Guide to the Human Genome
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Search of human proteins with 189571657

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189571657 glycerophosphodiester phosphodiesterase domain
containing 5 [Homo sapiens]
         (605 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189571657 glycerophosphodiester phosphodiesterase domain cont...  1241   0.0  
gi|21361649 osteoblast differentiation promoting factor protein ...   437   e-122
gi|33457301 glycerophosphodiester phosphodiesterase domain conta...   361   e-100
gi|7706617 glycerophosphodiester phosphodiesterase 1 [Homo sapiens]    54   3e-07
gi|25901062 hypothetical protein LOC56261 [Homo sapiens]               33   0.58 
gi|113722116 plexin A2 [Homo sapiens]                                  33   0.76 
gi|32698962 glycerophosphodiester phosphodiesterase domain conta...    32   1.7  
gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens]              32   1.7  
gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]         31   2.9  
gi|153791572 olfactory receptor, family 13, subfamily A, member ...    31   3.8  
gi|190358512 transmembrane protein 184C [Homo sapiens]                 30   6.4  
gi|46048143 olfactory receptor, family 1, subfamily N, member 1 ...    30   8.4  
gi|8923394 transmembrane protein 161A [Homo sapiens]                   30   8.4  

>gi|189571657 glycerophosphodiester phosphodiesterase domain
           containing 5 [Homo sapiens]
          Length = 605

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 605/605 (100%), Positives = 605/605 (100%)

Query: 1   MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLTFTFGLTLTWLY 60
           MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLTFTFGLTLTWLY
Sbjct: 1   MVRHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLTFTFGLTLTWLY 60

Query: 61  FWWEVHNDYDEFNWYLYNRMGYWSDWPVPILVTTAAAFAYIAGLLVLALCHIAVGQQMNL 120
           FWWEVHNDYDEFNWYLYNRMGYWSDWPVPILVTTAAAFAYIAGLLVLALCHIAVGQQMNL
Sbjct: 61  FWWEVHNDYDEFNWYLYNRMGYWSDWPVPILVTTAAAFAYIAGLLVLALCHIAVGQQMNL 120

Query: 121 HWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVA 180
           HWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVA
Sbjct: 121 HWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVA 180

Query: 181 GQFARAERTSSQVTILCTFFTVVFALYLAPLTISSPCIMEKKDLGPKPALIGHRGAPMLA 240
           GQFARAERTSSQVTILCTFFTVVFALYLAPLTISSPCIMEKKDLGPKPALIGHRGAPMLA
Sbjct: 181 GQFARAERTSSQVTILCTFFTVVFALYLAPLTISSPCIMEKKDLGPKPALIGHRGAPMLA 240

Query: 241 PEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPASML 300
           PEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPASML
Sbjct: 241 PEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPASML 300

Query: 301 NWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLR 360
           NWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLR
Sbjct: 301 NWTTLQRLNAGQWFLKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKGNATLLLNLR 360

Query: 361 DPPREHPYRSSFINVTLEAVLHSGFPQHQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVAS 420
           DPPREHPYRSSFINVTLEAVLHSGFPQHQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVAS
Sbjct: 361 DPPREHPYRSSFINVTLEAVLHSGFPQHQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVAS 420

Query: 421 LRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHA 480
           LRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHA
Sbjct: 421 LRRGHIQRLNLRYTQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHA 480

Query: 481 LSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVR 540
           LSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVR
Sbjct: 481 LSQVPSPLWIMPPDEYCLMWVTADLVSFTLIVGIFVLQKWRLGGIRSYNPEQIMLSAAVR 540

Query: 541 RTSRDVSIMKEKLIFSEISDGVEVSDVLSVCSDNSYDTYANSTATPVGPRGGGSHTKTLI 600
           RTSRDVSIMKEKLIFSEISDGVEVSDVLSVCSDNSYDTYANSTATPVGPRGGGSHTKTLI
Sbjct: 541 RTSRDVSIMKEKLIFSEISDGVEVSDVLSVCSDNSYDTYANSTATPVGPRGGGSHTKTLI 600

Query: 601 ERSGR 605
           ERSGR
Sbjct: 601 ERSGR 605


>gi|21361649 osteoblast differentiation promoting factor protein
           [Homo sapiens]
          Length = 539

 Score =  437 bits (1123), Expect = e-122
 Identities = 225/506 (44%), Positives = 308/506 (60%), Gaps = 7/506 (1%)

Query: 15  CLSCLTGIYGCRWKRYQRSHDDTTPWERLWFLLLTFTFGLTLTWLYFWWEVHNDYDEFNW 74
           CL CL   Y C W++  R    T+  + +WF LL  TF L+L+WLY    + ND   FN 
Sbjct: 14  CLHCL---YSCHWRKCPRERMQTSKCDCIWFGLLFLTFLLSLSWLYIGLVLLNDLHNFNE 70

Query: 75  YLYNRMGYWSDWPVPILVTTAAAFAYIAGLLVLALCHIAVGQQMNLHWLHKIGLVVILAS 134
           +L+ R G+W DW +  L+  +    Y + LLVLAL      Q ++LH LHK+ L++I+  
Sbjct: 71  FLFRRWGHWMDWSLAFLLVISLLVTYASLLLVLALLLRLCRQPLHLHSLHKVLLLLIMLL 130

Query: 135 TVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWIVAGQFARAERTSSQVT 194
               +  +   W+ EW  L +SLQ TAPFLH+GA A + +L+W VA  F R  R   ++ 
Sbjct: 131 VAAGLVGLDIQWQQEWHSLRVSLQATAPFLHIGAAAGIALLAWPVADTFYRIHRRGPKIL 190

Query: 195 ILCTFFTVVFALYLAPLTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQ 254
           +L  FF VV  +YLAPL ISSPCIME +DL PKP L+GHRGAPMLAPE+TLMS RK  E 
Sbjct: 191 LLLLFFGVVLVIYLAPLCISSPCIMEPRDLPPKPGLVGHRGAPMLAPENTLMSLRKTAEC 250

Query: 255 KLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFPELARRPASMLNWTTLQRLNAGQWF 314
                + D+ +S DGVPFLMHD  L RTTNV   FP      +S  +WT L+RLNAG WF
Sbjct: 251 GATVFETDVMVSSDGVPFLMHDEHLSRTTNVASVFPTRITAHSSDFSWTELKRLNAGSWF 310

Query: 315 LKTDPFWTASSLSPSDHREAQNQSICSLAELLELAKG-NATLLLNLRDPPREHPYRSSFI 373
           L+  PFW A  L+  D +EA++Q++ +L ELLE A   N +++ +LR PP+ H Y  +F+
Sbjct: 311 LERRPFWGAKPLAGPDQKEAESQTVPALEELLEEAAALNLSIMFDLRRPPQNHTYYDTFV 370

Query: 374 NVTLEAVLHSGFPQHQVMWLPSRQRPLVRKVAPGFQQTSGSKEAVASLRRGHIQRLNLRY 433
             TLE VL++  PQ  V WLP   R  V++ APG +Q  G +      R    Q LNL Y
Sbjct: 371 IQTLETVLNARVPQAMVFWLPDEDRANVQRRAPGMRQIYGRQ---GGNRTERPQFLNLPY 427

Query: 434 TQVSRQELRDYASWNLSVNLYTVNAPWLFSLLWCAGVPSVTSDNSHALSQVPSPLWIMPP 493
             +   +++     N+SVNL+ VN PWLFSLLWCAGV SVT+++   L Q+  P+W++ P
Sbjct: 428 QDLPLLDIKALHKDNVSVNLFVVNKPWLFSLLWCAGVDSVTTNDCQLLQQMRYPIWLITP 487

Query: 494 DEYCLMWVTADLVSFTLIVGIFVLQK 519
             Y ++WV  + VS  L++  F+LQ+
Sbjct: 488 QTYLIIWVITNCVSTMLLLWTFLLQR 513


>gi|33457301 glycerophosphodiester phosphodiesterase domain
           containing 4 [Homo sapiens]
          Length = 520

 Score =  361 bits (927), Expect = e-100
 Identities = 199/522 (38%), Positives = 291/522 (55%), Gaps = 35/522 (6%)

Query: 59  LYFWWEVHNDYDEFNWYLYNRMGYWSDWPVPILVTTAAAFAYIAGLLVLALCHIAVGQQM 118
           L+ W E  ++Y  F+W  +   GYW  W + IL       AY + LL+L    +    ++
Sbjct: 3   LFLWIETSSEYFNFDWVTFLGTGYWFFWSIFILSLARILTAYSSLLLLLGFLLLWERIEL 62

Query: 119 NLHWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTMLSWI 178
            LH  HKI +++++   V+ M  + + W++ W V  +S+Q  AP++H+ ++  + +L W 
Sbjct: 63  YLHLCHKILILLVILLCVILMFIICKFWKERWLVAGLSMQIFAPYVHLVSITVMVILFWP 122

Query: 179 VAGQFARAER--------------------------TSSQVTILCTFFTVVFALYLAPLT 212
           VA   A  ER                             QV +   F  ++  LYL PL 
Sbjct: 123 VAFYVACLEREVRMRRYRMTHSEKKRLKQCNVITRLRGLQVPVGLPFLLILLGLYLMPLG 182

Query: 213 ISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPF 272
           I SPCI EK++LGPKP + GHRGAPML PE+T+MSF KA+E   +GL+ DI +S D VPF
Sbjct: 183 IYSPCIQEKENLGPKPTIFGHRGAPMLGPENTMMSFEKAVEHGAHGLETDIHLSYDHVPF 242

Query: 273 LMHDTTLRRTTNVEEEFPELARRPASMLNWTTLQRLNAGQWFLKTD--PFWTASSLSPSD 330
           LMHD  L+RTTN+ E  PE A    +  NW  L  LNAG+WF+K +  PF+    LS +D
Sbjct: 243 LMHDFDLKRTTNIGEVQPESACENPAFFNWDFLSTLNAGKWFVKPELRPFYNMKPLSEAD 302

Query: 331 HREAQNQSICSLAELLELA-KGNATLLLNLRDPPREHPYRSSFINVTLEAVLHSGFPQHQ 389
              A+NQSI +LA+LL LA K    ++ +L  PP +HP R +F+   +  +L S   QH 
Sbjct: 303 KERARNQSIPTLADLLTLAEKERKFVIFDLHRPPPKHPLRHTFVRQVVSVILASKIEQHL 362

Query: 390 VMWLPSRQRPLVRKVAPGFQQTSGSKEAVASLRRGHIQRLNLRYTQVSRQELRDYASWNL 449
           + WLP+  R  VR VAPGFQ   G   ++ +L + +I  +N+ Y ++    LRDY + N+
Sbjct: 363 IFWLPAHDRQYVRSVAPGFQHV-GRLVSIETLAKNNISIINVDYKKLFPNGLRDYKAANI 421

Query: 450 SVNLYTVNAPWLFSLLWCAGVPSVTSDNSHALSQVPSPLWIMPPDEYCLMWVTADLVSFT 509
            +N+YTVN PWLFSL WC+ + SVT+DN   LSQ+  P + M P  Y  MW+ AD++S  
Sbjct: 422 HINVYTVNEPWLFSLAWCSRINSVTTDNIGLLSQLDHPHFFMTPKFYVFMWLLADIISVL 481

Query: 510 LIVGIFVLQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKE 551
            IV IF    WR    R    E++  +++ R  ++  S  +E
Sbjct: 482 FIVAIFCFH-WR----RETEKEKLFETSSTRTDTQSGSKNEE 518


>gi|7706617 glycerophosphodiester phosphodiesterase 1 [Homo sapiens]
          Length = 331

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 30/78 (38%), Positives = 41/78 (52%)

Query: 231 IGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFP 290
           I HRG    APE+TL + R+A +    G++ DI  + DG+P LMHD T+ RTT+      
Sbjct: 68  IAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTTDGTGRLC 127

Query: 291 ELARRPASMLNWTTLQRL 308
           +L       LN     RL
Sbjct: 128 DLTFEQIRKLNPAANHRL 145


>gi|25901062 hypothetical protein LOC56261 [Homo sapiens]
          Length = 672

 Score = 33.5 bits (75), Expect = 0.58
 Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 10/91 (10%)

Query: 228 PALIGHRGA------PMLAP--EHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTT- 278
           P  +GHRGA        LA   E+T+ S R A       ++ D+ +S D VP + HD T 
Sbjct: 318 PLDVGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTC 377

Query: 279 -LRRTTNVEEEFPELARRPASMLNWTTLQRL 308
            L      + +  EL   P   L +  LQ L
Sbjct: 378 CLTMKKKFDADPVELFEIPVKELTFDQLQLL 408


>gi|113722116 plexin A2 [Homo sapiens]
          Length = 1894

 Score = 33.1 bits (74), Expect = 0.76
 Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 2/28 (7%)

Query: 13  QLCLSCLTGIYGCRWKRYQR--SHDDTT 38
           QLCLSC+   + C W +Y+   +HD TT
Sbjct: 660 QLCLSCVNSAFRCHWCKYRNLCTHDPTT 687


>gi|32698962 glycerophosphodiester phosphodiesterase domain
           containing 1 [Homo sapiens]
          Length = 314

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 19/62 (30%), Positives = 30/62 (48%)

Query: 231 IGHRGAPMLAPEHTLMSFRKALEQKLYGLQADITISLDGVPFLMHDTTLRRTTNVEEEFP 290
           I HRG      E+T+ +F+ A++     L+ D  I+ D    + HD  L+R T V     
Sbjct: 43  ISHRGGAGENLENTMAAFQHAVKIGTDTLELDCHITKDEQVVVSHDENLKRATGVNVNIS 102

Query: 291 EL 292
           +L
Sbjct: 103 DL 104


>gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens]
          Length = 882

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 27/128 (21%), Positives = 54/128 (42%), Gaps = 11/128 (8%)

Query: 155 ISLQGTAPFLHV--GAVAAVTMLSWIVAGQFARAERTSSQVTILCTFF--TVVFALYLAP 210
           ++++   P++ V  G V   T  SW++A + A       + + LC+++  +       A 
Sbjct: 1   MAVRSRRPWMSVALGLVLGFTAASWLIAPRVAELSERKRRGSSLCSYYGRSAAGPRAGAQ 60

Query: 211 LTISSPCIMEKKDLGPKPALIGHRGAPMLAPEHTLMSFRKA-------LEQKLYGLQADI 263
             +  P    +++  P PA    +G P+      + SFR +       L+Q+  G + + 
Sbjct: 61  QPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRRGREPEG 120

Query: 264 TISLDGVP 271
              L G P
Sbjct: 121 ATGLPGAP 128


>gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens]
          Length = 383

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 19/99 (19%)

Query: 5   QPLQYYEPQLCLSC-LTGIYGCRWKRYQRSHDDTTPWERLWFLLLTFTFGLTLT------ 57
           QPLQ     L   C LT     RW R +R+ +  +  ++       F F L +T      
Sbjct: 93  QPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAF 152

Query: 58  -----WLYFWWEVHNDY-------DEFNWYLYNRMGYWS 84
                WLY  WEV N Y        ++ +Y+     YWS
Sbjct: 153 LYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEMSFYWS 191


>gi|153791572 olfactory receptor, family 13, subfamily A, member 1
           [Homo sapiens]
          Length = 328

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 18/98 (18%), Positives = 48/98 (48%), Gaps = 3/98 (3%)

Query: 115 GQQMNLHWLHKIGLVVILASTVVAMSAVAQLWEDEWEVLLISLQGTAPFLHVGAVAAVTM 174
           G  + +H+  ++  +++L+ +   ++ V  +  D +  ++  L   A +  + +      
Sbjct: 188 GPNVIIHFFCEVPPLLLLSCSSTYVNGVMIVLADAFYGIVNFLMTIASYGFIVSSILKVK 247

Query: 175 LSWIVAGQFARAERTSSQVTILCTFFTVVFALYLAPLT 212
            +W   G+       SS +T++C ++T VF  Y++P++
Sbjct: 248 TAW---GRQKAFSTCSSHLTVVCMYYTAVFYAYISPVS 282


>gi|190358512 transmembrane protein 184C [Homo sapiens]
          Length = 438

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 6/82 (7%)

Query: 517 LQKWRLGGIRSYNPEQIMLSAAVRRTSRDVSIMKEKLIFSEISDGVEVSDVLSVCSDNSY 576
           L  W +  IR    EQ      VR   R V     K +F E  D  E + +LS  S ++ 
Sbjct: 331 LAMWDVSDIRDDISEQ------VRHVGRTVRGHPRKKLFPEDQDQNEHTSLLSSSSQDAI 384

Query: 577 DTYANSTATPVGPRGGGSHTKT 598
              ++   +P+G   G  HT T
Sbjct: 385 SIASSMPPSPMGHYQGFGHTVT 406


>gi|46048143 olfactory receptor, family 1, subfamily N, member 1
           [Homo sapiens]
          Length = 311

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 15/83 (18%)

Query: 151 EVLLISLQGTA---PFL-----HVGAVAAVTMLSWIVAGQFARAERT-SSQVTILCTFFT 201
           E+++  L GT    PFL     ++  V A+  +     G   +A  T SS + ++C F+ 
Sbjct: 194 EMMVFVLGGTVLIVPFLCIVTSYIHIVPAILRVR--TRGGVGKAFSTCSSHLCVVCVFYG 251

Query: 202 VVFALYLAPLTISSPCIMEKKDL 224
            +F+ YL P +I+S    E+KD+
Sbjct: 252 TLFSAYLCPPSIAS----EEKDI 270


>gi|8923394 transmembrane protein 161A [Homo sapiens]
          Length = 479

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 180 AGQFARAERTSSQVTILCTFFTVVFALYLAPLTISSPCIMEKKDLGPKPALIGHRGAPML 239
           AG+    E     V + C + TVV   YL PL ++  C +  K LG     +G   AP+L
Sbjct: 352 AGRIEAREIQQRVVRVYC-YVTVVSLQYLTPLILTLNCTLLLKTLGGYSWGLG--PAPLL 408

Query: 240 APE 242
           +P+
Sbjct: 409 SPD 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,683,450
Number of Sequences: 37866
Number of extensions: 1044579
Number of successful extensions: 2388
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2377
Number of HSP's gapped (non-prelim): 14
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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