            DF+ D+   ++      LS +++ A          +TTA+ L W+LY+L+++P+ Q++ 
Sbjct: 299 ADFLCDIYHQNR------LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKL 352

Query: 355 RQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVI 414
            +E+Q +L + +    E  DL  +P+L  C+KES+RL P VP  +R   +  VL +   +
Sbjct: 353 LKEIQSVLPENQVPRAE--DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGE-YAL 409

Query: 415 PKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFA 474
           PKG V ++N   +  +   + D   + P R+ QE  ++ +P A +PF  G R CIG+  A
Sbjct: 410 PKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEK-EKINPFAHLPFGVGKRMCIGRRLA 468

Query: 475 MAEMKVVLALTLLHFRILPTHTEP 498
             ++ + L   +  + I  T  EP
Sbjct: 469 ELQLHLALCWIVRKYDIQATDNEP 492


>gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score =  105 bits (263), Expect = 8e-23
 Identities = 61/181 (33%), Positives = 105/181 (58%), Gaps = 4/181 (2%)

Query: 311 KELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEI 370
           + L+ ++I  +A  F+  G++   + LS+  Y LA +P+ QE+  +EV ++ K++  +  
Sbjct: 325 RPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKH-MAP 382

Query: 371 EWDDLAQ-LPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHY 429
           E+  L + LP+L M I E+LR++PP    +R   QD  +  G+ IP G V  + +  +H+
Sbjct: 383 EFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL-GQRIPAGAVLEMAVGALHH 441

Query: 430 NPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489
           +P  WP PE ++P RF  E  ++  P  ++PF AGPR+C+G    + E+K+ L   L  F
Sbjct: 442 DPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKF 501

Query: 490 R 490
           R
Sbjct: 502 R 502


>gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score =  105 bits (263), Expect = 8e-23
 Identities = 61/181 (33%), Positives = 105/181 (58%), Gaps = 4/181 (2%)

Query: 311 KELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEI 370
           + L+ ++I  +A  F+  G++   + LS+  Y LA +P+ QE+  +EV ++ K++  +  
Sbjct: 325 RPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKH-MAP 382

Query: 371 EWDDLAQ-LPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHY 429
           E+  L + LP+L M I E+LR++PP    +R   QD  +  G+ IP G V  + +  +H+
Sbjct: 383 EFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL-GQRIPAGAVLEMAVGALHH 441

Query: 430 NPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489
           +P  WP PE ++P RF  E  ++  P  ++PF AGPR+C+G    + E+K+ L   L  F
Sbjct: 442 DPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKF 501

Query: 490 R 490
           R
Sbjct: 502 R 502


>gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide 1
           [Homo sapiens]
          Length = 501

 Score =  102 bits (253), Expect = 1e-21
 Identities = 83/320 (25%), Positives = 142/320 (44%), Gaps = 35/320 (10%)

Query: 208 FSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYY-LTPDG---QRFRRACHLV 263
           F++E    +   E  +  +EL+A     +  + L+  F +  + P G   Q FR A  +V
Sbjct: 200 FTYEDTDFQHMIELFSENVELAA-----SASVFLYNAFPWIGILPFGKHQQLFRNAA-VV 253

Query: 264 HDFTDAVIQE----RRCTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIR 319
           +DF   +I++    R+  LP   +D +L            D +   K++     S E++ 
Sbjct: 254 YDFLSRLIEKASVNRKPQLPQHFVDAYL------------DEMDQGKNDPSSTFSKENLI 301

Query: 320 AEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLP 379
                 +  G +TT + L W +  +A +P  Q Q ++E+  ++      +  WDD  ++P
Sbjct: 302 FSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNG--KPSWDDKCKMP 359

Query: 380 FLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEV 439
           +    + E LR    VP+     T +  +  G  IPKG   + N+  +H++   W DPEV
Sbjct: 360 YTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEV 419

Query: 440 YDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRI-LPTHTEP 498
           + P RF   +       A +PFS G R+C+G+  A  EM +     L  F +  P    P
Sbjct: 420 FHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVP 479

Query: 499 RRKPELILRAEGGLWLRVEP 518
             KP L      G+ L+ +P
Sbjct: 480 DLKPRL------GMTLQPQP 493


>gi|190570174 cytochrome P450, family 21, subfamily A, polypeptide 2
           isoform b [Homo sapiens]
          Length = 465

 Score =  100 bits (250), Expect = 2e-21
 Identities = 102/415 (24%), Positives = 170/415 (40%), Gaps = 32/415 (7%)

Query: 87  GFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSR 146
           GF   L P  P+ +L       PI      +  K ++   +    LGD  LL     W  
Sbjct: 36  GFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDK-LVSRNYPDLSLGDYSLL-----WKA 89

Query: 147 HRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKC 206
           H+++   A    I      +  +   +  +  +R+ ++    + + E  SL+T   +   
Sbjct: 90  HKKLTRSALLLGIRDSMEPVVEQ---LTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYL 146

Query: 207 VFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFL-YYLTPDGQRFRRACHLVHD 265
            F  +         Y   I E+       + QI+    FL ++  P  +R ++A      
Sbjct: 147 TFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAI----- 201

Query: 266 FTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFIDVLLL-----SKDEDGKELSDEDIRA 320
                  E+R  +    +    ++    +  D +D +L      S +E   +L +  +  
Sbjct: 202 -------EKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHM 254

Query: 321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEV-QELLKDREPIEIEWDDLAQLP 379
            A   +  G +TTA+ LSW +  L  HPE Q++ ++E+  EL        + + D A+LP
Sbjct: 255 AAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLP 314

Query: 380 FLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEV 439
            L   I E LRL P VP+     T       G  IP+G V + N+ G H + TVW  P  
Sbjct: 315 LLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHE 374

Query: 440 YDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPT 494
           + P RF +     R+    + F  G R C+G+  A  E+ VVL   L  F +LP+
Sbjct: 375 FWPDRFLEPGKNSRA----LAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPS 425


>gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide 1
           [Homo sapiens]
          Length = 544

 Score =  100 bits (250), Expect = 2e-21
 Identities = 87/293 (29%), Positives = 135/293 (46%), Gaps = 30/293 (10%)

Query: 236 NQQILLHT--DFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKS 293
           N Q+LL     +LYYL P G  F+    +  D T  +          + I D  ++  + 
Sbjct: 264 NSQVLLVNICPWLYYL-PFGP-FKELRQIEKDITSFL---------KKIIKDHQESLDRE 312

Query: 294 KTLDFIDVLLLSKDEDGKELSDEDIRAE------ADTFMFEGHDTTASGLSWVLYHLAKH 347
              DFID+ LL  +E+ K  S+     E       D F+  G DTT + L W L +++ +
Sbjct: 313 NPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFI-AGTDTTTNSLLWCLLYMSLN 371

Query: 348 PEYQEQCRQEVQELL-KDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDF 406
           P+ QE+  +E++ ++  +R P      D AQ+P+    I E  RL   VP+     T + 
Sbjct: 372 PDVQEKVHEEIERVIGANRAP---SLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSEN 428

Query: 407 VLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPR 466
            +  G  IPKG + L N+  +H +P +W  PE + P RF  +  +      FIPF  G R
Sbjct: 429 TVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKR 488

Query: 467 NCIGQAFAMAEMKVVLALTLLHFRI-LPTHTEPRRKPELILRAEGGLWLRVEP 518
            C+G+  A  E+ ++    +  F   LP   E  +KP  +L    GL L   P
Sbjct: 489 VCMGEQLAKMELFLMFVSLMQSFAFALP---EDSKKP--LLTGRFGLTLAPHP 536


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,354,253
Number of Sequences: 37866
Number of extensions: 1059285
Number of successful extensions: 3134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 2874
Number of HSP's gapped (non-prelim): 123
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.