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Search of human proteins with 103472011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a
[Homo sapiens]
(471 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Hom... 929 0.0
gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Hom... 748 0.0
gi|221136809 lactate dehydrogenase A-like 6A [Homo sapiens] 239 3e-63
gi|47059044 lactate dehydrogenase A-like 6A [Homo sapiens] 239 3e-63
gi|4557032 L-lactate dehydrogenase B [Homo sapiens] 230 2e-60
gi|15082234 lactate dehydrogenase A-like 6B [Homo sapiens] 229 5e-60
gi|5031857 L-lactate dehydrogenase A isoform 1 [Homo sapiens] 227 2e-59
gi|9257228 L-lactate dehydrogenase C [Homo sapiens] 220 2e-57
gi|4504973 L-lactate dehydrogenase C [Homo sapiens] 220 2e-57
gi|5454140 tumor susceptibility gene 101 [Homo sapiens] 172 8e-43
gi|207028494 L-lactate dehydrogenase A isoform 2 [Homo sapiens] 158 9e-39
gi|38505226 E2F family member 8 [Homo sapiens] 32 1.6
gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens] 31 2.8
gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens] 31 2.8
gi|68989263 enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A... 30 6.2
gi|31077081 frataxin isoform 1 preproprotein [Homo sapiens] 29 8.1
gi|226437568 apoptosis-inducing factor, mitochondrion-associated... 29 8.1
gi|65787454 apoptosis-inducing factor, mitochondrion-associated,... 29 8.1
gi|21389617 apoptosis-inducing factor, mitochondrion-associated,... 29 8.1
>gi|103472011 ubiquitin-conjugating enzyme E2-like isoform a [Homo
sapiens]
Length = 471
Score = 929 bits (2401), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP 60
MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP
Sbjct: 1 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP 60
Query: 61 VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP 120
VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP
Sbjct: 61 VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP 120
Query: 121 KSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENK 180
KSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENK
Sbjct: 121 KSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENK 180
Query: 181 TVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDL 240
TVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDL
Sbjct: 181 TVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDL 240
Query: 241 SASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMT 300
SASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMT
Sbjct: 241 SASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMT 300
Query: 301 YVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQ 360
YVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQ
Sbjct: 301 YVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQ 360
Query: 361 EEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYD 420
EEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYD
Sbjct: 361 EEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYD 420
Query: 421 INSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLKL 471
INSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLKL
Sbjct: 421 INSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLKL 471
>gi|103472015 ubiquitin-conjugating enzyme E2-like isoform b [Homo
sapiens]
Length = 379
Score = 748 bits (1932), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP 60
MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP
Sbjct: 1 MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIP 60
Query: 61 VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP 120
VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP
Sbjct: 61 VMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHP 120
Query: 121 KSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENK 180
KSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENK
Sbjct: 121 KSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENK 180
Query: 181 TVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDL 240
TVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDL
Sbjct: 181 TVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDL 240
Query: 241 SASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMT 300
SASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMT
Sbjct: 241 SASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMT 300
Query: 301 YVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQ 360
YVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQ
Sbjct: 301 YVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQ 360
Query: 361 EEVVSHTSQVQLSNR 375
EEVVSHTSQVQLSNR
Sbjct: 361 EEVVSHTSQVQLSNR 375
>gi|221136809 lactate dehydrogenase A-like 6A [Homo sapiens]
Length = 332
Score = 239 bits (611), Expect = 3e-63
Identities = 133/326 (40%), Positives = 197/326 (60%), Gaps = 29/326 (8%)
Query: 172 KSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGT-KGATMDLE--- 227
K++A E NKI++VG G +G+AC ++I KG++D LVL+D+ EG KG TMDL+
Sbjct: 10 KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69
Query: 228 -IFNLPNVEISKDLSASAHSKVVIFTVNSLGSS-QSYLDVVQSNVDMFRALVPALGHYSQ 285
+PN+ SKD +A+S +VI T + ++ LD+VQ NV +F+ ++P + YS
Sbjct: 70 PFMKMPNIVSSKDYLVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSP 129
Query: 286 HSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWV 345
H LL+ + PV+I+TYV WKLS FP NRVIG GCNLDS R +Y I L + +
Sbjct: 130 HCKLLIVTNPVDILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLI 189
Query: 346 IGEQGEDKVLTWSG-----------QEEVVSHTSQVQLSN-------RAMELLRVKGQRS 387
+GE G+ V WSG ++ + Q N E++++KG S
Sbjct: 190 LGEHGDSSVPVWSGVNIAGVPLKDLNPDIGTDKDPEQWENVHKKVISSGYEMVKMKGYTS 249
Query: 388 WSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKT--T 445
W + LSVAD+ +SI+ N ++VH VS L+KG Y IN ++FLS+PCILG NG++++IK T
Sbjct: 250 WGISLSVADLTESILKNLRRVHPVSTLSKGLYGINEDIFLSVPCILGENGITDLIKVKLT 309
Query: 446 LKEDTVTEKLQSSASSIHSLQQQLKL 471
L+E+ LQ SA ++ +Q++LKL
Sbjct: 310 LEEEAC---LQKSAETLWEIQKELKL 332
>gi|47059044 lactate dehydrogenase A-like 6A [Homo sapiens]
Length = 332
Score = 239 bits (611), Expect = 3e-63
Identities = 133/326 (40%), Positives = 197/326 (60%), Gaps = 29/326 (8%)
Query: 172 KSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGT-KGATMDLE--- 227
K++A E NKI++VG G +G+AC ++I KG++D LVL+D+ EG KG TMDL+
Sbjct: 10 KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69
Query: 228 -IFNLPNVEISKDLSASAHSKVVIFTVNSLGSS-QSYLDVVQSNVDMFRALVPALGHYSQ 285
+PN+ SKD +A+S +VI T + ++ LD+VQ NV +F+ ++P + YS
Sbjct: 70 PFMKMPNIVSSKDYLVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYSP 129
Query: 286 HSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWV 345
H LL+ + PV+I+TYV WKLS FP NRVIG GCNLDS R +Y I L + +
Sbjct: 130 HCKLLIVTNPVDILTYVAWKLSGFPKNRVIGSGCNLDSARFRYFIGQRLGIHSESCHGLI 189
Query: 346 IGEQGEDKVLTWSG-----------QEEVVSHTSQVQLSN-------RAMELLRVKGQRS 387
+GE G+ V WSG ++ + Q N E++++KG S
Sbjct: 190 LGEHGDSSVPVWSGVNIAGVPLKDLNPDIGTDKDPEQWENVHKKVISSGYEMVKMKGYTS 249
Query: 388 WSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKT--T 445
W + LSVAD+ +SI+ N ++VH VS L+KG Y IN ++FLS+PCILG NG++++IK T
Sbjct: 250 WGISLSVADLTESILKNLRRVHPVSTLSKGLYGINEDIFLSVPCILGENGITDLIKVKLT 309
Query: 446 LKEDTVTEKLQSSASSIHSLQQQLKL 471
L+E+ LQ SA ++ +Q++LKL
Sbjct: 310 LEEEAC---LQKSAETLWEIQKELKL 332
>gi|4557032 L-lactate dehydrogenase B [Homo sapiens]
Length = 334
Score = 230 bits (586), Expect = 2e-60
Identities = 126/314 (40%), Positives = 190/314 (60%), Gaps = 29/314 (9%)
Query: 183 NKITVVGGGELGIACTLAISAKGIADRLVLLD-LSEGTKGATMDLEIFNL----PNVEIS 237
NKITVVG G++G+AC ++I K +AD L L+D L + KG MDL+ +L P +
Sbjct: 22 NKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVAD 81
Query: 238 KDLSASAHSKVVIFTVN-SLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPV 296
KD S +A+SK+V+ T +S L++VQ NV++F+ ++P + YS +++V S PV
Sbjct: 82 KDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPV 141
Query: 297 EIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLT 356
+I+TYVTWKLS P +RVIG GCNLDS R +Y++ L S W++GE G+ V
Sbjct: 142 DILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAV 201
Query: 357 WSGQEEVVSHTSQVQLS--------------------NRAMELLRVKGQRSWSVGLSVAD 396
WSG V+ S +L+ A E++++KG +W++GLSVAD
Sbjct: 202 WSGVN--VAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVAD 259
Query: 397 MVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQ 456
+++S++ N ++H VS + KG Y I +EVFLSLPCIL G++ VI LK+D V + L+
Sbjct: 260 LIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQ-LK 318
Query: 457 SSASSIHSLQQQLK 470
SA ++ +Q+ LK
Sbjct: 319 KSADTLWDIQKDLK 332
>gi|15082234 lactate dehydrogenase A-like 6B [Homo sapiens]
Length = 381
Score = 229 bits (583), Expect = 5e-60
Identities = 120/313 (38%), Positives = 189/313 (60%), Gaps = 25/313 (7%)
Query: 183 NKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGT-KGATMDLE----IFNLPNVEIS 237
+K++++G G +G+AC ++I KG++D L L+DL E KG TMDL+ +PN+ S
Sbjct: 70 SKVSIIGTGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPFTKMPNIVCS 129
Query: 238 KDLSASAHSKVVIFTVNSLGSS-QSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPV 296
KD +A+S +VI T + ++ L++VQ NV +F+ ++ ++ YS H L++ S PV
Sbjct: 130 KDYFVTANSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHCKLIIVSNPV 189
Query: 297 EIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLT 356
+I+TYV WKLS FP NR+IG GCNLD+ R +++I L + W++GE G+ V
Sbjct: 190 DILTYVAWKLSAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILGEHGDSSVPV 249
Query: 357 WSG-----------QEEVVSHTSQVQLSN-------RAMELLRVKGQRSWSVGLSVADMV 398
WSG ++ + Q N A E++++KG SW++GLSVAD+
Sbjct: 250 WSGVNIAGVPLKDLNSDIGTDKDPEQWKNVHKEVTATAYEIIKMKGYTSWAIGLSVADLT 309
Query: 399 DSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSS 458
+SI+ N +++H VS + KG Y I+ EVFLS+PCILG NG++ +IK L + L+ S
Sbjct: 310 ESILKNLRRIHPVSTIIKGLYGIDEEVFLSIPCILGENGITNLIKIKLTPEEEAH-LKKS 368
Query: 459 ASSIHSLQQQLKL 471
A ++ +Q +LKL
Sbjct: 369 AKTLWEIQNKLKL 381
>gi|5031857 L-lactate dehydrogenase A isoform 1 [Homo sapiens]
Length = 332
Score = 227 bits (578), Expect = 2e-59
Identities = 126/317 (39%), Positives = 191/317 (60%), Gaps = 25/317 (7%)
Query: 178 ENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGT-KGATMDLEIFNL----P 232
E NKITVVG G +G+AC ++I K +AD L L+D+ E KG MDL+ +L P
Sbjct: 16 EQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTP 75
Query: 233 NVEISKDLSASAHSKVVIFTVNSLGSS-QSYLDVVQSNVDMFRALVPALGHYSQHSVLLV 291
+ KD + +A+SK+VI T + +S L++VQ NV++F+ ++P + YS + LL+
Sbjct: 76 KIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLI 135
Query: 292 ASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGE 351
S PV+I+TYV WK+S FP NRVIG GCNLDS R +Y++ L WV+GE G+
Sbjct: 136 VSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGD 195
Query: 352 DKVLTWSG------------------QEEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLS 393
V WSG +++ Q+ A E++++KG SW++GLS
Sbjct: 196 SSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLS 255
Query: 394 VADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTE 453
VAD+ +SI+ N ++VH VS + KG Y I +VFLS+PCILG NG+S+++K TL +
Sbjct: 256 VADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEE-EA 314
Query: 454 KLQSSASSIHSLQQQLK 470
+L+ SA ++ +Q++L+
Sbjct: 315 RLKKSADTLWGIQKELQ 331
>gi|9257228 L-lactate dehydrogenase C [Homo sapiens]
Length = 332
Score = 220 bits (560), Expect = 2e-57
Identities = 120/310 (38%), Positives = 182/310 (58%), Gaps = 25/310 (8%)
Query: 184 KITVVGGGELGIACTLAISAKGIADRLVLLDLS-EGTKGATMDLE----IFNLPNVEISK 238
KIT+VG G +G+AC ++I K +AD L L+D++ + KG MDL+ F+ + K
Sbjct: 22 KITIVGTGAVGMACAISILLKDLADELALVDVALDKLKGEMMDLQHGSLFFSTSKITSGK 81
Query: 239 DLSASAHSKVVIFTVNSLGSS-QSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVE 297
D S SA+S++VI T + ++ L +VQ NV + ++++PA+ HYS +LV S PV+
Sbjct: 82 DYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVD 141
Query: 298 IMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTW 357
I+TY+ WK+S P RVIG GCNLDS R +Y+I L + W+IGE G+ V W
Sbjct: 142 ILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLW 201
Query: 358 S----------------GQEEVVSHTSQV--QLSNRAMELLRVKGQRSWSVGLSVADMVD 399
S G + H + Q+ A E++++KG SW++GLSV D+V
Sbjct: 202 SGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVG 261
Query: 400 SIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSA 459
SI+ N ++VH VS + KG Y I E+FLS+PC+LG NGVS+V+K L + + SA
Sbjct: 262 SILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLNSEE-EALFKKSA 320
Query: 460 SSIHSLQQQL 469
++ ++Q+ L
Sbjct: 321 ETLWNIQKDL 330
>gi|4504973 L-lactate dehydrogenase C [Homo sapiens]
Length = 332
Score = 220 bits (560), Expect = 2e-57
Identities = 120/310 (38%), Positives = 182/310 (58%), Gaps = 25/310 (8%)
Query: 184 KITVVGGGELGIACTLAISAKGIADRLVLLDLS-EGTKGATMDLE----IFNLPNVEISK 238
KIT+VG G +G+AC ++I K +AD L L+D++ + KG MDL+ F+ + K
Sbjct: 22 KITIVGTGAVGMACAISILLKDLADELALVDVALDKLKGEMMDLQHGSLFFSTSKITSGK 81
Query: 239 DLSASAHSKVVIFTVNSLGSS-QSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVE 297
D S SA+S++VI T + ++ L +VQ NV + ++++PA+ HYS +LV S PV+
Sbjct: 82 DYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVD 141
Query: 298 IMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTW 357
I+TY+ WK+S P RVIG GCNLDS R +Y+I L + W+IGE G+ V W
Sbjct: 142 ILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLW 201
Query: 358 S----------------GQEEVVSHTSQV--QLSNRAMELLRVKGQRSWSVGLSVADMVD 399
S G + H + Q+ A E++++KG SW++GLSV D+V
Sbjct: 202 SGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVG 261
Query: 400 SIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSA 459
SI+ N ++VH VS + KG Y I E+FLS+PC+LG NGVS+V+K L + + SA
Sbjct: 262 SILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLNSEE-EALFKKSA 320
Query: 460 SSIHSLQQQL 469
++ ++Q+ L
Sbjct: 321 ETLWNIQKDL 330
>gi|5454140 tumor susceptibility gene 101 [Homo sapiens]
Length = 390
Score = 172 bits (435), Expect = 8e-43
Identities = 76/136 (55%), Positives = 103/136 (75%)
Query: 8 LRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIPVMYQGNT 67
L++++ KYK+RDLTV E NV + K +D+YVF D S ++L+N TGTIPV Y+GNT
Sbjct: 8 LKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNT 67
Query: 68 YNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGL 127
YNIPI W+LD++P+ PPICF+KPT++M I GKHVDA G+IYLPYL W HP+S ++GL
Sbjct: 68 YNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGL 127
Query: 128 IKEMIAKFQEELPMYS 143
I+ MI F +E P++S
Sbjct: 128 IQVMIVVFGDEPPVFS 143
>gi|207028494 L-lactate dehydrogenase A isoform 2 [Homo sapiens]
Length = 274
Score = 158 bits (400), Expect = 9e-39
Identities = 97/311 (31%), Positives = 150/311 (48%), Gaps = 71/311 (22%)
Query: 178 ENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEIS 237
E NKITVVG G +G+AC ++I K +AD +L + ++ ++
Sbjct: 16 EQTPQNKITVVGVGAVGMACAISILMKDLAD----------------ELALVDVIEDKLK 59
Query: 238 KDLSASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVE 297
++ H + + T + S V+
Sbjct: 60 GEMMDLQHGSLFLRTPK------------------------------------IVSGKVD 83
Query: 298 IMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTW 357
I+TYV WK+S FP NRVIG GCNLDS R +Y++ L WV+GE G+ V W
Sbjct: 84 ILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVW 143
Query: 358 SGQEEVVSHTSQV------------------QLSNRAMELLRVKGQRSWSVGLSVADMVD 399
SG + Q+ A E++++KG SW++GLSVAD+ +
Sbjct: 144 SGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAE 203
Query: 400 SIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSA 459
SI+ N ++VH VS + KG Y I +VFLS+PCILG NG+S+++K TL + +L+ SA
Sbjct: 204 SIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEE-EARLKKSA 262
Query: 460 SSIHSLQQQLK 470
++ +Q++L+
Sbjct: 263 DTLWGIQKELQ 273
>gi|38505226 E2F family member 8 [Homo sapiens]
Length = 867
Score = 31.6 bits (70), Expect = 1.6
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 15/101 (14%)
Query: 325 RLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQE--------EVVSHTSQVQL---- 372
R Y I NVL + K+V V E+G W+G E V H + L
Sbjct: 313 RRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSSPVIHFTPSDLEVRR 372
Query: 373 ---SNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHS 410
N A L +G+ +++ S+ +V SI ++++K++S
Sbjct: 373 SSKENCAKNLFSTRGKPNFTRHPSLIKLVKSIESDRRKINS 413
>gi|22202629 programmed cell death 8 isoform 2 [Homo sapiens]
Length = 609
Score = 30.8 bits (68), Expect = 2.8
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 179 NKTVNKITVVGGGELG--IACTLAISAKGIADRLVLLDLSEGTKG 221
++ V IT++GGG LG +AC L A+ + ++ L +G G
Sbjct: 293 SREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMG 337
>gi|4757732 programmed cell death 8 isoform 1 [Homo sapiens]
Length = 613
Score = 30.8 bits (68), Expect = 2.8
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 179 NKTVNKITVVGGGELG--IACTLAISAKGIADRLVLLDLSEGTKG 221
++ V IT++GGG LG +AC L A+ + ++ L +G G
Sbjct: 297 SREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMG 341
>gi|68989263 enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A
dehydrogenase [Homo sapiens]
Length = 723
Score = 29.6 bits (65), Expect = 6.2
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 5/116 (4%)
Query: 130 EMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENKTVNKITVVG 189
E+ K +EEL +Y L S +AR + + + S + SW + V+ + VVG
Sbjct: 246 EVGIKKEEELFLYLLQSG-QARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVG 304
Query: 190 GGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAH 245
G +G ++ + I ++ +D S+ + AT + I ++ E SK + S H
Sbjct: 305 LGTMGRGIVISFARARIP--VIAVD-SDKNQLATANKMITSVLEKEASK-MQQSGH 356
>gi|31077081 frataxin isoform 1 preproprotein [Homo sapiens]
Length = 210
Score = 29.3 bits (64), Expect = 8.1
Identities = 12/36 (33%), Positives = 18/36 (50%)
Query: 331 TNVLKAQTSGKEVWVIGEQGEDKVLTWSGQEEVVSH 366
T V+ QT K++W+ K W+G+ V SH
Sbjct: 142 TYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSH 177
>gi|226437568 apoptosis-inducing factor, mitochondrion-associated, 3
isoform 3 [Homo sapiens]
Length = 604
Score = 29.3 bits (64), Expect = 8.1
Identities = 11/31 (35%), Positives = 18/31 (58%)
Query: 185 ITVVGGGELGIACTLAISAKGIADRLVLLDL 215
+ +VG G G+ C + +G +DR+VL L
Sbjct: 203 VLIVGAGAAGLVCAETLRQEGFSDRIVLCTL 233
>gi|65787454 apoptosis-inducing factor, mitochondrion-associated, 3
isoform 2 [Homo sapiens]
Length = 598
Score = 29.3 bits (64), Expect = 8.1
Identities = 11/31 (35%), Positives = 18/31 (58%)
Query: 185 ITVVGGGELGIACTLAISAKGIADRLVLLDL 215
+ +VG G G+ C + +G +DR+VL L
Sbjct: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVLCTL 227
>gi|21389617 apoptosis-inducing factor, mitochondrion-associated, 3
isoform 1 [Homo sapiens]
Length = 605
Score = 29.3 bits (64), Expect = 8.1
Identities = 11/31 (35%), Positives = 18/31 (58%)
Query: 185 ITVVGGGELGIACTLAISAKGIADRLVLLDL 215
+ +VG G G+ C + +G +DR+VL L
Sbjct: 197 VLIVGAGAAGLVCAETLRQEGFSDRIVLCTL 227
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,994,830
Number of Sequences: 37866
Number of extensions: 654912
Number of successful extensions: 1561
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1522
Number of HSP's gapped (non-prelim): 21
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.