Search of human proteins with 183227691

Search of human proteins with 183227691

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|183227691 proline dehydrogenase 1 [Homo sapiens]
         (600 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|183227691 proline dehydrogenase 1 [Homo sapiens]                  1204   0.0  
gi|10864043 kidney and liver proline oxidase 1 [Homo sapiens]         220   3e-57
gi|222352143 TBC1 domain family, member 2 [Homo sapiens]               42   0.002
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    34   0.44 
gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens]      32   1.3  
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     32   1.3  
gi|156105697 ring finger and CCCH-type zinc finger domains 2 iso...    32   1.7  
gi|156105699 ring finger and CCCH-type zinc finger domains 2 iso...    32   1.7  
gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2 [Homo...    31   2.8  
gi|94966757 protein disulfide isomerase A2 [Homo sapiens]              31   3.7  
gi|41406086 semaphorin 3D [Homo sapiens]                               31   3.7  
gi|189027129 phosphodiesterase 12 [Homo sapiens]                       30   6.3  
gi|39812378 RAN binding protein 9 [Homo sapiens]                       30   8.3  
gi|74271816 radical fringe [Homo sapiens]                              30   8.3  
gi|40548415 dishevelled associated activator of morphogenesis 2 ...    30   8.3  

>gi|183227691 proline dehydrogenase 1 [Homo sapiens]
          Length = 600

 Score = 1204 bits (3116), Expect = 0.0
 Identities = 600/600 (100%), Positives = 600/600 (100%)

Query: 1   MALRRALPALRPCIPRFVPLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDFGNAQE 60
           MALRRALPALRPCIPRFVPLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDFGNAQE
Sbjct: 1   MALRRALPALRPCIPRFVPLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDFGNAQE 60

Query: 61  AYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAG 120
           AYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAG
Sbjct: 61  AYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAG 120

Query: 121 EDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQ 180
           EDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQ
Sbjct: 121 EDQESIQPLLRHYRAFGVSAILDYGVEEDLSPEEAEHKEMESCTSAAERDGSGTNKRDKQ 180

Query: 181 YQAHWAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEASGRVSDDGFIAIKLTALGR 240
           YQAHWAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEASGRVSDDGFIAIKLTALGR
Sbjct: 181 YQAHWAFGDRRNGVISARTYFYANEAKCDSHMETFLRCIEASGRVSDDGFIAIKLTALGR 240

Query: 241 PQFLLQFSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDW 300
           PQFLLQFSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDW
Sbjct: 241 PQFLLQFSEVLAKWRCFFHQMAVEQGQAGLAAMDTKLEVAVLQESVAKLGIASRAEIEDW 300

Query: 301 FTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRML 360
           FTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRML
Sbjct: 301 FTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRML 360

Query: 361 QRMDVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEKPLIFNTYQCYLKDAY 420
           QRMDVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEKPLIFNTYQCYLKDAY
Sbjct: 361 QRMDVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEKPLIFNTYQCYLKDAY 420

Query: 421 DNVTLDVELARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDY 480
           DNVTLDVELARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDY
Sbjct: 421 DNVTLDVELARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDY 480

Query: 481 VLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQ 540
           VLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQ
Sbjct: 481 VLEELKHNAKAKVMVASHNEDTVRFALRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQ 540

Query: 541 AGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLRRLRTGNLFHRPA 600
           AGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLRRLRTGNLFHRPA
Sbjct: 541 AGYPVYKYVPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLRRLRTGNLFHRPA 600


>gi|10864043 kidney and liver proline oxidase 1 [Homo sapiens]
          Length = 536

 Score =  220 bits (560), Expect = 3e-57
 Identities = 129/285 (45%), Positives = 170/285 (59%), Gaps = 6/285 (2%)

Query: 313 DLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRMLQRMDVLAKKATE 372
           +L  W     +  +LS   +     +GQ    +S    E+   +   L R+  +A+ A  
Sbjct: 248 ELASWVRRPGASLELSPERLAEAMDSGQ-NLQVSCLNAEQNQHLRASLSRLHRVAQYARA 306

Query: 373 MGVRLMVDAEQTYFQPAISRLTLEMQRKFNVEK---PLIFNTYQCYLKDAYDNVTLDVEL 429
             VRL+VDAE T   PA+S L   +  ++N      P ++NTYQ  LKD ++ +  D E 
Sbjct: 307 QHVRLLVDAEYTSLNPALSLLVAALAVRWNSPGEGGPWVWNTYQACLKDTFERLGRDAEA 366

Query: 430 ARREGWCFGAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDYVLEEL-KHN 488
           A R G  FG KLVRGAYL +ERA A   G EDP  P YEAT+  Y RCL+ +L  + +H 
Sbjct: 367 AHRAGLAFGVKLVRGAYLDKERAVAQLHGMEDPTQPDYEATSQSYSRCLELMLTHVARHG 426

Query: 489 AKAKVMVASHNEDTVRFALRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQAGYPVYKY 548
               +MVASHNE++VR A +RM ELG+ P D  V FGQLLGMCD +S  LGQAGY VYK 
Sbjct: 427 PMCHLMVASHNEESVRQATKRMWELGI-PLDGTVCFGQLLGMCDHVSLALGQAGYVVYKS 485

Query: 549 VPYGPVMEVLPYLSRRALENSSLMKGTHRERQLLWLELLRRLRTG 593
           +PYG + EV+PYL RRA EN S+++G  RE++LL  EL RRL  G
Sbjct: 486 IPYGSLEEVIPYLIRRAQENRSVLQGARREQELLSQELWRRLLPG 530



 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 36/89 (40%), Positives = 51/89 (57%)

Query: 61  AYRSRRTWELARSLLVLRLCAWPALLARHEQLLYVSRKLLGQRLFNKLMKMTFYGHFVAG 120
           A+  + T EL R+LLVLRLCAWP L+     L   SR+LLG RL    ++ + YG FVAG
Sbjct: 104 AFHLKGTGELTRALLVLRLCAWPPLVTHGLLLQAWSRRLLGSRLSGAFLRASVYGQFVAG 163

Query: 121 EDQESIQPLLRHYRAFGVSAILDYGVEED 149
           E  E ++  ++  R   +  +L    EE+
Sbjct: 164 ETAEEVKGCVQQLRTLSLRPLLAVPTEEE 192


>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
          Length = 917

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 12/125 (9%)

Query: 19  PLSTAPASREQPAAGPAAVPGGGSATAVRP-PVPAVDFGNAQEAYRSRRTWELARSLLVL 77
           P S  P   EQP A  A+ PG     + +P P P++    AQ+A R   T+      +  
Sbjct: 241 PQSGEPQREEQPLASDASTPGREPEDSPKPAPKPSLTISFAQKAKRQNNTFPFFSEGITR 300

Query: 78  RLCAWPALLARHEQLLYVSRKLLGQRLFNKLM----------KMTFYGHFVAGEDQESIQ 127
              A   + A  +Q+L ++++L  Q+   K++          K     +  A ED++ ++
Sbjct: 301 NRTAQEKVAALEQQVLMLTKELKSQKELVKILHKALEAAQQEKRASSAYLAAAEDKDRLE 360

Query: 128 PLLRH 132
            L+RH
Sbjct: 361 -LVRH 364


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 33.9 bits (76), Expect = 0.44
 Identities = 43/206 (20%), Positives = 82/206 (39%), Gaps = 17/206 (8%)

Query: 342  EPLLSRFTEEEELQMTRMLQRM----DVLAKKATEMGVRLMVDAEQTYFQPAISRLTLEM 397
            EP +  + ++ +L   + LQ+     +   K   E G  L+   +    +  I +L  + 
Sbjct: 3844 EPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDY 3903

Query: 398  QRKFNVEKPLIFNTYQCYLKDA--YDNVTLDVE--LARREGWCFGAKLVRGA-------Y 446
            Q   ++ K  +F+  +  +KD   Y++   +VE  L +  G      L+  +        
Sbjct: 3904 QDLCSIGKEHVFSL-EAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETITQQ 3962

Query: 447  LAQERARAAEI-GYEDPINPTYEATNAMYHRCLDYVLEELKHNAKAKVMVASHNEDTVRF 505
            LA  +A   EI G+ED +N      + +  +C D++  +LK N  A +     +   +  
Sbjct: 3963 LAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICS 4022

Query: 506  ALRRMEELGLHPADHRVYFGQLLGMC 531
              +RM +   H     V     L  C
Sbjct: 4023 TAQRMYQSLEHELQKHVSRQDTLQQC 4048


>gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens]
          Length = 1630

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 29/77 (37%), Positives = 35/77 (45%), Gaps = 9/77 (11%)

Query: 5   RALPALRPCIPRFVPLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDFGNAQEAYRS 64
           RA+PA     P   PL  APA + QP  G A+V G  S   +    PA   G A  A  +
Sbjct: 59  RAVPAPSGLPPPPPPLP-APADQTQPPHGEASVAGEESTAGIPEAAPAA--GEASSAAAA 115

Query: 65  RRTWELARSLLVLRLCA 81
                 A  LL+L LCA
Sbjct: 116 ------AAVLLMLDLCA 126


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 15/79 (18%)

Query: 4   RRALPALRPCIPRFVPLSTA-------PASREQPA----AGPAAVPGGGSATAVRPPVPA 52
           R A P   P  PR  P + A       PA    PA    A PA  P   +A A  PP P 
Sbjct: 104 RGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP- 162

Query: 53  VDFGNAQEAYRSRRTWELA 71
              G AQ   R++R   LA
Sbjct: 163 ---GPAQPGPRAQRAAPLA 178


>gi|156105697 ring finger and CCCH-type zinc finger domains 2
           isoform 1 [Homo sapiens]
          Length = 1191

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 14/71 (19%)

Query: 12  PCIPRFVPLSTAPASREQPAAGPAA--------------VPGGGSATAVRPPVPAVDFGN 57
           PC+PRFV  +  P S   PA+ P A               P          PVP V  G 
Sbjct: 631 PCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGM 690

Query: 58  AQEAYRSRRTW 68
               Y SRR W
Sbjct: 691 YAPVYDSRRIW 701


>gi|156105699 ring finger and CCCH-type zinc finger domains 2
           isoform 2 [Homo sapiens]
          Length = 1064

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 23/71 (32%), Positives = 26/71 (36%), Gaps = 14/71 (19%)

Query: 12  PCIPRFVPLSTAPASREQPAAGPAA--------------VPGGGSATAVRPPVPAVDFGN 57
           PC+PRFV  +  P S   PA+ P A               P          PVP V  G 
Sbjct: 631 PCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGM 690

Query: 58  AQEAYRSRRTW 68
               Y SRR W
Sbjct: 691 YAPVYDSRRIW 701


>gi|4502739 cyclin-dependent kinase 5, regulatory subunit 2 [Homo
           sapiens]
          Length = 367

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 28/79 (35%), Positives = 33/79 (41%), Gaps = 13/79 (16%)

Query: 15  PRFVPLSTAPASR---EQPAAGPAAV--PGGGSATAVRPPVPA------VDFGNAQEAYR 63
           P  VP+ T PA+    E P+ G AA   PG G      PP PA      V  G+ +    
Sbjct: 120 PLAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIV 179

Query: 64  SRRTWELARSL--LVLRLC 80
              T EL R L   V R C
Sbjct: 180 QASTGELLRCLGDFVCRRC 198


>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
          Length = 525

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 14/29 (48%), Positives = 17/29 (58%)

Query: 542 GYPVYKYVPYGPVMEVLPYLSRRALENSS 570
           G+P  KY P GP  +V+ Y S R LE  S
Sbjct: 460 GFPTLKYFPAGPGRKVIEYKSTRDLETFS 488


>gi|41406086 semaphorin 3D [Homo sapiens]
          Length = 777

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 4/95 (4%)

Query: 418 DAYDNVTLDVELARREGWCF--GAKLVRGAYLAQERARAAEIGYEDPINPTYEATNAMYH 475
           D Y     D  LAR + +C   G    R A  ++ RAR  ++ Y DPI   ++  +++ H
Sbjct: 535 DTYGKACADCCLAR-DPYCAWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISH 593

Query: 476 RCLD-YVLEELKHNAKAKVMVASHNEDTVRFALRR 509
              D  V+  ++ N+     +    + T+++ ++R
Sbjct: 594 ETADEKVIFGIEFNSTFLECIPKSQQATIKWYIQR 628


>gi|189027129 phosphodiesterase 12 [Homo sapiens]
          Length = 609

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 5/57 (8%)

Query: 465 PTYEATNAMYHRCLDYVLEELKH-NAKAKVMVASHNEDTVRFALRRMEELGLHPADH 520
           P Y      +H CLDY+  +L     +  + + SH E T   AL  +     HP+DH
Sbjct: 547 PAYTNYVGGFHGCLDYIFIDLNALEVEQVIPLPSHEEVTTHQALPSVS----HPSDH 599


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 2/45 (4%)

Query: 19  PLSTAPASREQPAAGPAAVPG--GGSATAVRPPVPAVDFGNAQEA 61
           P    PAS   PA+GP A PG   G   A   P PA+  G++  A
Sbjct: 87  PPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAA 131


>gi|74271816 radical fringe [Homo sapiens]
          Length = 331

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 20/48 (41%), Positives = 26/48 (54%), Gaps = 3/48 (6%)

Query: 1  MALRRALPALRPCIPRFVPLSTAPASREQPAAGPAAVPGGGSATAVRP 48
          +AL  AL AL   +P  +PL  APA    PA  P A P   +A ++RP
Sbjct: 13 LALAAALAALL-LLP--LPLPRAPAPARTPAPAPRAPPSRPAAPSLRP 57


>gi|40548415 dishevelled associated activator of morphogenesis 2
           [Homo sapiens]
          Length = 1067

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 15/53 (28%), Positives = 23/53 (43%)

Query: 3   LRRALPALRPCIPRFVPLSTAPASREQPAAGPAAVPGGGSATAVRPPVPAVDF 55
           LR+A   +   + +   LST P S   P  GP  +    +   + PP P + F
Sbjct: 497 LRQARGQVAELVAQLSELSTGPVSSPPPPGGPLTLSSSMTTNDLPPPPPPLPF 549


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,612,523
Number of Sequences: 37866
Number of extensions: 942757
Number of successful extensions: 3939
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3917
Number of HSP's gapped (non-prelim): 23
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.