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Search of human proteins with 189083846
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189083846 insulin-like growth factor 2 isoform 2 [Homo
sapiens]
(236 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens] 481 e-136
gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Hom... 373 e-104
gi|108796063 insulin-like growth factor 2 isoform 1 precursor [H... 373 e-104
gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein... 94 1e-19
gi|163659903 insulin-like growth factor 1 isoform 3 preproprotei... 94 1e-19
gi|163659901 insulin-like growth factor 1 isoform 2 preproprotei... 94 1e-19
gi|163659899 insulin-like growth factor 1 isoform 1 preproprotei... 94 1e-19
gi|4557671 proinsulin precursor [Homo sapiens] 52 3e-07
gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens] 39 0.005
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 30 2.4
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 30 2.4
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 30 2.4
gi|71725371 solute carrier family 10 (sodium/bile acid cotranspo... 29 4.0
gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens] 28 6.9
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens] 28 6.9
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 28 9.0
>gi|189083846 insulin-like growth factor 2 isoform 2 [Homo sapiens]
Length = 236
Score = 481 bits (1237), Expect = e-136
Identities = 236/236 (100%), Positives = 236/236 (100%)
Query: 1 MVSPDPQIIVVAPETELASMQVQRTEDGVTIIQIFWVGRKGELLRRTPVSSAMQTPMGIP 60
MVSPDPQIIVVAPETELASMQVQRTEDGVTIIQIFWVGRKGELLRRTPVSSAMQTPMGIP
Sbjct: 1 MVSPDPQIIVVAPETELASMQVQRTEDGVTIIQIFWVGRKGELLRRTPVSSAMQTPMGIP 60
Query: 61 MGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR 120
MGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR
Sbjct: 61 MGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR 120
Query: 121 GIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQ 180
GIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQ
Sbjct: 121 GIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQ 180
Query: 181 RLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 236
RLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 181 RLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 236
>gi|4504609 insulin-like growth factor 2 isoform 1 precursor [Homo
sapiens]
Length = 180
Score = 373 bits (957), Expect = e-104
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 57 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 116
MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
Query: 117 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 176
RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 61 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
Query: 177 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 236
QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
>gi|108796063 insulin-like growth factor 2 isoform 1 precursor [Homo
sapiens]
Length = 180
Score = 373 bits (957), Expect = e-104
Identities = 180/180 (100%), Positives = 180/180 (100%)
Query: 57 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 116
MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
Sbjct: 1 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 60
Query: 117 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 176
RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
Sbjct: 61 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 120
Query: 177 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 236
QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Sbjct: 121 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 180
>gi|11024682 insulin-like growth factor 1 isoform 4 preproprotein
[Homo sapiens]
Length = 153
Score = 93.6 bits (231), Expect = 1e-19
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 66 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 121
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 37 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
Query: 122 IVEECCFRSCDLALLETYCA--TPAKSERDV 150
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 91 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
>gi|163659903 insulin-like growth factor 1 isoform 3 preproprotein
[Homo sapiens]
Length = 195
Score = 93.6 bits (231), Expect = 1e-19
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 66 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 121
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 37 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
Query: 122 IVEECCFRSCDLALLETYCA--TPAKSERDV 150
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 91 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
>gi|163659901 insulin-like growth factor 1 isoform 2 preproprotein
[Homo sapiens]
Length = 137
Score = 93.6 bits (231), Expect = 1e-19
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 66 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 121
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 21 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 74
Query: 122 IVEECCFRSCDLALLETYCA--TPAKSERDV 150
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 75 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 105
>gi|163659899 insulin-like growth factor 1 isoform 1 preproprotein
[Homo sapiens]
Length = 158
Score = 93.6 bits (231), Expect = 1e-19
Identities = 53/91 (58%), Positives = 58/91 (63%), Gaps = 12/91 (13%)
Query: 66 LVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSR----G 121
L LLTF + A+ ETLCG ELVD LQFVCGDRGFYF++P S R G
Sbjct: 37 LCLLTFTSSATA------GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTG 90
Query: 122 IVEECCFRSCDLALLETYCA--TPAKSERDV 150
IV+ECCFRSCDL LE YCA PAKS R V
Sbjct: 91 IVDECCFRSCDLRRLEMYCAPLKPAKSARSV 121
>gi|4557671 proinsulin precursor [Homo sapiens]
Length = 110
Score = 52.4 bits (124), Expect = 3e-07
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 27/103 (26%)
Query: 65 MLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRV--------- 115
+L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQV 66
Query: 116 ------------------SRRSRGIVEECCFRSCDLALLETYC 140
S + RGIVE+CC C L LE YC
Sbjct: 67 ELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYC 109
>gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]
Length = 200
Score = 38.5 bits (88), Expect = 0.005
Identities = 20/50 (40%), Positives = 28/50 (56%)
Query: 65 MLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASR 114
+L LL LA AA ++ LCG LV+ L VCG+RGF+++ R
Sbjct: 7 LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRR 56
>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 29.6 bits (65), Expect = 2.4
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 184 RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 225
RG PAL R GH + +K L+A + HR L T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711
>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 29.6 bits (65), Expect = 2.4
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 184 RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 225
RG PAL R GH + +K L+A + HR L T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711
>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 29.6 bits (65), Expect = 2.4
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 184 RGLPALLRARRGH----VLAKELEAFREAKRHRPLIALPTQDPAHG 225
RG PAL R GH + +K L+A + HR L T+ P HG
Sbjct: 1666 RGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHG 1711
>gi|71725371 solute carrier family 10 (sodium/bile acid
cotransporter family), member 7 isoform b [Homo sapiens]
Length = 340
Score = 28.9 bits (63), Expect = 4.0
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 57 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQ--FVCGDRGFYFSRP 111
+GIPM K + L+ S + Y P++ L G LV T++ V +G +RP
Sbjct: 282 LGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRP 338
>gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens]
Length = 2322
Score = 28.1 bits (61), Expect = 6.9
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
Query: 189 LLRARRGHVLAKELEAFREAKRHR--PLIALPTQDPAHGGAP-PEM 231
+L A+ + LA + E FR+ + + PL A+P Q P GG P PE+
Sbjct: 2259 VLTAKPRNGLAGDTETFRKVEPGQAIPLTAVPGQGPPPGGQPDPEL 2304
>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
Length = 268
Score = 28.1 bits (61), Expect = 6.9
Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 7/80 (8%)
Query: 107 YFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPV 166
YF+ S SR G+ CC + ++ T C A+ + +V + Y
Sbjct: 167 YFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVI-------YTK 219
Query: 167 GKFFQYDTWKQSTQRLRRGL 186
G Q++ W Q + G+
Sbjct: 220 GCVPQFEKWLQDNLTIVAGI 239
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 27.7 bits (60), Expect = 9.0
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 8/67 (11%)
Query: 176 KQSTQRLRRGLPALLRARRGHVLAKELEAFREAKR-------HRPLIALPTQDPAHGGAP 228
++ + + R+ LPA RAR A EL +A+ HRP P+ P H P
Sbjct: 433 RERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGH-TLP 491
Query: 229 PEMASNR 235
P+ S R
Sbjct: 492 PKPPSPR 498
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,989,192
Number of Sequences: 37866
Number of extensions: 447714
Number of successful extensions: 941
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 927
Number of HSP's gapped (non-prelim): 17
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.