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Search of human proteins with 189181666
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189181666 hexosaminidase A preproprotein [Homo sapiens]
(529 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189181666 hexosaminidase A preproprotein [Homo sapiens] 1104 0.0
gi|4504373 hexosaminidase B preproprotein [Homo sapiens] 610 e-174
gi|239742065 PREDICTED: hypothetical protein XP_002342402 [Homo ... 35 0.22
gi|239752588 PREDICTED: hypothetical protein XP_002348309, parti... 33 0.64
gi|239752515 PREDICTED: similar to double homeobox, 4 [Homo sapi... 33 0.84
gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo sapi... 32 1.4
gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo sapi... 32 1.4
gi|239744246 PREDICTED: hypothetical protein XP_002343082 [Homo ... 32 1.4
gi|239744244 PREDICTED: similar to double homeobox, 4 [Homo sapi... 32 1.4
gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo sapi... 32 1.4
gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo sapi... 32 1.4
gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens] 32 1.4
gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens] 32 1.4
gi|194272172 double homeobox, 4 [Homo sapiens] 32 1.4
gi|194272217 double homeobox, 4-like [Homo sapiens] 32 1.4
gi|194272216 double homeobox, 4-like [Homo sapiens] 32 1.4
gi|194272215 double homeobox, 4-like [Homo sapiens] 32 1.4
gi|194272192 double homeobox, 4-like [Homo sapiens] 32 1.4
gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso... 31 3.2
gi|239758086 PREDICTED: similar to double homeobox, 4 [Homo sapi... 30 4.2
gi|197100900 iroquois homeobox 2 [Homo sapiens] 30 5.5
gi|39930475 iroquois homeobox 2 [Homo sapiens] 30 5.5
gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens] 30 5.5
gi|239743654 PREDICTED: similar to block of proliferation 1 [Hom... 29 9.3
gi|21327667 block of proliferation 1 [Homo sapiens] 29 9.3
>gi|189181666 hexosaminidase A preproprotein [Homo sapiens]
Length = 529
Score = 1104 bits (2856), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MTSSRLWFSLLLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSV 60
MTSSRLWFSLLLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSV
Sbjct: 1 MTSSRLWFSLLLAAAFAGRATALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSV 60
Query: 61 LDEAFQRYRDLLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTI 120
LDEAFQRYRDLLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTI
Sbjct: 61 LDEAFQRYRDLLFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTI 120
Query: 121 NDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHY 180
NDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHY
Sbjct: 121 NDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHY 180
Query: 181 LPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVK 240
LPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVK
Sbjct: 181 LPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVK 240
Query: 241 EVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEF 300
EVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEF
Sbjct: 241 EVIEYARLRGIRVLAEFDTPGHTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEF 300
Query: 301 MSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLL 360
MSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLL
Sbjct: 301 MSTFFLEVSSVFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLL 360
Query: 361 DIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPW 420
DIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPW
Sbjct: 361 DIVSSYGKGYVVWQEVFDNKVKIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPW 420
Query: 421 YLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAV 480
YLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAV
Sbjct: 421 YLNRISYGPDWKDFYIVEPLAFEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAV 480
Query: 481 AERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCEQEFEQT 529
AERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCEQEFEQT
Sbjct: 481 AERLWSNKLTSDLTFAYERLSHFRCELLRRGVQAQPLNVGFCEQEFEQT 529
>gi|4504373 hexosaminidase B preproprotein [Homo sapiens]
Length = 556
Score = 610 bits (1572), Expect = e-174
Identities = 287/504 (56%), Positives = 364/504 (72%), Gaps = 4/504 (0%)
Query: 22 ALWPWPQNFQTSDQRYVLYPNNFQFQYDVSSAAQPGCSVLDEAFQRYRDLLFGSGSWPRP 81
ALWP P + + + L P NF + +S A P C++L+EAF+RY +FG W
Sbjct: 55 ALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHE 114
Query: 82 YLTGKRHTLEKNVLVVSVVTPGCNQLPTLESVENYTLTINDDQCLLLSETVWGALRGLET 141
+ T + +LV + C+ P + S E+YTL + + +L + VWGALRGLET
Sbjct: 115 PAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLET 174
Query: 142 FSQLVWKSAEGTFFINKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVF 201
FSQLV++ + GTF IN++ I D PRF HRG+L+DTSRHYLP+ IL TLD MA+NK NV
Sbjct: 175 FSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVL 234
Query: 202 HWHLVDDPSFPYESFTFPELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPG 261
HWH+VDD SFPY+S TFPEL KGSY+ ++H+YT DV+ VIEYARLRGIRVL EFDTPG
Sbjct: 235 HWHIVDDQSFPYQSITFPELSNKGSYS-LSHVYTPNDVRMVIEYARLRGIRVLPEFDTPG 293
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFFLEVSSVFPDFYLHLGG 321
HTLSWG G LLTPCYS +FGP+NP+LN TY F++TFF E+S VFPD ++HLGG
Sbjct: 294 HTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGG 353
Query: 322 DEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDIVSSYGKGYVVWQEVFDNKV 381
DEV+F CW+SNP+IQDFMR+KGFG DFK+LESFYIQ +LDI+++ KG +VWQEVFD+K
Sbjct: 354 DEVEFKCWESNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKA 413
Query: 382 KIQPDTIIQVWREDIPVNYMKELELVTKAGFRALLSAPWYLNRISYGPDWKDFYIVEPLA 441
K+ P TI++VW++ Y +EL VT +GF +LSAPWYL+ ISYG DW+ +Y VEPL
Sbjct: 414 KLAPGTIVEVWKDSA---YPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLD 470
Query: 442 FEGTPEQKALVIGGEACMWGEYVDNTNLVPRLWPRAGAVAERLWSNKLTSDLTFAYERLS 501
F GT +QK L IGGEAC+WGEYVD TNL PRLWPRA AV ERLWS+K D+ AY+RL+
Sbjct: 471 FGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLT 530
Query: 502 HFRCELLRRGVQAQPLNVGFCEQE 525
RC ++ RG+ AQPL G+C E
Sbjct: 531 RHRCRMVERGIAAQPLYAGYCNHE 554
>gi|239742065 PREDICTED: hypothetical protein XP_002342402 [Homo
sapiens]
Length = 381
Score = 34.7 bits (78), Expect = 0.22
Identities = 13/27 (48%), Positives = 16/27 (59%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTFG 288
HT +WG G+P PC G+ P G FG
Sbjct: 320 HTGAWGTGLPASHVPCAPGALPQGAFG 346
>gi|239752588 PREDICTED: hypothetical protein XP_002348309, partial
[Homo sapiens]
Length = 327
Score = 33.1 bits (74), Expect = 0.64
Identities = 13/26 (50%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC GS P G F
Sbjct: 87 HTGAWGTGLPAPHVPCTPGSLPQGAF 112
>gi|239752515 PREDICTED: similar to double homeobox, 4 [Homo
sapiens]
Length = 479
Score = 32.7 bits (73), Expect = 0.84
Identities = 12/26 (46%), Positives = 16/26 (61%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC +G+ P G F
Sbjct: 239 HTGAWGMGLPAPQVPCETGALPQGVF 264
>gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo
sapiens]
Length = 483
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo
sapiens]
Length = 483
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|239744246 PREDICTED: hypothetical protein XP_002343082 [Homo
sapiens]
Length = 483
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|239744244 PREDICTED: similar to double homeobox, 4 [Homo
sapiens]
Length = 483
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo
sapiens]
Length = 483
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo
sapiens]
Length = 483
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|239742468 PREDICTED: double homeobox, 4-like [Homo sapiens]
Length = 485
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens]
Length = 483
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|194272172 double homeobox, 4 [Homo sapiens]
Length = 485
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|194272217 double homeobox, 4-like [Homo sapiens]
Length = 485
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|194272216 double homeobox, 4-like [Homo sapiens]
Length = 485
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|194272215 double homeobox, 4-like [Homo sapiens]
Length = 485
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|194272192 double homeobox, 4-like [Homo sapiens]
Length = 485
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTF 287
HT +WG G+P PC G+ P G F
Sbjct: 243 HTGAWGTGLPAPHVPCAPGALPQGAF 268
>gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor
[Homo sapiens]
Length = 639
Score = 30.8 bits (68), Expect = 3.2
Identities = 64/261 (24%), Positives = 94/261 (36%), Gaps = 46/261 (17%)
Query: 56 PGCSVLDEAFQRYRDL----LFGSGSWPRPYLTGKRHTLEKNVLVVSVVTPGCNQLPTLE 111
P +VLD +F R L L G G YL G E L ++TP P LE
Sbjct: 116 PALTVLDVSFNRLTSLPLGALRGLGELQELYLKGN----ELKTLPPGLLTP----TPKLE 167
Query: 112 --SVENYTLTI----------NDDQCLLLSETVWGALRGLETFSQLVWKSAEGTFFINKT 159
S+ N LT N D LL +++ +G L + G ++
Sbjct: 168 KLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNC 227
Query: 160 EIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDPSFPYESFTFP 219
EI F R+ L D + + +D + M N +V + P + Y P
Sbjct: 228 EILYFRRW-----LQDNAENVYVWKQGVD-VKAMTSNVASVQCDNSDKFPVYKYPGKGCP 281
Query: 220 ELMRKGSYNPVTHIYTAQDVKEVIEYARLRGIRVLAEFDTPGHTLSWG-----------P 268
L +G T +Y +E E ++R R + +F T HT WG
Sbjct: 282 TLGDEGD----TDLYDYYP-EEDTEGDKVRATRTVVKFPTKAHTTPWGLFYSWSTASLDS 336
Query: 269 GIPGLLTPCYSGSEPSGTFGP 289
+P L P ++ TF P
Sbjct: 337 QMPSSLHPTQESTKEQTTFPP 357
>gi|239758086 PREDICTED: similar to double homeobox, 4 [Homo
sapiens]
Length = 422
Score = 30.4 bits (67), Expect = 4.2
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 262 HTLSWGPGIPGLLTPCYSGSEPSGTFG 288
HT WG G+P PC + P+G FG
Sbjct: 182 HTGVWGTGLPPHHLPCVPAALPTGAFG 208
>gi|197100900 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 30.0 bits (66), Expect = 5.5
Identities = 12/38 (31%), Positives = 19/38 (50%)
Query: 268 PGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFF 305
PG+P P +G+ P G+ P +P L + S F+
Sbjct: 352 PGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFY 389
>gi|39930475 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 30.0 bits (66), Expect = 5.5
Identities = 12/38 (31%), Positives = 19/38 (50%)
Query: 268 PGIPGLLTPCYSGSEPSGTFGPVNPSLNNTYEFMSTFF 305
PG+P P +G+ P G+ P +P L + S F+
Sbjct: 352 PGLPAAAAPASTGAPPGGSPYPASPLLGRPLYYTSPFY 389
>gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]
Length = 334
Score = 30.0 bits (66), Expect = 5.5
Identities = 13/27 (48%), Positives = 17/27 (62%)
Query: 268 PGIPGLLTPCYSGSEPSGTFGPVNPSL 294
PG+P LL PC +G+ S GP P+L
Sbjct: 191 PGLPALLPPCATGALGSALRGPSLPAL 217
>gi|239743654 PREDICTED: similar to block of proliferation 1 [Homo
sapiens]
Length = 668
Score = 29.3 bits (64), Expect = 9.3
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
Query: 156 INKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDP 209
+ +E + FPH G LD R Y PL + D LD + +W V DP
Sbjct: 58 VGNVPLEWYDDFPHVGYDLDGRRIYKPLRT-RDELDQFLDKMDDPDYWRTVQDP 110
>gi|21327667 block of proliferation 1 [Homo sapiens]
Length = 746
Score = 29.3 bits (64), Expect = 9.3
Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 1/54 (1%)
Query: 156 INKTEIEDFPRFPHRGLLLDTSRHYLPLSSILDTLDVMAYNKLNVFHWHLVDDP 209
+ +E + FPH G LD R Y PL + D LD + +W V DP
Sbjct: 136 VGNVPLEWYDDFPHVGYDLDGRRIYKPLRT-RDELDQFLDKMDDPDYWRTVQDP 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,504,035
Number of Sequences: 37866
Number of extensions: 1022348
Number of successful extensions: 1906
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1881
Number of HSP's gapped (non-prelim): 25
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.