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Search of human proteins with 17986247
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17986247 septin 4 isoform 3 [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17986247 septin 4 isoform 3 [Homo sapiens] 946 0.0
gi|4758942 septin 4 isoform 1 [Homo sapiens] 944 0.0
gi|9945439 septin 5 [Homo sapiens] 576 e-164
gi|17986245 septin 4 isoform 2 [Homo sapiens] 519 e-147
gi|16604248 septin 1 [Homo sapiens] 484 e-137
gi|56549640 septin 2 [Homo sapiens] 436 e-122
gi|56549638 septin 2 [Homo sapiens] 436 e-122
gi|56549636 septin 2 [Homo sapiens] 436 e-122
gi|4758158 septin 2 [Homo sapiens] 436 e-122
gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens] 384 e-107
gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens] 384 e-107
gi|156602655 septin 3 isoform A [Homo sapiens] 314 9e-86
gi|156602653 septin 3 isoform B [Homo sapiens] 314 9e-86
gi|164698502 septin 9 isoform d [Homo sapiens] 310 2e-84
gi|164698500 septin 9 isoform e [Homo sapiens] 309 3e-84
gi|164698498 septin 9 isoform b [Homo sapiens] 309 3e-84
gi|164698496 septin 9 isoform e [Homo sapiens] 309 3e-84
gi|164698494 septin 9 isoform a [Homo sapiens] 309 3e-84
gi|116256489 septin 9 isoform c [Homo sapiens] 309 3e-84
gi|164698504 septin 9 isoform f [Homo sapiens] 306 3e-83
gi|226492421 septin 12 isoform 2 [Homo sapiens] 273 2e-73
gi|149363638 septin 8 isoform c [Homo sapiens] 256 2e-68
gi|149363689 septin 8 isoform a [Homo sapiens] 256 2e-68
gi|149363661 septin 8 isoform b [Homo sapiens] 256 2e-68
gi|8922712 septin 11 [Homo sapiens] 254 1e-67
gi|30795193 septin 10 isoform 2 [Homo sapiens] 252 6e-67
gi|21945064 septin 10 isoform 1 [Homo sapiens] 252 6e-67
gi|21361478 septin 6 isoform B [Homo sapiens] 251 1e-66
gi|22035581 septin 6 isoform D [Homo sapiens] 251 1e-66
gi|22035579 septin 6 isoform A [Homo sapiens] 251 1e-66
>gi|17986247 septin 4 isoform 3 [Homo sapiens]
Length = 459
Score = 946 bits (2446), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR 60
MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR
Sbjct: 1 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR 60
Query: 61 PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV 120
PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV
Sbjct: 61 PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV 120
Query: 121 KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG 180
KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG
Sbjct: 121 KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG 180
Query: 181 VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF 240
VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF
Sbjct: 181 VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF 240
Query: 241 ISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQ 300
ISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQ
Sbjct: 241 ISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQ 300
Query: 301 FPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCD 360
FPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCD
Sbjct: 301 FPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCD 360
Query: 361 FVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIP 420
FVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIP
Sbjct: 361 FVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIP 420
Query: 421 AVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY 459
AVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
Sbjct: 421 AVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY 459
>gi|4758942 septin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 944 bits (2441), Expect = 0.0
Identities = 458/458 (100%), Positives = 458/458 (100%)
Query: 2 IKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFRP 61
IKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFRP
Sbjct: 21 IKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFRP 80
Query: 62 PSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVK 121
PSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVK
Sbjct: 81 PSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVK 140
Query: 122 KGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGV 181
KGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGV
Sbjct: 141 KGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGV 200
Query: 182 RLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFI 241
RLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFI
Sbjct: 201 RLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFI 260
Query: 242 SPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQF 301
SPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQF
Sbjct: 261 SPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQF 320
Query: 302 PDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDF 361
PDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDF
Sbjct: 321 PDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDF 380
Query: 362 VKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPA 421
VKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPA
Sbjct: 381 VKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPA 440
Query: 422 VPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY 459
VPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
Sbjct: 441 VPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY 478
>gi|9945439 septin 5 [Homo sapiens]
Length = 369
Score = 576 bits (1484), Expect = e-164
Identities = 280/364 (76%), Positives = 315/364 (86%), Gaps = 10/364 (2%)
Query: 95 PYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDR 154
P D + DK+YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLV+SLFLTDLY+DR
Sbjct: 14 PEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDR 73
Query: 155 KLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQF 214
KLL AEERI QTVEI KH VDIEEKGV+L+LTIVDTPGFGDAVNNTECWKP+ +Y+DQQF
Sbjct: 74 KLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQF 133
Query: 215 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADT 274
EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRP+DV FMKALH++VNIVP++AKAD
Sbjct: 134 EQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADC 193
Query: 275 LTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVV 334
L P E+ K +IREEI+ FGI +YQFP+CDSDEDEDFK QD+ LKES PFAVIGSNTVV
Sbjct: 194 LVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVV 253
Query: 335 EARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQ 394
EA+G+RVRGRLYPWGIVEVEN HCDFVKLR ML+RTHM DLKDVT + HYENYRA CIQ
Sbjct: 254 EAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQ 313
Query: 395 SMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLIREKDEELRRMQEMLHKIQK 453
MT +KLT++S + PIP +P P D ETEKLIR KDEELRRMQEML ++++
Sbjct: 314 QMT---------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQ 364
Query: 454 QMKE 457
QM++
Sbjct: 365 QMQD 368
>gi|17986245 septin 4 isoform 2 [Homo sapiens]
Length = 274
Score = 519 bits (1336), Expect = e-147
Identities = 248/250 (99%), Positives = 248/250 (99%)
Query: 1 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR 60
MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR
Sbjct: 1 MIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFR 60
Query: 61 PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV 120
PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV
Sbjct: 61 PPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSV 120
Query: 121 KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG 180
KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG
Sbjct: 121 KKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKG 180
Query: 181 VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF 240
VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF
Sbjct: 181 VRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYF 240
Query: 241 ISPFGHGLRP 250
ISPFGHG P
Sbjct: 241 ISPFGHGYGP 250
>gi|16604248 septin 1 [Homo sapiens]
Length = 367
Score = 484 bits (1246), Expect = e-137
Identities = 234/359 (65%), Positives = 294/359 (81%), Gaps = 5/359 (1%)
Query: 102 DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEE 161
DKEYVGFA LPNQ+HRKSVKKGFDFTLMVAGESGLGKSTL+NSLFLT+LY DR++ A
Sbjct: 2 DKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLYEDRQVPEASA 61
Query: 162 RIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDE 221
R+ QT+ I + V+IEE GV+++LT+VDTPGFGD+V+ ++CW PV ++I++QFEQY RDE
Sbjct: 62 RLTQTLAIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVKFIEEQFEQYLRDE 121
Query: 222 SGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD 281
SGLNRKNIQD+RVHCCLYFISPFG GLRPLDV F++A+H++VNI+P++ KAD L P E
Sbjct: 122 SGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPQETQ 181
Query: 282 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRR- 340
K+KIR++++ I IYQFP+CDSDEDEDFK QD +KESIPFAV+GS VV G R
Sbjct: 182 ALKQKIRDQLKEEEIHIYQFPECDSDEDEDFKRQDAEMKESIPFAVVGSCEVVRDGGNRP 241
Query: 341 VRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLV 400
VRGR Y WG VEVENP HCDF+ LR MLV+TH+QDLK+VT + YE YRA+C+QS+ R
Sbjct: 242 VRGRRYSWGTVEVENPHHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPG 301
Query: 401 VKER-NRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKEN 458
++R +R+KL+R+S T+ P+P +P +TEKLIREKDEELRRMQEML K+Q QM+++
Sbjct: 302 ARDRASRSKLSRQSATEIPLPMLPLA---DTEKLIREKDEELRRMQEMLEKMQAQMQQS 357
>gi|56549640 septin 2 [Homo sapiens]
Length = 361
Score = 436 bits (1122), Expect = e-122
Identities = 213/352 (60%), Positives = 272/352 (77%), Gaps = 24/352 (6%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL+NSLFLTDLY +R + GA E+I
Sbjct: 17 YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
+TV+I V+IEE+GV+LRLT+VDTPG+GDA+N +C+K + YID+QFE+Y DESGL
Sbjct: 77 RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136
Query: 225 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 284
NR++I DNRVHCC YFISPFGHGL+PLDV FMKA+H +VNIVP++AKADTLT E + K
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196
Query: 285 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 344
++I +EIE IKIY PD +SDEDEDFK Q + LK SIPF+V+GSN ++EA+G++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256
Query: 345 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKER 404
LYPWG+VEVENP H DF+KLRTML+ THMQDL++VT++ HYEN+R++ ++ R V E
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314
Query: 405 NRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMK 456
D ++++ EK+ ELRRMQEM+ ++Q QM+
Sbjct: 315 ----------------------DMNKDQILLEKEAELRRMQEMIARMQAQMQ 344
>gi|56549638 septin 2 [Homo sapiens]
Length = 361
Score = 436 bits (1122), Expect = e-122
Identities = 213/352 (60%), Positives = 272/352 (77%), Gaps = 24/352 (6%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL+NSLFLTDLY +R + GA E+I
Sbjct: 17 YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
+TV+I V+IEE+GV+LRLT+VDTPG+GDA+N +C+K + YID+QFE+Y DESGL
Sbjct: 77 RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136
Query: 225 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 284
NR++I DNRVHCC YFISPFGHGL+PLDV FMKA+H +VNIVP++AKADTLT E + K
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196
Query: 285 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 344
++I +EIE IKIY PD +SDEDEDFK Q + LK SIPF+V+GSN ++EA+G++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256
Query: 345 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKER 404
LYPWG+VEVENP H DF+KLRTML+ THMQDL++VT++ HYEN+R++ ++ R V E
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314
Query: 405 NRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMK 456
D ++++ EK+ ELRRMQEM+ ++Q QM+
Sbjct: 315 ----------------------DMNKDQILLEKEAELRRMQEMIARMQAQMQ 344
>gi|56549636 septin 2 [Homo sapiens]
Length = 361
Score = 436 bits (1122), Expect = e-122
Identities = 213/352 (60%), Positives = 272/352 (77%), Gaps = 24/352 (6%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL+NSLFLTDLY +R + GA E+I
Sbjct: 17 YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
+TV+I V+IEE+GV+LRLT+VDTPG+GDA+N +C+K + YID+QFE+Y DESGL
Sbjct: 77 RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136
Query: 225 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 284
NR++I DNRVHCC YFISPFGHGL+PLDV FMKA+H +VNIVP++AKADTLT E + K
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196
Query: 285 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 344
++I +EIE IKIY PD +SDEDEDFK Q + LK SIPF+V+GSN ++EA+G++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256
Query: 345 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKER 404
LYPWG+VEVENP H DF+KLRTML+ THMQDL++VT++ HYEN+R++ ++ R V E
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314
Query: 405 NRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMK 456
D ++++ EK+ ELRRMQEM+ ++Q QM+
Sbjct: 315 ----------------------DMNKDQILLEKEAELRRMQEMIARMQAQMQ 344
>gi|4758158 septin 2 [Homo sapiens]
Length = 361
Score = 436 bits (1122), Expect = e-122
Identities = 213/352 (60%), Positives = 272/352 (77%), Gaps = 24/352 (6%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
YVGFA LPNQVHRKSVKKGF+FTLMV GESGLGKSTL+NSLFLTDLY +R + GA E+I
Sbjct: 17 YVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLINSLFLTDLYPERVIPGAAEKIE 76
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
+TV+I V+IEE+GV+LRLT+VDTPG+GDA+N +C+K + YID+QFE+Y DESGL
Sbjct: 77 RTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKTIISYIDEQFERYLHDESGL 136
Query: 225 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 284
NR++I DNRVHCC YFISPFGHGL+PLDV FMKA+H +VNIVP++AKADTLT E + K
Sbjct: 137 NRRHIIDNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPVIAKADTLTLKERERLK 196
Query: 285 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 344
++I +EIE IKIY PD +SDEDEDFK Q + LK SIPF+V+GSN ++EA+G++VRGR
Sbjct: 197 KRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQLIEAKGKKVRGR 256
Query: 345 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKER 404
LYPWG+VEVENP H DF+KLRTML+ THMQDL++VT++ HYEN+R++ ++ R V E
Sbjct: 257 LYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGRKVENE- 314
Query: 405 NRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMK 456
D ++++ EK+ ELRRMQEM+ ++Q QM+
Sbjct: 315 ----------------------DMNKDQILLEKEAELRRMQEMIARMQAQMQ 344
>gi|148352331 cell division cycle 10 isoform 1 [Homo sapiens]
Length = 437
Score = 384 bits (987), Expect = e-107
Identities = 191/364 (52%), Positives = 257/364 (70%), Gaps = 14/364 (3%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
YVGFA LPNQV+RKSVK+GF+FTLMV GESGLGKSTL+NSLFLTDLY + G RI
Sbjct: 30 YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 88
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
+TV++ + V I+E GV+L LTIVDTPGFGDAV+N+ CW+PV +YID +FE Y ES +
Sbjct: 89 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 148
Query: 225 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 284
NR+ + DNRV CCLYFI+P GHGL+PLD+EFMK LH++VNI+P++AKADTLTP E K
Sbjct: 149 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 208
Query: 285 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 344
++I +EI+ IKIY+FP+ D +E+ + +K+ +P AV+GSNT++E G+RVRGR
Sbjct: 209 KQIMKEIQEHKIKIYEFPETDDEEENKLV---KKIKDRLPLAVVGSNTIIEVNGKRVRGR 265
Query: 345 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMT-RLVVKE 403
YPWG+ EVEN HCDF LR ML+RTHMQDLKDVT HYENYR++ + ++T V
Sbjct: 266 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNN 325
Query: 404 RNRNKLTRESGTDF---------PIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQ 454
+N+ +LT+ + + + E ++EK ++L+ + L + +Q
Sbjct: 326 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQ 385
Query: 455 MKEN 458
MK+N
Sbjct: 386 MKKN 389
>gi|148352329 cell division cycle 10 isoform 2 [Homo sapiens]
Length = 436
Score = 384 bits (987), Expect = e-107
Identities = 191/364 (52%), Positives = 257/364 (70%), Gaps = 14/364 (3%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
YVGFA LPNQV+RKSVK+GF+FTLMV GESGLGKSTL+NSLFLTDLY + G RI
Sbjct: 29 YVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSP-EYPGPSHRIK 87
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
+TV++ + V I+E GV+L LTIVDTPGFGDAV+N+ CW+PV +YID +FE Y ES +
Sbjct: 88 KTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRV 147
Query: 225 NRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKK 284
NR+ + DNRV CCLYFI+P GHGL+PLD+EFMK LH++VNI+P++AKADTLTP E K
Sbjct: 148 NRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFK 207
Query: 285 RKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGR 344
++I +EI+ IKIY+FP+ D +E+ + +K+ +P AV+GSNT++E G+RVRGR
Sbjct: 208 KQIMKEIQEHKIKIYEFPETDDEEENKLV---KKIKDRLPLAVVGSNTIIEVNGKRVRGR 264
Query: 345 LYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMT-RLVVKE 403
YPWG+ EVEN HCDF LR ML+RTHMQDLKDVT HYENYR++ + ++T V
Sbjct: 265 QYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNN 324
Query: 404 RNRNKLTRESGTDF---------PIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQ 454
+N+ +LT+ + + + E ++EK ++L+ + L + +Q
Sbjct: 325 KNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQ 384
Query: 455 MKEN 458
MK+N
Sbjct: 385 MKKN 388
>gi|156602655 septin 3 isoform A [Homo sapiens]
Length = 358
Score = 314 bits (805), Expect = 9e-86
Identities = 157/318 (49%), Positives = 219/318 (68%), Gaps = 5/318 (1%)
Query: 76 APAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESG 135
A + L P RP+ P + P + + Y+G T+ Q+ +K++K GFDF +MV G+SG
Sbjct: 13 AMSELVPEPRPK-PAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSG 71
Query: 136 LGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGD 195
LGKSTLVN+LF + + R EE+I +TVEI IEE GV+++LT++DTPGFGD
Sbjct: 72 LGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGD 131
Query: 196 AVNNTECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVE 254
+NN CW+P+ +YI++Q+E++ ++E + R K I D RVHCCLYFISP GH LRPLD+E
Sbjct: 132 QINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLE 191
Query: 255 FMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDED-EDFK 313
FMK L + VNI+P++AKADT+T E K+++R+E+E GI+ Y P + DED ED
Sbjct: 192 FMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFY--PQKEFDEDLEDKT 249
Query: 314 LQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHM 373
D+ +ES+PFAV+GS+ + G+RV GR PWGI+EVEN HC+F LR ++RTH+
Sbjct: 250 ENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHL 309
Query: 374 QDLKDVTRETHYENYRAQ 391
QDLK+VT HYE YRA+
Sbjct: 310 QDLKEVTHNIHYETYRAK 327
>gi|156602653 septin 3 isoform B [Homo sapiens]
Length = 350
Score = 314 bits (805), Expect = 9e-86
Identities = 157/318 (49%), Positives = 219/318 (68%), Gaps = 5/318 (1%)
Query: 76 APAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESG 135
A + L P RP+ P + P + + Y+G T+ Q+ +K++K GFDF +MV G+SG
Sbjct: 13 AMSELVPEPRPK-PAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSG 71
Query: 136 LGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGD 195
LGKSTLVN+LF + + R EE+I +TVEI IEE GV+++LT++DTPGFGD
Sbjct: 72 LGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGD 131
Query: 196 AVNNTECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVE 254
+NN CW+P+ +YI++Q+E++ ++E + R K I D RVHCCLYFISP GH LRPLD+E
Sbjct: 132 QINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLE 191
Query: 255 FMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDED-EDFK 313
FMK L + VNI+P++AKADT+T E K+++R+E+E GI+ Y P + DED ED
Sbjct: 192 FMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFY--PQKEFDEDLEDKT 249
Query: 314 LQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHM 373
D+ +ES+PFAV+GS+ + G+RV GR PWGI+EVEN HC+F LR ++RTH+
Sbjct: 250 ENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHL 309
Query: 374 QDLKDVTRETHYENYRAQ 391
QDLK+VT HYE YRA+
Sbjct: 310 QDLKEVTHNIHYETYRAK 327
>gi|164698502 septin 9 isoform d [Homo sapiens]
Length = 474
Score = 310 bits (793), Expect = 2e-84
Identities = 161/343 (46%), Positives = 226/343 (65%), Gaps = 9/343 (2%)
Query: 54 DDDLEFRPPSRPQSSDNQQYFCAPAPLSPSA-RPRSPWGKLDPYDSSED---DKEYVGFA 109
+DDL F + SD Q AP+ + A PR K P +E D YVG
Sbjct: 113 EDDLAFCLATI--GSDRQATEAAPSCVGDMADTPRDAGLKQAPASRNEKAPVDFGYVGID 170
Query: 110 TLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEI 169
++ Q+ RK++K+GF+F +MV G+SGLGKSTL+N+LF + + R +EERI +T+EI
Sbjct: 171 SILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEI 230
Query: 170 TKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNR-KN 228
DIEEKGVR++LT++DTPGFGD +NN CW+P+ ++I+ Q+E+Y ++E +NR K
Sbjct: 231 KSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKR 290
Query: 229 IQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIR 288
I D RVHCCLYFI GH LRPLD+EFMK L + VNIVP++AKADTLT E H K++I
Sbjct: 291 IPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVHFKQRIT 350
Query: 289 EEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPW 348
++ GI +Y P + DED + +L ++ +E IPFAV+GS+ + G+R+ GR W
Sbjct: 351 ADLLSNGIDVY--PQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKW 408
Query: 349 GIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQ 391
G +EVEN HC+F LR +L+RTHMQ++KD+T H+E YR +
Sbjct: 409 GTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVK 451
>gi|164698500 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 309 bits (792), Expect = 3e-84
Identities = 168/373 (45%), Positives = 236/373 (63%), Gaps = 15/373 (4%)
Query: 30 PPEAKTWASRPQVPEPRPQAP-DLYDDDLEFRPP-----SRPQSSDNQQYFCAPAPLSPS 83
P EA T S Q E AP LE +P + P+S + + AP+ +
Sbjct: 31 PAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATE--AAPSCVGDM 88
Query: 84 A-RPRSPWGKLDPYDSSED---DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS 139
A PR K P +E D YVG ++ Q+ RK++K+GF+F +MV G+SGLGKS
Sbjct: 89 ADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKS 148
Query: 140 TLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN 199
TL+N+LF + + R +EERI +T+EI DIEEKGVR++LT++DTPGFGD +NN
Sbjct: 149 TLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINN 208
Query: 200 TECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKA 258
CW+P+ ++I+ Q+E+Y ++E +NR K I D RVHCCLYFI GH LRPLD+EFMK
Sbjct: 209 ENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKR 268
Query: 259 LHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQA 318
L + VNIVP++AKADTLT E H K++I ++ GI +Y P + DED + +L ++
Sbjct: 269 LSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEK 326
Query: 319 LKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKD 378
+E IPFAV+GS+ + G+R+ GR WG +EVEN HC+F LR +L+RTHMQ++KD
Sbjct: 327 FREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKD 386
Query: 379 VTRETHYENYRAQ 391
+T H+E YR +
Sbjct: 387 ITSSIHFEAYRVK 399
>gi|164698498 septin 9 isoform b [Homo sapiens]
Length = 579
Score = 309 bits (792), Expect = 3e-84
Identities = 168/373 (45%), Positives = 236/373 (63%), Gaps = 15/373 (4%)
Query: 30 PPEAKTWASRPQVPEPRPQAP-DLYDDDLEFRPP-----SRPQSSDNQQYFCAPAPLSPS 83
P EA T S Q E AP LE +P + P+S + + AP+ +
Sbjct: 188 PAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATE--AAPSCVGDM 245
Query: 84 A-RPRSPWGKLDPYDSSED---DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS 139
A PR K P +E D YVG ++ Q+ RK++K+GF+F +MV G+SGLGKS
Sbjct: 246 ADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKS 305
Query: 140 TLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN 199
TL+N+LF + + R +EERI +T+EI DIEEKGVR++LT++DTPGFGD +NN
Sbjct: 306 TLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINN 365
Query: 200 TECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKA 258
CW+P+ ++I+ Q+E+Y ++E +NR K I D RVHCCLYFI GH LRPLD+EFMK
Sbjct: 366 ENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKR 425
Query: 259 LHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQA 318
L + VNIVP++AKADTLT E H K++I ++ GI +Y P + DED + +L ++
Sbjct: 426 LSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEK 483
Query: 319 LKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKD 378
+E IPFAV+GS+ + G+R+ GR WG +EVEN HC+F LR +L+RTHMQ++KD
Sbjct: 484 FREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKD 543
Query: 379 VTRETHYENYRAQ 391
+T H+E YR +
Sbjct: 544 ITSSIHFEAYRVK 556
>gi|164698496 septin 9 isoform e [Homo sapiens]
Length = 422
Score = 309 bits (792), Expect = 3e-84
Identities = 168/373 (45%), Positives = 236/373 (63%), Gaps = 15/373 (4%)
Query: 30 PPEAKTWASRPQVPEPRPQAP-DLYDDDLEFRPP-----SRPQSSDNQQYFCAPAPLSPS 83
P EA T S Q E AP LE +P + P+S + + AP+ +
Sbjct: 31 PAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATE--AAPSCVGDM 88
Query: 84 A-RPRSPWGKLDPYDSSED---DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS 139
A PR K P +E D YVG ++ Q+ RK++K+GF+F +MV G+SGLGKS
Sbjct: 89 ADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKS 148
Query: 140 TLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN 199
TL+N+LF + + R +EERI +T+EI DIEEKGVR++LT++DTPGFGD +NN
Sbjct: 149 TLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINN 208
Query: 200 TECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKA 258
CW+P+ ++I+ Q+E+Y ++E +NR K I D RVHCCLYFI GH LRPLD+EFMK
Sbjct: 209 ENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKR 268
Query: 259 LHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQA 318
L + VNIVP++AKADTLT E H K++I ++ GI +Y P + DED + +L ++
Sbjct: 269 LSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEK 326
Query: 319 LKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKD 378
+E IPFAV+GS+ + G+R+ GR WG +EVEN HC+F LR +L+RTHMQ++KD
Sbjct: 327 FREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKD 386
Query: 379 VTRETHYENYRAQ 391
+T H+E YR +
Sbjct: 387 ITSSIHFEAYRVK 399
>gi|164698494 septin 9 isoform a [Homo sapiens]
Length = 586
Score = 309 bits (792), Expect = 3e-84
Identities = 168/373 (45%), Positives = 236/373 (63%), Gaps = 15/373 (4%)
Query: 30 PPEAKTWASRPQVPEPRPQAP-DLYDDDLEFRPP-----SRPQSSDNQQYFCAPAPLSPS 83
P EA T S Q E AP LE +P + P+S + + AP+ +
Sbjct: 195 PAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATE--AAPSCVGDM 252
Query: 84 A-RPRSPWGKLDPYDSSED---DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS 139
A PR K P +E D YVG ++ Q+ RK++K+GF+F +MV G+SGLGKS
Sbjct: 253 ADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKS 312
Query: 140 TLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN 199
TL+N+LF + + R +EERI +T+EI DIEEKGVR++LT++DTPGFGD +NN
Sbjct: 313 TLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINN 372
Query: 200 TECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKA 258
CW+P+ ++I+ Q+E+Y ++E +NR K I D RVHCCLYFI GH LRPLD+EFMK
Sbjct: 373 ENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKR 432
Query: 259 LHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQA 318
L + VNIVP++AKADTLT E H K++I ++ GI +Y P + DED + +L ++
Sbjct: 433 LSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEK 490
Query: 319 LKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKD 378
+E IPFAV+GS+ + G+R+ GR WG +EVEN HC+F LR +L+RTHMQ++KD
Sbjct: 491 FREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKD 550
Query: 379 VTRETHYENYRAQ 391
+T H+E YR +
Sbjct: 551 ITSSIHFEAYRVK 563
>gi|116256489 septin 9 isoform c [Homo sapiens]
Length = 568
Score = 309 bits (792), Expect = 3e-84
Identities = 168/373 (45%), Positives = 236/373 (63%), Gaps = 15/373 (4%)
Query: 30 PPEAKTWASRPQVPEPRPQAP-DLYDDDLEFRPP-----SRPQSSDNQQYFCAPAPLSPS 83
P EA T S Q E AP LE +P + P+S + + AP+ +
Sbjct: 177 PAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATE--AAPSCVGDM 234
Query: 84 A-RPRSPWGKLDPYDSSED---DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS 139
A PR K P +E D YVG ++ Q+ RK++K+GF+F +MV G+SGLGKS
Sbjct: 235 ADTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKS 294
Query: 140 TLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN 199
TL+N+LF + + R +EERI +T+EI DIEEKGVR++LT++DTPGFGD +NN
Sbjct: 295 TLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINN 354
Query: 200 TECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKA 258
CW+P+ ++I+ Q+E+Y ++E +NR K I D RVHCCLYFI GH LRPLD+EFMK
Sbjct: 355 ENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKR 414
Query: 259 LHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQA 318
L + VNIVP++AKADTLT E H K++I ++ GI +Y P + DED + +L ++
Sbjct: 415 LSKVVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEK 472
Query: 319 LKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKD 378
+E IPFAV+GS+ + G+R+ GR WG +EVEN HC+F LR +L+RTHMQ++KD
Sbjct: 473 FREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKD 532
Query: 379 VTRETHYENYRAQ 391
+T H+E YR +
Sbjct: 533 ITSSIHFEAYRVK 545
>gi|164698504 septin 9 isoform f [Homo sapiens]
Length = 335
Score = 306 bits (784), Expect = 3e-83
Identities = 151/310 (48%), Positives = 212/310 (68%), Gaps = 6/310 (1%)
Query: 86 PRSPWGKLDPYDSSED---DKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLV 142
PR K P +E D YVG ++ Q+ RK++K+GF+F +MV G+SGLGKSTL+
Sbjct: 5 PRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLI 64
Query: 143 NSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTEC 202
N+LF + + R +EERI +T+EI DIEEKGVR++LT++DTPGFGD +NN C
Sbjct: 65 NTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENC 124
Query: 203 WKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQ 261
W+P+ ++I+ Q+E+Y ++E +NR K I D RVHCCLYFI GH LRPLD+EFMK L +
Sbjct: 125 WQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSK 184
Query: 262 RVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKE 321
VNIVP++AKADTLT E H K++I ++ GI +Y P + DED + +L ++ +E
Sbjct: 185 VVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVY--PQKEFDEDSEDRLVNEKFRE 242
Query: 322 SIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTR 381
IPFAV+GS+ + G+R+ GR WG +EVEN HC+F LR +L+RTHMQ++KD+T
Sbjct: 243 MIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITS 302
Query: 382 ETHYENYRAQ 391
H+E YR +
Sbjct: 303 SIHFEAYRVK 312
>gi|226492421 septin 12 isoform 2 [Homo sapiens]
Length = 358
Score = 273 bits (698), Expect = 2e-73
Identities = 151/361 (41%), Positives = 219/361 (60%), Gaps = 18/361 (4%)
Query: 80 LSPSARPRSPWGKLDPYDSSEDDKEY---VGFATLPNQVHRKSVKKGFDFTLMVAGESGL 136
+ P R SP P S E VG + +Q+ K++K GF+F +MV G+SGL
Sbjct: 1 MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGL 60
Query: 137 GKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDA 196
GKST+VN+LF + +++ G QT+++ IEEKGV+L+LT+ DTPGFGD
Sbjct: 61 GKSTMVNTLFKSKVWKSNPP-GLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQ 119
Query: 197 VNNTECWKPVAEYIDQQFEQYFRDESGLNR-KNIQDNRVHCCLYFISPFGHGLRPLDVEF 255
+NN CW P+ YI++Q+EQY ++E + R ++I D RVHCC+YF+ P GH LRPLD+EF
Sbjct: 120 INNDNCWDPILGYINEQYEQYLQEEILITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEF 179
Query: 256 MKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQ 315
++ L + VN+VP++A+AD+LT E + +R+I++ + I +Y P DED + K+
Sbjct: 180 LQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVY--PQMCFDEDINDKIL 237
Query: 316 DQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQD 375
+ L++ IPFAV+G++ GR V GR WGI+EVEN HC+F LR +L+R+H+QD
Sbjct: 238 NSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQD 297
Query: 376 LKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPG-TDPETEKLI 434
LKD+T HYENYR V++ + L R G PA P T P T K+
Sbjct: 298 LKDITHNIHYENYR----------VIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVC 347
Query: 435 R 435
R
Sbjct: 348 R 348
>gi|149363638 septin 8 isoform c [Homo sapiens]
Length = 442
Score = 256 bits (655), Expect = 2e-68
Identities = 140/367 (38%), Positives = 210/367 (57%), Gaps = 24/367 (6%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ KSV +GF F ++ GE+G+GKSTL+N+LF T +
Sbjct: 24 HVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEA-----SHHE 78
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
V + D++E V+L+LTIVD GFGD +N E ++P+ +YID QFE Y ++E +
Sbjct: 79 ACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKI 138
Query: 225 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 282
R + D R+H CLYFI+P GH L+ LD+ MK L +VNI+PI+AKADT++ E+
Sbjct: 139 RRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHK 198
Query: 283 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 342
K KI E+ G++IYQFP +DE + + +PFAV+GS V+ + VR
Sbjct: 199 FKIKIMGELVSNGVQIYQFPT----DDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVR 254
Query: 343 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSM------ 396
R YPWG+V+VEN HCDFVKLR ML+R +M+DL++ T HYE YR ++ M
Sbjct: 255 ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSD 314
Query: 397 -------TRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLH 449
+ + + + L+ + + + ETE ++EK+ EL E L
Sbjct: 315 GDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLK 374
Query: 450 KIQKQMK 456
++ ++ K
Sbjct: 375 RVHQEEK 381
>gi|149363689 septin 8 isoform a [Homo sapiens]
Length = 483
Score = 256 bits (655), Expect = 2e-68
Identities = 140/367 (38%), Positives = 210/367 (57%), Gaps = 24/367 (6%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ KSV +GF F ++ GE+G+GKSTL+N+LF T +
Sbjct: 24 HVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEA-----SHHE 78
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
V + D++E V+L+LTIVD GFGD +N E ++P+ +YID QFE Y ++E +
Sbjct: 79 ACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKI 138
Query: 225 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 282
R + D R+H CLYFI+P GH L+ LD+ MK L +VNI+PI+AKADT++ E+
Sbjct: 139 RRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHK 198
Query: 283 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 342
K KI E+ G++IYQFP +DE + + +PFAV+GS V+ + VR
Sbjct: 199 FKIKIMGELVSNGVQIYQFPT----DDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVR 254
Query: 343 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSM------ 396
R YPWG+V+VEN HCDFVKLR ML+R +M+DL++ T HYE YR ++ M
Sbjct: 255 ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSD 314
Query: 397 -------TRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLH 449
+ + + + L+ + + + ETE ++EK+ EL E L
Sbjct: 315 GDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLK 374
Query: 450 KIQKQMK 456
++ ++ K
Sbjct: 375 RVHQEEK 381
>gi|149363661 septin 8 isoform b [Homo sapiens]
Length = 429
Score = 256 bits (655), Expect = 2e-68
Identities = 140/367 (38%), Positives = 210/367 (57%), Gaps = 24/367 (6%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ KSV +GF F ++ GE+G+GKSTL+N+LF T +
Sbjct: 24 HVGFDSLPDQLVSKSVTQGFSFNILCVGETGIGKSTLMNTLFNTTFETEEA-----SHHE 78
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
V + D++E V+L+LTIVD GFGD +N E ++P+ +YID QFE Y ++E +
Sbjct: 79 ACVRLRPQTYDLQESNVQLKLTIVDAVGFGDQINKDESYRPIVDYIDAQFENYLQEELKI 138
Query: 225 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 282
R + D R+H CLYFI+P GH L+ LD+ MK L +VNI+PI+AKADT++ E+
Sbjct: 139 RRSLFDYHDTRIHVCLYFITPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELHK 198
Query: 283 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 342
K KI E+ G++IYQFP +DE + + +PFAV+GS V+ + VR
Sbjct: 199 FKIKIMGELVSNGVQIYQFPT----DDEAVAEINAVMNAHLPFAVVGSTEEVKVGNKLVR 254
Query: 343 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSM------ 396
R YPWG+V+VEN HCDFVKLR ML+R +M+DL++ T HYE YR ++ M
Sbjct: 255 ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSD 314
Query: 397 -------TRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLH 449
+ + + + L+ + + + ETE ++EK+ EL E L
Sbjct: 315 GDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLK 374
Query: 450 KIQKQMK 456
++ ++ K
Sbjct: 375 RVHQEEK 381
>gi|8922712 septin 11 [Homo sapiens]
Length = 429
Score = 254 bits (648), Expect = 1e-67
Identities = 142/365 (38%), Positives = 211/365 (57%), Gaps = 28/365 (7%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ KS +GF F ++ GE+G+GKSTL+++LF T D
Sbjct: 21 HVGFDSLPDQLVNKSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPG--- 77
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
V + + +++E VRL+LTIVDT GFGD +N + +KP+ EYID QFE Y ++E +
Sbjct: 78 --VRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKI 135
Query: 225 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 282
R N D R+H CLYFI+P GH L+ LD+ MK L +VNI+PI+AKADT+ E+
Sbjct: 136 KRSLFNYHDTRIHACLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHK 195
Query: 283 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 342
K KI E+ G++IYQFP +DE+ ++ + + +PFAV+GS V+ + +
Sbjct: 196 FKSKIMSELVSNGVQIYQFP---TDEETVAEI-NATMSVHLPFAVVGSTEEVKIGNKMAK 251
Query: 343 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVK 402
R YPWG+V+VEN HCDFVKLR ML+R +M+DL++ T HYE YR ++ M
Sbjct: 252 ARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEM------ 305
Query: 403 ERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEM--------LHKIQKQ 454
K T F + E +++K+EE+R+M M L + +K+
Sbjct: 306 ---GFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKE 362
Query: 455 MKENY 459
+ E +
Sbjct: 363 LHEKF 367
>gi|30795193 septin 10 isoform 2 [Homo sapiens]
Length = 431
Score = 252 bits (643), Expect = 6e-67
Identities = 129/311 (41%), Positives = 200/311 (64%), Gaps = 11/311 (3%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ +S+++GF F ++ GE+G+GKSTL+++LF T+ + D +
Sbjct: 23 HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 77
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
V++ +++E V+L+LTIV+T GFGD +N E ++P+ +YID QFE Y ++E +
Sbjct: 78 PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 137
Query: 225 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 282
R D+R+H CLYFISP GH L+ LD+ MK L +VNI+P++AKADT++ E+
Sbjct: 138 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 197
Query: 283 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 342
K K+ E+ G++IYQFP +D+D K+ + A+ +PFAV+GS V+ + V+
Sbjct: 198 FKIKLMSELVSNGVQIYQFP---TDDDTIAKV-NAAMNGQLPFAVVGSMDEVKVGNKMVK 253
Query: 343 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVK 402
R YPWG+V+VEN HCDFVKLR ML+ T+M+DL++ T HYE YR ++ M V
Sbjct: 254 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVG 313
Query: 403 ERNRNKLTRES 413
N+ +E+
Sbjct: 314 PENKPVSVQET 324
>gi|21945064 septin 10 isoform 1 [Homo sapiens]
Length = 454
Score = 252 bits (643), Expect = 6e-67
Identities = 129/311 (41%), Positives = 200/311 (64%), Gaps = 11/311 (3%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ +S+++GF F ++ GE+G+GKSTL+++LF T+ + D +
Sbjct: 46 HVGFESLPDQLVNRSIQQGFCFNILCVGETGIGKSTLIDTLFNTN-FEDYE----SSHFC 100
Query: 165 QTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGL 224
V++ +++E V+L+LTIV+T GFGD +N E ++P+ +YID QFE Y ++E +
Sbjct: 101 PNVKLKAQTYELQESNVQLKLTIVNTVGFGDQINKEESYQPIVDYIDAQFEAYLQEELKI 160
Query: 225 NRK--NIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDH 282
R D+R+H CLYFISP GH L+ LD+ MK L +VNI+P++AKADT++ E+
Sbjct: 161 KRSLFTYHDSRIHVCLYFISPTGHSLKTLDLLTMKNLDSKVNIIPVIAKADTVSKTELQK 220
Query: 283 KKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVR 342
K K+ E+ G++IYQFP +D+D K+ + A+ +PFAV+GS V+ + V+
Sbjct: 221 FKIKLMSELVSNGVQIYQFP---TDDDTIAKV-NAAMNGQLPFAVVGSMDEVKVGNKMVK 276
Query: 343 GRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVK 402
R YPWG+V+VEN HCDFVKLR ML+ T+M+DL++ T HYE YR ++ M V
Sbjct: 277 ARQYPWGVVQVENENHCDFVKLREMLICTNMEDLREQTHTRHYELYRRCKLEEMGFTDVG 336
Query: 403 ERNRNKLTRES 413
N+ +E+
Sbjct: 337 PENKPVSVQET 347
>gi|21361478 septin 6 isoform B [Homo sapiens]
Length = 434
Score = 251 bits (640), Expect = 1e-66
Identities = 144/356 (40%), Positives = 207/356 (58%), Gaps = 39/356 (10%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ KSV +GF F ++ GE+GLGKSTL+++LF T K G
Sbjct: 22 HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNT------KFEGEPATHT 75
Query: 165 QT-VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESG 223
Q V++ + D++E VRL+LTIV T GFGD +N + +KP+ E+ID QFE Y ++E
Sbjct: 76 QPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELK 135
Query: 224 LNR--KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD 281
+ R D+R+H CLYFI+P GH L+ LD+ MK L +VNI+PI+AKAD ++ E+
Sbjct: 136 IRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELT 195
Query: 282 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRV 341
K KI E+ G++IYQFP +DE + + +PFAVIGS ++ + +
Sbjct: 196 KFKIKITSELVSNGVQIYQFPT----DDESVAEINGTMNAHLPFAVIGSTEELKIGNKMM 251
Query: 342 RGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVV 401
R R YPWG V+VEN HCDFVKLR ML+R +M+DL++ T HYE YR
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYR------------ 299
Query: 402 KERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKE 457
R KL D TDP+++ ++ E +R E L ++QK+ +E
Sbjct: 300 ----RCKLEEMGFKD---------TDPDSKPFSLQETYEAKR-NEFLGELQKKEEE 341
>gi|22035581 septin 6 isoform D [Homo sapiens]
Length = 429
Score = 251 bits (640), Expect = 1e-66
Identities = 144/356 (40%), Positives = 207/356 (58%), Gaps = 39/356 (10%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ KSV +GF F ++ GE+GLGKSTL+++LF T K G
Sbjct: 22 HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNT------KFEGEPATHT 75
Query: 165 QT-VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESG 223
Q V++ + D++E VRL+LTIV T GFGD +N + +KP+ E+ID QFE Y ++E
Sbjct: 76 QPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELK 135
Query: 224 LNR--KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD 281
+ R D+R+H CLYFI+P GH L+ LD+ MK L +VNI+PI+AKAD ++ E+
Sbjct: 136 IRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELT 195
Query: 282 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRV 341
K KI E+ G++IYQFP +DE + + +PFAVIGS ++ + +
Sbjct: 196 KFKIKITSELVSNGVQIYQFPT----DDESVAEINGTMNAHLPFAVIGSTEELKIGNKMM 251
Query: 342 RGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVV 401
R R YPWG V+VEN HCDFVKLR ML+R +M+DL++ T HYE YR
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYR------------ 299
Query: 402 KERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKE 457
R KL D TDP+++ ++ E +R E L ++QK+ +E
Sbjct: 300 ----RCKLEEMGFKD---------TDPDSKPFSLQETYEAKR-NEFLGELQKKEEE 341
>gi|22035579 septin 6 isoform A [Homo sapiens]
Length = 427
Score = 251 bits (640), Expect = 1e-66
Identities = 144/356 (40%), Positives = 207/356 (58%), Gaps = 39/356 (10%)
Query: 105 YVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIM 164
+VGF +LP+Q+ KSV +GF F ++ GE+GLGKSTL+++LF T K G
Sbjct: 22 HVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNT------KFEGEPATHT 75
Query: 165 QT-VEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESG 223
Q V++ + D++E VRL+LTIV T GFGD +N + +KP+ E+ID QFE Y ++E
Sbjct: 76 QPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELK 135
Query: 224 LNR--KNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVD 281
+ R D+R+H CLYFI+P GH L+ LD+ MK L +VNI+PI+AKAD ++ E+
Sbjct: 136 IRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELT 195
Query: 282 HKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRV 341
K KI E+ G++IYQFP +DE + + +PFAVIGS ++ + +
Sbjct: 196 KFKIKITSELVSNGVQIYQFPT----DDESVAEINGTMNAHLPFAVIGSTEELKIGNKMM 251
Query: 342 RGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVV 401
R R YPWG V+VEN HCDFVKLR ML+R +M+DL++ T HYE YR
Sbjct: 252 RARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYR------------ 299
Query: 402 KERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKE 457
R KL D TDP+++ ++ E +R E L ++QK+ +E
Sbjct: 300 ----RCKLEEMGFKD---------TDPDSKPFSLQETYEAKR-NEFLGELQKKEEE 341
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,698,563
Number of Sequences: 37866
Number of extensions: 1011220
Number of successful extensions: 5039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 4805
Number of HSP's gapped (non-prelim): 224
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.