Guide to the Human Genome
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Search of human proteins with 170763493

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170763493 tumor-suppressing subtransferable candidate 6
[Homo sapiens]
         (320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170763493 tumor-suppressing subtransferable candidate 6 [Homo...   648   0.0  
gi|21264580 tetraspan 2 [Homo sapiens]                                 42   7e-04
gi|4757944 CD81 antigen [Homo sapiens]                                 39   0.008
gi|4502693 CD9 antigen [Homo sapiens]                                  35   0.12 
gi|134288906 tripartite motif-containing 67 [Homo sapiens]             30   2.9  
gi|29725609 epidermal growth factor receptor isoform a precursor...    30   3.7  
gi|126012573 low density lipoprotein-related protein 2 [Homo sap...    30   3.7  
gi|5453810 netrin 3 [Homo sapiens]                                     29   4.9  
gi|222831660 family with sequence similarity 171, member A2 [Hom...    29   6.4  
gi|187607445 hypothetical protein LOC79137 [Homo sapiens]              29   6.4  
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]         28   8.3  

>gi|170763493 tumor-suppressing subtransferable candidate 6 [Homo
           sapiens]
          Length = 320

 Score =  648 bits (1672), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MGPWSRVRVAKCQMLVTCFFILLLGLSVATMVTLTYFGAHFAVIRRASLEKNPYQAVHQW 60
           MGPWSRVRVAKCQMLVTCFFILLLGLSVATMVTLTYFGAHFAVIRRASLEKNPYQAVHQW
Sbjct: 1   MGPWSRVRVAKCQMLVTCFFILLLGLSVATMVTLTYFGAHFAVIRRASLEKNPYQAVHQW 60

Query: 61  AFSAGLSLVGLLTLGAVLSAAATVREAQGLMAGGFLCFSLAFCAQVQVVFWRLHSPTQVE 120
           AFSAGLSLVGLLTLGAVLSAAATVREAQGLMAGGFLCFSLAFCAQVQVVFWRLHSPTQVE
Sbjct: 61  AFSAGLSLVGLLTLGAVLSAAATVREAQGLMAGGFLCFSLAFCAQVQVVFWRLHSPTQVE 120

Query: 121 DAMLDTYDLVYEQAMKGTSHVRRQELAAIQDVFLCCGKKSPFSRLGSTEADLCQGEEAAR 180
           DAMLDTYDLVYEQAMKGTSHVRRQELAAIQDVFLCCGKKSPFSRLGSTEADLCQGEEAAR
Sbjct: 121 DAMLDTYDLVYEQAMKGTSHVRRQELAAIQDVFLCCGKKSPFSRLGSTEADLCQGEEAAR 180

Query: 181 EDCLQGIRSFLRTHQQVASSLTSIGLALTVSALLFSSFLWFAIRCGCSLDRKGKYTLTPR 240
           EDCLQGIRSFLRTHQQVASSLTSIGLALTVSALLFSSFLWFAIRCGCSLDRKGKYTLTPR
Sbjct: 181 EDCLQGIRSFLRTHQQVASSLTSIGLALTVSALLFSSFLWFAIRCGCSLDRKGKYTLTPR 240

Query: 241 ACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQESDAAPLPLSCHLAAHR 300
           ACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQESDAAPLPLSCHLAAHR
Sbjct: 241 ACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQESDAAPLPLSCHLAAHR 300

Query: 301 ALQGRSRGGLSGCPERGLSD 320
           ALQGRSRGGLSGCPERGLSD
Sbjct: 301 ALQGRSRGGLSGCPERGLSD 320


>gi|21264580 tetraspan 2 [Homo sapiens]
          Length = 221

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 53/221 (23%), Positives = 87/221 (39%), Gaps = 29/221 (13%)

Query: 18  CFFILLLGLSVATMVT---LTYFGAHF----AVIRRASLEKNPYQAVHQWAFSAGLSLVG 70
           C   LLLG ++   +    +  FG  F    A+   +S +K+P        F  GL +  
Sbjct: 10  CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEY------FYVGLYV-- 61

Query: 71  LLTLGAVLSAAA------TVREAQGLMAGGFLCFSLAFCAQVQVVFWRLHSPTQVEDAML 124
           L+  GA++ A         +RE+Q ++   F C  + F A+V    +           + 
Sbjct: 62  LVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQ 121

Query: 125 DTYDLVYEQAMKGTSHVRRQELAAIQDVFLCCGKKSPFSRLGSTEADLCQGEEAAREDCL 184
             Y+  Y   +K         L      F CCGK+S            C  E    ++C+
Sbjct: 122 TMYEEAYNDYLKDRGK-GNGTLITFHSTFQCCGKES-----SEQVQPTCPKELLGHKNCI 175

Query: 185 QGIRSFLRTHQQVASSLTSIGLA-LTVSALLFSSFLWFAIR 224
             I + +    Q+   +  IG+A LT+  ++FS  L  AIR
Sbjct: 176 DEIETIISVKLQLI-GIVGIGIAGLTIFGMIFSMVLCCAIR 215


>gi|4757944 CD81 antigen [Homo sapiens]
          Length = 236

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 39/171 (22%), Positives = 67/171 (39%), Gaps = 21/171 (12%)

Query: 71  LLTLGAV------LSAAATVREAQGLMAGGFLCFSLAFCAQVQVVFWRLHSPTQVEDAML 124
           L+ +GAV      L     ++E+Q L+   F C  + F  +V    W   +  Q+   + 
Sbjct: 65  LIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVK 124

Query: 125 DTYDLVYEQA-MKGTSHVRRQELAAIQDVFLCCGKKSPFSRLGST-EADLCQG-----EE 177
             YD   +QA +   ++  +  +    +   CCG  +  +   S  + +LC         
Sbjct: 125 QFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISN 184

Query: 178 AAREDCLQGIRSFLRTHQQVASSLTSIGLALTVSA--LLFSSFLWFAIRCG 226
             +EDC Q I          +  L  IG+A  V A  ++F   L   + CG
Sbjct: 185 LFKEDCHQKIDDLF------SGKLYLIGIAAIVVAVIMIFEMILSMVLCCG 229


>gi|4502693 CD9 antigen [Homo sapiens]
          Length = 228

 Score = 34.7 bits (78), Expect = 0.12
 Identities = 34/159 (21%), Positives = 63/159 (39%), Gaps = 10/159 (6%)

Query: 71  LLTLGAVLSAAATVREAQGLMAGGFLCFSLAFCAQVQVVFWRLHSPTQVEDAMLDTYDLV 130
           L+ L   L     V+E+Q ++   F    + F  ++    W      +V   + + Y   
Sbjct: 69  LMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDT 128

Query: 131 YEQAMKGTSHVRRQELAAIQDVFLCCGKKSPFSRLGSTEADLCQGEEAAR----EDCLQG 186
           Y + +K     +R+ L AI     CCG      +  S   D+C  ++       + C   
Sbjct: 129 YNK-LKTKDEPQRETLKAIHYALNCCGLAGGVEQFIS---DICPKKDVLETFTVKSCPDA 184

Query: 187 IRSFLRTHQQVASSLTSIGLALT-VSALLFSSFLWFAIR 224
           I+        +  ++  IG+A+  +  ++FS  L  AIR
Sbjct: 185 IKEVFDNKFHIIGAV-GIGIAVVMIFGMIFSMILCCAIR 222


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 21/76 (27%), Positives = 25/76 (32%), Gaps = 1/76 (1%)

Query: 242 CGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQESDAAPLPLSCHLAAHRA 301
           C R P EP+   C Q    +C   +      RG     R +Q     P P          
Sbjct: 211 CDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTGT 270

Query: 302 LQGRSRGGLSGCPERG 317
            QG   GG  GC   G
Sbjct: 271 AQGAPSGG-GGCKSPG 285


>gi|29725609 epidermal growth factor receptor isoform a precursor
           [Homo sapiens]
          Length = 1210

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 14/76 (18%)

Query: 252 LRCSQGGPTHCLHSEAVAIGPR----------GCSGSLRWLQESDAAPLPLSCHLAAHRA 301
           + C+  GP +C+       GP           G + +L W + +DA  +   CHL     
Sbjct: 569 ITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVW-KYADAGHV---CHLCHPNC 624

Query: 302 LQGRSRGGLSGCPERG 317
             G +  GL GCP  G
Sbjct: 625 TYGCTGPGLEGCPTNG 640


>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
          Length = 4655

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 9/52 (17%)

Query: 240  RACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQESDAAPLP 291
            R C  +   P   +C+ G   HC+HSE        C GS   L  SD A  P
Sbjct: 3791 RDCEMRTCHPEYFQCTSG---HCVHSEL------KCDGSADCLDASDEADCP 3833


>gi|5453810 netrin 3 [Homo sapiens]
          Length = 580

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 6/72 (8%)

Query: 233 GKYTLTPRACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLRWLQES-DAAPLP 291
           G+  L    CGR    P+   C    P    HS A+   P G +  L W  ES   APL 
Sbjct: 50  GREVLASSTCGR----PATRACDASDPRRA-HSPALLTSPGGTASPLCWRSESLPRAPLN 104

Query: 292 LSCHLAAHRALQ 303
           ++  +   +A +
Sbjct: 105 VTLTVPLGKAFE 116


>gi|222831660 family with sequence similarity 171, member A2 [Homo
           sapiens]
          Length = 826

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 14/79 (17%)

Query: 239 PRACGRQPQEPSLLRCSQGGPTHCLHSEAVAIGP-----------RGCSGSLRWLQESDA 287
           PR+  R   EPS  R   GG +  L     A GP           RG SG+  +L E  +
Sbjct: 420 PRSASRPAAEPSGAR---GGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPS 476

Query: 288 APLPLSCHLAAHRALQGRS 306
            P P   +L    A +G++
Sbjct: 477 PPPPFDHYLGHKGAAEGKT 495


>gi|187607445 hypothetical protein LOC79137 [Homo sapiens]
          Length = 543

 Score = 28.9 bits (63), Expect = 6.4
 Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 3/46 (6%)

Query: 249 PSLLRCSQGGPTHCLHSEAVAIGPRGCSGSLR---WLQESDAAPLP 291
           P  ++CS GGP   L  E V+ G     G+L     L  SD AP P
Sbjct: 419 PDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSP 464


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score = 28.5 bits (62), Expect = 8.3
 Identities = 39/180 (21%), Positives = 75/180 (41%), Gaps = 31/180 (17%)

Query: 71  LLTLGAV------LSAAATVREAQGLMAGGFLCFSLAFCAQVQV----VFWRLHSPTQVE 120
           L+ +GA+      L     ++E++ ++   F+   L    QV        ++  S   V 
Sbjct: 59  LIAVGAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVN 118

Query: 121 DAMLDTYDLVYEQAMKGTSHVRRQE-LAAIQDVFLCCGKKSPFSRLGST---EADLC--- 173
           + + +   L+   +  G S  + QE +   Q+ F CCG  +  +  G+      +LC   
Sbjct: 119 ETLYENTKLL---SATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACL 175

Query: 174 ---------QGEEAAREDCLQGIRSFLRTHQQVASSLTSIGLA-LTVSALLFSSFLWFAI 223
                     G++  +E C+  I+ FL  +  +   + S GLA + +  L+FS  L+  I
Sbjct: 176 DKQRPCQSYNGKQVYKETCISFIKDFLAKNLIIVIGI-SFGLAVIEILGLVFSMVLYCQI 234


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.136    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,196,021
Number of Sequences: 37866
Number of extensions: 534288
Number of successful extensions: 1679
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1674
Number of HSP's gapped (non-prelim): 13
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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