Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 18104980

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18104980 protein tyrosine phosphatase, non-receptor type 2
isoform 2 [Homo sapiens]
         (387 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18104980 protein tyrosine phosphatase, non-receptor type 2 is...   793   0.0  
gi|4506291 protein tyrosine phosphatase, non-receptor type 2 iso...   780   0.0  
gi|18104982 protein tyrosine phosphatase, non-receptor type 2 [H...   715   0.0  
gi|4506289 protein tyrosine phosphatase, non-receptor type 1 [Ho...   450   e-127
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...   195   5e-50
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...   195   5e-50
gi|223941891 protein tyrosine phosphatase, non-receptor type 3 i...   191   1e-48
gi|223941888 protein tyrosine phosphatase, non-receptor type 3 i...   191   1e-48
gi|223941885 protein tyrosine phosphatase, non-receptor type 3 i...   191   1e-48
gi|223941882 protein tyrosine phosphatase, non-receptor type 3 i...   191   1e-48
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i...   191   1e-48
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i...   191   1e-48
gi|148728162 protein tyrosine phosphatase, receptor type, J isof...   187   1e-47
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ...   187   1e-47
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ...   187   1e-47
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ...   187   1e-47
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ...   187   1e-47
gi|4506301 protein tyrosine phosphatase, non-receptor type 9 [Ho...   187   2e-47
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [...   185   5e-47
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   185   5e-47
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   185   5e-47
gi|157419150 protein tyrosine phosphatase, receptor type, M isof...   183   2e-46
gi|157419152 protein tyrosine phosphatase, receptor type, M isof...   183   2e-46
gi|194097398 protein tyrosine phosphatase, receptor type, G prec...   178   6e-45
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo...   178   8e-45
gi|104487002 protein tyrosine phosphatase, receptor type, D isof...   177   1e-44
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...   177   1e-44
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo...   177   1e-44
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...   177   1e-44
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo...   177   1e-44

>gi|18104980 protein tyrosine phosphatase, non-receptor type 2
           isoform 2 [Homo sapiens]
          Length = 387

 Score =  793 bits (2047), Expect = 0.0
 Identities = 387/387 (100%), Positives = 387/387 (100%)

Query: 1   MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK 60
           MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
Sbjct: 1   MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK 60

Query: 61  LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
           LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
Sbjct: 61  LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120

Query: 121 VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
           VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
Sbjct: 121 VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180

Query: 181 PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
           PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
Sbjct: 181 PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240

Query: 241 DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300
           DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
Sbjct: 241 DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300

Query: 301 FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT 360
           FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
Sbjct: 301 FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT 360

Query: 361 TAQKVQQMKQRLNENERKRKRPRLTDT 387
           TAQKVQQMKQRLNENERKRKRPRLTDT
Sbjct: 361 TAQKVQQMKQRLNENERKRKRPRLTDT 387


>gi|4506291 protein tyrosine phosphatase, non-receptor type 2
           isoform 1 [Homo sapiens]
          Length = 415

 Score =  780 bits (2015), Expect = 0.0
 Identities = 381/381 (100%), Positives = 381/381 (100%)

Query: 1   MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK 60
           MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
Sbjct: 1   MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK 60

Query: 61  LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
           LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
Sbjct: 61  LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120

Query: 121 VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
           VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
Sbjct: 121 VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180

Query: 181 PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
           PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
Sbjct: 181 PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240

Query: 241 DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300
           DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
Sbjct: 241 DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300

Query: 301 FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT 360
           FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
Sbjct: 301 FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT 360

Query: 361 TAQKVQQMKQRLNENERKRKR 381
           TAQKVQQMKQRLNENERKRKR
Sbjct: 361 TAQKVQQMKQRLNENERKRKR 381


>gi|18104982 protein tyrosine phosphatase, non-receptor type 2 [Homo
           sapiens]
          Length = 353

 Score =  715 bits (1845), Expect = 0.0
 Identities = 346/346 (100%), Positives = 346/346 (100%)

Query: 1   MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK 60
           MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
Sbjct: 1   MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK 60

Query: 61  LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
           LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
Sbjct: 61  LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120

Query: 121 VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
           VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
Sbjct: 121 VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180

Query: 181 PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
           PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
Sbjct: 181 PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240

Query: 241 DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300
           DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
Sbjct: 241 DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300

Query: 301 FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSE 346
           FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSE
Sbjct: 301 FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSE 346


>gi|4506289 protein tyrosine phosphatase, non-receptor type 1 [Homo
           sapiens]
          Length = 435

 Score =  450 bits (1158), Expect = e-127
 Identities = 213/320 (66%), Positives = 263/320 (82%), Gaps = 9/320 (2%)

Query: 5   IEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
           +E+EFE++D    W  +Y +IR+E+ D+P RVAK P+N+NRNRYRDVSP+DHSR+KL   
Sbjct: 3   MEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQE 62

Query: 65  ENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCA 124
           +NDYINASL+ +EEAQRSYILTQGPLPNTC HFW MVW+QK++ VVMLNR++EK S+KCA
Sbjct: 63  DNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCA 122

Query: 125 QYWP-TDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDF 183
           QYWP  +++EM+F++T   + L+SED+KSYYTV  L+LEN+ + ETR I HFHYTTWPDF
Sbjct: 123 QYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDF 182

Query: 184 GVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDD-- 241
           GVPESPASFLNFLFKVRESGSL+P+HGP V+HCSAGIGRSGTF L DTCL+LM+K  D  
Sbjct: 183 GVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPS 242

Query: 242 -INIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300
            ++IK+VLL MRK+RMGLIQT DQLRFSY+A+IEGAK I GDSS+Q +WKELS EDL P 
Sbjct: 243 SVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPP 302

Query: 301 FDH-----SPNKIMTEKYNG 315
            +H      P K + E +NG
Sbjct: 303 PEHIPPPPRPPKRILEPHNG 322


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score =  195 bits (496), Expect = 5e-50
 Identities = 99/258 (38%), Positives = 154/258 (59%), Gaps = 11/258 (4%)

Query: 22   YLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAEND----YINASLVDIE 77
            Y E+++   +    +A  PENR +NRY ++ PYD +RVKL N ++D    YINAS +   
Sbjct: 1925 YEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGN 1984

Query: 78   EAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFK 137
              +R YI+TQGPLP T   FW MVW+Q    +VM+ + VEK  VKC  YWP D   + + 
Sbjct: 1985 NFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYG 2044

Query: 138  ETGFSVKLLSEDVKSYYTVHLLQL---ENINSGETRTISHFHYTTWPDFGVPESPASFLN 194
            +    +++LSE V   +T+   ++   E +++   R I HFHYT WPD GVPE+  S + 
Sbjct: 2045 D--LILQMLSESVLPEWTIREFKICGEEQLDAH--RLIRHFHYTVWPDHGVPETTQSLIQ 2100

Query: 195  FLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKY 254
            F+  VR+  + +P  GP V+HCSAG+GR+GTF  +D  L  ++  D ++I   + ++R +
Sbjct: 2101 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 2160

Query: 255  RMGLIQTPDQLRFSYMAI 272
            R+ ++QT  Q  + +  +
Sbjct: 2161 RVHMVQTECQYVYLHQCV 2178


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score =  195 bits (496), Expect = 5e-50
 Identities = 99/258 (38%), Positives = 154/258 (59%), Gaps = 11/258 (4%)

Query: 22   YLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAEND----YINASLVDIE 77
            Y E+++   +    +A  PENR +NRY ++ PYD +RVKL N ++D    YINAS +   
Sbjct: 1707 YEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGN 1766

Query: 78   EAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFK 137
              +R YI+TQGPLP T   FW MVW+Q    +VM+ + VEK  VKC  YWP D   + + 
Sbjct: 1767 NFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYG 1826

Query: 138  ETGFSVKLLSEDVKSYYTVHLLQL---ENINSGETRTISHFHYTTWPDFGVPESPASFLN 194
            +    +++LSE V   +T+   ++   E +++   R I HFHYT WPD GVPE+  S + 
Sbjct: 1827 D--LILQMLSESVLPEWTIREFKICGEEQLDAH--RLIRHFHYTVWPDHGVPETTQSLIQ 1882

Query: 195  FLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKY 254
            F+  VR+  + +P  GP V+HCSAG+GR+GTF  +D  L  ++  D ++I   + ++R +
Sbjct: 1883 FVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLH 1942

Query: 255  RMGLIQTPDQLRFSYMAI 272
            R+ ++QT  Q  + +  +
Sbjct: 1943 RVHMVQTECQYVYLHQCV 1960


>gi|223941891 protein tyrosine phosphatase, non-receptor type 3
           isoform 6 [Homo sapiens]
          Length = 581

 Score =  191 bits (484), Expect = 1e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 333 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 391

Query: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 392 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 449

Query: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 450 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 506

Query: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 507 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 566

Query: 273 I 273
           +
Sbjct: 567 L 567


>gi|223941888 protein tyrosine phosphatase, non-receptor type 3
           isoform 5 [Homo sapiens]
          Length = 626

 Score =  191 bits (484), Expect = 1e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 378 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 436

Query: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 437 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 494

Query: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 495 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 551

Query: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 552 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 611

Query: 273 I 273
           +
Sbjct: 612 L 612


>gi|223941885 protein tyrosine phosphatase, non-receptor type 3
           isoform 4 [Homo sapiens]
          Length = 737

 Score =  191 bits (484), Expect = 1e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 489 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 547

Query: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 548 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 605

Query: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 606 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 662

Query: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 663 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 722

Query: 273 I 273
           +
Sbjct: 723 L 723


>gi|223941882 protein tyrosine phosphatase, non-receptor type 3
           isoform 3 [Homo sapiens]
          Length = 782

 Score =  191 bits (484), Expect = 1e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 534 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 592

Query: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 593 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 650

Query: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 651 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 707

Query: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 708 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 767

Query: 273 I 273
           +
Sbjct: 768 L 768


>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
           isoform 2 [Homo sapiens]
          Length = 868

 Score =  191 bits (484), Expect = 1e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 620 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 678

Query: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 679 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 736

Query: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 737 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 793

Query: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 794 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 853

Query: 273 I 273
           +
Sbjct: 854 L 854


>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
           isoform 1 [Homo sapiens]
          Length = 913

 Score =  191 bits (484), Expect = 1e-48
 Identities = 101/241 (41%), Positives = 137/241 (56%), Gaps = 10/241 (4%)

Query: 37  AKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIE----EAQRSYILTQGPLPN 92
           AK P+N ++NRY+DV PYD +RV LQ  E DYINAS V++E         YI TQGPLP+
Sbjct: 665 AKLPQNLDKNRYKDVLPYDTTRVLLQGNE-DYINASYVNMEIPAANLVNKYIATQGPLPH 723

Query: 93  TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
           TC  FW +VW QK   +VML  + E+   KC QYWP  D   +    GF ++  SED   
Sbjct: 724 TCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWP--DPPDVMNHGGFHIQCQSEDCTI 781

Query: 153 YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
            Y    + + N  +GE  T++H  Y  WPD GVP+  + FL F+  VR   SL  D  P 
Sbjct: 782 AYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVR---SLRVDSEPV 838

Query: 213 VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
           ++HCSAGIGR+G    ++T + L E+   I    ++  MR  R  ++QT  Q +F   AI
Sbjct: 839 LVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAI 898

Query: 273 I 273
           +
Sbjct: 899 L 899


>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
            precursor [Homo sapiens]
          Length = 1337

 Score =  187 bits (476), Expect = 1e-47
 Identities = 98/296 (33%), Positives = 165/296 (55%), Gaps = 9/296 (3%)

Query: 10   EELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQ---NAEN 66
            ++ D+   +   Y +++      P   A+  ENR +NRY +V PYD SRVKL    ++ +
Sbjct: 1033 QQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNNVLPYDISRVKLSVQTHSTD 1092

Query: 67   DYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQY 126
            DYINA+ +    +++ +I TQGPLPNT   FW MVW++   A++ML + VE+   KC +Y
Sbjct: 1093 DYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEY 1152

Query: 127  WPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVP 186
            WP+   +        +V + SE V   +T+    ++NI + E+  +  FH+T+WPD GVP
Sbjct: 1153 WPSKQAQ---DYGDITVAMTSEIVLPEWTIRDFTVKNIQTSESHPLRQFHFTSWPDHGVP 1209

Query: 187  ESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQ 246
            ++    +NF + VR+    +P   P ++HCSAG+GR+GTF  +D  +  +E  + +++  
Sbjct: 1210 DTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENTVDVYG 1269

Query: 247  VLLNMRKYRMGLIQTPDQLRF---SYMAIIEGAKCIKGDSSIQKRWKELSKEDLSP 299
            ++ ++R +R  ++QT DQ  F     + I+   K  K D   Q        E+L+P
Sbjct: 1270 IVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQKDSKVDLIYQNTTAMTIYENLAP 1325


>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
            isoform 4 precursor [Homo sapiens]
          Length = 1505

 Score =  187 bits (476), Expect = 1e-47
 Identities = 110/291 (37%), Positives = 154/291 (52%), Gaps = 31/291 (10%)

Query: 5    IEREFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQ 62
            + +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV LQ
Sbjct: 950  LSQEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVILQ 993

Query: 63   NAE----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEK 118
              E    +DYINA+ VD    Q +YI TQGPLP T   FW MVW+Q++  +VM+ R+ EK
Sbjct: 994  PIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEK 1053

Query: 119  ESVKCAQYWPTDDQEMLFKETGF-SVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHY 177
              +KC QYWP    E      GF  V LL     + + V    L    S E R +  F +
Sbjct: 1054 SRIKCDQYWPNRGTETY----GFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1109

Query: 178  TTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLME 237
            T WPD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++
Sbjct: 1110 TAWPDHGVPEYPTPFLAFLRRVKTCNP--PDAGPIVVHCSAGVGRTGCFIVIDAMLERIK 1167

Query: 238  KGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
                +++   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1168 PEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGC--GNTEVPAR 1216



 Score =  158 bits (400), Expect = 7e-39
 Identities = 85/242 (35%), Positives = 132/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1257 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1316

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1317 TTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1373

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1374 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1433

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT D+ +F Y A 
Sbjct: 1434 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAA 1493

Query: 273  IE 274
            +E
Sbjct: 1494 LE 1495


>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
            isoform 2 precursor [Homo sapiens]
          Length = 1910

 Score =  187 bits (476), Expect = 1e-47
 Identities = 110/291 (37%), Positives = 154/291 (52%), Gaps = 31/291 (10%)

Query: 5    IEREFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQ 62
            + +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV LQ
Sbjct: 1355 LSQEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVILQ 1398

Query: 63   NAE----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEK 118
              E    +DYINA+ VD    Q +YI TQGPLP T   FW MVW+Q++  +VM+ R+ EK
Sbjct: 1399 PIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEK 1458

Query: 119  ESVKCAQYWPTDDQEMLFKETGF-SVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHY 177
              +KC QYWP    E      GF  V LL     + + V    L    S E R +  F +
Sbjct: 1459 SRIKCDQYWPNRGTETY----GFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1514

Query: 178  TTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLME 237
            T WPD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++
Sbjct: 1515 TAWPDHGVPEYPTPFLAFLRRVKTCNP--PDAGPIVVHCSAGVGRTGCFIVIDAMLERIK 1572

Query: 238  KGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
                +++   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1573 PEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGC--GNTEVPAR 1621



 Score =  158 bits (400), Expect = 7e-39
 Identities = 85/242 (35%), Positives = 132/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1662 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1721

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1722 TTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1778

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1779 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1838

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT D+ +F Y A 
Sbjct: 1839 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAA 1898

Query: 273  IE 274
            +E
Sbjct: 1899 LE 1900


>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
            isoform 3 precursor [Homo sapiens]
          Length = 1501

 Score =  187 bits (476), Expect = 1e-47
 Identities = 110/291 (37%), Positives = 154/291 (52%), Gaps = 31/291 (10%)

Query: 5    IEREFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQ 62
            + +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV LQ
Sbjct: 946  LSQEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVILQ 989

Query: 63   NAE----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEK 118
              E    +DYINA+ VD    Q +YI TQGPLP T   FW MVW+Q++  +VM+ R+ EK
Sbjct: 990  PIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEK 1049

Query: 119  ESVKCAQYWPTDDQEMLFKETGF-SVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHY 177
              +KC QYWP    E      GF  V LL     + + V    L    S E R +  F +
Sbjct: 1050 SRIKCDQYWPNRGTETY----GFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1105

Query: 178  TTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLME 237
            T WPD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++
Sbjct: 1106 TAWPDHGVPEYPTPFLAFLRRVKTCNP--PDAGPIVVHCSAGVGRTGCFIVIDAMLERIK 1163

Query: 238  KGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
                +++   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1164 PEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGC--GNTEVPAR 1212



 Score =  158 bits (400), Expect = 7e-39
 Identities = 85/242 (35%), Positives = 132/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1253 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1312

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1313 TTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1369

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1370 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1429

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT D+ +F Y A 
Sbjct: 1430 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAA 1489

Query: 273  IE 274
            +E
Sbjct: 1490 LE 1491


>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
            isoform 1 precursor [Homo sapiens]
          Length = 1948

 Score =  187 bits (476), Expect = 1e-47
 Identities = 110/291 (37%), Positives = 154/291 (52%), Gaps = 31/291 (10%)

Query: 5    IEREFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQ 62
            + +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV LQ
Sbjct: 1393 LSQEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVILQ 1436

Query: 63   NAE----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEK 118
              E    +DYINA+ VD    Q +YI TQGPLP T   FW MVW+Q++  +VM+ R+ EK
Sbjct: 1437 PIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEK 1496

Query: 119  ESVKCAQYWPTDDQEMLFKETGF-SVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHY 177
              +KC QYWP    E      GF  V LL     + + V    L    S E R +  F +
Sbjct: 1497 SRIKCDQYWPNRGTETY----GFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1552

Query: 178  TTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLME 237
            T WPD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++
Sbjct: 1553 TAWPDHGVPEYPTPFLAFLRRVKTCNP--PDAGPIVVHCSAGVGRTGCFIVIDAMLERIK 1610

Query: 238  KGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
                +++   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1611 PEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGC--GNTEVPAR 1659



 Score =  158 bits (400), Expect = 7e-39
 Identities = 85/242 (35%), Positives = 132/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1700 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1759

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1760 TTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1816

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1817 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1876

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT D+ +F Y A 
Sbjct: 1877 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAA 1936

Query: 273  IE 274
            +E
Sbjct: 1937 LE 1938


>gi|4506301 protein tyrosine phosphatase, non-receptor type 9 [Homo
           sapiens]
          Length = 593

 Score =  187 bits (474), Expect = 2e-47
 Identities = 108/272 (39%), Positives = 149/272 (54%), Gaps = 18/272 (6%)

Query: 22  YLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQ----NAENDYINASLVDIE 77
           Y +IR E+       +  P N  +NRY DV   D +RVKL     + + DYINAS +D  
Sbjct: 307 YEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGY 366

Query: 78  EAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFK 137
           + + +YI TQGPL NT   FWLMVW+QK   +VM  R  E    KC QYWP +    +  
Sbjct: 367 KQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRI-- 424

Query: 138 ETGF-SVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFL 196
             GF +V  L  +  ++Y    L++ N    + R ++HF + +WPD+GVP S AS ++FL
Sbjct: 425 RFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFL 484

Query: 197 FKVRESGSLNPDH-----------GPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIK 245
             VR   SL   +            P V+HCSAGIGR+GTF  +D CL  +E+   +N+ 
Sbjct: 485 RVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVF 544

Query: 246 QVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAK 277
           Q +  MR  R   IQTP+Q  F Y AI+E A+
Sbjct: 545 QTVSRMRTQRAFSIQTPEQYYFCYKAILEFAE 576


>gi|33356177 protein tyrosine phosphatase, non-receptor type 11
           [Homo sapiens]
          Length = 593

 Score =  185 bits (470), Expect = 5e-47
 Identities = 101/259 (38%), Positives = 152/259 (58%), Gaps = 21/259 (8%)

Query: 32  YPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAE-----NDYINASLVDIE--------E 78
           Y  +  +  EN+N+NRY+++ P+DH+RV L + +     +DYINA+++  E        +
Sbjct: 263 YSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSK 322

Query: 79  AQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKE 138
            ++SYI TQG L NT   FW MV+Q+ ++ +VM  + VE+   KC +YWP    E   KE
Sbjct: 323 PKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWP---DEYALKE 379

Query: 139 TG-FSVKLLSEDVKSYYTVHLLQLENINSGET-RTISHFHYTTWPDFGVPESPASFLNFL 196
            G   V+ + E     YT+  L+L  +  G T RT+  +H+ TWPD GVP  P   L+FL
Sbjct: 380 YGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFL 439

Query: 197 FKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCL-VLMEKG--DDINIKQVLLNMRK 253
            +V        D GP V+HCSAGIGR+GTF ++D  + ++ EKG   DI++ + +  +R 
Sbjct: 440 EEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRS 499

Query: 254 YRMGLIQTPDQLRFSYMAI 272
            R G++QT  Q RF YMA+
Sbjct: 500 QRSGMVQTEAQYRFIYMAV 518


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  185 bits (470), Expect = 5e-47
 Identities = 109/278 (39%), Positives = 146/278 (52%), Gaps = 27/278 (9%)

Query: 7    REFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
            +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV L + 
Sbjct: 1354 QEYESIDPGQQFTWENSNLEV----------------NKPKNRYANVIAYDHSRVILTSI 1397

Query: 65   E----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
            +    +DYINA+ +D    Q +YI TQGPLP T   FW MVW+Q+T  VVM+ R+ EK  
Sbjct: 1398 DGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSR 1457

Query: 121  VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
            VKC QYWP    E         V LL     + YTV    L    S E R +  F +  W
Sbjct: 1458 VKCDQYWPARGTETCGL---IQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAW 1514

Query: 181  PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
            PD GVPE P   L FL +V+    L  D GP V+HCSAG+GR+G F ++D  L  M+   
Sbjct: 1515 PDHGVPEYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEK 1572

Query: 241  DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKC 278
             ++I   +  MR  R  ++QT DQ  F + A++E A C
Sbjct: 1573 TVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATC 1610



 Score =  153 bits (386), Expect = 3e-37
 Identities = 82/242 (33%), Positives = 131/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1659 ANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAE 1718

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            +   FW M+W+  +  +VML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1719 STEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1775

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RTI  F +T WP+ GVP++   F++F+ +V ++       GP 
Sbjct: 1776 QYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPI 1835

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     +++ Q +  +R  R  ++QT DQ +  Y A 
Sbjct: 1836 TVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAA 1895

Query: 273  IE 274
            +E
Sbjct: 1896 LE 1897


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  185 bits (470), Expect = 5e-47
 Identities = 109/278 (39%), Positives = 146/278 (52%), Gaps = 27/278 (9%)

Query: 7    REFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
            +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV L + 
Sbjct: 1345 QEYESIDPGQQFTWENSNLEV----------------NKPKNRYANVIAYDHSRVILTSI 1388

Query: 65   E----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
            +    +DYINA+ +D    Q +YI TQGPLP T   FW MVW+Q+T  VVM+ R+ EK  
Sbjct: 1389 DGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSR 1448

Query: 121  VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
            VKC QYWP    E         V LL     + YTV    L    S E R +  F +  W
Sbjct: 1449 VKCDQYWPARGTETCGL---IQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAW 1505

Query: 181  PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
            PD GVPE P   L FL +V+    L  D GP V+HCSAG+GR+G F ++D  L  M+   
Sbjct: 1506 PDHGVPEYPTPILAFLRRVKACNPL--DAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEK 1563

Query: 241  DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKC 278
             ++I   +  MR  R  ++QT DQ  F + A++E A C
Sbjct: 1564 TVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATC 1601



 Score =  153 bits (386), Expect = 3e-37
 Identities = 82/242 (33%), Positives = 131/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1650 ANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAE 1709

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            +   FW M+W+  +  +VML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1710 STEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1766

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RTI  F +T WP+ GVP++   F++F+ +V ++       GP 
Sbjct: 1767 QYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPI 1826

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     +++ Q +  +R  R  ++QT DQ +  Y A 
Sbjct: 1827 TVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAA 1886

Query: 273  IE 274
            +E
Sbjct: 1887 LE 1888


>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
            precursor [Homo sapiens]
          Length = 1452

 Score =  183 bits (465), Expect = 2e-46
 Identities = 97/262 (37%), Positives = 145/262 (55%), Gaps = 12/262 (4%)

Query: 28   ESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSY 83
            E    P   AK  ENR +NRY ++  YDHSRV+LQ  E    +DYIN + +D       Y
Sbjct: 909  EGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHY 968

Query: 84   ILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSV 143
            I TQGP+  T   FW MVW + T +++M+  +VE   VKC +YWP D +  ++K+    V
Sbjct: 969  IATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTE--IYKD--IKV 1024

Query: 144  KLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESG 203
             L+  ++ + Y +    +E     E R I  FH+T WPD GVP      L F+ +V+   
Sbjct: 1025 TLIETELLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKS 1084

Query: 204  SLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPD 263
               P  GP V+HCSAG GR+G F ++D  L + E+   ++I   +  +R  R+ ++QT +
Sbjct: 1085 P--PSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEE 1142

Query: 264  QLRFSYMAIIEGAKCIKGDSSI 285
            Q  F + AI+E   C+ GD+S+
Sbjct: 1143 QYVFIHDAILEA--CLCGDTSV 1162



 Score =  106 bits (264), Expect = 4e-23
 Identities = 67/246 (27%), Positives = 115/246 (46%), Gaps = 12/246 (4%)

Query: 36   VAKFPENRNRNRYRDVSPYDHSR---VKLQNAENDYINASLVDIEEAQRSYILTQGPLPN 92
            +A  P N  +NR  D+ P D      + +    ++YINA+L+D  +   ++I+TQ PLPN
Sbjct: 1207 IALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPN 1266

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW +V      +VVMLN +    +  C QYWP   +  + +     V+ +S D++ 
Sbjct: 1267 TVKDFWRLVLDYHCTSVVMLNDV--DPAQLCPQYWP---ENGVHRHGPIQVEFVSADLEE 1321

Query: 153  YYTVHLLQLENINSGET--RTISHFHYTTWPDF-GVPESPASFLNFLFKV-RESGSLNPD 208
                 + ++ N    +   R +  F +  WP +   P S  SFL  + +V +     N  
Sbjct: 1322 DIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGG 1381

Query: 209  HGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFS 268
             G  V+HC  G GRSGTF  +     ++     +++   +  +R  +  ++   DQ +F 
Sbjct: 1382 EGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFC 1441

Query: 269  YMAIIE 274
            Y   +E
Sbjct: 1442 YEVALE 1447


>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
            precursor [Homo sapiens]
          Length = 1465

 Score =  183 bits (465), Expect = 2e-46
 Identities = 97/262 (37%), Positives = 145/262 (55%), Gaps = 12/262 (4%)

Query: 28   ESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSY 83
            E    P   AK  ENR +NRY ++  YDHSRV+LQ  E    +DYIN + +D       Y
Sbjct: 922  EGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHY 981

Query: 84   ILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSV 143
            I TQGP+  T   FW MVW + T +++M+  +VE   VKC +YWP D +  ++K+    V
Sbjct: 982  IATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTE--IYKD--IKV 1037

Query: 144  KLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESG 203
             L+  ++ + Y +    +E     E R I  FH+T WPD GVP      L F+ +V+   
Sbjct: 1038 TLIETELLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKS 1097

Query: 204  SLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPD 263
               P  GP V+HCSAG GR+G F ++D  L + E+   ++I   +  +R  R+ ++QT +
Sbjct: 1098 P--PSAGPLVVHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEE 1155

Query: 264  QLRFSYMAIIEGAKCIKGDSSI 285
            Q  F + AI+E   C+ GD+S+
Sbjct: 1156 QYVFIHDAILEA--CLCGDTSV 1175



 Score =  106 bits (264), Expect = 4e-23
 Identities = 67/246 (27%), Positives = 115/246 (46%), Gaps = 12/246 (4%)

Query: 36   VAKFPENRNRNRYRDVSPYDHSR---VKLQNAENDYINASLVDIEEAQRSYILTQGPLPN 92
            +A  P N  +NR  D+ P D      + +    ++YINA+L+D  +   ++I+TQ PLPN
Sbjct: 1220 IALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPN 1279

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW +V      +VVMLN +    +  C QYWP   +  + +     V+ +S D++ 
Sbjct: 1280 TVKDFWRLVLDYHCTSVVMLNDV--DPAQLCPQYWP---ENGVHRHGPIQVEFVSADLEE 1334

Query: 153  YYTVHLLQLENINSGET--RTISHFHYTTWPDF-GVPESPASFLNFLFKV-RESGSLNPD 208
                 + ++ N    +   R +  F +  WP +   P S  SFL  + +V +     N  
Sbjct: 1335 DIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGG 1394

Query: 209  HGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFS 268
             G  V+HC  G GRSGTF  +     ++     +++   +  +R  +  ++   DQ +F 
Sbjct: 1395 EGRTVVHCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFC 1454

Query: 269  YMAIIE 274
            Y   +E
Sbjct: 1455 YEVALE 1460


>gi|194097398 protein tyrosine phosphatase, receptor type, G precursor
            [Homo sapiens]
          Length = 1445

 Score =  178 bits (452), Expect = 6e-45
 Identities = 96/252 (38%), Positives = 145/252 (57%), Gaps = 22/252 (8%)

Query: 40   PENRNRNRYRDVSPYDHSRVKLQ------NAENDYINASLVDIEEAQRSYILTQGPLPNT 93
            PEN+++NRY ++  YDHSRVKL+      +  +DYINA+ VD     ++YI TQGPL +T
Sbjct: 872  PENKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVDGYNKAKAYIATQGPLKST 931

Query: 94   CCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSY 153
               FW M+W+Q T  +VM+  +VEK   KC QYWPT++ E   +     V L S  + + 
Sbjct: 932  FEDFWRMIWEQNTGIIVMITNLVEKGRRKCDQYWPTENSE---EYGNIIVTLKSTKIHAC 988

Query: 154  YTVHLLQLEN--INSGE---------TRTISHFHYTTWPDFGVPESPASFLNFLFKVRES 202
            YTV    + N  +  G+          R +  +HYT WPD GVPE     L F+   R S
Sbjct: 989  YTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQWPDMGVPEYALPVLTFV--RRSS 1046

Query: 203  GSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTP 262
             +  P+ GP ++HCSAG+GR+GT+ ++D+ L  ++    +N+   L ++R  R  L+QT 
Sbjct: 1047 AARMPETGPVLVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTE 1106

Query: 263  DQLRFSYMAIIE 274
            +Q  F + A++E
Sbjct: 1107 EQYIFIHDALLE 1118



 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 73/274 (26%), Positives = 122/274 (44%), Gaps = 25/274 (9%)

Query: 42   NRNRNRYRDVSPYDHSRVKLQNAEN----DYINASLVDIEEAQRSYILTQGPLPNTCCHF 97
            N+ +NR   V P + +RV L         DYINAS +        +I+TQ PLP+T   F
Sbjct: 1175 NKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNEFIITQHPLPHTTKDF 1234

Query: 98   WLMVWQQKTKAVVML---NRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSED----- 149
            W M+W    + +VML     + E E V    YWP+ ++ M  +   F+V L+S+D     
Sbjct: 1235 WRMIWDHNAQIIVMLPDNQSLAEDEFV----YWPSREESMNCE--AFTVTLISKDRLCLS 1288

Query: 150  VKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDH 209
             +    +H   LE         + HF    WP+   P++P S    L  V +  +L  D 
Sbjct: 1289 NEEQIIIHDFILEATQDDYVLEVRHFQCPKWPN---PDAPISSTFELINVIKEEALTRD- 1344

Query: 210  GPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSY 269
            GP ++H   G   +G    + T    +E  + +++ QV   +   R G+    +Q +F Y
Sbjct: 1345 GPTIVHDEYGAVSAGMLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFIY 1404

Query: 270  ---MAIIEGAKCIKGDSSIQKRWKELSKEDLSPA 300
               ++++   +   G  ++ K    L  ++  PA
Sbjct: 1405 KAMLSLVSTKENGNGPMTVDKNGAVLIADESDPA 1438


>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
            [Homo sapiens]
          Length = 1440

 Score =  178 bits (451), Expect = 8e-45
 Identities = 100/256 (39%), Positives = 148/256 (57%), Gaps = 16/256 (6%)

Query: 36   VAKFPENRNRNRYRDVSPYDHSRVKLQNAEND----YINASLVDIEEAQRSYILTQGPLP 91
            VAK  +NR +NRY ++  YDHSRV LQ  E+D    YINA+ +D  +    YI TQGP+ 
Sbjct: 905  VAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVH 964

Query: 92   NTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEML--FKETGFSVKLLSED 149
             T   FW M+WQ+++  +VM+  +VE   VKC +YWP DD E+   FK T   ++ L+E 
Sbjct: 965  ETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP-DDTEVYGDFKVTCVEMEPLAE- 1022

Query: 150  VKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDH 209
                Y V    LE     E R +  FH+T WPD GVP      L+F+ +V+ S    P  
Sbjct: 1023 ----YVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNP--PSA 1076

Query: 210  GPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSY 269
            GP V+HCSAG GR+G + ++D  L + E+   ++I   +  +R  R+ ++QT +Q  F +
Sbjct: 1077 GPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIFIH 1136

Query: 270  MAIIEGAKCIKGDSSI 285
             AI+E   C+ G+++I
Sbjct: 1137 DAILEA--CLCGETAI 1150



 Score =  107 bits (266), Expect = 2e-23
 Identities = 66/246 (26%), Positives = 119/246 (48%), Gaps = 12/246 (4%)

Query: 36   VAKFPENRNRNRYRDVSPYDHSR---VKLQNAENDYINASLVDIEEAQRSYILTQGPLPN 92
            +A  P N ++NR+ D+ P D      + +    ++YINA+L+D      ++I+TQ PLPN
Sbjct: 1195 IACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPN 1254

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW +V+     ++VMLN +    S  C QYWP   +E + +     V+ +S  +  
Sbjct: 1255 TVKDFWRLVYDYGCTSIVMLNEV--DLSQGCPQYWP---EEGMLRYGPIQVECMSCSMDC 1309

Query: 153  YYTVHLLQLENINSGET--RTISHFHYTTWPDF-GVPESPASFLNFLFKVRE-SGSLNPD 208
                 + ++ N+   +     +  F Y  W     VP S  SFL  + +V +        
Sbjct: 1310 DVINRIFRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEG 1369

Query: 209  HGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFS 268
             G  +IHC  G GRSG F  +   + ++++ + +++   +  +R  +  +++ P+Q RF 
Sbjct: 1370 EGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVVDVFHAVKTLRNSKPNMVEAPEQYRFC 1429

Query: 269  YMAIIE 274
            Y   +E
Sbjct: 1430 YDVALE 1435


>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform 5
            precursor [Homo sapiens]
          Length = 1502

 Score =  177 bits (450), Expect = 1e-44
 Identities = 105/288 (36%), Positives = 150/288 (52%), Gaps = 29/288 (10%)

Query: 7    REFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
            +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV L   
Sbjct: 949  QEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVLLSAI 992

Query: 65   E----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
            E    +DY+NA+ +D    Q +YI TQG LP T   FW M+W+Q++  VVM+ ++ E+  
Sbjct: 993  EGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSR 1052

Query: 121  VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
            VKC QYWP+   E         V LL     + Y V    L    S E R +  F +T W
Sbjct: 1053 VKCDQYWPSRGTE---THGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAW 1109

Query: 181  PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
            PD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++   
Sbjct: 1110 PDHGVPEHPTPFLAFLRRVKTCNP--PDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEK 1167

Query: 241  DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
             ++I   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1168 TVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTC--GNTEVPAR 1213



 Score =  161 bits (407), Expect = 1e-39
 Identities = 87/242 (35%), Positives = 133/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1254 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1313

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1314 TTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1370

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1371 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1430

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT DQ +FSY A 
Sbjct: 1431 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAA 1490

Query: 273  IE 274
            +E
Sbjct: 1491 LE 1492


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
            precursor [Homo sapiens]
          Length = 1912

 Score =  177 bits (450), Expect = 1e-44
 Identities = 105/288 (36%), Positives = 150/288 (52%), Gaps = 29/288 (10%)

Query: 7    REFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
            +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV L   
Sbjct: 1359 QEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVLLSAI 1402

Query: 65   E----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
            E    +DY+NA+ +D    Q +YI TQG LP T   FW M+W+Q++  VVM+ ++ E+  
Sbjct: 1403 EGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSR 1462

Query: 121  VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
            VKC QYWP+   E         V LL     + Y V    L    S E R +  F +T W
Sbjct: 1463 VKCDQYWPSRGTE---THGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAW 1519

Query: 181  PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
            PD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++   
Sbjct: 1520 PDHGVPEHPTPFLAFLRRVKTCNP--PDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEK 1577

Query: 241  DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
             ++I   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1578 TVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTC--GNTEVPAR 1623



 Score =  161 bits (407), Expect = 1e-39
 Identities = 87/242 (35%), Positives = 133/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1664 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1723

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1724 TTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1780

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1781 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1840

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT DQ +FSY A 
Sbjct: 1841 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAA 1900

Query: 273  IE 274
            +E
Sbjct: 1901 LE 1902


>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform 2
            precursor [Homo sapiens]
          Length = 1899

 Score =  177 bits (450), Expect = 1e-44
 Identities = 105/288 (36%), Positives = 150/288 (52%), Gaps = 29/288 (10%)

Query: 7    REFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
            +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV L   
Sbjct: 1346 QEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVLLSAI 1389

Query: 65   E----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
            E    +DY+NA+ +D    Q +YI TQG LP T   FW M+W+Q++  VVM+ ++ E+  
Sbjct: 1390 EGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSR 1449

Query: 121  VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
            VKC QYWP+   E         V LL     + Y V    L    S E R +  F +T W
Sbjct: 1450 VKCDQYWPSRGTE---THGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAW 1506

Query: 181  PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
            PD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++   
Sbjct: 1507 PDHGVPEHPTPFLAFLRRVKTCNP--PDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEK 1564

Query: 241  DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
             ++I   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1565 TVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTC--GNTEVPAR 1610



 Score =  161 bits (407), Expect = 1e-39
 Identities = 87/242 (35%), Positives = 133/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1651 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1710

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1711 TTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1767

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1768 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1827

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT DQ +FSY A 
Sbjct: 1828 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAA 1887

Query: 273  IE 274
            +E
Sbjct: 1888 LE 1889


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
            precursor [Homo sapiens]
          Length = 1903

 Score =  177 bits (450), Expect = 1e-44
 Identities = 105/288 (36%), Positives = 150/288 (52%), Gaps = 29/288 (10%)

Query: 7    REFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
            +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV L   
Sbjct: 1350 QEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVLLSAI 1393

Query: 65   E----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
            E    +DY+NA+ +D    Q +YI TQG LP T   FW M+W+Q++  VVM+ ++ E+  
Sbjct: 1394 EGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSR 1453

Query: 121  VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
            VKC QYWP+   E         V LL     + Y V    L    S E R +  F +T W
Sbjct: 1454 VKCDQYWPSRGTE---THGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAW 1510

Query: 181  PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
            PD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++   
Sbjct: 1511 PDHGVPEHPTPFLAFLRRVKTCNP--PDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEK 1568

Query: 241  DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
             ++I   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1569 TVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTC--GNTEVPAR 1614



 Score =  161 bits (407), Expect = 1e-39
 Identities = 87/242 (35%), Positives = 133/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1655 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1714

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1715 TTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1771

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1772 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1831

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT DQ +FSY A 
Sbjct: 1832 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAA 1891

Query: 273  IE 274
            +E
Sbjct: 1892 LE 1893


>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform 4
            precursor [Homo sapiens]
          Length = 1501

 Score =  177 bits (450), Expect = 1e-44
 Identities = 105/288 (36%), Positives = 150/288 (52%), Gaps = 29/288 (10%)

Query: 7    REFEELDT--QRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNA 64
            +E+E +D   Q  W+   LE+                N+ +NRY +V  YDHSRV L   
Sbjct: 948  QEYESIDPGQQFTWEHSNLEV----------------NKPKNRYANVIAYDHSRVLLSAI 991

Query: 65   E----NDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES 120
            E    +DY+NA+ +D    Q +YI TQG LP T   FW M+W+Q++  VVM+ ++ E+  
Sbjct: 992  EGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSR 1051

Query: 121  VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW 180
            VKC QYWP+   E         V LL     + Y V    L    S E R +  F +T W
Sbjct: 1052 VKCDQYWPSRGTE---THGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAW 1108

Query: 181  PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD 240
            PD GVPE P  FL FL +V+      PD GP V+HCSAG+GR+G F ++D  L  ++   
Sbjct: 1109 PDHGVPEHPTPFLAFLRRVKTCNP--PDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEK 1166

Query: 241  DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKR 288
             ++I   +  MR  R  ++QT DQ  F + A++E   C  G++ +  R
Sbjct: 1167 TVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTC--GNTEVPAR 1212



 Score =  161 bits (407), Expect = 1e-39
 Identities = 87/242 (35%), Positives = 133/242 (54%), Gaps = 7/242 (2%)

Query: 37   AKFPENRNRNRYRDVSPYDHSRVKLQNAE----NDYINASLVDIEEAQRSYILTQGPLPN 92
            A  P N+ +NR  ++ PY+ +RV LQ       +DYINAS +D    Q++YI TQGPL  
Sbjct: 1253 ANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAE 1312

Query: 93   TCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKS 152
            T   FW M+W+  +  VVML ++ E    KC QYWP    E   +   F V  ++E    
Sbjct: 1313 TTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPA---ERSARYQYFVVDPMAEYNMP 1369

Query: 153  YYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPA 212
             Y +   ++ +   G++RT+  F +T WP+ GVP+S   F++F+ +V ++       GP 
Sbjct: 1370 QYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPI 1429

Query: 213  VIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAI 272
             +HCSAG+GR+G F  +   L  M     ++I Q +  +R  R  ++QT DQ +FSY A 
Sbjct: 1430 SVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAA 1489

Query: 273  IE 274
            +E
Sbjct: 1490 LE 1491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,724,679
Number of Sequences: 37866
Number of extensions: 652179
Number of successful extensions: 3152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 2491
Number of HSP's gapped (non-prelim): 354
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press