Guide to the Human Genome
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Search of human proteins with 189458889

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189458889 RWD domain containing 3 isoform b [Homo sapiens]
         (195 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189458889 RWD domain containing 3 isoform b [Homo sapiens]         394   e-110
gi|153252154 RWD domain containing 3 isoform a [Homo sapiens]         386   e-108
gi|8393018 RWD domain containing 2B [Homo sapiens]                     40   0.001
gi|34222104 hypothetical protein LOC26074 [Homo sapiens]               32   0.26 
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]     30   1.7  
gi|34878787 ring finger protein 25 [Homo sapiens]                      29   2.2  
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         28   3.8  
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         28   3.8  
gi|65287717 eukaryotic translation initiation factor 2 alpha kin...    28   3.8  
gi|239750922 PREDICTED: hypothetical protein [Homo sapiens]            28   4.9  
gi|239745320 PREDICTED: hypothetical protein XP_002343437 [Homo ...    28   4.9  
gi|208431781 cyclic nucleotide gated channel beta 1 isoform b [H...    27   8.4  
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    27   8.4  
gi|170763479 MMS19 nucleotide excision repair homolog [Homo sapi...    27   8.4  

>gi|189458889 RWD domain containing 3 isoform b [Homo sapiens]
          Length = 195

 Score =  394 bits (1011), Expect = e-110
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 60
           MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN
Sbjct: 1   MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 60

Query: 61  YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 120
           YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET
Sbjct: 61  YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 120

Query: 121 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL 180
           GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL
Sbjct: 121 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL 180

Query: 181 ILLQGDRNNLKVPKS 195
           ILLQGDRNNLKVPKS
Sbjct: 181 ILLQGDRNNLKVPKS 195


>gi|153252154 RWD domain containing 3 isoform a [Homo sapiens]
          Length = 267

 Score =  386 bits (991), Expect = e-108
 Identities = 191/191 (100%), Positives = 191/191 (100%)

Query: 1   MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 60
           MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN
Sbjct: 1   MAEPVQEELSVLAAIFCRPHEWEVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVN 60

Query: 61  YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 120
           YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET
Sbjct: 61  YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 120

Query: 121 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL 180
           GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL
Sbjct: 121 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFMGKIIL 180

Query: 181 ILLQGDRNNLK 191
           ILLQGDRNNLK
Sbjct: 181 ILLQGDRNNLK 191


>gi|8393018 RWD domain containing 2B [Homo sapiens]
          Length = 319

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 6/133 (4%)

Query: 57  LPVNYPSCLPGISINSEQLTRAQCVTVKENLLEQAES-LLSEPMVHELVLWIQQNLRHIL 115
           LP  YP+ LP I++ S  L+R+Q   +  +L    +     +  +     W++++    +
Sbjct: 107 LPFKYPAVLPEITVRSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYV 166

Query: 116 SQPETGSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFM 175
           S+  + S +   T  +   +   LWI   +  H+  K K   I+E WA +L L+G  M  
Sbjct: 167 SRDTSSSPTTGSTVQSVDLIFTRLWI---YSHHIYNKCKRKNILE-WAKELSLSGFSM-P 221

Query: 176 GKIILILLQGDRN 188
           GK  ++ ++G ++
Sbjct: 222 GKPGVVCVEGPQS 234


>gi|34222104 hypothetical protein LOC26074 [Homo sapiens]
          Length = 1237

 Score = 32.3 bits (72), Expect = 0.26
 Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 23   EVLSRSETDGTVFRIHTKAEGFMDADIPLELVFHLPVNYPSCLPGISINSEQLTRAQCVT 82
            E+++ S  +GT FRIH      ++    L        NY           EQL    C  
Sbjct: 1075 ELVTGSAKNGTYFRIHINKYKMVETITCLSREPFPASNYIRLFG----QHEQLLNNLCAR 1130

Query: 83   VKENLLEQAESLLSEP----MVHELVLWIQQNLRHILSQPE 119
              ENL+    S  +EP    + H+  + +++ LR IL+  E
Sbjct: 1131 YDENLITDLYSYFTEPWCLALFHDRFIDLRKELRQILASKE 1171


>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
          Length = 869

 Score = 29.6 bits (65), Expect = 1.7
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 11/94 (11%)

Query: 61  YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHILSQPET 120
           +  C PG+      + R  C+ VKE L    E L+ E   H     + ++  H+LS PE 
Sbjct: 379 FQECSPGVVPTPIPICREYCLAVKE-LFCAKEWLVMEEKTHR---GLYRSEMHLLSVPE- 433

Query: 121 GSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTK 154
                 C+   S   D      L HLD+ +   K
Sbjct: 434 ------CSKLPSMHWDPTACARLPHLDYNKENLK 461


>gi|34878787 ring finger protein 25 [Homo sapiens]
          Length = 459

 Score = 29.3 bits (64), Expect = 2.2
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 53  LVFHLPVNYPSCLPGISI-NSEQLTRAQCVTVKENLLEQAESLLSEPMVHELV 104
           LV  +P  YP  +P ISI N   L+  Q  T+ + L   A++ L   M++EL+
Sbjct: 66  LVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELI 118


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 28.5 bits (62), Expect = 3.8
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%)

Query: 77   RAQCVTVKENLLEQ--AESLLSEPMVHELVLWIQQNLRHILSQPE--TG-SGSEKCTFST 131
            + QCV  K  +L Q  +E L  E    E  +W+Q+N+  I+ Q +  TG  G E    S 
Sbjct: 3518 KLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSP 3577

Query: 132  STT 134
            ST+
Sbjct: 3578 STS 3580


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 28.5 bits (62), Expect = 3.8
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 5/63 (7%)

Query: 77   RAQCVTVKENLLEQ--AESLLSEPMVHELVLWIQQNLRHILSQPE--TG-SGSEKCTFST 131
            + QCV  K  +L Q  +E L  E    E  +W+Q+N+  I+ Q +  TG  G E    S 
Sbjct: 3510 KLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGEEPSLVSP 3569

Query: 132  STT 134
            ST+
Sbjct: 3570 STS 3572


>gi|65287717 eukaryotic translation initiation factor 2 alpha kinase
           4 [Homo sapiens]
          Length = 1649

 Score = 28.5 bits (62), Expect = 3.8
 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 1/64 (1%)

Query: 49  IPLELVFHLPVNYPSCLPGISI-NSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWI 107
           + ++L    P  YP  +P I + N++ L+      +K  L E A+    E M+ EL   +
Sbjct: 71  VKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHV 130

Query: 108 QQNL 111
           Q  L
Sbjct: 131 QSFL 134


>gi|239750922 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 923

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 61  YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHI 114
           + + L GI  N +Q+  +Q      +L   A+     P  H L+ W+QQ L+H+
Sbjct: 734 FDTFLEGIKHNLQQVAGSQ----GHSLAFHAQDGDYSPSSHALLFWVQQYLKHL 783


>gi|239745320 PREDICTED: hypothetical protein XP_002343437 [Homo
           sapiens]
          Length = 923

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 61  YPSCLPGISINSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLRHI 114
           + + L GI  N +Q+  +Q      +L   A+     P  H L+ W+QQ L+H+
Sbjct: 734 FDTFLEGIKHNLQQVAGSQ----GHSLAFHAQDGDYSPSSHALLFWVQQYLKHL 783


>gi|208431781 cyclic nucleotide gated channel beta 1 isoform b [Homo
           sapiens]
          Length = 299

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 10/20 (50%), Positives = 14/20 (70%)

Query: 103 LVLWIQQNLRHILSQPETGS 122
           L+LW++QNL  +L QP   S
Sbjct: 158 LLLWLEQNLERVLPQPPKSS 177


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 10/20 (50%), Positives = 14/20 (70%)

Query: 103 LVLWIQQNLRHILSQPETGS 122
           L+LW++QNL  +L QP   S
Sbjct: 158 LLLWLEQNLERVLPQPPKSS 177


>gi|170763479 MMS19 nucleotide excision repair homolog [Homo
           sapiens]
          Length = 1030

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 3/75 (4%)

Query: 71  NSEQLTRAQCVTVKENLLEQAESLLSEPMVHELVLWIQQNLR-HILSQPETGSGSEKCTF 129
           N E  TRA+ + +   +L    +LL E  V  L+L+ +  L+ H L  P    G +    
Sbjct: 59  NPEPRTRARAIQLLSQVLLHCHTLLLEKEVVHLILFYENRLKDHHLVIPSVLQGLK--AL 116

Query: 130 STSTTMDDGLWITLL 144
           S    +  GL +++L
Sbjct: 117 SLCVALPPGLAVSVL 131


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,317,049
Number of Sequences: 37866
Number of extensions: 286755
Number of successful extensions: 650
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 645
Number of HSP's gapped (non-prelim): 14
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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