Guide to the Human Genome
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Name: HEXA Sequence: fasta or formatted (529aa) NCBI GI: 189181666
Description:

hexosaminidase A preproprotein

Referenced in:

Major Disease Loci
Protein Glycosylation
Lysosomes and Related Organelles

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.9         26           3
 C cysteine            1.5          8           1
 D aspartate           5.1         27           2
 E glutamate           6.8         36           1
 F phenylalanine       6.8         36           2
 G glycine             6.4         34           2
 H histidine           1.7          9           1
 I isoleucine          3.4         18           2
 K lysine              3.6         19           2
 L leucine            11.2         59           3
 M methionine          1.3          7           1
 N asparagine          4.2         22           2
 P proline             6.2         33           1
 Q glutamine           4.2         22           1
 R arginine            4.9         26           2
 S serine              7.0         37           2
 T threonine           6.2         33           1
 V valine              7.0         37           2
 W tryptophan          3.0         16           1
 Y tyrosine            4.5         24           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hexosaminidase A preproprotein 
HEXB                  0.542   hexosaminidase B preproprotein 
LOC100288801          0.009   PREDICTED: hypothetical protein XP_002342402 
LOC100290397          0.007   PREDICTED: hypothetical protein XP_002348309, parti...
HPX-2                 0.007   PREDICTED: similar to double homeobox, 4 
LOC440017             0.006   PREDICTED: similar to double homeobox, 4 
LOC728022             0.006   PREDICTED: similar to double homeobox, 4 
LOC100289581          0.006   PREDICTED: hypothetical protein XP_002343082 
LOC440014             0.006   PREDICTED: similar to double homeobox, 4 
LOC399839             0.006   PREDICTED: similar to double homeobox, 4 
LOC440013             0.006   PREDICTED: similar to double homeobox, 4 
LOC653548             0.006   PREDICTED: double homeobox, 4-like 
LOC441056             0.006   PREDICTED: double homeobox, 4-like 
DUX4                  0.006   double homeobox, 4 
LOC728410             0.006   double homeobox, 4-like 
LOC653543             0.006   double homeobox, 4-like 
LOC653545             0.006   double homeobox, 4-like 
LOC653544             0.006   double homeobox, 4-like 
GP1BA                 0.006   platelet glycoprotein Ib alpha polypeptide precurso...
HPX-2                 0.005   PREDICTED: similar to double homeobox, 4 
IRX2                  0.005   iroquois homeobox 2 
IRX2                  0.005   iroquois homeobox 2 
VAX1                  0.005   ventral anterior homeobox 1 isoform a 
LOC727967             0.004   PREDICTED: similar to block of proliferation 1 [Hom...
BOP1                  0.004   block of proliferation 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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