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Search of human proteins with 18254478
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
(217 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 436 e-122
gi|214832050 dual specificity phosphatase 19 isoform 2 [Homo sap... 310 5e-85
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 106 2e-23
gi|239582767 slingshot homolog 3 [Homo sapiens] 102 2e-22
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 99 2e-21
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 96 3e-20
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 95 5e-20
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 94 7e-20
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 93 2e-19
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 93 2e-19
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 93 2e-19
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 93 2e-19
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 92 4e-19
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 91 1e-18
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 91 1e-18
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 91 1e-18
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 91 1e-18
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 91 1e-18
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 91 1e-18
gi|37674210 slingshot 2 [Homo sapiens] 90 2e-18
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 88 5e-18
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 87 8e-18
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 87 8e-18
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 84 7e-17
gi|6005956 dual specificity phosphatase 12 [Homo sapiens] 84 7e-17
gi|4758208 dual specificity phosphatase 3 [Homo sapiens] 84 9e-17
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 83 2e-16
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 81 6e-16
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 81 6e-16
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 80 2e-15
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 436 bits (1120), Expect = e-122
Identities = 217/217 (100%), Positives = 217/217 (100%)
Query: 1 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL 60
MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL
Sbjct: 1 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL 60
Query: 61 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDL 120
SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDL
Sbjct: 61 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDL 120
Query: 121 PETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV 180
PETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV
Sbjct: 121 PETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV 180
Query: 181 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS 217
KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
Sbjct: 181 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS 217
>gi|214832050 dual specificity phosphatase 19 isoform 2 [Homo
sapiens]
Length = 166
Score = 310 bits (795), Expect = 5e-85
Identities = 166/217 (76%), Positives = 166/217 (76%), Gaps = 51/217 (23%)
Query: 1 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL 60
MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL
Sbjct: 1 MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDL 60
Query: 61 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDL 120
SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNK
Sbjct: 61 SSDLQVGVIKPWLLLGSQDAAHDLDTLKKNK----------------------------- 91
Query: 121 PETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV 180
DGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV
Sbjct: 92 ----------------------DGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLV 129
Query: 181 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS 217
KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS
Sbjct: 130 KNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS 166
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 106 bits (264), Expect = 2e-23
Identities = 59/149 (39%), Positives = 83/149 (55%), Gaps = 8/149 (5%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVA-----YGVENAFLSDFTYKSISILDLPET 123
I P+L LG++ A DLDT+++ + +++NV Y E F YK + D +
Sbjct: 325 ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGL---FNYKRLPATDSNKQ 381
Query: 124 NILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNA 183
N+ YF E FEFIEEA + +L+HC AGVSR+A IVI +LM + + T A+ VK
Sbjct: 382 NLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGK 441
Query: 184 RPSICPNSGFMEQLRTYQEGKESNKCDRI 212
RP I PN FM QL ++E + RI
Sbjct: 442 RPIISPNLNFMGQLLEFEEDLNNGVTPRI 470
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 102 bits (254), Expect = 2e-22
Identities = 54/133 (40%), Positives = 79/133 (59%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
I P L LGS+ A +L+ L++N+VTHILN+A ++N + FTY ++ + D +L +
Sbjct: 332 IFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPH 391
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
+ E FIE A+ + VLVHC GVSR+AA V+ + M + S A V+ RP
Sbjct: 392 WKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIAR 451
Query: 189 PNSGFMEQLRTYQ 201
PN GF+ QL+ YQ
Sbjct: 452 PNPGFLRQLQIYQ 464
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 99.4 bits (246), Expect = 2e-21
Identities = 57/145 (39%), Positives = 79/145 (54%), Gaps = 3/145 (2%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFL--SDFTYKSISILDLPETNIL 126
I P+L LG + +LD L K + +ILNV + NAF +FTYK I I D N+
Sbjct: 248 ILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLS 307
Query: 127 SYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS 186
+FPE FI+EA+ K VLVHC AG+SR+ + + +LM S A+ VK + +
Sbjct: 308 QFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSN 367
Query: 187 ICPNSGFMEQLRTYQEGKE-SNKCD 210
I PN FM QL ++ S+ CD
Sbjct: 368 ISPNFNFMGQLLDFERTLGLSSPCD 392
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 95.5 bits (236), Expect = 3e-20
Identities = 54/133 (40%), Positives = 71/133 (53%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
I P+L LGS + DL L+ +T +LNV+ N F F YKSI + D I ++
Sbjct: 176 ILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAW 235
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
F E FI+ K G VLVHC AG+SR+A I + +LM S + AF VK R I
Sbjct: 236 FQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVIS 295
Query: 189 PNSGFMEQLRTYQ 201
PN FM QL ++
Sbjct: 296 PNFSFMGQLLQFE 308
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 94.7 bits (234), Expect = 5e-20
Identities = 54/145 (37%), Positives = 80/145 (55%), Gaps = 3/145 (2%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAF--LSDFTYKSISILDLPETNIL 126
I P+L LG + +LD L++ + +ILNV + N F +F YK I I D N+
Sbjct: 210 ILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLS 269
Query: 127 SYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS 186
+FPE FI+EA+ K+ VLVHC AG+SR+ + + +LM S A+ +VK + +
Sbjct: 270 QFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSN 329
Query: 187 ICPNSGFMEQLRTYQEGKE-SNKCD 210
I PN FM QL ++ S+ CD
Sbjct: 330 ISPNFNFMGQLLDFERTLGLSSPCD 354
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 94.4 bits (233), Expect = 7e-20
Identities = 55/135 (40%), Positives = 76/135 (56%), Gaps = 2/135 (1%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLS--DFTYKSISILDLPETNIL 126
I P L LGS + +L++L K + +ILNV + N F DF YK I I D N+
Sbjct: 207 ILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLS 266
Query: 127 SYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS 186
+FPE EFI+EA ++ VLVHC AGVSR+ + + +LM S A+ LVK + +
Sbjct: 267 RFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSN 326
Query: 187 ICPNSGFMEQLRTYQ 201
I PN FM QL ++
Sbjct: 327 ISPNFNFMGQLLDFE 341
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 93.2 bits (230), Expect = 2e-19
Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 5/150 (3%)
Query: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
L LGS+ A +L+ L+ + V +ILNV ++N F F Y +I + D T++L+++ E
Sbjct: 316 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 375
Query: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
+ FI +AKR LVHC GVSR+A+ VI + M A++ VK R PN+G
Sbjct: 376 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 435
Query: 193 FMEQLRTYQ-----EGKESNKCDRIQENSS 217
FM QL Y+ + NK R Q +SS
Sbjct: 436 FMRQLSEYEGILDASKQRHNKLWRQQTDSS 465
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 93.2 bits (230), Expect = 2e-19
Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 5/150 (3%)
Query: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
L LGS+ A +L+ L+ + V +ILNV ++N F F Y +I + D T++L+++ E
Sbjct: 327 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 386
Query: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
+ FI +AKR LVHC GVSR+A+ VI + M A++ VK R PN+G
Sbjct: 387 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 446
Query: 193 FMEQLRTYQ-----EGKESNKCDRIQENSS 217
FM QL Y+ + NK R Q +SS
Sbjct: 447 FMRQLSEYEGILDASKQRHNKLWRQQTDSS 476
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 93.2 bits (230), Expect = 2e-19
Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 5/150 (3%)
Query: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
L LGS+ A +L+ L+ + V +ILNV ++N F F Y +I + D T++L+++ E
Sbjct: 316 LYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEA 375
Query: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
+ FI +AKR LVHC GVSR+A+ VI + M A++ VK R PN+G
Sbjct: 376 YHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAG 435
Query: 193 FMEQLRTYQ-----EGKESNKCDRIQENSS 217
FM QL Y+ + NK R Q +SS
Sbjct: 436 FMRQLSEYEGILDASKQRHNKLWRQQTDSS 465
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 92.8 bits (229), Expect = 2e-19
Identities = 51/133 (38%), Positives = 71/133 (53%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
I P+L LGS A D L +T ++NV+ N F + YKSI + D + +I S+
Sbjct: 177 ILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSW 236
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
F E +FI+ K G V VHC AG+SR+A I + +LM + + AF VK R I
Sbjct: 237 FNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIIS 296
Query: 189 PNSGFMEQLRTYQ 201
PN FM QL ++
Sbjct: 297 PNFSFMGQLLQFE 309
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 91.7 bits (226), Expect = 4e-19
Identities = 49/132 (37%), Positives = 68/132 (51%), Gaps = 1/132 (0%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
+ P L LG+ A DLD L +NK+THI+++ + L D TY I + D PE I +
Sbjct: 8 VLPGLYLGNFIDAKDLDQLGRNKITHIISI-HESPQPLLQDITYLRIPVADTPEVPIKKH 66
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
F EC FI + G LVHC AG+SR+ IV ++M + +K RP
Sbjct: 67 FKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIAN 126
Query: 189 PNSGFMEQLRTY 200
PN GF +QL +
Sbjct: 127 PNPGFRQQLEEF 138
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 90.5 bits (223), Expect = 1e-18
Identities = 53/140 (37%), Positives = 79/140 (56%), Gaps = 7/140 (5%)
Query: 69 IKPWLLLGSQDAA--HDLDTLKKNKVTHILNVAYGVENAFLSD-----FTYKSISILDLP 121
I P L LG +A L L+K+ +THI+ + +E F+ F Y + I D P
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 122 ETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVK 181
NI+ +FP EFI+ + + G VLVH NAG+SR+AA VI ++M + + AF+ V+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 182 NARPSICPNSGFMEQLRTYQ 201
R I PN+GF+ QL+ Y+
Sbjct: 152 ERRFCINPNAGFVHQLQEYE 171
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 90.5 bits (223), Expect = 1e-18
Identities = 53/140 (37%), Positives = 79/140 (56%), Gaps = 7/140 (5%)
Query: 69 IKPWLLLGSQDAA--HDLDTLKKNKVTHILNVAYGVENAFLSD-----FTYKSISILDLP 121
I P L LG +A L L+K+ +THI+ + +E F+ F Y + I D P
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 122 ETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVK 181
NI+ +FP EFI+ + + G VLVH NAG+SR+AA VI ++M + + AF+ V+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 182 NARPSICPNSGFMEQLRTYQ 201
R I PN+GF+ QL+ Y+
Sbjct: 152 ERRFCINPNAGFVHQLQEYE 171
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 90.5 bits (223), Expect = 1e-18
Identities = 53/140 (37%), Positives = 79/140 (56%), Gaps = 7/140 (5%)
Query: 69 IKPWLLLGSQDAA--HDLDTLKKNKVTHILNVAYGVENAFLSD-----FTYKSISILDLP 121
I P L LG +A L L+K+ +THI+ + +E F+ F Y + I D P
Sbjct: 32 ILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNP 91
Query: 122 ETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVK 181
NI+ +FP EFI+ + + G VLVH NAG+SR+AA VI ++M + + AF+ V+
Sbjct: 92 VENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQ 151
Query: 182 NARPSICPNSGFMEQLRTYQ 201
R I PN+GF+ QL+ Y+
Sbjct: 152 ERRFCINPNAGFVHQLQEYE 171
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 90.5 bits (223), Expect = 1e-18
Identities = 50/133 (37%), Positives = 71/133 (53%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
I P+L LGS A + L +T +LNV+ A + YK I + D +I S+
Sbjct: 182 ILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISSH 241
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
F E +FI+ + K G VLVHC AG+SR+ I + +LM ++Q AF +K R +
Sbjct: 242 FQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVS 301
Query: 189 PNSGFMEQLRTYQ 201
PN GFM QL Y+
Sbjct: 302 PNFGFMGQLLQYE 314
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 90.5 bits (223), Expect = 1e-18
Identities = 53/141 (37%), Positives = 73/141 (51%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
I P+L LGS A D L +T +LNV+ N F + YK I + D + +I S+
Sbjct: 199 ILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSW 258
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
F E E+I+ K G VLVHC AG+SR+A I + +LM ++ AF VK R I
Sbjct: 259 FMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIIS 318
Query: 189 PNSGFMEQLRTYQEGKESNKC 209
PN FM QL ++ + C
Sbjct: 319 PNFSFMGQLLQFESQVLATSC 339
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 90.5 bits (223), Expect = 1e-18
Identities = 53/141 (37%), Positives = 73/141 (51%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
I P+L LGS A D L +T +LNV+ N F + YK I + D + +I S+
Sbjct: 108 ILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSW 167
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
F E E+I+ K G VLVHC AG+SR+A I + +LM ++ AF VK R I
Sbjct: 168 FMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIIS 227
Query: 189 PNSGFMEQLRTYQEGKESNKC 209
PN FM QL ++ + C
Sbjct: 228 PNFSFMGQLLQFESQVLATSC 248
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 89.7 bits (221), Expect = 2e-18
Identities = 48/129 (37%), Positives = 72/129 (55%)
Query: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
+ LGS+ A +L+ L+ V +ILNV ++N F F Y +I + D T++L+Y+ +
Sbjct: 315 VFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDEEATDLLAYWNDT 374
Query: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
++FI +AK+ LVHC GVSR+A+ VI + M + A+ VK R PN
Sbjct: 375 YKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTVTKPNPS 434
Query: 193 FMEQLRTYQ 201
FM QL YQ
Sbjct: 435 FMRQLEEYQ 443
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 88.2 bits (217), Expect = 5e-18
Identities = 45/129 (34%), Positives = 69/129 (53%)
Query: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
L + + AA++ L N++T ++NV+ V N D Y + + D P + + +F
Sbjct: 27 LYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYMQVPVADSPNSRLCDFFDPI 86
Query: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
+ I + K G L+HC AGVSR+AA+ + +LM S A + K+ RP I PNSG
Sbjct: 87 ADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSG 146
Query: 193 FMEQLRTYQ 201
F EQL Y+
Sbjct: 147 FWEQLIHYE 155
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 87.4 bits (215), Expect = 8e-18
Identities = 45/103 (43%), Positives = 59/103 (57%)
Query: 110 FTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSE 169
F YK + D + N+ YF E FEFIEEA + +L+HC AGVSR+A IVI +LM
Sbjct: 26 FNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHT 85
Query: 170 QTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRI 212
+ + T A+ VK RP I PN FM QL ++E + RI
Sbjct: 86 RMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRI 128
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 87.4 bits (215), Expect = 8e-18
Identities = 45/103 (43%), Positives = 59/103 (57%)
Query: 110 FTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSE 169
F YK + D + N+ YF E FEFIEEA + +L+HC AGVSR+A IVI +LM
Sbjct: 26 FNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHT 85
Query: 170 QTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRI 212
+ + T A+ VK RP I PN FM QL ++E + RI
Sbjct: 86 RMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRI 128
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 84.3 bits (207), Expect = 7e-17
Identities = 48/134 (35%), Positives = 68/134 (50%), Gaps = 1/134 (0%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSY 128
I P L +G+ A D + L KNKVTHIL+V + L Y I D P N+ +
Sbjct: 8 ILPGLYIGNFKDARDAEQLSKNKVTHILSV-HDSARPMLEGVKYLCIPAADSPSQNLTRH 66
Query: 129 FPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSIC 188
F E +FI E + + LVHC AGVSR+ +VI ++M + A V+ R
Sbjct: 67 FKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCAN 126
Query: 189 PNSGFMEQLRTYQE 202
PN GF QL+ +++
Sbjct: 127 PNVGFQRQLQEFEK 140
>gi|6005956 dual specificity phosphatase 12 [Homo sapiens]
Length = 340
Score = 84.3 bits (207), Expect = 7e-17
Identities = 54/163 (33%), Positives = 83/163 (50%), Gaps = 10/163 (6%)
Query: 48 PSSGGGCGYVQDLSSDL----QVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVE 103
P GC +S + Q+ ++P L G A + D L++ +T +L V E
Sbjct: 5 PGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVD-SEE 63
Query: 104 NAF-----LSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAA 158
+F + D + LD PET++LS+ C FI +A+ + VLVHC+AGVSR+
Sbjct: 64 PSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVSRSV 123
Query: 159 AIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQ 201
AI+ FLM ++Q F A+ ++ +P N GF QL+ YQ
Sbjct: 124 AIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQ 166
>gi|4758208 dual specificity phosphatase 3 [Homo sapiens]
Length = 185
Score = 84.0 bits (206), Expect = 9e-17
Identities = 61/173 (35%), Positives = 87/173 (50%), Gaps = 24/173 (13%)
Query: 49 SSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFL- 107
S G GC L S + P + +G+ A D+ L+K +TH+LN A G +F+
Sbjct: 17 SDGSGC---YSLPSQ-PCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEG--RSFMH 70
Query: 108 ----------SDFTYKSISILDLPETNILSYFPECFEFIEEA-KRKDGVVLVHCNAGVSR 156
S TY I D E N+ +YF +FI++A +K+G VLVHC G SR
Sbjct: 71 VNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSR 130
Query: 157 AAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQL-----RTYQEGK 204
+ +VI +LM ++ SA S+V+ R I PN GF+ QL R +EGK
Sbjct: 131 SPTLVIAYLMMRQKMDVKSALSIVRQNR-EIGPNDGFLAQLCQLNDRLAKEGK 182
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 83.2 bits (204), Expect = 2e-16
Identities = 43/129 (33%), Positives = 67/129 (51%)
Query: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
L L + AA+D L N++T I+N + V N F Y + + D ++ + +F
Sbjct: 29 LFLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPI 88
Query: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
+ I + G L+HC AGVSR+A++ + +LM S A + K+ RP I PN+G
Sbjct: 89 ADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNG 148
Query: 193 FMEQLRTYQ 201
F EQL Y+
Sbjct: 149 FWEQLINYE 157
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 81.3 bits (199), Expect = 6e-16
Identities = 46/129 (35%), Positives = 61/129 (47%)
Query: 73 LLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPEC 132
L LG A + L+ +T I+N + N F Y + + D+P I YF
Sbjct: 34 LFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTV 93
Query: 133 FEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSG 192
+ I RK G LVHC AGVSR+A + I +LM A++ VK RP I PN G
Sbjct: 94 ADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVG 153
Query: 193 FMEQLRTYQ 201
F QL Y+
Sbjct: 154 FWRQLIDYE 162
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 81.3 bits (199), Expect = 6e-16
Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENA-FLSDFTYKSISILDLPETNILS 127
I P L LGSQ + D + +N ++++LN + F+ + + + I D +L
Sbjct: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLP 223
Query: 128 YFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSI 187
+ + EFI++AK V+VHC AG+SR+A I I ++M + S A+ VK+ RPSI
Sbjct: 224 WLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSI 283
Query: 188 CPNSGFMEQLRTYQ 201
PN F+ QL Y+
Sbjct: 284 SPNFNFLGQLLEYE 297
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 79.7 bits (195), Expect = 2e-15
Identities = 45/135 (33%), Positives = 73/135 (54%), Gaps = 1/135 (0%)
Query: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENA-FLSDFTYKSISILDLPETNILS 127
I P L LG Q + + +++N + ++LN + F+ + + + + D IL
Sbjct: 162 ILPNLYLGCQRDVLNKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILP 221
Query: 128 YFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSI 187
+ + +FIE+AK +G VLVHC AG+SR+A I I ++M S A+ VK RP+I
Sbjct: 222 WLDKSVDFIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRPTI 281
Query: 188 CPNSGFMEQLRTYQE 202
PN F+ QL Y++
Sbjct: 282 SPNFNFLGQLLDYEK 296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,618,128
Number of Sequences: 37866
Number of extensions: 302653
Number of successful extensions: 750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 650
Number of HSP's gapped (non-prelim): 101
length of query: 217
length of database: 18,247,518
effective HSP length: 98
effective length of query: 119
effective length of database: 14,536,650
effective search space: 1729861350
effective search space used: 1729861350
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.