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Search of human proteins with 181337167
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
(771 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|181337167 solute carrier family 7 (cationic amino acid transp... 1535 0.0
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 452 e-127
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 443 e-124
gi|110347453 solute carrier family 7 (cationic amino acid transp... 412 e-115
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 411 e-114
gi|114326550 solute carrier family 7 (cationic amino acid transp... 404 e-112
gi|114326544 solute carrier family 7 (cationic amino acid transp... 404 e-112
gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 86 1e-16
gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 86 1e-16
gi|71979932 solute carrier family 7 (cationic amino acid transpo... 86 1e-16
gi|7657683 solute carrier family 7, (cationic amino acid transpo... 81 4e-15
gi|71999149 solute carrier family 7, (cationic amino acid transp... 79 2e-14
gi|115648063 solute carrier family 7 (cationic amino acid transp... 78 4e-14
gi|115648022 solute carrier family 7 (cationic amino acid transp... 78 4e-14
gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 74 5e-13
gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 74 5e-13
gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 74 5e-13
gi|33286428 solute carrier family 7 (cationic amino acid transpo... 72 1e-12
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 69 2e-11
gi|33286430 solute carrier family 7 (cationic amino acid transpo... 42 0.003
gi|225579067 solute carrier family 12, member 4 isoform e [Homo ... 36 0.12
gi|225579065 solute carrier family 12, member 4 isoform d [Homo ... 36 0.12
gi|225579063 solute carrier family 12, member 4 isoform c [Homo ... 36 0.12
gi|225579061 solute carrier family 12, member 4 isoform b [Homo ... 36 0.12
gi|4827006 solute carrier family 12, member 4 isoform a [Homo sa... 36 0.12
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 36 0.12
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 36 0.12
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 36 0.12
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 36 0.12
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 36 0.12
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 1535 bits (3973), Expect = 0.0
Identities = 771/771 (100%), Positives = 771/771 (100%)
Query: 1 MSGFFTSLDPRRVQWGAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLIS 60
MSGFFTSLDPRRVQWGAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLIS
Sbjct: 1 MSGFFTSLDPRRVQWGAAWYAMHSRILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLIS 60
Query: 61 LGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAY 120
LGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAY
Sbjct: 61 LGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAY 120
Query: 121 TYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGL 180
TYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGL
Sbjct: 121 TYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGL 180
Query: 181 GKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKY 240
GKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKY
Sbjct: 181 GKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKY 240
Query: 241 WAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAY 300
WAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAY
Sbjct: 241 WAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAY 300
Query: 301 VSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRV 360
VSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRV
Sbjct: 301 VSVSVILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRV 360
Query: 361 IYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
IYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT
Sbjct: 361 IYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
Query: 421 LVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNT 480
LVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNT
Sbjct: 421 LVSVCVLLLRYQPESDIDGFVKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNT 480
Query: 481 CGAKNLPSLGDNEMLIGKSDKSTYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPH 540
CGAKNLPSLGDNEMLIGKSDKSTYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPH
Sbjct: 481 CGAKNLPSLGDNEMLIGKSDKSTYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPH 540
Query: 541 YYTMRIRLGLPGKMDRPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILL 600
YYTMRIRLGLPGKMDRPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILL
Sbjct: 541 YYTMRIRLGLPGKMDRPTAATGHTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILL 600
Query: 601 VVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAV 660
VVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAV
Sbjct: 601 VVLMVLLISTLVFVILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAV 660
Query: 661 WCFVGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQEDW 720
WCFVGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQEDW
Sbjct: 661 WCFVGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQEDW 720
Query: 721 GGPTEDKGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE 771
GGPTEDKGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE
Sbjct: 721 GGPTEDKGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE 771
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 452 bits (1162), Expect = e-127
Identities = 273/679 (40%), Positives = 385/679 (56%), Gaps = 117/679 (17%)
Query: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYA 106
TKL + L+T+DLI+LGVGS +G G+YV++G VAK +GP ++VSF+IAA+AS+++G+CYA
Sbjct: 28 TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYA 87
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTI 166
EFG RVPKT GSAY Y+YVTVGE AF GWNLIL Y+IGT++ A A S FD L + I
Sbjct: 88 EFGARVPKT-GSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQI 146
Query: 167 SRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWV 226
+++ + +N G E YPD A+ + +++ +++ GVK S N V +N+ V +
Sbjct: 147 GQFLR-TYFRMNYTGLAE--YPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLL 203
Query: 227 FIMIAGLFFINGKYW--------------------------AEGQFLPHGWSGVLQGAAT 260
F+M+AG N W G F+P+G++G L GAAT
Sbjct: 204 FVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAAT 263
Query: 261 CFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTES 320
CFYAF+GFD IATTGEE +NP +IP I SL++C AY VS LTLM+PYY +D +S
Sbjct: 264 CFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKS 323
Query: 321 PLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSY 380
PL F G+ AK+VVA GS+ L+ SLLGS+FPMPRVIYAMA DGLLF+ LA ++S
Sbjct: 324 PLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQINSK 383
Query: 381 TETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGF 440
T+TP++A + SG +AAL+A L L+ L++MMSIGTL+AY+LV+ CVL+LRYQP D
Sbjct: 384 TKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLSYD-- 441
Query: 441 VKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGDNEMLIGKSD 500
+ CSP +G LG + + KS+
Sbjct: 442 --------------------QPKCSPEKDG------------------LGSSPRVTSKSE 463
Query: 501 KSTYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMDRPTAA 560
+ + + ++ L+ L+G + + LGL T
Sbjct: 464 SQVTMLQRQGFSMRTLFCPSLLPTQQSASLVSF--LVG---FLAFLVLGL----SVLTTY 514
Query: 561 TGHTVT------ICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFV 614
H +T + +L LF+++F+ AI+L
Sbjct: 515 GVHAITRLEAWSLALLALFLVLFV------------------AIVL-------------T 543
Query: 615 ILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGI 674
I + P+N +K+ +M P LPF+PAF++LVNIYLM++LS TW+RF++W +G LIYF YGI
Sbjct: 544 IWRLPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMAIGFLIYFSYGI 603
Query: 675 WNSTLEISAREEALHQSTY 693
+S LE R+E + Y
Sbjct: 604 RHS-LEGHLRDENNEEDAY 621
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 443 bits (1140), Expect = e-124
Identities = 269/679 (39%), Positives = 383/679 (56%), Gaps = 118/679 (17%)
Query: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYA 106
TKL + L+T+DLI+LGVGS +G G+YV++G VAK +GP ++VSF+IAA+AS+++G+CYA
Sbjct: 68 TKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYA 127
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTI 166
EFG RVPKT GSAY Y+YVTVGE AF GWNLIL Y+IGT++ A A S FD L + I
Sbjct: 128 EFGARVPKT-GSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQI 186
Query: 167 SRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWV 226
+++ + +N G E YPD A+ + +++ +++ GVK S N V +N+ V +
Sbjct: 187 GQFLR-TYFRMNYTGLAE--YPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLL 243
Query: 227 FIMIAGLFFINGKYW--------------------------AEGQFLPHGWSGVLQGAAT 260
F+M+AG N W G F+P+G++G L GAAT
Sbjct: 244 FVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAAT 303
Query: 261 CFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTES 320
CFYAF+GFD IATTGEE +NP +IP I SL++C AY VS LTLM+PYY +D +S
Sbjct: 304 CFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLDEKS 363
Query: 321 PLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSY 380
PL F G+ AK+VVA GS+ L+ SLLGS+FP+PR+++AMA DGLLFRFLA VS
Sbjct: 364 PLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSK- 422
Query: 381 TETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGF 440
++PV A + +G ++AL+A L L+ L++MMSIGTL+AY+LV+ CVL+LRYQP D
Sbjct: 423 RQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLILRYQPGLSYD-- 480
Query: 441 VKFLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGDNEMLIGKSD 500
+ CSP +G LG + + KS+
Sbjct: 481 --------------------QPKCSPEKDG------------------LGSSPRVTSKSE 502
Query: 501 KSTYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMDRPTAA 560
+ + + ++ L+ L+G + + LGL T
Sbjct: 503 SQVTMLQRQGFSMRTLFCPSLLPTQQSASLVSF--LVG---FLAFLVLGL----SVLTTY 553
Query: 561 TGHTVT------ICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFV 614
H +T + +L LF+++F+ AI+L
Sbjct: 554 GVHAITRLEAWSLALLALFLVLFV------------------AIVL-------------T 582
Query: 615 ILQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGI 674
I + P+N +K+ +M P LPF+PAF++LVNIYLM++LS TW+RF++W +G LIYF YGI
Sbjct: 583 IWRLPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWVRFSIWMAIGFLIYFSYGI 642
Query: 675 WNSTLEISAREEALHQSTY 693
+S LE R+E + Y
Sbjct: 643 RHS-LEGHLRDENNEEDAY 660
>gi|110347453 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 4 [Homo sapiens]
Length = 635
Score = 412 bits (1060), Expect = e-115
Identities = 245/655 (37%), Positives = 363/655 (55%), Gaps = 83/655 (12%)
Query: 25 RILRTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAG 84
++ R KP+E + T L + L+T+DL LGVG VG+G+YV++G VAKE+AG
Sbjct: 17 KLNRLKPLED--------STMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAG 68
Query: 85 PGVIVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYL 144
P V++SF +AAVAS+L+ +CYAEFG RVP+T GSAY ++YV++GE AF IGWN++LEY+
Sbjct: 69 PAVLLSFGVAAVASLLAALCYAEFGARVPRT-GSAYLFTYVSMGELWAFLIGWNVLLEYI 127
Query: 145 IGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVA 204
IG AA A A S DS+ +H+I + VG+ G YPD LA I ++ + V+
Sbjct: 128 IGGAAVARAWSGYLDSMFSHSIRNFTETHVGSWQVPLLGH--YPDFLAAGIILLASAFVS 185
Query: 205 LGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWA--EGQFLPHGWSGVLQGAATCF 262
G + S N+ + ++L V +FI+I G W+ EG F P G+SGV+ G A+CF
Sbjct: 186 CGARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAPFGFSGVMAGTASCF 245
Query: 263 YAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPL 322
YAF+GFD+IA + EEA+NP S+P AI SL I AY+ VS +LTLMVP++++D +S L
Sbjct: 246 YAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSAL 305
Query: 323 MEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTE 382
+ F G+ A F+VA GS+ + LL LF +PR++YAMA DGL F+ AHV T+
Sbjct: 306 ADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQ 365
Query: 383 TPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVK 442
PV + G L A LALL+ L L++ +S+GTLLAYT V+ +++LR+Q S
Sbjct: 366 VPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSS------- 418
Query: 443 FLSEEHTKKKEGILADCEKEACSPVSEGDEFSGPATNTCGAKNLPSLGDNEMLIGKSDKS 502
P S G GP T K S D+ L+G
Sbjct: 419 ----------------------PPSSPGPASPGPLT-----KQQSSFSDHLQLVG----- 446
Query: 503 TYNVNHPNYGTVDMTTGIEADESENIYLIKLKKLIGPHYYTMRIRLGLPGKMDRPTAATG 562
T + + P G +LK + P+ G +D + G
Sbjct: 447 TVHASVPEPG-------------------ELKPALRPYL----------GFLD--GYSPG 475
Query: 563 HTVTICVLLLFILMFIFCSFIIFGSDYISEQSWWAILLVVLMVLLISTLVFVILQQPENP 622
VT + ++ ++FG+ + W ILL++L ++ + V+ +
Sbjct: 476 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 535
Query: 623 KKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIWNS 677
++ + P +P +PA ++++NI LMLKLS +TW+RF++W +GL +YFGYGI +S
Sbjct: 536 REDLFQIPMVPLIPALSIVLNICLMLKLSYLTWVRFSIWLLMGLAVYFGYGIRHS 590
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 411 bits (1057), Expect = e-114
Identities = 216/413 (52%), Positives = 286/413 (69%), Gaps = 28/413 (6%)
Query: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYA 106
T+L++ L T DL++LGVGS +G G+YV++G VA+E AGP +++SF+IAA+AS+L+G+CY
Sbjct: 26 TRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYG 85
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTI 166
EFG RVPKT GSAY YSYVTVGE AF GWNLIL Y+IGT++ A A S+ FD L I
Sbjct: 86 EFGARVPKT-GSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRPI 144
Query: 167 SRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWV 226
+ + TLN G E+ PD+ A++I +I+T ++ LGVK S N + +N+ V
Sbjct: 145 GEFSRTHM-TLNAPGVLAEN-PDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLG 202
Query: 227 FIMIAGLFFINGKYW-------------------------AEGQFLPHGWSGVLQGAATC 261
FIM++G + K W G F+P G+SGVL GAATC
Sbjct: 203 FIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATC 262
Query: 262 FYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESP 321
FYAF+GFD IATTGEE KNP +IP I ASL+IC AY VS LTLM+PY+ +D SP
Sbjct: 263 FYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNSP 322
Query: 322 LMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYT 381
L + F G+ AK+ VA+GS+ L+ SLLGS+FPMPRVIYAMA DGLLF+FLA+V+ T
Sbjct: 323 LPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRT 382
Query: 382 ETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPE 434
+TP++A + SG +AA++A L L+DL+++MSIGTLLAY+LV+ CVL+LRYQPE
Sbjct: 383 KTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQPE 435
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 404 bits (1038), Expect = e-112
Identities = 217/438 (49%), Positives = 293/438 (66%), Gaps = 31/438 (7%)
Query: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYA 106
T+LA+ L+T+DL++LGVGS +G G+YV++G VAK+ AGP +++ F++AA++S+L+G+CYA
Sbjct: 26 TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYA 85
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTI 166
EFG RVP++ GSAY YSYVTVGE AF GWNLIL Y+IGTA+ A A SS FD+L + I
Sbjct: 86 EFGARVPRS-GSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHI 144
Query: 167 SRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWV 226
S+ + S+ E YPD AL + +++T ++ALG S V +NL V
Sbjct: 145 SKTLQGSIALHVPHVLAE--YPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLG 202
Query: 227 FIMIAGLFFINGKYW-----------------------AEGQFLPHGWSGVLQGAATCFY 263
F+MI+G + W G F+P G+ G+L+GAATCFY
Sbjct: 203 FVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFY 262
Query: 264 AFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLM 323
AF+GFD IATTGEEA+NP SIP I SL +C AY +VS LTLM+PYY + ESPL
Sbjct: 263 AFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLP 322
Query: 324 EMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTET 383
E F+ G+ A++VVA+GS+ L+ SLLGS+FPMPRVIYAMA DGLLFR LA + + T T
Sbjct: 323 EAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRT 382
Query: 384 PVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKF 443
P++A +VSG +AA +A L L DL+++MSIGTLLAY+LVS+CVL+LRYQP+ +
Sbjct: 383 PIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETK----- 437
Query: 444 LSEEHTKKKEGILADCEK 461
EE ++E I + EK
Sbjct: 438 TGEEVELQEEAITTESEK 455
Score = 97.1 bits (240), Expect = 6e-20
Identities = 52/144 (36%), Positives = 84/144 (58%), Gaps = 3/144 (2%)
Query: 557 PTAATGHTVTICVLLLFILMFIFCSFIIFGS-DYISEQSWWAILLVVLMVLLISTLVFVI 615
PT +G V +C LL +L+ C + S +S W ++V+L++L+I +V VI
Sbjct: 469 PTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIV-VI 527
Query: 616 LQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIW 675
+QP++ L + P LP +P ++ VNIYLM++++ TW RF VW +G IYFGYGI
Sbjct: 528 WRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQ 587
Query: 676 NSTLEISAREEALHQSTYQRYDVD 699
+S EI + + + +S + D+D
Sbjct: 588 HSLEEIKSNQPS-RKSRAKTVDLD 610
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 404 bits (1038), Expect = e-112
Identities = 217/438 (49%), Positives = 293/438 (66%), Gaps = 31/438 (7%)
Query: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGVIVSFIIAAVASILSGVCYA 106
T+LA+ L+T+DL++LGVGS +G G+YV++G VAK+ AGP +++ F++AA++S+L+G+CYA
Sbjct: 26 TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYA 85
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTI 166
EFG RVP++ GSAY YSYVTVGE AF GWNLIL Y+IGTA+ A A SS FD+L + I
Sbjct: 86 EFGARVPRS-GSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHI 144
Query: 167 SRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWV 226
S+ + S+ E YPD AL + +++T ++ALG S V +NL V
Sbjct: 145 SKTLQGSIALHVPHVLAE--YPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLG 202
Query: 227 FIMIAGLFFINGKYW-----------------------AEGQFLPHGWSGVLQGAATCFY 263
F+MI+G + W G F+P G+ G+L+GAATCFY
Sbjct: 203 FVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFY 262
Query: 264 AFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLM 323
AF+GFD IATTGEEA+NP SIP I SL +C AY +VS LTLM+PYY + ESPL
Sbjct: 263 AFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLP 322
Query: 324 EMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTET 383
E F+ G+ A++VVA+GS+ L+ SLLGS+FPMPRVIYAMA DGLLFR LA + + T T
Sbjct: 323 EAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRT 382
Query: 384 PVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKF 443
P++A +VSG +AA +A L L DL+++MSIGTLLAY+LVS+CVL+LRYQP+ +
Sbjct: 383 PIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETK----- 437
Query: 444 LSEEHTKKKEGILADCEK 461
EE ++E I + EK
Sbjct: 438 TGEEVELQEEAITTESEK 455
Score = 97.1 bits (240), Expect = 6e-20
Identities = 52/144 (36%), Positives = 84/144 (58%), Gaps = 3/144 (2%)
Query: 557 PTAATGHTVTICVLLLFILMFIFCSFIIFGS-DYISEQSWWAILLVVLMVLLISTLVFVI 615
PT +G V +C LL +L+ C + S +S W ++V+L++L+I +V VI
Sbjct: 469 PTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIV-VI 527
Query: 616 LQQPENPKKLPYMAPCLPFVPAFAMLVNIYLMLKLSTITWIRFAVWCFVGLLIYFGYGIW 675
+QP++ L + P LP +P ++ VNIYLM++++ TW RF VW +G IYFGYGI
Sbjct: 528 WRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQ 587
Query: 676 NSTLEISAREEALHQSTYQRYDVD 699
+S EI + + + +S + D+D
Sbjct: 588 HSLEEIKSNQPS-RKSRAKTVDLD 610
>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 85.9 bits (211), Expect = 1e-16
Identities = 86/404 (21%), Positives = 169/404 (41%), Gaps = 48/404 (11%)
Query: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVV--SGLVAKEMAGPGVIVSFIIAAVASILSGVC 104
T L + L + IS+ VG+ +G+G++V S L E GP +I+ + V + L +C
Sbjct: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
Query: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANH 164
+AE G + K+ G Y Y G A+ W ++ ++ + + S + +
Sbjct: 83 FAELGTMITKS-GGEYPYLMEAYGPIPAYLFSWASLI------VIKPTSFAIICLSFSEY 135
Query: 165 TISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAV 224
+ + K + LA + ++ + +L V+ N+ L +
Sbjct: 136 VCAPFYVGC--------KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
Query: 225 WVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGA-------ATCFY----AFIGFDIIAT 273
I+I+GL + A+G + +GA + FY A+ G++ +
Sbjct: 188 VAIIIISGLVLL-----AQGN--TKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
Query: 274 TGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEM------FV 327
EE +NP ++P AI + + Y+ ++V Y+T+ T + L++ F
Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNV------SYFTVMTATELLQSQAVAVTFG 294
Query: 328 AHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVA 387
Y A ++V + + G+ F R+IY +G + + L+++S TP A
Sbjct: 295 DRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPA 354
Query: 388 CIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRY 431
I G +A + + + L+ S L Y L + ++++R+
Sbjct: 355 IIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 85.9 bits (211), Expect = 1e-16
Identities = 86/404 (21%), Positives = 169/404 (41%), Gaps = 48/404 (11%)
Query: 47 TKLAQVLTTVDLISLGVGSCVGTGMYVV--SGLVAKEMAGPGVIVSFIIAAVASILSGVC 104
T L + L + IS+ VG+ +G+G++V S L E GP +I+ + V + L +C
Sbjct: 24 TSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLII-WAACGVLATLGALC 82
Query: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANH 164
+AE G + K+ G Y Y G A+ W ++ ++ + + S + +
Sbjct: 83 FAELGTMITKS-GGEYPYLMEAYGPIPAYLFSWASLI------VIKPTSFAIICLSFSEY 135
Query: 165 TISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAV 224
+ + K + LA + ++ + +L V+ N+ L +
Sbjct: 136 VCAPFYVGC--------KPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTAAKLVI 187
Query: 225 WVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGA-------ATCFY----AFIGFDIIAT 273
I+I+GL + A+G + +GA + FY A+ G++ +
Sbjct: 188 VAIIIISGLVLL-----AQGN--TKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNY 240
Query: 274 TGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEM------FV 327
EE +NP ++P AI + + Y+ ++V Y+T+ T + L++ F
Sbjct: 241 ITEELRNPYRNLPLAIIIGIPLVTACYILMNV------SYFTVMTATELLQSQAVAVTFG 294
Query: 328 AHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVA 387
Y A ++V + + G+ F R+IY +G + + L+++S TP A
Sbjct: 295 DRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPA 354
Query: 388 CIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRY 431
I G +A + + + L+ S L Y L + ++++R+
Sbjct: 355 IIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRF 398
>gi|71979932 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5 [Homo sapiens]
Length = 507
Score = 85.9 bits (211), Expect = 1e-16
Identities = 95/407 (23%), Positives = 164/407 (40%), Gaps = 48/407 (11%)
Query: 46 GTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVC 104
G L + +T ++ +++ VG+ +G+G++V V KE PG+ +V + V SI+ +C
Sbjct: 43 GVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALC 102
Query: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMF 158
YAE G + K +G Y Y G AF W +L +Y++ L +F
Sbjct: 103 YAELGTTISK-SGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLF 161
Query: 159 DSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLN 218
+ E L+A L +++T + VK + +
Sbjct: 162 PTC--------------------PVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFA 201
Query: 219 VLNLAVWVFIMIAGLFFI--------NGKYWAEGQFLPHGWSGVLQGAATCFYAFIGFDI 270
L I++ G I + + EG L G ++ + +A+ G++
Sbjct: 202 AAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVG--NIVLALYSGLFAYGGWNY 259
Query: 271 IATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVAHG 330
+ EE NP ++P AI SL I YV LT + + T+ TE L VA
Sbjct: 260 LNFVTEEMINPYRNLPLAIIISLPIVTLVYV-----LTNLAYFTTLSTEQMLSSEAVAVD 314
Query: 331 F---YAAKFVVAIGSVAGLTV--SLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPV 385
F + I GL+ S+ GSLF R+ + + +G L L+ + TPV
Sbjct: 315 FGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPV 374
Query: 386 VACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
+ + + + L A + +I S L L + ++ LR++
Sbjct: 375 PSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRHR 421
>gi|7657683 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 11 [Homo sapiens]
Length = 501
Score = 80.9 bits (198), Expect = 4e-15
Identities = 101/422 (23%), Positives = 173/422 (40%), Gaps = 49/422 (11%)
Query: 32 VESMLEGTGTTTAHGTKLAQVLTTVDL---ISLGVGSCVGTGMYVVSGLVAKEMAGPGVI 88
V L G G + Q+ V L +S+ +G+ +G G+++ V + G+
Sbjct: 20 VNGRLPSLGNKEPPGQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMS 79
Query: 89 VS-FIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGT 147
++ + + V S+ + YAE G + K+ G YTY G AF W +E LI
Sbjct: 80 LTIWTVCGVLSLFGALSYAELGTTIKKS-GGHYTYILEVFGPLPAFVRVW---VELLIIR 135
Query: 148 AAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDL-LALLIAVIVTIIVALG 206
A + +S F R++ + + P+L + L+ AV +T+++ L
Sbjct: 136 PAATAVISLAF--------GRYILEPFFI-------QCEIPELAIKLITAVGITVVMVLN 180
Query: 207 ---VKNSIGFNNVLNVLNLAVWVFIMIAGLF-FINGKYWAEGQFLPHGWSGVLQGAATC- 261
V S L L + I++ G+ I G + Q +SG
Sbjct: 181 SMSVSWSARIQIFLTFCKLTAILIIIVPGVMQLIKG----QTQNFKDAFSGRDSSITRLP 236
Query: 262 ------FYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYT 315
YA+ G+ + EE +NP +IP AI S+ I V++ +LT + + T
Sbjct: 237 LAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLAICISMAI-----VTIGYVLTNVAYFTT 291
Query: 316 IDTESPLMEMFVAHGF---YAAKFVVAIGSVAGLTV--SLLGSLFPMPRVIYAMAGDGLL 370
I+ E L+ VA F F +A+ L+ S+ G +F + R+ Y + +G L
Sbjct: 292 INAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFGSMNGGVFAVSRLFYVASREGHL 351
Query: 371 FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLR 430
L+ + TP+ A IV L ++ L L+ +S L L ++ LR
Sbjct: 352 PEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLLNFLSFARWLFIGLAVAGLIYLR 411
Query: 431 YQ 432
Y+
Sbjct: 412 YK 413
>gi|71999149 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 13 [Homo sapiens]
Length = 470
Score = 78.6 bits (192), Expect = 2e-14
Identities = 99/397 (24%), Positives = 171/397 (43%), Gaps = 44/397 (11%)
Query: 67 VGTGMYVV-SGLVAKEMAGPGV-IVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSY 124
+G G++V G++A GV + + A+ ++ S +C AE + P +G+ Y +
Sbjct: 27 IGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSAEISISFP-CSGAQYYFLK 85
Query: 125 VTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGE 184
G VAF W + G AG + L LA ++I +
Sbjct: 86 RYFGSTVAFLNLWTSLF-LGSGVVAGQALL------LAEYSIQPFFPSC----------- 127
Query: 185 ESYPDL----LALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAVWVFIMIAGL-FFINGK 239
S P L LAL + IV I+ + GVK +VL +++ FI + G+ F I GK
Sbjct: 128 -SVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGK 186
Query: 240 ----------YWAEGQFLPHGWSGVLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAI 289
+ AE + H + QG ++A+ G E K P T+IP I
Sbjct: 187 KENVERFQNAFDAELPDISHLIQAIFQG----YFAYSGGACFTLIAGELKKPRTTIPKCI 242
Query: 290 TASLVICLTAYVSVSV-ILTLMVPYYTIDTESPLMEMFVAHGFYAAKFVVAIGSVAGLTV 348
+L + Y+ V++ LT++ P + +++ + + F + +++ L
Sbjct: 243 FTALPLVTVVYLLVNISYLTVLTPREILSSDAVAI-TWADRAFPSLAWIMPFAISTSLFS 301
Query: 349 SLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLI 408
+LL S+F R IY + +G L ++S++ +P A ++ L +L +L SL DLI
Sbjct: 302 NLLISIFKSSRPIYLASQEGQLPLLFNTLNSHS-SPFTAVLLLVTLGSLAIILTSLIDLI 360
Query: 409 EMMSIGTLLAYTLVSVCVLLLRYQPESDIDGFVKFLS 445
+ L L+ + +L RYQ + + FLS
Sbjct: 361 NYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLS 397
>gi|115648063 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 77.8 bits (190), Expect = 4e-14
Identities = 86/415 (20%), Positives = 167/415 (40%), Gaps = 38/415 (9%)
Query: 32 VESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVS 90
VE + ++ +L + ++ ++ +SL VG+ +G+G++V V A G+ ++
Sbjct: 24 VEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV 83
Query: 91 FIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAG 150
+ I + S++ +CYAE G + K+ G++Y Y G F+AF W + L+ G
Sbjct: 84 WAIGGLFSVVGALCYAELGTTITKS-GASYAYILEAFGGFIAFIRLW---VSLLVVEPTG 139
Query: 151 ASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPD---------LLALLIAVIVTI 201
+ ++ F AN+ I + S+P LLA ++T
Sbjct: 140 QAIIAITF---ANYII-----------------QPSFPSCDPPYLACRLLAAACICLLTF 179
Query: 202 IVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATC 261
+ VK + + + I++ GL + + Q G S + +
Sbjct: 180 VNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLA 239
Query: 262 FYA----FIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTID 317
Y+ + G+D + EE KNP ++P AI S+ I Y+ +V ++ +
Sbjct: 240 LYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVL 299
Query: 318 TESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHV 377
+ + F F + + I L S+F R+ + + +G L L+ +
Sbjct: 300 SSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMI 359
Query: 378 SSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
TP+ A + + +A + ++ + LI S L V L LR++
Sbjct: 360 HIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
>gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 77.8 bits (190), Expect = 4e-14
Identities = 86/415 (20%), Positives = 167/415 (40%), Gaps = 38/415 (9%)
Query: 32 VESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVS 90
VE + ++ +L + ++ ++ +SL VG+ +G+G++V V A G+ ++
Sbjct: 24 VEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV 83
Query: 91 FIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAG 150
+ I + S++ +CYAE G + K+ G++Y Y G F+AF W + L+ G
Sbjct: 84 WAIGGLFSVVGALCYAELGTTITKS-GASYAYILEAFGGFIAFIRLW---VSLLVVEPTG 139
Query: 151 ASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPD---------LLALLIAVIVTI 201
+ ++ F AN+ I + S+P LLA ++T
Sbjct: 140 QAIIAITF---ANYII-----------------QPSFPSCDPPYLACRLLAAACICLLTF 179
Query: 202 IVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATC 261
+ VK + + + I++ GL + + Q G S + +
Sbjct: 180 VNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLA 239
Query: 262 FYA----FIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTID 317
Y+ + G+D + EE KNP ++P AI S+ I Y+ +V ++ +
Sbjct: 240 LYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVL 299
Query: 318 TESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHV 377
+ + F F + + I L S+F R+ + + +G L L+ +
Sbjct: 300 SSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMI 359
Query: 378 SSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
TP+ A + + +A + ++ + LI S L V L LR++
Sbjct: 360 HIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 73.9 bits (180), Expect = 5e-13
Identities = 97/413 (23%), Positives = 167/413 (40%), Gaps = 66/413 (15%)
Query: 48 KLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVCYA 106
KL + ++ ++ + L VG+ +G+G++V V A G+ +V + + + S+ +CYA
Sbjct: 32 KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA 91
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMFDS 160
E G + K+ G++Y Y G F+AF W +L + +I + +F S
Sbjct: 92 ELGTTIKKS-GASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPS 150
Query: 161 -LANHTISRWMADSVGTL-----------NGLGKGEESYPDLLALLIAVIVTIIVALGVK 208
A + SR +A + L L + +Y +LAL IAVIV IV LG
Sbjct: 151 CFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLAL-IAVIVAGIVRLGQG 209
Query: 209 NSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATCFYAFIGF 268
S F N + AV + + +++ G+
Sbjct: 210 ASTHFENSFEGSSFAV---------------------------GDIALALYSALFSYSGW 242
Query: 269 DIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVA 328
D + EE KNP ++P +I S+ I V++ ILT + Y +D L VA
Sbjct: 243 DTLNYVTEEIKNPERNLPLSIGISMPI-----VTIIYILTNVAYYTVLDMRDILASDAVA 297
Query: 329 HGF---------YAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSS 379
F + VA+ GL S++ + R+ + + +G L + +
Sbjct: 298 VTFADQIFGIFNWIIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLPDAICMIHV 353
Query: 380 YTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
TPV + + +G +A + + + LI S L V L LR++
Sbjct: 354 ERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406
>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 73.9 bits (180), Expect = 5e-13
Identities = 97/413 (23%), Positives = 167/413 (40%), Gaps = 66/413 (15%)
Query: 48 KLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVCYA 106
KL + ++ ++ + L VG+ +G+G++V V A G+ +V + + + S+ +CYA
Sbjct: 32 KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA 91
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMFDS 160
E G + K+ G++Y Y G F+AF W +L + +I + +F S
Sbjct: 92 ELGTTIKKS-GASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPS 150
Query: 161 -LANHTISRWMADSVGTL-----------NGLGKGEESYPDLLALLIAVIVTIIVALGVK 208
A + SR +A + L L + +Y +LAL IAVIV IV LG
Sbjct: 151 CFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLAL-IAVIVAGIVRLGQG 209
Query: 209 NSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATCFYAFIGF 268
S F N + AV + + +++ G+
Sbjct: 210 ASTHFENSFEGSSFAV---------------------------GDIALALYSALFSYSGW 242
Query: 269 DIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVA 328
D + EE KNP ++P +I S+ I V++ ILT + Y +D L VA
Sbjct: 243 DTLNYVTEEIKNPERNLPLSIGISMPI-----VTIIYILTNVAYYTVLDMRDILASDAVA 297
Query: 329 HGF---------YAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSS 379
F + VA+ GL S++ + R+ + + +G L + +
Sbjct: 298 VTFADQIFGIFNWIIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLPDAICMIHV 353
Query: 380 YTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
TPV + + +G +A + + + LI S L V L LR++
Sbjct: 354 ERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406
>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 73.9 bits (180), Expect = 5e-13
Identities = 97/413 (23%), Positives = 167/413 (40%), Gaps = 66/413 (15%)
Query: 48 KLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVCYA 106
KL + ++ ++ + L VG+ +G+G++V V A G+ +V + + + S+ +CYA
Sbjct: 32 KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVFGALCYA 91
Query: 107 EFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLIL------EYLIGTAAGASALSSMFDS 160
E G + K+ G++Y Y G F+AF W +L + +I + +F S
Sbjct: 92 ELGTTIKKS-GASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPS 150
Query: 161 -LANHTISRWMADSVGTL-----------NGLGKGEESYPDLLALLIAVIVTIIVALGVK 208
A + SR +A + L L + +Y +LAL IAVIV IV LG
Sbjct: 151 CFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLAL-IAVIVAGIVRLGQG 209
Query: 209 NSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATCFYAFIGF 268
S F N + AV + + +++ G+
Sbjct: 210 ASTHFENSFEGSSFAV---------------------------GDIALALYSALFSYSGW 242
Query: 269 DIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTIDTESPLMEMFVA 328
D + EE KNP ++P +I S+ I V++ ILT + Y +D L VA
Sbjct: 243 DTLNYVTEEIKNPERNLPLSIGISMPI-----VTIIYILTNVAYYTVLDMRDILASDAVA 297
Query: 329 HGF---------YAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSS 379
F + VA+ GL S++ + R+ + + +G L + +
Sbjct: 298 VTFADQIFGIFNWIIPLSVALSCFGGLNASIVAA----SRLFFVGSREGHLPDAICMIHV 353
Query: 380 YTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
TPV + + +G +A + + + LI S L V L LR++
Sbjct: 354 ERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWK 406
>gi|33286428 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform a [Homo
sapiens]
Length = 535
Score = 72.4 bits (176), Expect = 1e-12
Identities = 89/403 (22%), Positives = 169/403 (41%), Gaps = 39/403 (9%)
Query: 46 GTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVSFIIAAVASILSGVC 104
G L + + V + VG+ +G+G++V V + G+ ++ +I+ +++ +C
Sbjct: 33 GVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALC 92
Query: 105 YAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAGASALSSMFDSLANH 164
YAE GV +PK +G Y+Y G F W +L + T AL + +N+
Sbjct: 93 YAELGVTIPK-SGGDYSYVKDIFGGLAGFLRLWIAVL-VIYPTNQAVIAL-----TFSNY 145
Query: 165 TISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVALGVKNSIGFNNVLNVLNLAV 224
+ +GL LLA + +++T + V+ + ++ L
Sbjct: 146 VLQPLFPTCFPPESGL--------RLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLA 197
Query: 225 WVFIMIAGLFFI-NGKY-WAEGQFLPHGWS---------GVLQGAATCFYAFIGFDIIAT 273
I+I G+ I G+Y W E + + LQG+ +A+ G++ +
Sbjct: 198 LALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGS----FAYGGWNFLNY 253
Query: 274 TGEEAKNPNTSIPYAITASLVICLTAYVSVSV-ILTLMVPYYTIDTESPLM---EMFVAH 329
EE +P ++P AI S+ + YV +V +T M P + + + + E +
Sbjct: 254 VTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGV 313
Query: 330 GFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHVSSYTETPVVACI 389
+ VA+ + G+ GSLF R+ +A A +G L LA + TP+ A +
Sbjct: 314 MAWIMPISVALSTFGGVN----GSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALL 369
Query: 390 VSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
+ L+ + + LI + L Y + ++LR++
Sbjct: 370 FTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWK 412
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 68.9 bits (167), Expect = 2e-11
Identities = 87/423 (20%), Positives = 176/423 (41%), Gaps = 43/423 (10%)
Query: 28 RTKPVESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV 87
R P S + GT + L + + + ++ +G+ +G+G+++ V + G+
Sbjct: 15 RPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGL 74
Query: 88 -IVSFIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVT--VGEFVAFFIGWNLILEYL 144
+ +++ + L +CYAE GV +PK+ G Y+YVT G F + W+ + L
Sbjct: 75 ALFVWVLGGGVTALGSLCYAELGVAIPKSGGD---YAYVTEIFGGLAGFLLLWSAV---L 128
Query: 145 IGTAAGASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPDLLALLIAVIVTIIVA 204
I + +S F +N+ + + + +L++ +++T + +
Sbjct: 129 IMYPTSLAVISMTF---SNYVLQPVFPNCIPPTTA--------SRVLSMACLMLLTWVNS 177
Query: 205 LGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAE-----------GQFLPHGWSG 253
V+ + ++ L I+ GL I ++ E + H
Sbjct: 178 SSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALA 237
Query: 254 VLQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSV-ILTLMVP 312
LQG+ +AF G++ + EE + ++P AI S+ + Y ++ T M P
Sbjct: 238 FLQGS----FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSP 293
Query: 313 YYTIDTESPLM---EMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGL 369
+ + + + E + + + VA+ + G+ G LF R+ ++ A +G
Sbjct: 294 QELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGIN----GYLFTYSRLCFSGAREGH 349
Query: 370 LFRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLL 429
L LA + TP+ A +V A++ L+ LI +S L Y + + +LLL
Sbjct: 350 LPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLL 409
Query: 430 RYQ 432
R++
Sbjct: 410 RWR 412
>gi|33286430 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform b [Homo
sapiens]
Length = 332
Score = 41.6 bits (96), Expect = 0.003
Identities = 43/182 (23%), Positives = 81/182 (44%), Gaps = 12/182 (6%)
Query: 255 LQGAATCFYAFIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVI-LTLMVPY 313
LQG+ +A+ G++ + EE +P ++P AI S+ + YV +V +T M P
Sbjct: 36 LQGS----FAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQ 91
Query: 314 YTIDTESPLM---EMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLL 370
+ + + + E + + VA+ + G+ GSLF R+ +A A +G L
Sbjct: 92 ELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVN----GSLFTSSRLFFAGAREGHL 147
Query: 371 FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLR 430
LA + TP+ A + + L+ + + LI + L Y + ++LR
Sbjct: 148 PSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLR 207
Query: 431 YQ 432
++
Sbjct: 208 WK 209
>gi|225579067 solute carrier family 12, member 4 isoform e [Homo
sapiens]
Length = 1054
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
V+ AT F +G + TG A ++ SIP +++ Y S V
Sbjct: 381 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 440
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + + + V + + +V+ IGS + L SL PR++
Sbjct: 441 LFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 500
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 501 AIAKDNIIPFLRVFGH-GKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYL 559
Query: 421 LVSV 424
V++
Sbjct: 560 FVNL 563
>gi|225579065 solute carrier family 12, member 4 isoform d [Homo
sapiens]
Length = 1079
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
V+ AT F +G + TG A ++ SIP +++ Y S V
Sbjct: 406 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 465
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + + + V + + +V+ IGS + L SL PR++
Sbjct: 466 LFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 525
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 526 AIAKDNIIPFLRVFGH-GKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYL 584
Query: 421 LVSV 424
V++
Sbjct: 585 FVNL 588
>gi|225579063 solute carrier family 12, member 4 isoform c [Homo
sapiens]
Length = 1087
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
V+ AT F +G + TG A ++ SIP +++ Y S V
Sbjct: 414 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 473
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + + + V + + +V+ IGS + L SL PR++
Sbjct: 474 LFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 533
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 534 AIAKDNIIPFLRVFGH-GKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYL 592
Query: 421 LVSV 424
V++
Sbjct: 593 FVNL 596
>gi|225579061 solute carrier family 12, member 4 isoform b [Homo
sapiens]
Length = 1079
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
V+ AT F +G + TG A ++ SIP +++ Y S V
Sbjct: 412 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 471
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + + + V + + +V+ IGS + L SL PR++
Sbjct: 472 LFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 531
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 532 AIAKDNIIPFLRVFGH-GKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYL 590
Query: 421 LVSV 424
V++
Sbjct: 591 FVNL 594
>gi|4827006 solute carrier family 12, member 4 isoform a [Homo
sapiens]
Length = 1085
Score = 36.2 bits (82), Expect = 0.12
Identities = 40/184 (21%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
V+ AT F +G + TG A ++ SIP +++ Y S V
Sbjct: 412 VVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVV 471
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + + + V + + +V+ IGS + L SL PR++
Sbjct: 472 LFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 531
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 532 AIAKDNIIPFLRVFGH-GKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYL 590
Query: 421 LVSV 424
V++
Sbjct: 591 FVNL 594
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 36.2 bits (82), Expect = 0.12
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
VL T F +G + TG A K+ SIP +++ Y+S V
Sbjct: 462 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVV 521
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + ++ + V + + +V+ IGS + L SL PR++
Sbjct: 522 LFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 581
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H + E P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 582 AIAKDNIIPFLRVFGHSKANGE-PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYL 640
Query: 421 LVSVCVLL 428
V++ L
Sbjct: 641 FVNLACAL 648
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 36.2 bits (82), Expect = 0.12
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
VL T F +G + TG A K+ SIP +++ Y+S V
Sbjct: 468 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVV 527
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + ++ + V + + +V+ IGS + L SL PR++
Sbjct: 528 LFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 587
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H + E P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 588 AIAKDNIIPFLRVFGHSKANGE-PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYL 646
Query: 421 LVSVCVLL 428
V++ L
Sbjct: 647 FVNLACAL 654
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 36.2 bits (82), Expect = 0.12
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
VL T F +G + TG A K+ SIP +++ Y+S V
Sbjct: 418 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVV 477
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + ++ + V + + +V+ IGS + L SL PR++
Sbjct: 478 LFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 537
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H + E P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 538 AIAKDNIIPFLRVFGHSKANGE-PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYL 596
Query: 421 LVSVCVLL 428
V++ L
Sbjct: 597 FVNLACAL 604
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 36.2 bits (82), Expect = 0.12
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
VL T F +G + TG A K+ SIP +++ Y+S V
Sbjct: 418 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVV 477
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + ++ + V + + +V+ IGS + L SL PR++
Sbjct: 478 LFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 537
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H + E P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 538 AIAKDNIIPFLRVFGHSKANGE-PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYL 596
Query: 421 LVSVCVLL 428
V++ L
Sbjct: 597 FVNLACAL 604
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 36.2 bits (82), Expect = 0.12
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 254 VLQGAATCFYAFIGFDIIATTGEEA--------KNPNTSIPYAITASLVICLTAYVSVSV 305
VL T F +G + TG A K+ SIP +++ Y+S V
Sbjct: 426 VLVDITTSFTLLVGIFFPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVV 485
Query: 306 ILTLMVPYYTIDT---ESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIY 362
+ + + ++ + V + + +V+ IGS + L SL PR++
Sbjct: 486 LFGACIEGVVLRDKFGDAVKGNLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQ 545
Query: 363 AMAGDGLL--FRFLAHVSSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYT 420
A+A D ++ R H + E P A +++ +A L L+ SL + ++S+ L+ Y
Sbjct: 546 AIAKDNIIPFLRVFGHSKANGE-PTWALLLTAAIAELGILIASLDLVAPILSMFFLMCYL 604
Query: 421 LVSVCVLL 428
V++ L
Sbjct: 605 FVNLACAL 612
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,038,660
Number of Sequences: 37866
Number of extensions: 1147582
Number of successful extensions: 2926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2824
Number of HSP's gapped (non-prelim): 83
length of query: 771
length of database: 18,247,518
effective HSP length: 110
effective length of query: 661
effective length of database: 14,082,258
effective search space: 9308372538
effective search space used: 9308372538
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.