Search of human proteins with 17978489

Search of human proteins with 17978489

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
         (742 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]          1531   0.0  
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]          1510   0.0  
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]          1468   0.0  
gi|23397685 egf-like module containing, mucin-like, hormone rece...   848   0.0  
gi|23397693 egf-like module containing, mucin-like, hormone rece...   829   0.0  
gi|23397683 egf-like module containing, mucin-like, hormone rece...   827   0.0  
gi|23397691 egf-like module containing, mucin-like, hormone rece...   808   0.0  
gi|23397681 egf-like module containing, mucin-like, hormone rece...   785   0.0  
gi|23397689 egf-like module containing, mucin-like, hormone rece...   766   0.0  
gi|23397687 egf-like module containing, mucin-like, hormone rece...   555   e-158
gi|40807489 egf-like module containing, mucin-like, hormone rece...   380   e-105
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...   323   5e-88
gi|148806925 EGF, latrophilin and seven transmembrane domain con...   299   7e-81
gi|6912464 latrophilin 2 precursor [Homo sapiens]                     294   2e-79
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]          291   1e-78
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]          291   1e-78
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   280   3e-75
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]             191   2e-48
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...   189   6e-48
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ...   166   7e-41
gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapi...   159   9e-39
gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo sapi...   159   9e-39
gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo sapi...   159   9e-39
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...   158   2e-38
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]   154   2e-37
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]   154   2e-37
gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]   154   2e-37
gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]   154   2e-37
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...   150   4e-36
gi|59710093 G-protein coupled receptor 112 [Homo sapiens]             148   2e-35

>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score = 1531 bits (3964), Expect = 0.0
 Identities = 742/742 (100%), Positives = 742/742 (100%)

Query: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60
           MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
Sbjct: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60

Query: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120
           TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
Sbjct: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120

Query: 121 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ 180
           SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ
Sbjct: 121 SSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQ 180

Query: 181 TLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSN 240
           TLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSN
Sbjct: 181 TLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSN 240

Query: 241 LEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAED 300
           LEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAED
Sbjct: 241 LEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAED 300

Query: 301 PGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN 360
           PGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN
Sbjct: 301 PGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN 360

Query: 361 NTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGC 420
           NTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGC
Sbjct: 361 NTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGC 420

Query: 421 QVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVR 480
           QVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVR
Sbjct: 421 QVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVR 480

Query: 481 PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLE 540
           PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLE
Sbjct: 481 PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLE 540

Query: 541 GLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL 600
           GLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL
Sbjct: 541 GLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFL 600

Query: 601 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW 660
           WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW
Sbjct: 601 WSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTW 660

Query: 661 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEF 720
           VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEF
Sbjct: 661 VFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEF 720

Query: 721 TSTTSGTGHNQTRALRASESGI 742
           TSTTSGTGHNQTRALRASESGI
Sbjct: 721 TSTTSGTGHNQTRALRASESGI 742


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score = 1510 bits (3909), Expect = 0.0
 Identities = 742/786 (94%), Positives = 742/786 (94%), Gaps = 44/786 (5%)

Query: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60
           MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
Sbjct: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60

Query: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120
           TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
Sbjct: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120

Query: 121 --------------------------------------------SSGQHQCDSSTVCFNT 136
                                                       SSGQHQCDSSTVCFNT
Sbjct: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVDECSSGQHQCDSSTVCFNT 180

Query: 137 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS 196
           VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS
Sbjct: 181 VGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDS 240

Query: 197 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP 256
           KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP
Sbjct: 241 KTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGP 300

Query: 257 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT 316
           FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT
Sbjct: 301 FTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTT 360

Query: 317 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL 376
           LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL
Sbjct: 361 LLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHL 420

Query: 377 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH 436
           ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH
Sbjct: 421 ESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSH 480

Query: 437 LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC 496
           LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC
Sbjct: 481 LSSFAILMAHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCIC 540

Query: 497 LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG 556
           LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG
Sbjct: 541 LFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQG 600

Query: 557 LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV 616
           LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV
Sbjct: 601 LSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAV 660

Query: 617 IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY 676
           IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY
Sbjct: 661 IFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTY 720

Query: 677 VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR 736
           VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR
Sbjct: 721 VFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALR 780

Query: 737 ASESGI 742
           ASESGI
Sbjct: 781 ASESGI 786


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score = 1468 bits (3800), Expect = 0.0
 Identities = 733/835 (87%), Positives = 736/835 (88%), Gaps = 93/835 (11%)

Query: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60
           MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
Sbjct: 1   MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE 60

Query: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVD-- 118
           TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVD  
Sbjct: 61  TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC 120

Query: 119 ------------------------------------------ECSSGQHQCDSSTVCFNT 136
                                                     EC+SGQ+ C SST C N 
Sbjct: 121 QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN 180

Query: 137 VGSYSCRCRPGWKP---------------------------------------------- 150
           VGSY CRCRPGW+P                                              
Sbjct: 181 VGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG 240

Query: 151 ---RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 207
              RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN
Sbjct: 241 WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN 300

Query: 208 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 267
           VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL
Sbjct: 301 VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL 360

Query: 268 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 327
           TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS
Sbjct: 361 TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS 420

Query: 328 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 387
           KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP
Sbjct: 421 KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP 480

Query: 388 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 447
           PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY
Sbjct: 481 PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 540

Query: 448 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 507
           DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG
Sbjct: 541 DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG 600

Query: 508 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 567
           IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY
Sbjct: 601 IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY 660

Query: 568 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 627
           GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ
Sbjct: 661 GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ 720

Query: 628 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 687
           KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA
Sbjct: 721 KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA 780

Query: 688 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 742
           FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
Sbjct: 781 FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI 835


>gi|23397685 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform c [Homo sapiens]
          Length = 730

 Score =  848 bits (2192), Expect = 0.0
 Identities = 418/718 (58%), Positives = 519/718 (72%), Gaps = 28/718 (3%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 177
           DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
Sbjct: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 180

Query: 178 HSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQL 237
           HSQTLSRFFDKVQDLGRD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ L
Sbjct: 181 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL 240

Query: 238 LSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAG 297
           L  LED++R L+K+L  G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  
Sbjct: 241 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK 300

Query: 298 AEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFL 357
           + DPGP+V G++SI  M  LLA A L L  +KQ  L E ++  ++      LS V S FL
Sbjct: 301 SGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFL 360

Query: 358 SHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWAT 417
           S+N+T+ L+SP+ F FSH              + V+  PRQ++LC FW+   +  GHWAT
Sbjct: 361 SNNDTQNLSSPVTFTFSH--------------RSVI--PRQKVLCVFWEHGQNGCGHWAT 404

Query: 418 EGCQVLGSKNGSTTCQCSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILT 475
            GC  +G+++ ST C+C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LT
Sbjct: 405 TGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALT 464

Query: 476 FLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFC 535
           FLL + IQ + T++HL L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   
Sbjct: 465 FLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLT 522

Query: 536 WMSLEGLELY-----FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRY 590
           WM LE L L+       VV          + +  +GYGVP + V +SAA     YG P  
Sbjct: 523 WMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSR 582

Query: 591 CWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAI 650
           CWL  E+GF+W FLGPV  I   N V+F+ T+W L  + S +N ++  L+  R L   A 
Sbjct: 583 CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKAT 642

Query: 651 AQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 708
           AQLF+LGCTW  G+      + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 643 AQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 700


>gi|23397693 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform g [Homo sapiens]
          Length = 719

 Score =  829 bits (2142), Expect = 0.0
 Identities = 413/718 (57%), Positives = 511/718 (71%), Gaps = 39/718 (5%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 177
           DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV
Sbjct: 121 DECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV 180

Query: 178 HSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQL 237
           HSQTLSRFFDKVQDLGRD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ L
Sbjct: 181 HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHL 240

Query: 238 LSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAG 297
           L  LED++R L+K+L  G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  
Sbjct: 241 LDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQK 300

Query: 298 AEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFL 357
           + DPG           M  LLA A L L  +KQ  L E ++  ++      LS V S FL
Sbjct: 301 SGDPG-----------MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFL 349

Query: 358 SHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWAT 417
           S+N+T+ L+SP+ F FSH              + V+  PRQ++LC FW+   +  GHWAT
Sbjct: 350 SNNDTQNLSSPVTFTFSH--------------RSVI--PRQKVLCVFWEHGQNGCGHWAT 393

Query: 418 EGCQVLGSKNGSTTCQCSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILT 475
            GC  +G+++ ST C+C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LT
Sbjct: 394 TGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALT 453

Query: 476 FLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFC 535
           FLL + IQ + T++HL L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   
Sbjct: 454 FLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLT 511

Query: 536 WMSLEGLELY-----FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRY 590
           WM LE L L+       VV          + +  +GYGVP + V +SAA     YG P  
Sbjct: 512 WMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSR 571

Query: 591 CWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAI 650
           CWL  E+GF+W FLGPV  I   N V+F+ T+W L  + S +N ++  L+  R L   A 
Sbjct: 572 CWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKAT 631

Query: 651 AQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 708
           AQLF+LGCTW  G+      + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 632 AQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 689


>gi|23397683 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform b [Homo sapiens]
          Length = 774

 Score =  827 bits (2137), Expect = 0.0
 Identities = 418/762 (54%), Positives = 519/762 (68%), Gaps = 72/762 (9%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DEC--------------------------------------------SSGQHQCDSSTVC 133
           DEC                                            SSGQHQCDSSTVC
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDSSTVC 180

Query: 134 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 193
           FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 181 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 194 RDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLP 253
           RD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L 
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 300

Query: 254 KGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 313
            G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPGP+V G++SI  
Sbjct: 301 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPG 360

Query: 314 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAF 373
           M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F F
Sbjct: 361 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 420

Query: 374 SHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQ 433
           SH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+
Sbjct: 421 SH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 464

Query: 434 CSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHL 491
           C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL
Sbjct: 465 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 524

Query: 492 HLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----F 546
            L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+      
Sbjct: 525 QLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNL 582

Query: 547 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 606
            VV          + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGP
Sbjct: 583 TVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGP 642

Query: 607 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 666
           V  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+  
Sbjct: 643 VCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQ 702

Query: 667 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 708
               + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 703 VGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 744


>gi|23397691 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform f [Homo sapiens]
          Length = 763

 Score =  808 bits (2087), Expect = 0.0
 Identities = 413/762 (54%), Positives = 511/762 (67%), Gaps = 83/762 (10%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 DEC--------------------------------------------SSGQHQCDSSTVC 133
           DEC                                            SSGQHQCDSSTVC
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVDECSSGQHQCDSSTVC 180

Query: 134 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 193
           FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG
Sbjct: 181 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 240

Query: 194 RDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLP 253
           RD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L 
Sbjct: 241 RDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLS 300

Query: 254 KGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 313
            G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPG           
Sbjct: 301 NGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG----------- 349

Query: 314 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAF 373
           M  LLA A L L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F F
Sbjct: 350 MGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTF 409

Query: 374 SHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQ 433
           SH              + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+
Sbjct: 410 SH--------------RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICR 453

Query: 434 CSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHL 491
           C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL
Sbjct: 454 CTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHL 513

Query: 492 HLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----F 546
            L +CLF+   +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+      
Sbjct: 514 QLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNL 571

Query: 547 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 606
            VV          + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGP
Sbjct: 572 TVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGP 631

Query: 607 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 666
           V  I   N V+F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+  
Sbjct: 632 VCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQ 691

Query: 667 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWA 708
               + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 692 VGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWS 733


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score =  785 bits (2028), Expect = 0.0
 Identities = 409/811 (50%), Positives = 513/811 (63%), Gaps = 121/811 (14%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 D--------------------------------------------ECSSGQHQCDSSTVC 133
           D                                            EC+SGQ+ C SST C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180

Query: 134 FNTVGSYSCRCRPGWKP------------------------------------------- 150
            N VGSY CRCRPGW+P                                           
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240

Query: 151 ------RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 204
                 RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD K   A  T
Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300

Query: 205 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 264
           IQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L  G   +  P+ 
Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360

Query: 265 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 324
           TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPGP+V G++SI  M  LLA A L 
Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPGPSVVGLVSIPGMGKLLAEAPLV 420

Query: 325 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 384
           L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F FSH         
Sbjct: 421 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 471

Query: 385 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 444
                + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+C+HLSSFA+LM
Sbjct: 472 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 524

Query: 445 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 502
           AHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL L +CLF+   
Sbjct: 525 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 584

Query: 503 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 557
           +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+       VV        
Sbjct: 585 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 642

Query: 558 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 617
             + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGPV  I   N V+
Sbjct: 643 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 702

Query: 618 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 677
           F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+      + V+ Y+
Sbjct: 703 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 762

Query: 678 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 708
           FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 763 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 793


>gi|23397689 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform e [Homo sapiens]
          Length = 812

 Score =  766 bits (1978), Expect = 0.0
 Identities = 404/811 (49%), Positives = 505/811 (62%), Gaps = 132/811 (16%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTLPGAETQDSRGCARWCPQ+SSCVNATACRCNPGFSSFSEIITT
Sbjct: 1   MGGRVFLVFLAFCVWLTLPGAETQDSRGCARWCPQDSSCVNATACRCNPGFSSFSEIITT 60

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P ETCDDINECAT SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV
Sbjct: 61  PMETCDDINECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 120

Query: 118 D--------------------------------------------ECSSGQHQCDSSTVC 133
           D                                            EC+SGQ+ C SST C
Sbjct: 121 DECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHC 180

Query: 134 FNTVGSYSCRCRPGWKP------------------------------------------- 150
            N VGSY CRCRPGW+P                                           
Sbjct: 181 LNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRC 240

Query: 151 ------RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVT 204
                 RHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRD K   A  T
Sbjct: 241 RPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDYKPGLANNT 300

Query: 205 IQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSN 264
           IQ++++ +DEL+EAPGD+E L    +H +A+ LL  LED++R L+K+L  G   +  P+ 
Sbjct: 301 IQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAG 360

Query: 265 TELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLN 324
           TEL+L +Q++ D++VT+ Q+ A M+L+W  A  + DPG           M  LLA A L 
Sbjct: 361 TELSLEVQKQVDRSVTLRQNQAVMQLDWNQAQKSGDPG-----------MGKLLAEAPLV 409

Query: 325 LHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAG 384
           L  +KQ  L E ++  ++      LS V S FLS+N+T+ L+SP+ F FSH         
Sbjct: 410 LEPEKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSH--------- 460

Query: 385 RDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILM 444
                + V+  PRQ++LC FW+   +  GHWAT GC  +G+++ ST C+C+HLSSFA+LM
Sbjct: 461 -----RSVI--PRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLM 513

Query: 445 AHYDV--EDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 502
           AHYDV  ED  LT+IT +GL++SL CLLL  LTFLL + IQ + T++HL L +CLF+   
Sbjct: 514 AHYDVQEEDPVLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHL 573

Query: 503 IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY-----FLVVRVFQGQGL 557
           +FL  I+  G +V   C ++AG LHY +LA   WM LE L L+       VV        
Sbjct: 574 LFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRF 631

Query: 558 STRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVI 617
             + +  +GYGVP + V +SAA     YG P  CWL  E+GF+W FLGPV  I   N V+
Sbjct: 632 MKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLGPVCAIFSVNLVL 691

Query: 618 FVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYV 677
           F+ T+W L  + S +N ++  L+  R L   A AQLF+LGCTW  G+      + V+ Y+
Sbjct: 692 FLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPAARVMAYL 751

Query: 678 FTILNCLQGAFLYLLHCLLNKKVREEYRKWA 708
           FTI+N LQG F++L++CLL+++VRE+Y KW+
Sbjct: 752 FTIINSLQGVFIFLVYCLLSQQVREQYGKWS 782


>gi|23397687 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform d [Homo sapiens]
          Length = 681

 Score =  555 bits (1429), Expect = e-158
 Identities = 307/721 (42%), Positives = 422/721 (58%), Gaps = 83/721 (11%)

Query: 1   MGGRVFL---AFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITT 57
           MGGRVFL   AFCVWLTL                                          
Sbjct: 1   MGGRVFLVFLAFCVWLTL------------------------------------------ 18

Query: 58  PTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDV 117
           P     D   CA      C + S C N      C C+PG+   S   T   E   TC D+
Sbjct: 19  PGAETQDSRGCAR----WCPQDSSCVNATA---CRCNPGFSSFSEIITTPME---TCDDI 68

Query: 118 DECSS-GQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPN--NQKDTVCEDMTFSTWTPP 174
           +EC++  +  C   + C+NT GSY C C PG++P  G     N+ +  C+DMTFSTWTPP
Sbjct: 69  NECATLSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDMTFSTWTPP 128

Query: 175 PGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIA 234
           PGVHSQTLSRFFDKVQDLGRD K   A  TIQ++++ +DEL+EAPGD+E L    +H +A
Sbjct: 129 PGVHSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVA 188

Query: 235 TQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAV 294
           + LL  LED++R L+K+L  G   +  P+ TEL+L +Q++ D++VT+ Q+ A M+L+W  
Sbjct: 189 SHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELSLEVQKQVDRSVTLRQNQAVMQLDWNQ 248

Query: 295 AAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNS 354
           A  + DPGP+V G++SI  M  LLA A L L  +KQ  L E ++  ++      LS V S
Sbjct: 249 AQKSGDPGPSVVGLVSIPGMGKLLAEAPLVLEPEKQMLLHETHQGLLQDGSPILLSDVIS 308

Query: 355 IFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGH 414
            FLS+N+T+ L+SP+ F FSH              + V+  PRQ++LC FW+   +  GH
Sbjct: 309 AFLSNNDTQNLSSPVTFTFSH--------------RSVI--PRQKVLCVFWEHGQNGCGH 352

Query: 415 WATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDV--EDWKLTLITRVGLALSLFCLLLC 472
           WAT GC  +G+++ ST C+C+HLSSFA+LMAHYDV  ED  LT+IT +GL++SL CLLL 
Sbjct: 353 WATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDPVLTVITYMGLSVSLLCLLLA 412

Query: 473 ILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLA 532
            LTFLL + IQ + T++HL L +CLF+   +FL  I+  G +V   C ++AG LHY +LA
Sbjct: 413 ALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLA 470

Query: 533 AFCWMSLEGLELY-----FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGR 587
              WM LE L L+       VV          + +  +GYGVP + V +SAA     YG 
Sbjct: 471 TLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGT 530

Query: 588 PRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTI 647
           P  CWL  E+GF+W FLGPV  I   N V+F+ T+W L  + S +N ++  L+  R L  
Sbjct: 531 PSRCWLQPEKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAF 590

Query: 648 TAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKW 707
            A AQLF+LGCTW  G+      + V+ Y+FTI+N LQG F++L++CLL+++VRE+Y KW
Sbjct: 591 KATAQLFILGCTWCLGILQVGPAARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKW 650

Query: 708 A 708
           +
Sbjct: 651 S 651


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score =  380 bits (977), Expect = e-105
 Identities = 234/745 (31%), Positives = 378/745 (50%), Gaps = 84/745 (11%)

Query: 21  QDSRGCA--RWCPQNSSCVNAT---ACRCNPGFSSFSEIITTP--TETCDDINECATPSK 73
           +D   CA  R CP++++C N     +C CNPGF S S  ++      +C+DI+EC     
Sbjct: 171 EDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCP 230

Query: 74  VSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVC 133
           ++    S C NT GSY C C PG+ P +G   F ++    C+D+DEC      C  +++C
Sbjct: 231 IN----STCTNTPGSYFCTCHPGFAPSNGQLNFTDQGVE-CRDIDECRQDPSTCGPNSIC 285

Query: 134 FNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLG 193
            N +GSYSC C  G+ P         +  C+ + F           + +     ++Q   
Sbjct: 286 TNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKC--------KEDVIPDNKQIQQCQ 337

Query: 194 RDSKTSSAEVT----IQNVIKLVDELMEAPGDVEALAP------PVRHLIAT------QL 237
             +    A V+    I N+  ++D++ E    V +L        PV   I+T      + 
Sbjct: 338 EGTAVKPAYVSFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEE 397

Query: 238 LSNLEDIMRILAKSLPKGPF----TYISPS------NTELTLMIQERGDKNVTMG--QSS 285
            S+L  +     +S+    F      I+P+      + E  ++ +E  ++NVT+      
Sbjct: 398 TSSLATVFLESVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKG 457

Query: 286 ARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQ 345
            +MK+  +    +E         +S   M ++L       H       E         ++
Sbjct: 458 DKMKIGCSTIEESESTETTGVAFVSFVGMESVLNERFFKDHQAPLTTSE---------IK 508

Query: 346 LRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFW 405
           L+  S V    ++       + PI++   +++         P  K   P      +C  W
Sbjct: 509 LKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQ---------PKQKFERP------ICVSW 553

Query: 406 KSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-DWKLTLITRVGLAL 464
            +D  +GG W + GC +L +    T C C+ +++ A++MA  ++  D+ L +I+ VG+ +
Sbjct: 554 STDV-KGGRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIII 612

Query: 465 SLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAG 524
           SL CL+L I TFLL R I+   T +HLHLC+CL +  T+FLAGI     ++G  C ++AG
Sbjct: 613 SLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKMG--CAIIAG 670

Query: 525 LLHYCFLAAFCWMSLEGLELYFLV-----VRVFQGQGLSTRWLCLIGYGVPLLIVGVSAA 579
            LHY FLA F WM +E + L+ +V     V  F  + +    +C  GYG+P+L+V +SA+
Sbjct: 671 FLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISAS 730

Query: 580 IYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKL 639
           +  +GYG    CWL+ E GF+WSFLGPV  +I+ N+++   T+W L Q+ S +N ++  L
Sbjct: 731 VQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTL 790

Query: 640 KKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKK 699
           K  R LT  A AQLF+LGC+WV G+F     + V+ Y+FTI+N LQGAF++L+HCLLN +
Sbjct: 791 KDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQ 850

Query: 700 VREEYRKWACLVAGGSKYSEFTSTT 724
           VREEY++W   + G +K S  + T+
Sbjct: 851 VREEYKRW---ITGKTKPSSQSQTS 872



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 60/162 (37%), Positives = 78/162 (48%), Gaps = 24/162 (14%)

Query: 16  PGAETQDSRGCARW---CPQNSSCVNATA---CRCNPGFSSFSEIITTPTE----TCDDI 65
           PG   +D   C++    C  NSSC N +    C C  GFSS +     P +    +C DI
Sbjct: 74  PGVRCKDIDECSQSPQPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133

Query: 66  NECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH 125
           NEC T S   C + SDC N+ GSY C C  G+              +TC+DVDEC+    
Sbjct: 134 NECLTSSV--CPEHSDCVNSMGSYSCSCQVGF----------ISRNSTCEDVDECAD-PR 180

Query: 126 QCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQ-KDTVCEDM 166
            C     C NTVG+YSC C PG++   G  + Q     CED+
Sbjct: 181 ACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDI 222



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)

Query: 76  CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN 135
           C  ++ C NT  SY C C  G+   +G   FK+     C+D+DECS     C  ++ C N
Sbjct: 41  CPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVR-CKDIDECSQSPQPCGPNSSCKN 99

Query: 136 TVGSYSCRCRPGWKPRHG---IPNNQKDTVCEDM 166
             G Y C C  G+    G   +P    +  C D+
Sbjct: 100 LSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDI 133


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score =  323 bits (827), Expect = 5e-88
 Identities = 213/676 (31%), Positives = 331/676 (48%), Gaps = 85/676 (12%)

Query: 72  SKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQH-QCDSS 130
           +K SC K     +   +  C C+ GY   SG K F    E TC D++EC+      C  +
Sbjct: 24  TKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLE-TCNDINECTPPYSVYCGFN 82

Query: 131 TVCFNTVGSYSCRCRPGWKPRHGIP--NNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDK 188
            VC+N  GS+ C+C PG++   G    +N  +  C+D T S  T       + L +  DK
Sbjct: 83  AVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTTEG----RKELQKIVDK 138

Query: 189 VQDL----------GRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLL 238
            + L          GR   +S+A   +++V   V E         AL  P + ++  Q  
Sbjct: 139 FESLLTNQTLWRTEGRQEISSTATTILRDVESKVLET--------ALKDPEQKVLKIQ-- 188

Query: 239 SNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGA 298
               D + I  +++                   +ER   N+ +  +S  ++ +  +    
Sbjct: 189 ---NDSVAIETQAITDN--------------CSEERKTFNLNVQMNSMDIRCSDIIQGDT 231

Query: 299 EDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLS 358
           +  GP+    +S  ++  ++         KK    +++Y +S           V S  + 
Sbjct: 232 Q--GPSAIAFISYSSLGNIINATFFEEMDKK----DQVYLNS----------QVVSAAIG 275

Query: 359 HNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATE 418
                 L+  +   F H++ +       P  K V         C +WKS + +G  W+ +
Sbjct: 276 PKRNVSLSKSVTLTFQHVKMT-------PSTKKVF--------CVYWKS-TGQGSQWSRD 319

Query: 419 GCQVLGSKNGSTTCQCSHLSSFAILMA-HYDVEDWKLTLITRVGLALSLFCLLLCILTFL 477
           GC ++      T C CSHLSSFA+LMA     ED  LT+IT VGL++SL CLLL  LTFL
Sbjct: 320 GCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEEDPVLTVITYVGLSVSLLCLLLAALTFL 379

Query: 478 LVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWM 537
           L + I+ + T++HL L +CLF+   +FL GI+    +V   C ++AG LHY +LAAF WM
Sbjct: 380 LCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTWM 437

Query: 538 SLEGLELYF----LVVRVFQGQGLSTRWLCL-IGYGVPLLIVGVSAAIYSKGYGRPRYCW 592
            LEG+ L+     L V  +       +W+   +GYGVP + V +SAA +   YG    CW
Sbjct: 438 LLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAISAASWPHLYGTADRCW 497

Query: 593 LDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQ 652
           L  +QGF+WSFLGPV  I   N V+F+   W L +K S +N ++  ++  R L   A AQ
Sbjct: 498 LHLDQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSSLNSEVSTIQNTRMLAFKATAQ 557

Query: 653 LFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVA 712
           LF+LGCTW  GL      + V+ Y+FTI+N LQG F++L++CLL+++V+++Y+KW   + 
Sbjct: 558 LFILGCTWCLGLLQVGPAAQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIV 617

Query: 713 GGSKYSEFTSTTSGTG 728
                SE  + +S  G
Sbjct: 618 KSKSESETYTLSSKMG 633



 Score =  114 bits (285), Expect = 3e-25
 Identities = 55/109 (50%), Positives = 69/109 (63%), Gaps = 2/109 (1%)

Query: 10  CVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFS--EIITTPTETCDDINE 67
           C  L+L GA TQ ++     CP N+SCVN T C CN G++S S  ++ T P ETC+DINE
Sbjct: 11  CFLLSLFGAVTQKTKTSCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINE 70

Query: 68  CATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQD 116
           C  P  V CG  + C+N EGS+ C C PGY   SG + F N +ENTCQD
Sbjct: 71  CTPPYSVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQD 119


>gi|148806925 EGF, latrophilin and seven transmembrane domain
           containing 1 [Homo sapiens]
          Length = 690

 Score =  299 bits (765), Expect = 7e-81
 Identities = 213/698 (30%), Positives = 334/698 (47%), Gaps = 72/698 (10%)

Query: 30  CPQNSSCV---NATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTE 86
           C  N+ C       AC CN GFS     I      C+D NEC   ++ SCG+ ++C NTE
Sbjct: 27  CLPNAKCEIRNGIEACYCNMGFSGNGVTI------CEDDNECGNLTQ-SCGENANCTNTE 79

Query: 87  GSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCF-NTVGSYSCRCR 145
           GSY C+C PG+   S    F       C       +    C    VC    +     + R
Sbjct: 80  GSYYCMCVPGFRSSSNQDRFITNDGTVC-----IENVNANCHLDNVCIAANINKTLTKIR 134

Query: 146 PGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTI 205
              +P   +    +++V       T   P  + +  +    +    LG  + T SA+ T+
Sbjct: 135 SIKEPVALLQEVYRNSV-------TDLSPTDIITY-IEILAESSSLLGYKNNTISAKDTL 186

Query: 206 QN-----VIKLVDELMEAPGDV--EALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFT 258
            N      +K V+  ++    V  + L+   R    T+L+  +E     +++S  K   T
Sbjct: 187 SNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQK--TT 244

Query: 259 YISPSNTELTLMIQERGDKNVT-----MGQSSARMKLNWAVAAGAEDPGPAVAGILSIQN 313
               ++T++ L +      N+      M      + +     A  +  G      +  ++
Sbjct: 245 EFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKS 304

Query: 314 MTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHN--NTKELNSPILF 371
           +  LL+++   L   +  +  E  E        R +S+V S+ +S N     EL   I F
Sbjct: 305 IGPLLSSSDNFLLKPQNYDNSEEEE--------RVISSVISVSMSSNPPTLYELEK-ITF 355

Query: 372 AFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSD-RGGHWATEGCQVLGSKNGST 430
             SH + +D                R   LCAFW    D   G W++EGC++  S    T
Sbjct: 356 TLSHRKVTD----------------RYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHT 399

Query: 431 TCQCSHLSSFAILMA---HYDVEDWK-LTLITRVGLALSLFCLLLCILTFLLVRPIQGSR 486
           +C+C+HL+ FAILM+      ++D+  LT IT++G+ +SL CL +CI TF     IQ +R
Sbjct: 400 SCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTR 459

Query: 487 TTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYF 546
           TTIH +LC  LF+   +FL GI     +  L C ++AGLLHY FLAAF WM +EG+ LY 
Sbjct: 460 TTIHKNLCCSLFLAELVFLVGINTNTNK--LFCSIIAGLLHYFFLAAFAWMCIEGIHLYL 517

Query: 547 LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGP 606
           +VV V   +G   +   + GY  P ++VG SAA+  + YG  + CWL  E  F+WSF+GP
Sbjct: 518 IVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGP 577

Query: 607 VTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFI 666
              IIL N + F   ++K+ +  + + P++   +  R+    A+A LFLLG TW+FG+  
Sbjct: 578 ACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLH 637

Query: 667 FDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEY 704
               S+V  Y+FT+ N  QG F++L  C+L++K++EEY
Sbjct: 638 VVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEY 675


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score =  294 bits (753), Expect = 2e-79
 Identities = 153/368 (41%), Positives = 218/368 (59%), Gaps = 30/368 (8%)

Query: 351  AVNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFW 405
            AVNS  +S +  KE     L  P+LF   H++                P       C+FW
Sbjct: 735  AVNSHVISVSINKESSRVYLTDPVLFTLPHID----------------PDNYFNANCSFW 778

Query: 406  K-SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYD------VEDWKLTLIT 458
              S+    G+W+T+GC+++ +    TTC CSHL++FAILMAH +      V +  LT+IT
Sbjct: 779  NYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDGVHELLLTVIT 838

Query: 459  RVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLR 518
             VG+ +SL CL +CI TF   R +Q  R TIH +LCI LF+   IFL GI+    +  + 
Sbjct: 839  WVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKT--KYAIA 896

Query: 519  CRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSA 578
            C + AGLLH+ FLAAF WM LEG++LY ++V VF+ +    ++  + GY  P  +VGVSA
Sbjct: 897  CPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSA 956

Query: 579  AIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKK 638
            AI  K YG  + CWL  +  F+WSF+GPVTFIIL N +  V T+ K+ +  + + PD  +
Sbjct: 957  AIDYKSYGTEKACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSR 1016

Query: 639  LKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNK 698
            L+  ++  + A A L LLG TW FGL   ++ ++V+ Y+FTI N  QG F+++ HC L K
Sbjct: 1017 LENIKSWVLGAFALLCLLGLTWSFGLLFINEETIVMAYLFTIFNAFQGVFIFIFHCALQK 1076

Query: 699  KVREEYRK 706
            KVR+EY K
Sbjct: 1077 KVRKEYGK 1084


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score =  291 bits (746), Expect = 1e-78
 Identities = 159/399 (39%), Positives = 232/399 (58%), Gaps = 35/399 (8%)

Query: 352  VNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWK 406
            VNS  ++ +  KE     L  P++F  +HLE  +                     C+FW 
Sbjct: 763  VNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN----------------CSFWN 806

Query: 407  -SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWK-----LTLITRV 460
             S+    G+W+T+GC+++ S    TTC CSHL++FA+LMAH ++   +     L++IT V
Sbjct: 807  YSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWV 866

Query: 461  GLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCR 520
            G+ +SL CL +CI TF  +R +Q  R TIH +LCI LF+   +FL GI+    Q  + C 
Sbjct: 867  GIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKT--QYEIACP 924

Query: 521  LVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAI 580
            + AGLLHY FLAAF W+ LEG+ LY L+V VF+ +   T++  L GY  P L+VG++AAI
Sbjct: 925  IFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 984

Query: 581  YSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLK 640
              + YG  + CWL  +  F+WSF+GPV+F+I+ N V  + T+ K+ +  S + PD  +L 
Sbjct: 985  DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1044

Query: 641  KARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKV 700
              ++  + AIA LFLLG TW FGL   +  S+V+ Y+FT  N  QG F+++ HC L KKV
Sbjct: 1045 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1104

Query: 701  REEYRKWACLVAGGSKYSEFTSTTSGT-GHNQTRALRAS 738
             +EY K  CL      Y    S   GT G  +T A+R++
Sbjct: 1105 HKEYSK--CL---RHSYCCIRSPPGGTHGSLKTSAMRSN 1138


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score =  291 bits (746), Expect = 1e-78
 Identities = 159/399 (39%), Positives = 232/399 (58%), Gaps = 35/399 (8%)

Query: 352  VNSIFLSHNNTKE-----LNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWK 406
            VNS  ++ +  KE     L  P++F  +HLE  +                     C+FW 
Sbjct: 758  VNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNAN----------------CSFWN 801

Query: 407  -SDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVEDWK-----LTLITRV 460
             S+    G+W+T+GC+++ S    TTC CSHL++FA+LMAH ++   +     L++IT V
Sbjct: 802  YSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWV 861

Query: 461  GLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCR 520
            G+ +SL CL +CI TF  +R +Q  R TIH +LCI LF+   +FL GI+    Q  + C 
Sbjct: 862  GIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKT--QYEIACP 919

Query: 521  LVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAI 580
            + AGLLHY FLAAF W+ LEG+ LY L+V VF+ +   T++  L GY  P L+VG++AAI
Sbjct: 920  IFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 979

Query: 581  YSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLK 640
              + YG  + CWL  +  F+WSF+GPV+F+I+ N V  + T+ K+ +  S + PD  +L 
Sbjct: 980  DYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLD 1039

Query: 641  KARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKV 700
              ++  + AIA LFLLG TW FGL   +  S+V+ Y+FT  N  QG F+++ HC L KKV
Sbjct: 1040 NIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKV 1099

Query: 701  REEYRKWACLVAGGSKYSEFTSTTSGT-GHNQTRALRAS 738
             +EY K  CL      Y    S   GT G  +T A+R++
Sbjct: 1100 HKEYSK--CL---RHSYCCIRSPPGGTHGSLKTSAMRSN 1133


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  280 bits (717), Expect = 3e-75
 Identities = 155/394 (39%), Positives = 227/394 (57%), Gaps = 25/394 (6%)

Query: 357  LSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELL----CAFWK-SDSDR 411
            LS N++  +NSP++ A  + E S+     DP    V    + E      C+FW  S    
Sbjct: 769  LSTNHSVIVNSPVITAAINKEFSNKVYLADPVVFTVKHIKQSEENFNPNCSFWSYSKRTM 828

Query: 412  GGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE------DWKLTLITRVGLALS 465
             G+W+T+GC++L +    TTC C+HL++FA+LMAH +V+      D  L +IT VG+ LS
Sbjct: 829  TGYWSTQGCRLLTTNKTHTTCSCNHLTNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLS 888

Query: 466  LFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGL 525
            L CLL+CI TF   R +Q  R TIH +LCI LFV   +FL GI      +   C + A L
Sbjct: 889  LVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIA--CAVFAAL 946

Query: 526  LHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGY 585
            LH+ FLAAF WM LEG++LY ++V VF+ +    ++  L+GYG+P LIV VSAA+  + Y
Sbjct: 947  LHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSY 1006

Query: 586  GRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKK---- 641
            G  + CWL  +  F+WSF+GP T II+ N +     ++K+    + + P+   L      
Sbjct: 1007 GTDKVCWLRLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYE 1066

Query: 642  -----ARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLL 696
                  ++  I AIA L LLG TW FGL   ++ ++++ Y+FTI N LQG F+++ HC+L
Sbjct: 1067 DNRPFIKSWVIGAIALLCLLGLTWAFGLMYINESTVIMAYLFTIFNSLQGMFIFIFHCVL 1126

Query: 697  NKKVREEYRKWA---CLVAGGSKYSEFTSTTSGT 727
             KKVR+EY K     C     ++ S  +  TSG+
Sbjct: 1127 QKKVRKEYGKCLRTHCCSGKSTESSIGSGKTSGS 1160


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score =  191 bits (486), Expect = 2e-48
 Identities = 113/316 (35%), Positives = 171/316 (54%), Gaps = 19/316 (6%)

Query: 402 CAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE-----DWKLTL 456
           CAF    S  G  W+  GC +       + C+C+HL++FAILM    +E        L+ 
Sbjct: 510 CAFLDFSSGEGV-WSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSS 568

Query: 457 ITRVGLALSLFCLLLCILTFLL---VRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGG 513
           I+ VG +LS+ CL+  ++TF +   V  I+  R  IH +L   + V   + L     E G
Sbjct: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG 628

Query: 514 QVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLI 573
                C+++A LLHY FL+AF WM +EGL LY +V++VF  +    R+   +G+G PLLI
Sbjct: 629 TTP--CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLI 686

Query: 574 VGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEIN 633
             +S +     YG    CWL    G +W+F+ P  F+I+ N  I +     +T+  S+I+
Sbjct: 687 CIISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIA----VTRVISQIS 742

Query: 634 PDMKKL---KKARALTITAIAQLF-LLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGAFL 689
            D  K+     A  LT  A+A L  +LG +WVFG+   +  ++V  Y+F  LN LQG F+
Sbjct: 743 ADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFI 802

Query: 690 YLLHCLLNKKVREEYR 705
           +L HCLLN +VR  ++
Sbjct: 803 FLFHCLLNSEVRAAFK 818


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score =  189 bits (481), Expect = 6e-48
 Identities = 122/408 (29%), Positives = 196/408 (48%), Gaps = 39/408 (9%)

Query: 333  LEEIYESSIRGVQLRRLSAVNSIFLSHNNTKE-------LNSPILFAFSHLESSDGEAGR 385
            L E Y+   R ++L     +N+  +S     E       L  P+L  F+ LE  +     
Sbjct: 2351 LPERYDPDRRSLRLPHRPIINTPMVSTLVYSEGAPLPRPLERPVLVEFALLEVEE----- 2405

Query: 386  DPPAKDVMPGPRQELLCAFWKSDSDRGGH--WATEGCQVLGSKNGSTTCQCSHLSSFAIL 443
                       R + +C FW      GG   W+  GC++L        CQCSH +SFA+L
Sbjct: 2406 -----------RTKPVCVFWNHSLAVGGTGGWSARGCELLSRNRTHVACQCSHTASFAVL 2454

Query: 444  M---AHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVG 500
            M      + E   L ++T   ++LSL  LL+  +   LVR ++ +  +IH HL + LF+ 
Sbjct: 2455 MDISRRENGEVLPLKIVTYAAVSLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFLS 2514

Query: 501  STIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTR 560
              +F+ GI          C +VA LLHY +++ F W  +E L +Y ++  V        R
Sbjct: 2515 QLVFVIGINQTENP--FLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMR 2572

Query: 561  WLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVT 620
            +  ++G+G+P ++ G++  +  +GYG P +CWL  +   +WSF GP+  +I+ N V  V 
Sbjct: 2573 FYYVVGWGIPAIVTGLAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIINTVTSVL 2632

Query: 621  TVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTI 680
            +     Q+           K   +L  TA   L L+  TW+ GL   +  +L   Y+F I
Sbjct: 2633 SAKVSCQR----KHHYYGKKGIVSLLRTAFLLLLLISATWLLGLLAVNRDALSFHYLFAI 2688

Query: 681  LNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSK-YSEFTSTTSGT 727
             + LQG F+ L HC+LN++VR+  +     V GG K + E ++TT  T
Sbjct: 2689 FSGLQGPFVLLFHCVLNQEVRKHLKG----VLGGRKLHLEDSATTRAT 2732



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 25/113 (22%)

Query: 37   VNATACRCNPGFSSFSEIITTPTETCD-DINECATPSKVSCGKFSDCWNTEGSYDCVCSP 95
            +N   CRC PGF+          + C+ +I+ C +     CG    C + EG Y C C  
Sbjct: 1344 INGLRCRCPPGFTG---------DYCETEIDLCYSD---PCGANGRCRSREGGYTCEC-- 1389

Query: 96   GYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN-TVGSYSCRCRPG 147
                    + F  E          C++G   C +   C N  +G + C C PG
Sbjct: 1390 -------FEDFTGEHCEVDARSGRCANG--VCKNGGTCVNLLIGGFHCVCPPG 1433



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 29/126 (23%), Positives = 43/126 (34%), Gaps = 28/126 (22%)

Query: 24   RGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCW 83
            RGC +      +  N      N      + +     + CD  + C +     C   S C 
Sbjct: 1838 RGCMQGVRMGGTPTNVATLNMN------NALKVRVKDGCDVDDPCTSSP---CPPNSRCH 1888

Query: 84   NTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGS---Y 140
            +    Y CVC  GY  ++            C  VD C    + C++   C  + GS   Y
Sbjct: 1889 DAWEDYSCVCDKGYLGIN------------C--VDACH--LNPCENMGACVRSPGSPQGY 1932

Query: 141  SCRCRP 146
             C C P
Sbjct: 1933 VCECGP 1938


>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
            sapiens]
          Length = 2923

 Score =  166 bits (420), Expect = 7e-41
 Identities = 112/404 (27%), Positives = 189/404 (46%), Gaps = 37/404 (9%)

Query: 319  ANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLS---HNNT----KELNSPILF 371
            A AS+ ++      L   Y+   R +++ +   +N+  +S   H++     + L+ P+  
Sbjct: 2245 AVASVIIYRTLAGLLPHNYDPDKRSLRVPKRPIINTPVVSISVHDDEELLPRALDKPVTV 2304

Query: 372  AFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSD---SDRGGHWATEGCQVLGSKNG 428
             F  LE+ +                R + +C FW      S  GG W+  GC+V+     
Sbjct: 2305 QFRLLETEE----------------RTKPICVFWNHSILVSGTGG-WSARGCEVVFRNES 2347

Query: 429  STTCQCSHLSSFAILM---AHYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGS 485
              +CQC+H++SFA+LM      + E   L  +T V L ++L  LLL      L+R ++ +
Sbjct: 2348 HVSCQCNHMTSFAVLMDVSRRENGEILPLKTLTYVALGVTLAALLLTFFFLTLLRILRSN 2407

Query: 486  RTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELY 545
            +  I  +L   L +   +FL GI      +   C ++A LLH+ +L  F W  LE L LY
Sbjct: 2408 QHGIRRNLTAALGLAQLVFLLGINQ--ADLPFACTVIAILLHFLYLCTFSWALLEALHLY 2465

Query: 546  FLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLG 605
              +  V        R+  ++G+GVP  I G++  +  +GYG P +CWL      +WSF G
Sbjct: 2466 RALTEVRDVNTGPMRFYYMLGWGVPAFITGLAVGLDPEGYGNPDFCWLSIYDTLIWSFAG 2525

Query: 606  PVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF 665
            PV F +  +  +++          +      +K      L   + A L LL  TW+  L 
Sbjct: 2526 PVAFAVSMSVFLYILAA---RASCAAQRQGFEKKGPVSGLQ-PSFAVLLLLSATWLLALL 2581

Query: 666  IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 709
              +  +L+  Y+F   NC+QG F++L + +L+K+VR+   K AC
Sbjct: 2582 SVNSDTLLFHYLFATCNCIQGPFIFLSYVVLSKEVRKAL-KLAC 2624



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 30/112 (26%), Positives = 38/112 (33%), Gaps = 23/112 (20%)

Query: 37   VNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPG 96
            V    CRC PGF+   +   T  + C             CG    C + EG Y C+C  G
Sbjct: 1269 VGGLRCRCPPGFTG--DYCETEVDLC---------YSRPCGPHGRCRSREGGYTCLCRDG 1317

Query: 97   YEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN-TVGSYSCRCRPG 147
            Y           E          C+ G   C +   C N  VG + C C  G
Sbjct: 1318 Y---------TGEHCEVSARSGRCTPG--VCKNGGTCVNLLVGGFKCDCPSG 1358



 Score = 33.1 bits (74), Expect = 0.96
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%)

Query: 111  ENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGW 148
            E  C   D C S  + C +++ C N   SYSC C PG+
Sbjct: 1788 EQGCSLPDPCDS--NPCPANSYCSNDWDSYSCSCDPGY 1823



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 19/76 (25%)

Query: 76   CGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFN 135
            C   S C N   SY C C PGY        + +   N C D++ C   +HQ    +VC  
Sbjct: 1802 CPANSYCSNDWDSYSCSCDPGY--------YGDNCTNVC-DLNPC---EHQ----SVCTR 1845

Query: 136  TVGS---YSCRCRPGW 148
               +   Y+C C P +
Sbjct: 1846 KPSAPHGYTCECPPNY 1861


>gi|223556012 G-protein coupled receptor 113 isoform 1 [Homo sapiens]
          Length = 1079

 Score =  159 bits (402), Expect = 9e-39
 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%)

Query: 402  CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 458
            C FW     +G G W+ EGCQ  + S + +  C C HL++F++LM+ + V E+  L L+T
Sbjct: 715  CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 774

Query: 459  RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 512
            +VGL  S+  LL+C+  + LV        I   R    L++  CL    T FL       
Sbjct: 775  QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 834

Query: 513  GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 570
            G     C   A L H+ +LA F WM  + L L   ++ VF    +      + L+GY  P
Sbjct: 835  GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 894

Query: 571  LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 628
            L + GV+  +Y     Y R   CWLD + G L++F+GPV  II  N ++    + KL + 
Sbjct: 895  LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 954

Query: 629  FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 687
                 P  +K +    +    +    + G TW  GL  + ++ S V  Y+FTILN LQG 
Sbjct: 955  SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 1014

Query: 688  FLYLLHCLLNKKVREEYRKWAC 709
            F+ L  CL+++K++E  RK  C
Sbjct: 1015 FILLFGCLMDRKIQEALRKRFC 1036


>gi|223556014 G-protein coupled receptor 113 isoform 2 [Homo
           sapiens]
          Length = 997

 Score =  159 bits (402), Expect = 9e-39
 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%)

Query: 402 CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 458
           C FW     +G G W+ EGCQ  + S + +  C C HL++F++LM+ + V E+  L L+T
Sbjct: 646 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 705

Query: 459 RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 512
           +VGL  S+  LL+C+  + LV        I   R    L++  CL    T FL       
Sbjct: 706 QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 765

Query: 513 GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 570
           G     C   A L H+ +LA F WM  + L L   ++ VF    +      + L+GY  P
Sbjct: 766 GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 825

Query: 571 LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 628
           L + GV+  +Y     Y R   CWLD + G L++F+GPV  II  N ++    + KL + 
Sbjct: 826 LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 885

Query: 629 FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 687
                P  +K +    +    +    + G TW  GL  + ++ S V  Y+FTILN LQG 
Sbjct: 886 SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 945

Query: 688 FLYLLHCLLNKKVREEYRKWAC 709
           F+ L  CL+++K++E  RK  C
Sbjct: 946 FILLFGCLMDRKIQEALRKRFC 967


>gi|141802362 G-protein coupled receptor 113 isoform 3 [Homo
           sapiens]
          Length = 873

 Score =  159 bits (402), Expect = 9e-39
 Identities = 106/322 (32%), Positives = 160/322 (49%), Gaps = 14/322 (4%)

Query: 402 CAFWKSDSDRG-GHWATEGCQV-LGSKNGSTTCQCSHLSSFAILMAHYDV-EDWKLTLIT 458
           C FW     +G G W+ EGCQ  + S + +  C C HL++F++LM+ + V E+  L L+T
Sbjct: 516 CVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLT 575

Query: 459 RVGLALSLFCLLLCILTFLLV------RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEG 512
           +VGL  S+  LL+C+  + LV        I   R    L++  CL    T FL       
Sbjct: 576 QVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSP 635

Query: 513 GQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQ--GQGLSTRWLCLIGYGVP 570
           G     C   A L H+ +LA F WM  + L L   ++ VF    +      + L+GY  P
Sbjct: 636 GPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCP 695

Query: 571 LLIVGVSAAIY--SKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQK 628
           L + GV+  +Y     Y R   CWLD + G L++F+GPV  II  N ++    + KL + 
Sbjct: 696 LGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRP 755

Query: 629 FSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLF-IFDDRSLVLTYVFTILNCLQGA 687
                P  +K +    +    +    + G TW  GL  + ++ S V  Y+FTILN LQG 
Sbjct: 756 SLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGV 815

Query: 688 FLYLLHCLLNKKVREEYRKWAC 709
           F+ L  CL+++K++E  RK  C
Sbjct: 816 FILLFGCLMDRKIQEALRKRFC 837


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score =  158 bits (399), Expect = 2e-38
 Identities = 109/389 (28%), Positives = 183/389 (47%), Gaps = 40/389 (10%)

Query: 337  YESSIRGVQLRRLSAVNS------IFLSHNNTKE-LNSPILFAFSHLESSDGEAGRDPPA 389
            +++  RG +L +   +NS      +F   N  +  L SPI   F  L++++         
Sbjct: 2424 FQAERRGARLPQNPVMNSPVVSVAVFHGRNFLRGILESPISLEFRLLQTAN--------- 2474

Query: 390  KDVMPGPRQELLCAFWKSD--SDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY 447
                   R + +C  W     +++ G W    C+++        C+CS   +F +LM   
Sbjct: 2475 -------RSKAICVQWDPPGLAEQHGVWTARDCELVHRNGSHARCRCSRTGTFGVLMDAS 2527

Query: 448  DVEDWK-----LTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGST 502
              E  +     L + T V +A+S+  L+L     L +R ++ +   IH ++   L V   
Sbjct: 2528 PRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNVRGIHANVAAALGVAEL 2587

Query: 503  IFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWL 562
            +FL GI     Q  L C  VA LLHY FL+ F W+ ++GL LY + V        + R+ 
Sbjct: 2588 LFLLGIHRTHNQ--LVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFY 2645

Query: 563  CLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTV 622
              +G+GVP +++G++  +  +GYG P +CW+   +  +WSF GPV  +I+ N  +F    
Sbjct: 2646 HALGWGVPAVLLGLAVGLDPEGYGNPDFCWISVHEPLIWSFAGPVVLVIVMNGTMF---- 2701

Query: 623  WKLTQKFSEINPDMKKLKKARALTI-TAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTIL 681
              L    +  +   ++ KK  ALT+ ++   L L+  +W+FGL   +   L   Y+   L
Sbjct: 2702 --LLAARTSCSTGQREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHSILAFHYLHAGL 2759

Query: 682  NCLQGAFLYLLHCLLNKKVREEYRKWACL 710
              LQG  + LL C+LN   R  +   ACL
Sbjct: 2760 CGLQGLAVLLLFCVLNADARAAWMP-ACL 2787



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 28/107 (26%), Positives = 37/107 (34%), Gaps = 23/107 (21%)

Query: 42   CRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVS 101
            CRC PGF+   +   T  + C      + P    C     C   EG Y CVC P      
Sbjct: 1421 CRCPPGFTG--DFCETELDLC-----YSNP----CRNGGACARREGGYTCVCRP------ 1463

Query: 102  GAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTV-GSYSCRCRPG 147
                F  E      +   C  G   C +   C +   G + C+C  G
Sbjct: 1464 ---RFTGEDCELDTEAGRCVPG--VCRNGGTCTDAPNGGFRCQCPAG 1505


>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
          Length = 995

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 161 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 215
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 327 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 386

Query: 216 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 275
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 387 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 434

Query: 276 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 335
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 435 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 494

Query: 336 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 391
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 495 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 544

Query: 392 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 445
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 545 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 597

Query: 446 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 504
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 598 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 657

Query: 505 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 563
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 658 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 717

Query: 564 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 612
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 718 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 777

Query: 613 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 665
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 778 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 829

Query: 666 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 709
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 830 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 873


>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
          Length = 1003

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 161 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 215
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 335 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 394

Query: 216 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 275
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 395 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 442

Query: 276 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 335
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 443 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 502

Query: 336 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 391
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 503 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 552

Query: 392 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 445
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 553 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 605

Query: 446 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 504
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 606 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 665

Query: 505 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 563
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 666 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 725

Query: 564 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 612
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 726 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 785

Query: 613 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 665
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 786 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 837

Query: 666 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 709
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 838 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 881


>gi|119943120 G protein-coupled receptor 64 isoform 1 [Homo sapiens]
          Length = 1017

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 161 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 215
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 349 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 408

Query: 216 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 275
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 409 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 456

Query: 276 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 335
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 457 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 516

Query: 336 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 391
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 517 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 566

Query: 392 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 445
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 567 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 619

Query: 446 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 504
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 620 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 679

Query: 505 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 563
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 680 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 739

Query: 564 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 612
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 740 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 799

Query: 613 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 665
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 800 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 851

Query: 666 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 709
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 852 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 895


>gi|119943129 G protein-coupled receptor 64 isoform 4 [Homo sapiens]
          Length = 1014

 Score =  154 bits (390), Expect = 2e-37
 Identities = 146/584 (25%), Positives = 248/584 (42%), Gaps = 72/584 (12%)

Query: 161 TVCEDMTFSTWTPPPG----VHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN-VIKLVDEL 215
           TV      +T + PP     V++ ++S   ++V  + +     S E  +   +I  V  L
Sbjct: 346 TVSAPANVNTTSAPPVQTDIVNTSSISDLENQVLQMEKALSLGSLEPNLAGEMINQVSRL 405

Query: 216 MEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERG 275
           + +P D+  LAP     +A +LL  ++DI   L  S      T IS ++  L L +    
Sbjct: 406 LHSPPDM--LAP-----LAQRLLKVVDDIGLQLNFSN-----TTISLTSPSLALAVIRVN 453

Query: 276 DKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEE 335
             +       A+   N  V+   + P  ++  I    ++   L    + L S+ Q    E
Sbjct: 454 ASSFNTTTFVAQDPANLQVSLETQAPENSIGTITLPSSLMNNLPAHDMELASRVQFNFFE 513

Query: 336 ----IYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKD 391
                 + S+  + L  +S V S  +++   + L   +     H+  S  E         
Sbjct: 514 TPALFQDPSLENLSL--ISYVISSSVANLTVRNLTRNVTVTLKHINPSQDEL-------- 563

Query: 392 VMPGPRQELLCAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----A 445
                   + C FW    + G G W+  GC V   +   T C CSHL+SF +L+     +
Sbjct: 564 -------TVRCVFWDLGRNGGRGGWSDNGCSVKDRRLNETICTCSHLTSFGVLLDLSRTS 616

Query: 446 HYDVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIF 504
               +   LT IT +G  LS   L + ++T++    I+    + I + LC  L + + +F
Sbjct: 617 VLPAQMMALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVF 676

Query: 505 LAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLC 563
           L        ++   C  VA  LHY  L +F WM LE   +Y  +V+VF           C
Sbjct: 677 LLDSWIALYKMQGLCISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFC 736

Query: 564 LIGYGVPLLIVGVSAAIYSKGYGRPRY-----------CWLDFEQGFLWSFLGPVTFIIL 612
           ++G+GVP ++V +   I    YG   Y           CW++    F  + +G    I L
Sbjct: 737 IVGWGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNNAVFYITVVGYFCVIFL 796

Query: 613 CNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQL-------FLLGCTWVFGLF 665
            N  +F+  + +L +        +KK K+  A   T+I  L       FLLG TW F  F
Sbjct: 797 LNVSMFIVVLVQLCR--------IKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFF 848

Query: 666 IFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWAC 709
            +   ++   Y+F I N LQG F+++ +C+  + VR+++R++ C
Sbjct: 849 AWGPVNVTFMYLFAIFNTLQGFFIFIFYCVAKENVRKQWRRYLC 892


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score =  150 bits (379), Expect = 4e-36
 Identities = 95/297 (31%), Positives = 157/297 (52%), Gaps = 12/297 (4%)

Query: 413  GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM---AHYDVEDWKLTLITR-VGLALSLFC 468
            G W+  GC+ +      T C C  LS+FAIL    A  ++E   L  +T  VG  +S   
Sbjct: 902  GPWSWRGCRTVPLDALRTRCLCDRLSTFAILAQLSADANMEKATLPSVTLIVGCGVSSLT 961

Query: 469  LLLCILTFLLV-RPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLH 527
            LL+ ++ ++ V R I+  R+ I ++ C+ +   + + L G      +V   C LVA  LH
Sbjct: 962  LLMLVIIYVSVWRYIRSERSVILINFCLSIISSNALILIGQTQTRNKVV--CTLVAAFLH 1019

Query: 528  YCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIY-SKGYG 586
            + FL++FCW+  E  + Y  V    + + +  R+LCL G+G+P L+V +S     +KGY 
Sbjct: 1020 FFFLSSFCWVLTEAWQSYMAVTGHLRNRLIRKRFLCL-GWGLPALVVAISVGFTKAKGYS 1078

Query: 587  RPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALT 646
               YCWL  E G L++F+GP   ++L N VI +    KL  K  +   D K  ++A A  
Sbjct: 1079 TMNYCWLSLEGGLLYAFVGPAAAVVLVNMVIGILVFNKLVSK--DGITDKKLKERAGASL 1136

Query: 647  ITAIAQLFLLGCTWVFG-LFIFDDRSLVLTYVFTILNCLQGAFLYLLHCLLNKKVRE 702
             ++   L LL  TW+   L + D RS +   +F + + L+G  + ++HC+L ++V++
Sbjct: 1137 WSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDSLEGFVIVMVHCILRREVQD 1193


>gi|59710093 G-protein coupled receptor 112 [Homo sapiens]
          Length = 3080

 Score =  148 bits (374), Expect = 2e-35
 Identities = 97/325 (29%), Positives = 155/325 (47%), Gaps = 24/325 (7%)

Query: 402  CAFWKSDSDRG-GHWATEGCQVLGSKNGSTTCQCSHLSSFAILM-----AHYDVEDWKLT 455
            CAFW  +++ G G W + GC+V  +    T CQC HL+ F +LM         V +  L 
Sbjct: 2685 CAFWDFENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILA 2744

Query: 456  LITRVGLALSLFCLLLCILTFLLVRPIQGSRTT-IHLHLCICLFVGSTIFLAGIENEGGQ 514
            LIT  G  +S   L + ++T++    ++      I ++LC  L + + +FL        Q
Sbjct: 2745 LITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQ 2804

Query: 515  VGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLS-TRWLCLIGYGVPLLI 573
                C   A  LHY  L +F WM LE + +Y  +V+VF     +     CL+G+G+P ++
Sbjct: 2805 KVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIM 2864

Query: 574  VGVSAAIYSKGYGR----PRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKF 629
            V ++ ++    YG       +CW+  +  F  S +     I L N  +F T + +L    
Sbjct: 2865 VAITVSVKKDLYGTLSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVK 2924

Query: 630  SEINPDMKK-----LKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCL 684
            S+I    +K     LK   +LT       FLLG TW F  F +        Y+F I N L
Sbjct: 2925 SQIQKTRRKMILHDLKGTMSLT-------FLLGLTWGFAFFAWGPMRNFFLYLFAIFNTL 2977

Query: 685  QGAFLYLLHCLLNKKVREEYRKWAC 709
            QG F+++ HC++ + VRE+++   C
Sbjct: 2978 QGFFIFVFHCVMKESVREQWQIHLC 3002


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,371,806
Number of Sequences: 37866
Number of extensions: 1426959
Number of successful extensions: 6199
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 3700
Number of HSP's gapped (non-prelim): 1094
length of query: 742
length of database: 18,247,518
effective HSP length: 110
effective length of query: 632
effective length of database: 14,082,258
effective search space: 8899987056
effective search space used: 8899987056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.